TWAS hub - MAST4

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Artery Tibial	0.1814	0.0515	1.1e-04	0.101	NA	0.117	NA	0.103	2.5e-08	NA	1.9e-09	NA	1.8e-08
2	GTEx	Cells Transformed fibroblasts	0.1600	0.0470	3.2e-04	0.062	NA	0.086	NA	0.080	1.9e-05	NA	5.6e-07	NA	1.3e-06
3	GTEx	Colon Transverse	0.2490	0.0820	3.5e-03	0.065	NA	0.020	NA	0.039	5.0e-04	NA	3.6e-02	NA	6.0e-03
4	GTEx	Heart Left Ventricle	0.2653	0.0603	1.4e-06	0.275	NA	0.244	NA	0.284	5.4e-15	NA	3.2e-13	NA	1.8e-15
5	GTEx	Muscle Skeletal	0.1578	0.0351	5.6e-07	0.113	NA	0.132	NA	0.140	3.8e-11	NA	6.3e-13	NA	1.2e-13
6	GTEx	Skin Sun Exposed Lower leg	0.3110	0.0690	1.4e-04	-0.003	NA	-0.003	NA	-0.002	9.8e-01	NA	7.8e-01	NA	5.8e-01
7	GTEx	Whole Blood	0.1380	0.0570	6.6e-03	0.061	NA	0.004	NA	0.031	2.5e-06	NA	1.3e-01	NA	7.3e-04
8	METSIM	Adipose	0.0763	0.0255	6.1e-04	-0.001	0.021	0.008	0.021	0.000	4.0e-01	0.00032	1.8e-02	0.00032	2.7e-01
9	ROSMAP	Brain Pre-frontal Cortex	0.0501	0.0255	3.3e-02	0.006	0.003	0.000	0.013	0.010	5.4e-02	0.14000	3.6e-01	0.00690	1.4e-02
10	TCGA	Thyroid Carcinoma	0.0790	0.0280	2.9e-04	0.026	0.027	0.012	NA	0.030	1.3e-03	0.00098	2.3e-02	NA	5.5e-04

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10
Angina (self-reported)	4.8	6.3	15.8	3.4	4.0	3.4	0.7	3.1	-1.3	1.0	3.0	-0.1	-1.4
Angina	4.7	6.2	15.7	3.3	4.0	3.5	0.4	3.0	-1.3	1.0	3.2	-0.0	-1.1
Bipolar Disorder (2011)	4.4	4.3	14.1	2.6	1.8	3.8	-1.6	3.4	1.2	1.1	0.0	-0.5	1.3
Type 2 Diabetes (T2D) (2012)	3.6	4.2	11.3	-3.1	-3.4	-2.8	-0.2	-2.6	1.4	-0.9	-1.4	0.0	1.0
Qualifications: nursing, teaching	3.6	5.7	16.4	4.0	3.4	2.4	1.5	4.0	1.2	1.0	-0.2	1.0	1.0
Mouth/teeth dental problems: Bleeding gums	3.3	4.2	14.7	-3.8	-1.9	-3.0	0.0	-3.2	-0.6	0.5	0.4	1.5	-1.3
Illnesses of father: Heart disease	3.0	4.2	15.1	3.0	3.9	2.8	-0.5	2.7	0.0	-0.1	0.5	-1.3	-0.9
Lung cancer (father)	2.9	3.4	9.5	-2.0	-3.0	-2.5	0.5	-3.1	-0.2	-1.8	-1.2	-0.5	-0.6
Verbal and Numeric Reasoning (VNR)	2.7	6.4	19.7	2.6	3.1	2.3	0.5	3.2	-0.2	4.4	2.2	2.1	1.9
Intelligence (Savage-Jansen 2018)	2.4	7.4	26.6	2.4	2.6	2.5	0.5	3.3	-0.4	5.2	2.3	1.8	3.0
Fluid intelligence score	2.4	4.9	15.8	1.8	3.0	2.1	0.7	2.8	-0.3	4.0	1.4	1.8	1.9
Illnesses of father: None of the above (group 1)	2.4	3.0	9.9	-2.0	-3.2	-2.8	1.5	-2.4	0.5	0.0	-0.3	-0.0	-0.7
Systolic Blood Pressure	2.3	11.4	25.3	3.2	3.9	4.1	-3.2	3.0	0.1	1.9	5.0	-2.9	-3.8
Prostate Cancer	2.2	3.1	6.1	2.4	1.6	2.4	2.2	2.5	0.1	1.5	0.7	-1.9	0.0
Vitamin and mineral supplements	2.2	3.0	7.4	-2.2	-2.5	-2.6	-1.5	-2.7	-0.1	-1.1	1.2	-0.2	-0.4
Prospective memory result	2.2	2.7	10.8	0.7	-0.3	-0.8	-1.3	-0.2	1.0	-3.3	-1.9	-1.4	-2.6
Chest pain or discomfort	2.2	3.2	9.1	1.5	3.0	1.1	2.0	1.4	-1.4	2.4	2.2	-0.8	-0.8
Chronotype (morning person)	2.1	4.8	9.9	-1.5	-2.3	-3.0	2.8	-2.0	1.1	-2.0	-1.4	-1.8	-3.1
Illnesses of siblings	2.1	2.9	6.0	-1.1	-2.0	-2.4	1.2	-1.9	-0.1	-2.4	-2.3	1.2	0.5
Medication: Aspirin	2.1	2.8	6.6	2.1	2.3	2.6	0.8	1.7	-0.6	1.0	1.2	-1.3	-1.9
Bipolar Disorder (2018)	2.0	3.1	9.9	2.6	2.0	3.1	0.6	2.9	1.3	0.3	-0.0	0.1	0.1
Diabetes (father)	2.0	2.5	5.6	-2.0	-2.4	-1.3	1.7	-2.0	1.5	-0.1	-0.9	1.3	1.4
Had menopause	2.0	2.5	6.5	2.5	1.7	2.2	-0.7	2.4	-1.3	-0.3	-0.1	1.4	1.0
Impedance of arm (left)	2.0	9.2	19.2	3.8	4.1	4.2	1.3	4.4	-1.5	3.0	2.1	-2.3	1.5
Medication: Gliclazide	2.0	2.3	7.3	-2.2	-1.9	-2.1	0.7	-2.7	-1.3	-0.2	-0.7	0.3	0.5
Coronary Artery Disease (CAD)	1.9	2.3	6.7	1.4	1.8	2.6	1.2	2.0	0.9	1.0	1.3	-1.3	0.4
Medication: Metformin	1.9	2.7	5.7	-2.4	-1.7	-2.1	1.5	-2.3	-0.9	0.4	-1.1	0.6	-1.9
Impedance of arm (right)	1.9	9.0	17.2	3.8	4.1	3.9	1.9	4.1	-0.8	3.0	2.5	-1.6	2.0
Migraine (self-reported)	1.9	2.4	5.3	-2.3	-0.9	-2.3	2.3	-1.7	0.8	0.6	-0.5	-1.0	-1.5
Age at First Birth	1.8	2.6	7.6	2.8	1.2	1.9	-0.6	2.4	0.3	0.4	0.6	-2.1	-1.5
Type 2 Diabetes (T2D) (2018)	1.8	3.3	8.6	-2.9	-1.9	-2.5	0.8	-2.9	-0.5	-0.5	-1.1	-0.1	-1.8
Systolic blood pressure, automated reading	1.8	5.1	10.4	2.3	2.6	3.0	-3.2	2.2	0.1	1.6	2.2	-1.9	-1.9
Multivitamins +/- minerals	1.8	2.3	6.9	2.0	2.1	2.1	1.3	2.6	-0.2	0.3	-1.0	-0.5	0.1
Hair/balding pattern: Pattern 2	1.8	2.3	12.0	1.3	1.2	1.0	0.9	1.6	-1.2	1.4	0.3	-3.5	-0.2
Qualifications: None of the above	1.8	3.9	10.6	-1.2	-1.9	-1.5	-2.7	-2.1	-1.4	-1.9	0.2	-2.0	-3.3
Chronic bronchitis/emphysema (mother)	1.8	2.0	8.9	0.1	0.9	0.5	-2.0	0.2	0.1	2.4	3.0	0.4	0.5
Alcohol usually taken with meals	1.7	2.7	7.4	1.9	2.7	1.7	0.9	2.7	-0.8	1.2	0.4	-0.2	1.6
High blood pressure (siblings)	1.7	2.4	6.1	0.7	1.4	1.5	-0.9	1.2	-0.4	2.5	2.3	-2.3	-0.7
Ovarian Cancer	1.6	2.1	6.4	0.2	-0.5	1.0	-2.3	0.5	1.6	2.5	-0.5	-0.9	1.9
LDL Cholesterol	1.6	2.6	12.1	-0.2	1.0	0.2	0.7	0.5	-2.8	3.5	1.8	-0.4	0.2
Average weekly spirits intake	1.6	2.0	6.1	-2.2	-1.1	-2.5	0.1	-2.1	0.0	-0.4	-0.9	1.6	-0.2
Medication: Ramipril	1.6	2.1	4.1	1.4	1.6	2.0	0.5	1.9	-0.3	0.3	2.0	-1.7	-1.0
Qualifications: NVQ or HND or HNC or equivalent	1.6	1.9	5.2	-1.4	-1.8	-2.0	1.1	-2.3	0.8	-1.1	-1.1	-0.2	-0.5
Impedance of whole body	1.6	8.0	17.7	3.2	3.4	4.2	1.1	3.8	-0.8	3.0	1.9	-2.9	1.7
Waist Hip Ratio (WHR)	1.5	6.9	18.1	-4.2	-3.8	-3.7	1.8	-3.6	-0.1	0.6	-2.3	1.0	-0.3
Financial difficulties in last 2 years	1.5	2.0	5.9	-1.5	-1.0	-2.4	1.1	-1.8	1.1	-0.5	1.7	-0.2	-1.3
Mineral and other dietary supplements	1.5	2.1	6.5	-1.6	-2.0	-1.6	1.3	-2.5	-0.8	0.1	-0.2	-1.6	0.1
Medication: Aspirin	1.5	2.0	5.2	1.6	1.6	2.0	0.4	1.3	-0.4	1.3	0.8	-1.2	-2.3
Average weekly beer plus cider intake	1.5	2.1	5.0	-1.8	-2.2	-1.3	-1.5	-1.7	0.7	-1.2	-2.0	-0.2	-0.4
Supplements: Glucosamine	1.4	1.9	4.5	1.6	1.9	1.3	-0.3	2.1	0.8	1.0	0.2	1.6	1.4
Heart attack	1.4	1.8	4.8	1.3	1.8	1.7	-0.2	1.3	-0.6	1.4	2.2	0.9	0.9
Pain all over the body in last month	1.4	1.5	6.2	-1.2	-0.6	-1.1	2.5	-1.0	0.9	-0.6	-1.3	0.8	0.7
Age started oral contraceptive pill	1.4	1.8	4.5	2.1	1.7	1.4	-1.0	1.5	-1.6	-0.1	1.1	-0.6	0.9
Blood Platelet Count	1.3	14.7	82.4	-2.6	-1.9	-2.4	3.7	-2.2	9.1	-3.0	-3.1	0.1	-3.4
Taking other prescription medications	1.3	2.0	4.6	2.1	2.1	1.5	-0.7	1.7	-0.7	0.7	1.8	-0.0	-1.0
Medication: Lansoprazole	1.3	1.4	3.8	-1.1	-1.2	-1.4	-0.2	-1.9	1.0	-1.6	-0.9	1.1	0.1
Comparative body size at age 10	1.3	3.6	19.6	-0.4	-0.5	-1.1	-0.5	-0.2	2.3	-2.4	-0.0	-1.8	-4.4
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.3	1.6	5.1	1.4	2.2	1.7	0.8	1.6	-0.1	0.2	-0.2	-1.6	-0.4
Breast cancer (self-reported)	1.3	1.6	4.6	2.1	1.6	1.1	-0.2	1.6	-0.1	-1.4	-0.5	0.7	-1.4
Number of self-reported non-cancer illnesses	1.3	2.2	5.8	0.9	1.4	1.4	0.3	0.4	-0.8	2.0	2.4	-2.0	-1.7
Financial situation satisfaction	1.3	1.6	4.1	2.0	0.9	0.5	0.6	1.1	-0.4	-0.5	1.9	-1.5	-1.7
Vascular/heart problems diagnosed by doctor	1.3	3.6	9.6	-0.9	-2.6	-1.9	0.5	-0.9	-0.3	-2.0	-3.1	2.0	2.6
Heart attack/myocardial infarction (self-reported)	1.3	1.7	4.9	1.3	1.7	1.6	-0.1	1.2	-0.6	1.3	2.2	0.8	0.7
Number of treatments/medications taken	1.2	2.1	5.1	2.3	2.2	1.7	0.5	1.6	0.4	-0.4	0.7	-0.4	-2.0
Supplements: Zinc	1.2	1.3	7.7	-0.3	1.1	0.0	0.7	0.5	-2.8	1.6	1.0	0.3	0.1
Trunk fat percentage	1.2	4.8	14.1	2.5	2.5	1.2	2.0	1.7	0.9	1.0	1.3	-3.8	-3.0
Average weekly fortified wine intake	1.2	1.4	2.1	0.5	1.4	1.3	0.8	1.1	-1.3	1.5	0.9	-1.1	1.4
Number of incorrect matches in round	1.2	2.0	5.2	-1.2	-1.7	-1.2	-2.3	-1.1	1.3	-1.3	-0.6	-0.0	-2.0
Pulse wave Arterial Stiffness index	1.2	1.4	5.8	-0.8	-1.1	-1.4	1.2	-1.2	1.1	-0.1	-0.8	-0.1	-2.4
Headache pain in last month	1.2	2.0	8.4	1.2	0.2	0.4	2.9	1.2	-1.8	0.4	-1.2	-2.1	-0.0
Pulse wave peak to peak time	1.2	1.4	5.0	0.9	1.2	1.4	-1.0	1.2	-1.1	0.4	0.8	0.2	2.2
Health satisfaction	1.2	1.6	4.8	1.7	0.7	0.7	1.8	1.5	-0.2	0.8	-0.0	-1.0	-2.2
Mouth/teeth dental problems: Loose teeth	1.2	1.4	5.6	-0.4	0.0	0.0	-1.9	-0.6	-1.5	-0.2	1.2	2.4	-1.1
Commuting to job workplace: Car/motor vehicle	1.2	1.4	5.8	-1.6	-0.7	-1.0	0.9	-1.1	0.2	-1.0	-2.4	-0.4	0.4
Loneliness, isolation	1.2	1.7	4.5	-1.7	-0.5	-2.1	2.1	-1.9	-0.5	0.1	-0.7	-0.7	0.3
Medication for cholesterol	1.2	1.8	5.2	-0.8	-1.4	-1.3	-1.2	-0.6	-1.7	-0.9	-0.7	1.5	2.3
Wears glasses or contact lenses	1.2	1.4	4.8	2.1	1.0	1.0	0.6	2.2	1.3	-0.3	-0.5	0.1	0.1
Supplements: Fish oil (including cod liver oil)	1.2	1.5	3.7	1.4	1.7	1.4	-0.8	1.9	0.1	-0.5	0.6	0.3	-1.8
Mean Putamen Volume	1.1	1.2	6.3	-0.9	-0.1	-0.8	1.0	-0.5	0.2	-0.6	-1.0	1.3	2.5
Cardiovascular Disease	1.1	3.7	13.7	0.5	1.1	1.1	0.4	0.3	1.8	0.3	1.9	-3.6	-3.7
Serious illness, injury or assault to yourself	1.1	1.3	4.5	0.3	0.8	1.2	-1.3	0.7	-1.2	1.6	2.1	0.2	0.5
Breastfed as a baby	1.1	1.3	4.1	-1.3	0.0	-0.9	1.2	-1.1	-2.0	1.0	1.1	1.3	0.3
Wheeze or whistling in the chest in last year	1.1	2.0	4.9	2.1	2.2	1.6	1.2	1.4	-1.1	1.2	1.4	0.3	-0.7
Reason for reducing amount of alcohol drunk: Health precaution	1.1	1.2	3.2	1.4	0.7	1.8	0.2	1.0	-1.8	-0.7	-1.0	0.8	0.8
Had major operations	1.1	1.3	4.9	0.6	1.4	0.1	-0.2	0.7	-1.2	2.2	1.2	1.2	1.0
Supplements: Vitamin C	1.1	1.3	3.1	0.5	1.3	1.5	1.8	1.0	-1.1	-0.1	-1.2	-1.3	-0.5
Illnesses of siblings: Diabetes	1.1	1.3	3.7	-1.1	-0.8	-1.0	-0.0	-0.9	1.9	0.8	0.3	1.4	-1.8
Commuting to job workplace: Walk	1.1	1.2	4.3	0.7	1.4	1.5	-0.9	1.0	0.4	0.8	2.1	0.7	0.7
Osteoarthritis (self-reported)	1.1	1.5	6.8	0.6	1.2	-0.6	1.1	-0.0	2.1	-0.3	0.1	0.6	-2.6
Medication: Lisinopril	1.1	1.5	4.2	-1.7	-0.9	-1.2	-0.6	-2.1	0.9	1.1	1.6	0.4	0.5
Medication: Atorvastatin	1.1	1.3	4.1	-1.4	-0.7	-0.0	-0.2	-0.3	0.9	2.0	1.6	1.4	-0.9
Risk taking	1.1	1.6	7.2	-0.6	-0.3	-0.4	0.1	-0.5	-1.7	1.4	2.7	0.3	1.7
Myopia	1.1	1.6	4.8	-1.2	-1.1	-0.8	2.2	0.1	0.5	0.7	-1.9	-1.0	-1.5
Worry (Nagel 2018)	1.0	2.1	5.8	1.2	-0.7	1.3	1.3	1.1	0.8	-1.5	-1.4	-1.9	-2.4
Ulcerative Colitis (UC)	1.0	1.8	5.7	-1.0	-0.4	-2.4	0.3	-2.0	0.9	-1.0	1.1	1.8	-1.0
Fasting Glucose	1.0	1.2	8.0	-0.2	0.3	-0.0	2.8	-0.1	-0.0	-0.6	-0.7	-1.6	-0.2
Smoking Status	1.0	2.3	6.7	-1.5	-2.6	-2.3	-0.4	-1.9	-0.3	-1.7	-1.1	0.7	-0.0
Allergy or Eczema	1.0	2.7	7.3	1.4	1.3	1.1	2.2	1.3	-2.7	0.9	0.1	-1.2	-2.4
Other serious medical condition/disability diagnosed by doctor	1.0	1.3	6.2	-0.0	1.4	0.4	2.5	0.1	-1.1	1.7	0.7	0.4	0.2
Ever used hormone-replacement therapy (HRT)	1.0	1.3	3.7	1.4	0.6	1.9	-1.9	1.0	-1.1	-0.7	0.3	-0.1	0.8
Medication for hormone replacement therapy	1.0	1.1	2.7	1.4	1.1	1.5	-0.4	1.6	0.6	1.0	-0.8	0.4	0.6
Diabetes (mother)	1.0	1.3	4.1	-1.6	-1.5	-1.3	-0.0	-2.0	-0.0	0.2	-0.6	1.3	-0.7
Pack years adult smoking proportion	1.0	1.5	4.9	-1.0	-1.8	-2.2	0.8	-1.4	-1.0	0.1	-0.8	-1.0	-0.4
High blood pressure	1.0	2.8	6.4	0.2	1.7	1.4	-0.7	0.5	1.1	1.9	2.2	-2.5	-2.5
Medication: Atenolol	1.0	1.3	5.8	-0.2	0.2	0.2	-0.4	-0.8	0.0	-1.5	1.7	-1.0	-2.4
Impedance of leg (left)	1.0	5.0	11.7	2.2	2.3	3.4	0.6	2.7	0.1	2.6	1.8	-2.7	1.8
Number of live births	1.0	1.5	4.3	-0.7	-1.2	-1.1	0.9	-1.2	-1.5	-1.5	-0.5	-0.4	2.1
Illnesses of mother	1.0	1.2	6.0	0.1	-1.0	-0.4	-0.4	0.2	-0.8	-0.8	-1.4	-1.2	2.4
Hair/balding pattern: Pattern 4	1.0	2.5	13.8	-0.2	-1.0	-1.0	0.2	-0.4	-0.7	-1.9	-2.1	0.6	-3.7
Body fat percentage	1.0	4.0	11.8	2.4	2.1	0.9	1.6	1.6	1.1	1.1	1.4	-3.4	-2.8
Qualifications: College or University degree	1.0	3.3	7.1	1.6	2.1	2.4	0.9	2.3	-0.1	1.8	1.3	1.4	2.7
Heart disease (mother)	1.0	1.2	8.5	0.9	0.6	0.7	-0.6	0.7	0.4	-0.2	-0.1	0.8	-2.9
Alcohol intake frequency.	1.0	2.3	15.0	0.6	0.3	0.1	1.1	0.5	-0.6	-0.3	1.3	-3.9	-1.8
Miserableness	1.0	1.7	6.7	0.8	0.8	0.7	0.3	0.7	0.5	1.9	1.5	-2.6	-1.5
Ever taken oral contraceptive pill	1.0	1.1	2.5	-1.2	-1.6	-1.5	-0.4	-1.3	1.2	-0.5	-0.7	-0.1	0.7
Irritable Bowel Disease (IBD)	0.9	2.2	5.4	-1.2	-0.2	-2.3	0.0	-2.1	0.4	-1.1	0.8	2.3	-1.8
Frequency of depressed mood in last 2 weeks	0.9	1.2	6.8	-0.4	-1.1	-1.2	-0.1	-0.7	0.7	-1.0	-0.3	-2.6	0.7
Medication: Simvastatin	0.9	1.3	4.3	1.4	1.2	2.1	0.6	0.8	1.2	-1.4	0.7	-0.7	0.6
Trunk predicted mass	0.9	4.9	13.6	-2.2	-2.3	-3.7	0.7	-2.9	0.8	-1.4	0.2	2.1	-3.2
Exposure to tobacco smoke at home	0.9	1.0	4.6	-0.8	-1.2	-0.8	-2.2	-0.9	0.8	0.5	0.2	0.1	-1.1
Number of children fathered	0.9	1.0	3.7	0.4	0.0	0.0	-1.2	-0.6	0.0	-1.9	-0.4	1.4	-1.5
Age at first live birth	0.9	1.5	6.2	0.2	0.9	0.4	-0.6	1.4	1.8	0.8	-0.5	2.5	1.3
Shortness of breath walking on level ground	0.9	1.1	2.1	1.2	1.2	1.5	0.5	0.6	-1.0	0.6	1.4	-0.9	-0.9
Eye problems/disorders: None of the above	0.9	1.1	4.1	1.4	1.1	2.0	0.7	1.3	-0.4	-0.2	0.3	-0.7	-0.7
Arm predicted mass (right)	0.9	4.5	18.2	-2.2	-1.9	-3.1	0.5	-2.5	0.9	-1.1	-0.1	0.6	-4.3
Diabetes diagnosed by doctor	0.9	1.5	4.8	-1.9	-1.6	-1.8	0.4	-2.2	-0.3	0.1	-0.7	0.2	-0.7
Medication: Blood pressure	0.9	1.6	4.6	-0.6	0.2	-0.5	1.4	-0.6	1.1	1.3	1.4	-2.0	-2.1
Commuting to job workplace: Cycle	0.9	1.0	3.1	0.2	0.2	0.6	-0.8	0.9	1.7	0.4	-0.9	1.3	1.8
Supplements: Calcium	0.9	1.0	3.1	0.9	1.1	0.9	0.1	1.8	0.8	0.9	-0.8	1.2	-0.8
Pack years of smoking	0.9	1.3	4.2	-1.0	-1.9	-2.0	1.0	-1.4	-0.5	-0.1	-0.9	-0.6	-0.2
BMI	0.8	4.4	13.1	-2.1	-1.9	-3.0	0.0	-2.6	1.7	-1.2	0.6	-1.7	-3.6
Hypothyroidism (self reported)	0.8	1.8	4.8	0.9	-0.6	0.4	-1.9	-0.3	-0.7	1.0	1.9	-2.2	-1.6
Eye problems/disorders: Diabetes related eye disease	0.8	0.9	2.4	-0.7	-0.4	-0.6	1.6	-0.5	0.9	1.4	-0.1	-0.9	-1.1
Current tobacco smoking	0.8	1.3	3.3	-0.8	-1.8	-1.1	-0.0	-1.7	-1.0	0.6	-0.8	-0.8	1.4
Relative age voice broke	0.8	1.2	3.9	0.2	0.5	0.7	1.1	1.1	0.9	1.8	-0.1	0.9	2.0
Sitting height	0.8	5.4	13.0	3.6	2.8	2.7	0.2	3.4	-1.1	1.3	2.6	-0.5	-2.2
Trunk fat mass	0.8	3.4	12.7	1.7	1.6	0.1	2.0	0.9	0.9	0.7	1.1	-2.9	-3.6
Mouth/teeth dental problems	0.8	1.2	3.4	1.5	1.3	1.0	-0.2	1.9	0.9	-0.2	-0.7	-0.9	1.5
Trunk fat-free mass	0.8	4.7	12.8	-2.1	-2.2	-3.6	0.7	-2.8	0.8	-1.3	0.2	2.1	-3.2
Time employed in main current job	0.8	0.9	3.1	0.8	1.3	1.2	0.2	1.8	0.4	-0.3	-1.1	-0.2	0.6
Qualifications: A levels/AS levels or equivalent	0.8	1.9	4.0	1.3	1.3	1.0	0.9	1.8	-0.6	2.0	1.1	0.8	2.0
Medication: Cholesterol lowering	0.8	1.2	4.5	1.1	1.4	2.1	0.2	0.4	-0.2	-1.1	1.2	1.0	-0.6
Length of working week for main job	0.8	0.9	2.7	0.7	-1.0	-0.3	-1.3	-0.5	-0.5	-1.0	0.2	-1.6	-1.2
Ever highly irritable/argumentative for 2 days	0.8	0.9	2.2	-1.2	0.3	-1.5	1.1	-1.2	-1.1	0.0	0.8	1.0	-0.2
Loud music exposure frequency	0.8	0.9	3.9	0.9	0.4	0.9	-2.0	0.8	-1.3	-0.2	-0.8	0.6	-0.5
Glaucoma (self-reported)	0.8	0.9	5.1	-0.4	0.5	0.1	-1.3	0.1	1.4	0.4	2.3	0.3	0.3
Arm fat-free mass (right)	0.8	4.2	17.6	-2.0	-1.7	-3.0	0.4	-2.4	0.7	-1.0	-0.1	0.4	-4.2
Family relationship satisfaction	0.8	0.9	4.5	0.4	-0.2	-0.4	2.1	-0.1	-1.6	0.1	-1.1	0.4	-0.7
Knee pain experienced in last month	0.8	1.2	4.4	0.9	0.8	-0.5	0.4	-0.0	2.1	-0.6	-1.3	0.4	-1.9
Whole body fat-free mass	0.8	4.6	15.8	-1.8	-1.9	-3.5	1.1	-2.6	0.7	-1.1	0.2	1.4	-4.0
Mouth/teeth dental problems: Mouth ulcers	0.8	1.2	3.7	1.7	0.6	1.9	0.3	1.2	0.2	-0.1	-0.3	-1.9	0.0
Smoking status: Current	0.8	1.3	3.7	-0.8	-1.9	-1.2	0.4	-1.6	-0.7	0.7	-0.7	-0.6	1.5
Whole body water mass	0.8	4.3	15.9	-1.7	-1.7	-3.3	1.1	-2.4	0.7	-1.1	0.2	1.3	-4.0
Illnesses of father: High blood pressure	0.8	0.9	3.3	0.9	1.4	1.8	0.1	1.0	0.2	-0.1	0.5	-1.0	1.0
Ever had prostate specific antigen (PSA) test	0.8	0.9	3.0	1.2	1.2	0.6	1.7	1.1	-0.6	-0.1	-0.7	0.8	-0.4
Cholesterol lowering medication	0.8	1.1	3.6	-0.7	-0.4	0.2	1.1	-0.3	1.9	-0.9	0.1	-1.7	-1.2
Heart disease (siblings)	0.8	1.0	2.0	0.6	1.0	1.3	-0.6	1.2	0.1	1.1	1.4	1.1	-0.9
Depression (Nagel 2018)	0.7	1.0	4.8	0.5	-0.5	-0.0	0.9	0.1	1.3	-0.5	1.4	-2.2	0.3
Alzheimer’s Disease (in mother)	0.7	0.8	4.4	-0.3	-0.0	-0.4	0.9	1.0	0.4	2.1	-0.6	-0.5	-1.0
Major Depression (MDD)	0.7	0.9	5.9	-0.1	-0.5	0.2	-2.4	0.1	-0.5	-0.1	0.9	-1.2	-0.4
Lupus	0.7	1.0	3.1	-0.7	-0.3	-1.2	-1.3	-1.0	0.1	-1.8	0.5	-0.9	-1.2
Heel T-Score	0.7	5.3	13.6	-2.8	-2.9	-1.6	-0.3	-3.7	-1.5	-1.5	-3.6	-0.1	1.5
Lung FVC	0.7	3.7	18.2	-1.8	-0.9	-2.1	1.8	-1.9	1.5	0.2	0.6	4.3	1.2
Hand grip strength (left)	0.7	1.9	4.7	-1.6	-2.2	-1.1	-0.1	-1.7	-0.2	-0.8	-1.8	0.9	-1.6
Hearing difficulty/problems: Yes	0.7	1.1	2.8	1.6	0.8	1.3	-1.4	1.7	0.2	0.7	0.8	-0.1	-0.2
Ever had hysterectomy (womb removed)	0.7	0.8	5.9	0.1	0.8	0.5	0.5	0.1	-0.3	-0.4	-0.7	2.4	-0.5
Medication: Co-codamol	0.7	0.8	2.1	1.5	1.1	1.3	0.1	0.8	-0.7	0.9	0.8	-0.2	-0.8
Leg fat-free mass (left)	0.7	3.7	20.2	-1.0	-1.1	-2.8	1.6	-1.8	0.4	-0.8	0.2	0.6	-4.5
Maternal smoking around birth	0.7	1.0	2.1	-1.4	-0.7	-1.3	-0.7	-0.7	-1.4	0.5	-0.5	-0.3	-1.4
Stomach or abdominal pain in last month	0.7	0.9	2.3	1.1	0.3	0.8	-0.7	1.0	0.2	1.1	-1.3	-1.5	-0.6
Chronic bronchitis/emphysema (father)	0.7	0.8	3.7	0.0	0.4	0.5	-1.9	0.2	1.1	0.0	-1.4	-0.2	-0.8
Leg predicted mass (left)	0.7	3.9	21.0	-1.1	-1.2	-2.9	1.4	-1.8	0.5	-0.8	0.3	0.6	-4.6
Waist circumference	0.7	2.7	13.1	-0.7	-1.0	-2.5	1.6	-1.5	0.8	-0.2	0.2	-0.9	-3.6
Hearing difficulty/problems with background noise	0.7	1.1	4.0	0.5	0.6	0.5	-0.4	1.4	-0.4	0.4	1.0	-1.8	-2.0
Depression (self-reported)	0.7	0.8	4.0	0.3	0.3	0.6	0.6	-0.0	0.6	-0.2	1.2	-2.0	-1.2
Seen doctor (GP) for nerves, anxiety, tension or depression	0.7	1.0	7.3	0.6	-0.5	0.6	-0.1	0.5	0.5	0.1	-0.5	-2.7	1.0
Pulse wave reflection index	0.7	0.8	2.0	-1.3	-1.0	-1.1	1.4	-1.0	-0.7	0.4	0.1	0.6	0.6
Gout (self-reported)	0.7	0.9	4.4	-0.3	-0.2	-0.1	-0.4	-0.4	0.6	-0.7	-0.1	1.8	2.1
Hypothyroidism/myxoedema (self-reported)	0.7	1.3	3.6	1.3	-0.4	0.9	-1.9	0.2	-0.8	0.8	1.1	-1.7	-1.4
Whole body fat mass	0.7	2.9	11.9	1.7	1.4	0.0	1.7	0.8	1.2	0.7	1.1	-2.3	-3.4
Suffer from ‘nerves’	0.7	1.1	4.9	0.5	-0.7	1.0	0.3	0.7	1.2	-0.8	-0.1	-2.2	-1.2
Age at last live birth	0.7	1.1	3.1	0.7	1.1	0.9	0.7	1.4	0.4	0.8	-0.2	1.4	1.8
Illness, injury, bereavement, stress in last 2 years	0.7	0.8	3.5	0.2	-1.1	-0.4	-0.7	0.0	0.5	-1.3	-1.9	0.4	0.7
Hypertension (Self-reported)	0.7	2.0	5.4	0.1	1.5	1.3	-0.1	0.1	0.8	1.6	1.6	-2.3	-2.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.7	0.9	2.7	-1.0	-1.2	-1.1	0.7	-0.6	1.6	-1.1	-0.5	0.5	0.0
Leg fat-free mass (right)	0.7	3.7	22.8	-0.9	-0.8	-2.7	1.6	-1.6	0.4	-0.7	0.3	0.2	-4.8
Back pain experienced in last month	0.7	1.1	4.2	-0.8	0.2	-1.2	0.4	-1.4	0.8	-0.3	1.3	0.5	-2.1
Leg predicted mass (right)	0.7	3.7	21.8	-0.9	-0.9	-2.8	1.6	-1.6	0.4	-0.7	0.2	0.1	-4.7
Hearing aid user	0.7	0.8	3.2	-0.1	-0.3	0.3	-0.3	0.2	0.8	1.4	1.1	0.0	1.8
Tinnitus: Yes, now most or all of the time	0.7	0.8	3.1	0.5	0.8	0.4	-1.0	1.0	-1.3	1.8	0.4	0.0	-0.5
High cholesterol (Self-reported)	0.7	1.2	5.6	1.2	0.3	1.5	0.5	0.7	1.3	-2.4	0.0	-0.2	-0.3
Basal metabolic rate	0.7	4.1	17.1	-1.5	-1.5	-3.2	1.3	-2.2	1.0	-0.8	0.3	0.7	-4.1
Arm fat-free mass (left)	0.7	3.8	12.7	-1.7	-1.5	-3.1	0.8	-2.4	1.6	-0.7	0.4	0.9	-3.6
Alcohol drinker status: Previous	0.7	0.8	4.9	0.2	0.0	0.1	0.7	0.4	0.3	-1.2	-0.6	-2.2	-0.9
Arm predicted mass (left)	0.7	3.6	12.0	-1.6	-1.6	-3.0	0.5	-2.4	1.3	-0.9	0.5	1.1	-3.5
Schizophrenia vs Biploar Disorder	0.6	0.8	2.2	-0.4	-1.1	-1.4	-0.9	-1.2	-1.5	-0.3	-0.2	-0.3	0.1
Alzheimer’s Disease (in father)	0.6	0.7	4.2	-0.9	0.0	-0.2	-0.8	-0.5	0.5	-0.1	0.9	2.1	0.3
Body Mass Index (BMI) (2010)	0.6	0.9	1.9	-1.2	-0.5	-1.3	1.1	-1.2	-0.0	-1.4	0.4	-0.2	-0.7
HbA1C	0.6	0.6	2.1	-0.7	-0.8	-0.6	0.8	-0.4	-1.5	0.3	-0.9	-0.9	-0.4
Triglycerides	0.6	0.9	2.3	-1.2	1.0	-0.9	0.4	-1.5	0.1	0.7	1.3	0.2	-1.1
Sensitivity / hurt feelings	0.6	1.1	3.9	-0.8	-0.9	-1.1	0.5	-0.6	0.5	0.2	-0.4	-2.0	-1.9
Relative age of first facial hair	0.6	1.2	2.6	1.4	1.3	1.6	0.0	1.1	0.5	1.6	0.8	0.1	0.9
Impedance of leg (right)	0.6	2.9	7.1	1.4	1.5	2.7	0.5	2.0	0.2	2.0	1.3	-1.4	2.4
Hand grip strength (right)	0.6	1.6	4.2	-0.1	-1.7	-0.2	0.0	-0.5	1.5	-1.5	-1.9	0.8	-2.0
Frequency of unenthusiasm / disinterest in last 2 weeks	0.6	0.8	2.4	0.9	0.4	0.5	1.0	0.5	0.2	0.5	1.6	-1.5	-0.3
Qualifications: CSEs or equivalent	0.6	0.8	3.8	-0.9	-1.9	-0.6	-0.8	-0.9	-0.3	-0.8	-0.4	-1.1	0.0
Hayfever, allergic rhinitis or eczema	0.6	1.4	4.5	0.8	0.6	0.3	2.1	0.5	-1.7	0.1	0.4	-0.7	-2.1
Diabetes (self-reported)	0.6	1.0	2.2	-1.4	-1.0	-1.3	0.4	-1.5	0.3	0.4	-0.8	1.3	0.4
Neuroticism score	0.6	1.3	4.8	0.7	0.1	0.7	2.1	0.9	-0.3	0.2	-0.3	-2.2	-1.2
Weight	0.6	2.8	16.8	-0.0	-0.2	-2.0	1.8	-0.9	1.2	-0.1	0.7	-1.0	-4.1
Hip circumference	0.6	2.4	8.3	2.0	1.9	0.1	1.1	1.1	1.3	0.1	1.5	-1.3	-2.9
Father’s age at death	0.6	0.8	3.0	0.7	0.9	1.0	-0.4	1.1	0.3	0.6	0.7	0.7	1.7
Serious illness, injury or assault of a close relative in last 2 years	0.6	0.7	1.6	0.3	1.2	0.7	0.4	0.3	-1.1	1.0	0.9	0.0	-1.1
Tense / ‘highly strung’	0.6	1.0	2.5	1.2	0.5	0.8	1.0	1.2	-0.3	-0.5	-1.6	-1.0	-0.9
Birth weight of first child	0.6	1.0	3.3	-0.7	-0.5	-1.8	1.8	-1.0	-0.6	-1.2	-0.3	-0.4	-0.2
Medication for cholesterol, blood pressure or diabetes	0.6	0.9	3.2	-1.1	-1.3	-1.8	0.1	-0.8	-0.1	0.5	-0.8	-0.5	1.2
Exposure to tobacco smoke outside home	0.6	0.9	4.6	-0.2	0.1	-0.2	1.1	-0.6	0.1	-1.4	0.5	0.4	-2.1
Seen a psychiatrist for nerves, anxiety, tension or depression	0.6	0.8	2.2	1.0	1.3	1.5	-0.1	0.8	0.4	1.0	0.3	-1.2	0.2
Emphysema/chronic bronchitis	0.6	0.6	3.0	-0.5	0.4	-0.4	0.9	-0.2	-0.2	1.4	-0.1	0.1	1.7
Neck or shoulder pain in last month	0.6	0.9	4.5	0.7	0.9	0.6	0.4	0.2	-1.1	-0.0	0.5	-2.1	-0.9
Leg pain on walking	0.6	0.8	4.3	0.7	0.1	-0.1	-0.5	-0.2	1.0	-2.1	-0.5	-0.8	-0.8
Smoking status: Previous	0.6	0.9	3.2	-0.5	-0.4	-0.6	-1.1	-0.1	0.6	-1.5	0.1	1.0	-1.8
Handedness (chirality/laterality): Left-handed	0.6	0.8	2.3	-0.3	0.3	-0.1	0.2	-0.2	-0.9	-1.1	-1.3	1.5	1.3
Ever had stillbirth, spontaneous miscarriage or termination	0.6	0.6	2.3	0.3	1.0	0.2	0.1	0.5	-1.5	1.4	-0.3	0.7	-0.1
Asthma (self-reported)	0.6	1.3	2.6	1.4	1.6	1.3	0.8	1.1	-0.3	1.4	1.3	-0.9	-0.3
Average weekly champagne plus white wine intake	0.6	0.8	2.5	-0.4	1.1	-0.3	1.4	-0.1	0.4	-1.6	-0.4	1.2	0.5
Pain type(s) experienced in last month: Hip pain	0.6	0.7	3.8	-0.3	-0.4	-0.6	-1.9	-0.7	0.6	-0.5	-0.0	-1.0	-0.8
Number of operations (self-reported)	0.6	0.9	2.3	-0.5	1.2	-1.1	-0.8	-0.5	-0.2	0.0	1.4	1.1	1.5
Basal cell carcinoma (self-reported)	0.6	0.7	2.0	0.5	1.0	1.3	0.5	0.5	0.5	0.0	1.0	-0.8	1.4
Leg fat mass (left)	0.6	2.2	11.0	0.8	0.4	-0.8	1.5	-0.0	1.4	0.1	0.7	-2.1	-3.3
Bipolar Disorder or Schizophrenia	0.5	1.2	4.2	2.0	0.7	1.9	-0.9	1.3	0.0	0.1	-0.4	0.5	0.8
Neuroticism (Nagel 2018)	0.5	1.2	3.9	0.4	-0.5	0.1	1.7	0.1	0.3	-1.2	-0.8	-2.0	-1.6
Alzheimer’s Disease (including proxy)	0.5	0.7	3.4	-0.9	0.1	-0.5	-0.2	0.4	0.7	1.0	-0.6	1.8	-0.4
Crohns Disease (2017)	0.5	1.1	5.6	-0.3	0.6	-0.8	-0.6	-0.9	0.2	-0.3	0.3	2.4	-1.6
Crohns Disease (2012)	0.5	0.7	3.1	0.1	-0.0	-0.2	-1.8	-0.2	0.3	-0.1	-0.1	1.1	-1.7
Blood Eosinophil Count	0.5	3.8	11.2	-1.8	-2.0	-2.8	0.4	-1.8	2.1	-3.4	-0.5	-1.9	-0.6
Tanning	0.5	6.5	16.3	-3.2	-3.1	-4.0	1.2	-3.3	0.1	-1.9	-1.5	3.1	0.1
Townsend deprivation index at recruitment	0.5	0.7	2.4	0.5	-0.4	-0.1	0.4	-0.5	-1.3	0.7	1.2	0.0	-1.6
Medication: Levothyroxine sodium	0.5	0.9	3.2	1.2	0.6	1.1	-0.7	0.9	-0.2	1.8	0.7	-0.6	-0.4
Body mass index (BMI)	0.5	1.9	7.7	-0.5	-0.6	-1.9	0.6	-1.3	1.4	-1.1	0.0	-1.4	-2.8
Arm fat percentage (right)	0.5	1.8	4.3	1.7	1.4	0.1	1.4	0.9	1.3	0.6	1.1	-2.1	-1.8
Falls in the last year	0.5	0.7	3.4	-0.6	1.0	-0.5	0.7	-0.3	1.8	-0.7	0.4	0.8	-0.0
Blood clot in the leg (DVT)	0.5	0.7	3.2	-0.7	-0.7	-0.7	-0.4	-0.8	-0.9	0.4	1.8	-0.5	-0.2
Medication: Amlodipine	0.5	0.7	1.9	-1.4	-0.2	-0.7	0.3	-1.2	-0.2	-0.7	0.0	-1.0	1.1
Forced vital capacity (FVC), Best measure	0.5	1.7	3.9	-0.6	-0.8	-1.2	2.0	-0.9	1.2	0.7	1.2	1.8	-1.8
Worry too long after embarrassment	0.5	0.9	6.0	-0.9	0.3	-0.1	2.5	0.0	-0.3	-0.8	-1.1	0.5	-0.1
Medication: Omeprazole	0.5	0.5	3.7	0.3	0.0	0.2	0.3	-0.6	0.4	-0.7	-0.7	-0.1	-1.9
Leg fat mass (right)	0.5	1.7	8.8	0.7	0.2	-0.9	1.4	-0.2	1.5	0.0	0.7	-1.7	-3.0
Arm fat percentage (left)	0.5	1.9	6.5	1.4	1.3	0.0	1.2	0.8	1.0	0.6	0.8	-2.6	-2.2
Average weekly red wine intake	0.5	0.8	3.6	0.5	0.2	0.5	-1.1	0.8	-0.1	1.1	1.9	0.5	0.0
Long-standing illness, disability or infirmity	0.5	0.7	2.3	1.4	1.5	1.0	-0.3	0.2	-0.9	0.7	0.6	0.1	-0.6
Ever had bowel cancer screening	0.5	0.6	3.8	-0.8	0.1	-0.5	-0.1	-0.9	-0.2	-0.8	0.4	1.9	-0.0
Eye problems/disorders: Cataract	0.5	0.6	2.2	-0.1	0.1	-0.6	-1.5	-0.3	-0.0	0.6	-1.5	0.5	0.7
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.5	0.6	2.9	-0.3	-0.7	-0.5	-0.7	-0.4	0.0	-0.1	-0.9	-1.7	-0.8
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.5	1.2	4.0	-0.6	-0.4	-1.6	1.6	-1.3	0.0	-0.3	0.3	2.0	-0.5
Guilty feelings	0.5	0.8	2.3	0.8	-0.2	0.3	1.3	0.2	1.4	-0.5	-1.5	0.6	-0.9
Mother’s age at death	0.5	0.7	3.9	0.4	-0.2	0.6	-0.1	0.3	-1.3	0.2	0.5	0.2	2.0
Eye problems/disorders: Glaucoma	0.5	0.6	2.5	-1.0	0.0	-0.8	-0.1	-0.6	1.2	0.6	1.6	0.1	-0.4
Medication: Bendroflumethiazide	0.5	0.8	3.9	-0.8	0.0	-1.0	0.6	-0.5	2.0	0.6	1.1	-0.4	-0.7
Medication: Paracetamol	0.5	0.8	3.9	-0.2	0.1	-0.4	0.0	-0.4	0.5	-0.4	-1.5	-0.8	-2.0
Leg fat percentage (left)	0.5	1.9	6.5	1.4	0.8	0.1	1.0	0.6	1.5	0.7	0.9	-2.5	-2.1
Fractured/broken bones in last 5 years	0.5	0.7	2.2	-0.1	-0.4	-0.8	-1.0	0.1	1.1	-0.8	-0.6	-0.8	1.5
Diastolic blood pressure, automated reading	0.5	1.7	6.3	0.2	1.0	1.3	-2.0	0.0	-0.7	0.9	0.9	-2.5	-1.3
Ever depressed for a whole week	0.5	0.6	3.5	-0.1	0.5	-0.1	-0.2	0.4	-0.1	0.5	1.9	0.4	1.2
Medication: Omeprazole (e.g. Zanprol)	0.5	0.6	3.1	0.6	0.4	0.2	1.3	-0.2	0.4	-0.4	-0.6	-0.4	-1.8
Pain experienced in last month	0.5	0.8	2.9	-0.3	0.1	0.9	-1.1	0.6	-0.5	0.5	0.5	1.7	1.4
Deep venous thrombosis (DVT) (self-reported)	0.5	0.7	3.1	-0.5	-0.6	-0.6	-0.3	-0.8	-0.8	1.0	1.8	-0.6	-0.3
Depressed Affect (Nagel 2018)	0.4	0.9	3.8	0.3	0.0	0.1	2.0	0.0	-0.4	0.6	0.4	-1.9	-0.4
Primary Biliary Cirrhosis	0.4	0.5	2.7	-0.2	0.3	0.3	-0.6	-0.5	0.8	-0.3	1.6	0.0	1.0
Rheumatoid Arthritis	0.4	0.5	2.1	0.4	1.4	0.4	1.2	0.2	0.4	0.3	0.4	0.6	0.8
Neuroticism	0.4	0.8	3.6	-0.3	-0.4	-0.1	1.3	-0.1	-0.8	-0.5	-0.5	-1.9	-1.3
Hair Pigment	0.4	10.2	38.4	6.2	2.9	4.3	-0.9	4.4	0.9	0.5	-1.6	-3.5	-0.1
Severe depression (siblings)	0.4	0.5	2.2	-0.2	0.0	0.6	-1.5	0.2	-0.1	-0.1	-0.3	-1.4	-0.2
Age when periods started (menarche)	0.4	0.9	4.2	-0.3	-0.6	-0.9	-0.8	-1.1	-0.3	0.0	0.0	1.1	2.0
Bilateral oophorectomy (both ovaries removed)	0.4	0.5	1.2	-0.8	-0.4	0.3	-0.2	-0.6	-0.0	-0.8	-0.9	-1.1	1.0
Heel bone mineral density (BMD) T-score, automated (left)	0.4	1.0	3.0	-0.4	-1.5	-0.2	-1.1	-1.6	-0.9	-1.7	-0.0	0.2	-0.1
Diverticular disease/diverticulitis (self-reported)	0.4	0.5	2.1	0.3	0.5	0.3	-0.6	-0.6	-0.7	1.4	1.0	-0.3	0.5
High blood pressure (mother)	0.4	0.6	1.8	-0.3	0.6	0.8	1.1	-0.1	-0.6	0.6	0.9	-0.4	-1.4
Nervous feelings	0.4	0.7	2.1	-0.1	-0.3	1.2	0.5	0.7	0.1	-1.1	-0.7	-1.5	-0.9
Frequency of tenseness / restlessness in last 2 weeks	0.4	0.6	2.0	0.1	-0.7	0.2	0.9	-0.1	1.2	-0.0	-0.1	-1.4	1.1
Had other major operations	0.4	0.5	1.5	0.2	0.2	-0.8	0.4	0.2	-1.1	0.3	1.2	-0.6	0.8
Forced vital capacity (FVC)	0.4	1.4	3.2	-0.9	-0.7	-1.2	1.7	-1.0	0.9	0.4	0.7	1.6	-1.8
Worrier / anxious feelings	0.4	0.8	2.7	0.4	-0.6	0.3	1.7	-0.1	1.0	-0.5	-0.8	-0.8	-1.6
Hair/balding pattern: Pattern 3	0.4	0.6	2.5	-0.1	0.5	-0.2	-0.4	-1.1	-0.6	0.2	0.9	1.6	-0.7
Happiness	0.4	0.5	2.0	0.9	-0.0	0.1	0.6	0.9	-1.4	-0.4	0.1	0.9	-0.0
Noisy workplace	0.4	0.5	1.6	-0.3	-1.3	-0.5	0.3	-0.7	-0.1	-1.1	-0.4	-1.3	0.0
Arm fat mass (right)	0.4	1.7	7.5	0.9	0.6	-0.7	1.4	0.1	1.6	0.1	0.6	-1.8	-2.7
Qualifications: O levels/GCSEs or equivalent	0.4	0.7	2.2	0.1	0.2	0.6	0.5	0.8	1.4	1.5	0.8	0.3	0.8
Medication: Paracetamol	0.4	0.7	3.0	0.1	0.5	-0.1	1.5	0.0	0.4	-0.5	-1.0	-0.7	-1.7
Medication: Ventolin 100micrograms inhaler	0.4	0.5	2.4	0.0	0.5	0.3	-0.1	-0.0	-1.6	0.9	0.7	-0.2	-0.6
Medication for pain relief, constipation, heartburn	0.4	0.7	3.6	-0.7	-0.7	-0.7	-0.8	0.0	-0.0	0.4	0.3	1.1	1.9
Medication: Allopurinol	0.4	0.5	1.5	0.8	0.8	0.8	-0.6	0.3	-0.6	-0.3	0.5	1.2	0.5
Friendships satisfaction	0.4	0.5	1.4	1.0	0.4	0.4	0.8	1.2	-0.9	-0.1	0.1	-0.3	-0.5
Arm fat mass (left)	0.4	1.7	8.4	0.5	0.5	-1.0	1.3	-0.2	1.4	-0.0	0.6	-1.7	-2.9
Irritability	0.4	0.6	3.2	0.1	0.4	-0.3	1.8	0.6	0.6	-0.2	-1.3	0.8	0.3
Schizophrenia (2018)	0.3	0.7	2.8	0.5	-0.8	-0.1	-1.7	-0.6	-1.2	-0.1	-0.6	0.6	0.9
Reaction Time	0.3	0.6	2.0	-0.8	-0.2	-0.9	-0.4	-0.4	0.4	0.4	0.8	1.4	1.0
Breast Cancer	0.3	0.7	3.6	-0.1	-0.4	0.4	-0.9	0.4	0.1	1.9	0.3	-0.4	-1.2
HDL Cholesterol	0.3	0.5	1.7	0.3	-0.7	0.4	-1.3	0.4	-0.7	-0.8	-0.8	-0.3	0.3
Schizophrenia (2014)	0.3	0.7	5.2	0.3	-0.2	0.1	-2.3	-0.5	-0.1	-1.0	-0.5	0.5	-0.1
Ulcerative Colitis	0.3	0.4	1.6	0.1	-0.7	-1.2	-0.1	-0.3	0.2	-1.2	0.2	-0.2	-0.1
Past tobacco smoking	0.3	0.6	2.7	0.2	0.6	0.4	0.9	-0.3	-0.5	0.9	0.4	-1.6	0.7
Allergy	0.3	0.7	2.4	-0.4	-0.3	-0.0	-1.5	-0.1	1.6	-0.8	-0.6	0.8	0.8
Hayfever/allergic rhinitis (self-reported)	0.3	0.4	1.6	0.8	0.2	0.1	0.3	-0.2	-0.9	1.2	0.4	-0.6	0.0
Alcohol intake versus 10 years previously	0.3	0.5	2.7	-0.6	-0.3	0.2	0.4	-0.7	-0.7	0.2	-0.5	-1.6	-0.3
Frequency of tiredness / lethargy in last 2 weeks	0.3	0.5	2.1	0.3	0.1	-0.2	1.4	0.0	-1.1	0.6	0.4	-0.1	1.2
Forced expiratory volume in 1-second (FEV1)	0.3	1.1	2.4	-0.8	-1.0	-1.5	1.2	-0.8	1.1	0.3	0.7	0.9	-1.5
Pulse rate	0.3	0.5	1.5	-0.6	0.2	0.6	0.1	-0.4	0.6	1.2	-1.0	-0.1	1.0
Asthma	0.3	0.7	1.3	1.0	1.1	1.0	0.6	0.8	-0.2	1.1	0.9	-0.8	-0.1
Forced expiratory volume in 1-second (FEV1), Best measure	0.3	1.1	2.7	0.1	-0.3	-0.9	1.6	0.0	1.3	0.7	1.6	1.0	-1.2
Standing height	0.3	2.6	9.3	1.2	0.9	-0.1	2.7	0.8	-0.4	1.7	1.8	0.7	-3.0
Birth weight	0.3	0.6	1.9	0.7	-0.2	0.4	0.4	1.4	0.6	0.8	0.5	-1.0	1.1
Leg fat percentage (right)	0.3	1.2	3.5	1.2	0.5	-0.2	0.9	0.3	1.6	0.5	0.7	-1.9	-1.6
Number of full brothers	0.3	0.4	1.7	-0.0	-1.3	0.1	-0.2	-0.3	0.7	0.9	-0.0	0.9	-0.5
Medication: Blood pressure	0.3	0.5	1.2	0.3	0.8	1.1	-0.5	0.5	0.6	-0.5	0.8	-0.5	-0.8
Comparative height size at age 10	0.3	1.8	11.5	-0.2	-0.3	-1.3	1.5	0.3	-0.1	1.3	0.8	0.1	-3.4
Number of full sisters	0.3	0.4	1.1	0.5	0.5	0.7	1.0	0.4	0.1	0.7	0.4	-0.9	0.4
Forced expiratory volume in 1-second (FEV1), predicted	0.3	0.7	4.9	0.9	0.5	-0.1	0.3	0.0	-0.3	0.5	2.2	-0.0	-0.7
Osteoporosis (self-reported)	0.3	0.4	1.7	0.1	0.5	-0.5	-0.9	0.0	0.4	-0.5	0.3	-0.4	-1.3
Alcohol drinker status: Never	0.3	0.3	0.7	-0.4	0.2	-0.3	0.8	-0.1	0.8	-0.7	0.9	-0.6	-0.1
Blood Red Count	0.2	1.5	4.7	-1.6	-1.5	-2.2	0.3	-1.4	-0.4	1.9	0.1	0.0	-0.4
Blood White Count	0.2	1.6	8.8	-0.9	0.2	-0.9	-0.4	-0.6	-0.5	-0.7	-1.0	-3.0	-1.9
Height	0.2	4.3	16.5	2.3	2.1	1.1	1.8	1.5	-0.5	1.6	2.6	-0.8	-4.1
Lung FEV1/FVC ratio	0.2	0.8	2.6	0.7	1.0	-0.0	-0.4	1.1	0.7	0.3	1.6	-0.8	1.2
Fed-up feelings	0.2	0.4	1.3	-0.4	-0.6	-0.3	1.1	-0.5	0.3	0.7	0.4	-0.5	1.1
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.5	2.0	0.5	-0.6	0.9	-0.2	-0.5	-0.6	-1.4	-0.5	-0.7	-0.7
Ever unenthusiastic/disinterested for a whole week	0.2	0.2	1.2	-0.5	0.2	-0.0	0.7	0.0	0.1	-0.4	0.2	-0.1	1.1
Mouth/teeth dental problems: Dentures	0.2	0.3	1.2	-0.2	-0.9	-0.5	-0.1	-1.1	0.1	-0.5	-0.2	0.1	-0.6
Peak expiratory flow (PEF)	0.2	0.6	2.9	-0.4	-0.4	-0.4	-0.1	0.3	1.1	0.3	0.8	-0.6	-1.7
Medication: Ibuprofen	0.2	0.3	0.9	-0.1	-0.1	-0.2	-1.0	-0.5	0.4	-0.4	-0.4	0.7	0.8
Medication: Seretide 50 evohaler	0.2	0.3	0.9	0.7	-0.3	0.2	-0.5	-0.0	0.4	0.2	0.5	-0.8	-0.9
Pulse rate, automated reading	0.2	0.8	2.8	-0.2	-0.0	-0.7	1.7	-0.9	-1.0	0.0	-0.9	-1.3	-0.3
Overall health rating	0.2	0.5	1.8	0.1	0.5	-0.3	1.3	-0.5	-0.5	-0.0	0.7	0.6	-1.0
Mood swings	0.2	0.4	2.2	0.3	-0.1	0.5	1.1	0.2	0.1	0.4	0.3	-1.5	-0.4
Commuting to job workplace: Public transport	0.2	0.2	0.5	0.7	0.4	0.6	0.0	0.2	-0.2	0.7	0.7	-0.2	0.5
Ever smoked	0.2	0.3	1.8	0.1	-0.5	-0.2	-0.4	0.1	0.2	-0.1	-0.3	1.4	0.6
Unable to work because of sickness or disability	0.2	0.3	1.5	-0.4	-0.1	0.1	-0.0	-0.6	0.4	-1.2	-0.0	0.4	-0.6
Neuroticism (2016)	0.1	0.2	0.7	-0.5	-0.2	0.4	-0.1	-0.3	0.7	-0.5	-0.0	-0.1	0.8
Respiratory disease	0.1	0.2	0.8	0.0	0.7	-0.0	0.9	0.1	-0.4	0.8	0.1	-0.4	0.1
Tinnitus: Yes, but not now, but have in the past	0.1	0.2	0.5	-0.7	-0.6	0.0	0.2	-0.5	0.2	-0.1	0.4	0.1	-0.3
Medication: Ibuprofen (e.g. Nurofen)	0.1	0.2	0.6	0.1	-0.0	-0.1	-0.1	-0.4	0.4	-0.3	-0.7	0.8	0.6
Mean time to correctly identify matches	0.1	0.2	0.6	0.2	0.5	0.0	-0.7	0.2	0.1	0.2	0.8	0.7	0.7

Hub : Genes

MAST4

Models

Trait associations