TWAS hub - MICU3

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Cells Transformed fibroblasts	0.1900	0.053	0.00064	0.051	NA	0.102	NA	0.086	9.7e-05	NA	4.7e-08	NA	5.7e-07
2	GTEx	Esophagus Gastroesophageal Junction	0.3410	0.102	0.00310	-0.003	NA	0.014	NA	0.036	4.1e-01	NA	9.7e-02	NA	1.8e-02
3	METSIM	Adipose	0.0586	0.023	0.00500	0.041	0.011	0.025	0.022	0.025	7.4e-07	0.0075	9.0e-05	0.00027	1.1e-04

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
Lung FEV1/FVC ratio	6.3	31.7	50.3	3.9	7.1	5.5
Frequency of tiredness / lethargy in last 2 weeks	5.6	9.1	12.6	-3.3	-3.5	-2.0
Osteoarthritis (self-reported)	3.3	4.3	12.2	-0.6	-0.5	-3.5
Waist circumference	3.1	11.4	22.4	-1.7	-3.0	-4.7
Diabetes (mother)	3.0	3.9	7.6	1.9	2.8	-0.6
Medication: Aspirin	3.0	3.9	10.4	-1.0	0.6	-3.2
Schizophrenia vs Biploar Disorder	2.8	3.7	4.6	2.1	1.7	-1.9
High blood pressure (mother)	2.8	3.9	7.2	-1.0	-1.8	-2.7
Exposure to tobacco smoke outside home	2.5	3.3	8.5	2.9	0.8	0.9
Medication: Levothyroxine sodium	2.4	4.1	5.2	-2.3	-1.7	-2.0
Emphysema/chronic bronchitis	2.4	2.8	4.9	-0.9	-1.6	-2.2
Mean time to correctly identify matches	2.4	4.5	7.6	0.8	2.8	2.3
Long-standing illness, disability or infirmity	2.4	3.7	5.7	-2.4	-2.0	-1.2
Neuroticism (2016)	2.3	3.3	6.2	-1.9	-2.5	0.6
Schizophrenia (2014)	2.3	5.0	10.9	-1.3	-1.5	-3.3
Medication: Aspirin	2.3	3.0	7.6	-0.9	0.7	-2.7
Worry (Nagel 2018)	2.1	4.4	10.0	-1.7	-3.2	0.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	2.1	4.5	7.6	1.3	2.1	2.8
Time employed in main current job	2.0	2.4	5.1	1.4	0.3	2.3
Chronic bronchitis/emphysema (mother)	2.0	2.3	6.1	0.9	-2.5	0.3
Medication: Gliclazide	2.0	2.3	4.8	-0.4	1.4	-2.2
Medication: Paracetamol	2.0	3.1	3.3	-1.8	-1.7	-1.8
Neuroticism (Nagel 2018)	1.9	4.4	9.2	-2.0	-3.0	-0.1
Waist Hip Ratio (WHR)	1.9	8.4	12.4	-0.6	-3.5	-3.5
Supplements: Zinc	1.9	2.0	3.9	-1.0	-1.1	-2.0
Taking other prescription medications	1.9	2.9	6.4	-2.5	-1.2	-0.9
Leg fat mass (left)	1.9	7.4	17.8	-1.3	-1.6	-4.2
Ovarian Cancer	1.8	2.4	3.7	-1.9	0.3	-1.9
Wheeze or whistling in the chest in last year	1.8	3.3	5.1	-0.9	-2.2	-2.0
Leg fat mass (right)	1.8	7.1	17.7	-1.2	-1.5	-4.2
Asthma (self-reported)	1.8	3.5	4.5	-2.0	-2.1	-1.4
Leg fat percentage (left)	1.8	6.6	16.6	-1.3	-1.2	-4.1
Primary Biliary Cirrhosis	1.7	2.4	2.9	-1.1	-1.7	-1.7
Current tobacco smoking	1.7	2.8	4.2	1.5	2.0	1.4
Serious illness, injury or assault to yourself	1.7	2.0	5.4	-2.3	-0.2	-0.8
Hip circumference	1.7	7.5	12.1	-2.0	-2.5	-3.5
Lung cancer (father)	1.7	2.0	3.0	-1.7	-1.7	-0.3
Length of working week for main job	1.7	1.9	4.6	-1.0	-2.2	-0.0
Tense / ‘highly strung’	1.7	2.9	6.4	-1.2	-2.5	0.8
Medication: Paracetamol	1.7	2.8	4.7	-1.6	-1.1	-2.2
Leg fat percentage (right)	1.7	6.2	16.3	-1.1	-1.1	-4.0
Whole body fat mass	1.7	7.0	14.4	-1.6	-2.0	-3.8
Commuting to job workplace: Cycle	1.7	2.0	5.7	0.6	-0.1	2.4
Alzheimer’s Disease (in mother)	1.6	1.9	5.7	-0.1	-0.3	2.4
Respiratory disease	1.6	3.5	4.4	-1.6	-1.8	-2.1
Trunk fat mass	1.6	7.1	12.5	-1.8	-2.3	-3.5
Weight	1.6	7.8	16.0	-1.5	-2.2	-4.0
Hypothyroidism/myxoedema (self-reported)	1.6	3.2	4.2	-2.1	-1.5	-1.8
Medication for pain relief, constipation, heartburn	1.6	2.8	4.6	2.1	0.2	1.9
Mouth/teeth dental problems: Mouth ulcers	1.6	2.5	5.9	-1.3	-2.4	-0.0
Osteoporosis (self-reported)	1.6	2.0	2.5	1.2	1.4	1.6
Arm fat mass (left)	1.6	6.6	15.8	-1.2	-1.7	-4.0
Unable to work because of sickness or disability	1.6	2.1	5.5	-2.3	-0.7	-0.7
Depressed Affect (Nagel 2018)	1.5	3.1	4.4	-2.1	-2.1	-0.9
Reaction Time	1.5	2.8	3.9	0.8	1.9	2.0
Prostate Cancer	1.5	2.1	3.8	-1.9	-1.5	-0.3
Body mass index (BMI)	1.5	6.4	15.6	-1.2	-1.4	-3.9
Illnesses of siblings	1.5	2.2	4.6	-1.3	-2.1	-0.6
Asthma	1.5	3.0	4.2	-1.7	-2.0	-1.4
Body fat percentage	1.5	5.8	11.4	-1.7	-1.8	-3.4
Shortness of breath walking on level ground	1.5	1.7	3.3	-1.3	-1.8	-0.3
Mouth/teeth dental problems: Loose teeth	1.5	1.8	4.1	1.0	-0.3	2.0
Friendships satisfaction	1.5	1.8	2.3	1.5	1.0	1.5
Bipolar Disorder (2018)	1.4	2.2	3.6	-1.7	-1.9	-0.0
Bipolar Disorder or Schizophrenia	1.4	3.4	4.4	-2.1	-1.8	-1.7
Depression (Nagel 2018)	1.4	2.0	5.0	-0.9	-2.2	-0.4
Alzheimer’s Disease (including proxy)	1.4	2.0	5.8	0.2	-0.2	2.4
Trunk fat percentage	1.4	5.6	8.2	-2.1	-2.1	-2.9
Had other major operations	1.4	1.7	2.6	1.6	0.2	1.6
Alcohol intake versus 10 years previously	1.4	2.1	3.2	1.7	1.8	-0.3
Depression (self-reported)	1.4	1.7	3.1	-1.0	-1.8	1.0
Arm fat mass (right)	1.4	5.8	14.0	-1.0	-1.6	-3.7
Medication: Seretide 50 evohaler	1.4	1.6	2.0	-1.4	-1.1	1.2
Suffer from ‘nerves’	1.4	2.1	4.5	-2.1	-1.3	0.4
Arm fat percentage (left)	1.4	5.5	13.2	-0.9	-1.6	-3.6
Smoking status: Current	1.4	2.3	3.9	1.3	2.0	1.1
Pain type(s) experienced in last month: Hip pain	1.4	1.8	3.0	-1.7	-1.4	-0.6
Medication: Omeprazole (e.g. Zanprol)	1.4	1.7	3.3	0.8	-1.8	1.1
Fasting Glucose	1.3	1.5	2.4	-1.2	-1.6	-0.8
Number of treatments/medications taken	1.3	2.3	4.3	-2.1	-0.8	-1.4
Angina	1.3	1.7	2.8	-1.4	-0.5	-1.7
Medication: Omeprazole	1.3	1.6	2.9	0.4	-1.7	1.3
Mood swings	1.3	2.4	4.4	-2.1	-1.5	-0.8
Illnesses of father: High blood pressure	1.3	1.6	2.5	1.6	1.0	-1.2
Schizophrenia (2018)	1.2	2.5	5.7	-1.2	-0.7	-2.4
Bipolar Disorder (2011)	1.2	1.2	1.9	-1.2	-1.4	-0.5
Other serious medical condition/disability diagnosed by doctor	1.2	1.6	3.9	-2.0	-0.9	-0.1
Townsend deprivation index at recruitment	1.2	1.6	3.3	1.8	-1.3	-0.1
Arm fat percentage (right)	1.2	4.5	10.8	-0.7	-1.5	-3.3
High blood pressure (siblings)	1.2	1.7	3.1	1.1	1.8	0.9
Illnesses of siblings: Diabetes	1.2	1.4	2.5	1.2	1.6	-0.7
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.2	1.5	2.3	-1.0	1.0	1.5
Ulcerative Colitis	1.1	1.6	2.5	-0.9	-1.6	1.2
Sensitivity / hurt feelings	1.1	2.0	5.8	-0.1	-2.4	0.4
Fed-up feelings	1.1	2.0	3.0	-1.7	-1.7	0.1
Serious illness, injury or assault of a close relative in last 2 years	1.1	1.3	2.3	-1.5	-1.1	-0.5
Breastfed as a baby	1.1	1.4	3.2	0.9	1.8	-0.3
Average weekly red wine intake	1.1	1.6	3.4	-1.1	-0.2	1.8
Number of self-reported non-cancer illnesses	1.1	1.9	2.8	-1.7	-1.7	-0.2
Medication: Bendroflumethiazide	1.1	1.7	2.2	1.2	1.5	-1.2
Ever smoked	1.1	2.0	3.2	1.8	1.5	0.6
Type 2 Diabetes (T2D) (2012)	1.0	1.2	1.8	-1.4	-0.9	-0.9
Hypothyroidism (self reported)	1.0	2.2	3.4	-1.8	-1.3	-1.2
Pack years adult smoking proportion	1.0	1.5	4.0	-0.5	-2.0	0.3
Leg fat-free mass (left)	1.0	5.1	10.2	-1.1	-2.0	-3.2
Leg predicted mass (left)	1.0	5.2	10.2	-1.2	-2.0	-3.2
Nervous feelings	1.0	1.9	2.2	-1.2	-1.5	1.4
Arm fat-free mass (right)	1.0	5.3	12.6	-1.1	-1.5	-3.5
Angina (self-reported)	1.0	1.3	2.1	-1.3	-0.5	-1.4
Migraine (self-reported)	1.0	1.2	3.4	0.1	-0.6	-1.8
Arm predicted mass (right)	1.0	5.1	12.0	-1.1	-1.5	-3.5
Illness, injury, bereavement, stress in last 2 years	1.0	1.2	2.6	1.6	0.8	0.6
Forced expiratory volume in 1-second (FEV1), predicted	1.0	2.1	3.0	-0.8	-1.7	-1.6
Breast cancer (self-reported)	1.0	1.2	3.0	0.6	1.7	-0.4
Medication: Blood pressure	1.0	1.9	3.2	1.1	1.1	-1.8
Average weekly beer plus cider intake	1.0	1.5	3.9	-0.7	0.4	-2.0
Cholesterol lowering medication	1.0	1.4	2.2	-0.2	-1.5	-1.4
Arm predicted mass (left)	1.0	5.2	11.6	-1.1	-1.7	-3.4
Age when periods started (menarche)	0.9	2.1	4.6	1.3	-0.4	2.1
Forced vital capacity (FVC)	0.9	3.6	7.6	-1.2	-2.8	-1.3
Heart attack	0.9	1.1	1.9	-1.4	-0.2	-1.2
Hayfever/allergic rhinitis (self-reported)	0.9	1.1	2.1	0.3	-1.1	1.5
Prospective memory result	0.9	1.1	1.6	-0.9	1.3	1.0
Exposure to tobacco smoke at home	0.9	1.0	2.8	0.3	-0.5	-1.7
Basal metabolic rate	0.9	5.2	11.0	-1.1	-1.8	-3.3
Arm fat-free mass (left)	0.9	4.7	11.2	-1.1	-1.3	-3.3
Body Mass Index (BMI) (2010)	0.8	1.0	2.5	-0.1	-1.6	-0.8
BMI	0.8	4.5	6.8	-0.9	-2.4	-2.6
Chronotype (morning person)	0.8	1.9	3.1	1.6	-0.1	1.8
Ever had hysterectomy (womb removed)	0.8	0.9	1.7	-0.4	-0.9	1.3
Eye problems/disorders: Diabetes related eye disease	0.8	0.9	1.1	0.8	-1.0	-1.0
Medication: Co-codamol	0.8	0.9	2.3	-0.4	-0.6	-1.5
Average weekly fortified wine intake	0.8	0.9	1.3	0.5	-1.2	-1.0
Diabetes (self-reported)	0.8	1.3	2.0	0.5	1.4	-1.3
Impedance of arm (right)	0.8	3.6	10.8	-0.0	0.0	3.3
Father’s age at death	0.8	1.1	2.0	-0.3	-1.0	-1.4
Headache pain in last month	0.8	1.5	3.3	-0.4	-1.8	-1.0
Medication: Amlodipine	0.8	1.1	2.6	0.0	1.6	0.8
Number of full sisters	0.8	0.9	2.1	-0.3	1.4	-0.8
Chest pain or discomfort	0.8	1.1	2.9	-0.5	-0.4	-1.7
Leg fat-free mass (right)	0.8	4.5	8.2	-1.2	-2.0	-2.9
Loneliness, isolation	0.8	1.1	3.1	-1.8	-0.3	-0.3
Ever had bowel cancer screening	0.8	0.9	1.9	-0.9	1.4	0.3
Ever had stillbirth, spontaneous miscarriage or termination	0.8	0.8	1.7	-0.9	-1.3	0.3
Back pain experienced in last month	0.8	1.1	2.6	-0.6	-0.6	-1.6
Leg predicted mass (right)	0.8	4.5	8.4	-1.3	-1.9	-2.9
Hearing aid user	0.8	0.9	1.6	-1.3	0.7	-0.8
Financial situation satisfaction	0.8	0.9	1.7	0.7	0.8	1.3
Tinnitus: Yes, now most or all of the time	0.8	0.9	2.6	-0.2	0.2	-1.6
Basal cell carcinoma (self-reported)	0.8	1.0	1.7	-1.1	-1.3	-0.3
HDL Cholesterol	0.7	1.1	2.4	0.2	1.5	-1.0
Smoking Status	0.7	1.6	2.5	1.5	1.6	-0.4
Type 2 Diabetes (T2D) (2018)	0.7	1.2	1.7	1.1	1.0	-1.3
Medication: Metformin	0.7	1.0	2.2	0.9	1.5	-0.4
Relative age voice broke	0.7	1.1	3.1	-0.4	-1.8	0.4
Qualifications: None of the above	0.7	1.5	4.0	0.1	0.7	-2.0
Allergy	0.7	1.5	4.0	0.8	2.0	-0.1
Neuroticism score	0.7	1.5	2.6	-1.3	-1.6	0.4
Qualifications: A levels/AS levels or equivalent	0.7	1.6	2.6	0.6	1.4	1.6
Mouth/teeth dental problems: Dentures	0.7	1.2	2.2	1.0	0.7	1.5
Pulse wave Arterial Stiffness index	0.7	0.8	2.4	-0.1	1.6	0.3
Loud music exposure frequency	0.7	0.8	1.1	-1.1	-0.4	-1.1
Worry too long after embarrassment	0.7	1.1	2.2	-1.5	-1.1	-0.3
Knee pain experienced in last month	0.7	1.0	2.8	1.7	-0.2	0.6
Diabetes diagnosed by doctor	0.7	1.2	2.0	0.7	1.4	-1.0
Ever had prostate specific antigen (PSA) test	0.7	0.9	2.4	0.2	0.3	1.6
Myopia	0.7	1.0	2.7	-1.6	-0.6	0.1
Heart attack/myocardial infarction (self-reported)	0.7	1.0	1.6	-1.2	-0.1	-1.1
Alcohol drinker status: Previous	0.7	0.8	1.4	0.9	0.6	1.2
Pack years of smoking	0.7	1.0	2.8	0.1	-1.7	0.5
Alzheimer’s Disease (in father)	0.6	0.7	1.0	1.0	-0.3	0.9
Crohns Disease (2017)	0.6	1.4	3.7	-0.7	-0.2	-1.9
Systolic Blood Pressure	0.6	3.0	8.1	0.4	2.8	-0.9
Neuroticism	0.6	1.5	4.3	-0.2	-2.1	-0.3
Hearing difficulty/problems: Yes	0.6	1.0	2.4	-0.1	1.6	0.7
Systolic blood pressure, automated reading	0.6	1.6	3.8	0.8	1.9	-0.8
Mouth/teeth dental problems	0.6	1.0	1.4	0.6	1.1	-1.2
Fluid intelligence score	0.6	1.2	2.8	0.4	-0.8	1.7
Impedance of arm (left)	0.6	2.6	7.8	-0.1	0.1	2.8
Birth weight of first child	0.6	1.1	1.3	-1.1	-1.0	-1.0
Pulse wave peak to peak time	0.6	0.7	1.9	0.3	-1.4	-0.2
Pulse rate, automated reading	0.6	1.9	2.6	-1.2	-1.6	-1.4
Whole body fat-free mass	0.6	3.5	7.6	-0.9	-1.5	-2.8
Qualifications: nursing, teaching	0.6	0.9	2.0	-1.4	-0.8	-0.2
Eye problems/disorders: Cataract	0.6	0.7	2.0	0.4	0.3	-1.4
Mineral and other dietary supplements	0.6	0.8	1.9	1.4	0.6	-0.1
Whole body water mass	0.6	3.5	7.7	-0.9	-1.4	-2.8
Alcohol drinker status: Never	0.6	0.7	1.5	-1.2	0.5	-0.6
Irritability	0.6	1.0	2.8	-0.3	-0.3	1.7
Verbal and Numeric Reasoning (VNR)	0.5	1.2	3.1	-0.2	-0.7	1.8
Breast Cancer	0.5	1.1	2.7	0.7	-0.5	1.6
Age at First Birth	0.5	0.8	2.3	0.0	0.3	1.5
Ever used hormone-replacement therapy (HRT)	0.5	0.6	1.2	-0.8	-1.1	-0.2
Vitamin and mineral supplements	0.5	0.7	1.1	-0.0	1.0	-1.0
High blood pressure	0.5	1.3	2.7	0.9	1.6	0.6
Worrier / anxious feelings	0.5	1.0	1.7	-1.3	-1.0	0.7
Seen doctor (GP) for nerves, anxiety, tension or depression	0.5	0.7	1.5	-1.2	-0.8	-0.1
Hair/balding pattern: Pattern 4	0.5	1.2	2.8	-0.5	1.7	-0.7
Birth weight	0.5	1.1	3.0	-0.2	-1.7	-0.4
Seen a psychiatrist for nerves, anxiety, tension or depression	0.5	0.7	0.9	-0.9	-0.6	-0.9
Age at first live birth	0.5	0.9	1.6	0.3	1.2	-1.0
Heart disease (mother)	0.5	0.6	1.5	-0.4	-1.2	0.4
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.5	0.6	0.7	0.7	0.9	0.8
Had major operations	0.5	0.6	1.5	-1.2	0.4	-0.3
Qualifications: NVQ or HND or HNC or equivalent	0.5	0.6	0.9	0.2	0.9	1.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.5	0.5	1.2	-0.3	-0.5	1.1
Guilty feelings	0.5	0.8	2.1	-1.5	-0.5	-0.2
Risk taking	0.5	0.8	2.2	0.3	-1.5	-0.2
Impedance of whole body	0.5	2.6	7.7	-0.3	0.2	2.8
Irritable Bowel Disease (IBD)	0.4	0.8	1.1	-1.1	-1.0	-0.6
Ulcerative Colitis (UC)	0.4	0.8	1.4	-0.7	-1.2	0.6
Major Depression (MDD)	0.4	0.4	1.1	-1.0	-0.3	0.4
Coronary Artery Disease (CAD)	0.4	0.4	1.3	0.1	1.1	-0.2
Crohns Disease (2012)	0.4	0.6	0.8	0.5	-0.9	-0.9
Mean Putamen Volume	0.4	0.5	1.2	-0.4	-0.3	-1.1
Triglycerides	0.4	0.7	1.7	0.0	0.6	1.3
Blood Eosinophil Count	0.4	3.0	5.3	2.3	0.7	1.8
Cardiovascular Disease	0.4	1.2	2.2	1.1	0.0	1.5
Frequency of depressed mood in last 2 weeks	0.4	0.5	0.9	-0.9	-0.9	0.1
Diabetes (father)	0.4	0.5	1.1	-0.1	-0.5	-1.1
Tinnitus: Yes, but not now, but have in the past	0.4	0.4	1.1	-0.1	1.0	0.3
Medication: Atenolol	0.4	0.5	0.5	-0.7	-0.7	-0.7
Past tobacco smoking	0.4	0.7	1.1	-1.0	-1.1	0.4
Frequency of tenseness / restlessness in last 2 weeks	0.4	0.7	1.5	-1.2	-0.6	-0.5
Hearing difficulty/problems with background noise	0.4	0.7	2.0	0.2	1.4	0.0
Ever unenthusiastic/disinterested for a whole week	0.4	0.5	1.3	-0.4	1.1	-0.2
Pain all over the body in last month	0.4	0.4	0.8	0.3	0.6	-0.9
Trunk fat-free mass	0.4	2.5	6.4	-0.5	-0.9	-2.5
Falls in the last year	0.4	0.5	1.2	-0.3	1.1	0.4
Medication: Ibuprofen (e.g. Nurofen)	0.4	0.5	1.0	-1.0	0.3	-0.7
Medication: Lansoprazole	0.4	0.4	0.7	-0.7	-0.3	-0.8
Trunk predicted mass	0.4	2.5	6.4	-0.4	-0.9	-2.5
Forced vital capacity (FVC), Best measure	0.4	1.4	2.9	-0.7	-1.7	-0.8
Number of children fathered	0.4	0.4	0.9	0.3	-1.0	-0.5
Eye problems/disorders: None of the above	0.4	0.5	1.1	-0.6	-0.2	1.1
Overall health rating	0.4	0.8	1.6	-0.5	-1.3	-0.6
Smoking status: Previous	0.4	0.7	1.7	0.5	-0.1	-1.3
Illnesses of father: None of the above (group 1)	0.4	0.5	1.2	-1.1	-0.6	0.1
Miserableness	0.4	0.7	1.1	-1.1	-1.1	0.1
Wears glasses or contact lenses	0.4	0.5	0.9	-0.6	0.3	0.9
Mother’s age at death	0.4	0.5	1.2	0.2	0.5	1.1
Commuting to job workplace: Public transport	0.4	0.5	1.1	-1.0	-0.3	0.5
Supplements: Fish oil (including cod liver oil)	0.4	0.5	1.1	-1.0	-0.4	0.4
Age started oral contraceptive pill	0.4	0.5	1.0	0.6	0.5	-1.0
Supplements: Calcium	0.4	0.4	0.7	0.8	0.8	-0.2
HbA1C	0.3	0.4	0.6	-0.7	-0.8	0.3
LDL Cholesterol	0.3	0.4	1.1	0.1	0.4	1.1
Lupus	0.3	0.4	1.2	0.2	-1.1	0.2
Rheumatoid Arthritis	0.3	0.4	1.3	-0.2	1.1	-0.0
Lung FVC	0.3	1.6	2.4	-1.5	-1.6	-0.3
Severe depression (siblings)	0.3	0.3	0.9	0.3	0.9	0.2
Hand grip strength (right)	0.3	0.7	1.5	-0.5	-1.2	-0.7
Frequency of unenthusiasm / disinterest in last 2 weeks	0.3	0.4	0.9	-0.9	-0.7	0.1
Hayfever, allergic rhinitis or eczema	0.3	0.6	1.6	0.5	0.0	1.2
Multivitamins +/- minerals	0.3	0.4	0.8	0.6	-0.9	-0.2
Stomach or abdominal pain in last month	0.3	0.3	0.8	0.3	-0.2	-0.9
Diverticular disease/diverticulitis (self-reported)	0.3	0.3	0.5	-0.4	0.6	0.7
Chronic bronchitis/emphysema (father)	0.3	0.3	1.0	-1.0	0.1	0.1
Impedance of leg (left)	0.3	1.4	3.9	-0.5	0.4	2.0
Alcohol usually taken with meals	0.3	0.5	0.8	-0.9	-0.0	0.8
Had menopause	0.3	0.3	0.5	-0.7	0.0	0.7
Heel bone mineral density (BMD) T-score, automated (right)	0.3	0.7	1.9	1.4	0.4	-0.2
Financial difficulties in last 2 years	0.3	0.5	0.7	0.4	0.7	0.8
Hair/balding pattern: Pattern 3	0.3	0.5	0.7	0.8	-0.8	-0.1
Noisy workplace	0.3	0.3	0.6	0.5	-0.8	0.3
Qualifications: O levels/GCSEs or equivalent	0.3	0.4	1.1	-0.1	0.3	-1.1
Mouth/teeth dental problems: Bleeding gums	0.3	0.4	0.6	-0.4	0.7	0.8
Blood clot in the leg (DVT)	0.3	0.4	0.5	-0.5	-0.7	0.6
Medication for cholesterol, blood pressure or diabetes	0.3	0.5	1.0	1.0	0.3	-0.7
Glaucoma (self-reported)	0.3	0.4	1.1	0.3	1.1	0.1
Gout (self-reported)	0.3	0.5	1.3	0.4	-0.1	1.1
Medication: Ibuprofen	0.3	0.4	0.7	-0.8	-0.4	-0.6
Age at last live birth	0.3	0.5	1.2	0.2	0.4	-1.1
Hypertension (Self-reported)	0.3	0.9	2.3	0.7	1.5	0.2
Handedness (chirality/laterality): Left-handed	0.3	0.4	1.1	1.0	0.0	-0.0
Eye problems/disorders: Glaucoma	0.3	0.3	0.7	-0.3	-0.5	-0.9
Medication: Atorvastatin	0.3	0.3	0.8	-0.9	0.1	-0.5
Fractured/broken bones in last 5 years	0.3	0.4	0.6	-0.8	0.1	-0.7
Ever depressed for a whole week	0.3	0.4	0.8	-0.5	0.9	-0.2
Pain experienced in last month	0.3	0.5	0.8	0.0	0.8	0.9
Heart disease (siblings)	0.3	0.3	0.9	0.2	-0.9	0.2
Intelligence (Savage-Jansen 2018)	0.2	0.6	1.2	-0.0	-1.1	0.8
Allergy or Eczema	0.2	0.5	0.8	0.9	0.1	0.9
Hand grip strength (left)	0.2	0.5	1.4	-0.3	-1.2	-0.3
Average weekly spirits intake	0.2	0.3	0.4	0.6	0.6	0.0
Relative age of first facial hair	0.2	0.4	1.0	0.1	-1.0	-0.4
Medication for hormone replacement therapy	0.2	0.2	0.3	-0.1	-0.6	0.5
Impedance of leg (right)	0.2	1.1	3.1	-0.2	0.5	1.8
Maternal smoking around birth	0.2	0.2	0.3	-0.6	0.3	0.5
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.6	1.2	1.1	-0.5	-0.5
Supplements: Glucosamine	0.2	0.2	0.6	0.2	-0.2	0.7
Sitting height	0.2	1.1	2.9	-0.4	-1.7	-0.5
Number of incorrect matches in round	0.2	0.4	0.7	-0.4	0.4	-0.8
Hair/balding pattern: Pattern 2	0.2	0.3	0.5	0.3	0.7	0.5
Illnesses of mother	0.2	0.3	0.5	-0.7	0.4	-0.5
Standing height	0.2	1.5	3.3	-1.1	-1.8	-0.3
Medication: Ventolin 100micrograms inhaler	0.2	0.3	0.8	0.2	-0.9	0.1
Comparative body size at age 10	0.2	0.7	1.1	-0.1	-0.9	-1.1
Number of full brothers	0.2	0.2	0.4	0.6	-0.1	0.5
Health satisfaction	0.2	0.3	0.5	-0.5	-0.7	-0.3
Qualifications: College or University degree	0.2	0.7	1.1	-0.9	-1.0	0.3
Neck or shoulder pain in last month	0.2	0.2	0.5	-0.3	0.2	-0.7
Medication: Blood pressure	0.2	0.3	0.7	-0.5	-0.2	0.8
Medication: Allopurinol	0.2	0.3	0.8	0.3	0.2	0.9
Family relationship satisfaction	0.2	0.3	0.5	0.7	-0.5	-0.4
Leg pain on walking	0.2	0.3	0.7	0.9	-0.2	-0.2
Illnesses of father: Heart disease	0.2	0.3	0.7	-0.3	0.2	-0.8
Medication for cholesterol	0.2	0.3	0.6	-0.3	0.7	0.6
Average weekly champagne plus white wine intake	0.2	0.3	0.6	-0.8	-0.6	0.1
Ever taken oral contraceptive pill	0.2	0.2	0.3	0.6	0.6	-0.2
High cholesterol (Self-reported)	0.2	0.3	0.9	0.9	-0.3	0.1
Medication: Lisinopril	0.2	0.2	0.4	-0.1	0.7	-0.4
Number of operations (self-reported)	0.2	0.2	0.4	-0.4	-0.6	-0.5
Diastolic blood pressure, automated reading	0.2	0.5	0.9	-1.0	-0.0	-0.7
Vascular/heart problems diagnosed by doctor	0.2	0.6	1.7	-0.2	-1.3	-0.2
Deep venous thrombosis (DVT) (self-reported)	0.2	0.2	0.5	-0.3	-0.7	0.4
Blood Red Count	0.1	0.9	1.5	-0.4	-1.2	-1.0
Blood White Count	0.1	0.6	1.6	0.2	-1.3	-0.3
Heel T-Score	0.1	0.7	1.8	-0.3	-0.3	-1.4
Tanning	0.1	1.5	2.2	1.0	1.1	-1.5
Bilateral oophorectomy (both ovaries removed)	0.1	0.1	0.2	0.5	0.1	0.3
Qualifications: CSEs or equivalent	0.1	0.2	0.3	0.4	-0.2	-0.5
Number of live births	0.1	0.1	0.3	-0.1	0.6	0.1
Forced expiratory volume in 1-second (FEV1)	0.1	0.3	0.7	0.1	-0.8	0.4
Happiness	0.1	0.1	0.3	0.5	0.2	0.2
Medication: Cholesterol lowering	0.1	0.1	0.1	-0.3	-0.2	0.4
Pulse wave reflection index	0.1	0.1	0.3	0.6	-0.3	-0.0
Ever highly irritable/argumentative for 2 days	0.1	0.1	0.2	-0.2	0.5	-0.3
Reason for reducing amount of alcohol drunk: Health precaution	0.1	0.1	0.1	-0.3	0.1	0.3
Alcohol intake frequency.	0.1	0.3	0.7	-0.0	0.9	0.5
Comparative height size at age 10	0.1	0.7	1.9	-0.3	0.1	-1.4
Commuting to job workplace: Car/motor vehicle	0.1	0.1	0.2	-0.2	0.4	-0.1
Blood Platelet Count	0.0	0.3	0.8	-0.0	-0.9	0.2
Height	0.0	0.5	0.8	-0.9	-0.8	0.4
Hair Pigment	0.0	0.2	0.4	0.6	-0.6	0.2
Medication: Ramipril	0.0	0.1	0.1	-0.4	-0.2	-0.1
Medication: Simvastatin	0.0	0.0	0.1	0.3	0.0	0.2
Pulse rate	0.0	0.1	0.1	-0.3	-0.3	-0.0
Forced expiratory volume in 1-second (FEV1), Best measure	0.0	0.2	0.3	0.4	0.1	0.5
Peak expiratory flow (PEF)	0.0	0.1	0.1	-0.2	0.4	0.1
Supplements: Vitamin C	0.0	0.0	0.1	0.2	0.2	0.0
Commuting to job workplace: Walk	0.0	0.0	0.1	0.2	-0.1	-0.2

Hub : Genes

MICU3

Models

Trait associations