TWAS hub - MIS12

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1450	0.0350	1.3e-07	0.076	0.057	0.074	0.087	0.102	1.7e-09	1.9e-07	2.8e-09	8.8e-11	2.1e-12
2	GTEx	Brain Hippocampus	0.3552	0.1220	7.9e-03	-0.011	NA	0.034	NA	-0.011	7.2e-01	NA	5.5e-02	NA	7.4e-01
3	GTEx	Esophagus Muscularis	0.1930	0.0650	8.2e-04	0.006	NA	0.012	NA	0.023	1.3e-01	NA	6.1e-02	NA	1.4e-02
4	GTEx	Lung	0.0831	0.0369	6.1e-03	0.019	NA	0.019	NA	0.022	1.2e-02	NA	1.3e-02	NA	8.1e-03
5	GTEx	Nerve Tibial	0.0956	0.0393	4.8e-03	0.022	NA	0.042	NA	0.033	9.7e-03	NA	5.5e-04	NA	2.2e-03
6	GTEx	Pancreas	0.1750	0.0660	1.6e-03	0.119	NA	0.026	NA	0.095	1.0e-05	NA	2.8e-02	NA	8.5e-05
7	GTEx	Skin Sun Exposed Lower leg	0.2280	0.0640	2.1e-04	0.034	NA	0.030	NA	0.039	7.3e-04	NA	1.5e-03	NA	3.4e-04
8	GTEx	Thyroid	0.0590	0.0250	4.0e-03	0.010	NA	0.024	NA	0.027	5.4e-02	NA	5.4e-03	NA	3.5e-03
9	METSIM	Adipose	0.1363	0.0273	1.7e-15	0.120	0.125	0.142	0.132	0.138	1.9e-17	3.2e-18	1.2e-20	3.4e-19	5.0e-20
10	ROSMAP	Brain Pre-frontal Cortex	0.1537	0.0404	2.0e-06	0.019	0.055	0.079	0.088	0.075	1.4e-03	1.1e-07	2.1e-10	2.0e-11	6.1e-10
11	YFS	Blood	0.1813	0.0297	0.0e+00	0.099	0.133	0.164	0.163	0.158	9.5e-31	2.2e-41	3.8e-51	8.1e-51	2.1e-49
12	TCGA	Colon Adenocarcinoma	0.0780	0.0410	8.8e-03	0.006	0.041	0.031	NA	0.015	1.4e-01	2.1e-03	6.3e-03	NA	4.2e-02
13	TCGA	Kidney Renal Clear Cell Carcinoma	0.0498	0.0258	7.2e-03	0.014	0.012	0.020	NA	0.015	1.0e-02	1.3e-02	2.1e-03	NA	6.7e-03
14	TCGA	Kidney Renal Papillary Cell Carcinoma	0.1380	0.0680	7.1e-03	0.010	0.052	0.037	NA	0.013	8.2e-02	6.0e-04	3.2e-03	NA	5.4e-02
15	TCGA	Thyroid Carcinoma	0.0630	0.0310	7.5e-03	0.013	0.001	0.000	NA	0.021	1.6e-02	2.2e-01	2.9e-01	NA	3.6e-03

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	3	4	5	6	7	8	9	10	11	12	13	14	15
Had menopause	3.6	4.5	16.6	-1.2	1.3	3.9	2.6	4.1	1.7	3.1	1.1	0.3	1.4	2.1	-0.0	-0.8	2.4
Reproduciblity of spirometry measurement using ERS/ATS criteria	3.3	4.0	9.3	-1.0	-2.5	-3.0	-2.5	-1.7	-2.2	-1.5	-2.7	-2.0	-1.9	-1.7	-1.9	-0.3	-2.3
Nervous feelings	3.2	5.9	17.3	0.7	2.9	3.7	3.5	3.4	1.4	4.2	1.9	-0.3	2.0	1.7	-0.3	1.2	3.3
Ever taken oral contraceptive pill	3.1	3.4	11.9	0.6	-1.8	-3.4	-2.4	-2.6	-1.6	-3.0	-1.4	-0.1	0.0	-0.3	-0.4	0.1	-3.1
Reaction Time	2.8	5.3	18.7	4.3	2.1	-0.4	0.1	-3.3	1.2	-1.7	2.7	2.0	3.2	0.8	2.2	3.6	1.1
Body Mass Index (BMI) (2010)	2.8	3.9	16.6	2.9	0.3	-1.1	-1.5	-4.1	-0.4	-2.9	1.2	1.8	0.9	0.5	3.4	1.8	0.1
Ever used hormone-replacement therapy (HRT)	2.8	3.5	15.6	0.4	2.0	2.8	1.2	2.4	0.1	4.0	1.6	0.8	2.1	2.2	0.5	0.7	2.3
Bipolar Disorder (2011)	2.5	2.5	8.2	-2.9	-1.4	-0.0	-1.5	2.8	-0.4	1.5	-2.2	-1.6	-0.7	0.0	-1.8	-1.3	-1.2
Mouth/teeth dental problems: Dentures	2.5	4.2	9.4	0.7	2.8	2.9	0.8	2.0	1.8	3.0	2.0	1.2	2.0	2.7	1.5	1.2	3.1
Osteoporosis (self-reported)	2.4	2.9	9.3	-0.2	1.8	1.7	1.3	2.5	1.8	3.0	1.6	1.2	1.3	1.9	1.4	1.0	2.3
Emphysema/chronic bronchitis	2.3	2.6	8.9	2.1	2.0	1.0	1.3	-0.6	1.8	-0.2	2.4	1.6	1.2	0.5	3.0	1.5	2.0
Hearing difficulty/problems with background noise	2.2	3.6	9.0	2.3	2.4	1.9	1.0	0.3	2.2	0.6	2.2	1.1	3.0	1.2	1.8	2.6	2.6
Ever smoked	2.2	3.9	9.1	-1.9	-3.0	-3.0	-2.2	-1.0	-1.0	-1.4	-2.3	-0.8	-2.2	-1.9	-1.1	-1.8	-2.8
Mouth/teeth dental problems	2.1	3.3	9.5	0.0	-2.5	-3.1	-2.0	-2.4	-1.1	-2.3	-1.8	-0.3	-1.3	-2.0	-0.9	-0.6	-2.7
Prospective memory result	2.1	2.5	11.9	-1.6	0.2	1.5	2.2	3.4	0.5	3.1	0.1	0.4	1.2	1.5	-1.1	-0.9	0.2
Qualifications: O levels/GCSEs or equivalent	2.0	3.2	9.4	0.1	-2.2	-2.6	-1.5	-2.7	-2.0	-3.1	-1.5	-0.7	-1.1	-1.6	-0.8	-0.2	-2.4
Tense / ‘highly strung’	1.9	3.2	16.3	-1.2	0.3	1.4	1.8	3.3	1.9	4.0	-0.3	-1.1	-0.1	-0.9	-2.4	-1.3	0.1
Medication: Seretide 50 evohaler	1.9	2.2	6.4	1.5	1.8	1.8	1.0	0.1	0.4	0.0	1.9	0.7	1.3	2.4	2.1	0.8	2.5
Commuting to job workplace: Walk	1.9	2.0	10.8	-1.2	0.9	1.6	0.8	2.4	2.2	3.3	0.1	-0.4	-0.8	-1.3	-0.7	-0.5	1.1
Irritability	1.9	3.2	9.5	-1.8	-1.9	-2.1	-1.3	0.5	-1.1	-0.4	-2.5	-2.5	-1.2	-1.7	-3.1	-0.7	-2.4
Age started oral contraceptive pill	1.9	2.4	14.3	-0.7	1.0	1.9	1.8	2.8	0.9	3.8	0.3	-0.0	1.4	0.4	-1.2	0.1	1.0
Basal cell carcinoma (self-reported)	1.9	2.2	4.8	-1.1	-1.7	-1.5	-1.6	-0.3	-1.5	-1.4	-1.6	-1.1	-1.9	-1.9	-1.3	-2.2	-1.9
Ulcerative Colitis (UC)	1.8	3.5	8.4	0.6	2.1	2.8	2.9	2.2	-0.1	1.8	1.5	0.9	2.6	1.6	0.3	2.3	2.2
Blood White Count	1.8	13.6	74.0	3.7	-0.3	-4.7	-4.0	-7.7	-2.8	-8.6	-0.3	-0.4	-0.0	-0.1	2.1	2.2	-1.9
Illnesses of father: High blood pressure	1.8	2.2	6.8	0.9	2.2	1.7	1.3	1.0	2.1	2.6	1.5	0.7	1.2	0.3	-0.4	1.6	2.0
Rheumatoid Arthritis	1.7	2.3	8.1	-1.2	-2.8	-1.8	-0.5	-0.9	-1.6	-2.4	-1.6	0.5	-1.7	-0.7	-0.1	-1.6	-2.1
Frequency of tenseness / restlessness in last 2 weeks	1.7	2.6	9.6	-0.2	2.3	2.3	2.1	2.3	1.4	3.1	1.1	-0.4	0.5	1.4	-0.2	0.1	2.0
Pulse wave reflection index	1.7	2.1	5.5	-1.5	-2.3	-1.7	-1.5	-0.8	-0.6	-0.9	-2.3	-1.4	-1.9	-0.2	-1.4	-0.7	-1.9
Mean time to correctly identify matches	1.7	3.3	9.9	3.1	1.9	0.2	0.1	-1.9	1.5	-0.3	2.2	1.8	2.9	0.8	1.6	2.9	1.2
Hearing aid user	1.7	1.9	6.0	-0.1	-1.6	-2.5	-1.7	-1.8	-1.3	-0.7	-0.7	1.1	-0.7	-1.6	0.1	-1.0	-2.4
Illness, injury, bereavement, stress in last 2 years	1.6	1.9	10.4	-1.4	0.3	2.0	1.7	3.2	1.2	2.4	-0.3	0.5	0.6	0.6	-0.9	-0.0	0.7
Illnesses of father: Heart disease	1.6	2.2	7.0	-0.1	1.5	2.0	1.0	1.5	0.6	1.6	1.6	0.8	1.7	2.6	1.0	0.1	2.5
Medication: Lisinopril	1.6	2.1	9.5	-2.3	-0.2	0.8	-0.8	3.1	-0.5	2.3	-1.1	-1.4	-0.8	-0.5	-2.0	-1.3	-0.0
Hearing difficulty/problems: Yes	1.5	2.3	5.8	1.6	2.0	1.7	-0.0	0.2	1.1	0.8	1.9	1.2	1.9	1.3	2.0	1.7	2.4
Number of live births	1.5	2.1	5.3	2.3	1.8	1.0	0.7	-1.0	0.3	0.4	1.8	0.7	1.0	1.3	2.1	2.3	2.1
Age at first live birth	1.5	2.7	6.9	-2.1	-2.5	-1.8	-1.5	0.3	-0.6	-1.5	-2.1	-0.9	-0.9	-0.8	-1.9	-2.2	-2.6
Migraine (self-reported)	1.5	1.9	5.2	-0.2	-1.7	-2.1	-0.4	-1.4	-0.2	-2.3	-1.1	0.8	-1.3	-1.9	-0.7	-1.0	-2.1
Medication: Atorvastatin	1.5	1.8	5.6	0.7	1.4	1.6	1.4	1.5	0.5	2.4	1.3	1.2	1.9	1.2	0.0	1.6	1.4
Ever had prostate specific antigen (PSA) test	1.5	1.8	7.1	1.7	1.0	1.0	0.1	-1.0	-0.8	-0.4	1.8	2.7	1.9	0.5	2.1	1.1	0.8
Depression (Nagel 2018)	1.4	2.1	6.2	-0.6	1.8	1.9	1.0	2.5	1.5	1.3	1.6	1.5	1.3	1.0	1.7	0.9	1.6
Schizophrenia (2014)	1.4	3.0	17.1	-1.5	1.2	2.9	0.4	4.1	0.6	3.0	0.1	-0.6	1.0	1.1	-0.4	-0.1	2.0
Chronotype (morning person)	1.4	3.3	10.2	-0.7	1.8	2.5	1.9	3.2	-0.8	3.1	1.8	1.8	1.2	1.3	0.6	1.0	2.2
Qualifications: None of the above	1.4	3.0	6.7	2.0	2.4	2.4	1.5	0.8	0.4	1.3	2.2	1.3	2.2	1.3	1.5	1.8	2.6
Medication: Amlodipine	1.4	2.0	7.5	-1.8	0.1	1.3	1.2	2.7	0.0	2.2	-0.7	-1.5	-0.3	0.5	-1.9	-2.1	0.1
Number of children fathered	1.4	1.6	8.9	-0.4	-0.6	-0.6	-1.8	-1.2	-3.0	-2.1	-0.8	-1.7	-1.0	0.2	-0.3	-0.2	-0.4
Leg fat mass (right)	1.4	5.3	25.9	1.9	-1.1	-2.9	-3.3	-5.1	-1.4	-4.3	0.1	1.0	-0.2	1.2	2.0	-0.4	-1.5
Commuting to job workplace: Car/motor vehicle	1.4	1.6	7.0	0.1	-1.6	-2.0	-0.9	-1.3	-2.2	-2.6	-0.7	0.1	-0.0	-0.6	-0.2	-0.1	-1.5
Alzheimer’s Disease (including proxy)	1.3	1.8	9.3	1.2	0.3	-1.7	-1.6	-2.6	0.1	-3.1	0.2	-0.4	0.4	1.3	0.9	1.0	-0.8
Verbal and Numeric Reasoning (VNR)	1.3	3.0	10.0	-2.8	-1.8	-0.7	-1.7	0.4	-0.4	-0.7	-2.6	-2.1	-3.2	-0.5	-1.2	-2.2	-1.5
Tinnitus: Yes, but not now, but have in the past	1.3	1.4	4.8	2.2	1.1	0.2	-0.2	-1.9	-0.3	-0.8	1.2	1.3	1.3	0.6	1.5	1.7	0.5
Happiness	1.3	1.6	7.3	-0.6	0.8	1.7	1.0	2.2	2.0	2.7	0.4	-0.4	0.8	0.3	-0.3	0.0	0.9
Leg fat mass (left)	1.3	5.1	24.6	2.0	-0.9	-2.8	-3.2	-5.0	-1.4	-4.2	0.3	1.0	0.2	1.3	2.0	-0.2	-1.3
Bipolar Disorder (2018)	1.2	2.0	7.7	-2.5	-0.9	-0.2	-0.6	2.8	-1.4	1.6	-1.9	-1.4	-0.7	0.6	-1.6	-1.0	-0.6
Blood Platelet Count	1.2	14.5	51.0	5.4	3.6	-0.0	-1.1	-4.7	2.2	-3.1	4.8	4.8	2.9	1.9	7.1	4.2	3.1
Lung cancer (father)	1.2	1.5	3.5	-1.0	-1.5	-1.2	-1.0	-0.3	-0.1	-1.9	-1.6	-1.7	-1.1	-1.1	-1.5	-0.6	-1.4
Illnesses of siblings: Diabetes	1.2	1.5	4.4	-2.1	-1.2	-0.2	0.7	2.0	-0.2	1.4	-1.5	-0.7	-1.0	-0.3	-1.6	-1.5	-1.0
Worry (Nagel 2018)	1.1	2.4	11.4	-0.8	1.0	2.0	2.3	3.4	1.5	2.8	-0.0	-1.1	0.4	-0.2	-1.3	-0.0	1.0
Irritable Bowel Disease (IBD)	1.1	2.7	6.8	1.1	1.9	2.2	2.1	0.9	-0.0	0.6	1.4	0.5	2.5	2.3	0.5	2.6	2.0
Crohns Disease (2012)	1.1	1.7	5.0	1.2	1.4	1.8	1.5	0.2	2.2	0.3	1.4	0.1	1.9	1.6	0.4	1.2	1.5
Average weekly spirits intake	1.1	1.4	4.8	2.0	0.5	-0.2	-1.8	-2.2	-0.3	-0.6	1.3	1.0	0.7	0.8	2.0	0.3	0.7
Sensitivity / hurt feelings	1.1	1.9	4.7	-2.2	-1.7	-1.1	-1.2	1.0	0.1	0.6	-1.8	-1.0	-1.8	-1.0	-1.4	-2.0	-1.6
Stomach or abdominal pain in last month	1.1	1.4	3.3	-1.8	-0.1	0.0	-1.0	1.6	0.1	1.1	-1.1	-1.8	-1.7	-1.0	-1.5	-1.6	-0.2
Past tobacco smoking	1.1	2.0	5.9	1.0	2.3	2.4	1.3	1.1	1.0	1.3	1.5	0.5	1.1	1.7	0.6	1.2	1.9
Noisy workplace	1.1	1.3	4.7	2.2	1.1	-0.3	0.0	-1.5	-1.3	-0.3	1.4	1.2	1.6	0.3	1.4	1.3	0.7
Serious illness, injury or assault of a close relative in last 2 years	1.1	1.3	3.8	0.6	-0.4	-1.2	-1.5	-2.0	-1.6	-1.8	-0.8	-1.3	0.1	1.0	-0.8	-0.7	-0.9
Pulse wave Arterial Stiffness index	1.1	1.2	5.2	-0.8	-1.2	-1.7	0.1	-0.5	2.3	-0.0	-1.4	-1.3	-1.0	0.3	-1.1	-0.4	-1.4
Leg fat percentage (right)	1.1	3.9	17.0	1.9	-0.5	-1.8	-2.5	-4.1	-1.4	-3.6	0.5	1.5	0.5	2.2	2.2	-0.0	-0.8
Ever had bowel cancer screening	1.1	1.2	7.0	-0.1	0.5	1.3	0.4	1.5	-0.1	2.6	0.9	1.6	1.2	0.7	1.0	-0.1	1.1
Back pain experienced in last month	1.1	1.6	4.6	0.1	-0.5	-1.9	-1.7	-1.6	-1.7	-0.3	-1.4	-2.1	-1.8	-1.2	-0.7	0.5	-0.5
Pain type(s) experienced in last month: Hip pain	1.1	1.3	4.9	1.6	1.2	-0.0	-1.1	-1.4	-0.9	0.2	1.7	1.7	0.5	0.1	2.2	0.6	1.0
High cholesterol (Self-reported)	1.1	2.0	6.0	-0.2	1.2	2.5	0.7	2.0	0.1	1.8	1.5	1.2	1.5	2.1	0.9	-0.2	1.9
Leg fat percentage (left)	1.1	3.9	16.5	2.1	-0.4	-1.8	-2.3	-4.1	-1.6	-3.7	0.7	1.5	0.9	2.2	2.0	0.1	-0.7
Average weekly beer plus cider intake	1.1	1.6	5.6	-1.1	-1.4	-1.5	-0.4	-0.5	-0.8	-1.3	-1.3	-0.5	-1.6	-2.4	-0.7	-1.2	-1.7
Lupus	1.0	1.4	7.1	-1.5	-1.6	-0.3	-0.1	0.6	2.7	-0.9	-1.8	-0.8	-0.9	-0.3	-1.6	-0.5	-0.9
BMI	1.0	5.7	27.5	2.7	-0.1	-2.8	-3.3	-5.2	-0.4	-4.2	1.2	1.4	0.3	1.2	3.1	0.4	-0.6
Eye problems/disorders: Diabetes related eye disease	1.0	1.1	3.3	-1.8	-0.2	0.0	-1.1	1.8	-0.2	0.4	-1.3	-1.8	-1.2	-0.7	-1.4	-0.2	-0.5
Diabetes (mother)	1.0	1.2	4.5	0.1	0.2	-1.1	-1.7	-1.5	-1.6	0.1	-1.1	-2.1	-1.9	-0.2	-0.3	-0.1	-0.2
Frequency of unenthusiasm / disinterest in last 2 weeks	1.0	1.3	3.7	0.0	1.7	1.9	1.2	1.8	0.0	1.4	1.1	-0.1	0.8	1.2	0.6	0.7	1.6
Serious illness, injury or assault to yourself	1.0	1.3	4.7	2.2	1.0	-0.1	0.0	-1.4	-1.4	-0.7	1.1	-0.1	1.2	-0.3	0.9	2.1	1.1
Medication: Atenolol	1.0	1.2	7.3	-0.9	1.5	1.1	-0.1	1.3	-0.1	2.7	0.4	0.7	-0.7	1.1	1.0	-0.6	1.0
Trunk fat mass	1.0	4.4	23.0	2.5	-0.1	-2.3	-2.6	-4.8	-0.6	-3.4	0.8	1.3	0.5	1.7	2.6	0.5	-0.7
Pain all over the body in last month	1.0	1.1	3.9	0.5	1.4	1.2	2.0	0.7	0.4	0.7	1.1	1.2	0.9	1.5	0.7	0.1	0.8
Alcohol intake versus 10 years previously	1.0	1.5	5.0	0.1	-0.4	-2.2	-0.7	-1.9	-1.8	-1.4	-0.4	-1.0	-1.9	-0.5	0.9	1.1	-0.5
Arm fat-free mass (right)	1.0	5.0	19.6	0.9	-2.0	-3.4	-3.6	-4.4	-1.4	-3.8	-1.2	-0.8	-1.2	-0.3	0.6	-0.7	-2.2
Worry too long after embarrassment	1.0	1.7	4.7	0.3	1.5	2.0	0.9	1.7	0.9	2.2	0.3	-2.0	0.4	0.7	-0.8	0.5	2.1
Health satisfaction	1.0	1.3	8.4	-1.4	0.9	0.7	-1.3	1.5	1.0	2.9	-0.4	-0.4	-0.8	-0.7	-0.1	-0.9	0.4
Family relationship satisfaction	1.0	1.2	4.4	-1.8	0.2	1.5	-0.8	1.5	-0.0	2.1	-0.4	-1.1	-1.2	0.5	-0.1	-1.1	0.7
Qualifications: NVQ or HND or HNC or equivalent	1.0	1.2	3.6	1.2	0.1	-1.1	-0.2	-1.3	0.2	-1.6	0.9	1.9	1.3	0.8	1.6	1.1	-0.6
Smoking status: Previous	1.0	1.6	4.7	0.1	-2.0	-2.2	-0.9	-1.8	-1.1	-1.5	-0.8	0.1	-0.5	-1.7	-0.1	-0.8	-1.6
Diabetes diagnosed by doctor	1.0	1.6	5.1	-1.5	-1.4	-1.7	-2.3	-0.9	-0.6	-0.9	-1.6	-1.3	-1.6	-0.6	-0.4	-0.6	-1.4
Fractured/broken bones in last 5 years	1.0	1.3	4.9	1.8	1.0	-0.1	1.7	-0.5	-2.2	1.1	1.1	0.8	1.2	-0.0	0.4	1.4	0.7
Bipolar Disorder or Schizophrenia	0.9	2.2	13.6	-2.2	0.1	1.6	-0.4	3.7	-1.0	2.1	-1.3	-1.4	-0.5	0.5	-0.8	-0.8	0.7
Alzheimer’s Disease (in mother)	0.9	1.0	3.8	0.9	0.6	-0.9	-1.5	-2.0	-0.1	-1.4	0.6	0.2	-0.4	1.6	1.5	-0.1	0.0
Age at First Birth	0.9	1.3	6.1	-1.7	-1.0	0.7	-0.1	1.6	0.1	-0.4	-0.8	-1.5	-0.5	0.2	-1.4	-2.5	-0.5
Ulcerative Colitis	0.9	1.3	4.4	0.1	1.3	1.6	1.2	1.7	-0.5	1.2	0.8	0.6	2.1	1.3	0.0	1.2	1.0
Pack years adult smoking proportion	0.9	1.4	4.9	-0.4	-0.5	-0.8	-1.3	-0.6	-2.0	0.3	-1.2	-2.2	-1.8	-0.9	-1.4	-0.4	-0.2
Trunk fat percentage	0.9	3.6	15.3	2.6	0.6	-1.4	-1.7	-3.9	-0.5	-2.7	1.3	1.6	1.0	2.3	2.8	1.0	-0.0
Maternal smoking around birth	0.9	1.3	3.1	1.4	1.4	1.0	0.3	-0.4	0.9	-0.7	1.6	1.1	0.9	-0.5	1.8	1.7	1.3
Chronic bronchitis/emphysema (father)	0.9	1.0	3.2	1.8	1.1	0.4	1.5	-0.4	-1.1	-1.2	1.2	0.9	1.4	0.3	0.6	0.6	0.6
Body mass index (BMI)	0.9	3.8	17.6	2.0	-0.5	-2.4	-2.6	-4.2	-1.5	-3.6	0.4	0.7	0.2	1.5	1.9	0.2	-0.9
Arm fat percentage (right)	0.9	3.4	14.9	2.5	0.5	-1.3	-1.7	-3.9	-0.3	-2.7	1.4	1.7	1.0	2.0	2.7	0.8	-0.0
Hip circumference	0.9	3.9	19.1	1.8	-0.7	-2.4	-3.2	-4.4	-0.5	-3.6	0.2	0.8	-0.2	0.8	2.1	0.1	-1.1
Father’s age at death	0.9	1.2	4.0	0.9	1.1	0.8	1.0	-0.1	1.1	0.8	1.1	1.4	1.6	2.0	0.8	1.1	0.9
Pulse rate	0.9	1.6	11.8	-0.4	0.4	0.5	2.3	1.0	3.4	1.4	0.8	0.8	0.9	-0.4	0.1	0.8	0.5
Arm fat mass (right)	0.9	3.5	18.7	2.4	0.1	-1.9	-2.2	-4.3	-0.4	-3.1	0.9	1.0	0.5	1.5	2.4	0.4	-0.5
Ever highly irritable/argumentative for 2 days	0.9	1.0	3.5	0.2	-0.1	-1.0	-1.9	-1.4	-1.3	-0.9	-0.3	-1.7	-1.0	-1.6	-0.1	-0.3	-0.2
Medication: Ventolin 100micrograms inhaler	0.9	1.2	4.2	-0.4	1.4	1.0	1.6	1.2	1.6	2.0	0.5	-0.8	-0.6	0.5	0.4	0.5	1.5
Body fat percentage	0.9	3.6	16.0	2.5	0.3	-1.5	-1.9	-4.0	-0.7	-2.9	1.2	1.7	0.9	2.2	2.6	0.7	-0.2
Number of full brothers	0.9	1.1	4.0	1.2	1.5	1.0	0.9	-0.8	0.7	0.1	1.7	1.4	0.3	0.0	2.0	-0.0	1.2
Pulse wave peak to peak time	0.9	1.0	4.6	0.6	1.1	1.6	-0.2	0.5	-2.2	-0.0	1.3	1.2	0.9	-0.5	1.0	0.4	1.2
Whole body fat mass	0.9	3.9	20.3	2.3	-0.1	-2.1	-2.5	-4.5	-0.8	-3.4	0.8	1.1	0.3	1.6	2.4	0.2	-0.6
Arm predicted mass (right)	0.9	4.8	20.4	1.0	-1.9	-3.4	-3.3	-4.5	-1.0	-3.9	-1.0	-0.5	-1.1	-0.4	0.8	-0.7	-2.1
Arm fat percentage (left)	0.9	3.6	15.6	2.6	0.6	-1.4	-1.8	-4.0	-0.3	-2.7	1.4	1.8	1.0	2.1	2.8	0.8	-0.0
Eye problems/disorders: Cataract	0.9	1.0	3.6	-0.3	0.4	0.9	-0.0	1.2	1.5	1.9	0.7	1.4	0.8	1.7	0.7	-0.1	0.5
Medication: Gliclazide	0.9	1.0	6.0	-0.8	-1.0	-0.1	-2.0	-0.5	-2.4	-0.8	-0.8	-0.2	-0.6	-0.6	0.3	-0.4	-0.6
Arm fat mass (left)	0.9	3.7	19.2	2.3	-0.0	-2.0	-2.3	-4.4	-0.5	-3.2	0.8	0.9	0.4	1.7	2.3	0.4	-0.6
Wears glasses or contact lenses	0.9	1.1	4.0	0.7	0.1	-1.6	-1.0	-1.3	-1.0	-0.1	0.8	2.0	0.6	0.4	1.9	-0.1	-0.6
Medication: Blood pressure	0.9	1.7	6.2	-2.5	-0.5	0.4	-0.4	2.3	0.1	1.5	-0.7	-0.4	-1.1	1.3	-0.9	-2.5	-0.4
Commuting to job workplace: Cycle	0.9	1.1	4.8	0.1	1.1	2.2	0.5	1.3	1.0	1.0	0.7	0.3	1.2	1.1	0.8	0.5	1.4
Cholesterol lowering medication	0.9	1.3	6.4	-1.1	0.7	1.6	0.2	2.5	-0.4	1.9	0.3	-0.1	0.5	1.8	-0.4	0.0	1.0
Intelligence (Savage-Jansen 2018)	0.8	2.4	6.1	-2.4	-1.7	-1.1	-2.4	0.2	-1.2	-0.1	-2.5	-1.5	-2.4	0.3	-1.1	-1.1	-1.5
Fasting Glucose	0.8	0.9	2.8	-0.3	-0.7	-1.0	-1.4	-1.6	-0.7	-1.2	-0.3	0.2	-0.9	0.6	0.6	-1.7	-1.0
Hand grip strength (left)	0.8	2.0	11.6	0.6	-1.6	-1.3	-0.7	-2.2	0.2	-3.4	-0.8	-0.8	-0.7	-2.1	-0.5	0.7	-1.3
Leg fat-free mass (left)	0.8	4.1	17.5	0.8	-1.6	-3.2	-3.4	-4.2	-0.1	-3.2	-0.7	-0.2	-1.5	-0.7	1.1	-0.7	-2.0
Supplements: Glucosamine	0.8	1.0	3.6	1.9	0.7	-0.0	-0.6	-1.3	-0.3	0.0	1.1	1.0	1.3	0.0	1.3	1.7	0.8
Leg predicted mass (left)	0.8	4.2	18.1	0.8	-1.6	-3.2	-3.4	-4.3	-0.1	-3.3	-0.7	-0.2	-1.4	-0.6	1.1	-0.7	-2.0
Financial difficulties in last 2 years	0.8	1.0	4.8	0.9	-0.1	-1.3	-0.3	-1.8	1.0	-2.2	0.6	0.1	-0.6	-1.4	0.9	0.4	-0.4
Diabetes (self-reported)	0.8	1.3	3.9	-1.3	-1.2	-1.3	-2.0	-0.8	-1.1	-1.2	-1.3	-1.2	-1.5	-0.7	-0.4	-0.8	-1.0
Fluid intelligence score	0.8	1.6	5.6	-1.7	-0.8	-0.4	-1.4	0.1	0.9	-0.3	-2.0	-2.3	-2.4	-0.4	-0.5	-1.0	-0.7
Weight	0.8	4.2	22.9	1.9	-0.7	-2.7	-2.9	-4.8	-0.4	-3.6	0.3	0.5	-0.2	1.0	1.9	0.0	-1.2
Impedance of arm (right)	0.8	3.8	9.2	0.2	2.4	2.7	2.8	2.3	3.0	2.9	1.7	1.4	0.9	0.6	1.0	1.3	2.2
Trunk fat-free mass	0.8	4.5	18.2	0.5	-2.0	-3.2	-3.4	-4.3	-0.6	-3.5	-1.1	-0.5	-1.4	-0.6	0.8	-0.9	-2.3
Medication: Paracetamol	0.8	1.3	6.0	1.1	-0.2	-2.4	-1.4	-2.5	0.2	-1.4	-0.3	-0.5	-0.5	-0.7	0.3	-0.1	-0.9
Whole body fat-free mass	0.8	4.7	19.3	0.7	-1.9	-3.4	-3.5	-4.4	-0.7	-3.5	-1.1	-0.6	-1.5	-0.7	0.8	-0.9	-2.3
Leg fat-free mass (right)	0.8	4.3	17.9	0.9	-1.8	-3.3	-3.1	-4.2	-0.2	-3.5	-0.8	-0.6	-1.4	-1.1	0.6	-0.6	-2.2
Mineral and other dietary supplements	0.8	1.1	3.2	-1.1	-0.6	-0.7	-1.3	0.2	-0.0	0.9	-1.6	-1.8	-1.4	0.2	-1.4	-1.1	-0.8
Whole body water mass	0.8	4.4	17.8	0.6	-1.9	-3.2	-3.4	-4.2	-0.6	-3.4	-1.0	-0.6	-1.4	-0.7	0.7	-0.9	-2.2
Leg predicted mass (right)	0.8	4.2	17.3	0.8	-1.8	-3.3	-3.0	-4.2	-0.2	-3.5	-0.8	-0.6	-1.4	-1.0	0.6	-0.7	-2.2
Medication: Bendroflumethiazide	0.8	1.2	6.8	-1.0	0.7	1.3	-0.1	1.5	0.5	1.8	0.3	0.2	0.3	2.6	0.5	-0.3	1.3
Basal metabolic rate	0.8	4.7	21.8	1.1	-1.6	-3.3	-3.4	-4.7	-0.6	-3.7	-0.7	-0.4	-1.2	-0.4	1.1	-0.6	-2.1
Arm fat-free mass (left)	0.8	4.0	16.6	0.8	-1.8	-2.9	-3.0	-4.1	-1.2	-3.6	-1.1	-0.7	-0.9	-0.0	0.7	-0.6	-2.0
Ever depressed for a whole week	0.8	1.0	6.0	-0.3	-0.1	-0.1	-0.7	0.0	-0.7	1.6	-0.4	-1.1	-1.7	-2.5	-0.3	-0.6	-0.1
Alcohol drinker status: Previous	0.8	0.9	4.2	0.3	0.9	0.7	0.5	0.2	2.0	-0.1	-0.4	-2.0	-0.0	1.2	-0.5	1.1	0.7
Arm predicted mass (left)	0.8	4.1	16.0	0.6	-1.9	-3.0	-3.3	-4.0	-1.3	-3.4	-1.2	-0.8	-1.2	0.1	0.6	-0.7	-2.1
Crohns Disease (2017)	0.7	1.5	5.8	1.5	1.1	0.8	1.3	-1.0	0.6	-1.1	1.0	-0.2	1.3	1.7	0.6	2.4	1.3
Ovarian Cancer	0.7	1.0	4.2	-0.4	-0.1	0.1	1.2	1.2	-0.9	-0.1	-0.6	-1.5	-0.8	-1.3	-2.1	-1.1	-0.4
Type 2 Diabetes (T2D) (2018)	0.7	1.3	3.5	-0.1	-0.8	-1.8	-1.9	-1.9	-1.4	-1.5	-0.9	-0.7	-1.1	-0.5	0.0	-0.0	-1.0
Diverticular disease/diverticulitis (self-reported)	0.7	0.8	3.5	-0.0	-0.8	-0.1	0.1	-0.2	0.6	-0.4	-0.2	-0.9	-0.8	-1.6	-1.6	-1.9	-0.6
Waist circumference	0.7	2.4	11.9	1.2	-0.5	-2.3	-2.2	-3.5	0.1	-2.6	0.1	0.9	0.0	1.1	1.6	-0.2	-1.1
Number of incorrect matches in round	0.7	1.1	4.8	-1.2	0.3	1.6	1.5	2.2	0.1	0.9	0.2	-0.2	0.7	1.5	-0.9	0.0	1.0
Hayfever/allergic rhinitis (self-reported)	0.7	0.9	3.0	-0.3	-0.0	0.4	1.0	0.2	1.7	0.2	1.0	1.7	-0.1	1.4	1.7	0.2	0.6
Neuroticism score	0.7	1.5	5.9	-1.2	-0.1	0.1	0.3	1.6	-0.5	1.6	-1.4	-2.4	-0.8	-1.0	-2.1	-0.7	-0.4
Worrier / anxious feelings	0.7	1.4	5.8	-2.0	-0.7	0.3	1.0	2.4	-0.3	0.9	-1.1	-1.5	-0.4	0.2	-2.0	-1.0	-0.5
Qualifications: A levels/AS levels or equivalent	0.7	1.6	4.8	-1.0	-1.7	-1.7	-2.2	-1.0	1.1	-0.9	-1.5	-0.7	-1.4	-1.3	-0.7	-0.8	-1.6
Medication: Ibuprofen (e.g. Nurofen)	0.7	0.9	3.6	0.7	-0.5	-1.4	-0.7	-1.9	-0.7	-1.2	-0.6	-0.2	-0.6	-1.6	-0.1	0.1	-1.0
Depression (self-reported)	0.7	0.8	3.8	-1.9	-0.7	0.0	0.8	1.4	-0.6	-0.2	-0.7	-0.4	-0.7	0.1	-1.2	-1.3	-1.0
Impedance of arm (left)	0.7	3.2	9.7	0.1	2.1	2.4	2.2	2.3	2.7	3.1	1.4	1.2	0.9	0.8	0.7	1.2	1.9
Trunk predicted mass	0.7	4.2	16.8	0.5	-1.9	-3.1	-3.4	-4.1	-0.7	-3.3	-1.1	-0.5	-1.4	-0.6	0.8	-1.0	-2.2
Seen doctor (GP) for nerves, anxiety, tension or depression	0.7	1.1	3.2	1.3	1.4	0.7	1.6	-0.5	-0.1	0.5	1.8	1.5	0.5	-1.1	1.3	0.6	0.9
Birth weight of first child	0.7	1.3	3.1	1.7	1.6	1.6	0.9	-1.1	0.1	-0.1	1.6	1.1	0.9	0.4	1.6	0.6	1.4
Peak expiratory flow (PEF)	0.7	1.5	8.2	1.6	-0.3	-1.4	-0.1	-2.5	0.1	-2.9	-0.2	-0.0	0.5	-0.4	0.5	1.5	-0.7
Headache pain in last month	0.7	1.2	4.7	1.0	-0.3	-2.1	-1.7	-2.2	0.8	-0.6	-0.3	0.3	-1.2	-0.9	0.7	-0.1	-1.0
Qualifications: College or University degree	0.7	2.1	6.4	-1.4	-1.5	-0.8	-2.5	-0.4	-0.2	-0.8	-1.9	-2.2	-1.9	-1.4	-1.4	-1.3	-1.1
Mouth/teeth dental problems: Loose teeth	0.7	0.9	6.2	-0.5	0.3	-0.1	0.8	0.7	2.5	0.5	1.1	1.5	-0.4	-0.9	0.2	-1.0	-0.2
Had major operations	0.7	0.8	2.9	1.0	1.1	0.5	-0.3	-0.4	0.3	1.7	0.9	0.2	0.9	0.5	1.0	1.1	1.3
Supplements: Vitamin C	0.7	0.8	2.7	-1.6	-0.9	-0.1	1.4	1.6	-1.0	0.5	-0.5	0.3	-0.5	0.6	-0.5	-0.7	-1.0
Friendships satisfaction	0.7	0.9	2.3	-0.1	1.0	1.4	1.0	1.2	1.3	1.5	0.3	-0.5	0.7	0.6	0.3	0.9	1.1
Medication for cholesterol	0.7	1.1	4.1	1.3	-0.1	-1.4	-0.2	-2.0	0.3	-0.8	0.0	0.8	0.1	-1.8	1.1	1.7	-0.4
Osteoarthritis (self-reported)	0.7	0.9	5.6	0.8	1.0	0.6	0.1	-0.5	0.7	0.6	1.1	1.4	-0.0	0.6	2.4	0.1	1.3
Guilty feelings	0.7	1.0	5.6	-0.2	0.1	0.5	0.2	0.3	-0.9	1.2	-0.9	-2.4	-0.5	-1.3	-2.0	-0.3	-0.2
Heart attack/myocardial infarction (self-reported)	0.7	0.9	4.6	-0.1	1.5	0.8	1.0	0.8	0.4	2.1	0.7	-0.3	-0.3	0.7	1.0	0.1	1.6
Heart disease (siblings)	0.7	0.9	2.9	0.9	0.7	0.6	0.4	0.2	-0.5	1.2	0.9	1.5	1.7	1.7	0.8	0.5	0.7
Pack years of smoking	0.7	1.0	3.5	-0.4	-0.4	-0.7	-1.2	-0.3	-1.9	0.6	-1.0	-1.9	-1.5	-0.6	-1.3	-0.7	-0.2
Schizophrenia (2018)	0.6	1.2	6.2	-0.9	0.9	2.2	-0.1	2.5	-0.2	1.5	-0.2	-0.8	-0.1	0.2	0.3	-0.2	1.4
Schizophrenia vs Biploar Disorder	0.6	0.8	2.6	1.6	1.1	0.6	1.2	-1.1	-0.3	-0.1	1.4	0.6	1.4	-0.1	0.5	0.4	0.9
Alzheimer’s Disease (in father)	0.6	0.6	2.1	1.0	0.4	-0.6	-0.7	-1.3	0.4	-1.3	0.2	-0.5	1.2	-0.1	-0.1	1.5	-0.2
Neuroticism (2016)	0.6	0.9	2.5	-0.2	1.4	1.5	1.1	1.2	0.2	1.4	0.7	-0.7	0.0	0.3	-0.1	0.5	1.6
Townsend deprivation index at recruitment	0.6	0.8	4.0	0.7	0.1	-0.6	1.6	-0.6	1.4	1.0	0.1	-0.2	-0.7	-2.0	-0.6	0.1	-0.3
Average weekly fortified wine intake	0.6	0.7	4.0	1.8	0.5	-0.4	-0.1	-2.0	-0.4	-0.5	0.7	1.0	0.6	-0.1	0.9	0.3	0.1
High blood pressure (mother)	0.6	0.9	3.6	-0.2	0.0	0.4	-1.1	0.1	-1.6	1.7	-0.8	0.3	0.2	1.9	-0.5	-1.0	-0.6
Hair/balding pattern: Pattern 2	0.6	0.7	2.6	0.3	-0.6	-1.6	-0.2	-1.6	-0.7	-0.2	-1.2	-1.3	-0.9	-0.2	-0.7	0.3	-0.9
Allergy	0.6	1.3	8.1	0.3	-0.7	-0.5	-0.4	-0.2	-2.8	-0.2	-1.2	-1.4	0.3	-1.1	-2.2	-0.2	-1.1
Medication: Simvastatin	0.6	0.9	2.6	-1.4	0.1	0.9	-1.4	1.4	-1.0	1.6	0.1	0.1	-0.5	0.3	0.4	-1.5	0.7
Illnesses of siblings	0.6	0.8	3.2	0.7	0.5	-0.4	-1.8	-0.8	-0.1	-1.5	0.1	-1.5	-0.6	-1.2	0.0	0.9	0.4
Illnesses of mother	0.6	0.7	5.9	-1.0	-0.7	0.2	0.5	0.8	0.9	-0.8	-0.0	-0.2	-0.6	-2.4	-0.6	-0.3	-0.2
Birth weight	0.6	1.3	4.2	2.0	1.3	0.4	-0.2	-1.8	-0.9	-0.0	1.2	1.1	1.5	1.3	1.6	-0.2	0.5
Chronic bronchitis/emphysema (mother)	0.6	0.7	2.5	1.6	1.3	-0.2	1.0	-0.6	1.3	-0.1	1.1	-0.2	1.0	-0.2	0.2	0.5	0.7
High blood pressure (siblings)	0.6	0.8	3.2	-1.2	-0.8	0.8	1.8	0.9	0.1	1.2	-0.6	0.5	-0.3	-0.0	-1.1	-1.4	-0.5
Shortness of breath walking on level ground	0.6	0.8	3.4	-1.3	-0.6	-0.7	-0.8	0.4	1.0	0.4	-0.9	-1.0	-1.9	-0.4	-0.0	-1.0	-0.8
Medication for pain relief, constipation, heartburn	0.6	1.1	4.4	-0.3	0.6	2.1	2.0	1.8	0.5	0.3	0.3	-0.6	1.0	0.3	-0.9	0.9	1.0
Medication: Allopurinol	0.6	0.8	3.0	-0.2	-1.0	-0.8	-0.7	-0.5	0.4	-0.1	-1.1	-1.6	-0.5	-1.0	-1.7	-0.4	-0.9
Alcohol intake frequency.	0.6	1.3	5.2	1.1	0.9	0.1	1.1	-1.8	0.5	-1.4	0.5	-0.7	-0.9	0.8	1.6	2.3	1.2
Medication: Aspirin	0.6	0.8	2.8	-1.2	-0.4	-0.5	-1.2	1.0	0.2	1.7	-0.0	1.3	-0.5	0.1	0.9	-1.2	-0.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.6	0.7	2.4	-1.2	-0.3	-0.4	-1.4	0.7	0.4	0.8	-1.2	-1.2	-1.5	-0.6	-0.5	-0.1	-0.1
Forced expiratory volume in 1-second (FEV1), predicted	0.6	1.3	7.5	0.2	-0.5	-1.0	-0.7	-1.7	0.6	-1.7	-0.4	-0.9	-1.2	-2.7	-0.8	-0.5	-1.1
Average weekly red wine intake	0.6	0.9	4.3	1.1	-0.0	-1.0	-2.1	-1.6	-0.4	-0.2	0.3	1.1	0.8	0.3	1.1	-0.4	-0.4
Number of self-reported non-cancer illnesses	0.6	1.1	6.2	-0.3	0.2	0.6	0.6	0.4	2.5	0.8	0.6	1.2	0.3	1.9	1.3	0.2	0.9
Eye problems/disorders: Glaucoma	0.6	0.7	2.3	-1.2	-1.1	-0.4	-0.9	0.5	0.2	0.1	-1.1	-0.5	-1.5	-0.7	-0.7	-0.6	-1.1
Neuroticism (Nagel 2018)	0.5	1.2	6.5	-0.7	0.8	1.0	1.2	2.3	1.1	2.5	-0.4	-0.7	0.3	0.4	-0.7	0.3	0.5
Coronary Artery Disease (CAD)	0.5	0.6	2.4	-0.9	-0.0	1.1	0.4	1.5	-0.8	0.5	-0.9	-0.6	-0.7	1.2	-0.2	0.1	0.3
Primary Biliary Cirrhosis	0.5	0.7	2.3	0.4	0.4	0.7	0.7	0.7	1.3	1.4	0.8	1.5	1.4	0.7	0.3	-0.3	0.2
Tanning	0.5	6.0	11.5	-2.8	-3.2	-2.8	-1.0	-0.4	-2.1	-2.9	-3.4	-1.8	-3.2	-2.3	-2.2	-2.1	-3.4
Angina	0.5	0.7	2.4	0.1	0.6	1.2	1.5	1.1	0.6	1.4	0.7	0.5	0.1	0.5	0.5	-0.3	1.2
Hand grip strength (right)	0.5	1.5	9.1	0.6	-1.3	-1.1	-0.9	-2.1	0.2	-3.0	-0.8	-0.8	-0.4	-0.7	-0.1	1.0	-1.0
Fed-up feelings	0.5	0.9	2.9	-0.5	-0.6	-1.7	-0.8	-0.6	0.6	0.4	-1.2	-1.2	-0.6	-1.0	-1.2	-0.7	-1.4
Age when periods started (menarche)	0.5	1.3	6.0	-0.5	-0.1	0.0	1.0	1.9	1.7	2.5	-0.1	0.8	1.5	-1.2	-0.5	0.6	0.1
Heel bone mineral density (BMD) T-score, automated (left)	0.5	1.1	3.5	1.1	-0.7	-1.2	-1.9	-1.9	-1.3	-1.4	-0.1	0.3	0.6	1.0	-0.1	-0.0	-1.3
Alcohol usually taken with meals	0.5	0.9	4.3	0.2	-1.1	-0.6	-2.1	-1.4	-1.5	-1.2	-0.4	0.1	-0.1	0.6	0.6	0.4	-0.3
Heart attack	0.5	0.7	3.5	-0.0	1.3	0.6	1.0	0.6	0.3	1.9	0.5	-0.7	-0.4	0.4	0.6	-0.0	1.4
Medication: Ramipril	0.5	0.6	2.2	0.9	1.5	0.5	-0.2	-0.2	0.2	1.0	0.9	1.0	0.7	-0.2	1.0	0.5	1.0
Time employed in main current job	0.5	0.5	1.7	-0.2	-0.6	0.0	-1.1	-0.5	-1.1	-0.8	-0.6	-1.3	0.8	-0.4	-1.0	0.7	-0.0
Falls in the last year	0.5	0.7	1.7	1.0	0.9	-0.7	-0.7	-1.0	-0.7	1.3	0.8	0.8	0.2	0.3	1.2	0.8	0.7
Hair/balding pattern: Pattern 3	0.5	0.8	4.6	0.5	-0.0	-0.2	0.1	-1.1	-0.7	-2.1	0.7	1.3	0.1	0.2	1.6	0.7	0.0
Medication: Cholesterol lowering	0.5	0.8	6.0	-0.3	0.6	1.1	-0.4	1.1	-0.4	2.4	0.4	0.6	0.6	0.5	0.3	-0.5	0.9
Medication for cholesterol, blood pressure or diabetes	0.5	0.9	5.0	-0.1	-0.7	-0.9	0.0	-0.9	1.3	-2.2	-0.6	-1.3	-0.8	-0.3	-0.6	0.2	-0.9
Forced vital capacity (FVC), Best measure	0.5	2.0	5.2	-1.2	-2.1	-1.8	-0.6	-0.5	0.1	-1.9	-1.9	-1.4	-1.2	-1.2	-1.6	-0.7	-2.3
Neck or shoulder pain in last month	0.5	0.7	2.7	0.5	0.0	-0.7	-1.4	-0.9	-0.9	0.2	-0.4	-1.6	-1.2	-0.7	-0.4	-1.2	0.0
Angina (self-reported)	0.5	0.7	2.2	0.0	0.7	1.3	1.5	1.2	0.5	1.5	0.6	0.3	0.0	0.4	0.3	-0.3	1.3
Medication: Ibuprofen	0.5	0.5	3.5	0.3	-0.4	-0.6	0.1	-1.1	0.2	-1.0	-0.3	-0.4	-0.7	-1.9	-0.5	-0.9	-0.6
Medication: Omeprazole	0.5	0.6	2.1	0.1	0.5	0.9	0.7	0.9	0.0	1.4	0.2	0.1	0.2	1.1	0.2	1.3	1.0
Leg pain on walking	0.5	0.6	2.8	0.6	0.9	0.1	0.1	0.2	-0.3	1.2	0.9	0.5	0.8	-0.3	0.8	1.7	0.7
Medication: Aspirin	0.5	0.7	2.6	-0.9	-0.1	-0.4	-1.0	0.8	0.7	1.5	0.4	1.6	0.0	0.2	0.9	-1.0	-0.2
Commuting to job workplace: Public transport	0.5	0.6	3.3	-1.2	-0.4	-0.2	-0.8	-0.1	1.3	0.3	-0.9	-0.9	-1.8	-0.3	0.2	-0.4	-0.1
Medication: Paracetamol	0.5	0.7	2.9	1.1	-0.1	-1.3	0.1	-1.7	1.3	-1.1	0.6	0.3	0.0	-1.1	0.5	-0.3	-0.4
Number of operations (self-reported)	0.5	0.7	2.5	0.2	1.0	0.8	0.5	0.7	-0.3	1.1	0.6	0.1	0.9	1.2	0.6	1.3	1.6
Unable to work because of sickness or disability	0.5	0.6	2.5	1.4	1.6	0.3	0.1	-0.6	0.1	0.8	1.1	-0.2	0.2	-1.1	0.1	0.6	1.0
Major Depression (MDD)	0.4	0.5	1.3	-0.6	0.8	-0.3	0.7	0.9	0.5	0.9	0.4	0.4	-0.9	-0.1	1.1	0.7	0.7
Mean Putamen Volume	0.4	0.5	1.6	-0.3	-1.0	-1.2	-1.3	-0.8	0.9	0.2	-0.6	-0.4	-0.4	-0.6	-0.2	-0.2	-0.6
HbA1C	0.4	0.4	2.2	-0.3	-0.7	-0.2	-1.5	-0.3	-0.4	0.6	-0.5	0.8	-0.5	-0.2	0.7	-0.8	-0.5
Triglycerides	0.4	0.6	2.6	0.0	-0.7	-1.2	-1.6	-1.6	0.1	0.1	-0.6	0.6	-0.4	0.5	0.3	-0.5	-1.0
Type 2 Diabetes (T2D) (2012)	0.4	0.5	1.4	-1.2	-0.5	0.4	-0.8	0.5	-0.4	-0.0	-0.6	0.3	-1.1	1.1	1.1	-0.8	-0.1
Heel T-Score	0.4	3.1	9.7	-0.2	-2.2	-2.1	-2.3	-1.8	-2.3	-3.1	-1.9	-1.1	-0.5	0.5	-1.5	-0.5	-2.6
Systolic blood pressure, automated reading	0.4	1.1	3.0	-1.7	-1.6	-0.1	-0.8	1.3	-1.1	0.4	-1.1	-0.2	0.2	1.3	-1.0	-1.6	-0.9
Medication for hormone replacement therapy	0.4	0.4	2.9	-0.3	0.3	0.8	0.6	0.7	0.0	0.2	-0.1	-0.9	0.3	1.7	-0.7	-0.8	0.3
Vitamin and mineral supplements	0.4	0.6	4.3	0.6	0.7	0.6	-2.1	-0.7	0.4	0.2	-0.0	-0.9	-0.6	0.5	0.4	0.3	0.9
Medication: Metformin	0.4	0.5	3.2	-0.6	-0.6	-0.5	-1.8	-0.8	-0.4	-0.6	-0.7	0.1	-0.7	-0.1	0.8	0.2	-0.6
Severe depression (siblings)	0.4	0.4	2.4	0.2	0.6	0.4	0.1	-0.5	-0.6	0.4	0.7	1.0	-0.1	1.1	1.5	-0.5	0.5
Bilateral oophorectomy (both ovaries removed)	0.4	0.4	1.4	-0.2	0.8	1.2	0.9	0.8	-0.7	0.0	0.2	-0.2	0.1	1.1	0.2	0.6	0.9
Hayfever, allergic rhinitis or eczema	0.4	1.0	3.7	0.3	0.7	0.1	-0.3	-0.5	1.2	-0.2	1.2	1.8	0.5	1.2	1.9	1.0	0.8
Multivitamins +/- minerals	0.4	0.6	4.5	-0.0	-0.3	-0.0	2.1	0.5	-0.8	-0.3	0.4	0.6	1.3	-0.1	-0.5	0.5	-0.3
Forced vital capacity (FVC)	0.4	1.5	5.2	0.2	-1.3	-1.9	-1.2	-2.0	-0.5	-2.3	-1.3	-0.8	-0.6	-0.9	-0.6	0.4	-1.7
Heel bone mineral density (BMD) T-score, automated (right)	0.4	0.8	3.0	1.3	-0.3	-0.9	-1.2	-1.6	-1.7	-0.6	-0.0	0.0	0.8	0.8	-0.2	0.7	-0.9
Ever unenthusiastic/disinterested for a whole week	0.4	0.5	2.2	0.2	0.8	0.9	0.6	0.8	-0.4	1.5	0.5	-0.4	0.3	-0.5	0.4	0.9	1.1
Forced expiratory volume in 1-second (FEV1)	0.4	1.5	5.6	0.8	-1.1	-1.8	-1.2	-2.2	-0.8	-2.4	-0.9	-0.2	0.0	-0.3	-0.2	0.8	-1.6
Medication: Lansoprazole	0.4	0.5	1.2	0.1	-0.9	-1.1	-1.0	-1.0	0.3	-0.4	-0.8	0.2	-0.6	0.4	-0.1	-0.6	-1.1
Breastfed as a baby	0.4	0.5	3.0	0.7	0.3	-1.1	-0.5	-0.8	-1.7	-0.0	0.6	0.8	0.9	0.1	0.4	0.7	-0.2
Hair/balding pattern: Pattern 4	0.4	1.0	4.4	-1.4	-1.4	-0.1	1.2	1.5	0.5	-0.1	-0.7	0.1	-0.0	0.1	-1.2	-2.1	-0.8
Mouth/teeth dental problems: Bleeding gums	0.4	0.5	1.7	-1.1	0.6	0.8	-0.1	1.3	-0.1	1.2	-0.2	-0.6	-0.0	0.9	0.3	-0.2	0.5
Glaucoma (self-reported)	0.4	0.4	1.1	-0.8	-1.1	-0.8	-0.8	-0.0	-0.6	-0.3	-0.8	0.1	-0.8	-0.6	-0.3	0.0	-1.0
Exposure to tobacco smoke outside home	0.4	0.5	1.8	0.8	0.2	-1.1	-0.8	-1.3	-1.4	-0.8	0.1	-0.8	0.1	-0.7	-0.2	0.1	-0.3
Seen a psychiatrist for nerves, anxiety, tension or depression	0.4	0.5	2.0	-1.0	0.5	0.7	1.4	1.4	-0.8	0.6	-0.1	0.5	0.1	0.2	-0.4	-0.7	-0.2
Reason for reducing amount of alcohol drunk: Health precaution	0.4	0.5	2.0	-0.5	-0.5	-0.1	0.7	0.6	-1.4	1.4	-0.4	0.1	0.1	-0.6	-0.9	0.3	-0.4
Eye problems/disorders: None of the above	0.4	0.5	1.2	1.1	0.9	0.2	0.8	-0.7	-1.1	-0.8	0.7	-0.2	0.6	0.3	0.6	0.8	0.9
Medication: Blood pressure	0.4	0.7	6.1	-0.2	0.7	0.8	0.7	1.2	-0.7	2.5	0.2	0.5	0.3	-0.0	-0.1	0.1	0.9
Pulse rate, automated reading	0.4	1.3	5.2	-1.3	0.2	0.6	2.3	2.1	1.8	1.8	0.5	0.7	-0.1	0.2	-0.1	-0.1	0.6
Suffer from ‘nerves’	0.4	0.7	1.8	0.4	1.3	1.4	0.7	0.8	-0.2	1.1	0.3	-1.4	0.5	0.7	-0.7	0.2	1.1
Overall health rating	0.4	0.8	6.5	-0.4	1.5	0.6	-0.3	1.1	-0.2	2.5	0.1	-0.4	-0.2	0.4	0.1	0.4	1.1
Age at last live birth	0.4	0.5	1.8	-0.6	-0.8	-0.6	-0.6	-0.0	-1.0	0.0	-0.8	-0.1	0.1	0.4	-0.9	-1.3	-1.2
Mood swings	0.4	0.8	2.5	-0.6	-0.7	-1.6	-0.1	-0.6	-0.5	-0.2	-1.0	-1.3	-1.2	-0.8	-0.8	-0.7	-1.1
Long-standing illness, disability or infirmity	0.4	0.7	2.5	0.1	0.4	-0.6	-1.0	-0.3	0.1	1.2	0.4	1.0	0.2	1.5	1.6	0.7	0.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.4	0.4	1.5	0.7	0.7	0.6	1.0	0.3	-1.2	0.7	0.3	-0.4	0.6	-0.0	-0.2	0.9	0.8
Breast cancer (self-reported)	0.4	0.5	2.0	0.6	-0.1	-0.5	-1.0	-1.0	-1.4	-0.5	0.6	0.2	0.5	1.0	0.9	-0.1	0.3
Illnesses of father: None of the above (group 1)	0.4	0.5	1.2	0.7	0.2	-0.9	-0.0	-1.1	-0.5	-0.9	-0.5	-0.5	-0.9	-0.8	0.8	1.0	-0.8
Mother’s age at death	0.4	0.5	1.8	-0.2	0.3	0.8	-0.1	0.9	0.9	1.3	0.8	0.2	0.3	-0.7	-0.3	-1.0	0.6
Alcohol drinker status: Never	0.4	0.5	3.2	-0.5	-0.3	0.2	1.0	-0.2	0.5	-0.1	0.6	1.8	-0.3	0.5	1.3	-0.7	-0.1
Deep venous thrombosis (DVT) (self-reported)	0.4	0.5	1.3	-1.1	-1.1	-0.2	-0.3	0.2	0.8	-0.1	-0.7	0.2	-1.1	0.3	-0.4	-1.1	-0.9
Impedance of whole body	0.4	2.2	6.6	0.1	1.7	2.3	2.6	2.1	1.7	2.2	1.0	0.8	1.0	0.7	0.1	1.2	1.6
Breast Cancer	0.3	0.7	3.2	-0.6	-0.3	0.7	1.3	1.5	1.8	1.1	-0.2	-0.5	-0.1	-0.3	-1.0	0.5	0.3
LDL Cholesterol	0.3	0.5	2.0	-0.2	0.4	0.8	0.8	1.2	0.6	1.4	0.7	0.8	1.0	-0.3	-0.1	-0.3	0.2
Respiratory disease	0.3	0.7	3.2	-1.0	0.0	-0.1	-0.2	0.3	1.1	0.7	-1.0	-1.8	-1.5	0.9	-0.2	0.5	0.6
Neuroticism	0.3	0.6	4.1	-0.4	0.2	0.2	0.2	1.0	-0.0	2.0	-0.5	-1.4	-0.3	-0.8	-1.0	-0.2	0.0
Frequency of depressed mood in last 2 weeks	0.3	0.4	2.5	-1.5	-0.0	0.2	0.4	1.6	1.0	-0.0	-0.1	0.2	-0.1	0.5	0.2	-0.2	-0.1
Relative age of first facial hair	0.3	0.6	2.6	-0.4	-0.4	0.5	0.8	1.4	-0.1	0.8	-0.7	-1.3	-0.2	-0.0	-1.6	-0.7	-0.0
Other serious medical condition/disability diagnosed by doctor	0.3	0.4	1.5	-1.2	-0.6	-0.3	0.2	0.7	0.8	-0.2	0.2	1.2	-0.1	0.6	0.6	-1.0	-0.4
Ever had hysterectomy (womb removed)	0.3	0.4	2.3	-0.6	0.1	0.3	0.5	0.7	1.5	0.6	0.4	0.4	-0.4	-0.7	0.7	-0.1	0.5
Medication: Co-codamol	0.3	0.4	1.5	0.2	0.2	-1.1	-0.3	-1.0	-0.3	-0.2	-0.0	0.5	0.4	0.9	0.7	1.2	-0.2
Relative age voice broke	0.3	0.5	3.1	0.2	-0.2	0.2	1.8	0.7	-0.4	0.3	-0.0	-0.6	1.2	0.3	-1.3	-0.1	-0.2
Qualifications: CSEs or equivalent	0.3	0.5	1.8	1.3	0.8	-0.6	0.6	-1.2	0.5	-0.4	0.5	0.3	-0.0	-0.6	0.7	0.7	0.3
Impedance of leg (left)	0.3	1.4	5.0	0.6	1.4	1.8	2.2	1.2	0.3	1.1	0.7	0.5	1.4	0.7	-0.2	1.4	1.4
Asthma	0.3	0.5	2.4	-0.5	-0.4	-0.9	0.2	-0.4	0.6	0.2	-1.0	-1.5	-1.5	0.1	-0.4	0.6	0.0
Forced expiratory volume in 1-second (FEV1), Best measure	0.3	0.9	2.9	-0.3	-1.5	-1.3	-0.7	-0.9	-0.1	-1.7	-1.1	-0.6	-0.6	-0.5	-0.7	-0.0	-1.6
Exposure to tobacco smoke at home	0.3	0.3	1.2	-0.3	-0.3	-1.1	-0.1	-0.2	-0.1	-0.4	-0.5	-0.4	-0.6	-0.6	-0.8	-1.0	-0.7
Loud music exposure frequency	0.3	0.3	2.7	0.2	0.4	0.0	-0.8	0.2	-1.6	0.9	-0.2	-0.2	0.3	0.2	-0.6	-0.2	0.2
Blood clot in the leg (DVT)	0.3	0.4	1.1	-1.0	-0.8	0.1	-0.2	0.3	1.1	0.0	-0.5	0.3	-1.0	0.3	-0.1	-1.0	-0.7
Wheeze or whistling in the chest in last year	0.3	0.5	1.7	0.4	1.1	-0.3	-0.3	-0.3	-0.1	1.3	0.5	-0.4	-0.6	-0.1	1.0	1.1	1.1
Number of full sisters	0.3	0.3	1.2	-0.0	0.6	0.5	0.1	0.1	0.5	0.2	0.3	-1.1	-0.8	-1.1	-0.1	0.1	1.0
Chest pain or discomfort	0.3	0.4	2.8	-0.4	-0.1	-0.5	-0.5	-0.2	-0.6	0.3	-0.3	-0.7	-1.7	-0.8	0.8	-0.5	0.1
Handedness (chirality/laterality): Left-handed	0.3	0.4	1.4	-0.1	0.6	0.6	0.5	0.4	-0.3	1.2	0.5	0.9	0.1	-0.3	1.0	0.1	0.8
Loneliness, isolation	0.3	0.4	1.8	-0.5	0.2	0.2	1.0	0.8	0.7	0.6	-0.5	-1.3	-0.1	-0.2	-1.2	-0.2	-0.2
Ever had stillbirth, spontaneous miscarriage or termination	0.3	0.3	1.1	0.4	0.8	0.1	-0.4	-0.1	0.6	-0.1	0.3	0.3	0.4	-0.3	1.1	1.0	0.5
Asthma (self-reported)	0.3	0.5	2.3	-0.5	-0.3	-0.8	0.1	-0.3	0.8	0.5	-1.0	-1.3	-1.5	0.3	-0.2	0.5	0.1
Average weekly champagne plus white wine intake	0.3	0.4	1.7	0.5	0.6	1.0	0.1	-0.0	-0.4	1.2	0.2	0.1	0.4	1.3	0.2	0.1	0.7
Financial situation satisfaction	0.3	0.4	1.2	0.6	1.0	-0.1	-0.1	-0.6	1.1	1.0	0.8	0.6	0.3	-0.1	0.7	0.1	0.2
Supplements: Fish oil (including cod liver oil)	0.3	0.4	1.4	0.8	-0.3	-0.4	1.0	-0.4	-0.9	-0.5	0.4	1.2	1.0	-0.0	0.1	0.8	-0.5
Supplements: Calcium	0.3	0.4	1.3	-0.8	0.6	0.6	0.9	1.1	-0.6	0.3	0.4	0.0	-0.1	-0.4	0.7	-0.0	0.9
Prostate Cancer	0.2	0.2	1.8	0.2	-0.1	0.6	1.3	0.3	0.2	-0.5	0.1	-0.5	0.3	0.4	-0.5	-0.1	0.3
HDL Cholesterol	0.2	0.3	1.2	0.4	0.4	-0.3	1.1	-0.0	-0.9	-0.5	0.5	-0.1	0.7	0.3	0.1	1.0	0.1
Blood Eosinophil Count	0.2	1.2	5.1	0.7	0.1	-0.3	0.8	-0.6	1.4	-2.2	-0.5	0.1	1.9	0.6	-1.3	2.0	-0.7
Blood Red Count	0.2	2.1	8.4	1.1	0.3	-1.3	-1.6	-2.5	-1.0	-2.6	-0.9	-0.8	-0.5	2.9	0.6	1.5	-0.5
Smoking Status	0.2	0.5	1.8	-0.4	-1.1	-1.4	-0.2	-0.8	-0.0	-0.9	-0.4	0.0	-0.7	-1.2	0.3	-0.0	-0.9
Allergy or Eczema	0.2	0.6	2.0	0.3	0.1	-0.4	-0.8	-1.2	0.2	-0.7	0.5	1.1	0.2	1.2	1.4	1.2	0.4
Number of treatments/medications taken	0.2	0.4	2.2	-0.4	-0.1	-0.3	0.6	0.3	1.4	0.7	0.1	0.2	-0.5	-0.1	0.1	-1.5	-0.1
Impedance of leg (right)	0.2	1.2	3.2	0.4	1.4	1.7	1.8	1.1	0.4	1.4	0.7	0.8	0.9	1.1	0.4	1.2	1.4
Taking other prescription medications	0.2	0.3	1.7	-0.1	-0.1	-0.1	0.7	0.4	1.2	1.3	0.1	0.4	-0.4	0.4	0.1	-0.5	0.4
High blood pressure	0.2	0.7	4.1	-1.0	0.2	0.6	0.4	1.6	-0.5	2.0	0.1	0.5	0.3	0.2	-0.6	-0.8	0.5
Length of working week for main job	0.2	0.2	0.7	-0.2	-0.3	-0.6	-0.1	-0.4	0.2	-0.8	-0.7	-0.4	-0.5	0.7	0.2	0.6	-0.2
Gout (self-reported)	0.2	0.3	1.9	-0.0	-0.9	-0.8	-0.0	-0.7	1.4	-0.3	-0.2	0.3	-0.2	-0.4	-0.1	0.4	-0.8
Hypothyroidism/myxoedema (self-reported)	0.2	0.4	1.1	-0.6	-0.9	-0.4	0.0	-0.4	-0.3	-1.0	-0.7	0.5	-1.0	0.3	0.5	-0.9	-0.3
Heart disease (mother)	0.2	0.2	1.2	-0.4	-0.4	-0.5	-1.1	-0.5	-0.4	0.3	-0.8	0.0	-0.1	0.5	0.2	-0.1	-0.2
Comparative height size at age 10	0.2	1.0	5.7	1.2	0.9	0.1	-1.2	-2.4	0.7	-0.8	0.8	0.7	-0.5	-0.6	1.7	0.4	0.2
Knee pain experienced in last month	0.2	0.3	1.6	-0.3	0.1	0.1	0.9	0.8	1.3	0.8	0.1	0.2	0.5	0.4	0.1	0.7	0.1
Hypertension (Self-reported)	0.2	0.5	2.0	-1.3	-0.5	-0.1	-0.3	1.1	-0.5	1.4	-0.3	0.4	-0.2	0.0	-0.6	-1.0	-0.1
Qualifications: nursing, teaching	0.2	0.3	0.8	0.2	0.2	-0.4	-0.9	-0.9	0.7	-0.5	0.0	0.5	0.3	0.9	0.6	0.5	0.2
Mouth/teeth dental problems: Mouth ulcers	0.2	0.3	0.8	0.6	0.9	0.9	0.3	0.3	0.2	0.5	0.5	-0.5	-0.1	0.3	-0.0	0.4	0.9
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.2	0.4	1.4	0.4	-0.5	0.1	0.1	-0.4	0.1	-0.8	-0.2	1.2	1.0	0.9	0.6	0.6	-0.4
Miserableness	0.2	0.3	1.0	0.2	0.1	-1.0	-0.4	-0.9	0.2	-0.5	-0.9	-0.8	-0.6	0.2	0.1	-0.1	-0.7
Tinnitus: Yes, now most or all of the time	0.2	0.2	0.6	-0.3	0.0	-0.4	0.7	0.4	-0.5	-0.2	-0.1	-0.2	0.7	0.4	-0.4	0.7	-0.5
Risk taking	0.2	0.3	1.3	-0.8	-0.9	0.1	-0.2	0.1	-0.8	-1.1	0.0	0.1	-0.7	-0.5	0.2	-0.6	-0.4
Myopia	0.2	0.3	1.5	-0.0	-0.1	-0.8	-1.2	-0.4	-0.7	0.9	0.2	0.9	-0.1	0.3	0.6	-0.2	-0.3
Vascular/heart problems diagnosed by doctor	0.2	0.7	4.1	0.7	-0.5	-0.8	-0.6	-1.5	0.0	-2.0	-0.3	-0.4	-0.6	-0.3	0.4	0.6	-0.8
Medication: Omeprazole (e.g. Zanprol)	0.2	0.2	1.1	-0.2	-0.4	-0.2	-0.2	0.3	-1.1	0.8	-0.5	0.1	-0.4	0.7	0.1	0.5	-0.1
Pain experienced in last month	0.2	0.3	0.9	-0.4	-0.3	0.7	0.8	0.5	0.7	-0.9	0.1	0.9	0.7	0.4	0.0	0.1	-0.5
Depressed Affect (Nagel 2018)	0.1	0.2	1.2	0.3	0.8	-0.0	0.3	0.1	1.1	0.8	0.1	0.4	0.4	-0.1	0.8	0.2	0.2
Waist Hip Ratio (WHR)	0.1	0.5	2.2	-1.5	-0.4	-0.3	0.9	0.9	0.3	0.8	-0.6	-0.8	-0.2	0.6	-1.1	-0.5	-0.3
Systolic Blood Pressure	0.1	0.6	2.1	-1.4	-1.0	-0.2	-0.3	0.9	0.4	0.5	-0.7	-0.2	-0.5	1.2	-0.5	-1.2	-0.4
Cardiovascular Disease	0.1	0.5	1.5	-1.1	-0.3	0.6	0.1	1.2	-0.3	1.1	-0.1	-0.3	0.4	0.6	-1.1	-0.6	0.2
Hypothyroidism (self reported)	0.1	0.2	0.8	-0.0	-0.5	-0.3	0.4	-0.9	-0.7	-0.9	-0.7	-0.0	-0.5	0.1	0.4	0.0	-0.1
Lung FEV1/FVC ratio	0.1	0.6	2.6	0.8	0.3	0.9	0.2	0.5	-0.6	1.0	1.2	1.4	1.6	0.3	0.3	-0.4	0.2
Lung FVC	0.1	0.7	2.2	-0.6	-1.2	-0.4	0.1	0.1	-0.9	-1.5	-1.0	0.6	0.5	1.3	-0.2	0.2	-1.4
Hair Pigment	0.1	3.5	8.1	1.0	2.6	2.1	1.8	1.1	2.3	2.7	2.2	1.5	1.1	0.3	1.9	1.6	2.9
Supplements: Zinc	0.1	0.1	0.2	-0.3	-0.1	0.3	0.2	0.4	-0.3	0.4	0.1	0.4	0.1	0.4	-0.0	-0.1	-0.1
Diabetes (father)	0.1	0.2	1.0	0.1	-0.2	0.2	0.4	-0.4	0.8	-0.2	0.2	0.4	0.4	1.0	0.0	-0.5	-0.1
Current tobacco smoking	0.1	0.1	0.8	-0.4	-0.1	-0.4	-0.3	-0.3	-0.3	-0.1	0.1	0.4	-0.9	0.2	0.6	0.1	-0.0
Medication: Levothyroxine sodium	0.1	0.2	0.9	-0.2	-0.1	-0.2	-0.2	-0.5	-1.0	-0.9	-0.2	-0.2	-0.5	0.0	0.5	-0.3	0.6
Sitting height	0.1	0.9	3.6	0.2	-0.8	-1.0	-1.7	-1.9	1.0	-1.3	-0.6	-0.7	-0.5	0.5	-0.0	-0.5	-1.2
Had other major operations	0.1	0.1	0.9	-0.1	0.1	-0.4	1.0	-0.2	-0.1	-0.4	-0.0	0.0	-0.1	0.4	0.2	0.1	0.3
Frequency of tiredness / lethargy in last 2 weeks	0.1	0.2	0.8	-0.2	0.5	-0.3	-0.7	-0.3	-0.9	-0.0	-0.1	-0.3	-0.6	0.3	0.5	0.6	0.4
Standing height	0.1	1.0	5.2	0.6	-0.3	-0.9	-0.9	-2.3	2.2	-0.6	0.1	-0.3	-0.6	-0.7	0.7	-0.0	-0.5
Comparative body size at age 10	0.1	0.4	1.6	-0.1	-0.8	-0.6	-0.5	-0.5	1.3	-1.0	-0.0	-0.0	0.4	-0.3	-0.8	-0.3	-0.6
Smoking status: Current	0.1	0.1	0.4	-0.4	-0.0	-0.2	-0.3	-0.0	0.2	0.0	0.3	0.5	-0.6	0.1	0.6	-0.0	0.1
Diastolic blood pressure, automated reading	0.1	0.4	1.6	-0.6	-1.3	-1.0	-0.6	-0.2	0.0	-0.6	-0.6	0.1	0.6	0.4	-0.9	-0.5	-0.9
Height	0.0	0.6	5.2	0.5	0.5	-0.5	-0.4	-2.3	0.6	-0.8	0.7	-0.2	-0.1	-0.3	0.9	-0.3	0.5

Hub : Genes

MIS12

Models

Trait associations