Hub : Genes

MLKL

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.1950	0.0650	3.7e-04	0.113	NA	0.047	NA	0.104	1.7e-09	NA	9.8e-05	NA	8.3e-09
2	GTEx	Artery Tibial	0.0732	0.0342	5.8e-03	0.088	NA	0.036	NA	0.081	2.2e-07	NA	7.4e-04	NA	6.4e-07
3	GTEx	Brain Hypothalamus	0.2230	0.1010	8.4e-03	0.046	NA	0.013	NA	0.013	3.1e-02	NA	1.5e-01	NA	1.5e-01
4	GTEx	Breast Mammary Tissue	0.1780	0.0620	1.5e-03	0.096	NA	0.018	NA	0.038	1.3e-05	NA	3.9e-02	NA	5.0e-03
5	GTEx	Breast Mammary Tissue (Male)	0.0520	0.0502	1.9e-01	-0.012	NA	-0.009	NA	-0.004	8.0e-01	NA	5.8e-01	NA	4.2e-01
6	GTEx	Breast Mammary Tissue (Female)	0.1457	0.0811	5.6e-02	0.019	NA	0.004	NA	0.011	8.9e-02	NA	2.4e-01	NA	1.4e-01
7	GTEx	Cells Transformed fibroblasts	0.0760	0.0350	1.8e-03	0.122	NA	0.133	NA	0.155	2.1e-09	NA	3.8e-10	NA	1.1e-11
8	GTEx	Esophagus Muscularis	0.1200	0.0510	1.0e-03	0.103	NA	0.079	NA	0.082	8.7e-07	NA	1.5e-05	NA	1.1e-05
9	GTEx	Nerve Tibial	0.2149	0.0638	2.4e-06	0.132	NA	0.113	NA	0.166	1.4e-09	NA	2.2e-08	NA	7.6e-12
10	METSIM	Adipose	0.0839	0.0288	2.8e-05	0.094	0.029	0.060	0.074	0.077	6.1e-14	2.6e-05	2.4e-09	3.5e-11	1.2e-11
11	NTR	Blood	0.0403	0.0135	8.7e-07	0.009	0.016	0.020	0.018	0.019	5.3e-04	5.1e-06	4.0e-07	1.2e-06	6.1e-07
12	YFS	Blood	0.2634	0.0351	0.0e+00	0.153	0.301	0.317	0.307	0.317	1.2e-47	3.0e-100	1.2e-106	1.2e-102	7.4e-107
13	TCGA	Breast Invasive Carcinoma	0.1404	0.0466	1.0e-10	0.053	0.051	0.060	NA	0.064	5.5e-11	1.2e-10	2.3e-12	NA	4.1e-13
14	TCGA	Colon Adenocarcinoma	0.1400	0.0680	1.3e-03	0.030	0.052	0.051	NA	0.058	6.9e-03	5.9e-04	6.2e-04	NA	2.7e-04
15	TCGA	Glioblastoma Multiforme	0.2200	0.0890	2.8e-04	0.025	0.085	0.100	NA	0.079	5.8e-02	1.5e-03	6.1e-04	NA	2.2e-03
16	TCGA	Head and Neck Squamous Cell Carcinoma	0.0682	0.0368	1.3e-04	0.078	0.026	0.055	NA	0.070	4.7e-09	6.1e-04	8.7e-07	NA	2.5e-08
17	TCGA	Kidney Renal Clear Cell Carcinoma	0.2233	0.0676	1.0e-11	0.104	0.125	0.144	NA	0.149	1.0e-11	6.8e-14	7.0e-16	NA	1.9e-16
18	TCGA	Kidney Renal Papillary Cell Carcinoma	0.0670	0.0330	9.0e-04	0.027	0.045	0.024	NA	0.029	1.0e-02	1.3e-03	1.6e-02	NA	8.1e-03
19	TCGA	Brain Lower Grade Glioma	0.1403	0.0618	3.3e-05	0.066	0.060	0.052	NA	0.058	5.2e-08	2.3e-07	1.4e-06	NA	3.4e-07
20	TCGA	Lung Squamous Cell Carcinoma	0.0592	0.0311	2.9e-03	0.008	0.013	0.006	NA	0.004	3.3e-02	9.9e-03	6.6e-02	NA	1.2e-01
21	TCGA	Prostate Adenocarcinoma	0.1727	0.0663	6.7e-07	0.075	0.053	0.074	NA	0.089	2.9e-08	3.1e-06	3.7e-08	NA	1.3e-09
22	TCGA	Soft Tissue Sarcoma	0.1500	0.0580	2.5e-04	-0.003	0.040	0.046	NA	0.028	5.4e-01	1.9e-03	9.7e-04	NA	8.1e-03
23	TCGA	Skin Cutaneous Melanoma	0.2090	0.0880	1.5e-03	0.012	0.094	0.062	NA	0.063	1.5e-01	1.8e-03	9.4e-03	NA	9.0e-03
24	TCGA	Stomach Adenocarcinoma	0.0580	0.0340	5.9e-03	0.020	0.017	0.013	NA	0.018	1.3e-02	2.1e-02	3.5e-02	NA	1.8e-02
25	TCGA	Thyroid Carcinoma	0.1620	0.0650	7.6e-06	0.070	0.061	0.052	NA	0.068	2.4e-07	1.3e-06	8.3e-06	NA	3.2e-07

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25
Bipolar Disorder (2018)	0.6	1.0	2.2	0.7	0.6	-0.5	0.7	0.5	0.7	1.4	0.7	1.2	0.9	-1.3	-0.6	1.3	0.3	0.9	1.3	1.3	0.6	0.7	1.1	1.2	0.8	1.5	1.1	1.2
Bipolar Disorder or Schizophrenia	2.0	4.8	11.5	1.4	1.3	2.1	1.6	2.1	1.4	2.9	1.9	1.8	1.5	-1.5	-2.3	2.9	1.4	2.7	2.7	2.6	2.6	0.8	1.8	2.5	2.1	3.4	2.8	2.4
Depressed Affect (Nagel 2018)	0.3	0.7	4.8	-0.1	-0.0	-2.2	-0.2	-2.1	-0.0	0.1	0.1	-0.1	-0.0	1.6	0.7	0.1	0.2	-0.5	0.1	-0.1	-0.4	0.6	1.7	-0.0	0.5	0.1	-0.6	0.0
Depression (Nagel 2018)	0.8	1.2	7.6	0.3	0.4	-0.8	0.3	-1.2	0.3	1.3	0.8	0.3	0.2	1.0	-0.9	1.4	1.5	1.1	1.4	1.0	1.4	1.0	2.8	0.8	0.7	1.4	0.6	0.7
Intelligence (Savage-Jansen 2018)	0.2	0.8	1.4	0.8	1.1	0.8	1.1	-0.1	1.0	0.9	0.9	1.1	0.9	-1.0	-0.7	0.9	0.3	0.6	0.6	1.1	0.9	0.7	1.2	1.0	0.6	1.2	0.3	1.0
Neuroticism (Nagel 2018)	0.4	1.0	7.7	-0.4	-0.5	-1.6	-0.5	-1.4	-0.4	1.0	0.2	-0.1	-0.4	1.2	0.0	1.2	1.6	-0.5	1.6	0.4	0.3	0.5	2.8	0.3	1.4	0.2	0.7	0.2
Schizophrenia (2018)	2.1	4.4	10.0	1.3	1.2	3.2	1.5	2.3	1.2	2.6	1.9	1.4	1.2	-0.9	-2.5	2.6	1.5	2.6	2.4	2.4	2.8	0.4	1.2	2.2	2.1	3.2	2.8	2.1
Schizophrenia vs Biploar Disorder	0.4	0.6	2.5	0.2	0.3	1.5	0.4	1.2	0.2	0.4	0.4	-0.0	-0.0	-0.5	-1.6	0.4	1.1	1.3	0.4	0.5	1.5	0.3	-0.1	0.4	-0.3	0.7	0.7	0.2
Worry (Nagel 2018)	1.3	2.7	11.3	-0.1	-0.4	-0.9	-0.4	0.7	-0.2	2.4	0.7	1.0	-0.2	0.1	-1.1	2.7	3.4	0.3	3.1	1.5	1.5	0.5	3.3	1.2	2.1	0.3	2.4	0.8
Alzheimer’s Disease (in mother)	0.5	0.6	3.7	-0.6	-0.7	1.8	-0.7	1.9	-0.7	0.0	-0.2	-0.8	-0.7	-0.9	-0.4	0.1	1.0	0.3	0.5	-0.2	1.2	0.0	0.2	-0.3	0.6	0.8	0.9	-0.2
Alzheimer’s Disease (in father)	1.6	1.8	3.6	-1.8	-1.9	0.0	-1.9	-1.3	-1.8	-1.1	-1.6	-1.8	-1.8	1.2	1.1	-1.1	-0.1	-1.0	-0.3	-1.6	-0.6	-1.7	-0.2	-1.8	-0.4	-1.2	-0.4	-1.8
Alzheimer’s Disease (including proxy)	1.8	2.6	6.9	-2.4	-2.6	1.3	-2.4	1.2	-2.5	-1.2	-2.1	-2.3	-2.4	0.5	1.0	-1.0	0.8	-1.1	0.0	-1.8	0.3	-1.8	-0.1	-2.1	0.5	-0.7	0.4	-2.1
Crohns Disease (2017)	1.2	2.6	5.8	1.1	1.0	0.7	1.2	0.8	1.1	2.4	1.5	1.1	0.9	-1.0	-2.0	2.4	1.7	2.0	2.3	2.1	1.9	0.6	1.4	1.9	1.0	1.8	2.1	1.6
Irritable Bowel Disease (IBD)	1.6	3.7	8.1	1.9	1.8	0.8	2.0	0.5	1.9	2.5	2.1	2.2	1.9	-1.4	-2.0	2.6	0.5	2.8	1.9	2.5	1.6	1.4	1.0	2.5	2.1	2.0	1.7	2.2
Ulcerative Colitis (UC)	1.3	2.4	5.4	1.9	1.8	0.7	2.0	-0.0	1.9	1.6	1.8	2.2	2.0	-1.1	-1.0	1.7	-0.6	2.2	0.7	1.8	0.5	1.7	0.1	2.0	2.3	1.1	0.7	1.9
Major Depression (MDD)	0.2	0.2	0.9	-0.3	-0.3	-1.0	-0.7	-0.8	-0.4	-0.1	-0.1	0.1	-0.4	0.8	0.5	-0.0	0.3	-0.9	0.2	-0.3	-0.2	0.0	0.9	-0.4	-0.6	-0.1	-0.2	-0.2
Reaction Time	1.0	2.0	4.3	1.4	1.5	0.0	1.6	0.8	1.4	1.5	1.8	1.4	1.2	-1.0	-2.1	1.5	0.7	0.9	1.1	1.8	1.6	1.2	2.0	1.7	0.8	1.2	1.2	1.8
Verbal and Numeric Reasoning (VNR)	0.2	0.4	1.8	0.3	0.3	-0.2	0.5	-0.4	0.4	-0.8	-0.3	-0.1	0.4	-0.4	0.4	-0.8	-1.1	0.2	-1.2	-0.4	-0.4	0.7	-1.1	-0.2	-0.0	0.4	-1.3	-0.0
Breast Cancer	0.3	0.7	2.4	0.5	0.4	1.3	0.3	0.4	0.4	-1.0	0.0	-0.5	0.2	-1.6	-0.2	-0.9	-1.3	-0.4	-1.5	-0.4	-0.1	-0.5	-1.1	-0.3	-0.4	-0.5	-1.6	-0.3
Ovarian Cancer	3.0	4.0	8.7	-1.7	-1.7	1.2	-1.7	-0.7	-1.8	-2.7	-2.1	-1.9	-1.8	0.4	1.5	-2.7	-2.2	-2.1	-2.3	-2.6	-1.7	-2.2	-1.8	-2.6	-1.1	-2.9	-1.8	-2.4
Prostate Cancer	1.7	2.5	6.5	-2.3	-2.5	-0.2	-2.3	0.3	-2.4	-0.3	-1.6	-2.2	-2.3	1.7	0.8	-0.3	1.3	-1.9	1.0	-1.2	-0.3	-2.2	0.9	-1.6	-0.5	-1.3	1.2	-1.7
Age at First Birth	0.2	0.2	1.3	0.3	0.3	0.9	0.2	-0.1	0.3	0.3	0.4	0.5	0.1	-0.8	-1.2	0.2	0.3	0.1	0.2	0.4	0.3	0.1	0.5	0.3	-1.2	-0.3	0.4	0.2
Bipolar Disorder (2011)	0.8	0.8	5.2	1.3	0.0	1.1	0.0	-0.1	1.4	2.3	1.8	2.0	0.0	-1.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Body Mass Index (BMI) (2010)	0.4	0.5	4.8	-0.1	-0.3	-2.2	-0.3	-0.5	-0.2	-0.4	-0.4	0.3	-0.1	1.0	1.0	-0.4	-1.0	-0.5	-0.5	-0.4	-1.1	-0.3	0.3	-0.2	0.4	-0.6	-1.1	-0.1
Coronary Artery Disease (CAD)	0.4	0.5	4.3	0.2	0.3	-1.0	0.4	-2.1	0.2	-1.4	-0.3	0.4	0.1	1.2	1.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Crohns Disease (2012)	1.0	1.7	3.2	1.2	1.1	0.4	1.3	0.8	1.2	1.7	1.3	1.4	1.2	-1.1	-1.3	1.8	1.2	0.6	1.4	1.7	1.2	0.9	1.2	1.6	1.6	1.2	1.6	1.6
Mean Putamen Volume	0.8	0.9	3.5	-0.2	-0.2	0.5	-0.0	-1.2	-0.2	-1.2	-0.8	-1.1	-0.1	-0.1	1.1	-1.3	-1.7	-0.4	-1.5	-1.0	-1.4	-0.5	-1.9	-0.7	-0.8	-0.7	-1.3	-0.6
Fasting Glucose	1.4	1.7	4.2	-1.2	-1.4	-1.4	-1.1	-0.9	-1.3	-1.4	-1.7	-0.8	-1.0	2.0	1.9	-1.4	-1.2	-1.4	-1.0	-1.3	-1.6	-1.5	-1.2	-1.4	-0.0	-0.6	-1.1	-1.3
HbA1C	0.0	0.1	0.3	0.1	0.3	0.1	0.5	-0.1	0.2	0.1	0.2	0.2	0.1	-0.0	-0.1	0.0	-0.3	0.4	0.0	0.1	0.5	-0.0	0.1	0.1	0.0	0.6	0.0	0.1
HDL Cholesterol	1.1	1.8	6.6	-0.8	-0.5	-0.3	-0.6	-1.9	-0.6	-1.4	-1.0	-0.6	-0.9	1.4	0.9	-1.6	-1.1	-2.6	-1.3	-1.3	-2.1	-0.9	-0.4	-1.3	-2.6	-1.8	-1.0	-1.1
LDL Cholesterol	0.4	0.6	2.8	0.0	-0.2	-1.4	-0.0	-1.2	-0.0	-0.4	-0.4	-0.0	0.2	1.6	1.7	-0.3	-0.5	-1.3	-0.6	-0.4	-1.3	0.1	0.3	-0.3	1.1	-0.9	-0.6	-0.2
Lupus	0.3	0.5	2.1	-0.6	-0.6	-1.1	-0.7	-0.4	-0.5	-0.3	-0.6	-1.2	-0.6	-0.8	0.1	-0.3	0.6	-0.6	-0.1	-0.4	-0.5	-0.4	1.3	-0.4	-0.9	-1.4	-0.4	-0.5
Neuroticism (2016)	0.6	0.9	3.6	-1.5	-1.2	-1.1	-1.4	-1.9	-1.4	-0.4	-0.9	-0.8	-1.3	0.9	1.1	-0.3	0.7	0.0	0.4	-1.0	-0.7	-0.4	0.2	-0.9	-0.6	-0.2	-0.1	-1.1
Primary Biliary Cirrhosis	0.1	0.1	0.5	-0.0	-0.0	0.1	0.3	-0.3	0.0	0.1	-0.0	0.1	-0.1	0.5	-0.2	0.2	0.2	-0.7	0.2	0.2	0.1	-0.6	0.2	-0.0	-0.6	0.5	-0.0	-0.0
Rheumatoid Arthritis	0.1	0.2	0.6	-0.3	-0.2	0.5	-0.3	0.3	-0.2	0.1	0.1	0.2	-0.3	-0.8	-0.4	0.2	0.4	0.8	0.2	0.1	0.7	0.1	0.8	0.0	0.5	0.4	0.2	-0.1
Schizophrenia (2014)	1.7	3.8	8.8	1.2	1.1	2.6	1.6	1.6	1.2	2.6	1.7	1.7	1.2	-0.4	-2.0	2.7	1.3	2.3	2.5	2.3	2.3	0.5	1.2	2.1	2.2	3.0	2.6	2.0
Triglycerides	1.1	1.8	4.6	0.9	0.8	1.0	0.7	2.1	0.9	1.5	1.0	1.2	1.0	-1.5	-1.3	1.5	1.2	1.9	1.3	1.5	1.9	0.9	0.4	1.3	1.9	1.5	1.4	1.2
Type 2 Diabetes (T2D) (2012)	0.6	0.7	2.0	-1.1	-1.3	-0.4	-1.3	0.3	-1.2	-0.6	-1.4	-1.0	-1.0	0.7	1.0	-0.6	-0.2	-0.4	-0.0	-0.9	-0.9	-0.5	-0.5	-0.9	0.3	-0.5	0.2	-1.0
Ulcerative Colitis	0.6	0.9	2.5	1.0	0.9	-0.5	1.1	-1.6	1.0	1.0	1.1	0.9	1.1	-0.4	-0.6	1.0	-0.7	0.9	0.5	1.1	-0.3	1.2	1.0	1.3	1.0	0.6	0.1	1.3
Blood Eosinophil Count	0.1	0.6	2.2	-0.4	-0.7	-1.5	-0.5	-1.4	-0.6	-0.6	-0.8	-0.8	-0.7	0.5	0.5	-0.6	0.6	-0.8	-0.3	-0.7	-0.7	-0.5	0.5	-0.6	-1.2	-1.4	-0.7	-0.8
Blood Platelet Count	0.2	1.8	7.8	1.5	1.5	-2.4	1.4	-2.8	1.5	0.7	1.4	1.6	1.5	0.4	-0.2	0.6	0.5	-0.3	-0.1	0.8	-1.1	1.9	1.9	1.2	-1.1	-0.4	-0.4	1.4
Blood Red Count	0.4	3.7	26.4	-0.7	-0.8	-2.9	-0.5	-5.1	-0.7	-1.3	-1.1	-1.8	-0.5	2.1	2.6	-1.4	-1.6	-2.8	-1.3	-1.4	-3.6	0.0	0.3	-1.0	-1.5	-1.7	-1.5	-0.9
Blood White Count	0.2	1.8	6.8	-0.9	-0.9	2.6	-1.2	1.1	-0.9	1.3	0.0	-1.0	-1.1	-2.0	-1.2	1.3	1.9	0.3	2.3	0.6	0.4	-0.1	1.5	0.4	-1.8	-0.6	2.6	0.1
Heel T-Score	0.3	2.1	3.9	-1.2	-1.1	-1.6	-1.2	-1.4	-1.1	-1.6	-1.6	-0.9	-1.1	1.9	1.3	-1.6	-1.3	-1.5	-1.3	-1.6	-1.6	-1.9	-2.0	-1.6	-1.3	-1.4	-1.2	-1.5
BMI	0.3	2.0	12.0	-0.8	-0.8	-2.9	-0.9	-3.5	-0.9	-0.8	-0.8	-2.4	-0.8	1.6	1.8	-0.7	-0.0	-1.3	-0.4	-1.1	-1.6	0.7	1.7	-0.8	-0.4	-0.5	-1.1	-0.7
Height	0.0	0.6	2.4	-0.8	-0.7	-0.2	-1.0	1.5	-0.7	-0.5	-0.4	0.4	-0.6	-0.8	0.2	-0.4	-0.3	-0.9	-0.3	-0.5	1.0	-1.1	-0.8	-0.8	1.1	0.5	0.5	-0.7
Waist Hip Ratio (WHR)	0.2	0.8	4.0	0.8	0.9	-1.3	1.2	-1.9	0.9	-0.2	0.4	0.3	0.7	0.6	0.2	-0.2	-0.5	-0.9	-0.9	0.0	-1.6	0.2	-0.0	0.3	-0.9	-2.0	-1.1	0.4
Systolic Blood Pressure	0.1	0.5	2.1	-0.3	-0.5	-0.9	-0.8	-1.1	-0.4	-0.6	-0.5	-0.8	-0.2	0.5	0.8	-0.6	-0.3	-0.8	-0.6	-0.6	-1.2	-0.4	-0.2	-0.6	0.5	-1.5	-0.2	-0.6
Smoking Status	0.3	0.7	2.5	0.8	0.5	-1.4	0.5	-0.2	0.7	-0.4	0.1	0.2	0.9	0.7	1.1	-0.5	-1.1	-1.3	-1.1	-0.1	-1.6	0.5	-0.7	0.4	-0.8	-0.4	-1.4	0.6
Allergy or Eczema	0.1	0.3	2.6	-0.2	-0.1	1.1	-0.1	1.1	-0.2	0.2	0.1	0.1	-0.2	-1.6	-0.3	0.2	0.6	0.8	0.4	0.1	0.7	0.6	0.3	0.1	0.1	0.4	0.6	-0.0
Cardiovascular Disease	0.5	1.7	4.8	2.2	1.9	-0.4	1.7	-0.9	2.0	0.6	1.9	1.2	2.0	-1.1	-0.8	0.7	-0.4	-0.3	-0.6	1.2	-0.1	1.7	1.6	1.4	1.5	-0.6	-0.7	1.7
Hypothyroidism (self reported)	0.9	2.1	5.1	0.8	0.5	-0.9	0.8	1.1	0.6	2.1	0.9	1.1	0.6	-0.5	-1.2	2.1	1.9	2.1	2.2	1.8	1.5	1.3	1.2	1.6	0.7	2.2	1.8	1.3
Respiratory disease	0.7	1.6	7.7	-0.2	-0.4	0.9	-0.4	1.6	-0.3	1.7	0.2	0.2	-0.2	-0.6	-0.8	1.9	2.8	0.4	2.3	1.1	1.7	-0.1	2.4	0.8	1.1	0.7	1.8	0.5
Type 2 Diabetes (T2D) (2018)	0.2	0.4	2.2	-0.7	-0.6	-1.5	-0.2	-0.0	-0.7	0.1	-0.3	-1.1	-0.7	0.4	0.2	0.2	1.2	0.7	0.6	-0.4	0.6	0.1	1.2	-0.3	0.7	0.1	0.3	-0.2
Lung FEV1/FVC ratio	0.3	1.8	6.8	0.2	0.3	-1.8	0.6	-2.6	0.3	-1.5	-0.3	-0.7	0.3	0.0	0.8	-1.6	-1.5	-2.4	-2.0	-1.0	-2.2	0.3	-0.8	-0.7	-1.5	-1.6	-1.8	-0.4
Lung FVC	0.3	1.4	5.8	1.5	1.2	2.4	1.4	1.1	1.4	-0.1	0.8	1.2	1.6	-2.2	-0.3	-0.3	-1.5	0.3	-1.1	0.4	-0.7	0.8	-2.1	0.7	0.2	-0.3	-0.5	0.9
Neuroticism	0.6	1.4	8.1	-0.8	-0.9	-2.2	-0.9	-2.0	-0.8	0.8	-0.2	-0.4	-0.7	1.7	0.9	1.1	1.8	-0.5	1.6	-0.0	-0.2	0.5	2.8	-0.0	1.5	-0.3	0.4	-0.1
Chronotype (morning person)	1.3	3.1	6.7	-1.3	-1.4	-2.1	-1.1	-0.3	-1.4	-2.6	-1.9	-2.0	-1.3	1.0	1.9	-2.5	-1.4	-1.2	-2.4	-2.3	-1.4	-1.1	-1.6	-2.1	-0.5	-2.3	-2.4	-1.9
Hair Pigment	0.0	0.6	3.2	-0.9	-1.1	1.3	-0.7	1.6	-0.9	0.0	-0.6	-0.4	-0.9	0.2	0.4	0.0	0.4	1.2	0.5	-0.3	0.3	-0.6	-1.8	-0.4	0.1	-0.1	0.6	-0.6
Tanning	0.3	3.4	9.3	3.0	3.0	1.5	2.7	0.3	3.0	0.7	2.5	2.6	2.8	-2.2	-1.2	0.6	-1.5	0.7	-1.0	1.6	0.4	1.3	-0.4	1.9	1.1	0.7	-1.2	2.1
Hand grip strength (left)	0.2	0.5	2.8	0.3	0.1	1.4	0.4	0.8	0.2	0.7	0.5	1.0	0.5	-1.3	-0.4	0.7	0.5	0.1	0.7	0.5	0.9	0.3	-0.0	0.7	0.5	1.7	0.6	0.7
Number of treatments/medications taken	1.4	2.5	5.0	2.0	1.8	-0.7	1.6	-0.1	1.9	1.7	1.9	2.2	2.1	-1.0	-0.9	1.7	0.7	2.1	0.8	1.8	1.1	1.9	0.8	2.0	1.7	1.4	0.6	1.9
Average weekly spirits intake	0.4	0.5	2.3	0.8	0.7	1.1	0.8	0.5	0.7	0.1	1.0	0.4	0.7	-1.4	-0.9	0.2	-0.3	0.4	-0.4	0.4	0.4	1.5	0.5	0.5	0.7	-0.6	0.0	0.5
Sensitivity / hurt feelings	0.9	1.6	3.6	-1.7	-1.4	-0.4	-1.7	-0.9	-1.6	-0.7	-1.4	-1.9	-1.7	1.5	1.5	-0.7	0.6	-1.4	0.2	-1.3	-1.1	-1.2	-0.5	-1.3	-1.4	-1.0	-0.6	-1.3
Frequency of depressed mood in last 2 weeks	0.9	1.2	8.3	-0.5	-0.2	-0.8	-0.6	-1.3	-0.4	1.4	0.3	-0.2	-0.6	1.2	-0.5	1.5	1.9	0.6	2.2	0.6	0.8	0.5	2.9	0.5	-0.2	0.9	1.4	0.4
Hearing difficulty/problems: Yes	3.6	5.5	9.8	3.0	2.9	0.1	2.8	0.6	2.9	2.6	3.0	2.2	2.9	-2.3	-2.4	2.5	1.8	0.8	1.4	3.0	1.7	3.0	2.1	3.1	1.1	2.1	1.1	3.1
Relative age of first facial hair	0.1	0.1	0.7	-0.2	-0.1	0.5	-0.2	0.4	-0.1	-0.2	-0.2	-0.3	-0.2	0.5	-0.1	-0.2	-0.1	-0.8	-0.2	-0.1	-0.3	-0.5	-0.1	-0.3	-0.3	-0.8	-0.1	-0.2
Other serious medical condition/disability diagnosed by doctor	2.4	3.2	9.0	1.6	1.4	0.9	1.5	1.3	1.5	2.1	1.8	1.8	1.6	-0.7	-1.9	2.2	1.1	3.0	1.6	2.1	2.1	1.9	0.7	2.0	2.3	1.9	1.8	1.8
Ever used hormone-replacement therapy (HRT)	0.2	0.2	1.9	0.5	0.4	-1.4	0.4	-0.0	0.5	-0.1	0.4	0.0	0.5	0.6	0.4	-0.1	-0.5	-0.2	-0.4	0.0	-0.7	-0.2	-0.6	0.2	-0.4	-0.6	-0.4	0.2
Ever had hysterectomy (womb removed)	0.5	0.6	3.0	-0.4	-0.1	-1.7	0.0	-1.1	-0.2	-0.6	-0.6	-0.2	-0.2	1.7	1.0	-0.7	-0.9	0.5	-0.6	-0.6	-0.7	0.1	-0.8	-0.5	-0.6	-0.0	-0.6	-0.5
Systolic blood pressure, automated reading	0.2	0.4	2.7	0.2	-0.1	-0.3	0.2	-1.1	0.1	-0.8	-0.1	-0.4	0.2	-0.4	0.4	-0.7	-0.5	-0.8	-1.2	-0.5	-1.2	0.3	-0.2	-0.4	0.3	-1.7	-0.9	-0.3
Eye problems/disorders: Diabetes related eye disease	1.2	1.3	4.9	-1.6	-1.7	1.1	-1.7	1.5	-1.6	0.2	-0.9	-0.8	-1.7	-0.8	-0.4	0.3	2.2	0.4	1.3	-0.4	0.9	-0.6	0.7	-0.6	-0.6	-0.4	1.5	-0.9
Angina	2.8	3.7	10.3	2.9	2.1	-0.1	2.8	-0.2	2.5	1.5	2.3	2.2	2.9	-1.7	-0.9	1.6	0.2	2.1	0.1	1.9	0.6	3.0	-0.2	2.2	3.2	0.5	-0.1	2.3
Medication for hormone replacement therapy	0.5	0.6	2.3	-0.9	-0.9	-0.2	-1.1	1.5	-1.0	-0.2	-0.8	-1.0	-0.9	1.1	-0.0	-0.3	-0.2	-0.4	0.4	-0.4	0.0	-1.5	-0.2	-0.7	-0.8	0.0	0.8	-0.7
Vitamin and mineral supplements	0.4	0.5	2.3	0.1	0.1	-1.5	0.1	-1.0	0.1	-0.7	-0.2	-0.3	0.1	0.5	0.3	-0.8	-0.4	-1.2	-1.0	-0.4	-0.9	0.5	1.0	-0.3	-0.9	-0.9	-0.9	-0.2
Supplements: Zinc	0.3	0.3	1.5	-0.3	-0.2	-0.7	-0.2	0.4	-0.2	0.6	0.0	-0.7	-0.2	-0.1	0.2	0.7	0.3	0.2	1.0	0.2	0.6	-0.7	-0.1	0.2	1.0	1.2	1.1	0.2
Medication: Co-codamol	0.7	0.8	3.3	0.5	0.7	-0.5	0.3	0.9	0.6	1.2	1.1	0.1	0.5	0.6	-0.4	1.2	1.5	0.7	1.2	0.9	1.3	0.7	0.4	1.0	0.0	1.8	1.1	1.0
Medication: Metformin	0.5	0.7	2.4	0.9	0.8	-1.4	1.2	-1.2	0.9	0.2	0.8	0.7	0.9	0.7	-0.4	0.3	0.3	1.5	-0.3	0.4	0.6	1.2	0.9	0.5	0.8	0.2	-0.7	0.6
Diabetes (father)	1.2	1.5	4.1	-0.6	-0.7	0.1	-0.8	0.0	-0.7	-1.5	-1.1	0.1	-0.8	0.4	1.0	-1.7	-1.8	-1.5	-1.4	-1.3	-1.7	-1.2	-1.9	-1.2	-2.0	-1.1	-1.0	-1.0
Diabetes (mother)	0.7	0.9	6.2	-0.1	0.1	-2.5	0.2	-1.3	0.0	-0.6	-0.3	0.4	0.0	1.7	1.4	-0.7	-0.2	-0.6	-0.7	-0.6	-1.2	0.4	-1.1	-0.2	-2.1	0.4	-0.9	-0.2
Severe depression (siblings)	0.6	0.7	5.3	0.1	0.0	2.3	0.0	1.5	0.1	0.5	0.5	-0.6	0.0	-0.8	-1.0	0.6	0.2	1.1	0.6	0.4	1.2	0.5	0.4	0.4	1.0	0.4	0.8	0.4
Pack years adult smoking proportion	0.2	0.4	1.7	0.3	0.1	-0.9	0.4	-1.2	0.3	0.5	0.1	1.0	0.4	0.7	0.5	0.6	0.3	0.3	0.3	0.3	-0.5	0.9	0.4	0.5	1.3	-0.3	-0.3	0.6
Impedance of leg (right)	0.1	0.6	4.4	0.2	0.4	-1.0	0.1	-1.5	0.2	-0.6	0.1	0.0	0.1	0.4	0.3	-0.6	-0.5	-1.0	-0.9	-0.5	-1.6	0.4	0.1	-0.3	-0.4	-2.1	-0.6	-0.2
Leg fat-free mass (left)	0.3	1.6	4.3	-1.9	-1.9	-1.2	-1.9	-0.4	-1.8	-0.8	-1.5	-2.1	-1.6	1.2	1.9	-0.7	-0.1	-1.4	0.1	-1.4	-0.2	-1.1	0.0	-1.4	0.4	0.4	-0.2	-1.4
Trunk fat percentage	1.3	5.1	13.7	-1.2	-0.9	-3.3	-1.1	-3.7	-1.0	-2.6	-1.6	-2.4	-0.9	2.9	3.4	-2.4	-1.9	-2.5	-2.6	-2.6	-3.5	-0.1	-1.1	-2.0	-0.7	-2.5	-2.5	-1.7
Hand grip strength (right)	0.4	1.0	2.7	-1.5	-1.7	1.3	-1.3	1.5	-1.5	-0.1	-1.0	-0.2	-1.3	-0.7	0.4	-0.1	0.9	-0.4	0.8	-0.7	0.8	-0.8	-0.7	-0.8	-0.5	1.5	1.0	-0.8
Townsend deprivation index at recruitment	0.7	1.0	2.1	0.5	0.8	0.6	0.3	0.8	0.5	1.4	1.0	0.5	0.4	0.2	-1.3	1.4	1.4	1.3	1.4	1.2	1.5	0.4	0.8	1.0	0.4	1.3	1.3	0.8
Current tobacco smoking	0.2	0.3	1.3	-0.3	-0.5	-0.7	-0.6	-0.6	-0.4	0.4	-0.1	-0.4	-0.2	0.6	0.6	0.4	-0.1	-1.0	0.8	-0.0	-0.3	-0.1	1.2	0.2	0.3	0.5	0.4	0.2
Average weekly fortified wine intake	0.8	0.9	5.7	0.8	0.4	2.4	0.6	0.9	0.6	0.3	0.7	0.4	0.5	-1.9	-1.6	0.4	-1.1	1.3	-0.0	0.9	1.2	0.1	1.2	0.5	0.8	0.5	-0.1	0.6
Maternal smoking around birth	0.8	1.2	2.9	1.4	1.4	-0.9	1.7	-0.5	1.4	1.4	1.6	1.1	1.4	-0.1	-0.5	1.2	0.8	0.5	0.8	1.3	0.0	1.3	0.5	1.5	-0.6	0.7	0.4	1.4
Fed-up feelings	1.8	3.2	10.7	-1.4	-1.3	-2.3	-1.3	-3.3	-1.3	-2.0	-1.3	-1.2	-1.2	3.1	2.5	-1.8	-1.1	-1.9	-1.7	-2.2	-1.7	-0.3	0.6	-1.9	0.4	-1.7	-2.4	-1.6
Frequency of unenthusiasm / disinterest in last 2 weeks	0.6	0.7	6.0	-0.3	-0.3	-0.4	-0.4	-2.3	-0.3	-0.5	-0.1	-0.2	-0.3	2.5	0.9	-0.3	-0.4	-0.3	-0.4	-0.6	-0.2	-0.2	0.9	-0.7	1.0	-0.4	-1.3	-0.5
Relative age voice broke	0.2	0.4	1.1	-0.8	-0.5	0.2	-0.9	1.1	-0.6	-0.5	-0.8	-0.6	-0.7	-0.7	-0.0	-0.6	-0.0	-0.8	-0.2	-0.5	0.1	-0.8	-0.8	-0.6	-0.6	-0.4	0.0	-0.5
Taking other prescription medications	1.4	2.2	3.8	1.9	1.7	-0.6	1.9	-0.5	1.8	1.7	1.8	1.8	2.0	-0.1	-1.0	1.7	0.5	1.2	1.0	1.9	0.8	1.6	1.7	1.9	1.1	1.5	0.6	1.9
Age when periods started (menarche)	0.2	0.4	2.7	0.1	-0.2	-1.3	0.4	-1.6	-0.0	-0.4	-0.0	0.3	0.0	0.6	0.3	-0.4	-0.3	-0.3	-0.6	-0.3	-0.7	0.2	-0.3	-0.2	-1.1	-0.3	-1.2	-0.1
Bilateral oophorectomy (both ovaries removed)	2.2	2.6	6.2	-1.2	-1.2	-2.4	-1.1	-0.9	-1.2	-1.8	-1.7	-1.6	-1.1	1.6	2.3	-1.9	-1.5	-0.9	-1.6	-2.0	-2.2	-0.9	-2.5	-1.7	-1.2	-1.3	-1.4	-1.4
Heel bone mineral density (BMD) T-score, automated (left)	1.0	2.2	5.9	-1.4	-1.6	-2.4	-1.9	-1.9	-1.6	-1.2	-1.6	-1.9	-1.6	1.5	1.4	-1.2	-0.4	-1.8	-0.5	-1.6	-1.7	-1.3	0.5	-1.6	-1.0	-1.6	-0.6	-1.5
Tinnitus: Yes, but not now, but have in the past	2.5	2.6	7.3	1.2	0.9	2.7	1.1	2.3	1.0	1.8	1.6	1.0	0.9	-2.1	-2.2	2.1	1.4	1.8	1.6	1.8	2.1	0.4	1.5	1.6	1.6	0.6	1.5	1.5
Qualifications: CSEs or equivalent	1.7	2.3	5.8	-1.0	-1.2	0.4	-0.9	-1.9	-1.1	-1.8	-1.4	-1.2	-1.0	1.6	1.8	-1.6	-2.4	-1.8	-1.7	-1.7	-1.9	-1.8	0.1	-1.5	0.0	-1.8	-2.0	-1.4
Serious illness, injury or assault to yourself	2.3	2.8	7.3	-2.3	-2.2	0.7	-2.5	1.4	-2.3	0.8	-1.2	-2.0	-2.3	0.4	-0.6	0.9	2.6	0.2	2.5	-0.3	1.7	-1.8	2.0	-0.7	0.0	0.6	2.7	-1.2
High blood pressure	0.4	1.1	2.8	1.7	1.3	-1.2	1.3	-0.3	1.5	-0.2	1.0	1.1	1.5	-1.1	0.1	-0.1	-0.2	-1.0	-1.3	0.5	-0.7	1.1	0.3	0.8	0.7	-1.4	-1.3	1.0
Hayfever, allergic rhinitis or eczema	0.3	0.7	2.1	-1.3	-1.1	0.8	-1.3	-0.2	-1.2	-0.7	-1.0	-1.4	-1.2	-0.7	0.8	-0.7	0.1	0.3	-0.0	-1.0	-0.3	0.0	-0.8	-0.9	-0.8	0.3	0.1	-1.0
Multivitamins +/- minerals	0.7	0.9	4.6	-0.2	-0.4	1.9	-0.1	1.7	-0.3	0.8	0.1	0.3	-0.1	0.1	-0.1	1.0	-0.1	1.6	1.2	0.5	1.2	-0.8	-0.9	0.3	2.1	1.3	1.1	0.2
Stomach or abdominal pain in last month	0.8	1.1	3.5	-1.3	-1.2	-0.7	-1.4	0.6	-1.3	0.5	-0.7	-1.7	-1.5	0.4	-0.2	0.6	1.9	-0.4	1.6	-0.2	0.4	-0.6	1.5	-0.3	-1.0	-0.5	1.3	-0.5
Supplements: Glucosamine	1.5	1.9	6.2	-1.9	-1.8	1.7	-1.8	2.5	-1.9	-0.6	-1.5	-1.2	-1.8	1.0	0.6	-0.4	0.9	0.3	0.5	-1.0	1.4	-1.7	-1.7	-1.4	0.9	0.3	0.7	-1.7
Diverticular disease/diverticulitis (self-reported)	0.2	0.3	1.9	-0.1	0.1	-0.2	-0.1	-0.3	-0.1	-0.6	0.0	-0.8	-0.3	0.7	-0.3	-0.5	-0.4	-0.7	-0.6	-0.5	-0.1	0.3	1.4	-0.4	-0.5	-0.7	-0.3	-0.3
Medication: Atenolol	0.4	0.5	3.2	-0.0	-0.4	-1.8	-0.1	-1.6	-0.2	-0.7	-0.3	-0.6	-0.1	0.5	0.7	-0.6	-1.1	-0.4	-0.8	-0.6	-0.7	-0.2	0.6	-0.5	0.3	-0.7	-1.0	-0.3
Medication: Levothyroxine sodium	0.9	1.6	3.6	1.3	1.2	-1.1	1.4	-0.5	1.3	1.5	1.1	1.4	1.2	-0.5	-0.8	1.5	0.4	1.2	1.1	1.6	0.6	1.7	1.8	1.7	0.6	1.9	0.4	1.5
Sitting height	0.3	1.9	10.4	1.0	1.0	1.9	1.0	3.2	1.1	1.3	1.1	0.9	1.1	-2.3	-0.9	1.3	0.4	0.2	1.0	1.4	1.5	-0.0	-0.3	1.3	1.7	1.6	1.3	1.3
Chronic bronchitis/emphysema (father)	0.3	0.3	1.1	-0.1	-0.0	0.6	-0.3	-0.1	0.0	0.5	0.6	-0.3	-0.1	-0.8	-0.9	0.6	1.1	-0.1	0.7	0.6	0.7	0.6	0.9	0.4	-0.3	0.4	0.7	0.2
High blood pressure (mother)	0.1	0.2	1.2	0.6	0.2	-0.0	0.2	-0.2	0.4	0.1	0.1	0.5	0.4	-0.8	-0.0	0.2	0.2	-1.1	-0.2	0.1	-0.4	0.2	0.7	0.3	0.2	-0.8	-0.5	0.5
Body mass index (BMI)	0.7	2.9	12.2	-0.5	-0.6	-2.7	-0.5	-3.5	-0.5	-1.7	-1.0	-1.8	-0.3	2.1	2.6	-1.6	-1.4	-2.1	-1.9	-1.7	-2.8	0.6	-0.1	-1.1	-0.5	-1.5	-2.2	-0.9
Impedance of leg (left)	0.1	0.6	4.8	0.2	0.4	-0.9	0.2	-1.2	0.2	-0.8	-0.0	0.3	0.1	0.7	0.2	-0.8	-0.5	-0.7	-1.1	-0.6	-1.4	0.0	0.0	-0.5	-0.5	-2.2	-0.7	-0.3
Leg predicted mass (left)	0.3	1.7	4.5	-2.0	-1.9	-1.2	-2.0	-0.5	-1.9	-0.9	-1.5	-2.1	-1.7	1.2	1.9	-0.7	-0.1	-1.4	0.1	-1.4	-0.3	-1.1	0.0	-1.4	0.4	0.3	-0.2	-1.4
Trunk fat mass	0.9	4.0	10.8	-1.3	-1.1	-3.1	-1.2	-3.3	-1.1	-2.2	-1.5	-2.4	-1.0	2.5	3.2	-2.1	-1.6	-2.2	-2.1	-2.3	-2.9	-0.0	-0.8	-1.8	-0.3	-1.9	-2.1	-1.6
Waist circumference	0.9	3.4	10.8	-1.1	-1.0	-2.5	-0.9	-3.3	-1.0	-1.9	-1.5	-2.4	-1.0	2.3	2.6	-1.8	-1.2	-2.4	-1.8	-2.0	-2.8	-0.3	-0.3	-1.6	-0.8	-2.2	-1.9	-1.4
Number of incorrect matches in round	0.7	1.1	2.7	0.6	0.6	1.6	0.6	1.2	0.6	1.1	0.7	0.7	0.5	-1.0	-1.6	1.1	0.9	1.6	1.0	1.2	1.5	0.8	0.6	1.1	0.7	1.1	1.3	0.9
Past tobacco smoking	0.1	0.3	2.3	-0.7	-0.5	0.2	-0.5	-0.1	-0.6	0.1	-0.2	-0.2	-0.5	-0.4	0.0	0.2	0.1	0.4	0.6	-0.1	0.8	-0.5	0.3	-0.3	1.5	0.6	0.7	-0.4
Alcohol usually taken with meals	0.6	1.0	2.2	-1.5	-1.5	0.8	-1.4	1.4	-1.4	-0.7	-1.4	0.1	-1.4	-0.5	0.2	-0.8	-0.5	1.2	-0.0	-0.9	0.1	-1.0	-1.1	-1.1	-0.6	-0.5	0.1	-1.2
Nervous feelings	0.9	1.6	4.1	-1.8	-2.0	-0.9	-1.7	-0.9	-1.9	-0.3	-1.3	-1.0	-1.9	1.4	0.7	-0.1	1.1	-1.4	0.8	-0.9	-0.3	-1.6	1.5	-1.4	0.2	-1.8	0.1	-1.5
Frequency of tenseness / restlessness in last 2 weeks	1.2	1.8	9.3	0.5	0.7	0.2	0.4	-0.6	0.6	1.9	1.2	0.7	0.4	0.5	-1.1	2.1	2.1	0.5	2.1	1.4	1.7	0.3	3.0	1.1	2.1	0.7	1.0	1.1
Hearing difficulty/problems with background noise	0.8	1.2	4.5	1.6	1.6	-1.3	1.7	0.3	1.6	0.5	1.2	2.1	1.7	0.6	-0.6	0.4	0.4	1.0	-0.5	0.9	0.3	1.7	-0.4	1.2	0.5	0.8	-0.1	1.1
Hair/balding pattern: Pattern 2	0.7	0.9	5.5	-1.0	-0.9	0.4	-1.2	0.4	-1.0	-0.9	-1.1	-0.2	-1.2	0.8	0.3	-0.9	-0.6	-1.1	-0.4	-1.0	-1.2	-0.7	-0.4	-1.0	-0.8	-2.3	-0.2	-1.0
Had menopause	0.3	0.4	1.8	0.8	0.3	0.7	0.9	0.8	0.6	-0.2	0.1	0.6	0.8	-0.3	0.1	-0.2	0.1	1.1	-0.8	0.2	0.2	0.6	-1.3	0.2	0.8	-0.2	-1.1	0.2
Had other major operations	0.1	0.2	1.2	-0.2	-0.0	-1.0	-0.3	-1.1	-0.1	0.2	0.1	0.1	-0.1	0.0	0.3	0.1	0.2	-0.3	0.4	-0.0	-0.3	0.2	0.5	0.1	-0.7	0.4	0.4	0.1
Forced vital capacity (FVC)	0.2	0.9	4.3	-0.9	-0.6	2.0	-1.1	2.1	-0.8	0.0	-0.3	-0.0	-0.8	-1.9	-0.4	-0.1	0.2	-0.4	0.6	-0.3	0.7	-1.1	-1.1	-0.4	-0.9	0.5	1.1	-0.5
Heel bone mineral density (BMD) T-score, automated (right)	1.3	3.0	7.3	-1.8	-2.0	-2.7	-2.4	-2.1	-2.0	-1.5	-1.8	-1.9	-2.0	1.5	1.5	-1.5	-0.4	-2.1	-0.7	-2.0	-1.7	-1.7	0.1	-2.0	-1.4	-1.5	-0.6	-1.9
Ever unenthusiastic/disinterested for a whole week	1.0	1.2	2.7	-1.2	-1.4	-0.1	-1.4	-0.9	-1.4	-0.5	-1.2	-1.2	-1.4	0.6	0.9	-0.4	1.0	-1.7	0.2	-1.1	-1.3	-1.1	-0.2	-1.1	-1.3	-1.5	-0.2	-1.2
Qualifications: None of the above	1.6	3.4	6.1	2.3	2.2	0.5	2.3	1.7	2.3	2.0	2.5	2.1	2.3	-1.2	-2.1	2.0	0.9	1.0	0.9	2.5	1.4	1.8	1.2	2.4	1.8	0.6	1.1	2.3
Financial difficulties in last 2 years	0.6	0.8	8.7	-0.8	-0.6	2.9	-0.8	-0.5	-0.7	0.5	-0.1	-1.5	-0.6	-0.8	-0.0	0.6	0.7	-0.2	1.0	0.1	0.2	-0.2	1.2	-0.1	1.1	0.4	1.0	-0.1
Mouth/teeth dental problems	1.5	2.3	4.8	2.0	1.9	0.4	2.2	1.8	1.9	1.4	1.7	1.7	2.1	-1.4	-1.8	1.2	-0.0	1.2	0.4	1.8	1.3	1.2	0.8	1.8	1.4	1.0	0.9	1.8
Heart attack	1.8	2.3	6.9	2.6	2.2	-0.1	2.3	-0.7	2.4	0.5	1.8	1.8	2.6	-2.1	-0.3	0.4	-0.8	0.1	-1.0	1.2	-0.9	2.4	-0.3	1.7	0.4	-0.2	-0.9	2.0
Allergy	0.1	0.2	0.7	0.2	0.1	-0.4	0.4	-0.3	0.1	-0.5	-0.0	-0.2	0.1	0.8	0.2	-0.5	-0.8	-0.8	-0.7	-0.3	-0.2	-0.5	-0.4	-0.3	0.1	-0.5	-0.8	-0.1
Pain all over the body in last month	0.4	0.4	3.1	-0.2	-0.2	0.0	-0.2	0.8	-0.2	0.6	0.1	-0.3	-0.3	1.8	-0.4	0.6	0.5	0.6	1.0	0.4	0.6	-0.7	1.0	0.2	-0.0	0.2	1.1	0.0
Diabetes (self-reported)	0.2	0.3	2.2	-0.4	-0.3	-1.5	0.3	-0.4	-0.3	-0.2	-0.4	-0.2	-0.3	0.9	0.3	-0.2	0.6	1.3	-0.1	-0.4	0.0	0.5	0.0	-0.2	0.5	-0.4	-0.1	-0.2
Hayfever/allergic rhinitis (self-reported)	0.6	0.9	1.9	-1.3	-1.3	1.0	-1.4	-0.3	-1.3	-0.6	-1.2	-1.4	-1.2	0.8	0.7	-0.6	-0.8	0.2	-0.0	-0.9	-0.6	-1.2	-0.7	-1.1	0.0	-0.4	0.1	-1.2
Medication: Ramipril	0.8	1.1	3.1	1.8	1.5	-0.8	1.7	-0.3	1.6	0.5	1.4	1.6	1.6	-0.2	-0.5	0.6	-0.1	-0.1	-0.4	0.9	-0.1	1.3	0.6	1.1	1.1	0.0	-0.6	1.4
Medication: Simvastatin	2.1	3.1	9.9	2.1	2.3	-0.6	2.0	-2.0	2.2	-1.4	1.1	0.9	2.2	-0.1	1.0	-1.5	-2.4	-0.9	-3.1	-0.3	-2.2	1.8	-2.7	0.3	-0.5	-1.0	-3.2	0.8
Fluid intelligence score	0.2	0.3	1.6	-0.2	-0.3	0.3	-0.5	0.8	-0.3	-0.6	-0.6	-0.0	-0.3	-1.0	-0.1	-0.7	-0.3	0.6	-0.6	-0.5	0.3	-0.0	-1.2	-0.4	-1.0	0.7	-0.7	-0.4
Illnesses of siblings	0.8	1.1	4.4	-1.5	-1.1	0.4	-1.3	0.6	-1.4	0.2	-0.9	-1.8	-1.6	1.4	0.2	0.1	0.9	-0.3	1.2	-0.5	0.3	-2.1	0.1	-0.7	-1.0	0.5	1.2	-0.8
Neuroticism score	1.2	2.4	6.4	-2.0	-1.9	-1.9	-2.2	-2.5	-1.9	-0.8	-1.5	-1.6	-1.8	2.5	2.2	-0.6	0.6	-1.4	0.2	-1.6	-1.3	-0.6	0.9	-1.6	0.5	-1.3	-0.6	-1.6
Weight	0.6	2.8	7.8	-1.4	-1.4	-2.6	-1.4	-2.4	-1.3	-1.7	-1.5	-2.1	-1.1	1.9	2.8	-1.6	-1.0	-2.3	-1.4	-2.0	-2.0	-0.4	-0.4	-1.6	0.2	-1.1	-1.6	-1.5
Impedance of arm (right)	0.1	0.5	2.2	0.0	0.6	0.5	0.2	1.5	0.3	0.6	0.5	-0.0	0.1	-0.7	-1.0	0.6	0.8	0.9	0.7	0.5	1.1	-0.5	-0.4	0.5	0.2	0.7	1.2	0.3
Arm fat percentage (right)	0.5	2.0	9.3	-0.4	-0.2	-2.7	-0.4	-3.0	-0.3	-1.3	-0.6	-1.9	-0.2	2.0	2.1	-1.2	-0.9	-1.5	-1.5	-1.4	-2.3	0.6	-0.3	-0.8	-0.5	-1.2	-1.5	-0.7
Trunk fat-free mass	0.2	1.1	3.2	-1.4	-1.5	-1.3	-1.5	-0.2	-1.4	-0.9	-1.2	-1.4	-1.1	0.9	1.8	-0.8	-0.4	-1.3	-0.3	-1.2	-0.4	-0.8	-0.5	-1.2	0.5	0.3	-0.5	-1.1
Hip circumference	0.5	2.1	5.7	-1.2	-1.1	-1.9	-1.3	-1.7	-1.1	-1.6	-1.4	-2.4	-1.0	1.4	2.3	-1.5	-0.9	-1.8	-1.2	-1.7	-1.8	-0.5	-0.4	-1.4	-0.5	-0.9	-1.2	-1.3
Time employed in main current job	1.8	2.1	5.3	-2.2	-2.1	-1.2	-2.3	0.4	-2.2	-0.7	-1.7	-2.3	-2.3	-0.1	0.7	-0.6	1.5	-1.7	0.6	-1.4	-0.1	-1.6	0.8	-1.6	-0.7	-0.9	0.7	-1.7
Alcohol intake versus 10 years previously	0.4	0.5	4.3	-0.5	-0.1	0.8	-0.7	-0.0	-0.3	0.5	0.3	0.0	-0.3	0.4	-0.2	0.6	0.5	1.0	0.9	0.2	1.6	-0.4	0.3	0.0	1.1	2.1	0.6	-0.1
Father’s age at death	0.8	1.0	4.8	0.8	0.9	0.3	0.9	0.5	0.9	1.3	0.8	1.3	0.9	-0.3	-0.7	1.1	0.4	1.3	1.0	1.2	1.1	0.5	-0.2	1.1	0.7	2.2	1.4	1.0
Worrier / anxious feelings	0.6	1.1	3.9	-1.5	-1.7	-0.1	-1.5	0.5	-1.6	0.4	-1.0	-0.9	-1.5	1.4	0.6	0.6	2.0	-0.4	1.5	-0.5	0.4	-0.9	1.2	-0.7	0.8	-0.5	0.9	-0.9
Frequency of tiredness / lethargy in last 2 weeks	1.9	3.1	12.1	-1.7	-1.6	-0.7	-2.1	-1.0	-1.7	1.8	-0.4	-1.0	-1.8	2.1	-0.4	1.9	3.3	-0.1	3.5	0.5	1.4	-1.0	3.3	-0.0	0.2	1.3	2.6	-0.3
Falls in the last year	1.6	2.2	5.4	-1.7	-1.6	-0.5	-1.4	-1.6	-1.6	-1.4	-1.6	-1.6	-1.6	2.3	1.9	-1.3	-1.1	-1.2	-0.8	-1.8	-1.5	-1.8	-0.3	-1.8	0.4	-1.7	-0.8	-1.7
Hair/balding pattern: Pattern 3	0.3	0.4	3.1	0.1	-0.1	-1.4	0.1	0.2	0.1	0.5	0.3	-0.7	0.3	0.4	0.4	0.7	0.2	0.8	0.4	0.2	0.9	-0.2	0.6	0.3	1.8	1.3	-0.3	0.3
Number of live births	0.2	0.2	0.8	-0.6	-0.5	-0.7	-0.6	-0.7	-0.6	-0.5	-0.4	0.1	-0.7	0.4	0.1	-0.4	-0.1	-0.6	-0.2	-0.5	-0.5	-0.1	0.5	-0.5	-0.5	-0.9	-0.3	-0.5
Forced expiratory volume in 1-second (FEV1)	0.4	1.5	4.5	-1.6	-1.3	1.6	-1.6	1.4	-1.4	-0.7	-1.2	-0.8	-1.4	-1.4	0.3	-0.9	0.1	-1.4	0.1	-1.1	-0.3	-1.6	-1.7	-1.1	-2.1	-0.2	0.7	-1.3
Pulse rate	0.4	0.7	2.7	-0.5	-0.2	-1.7	-0.5	-1.4	-0.3	-0.7	-0.4	-0.7	-0.3	1.4	1.4	-0.8	-0.3	-1.1	-0.6	-0.8	-1.3	-0.5	-0.8	-0.7	-0.5	-0.8	-0.6	-0.5
Happiness	1.5	1.8	8.3	-1.3	-1.2	1.1	-1.4	-0.5	-1.4	-1.0	-1.6	-0.9	-1.5	0.5	1.1	-1.1	0.4	-2.2	-0.3	-1.4	-1.7	-1.4	-1.1	-1.5	-2.9	-1.8	-0.5	-1.3
Noisy workplace	0.7	0.8	3.6	-0.4	-0.6	0.1	-0.7	-1.9	-0.5	-0.9	-0.4	-1.2	-0.4	1.1	1.1	-0.7	-1.0	-0.4	-0.8	-0.9	-1.1	-0.3	-0.2	-0.8	0.8	-1.6	-1.2	-0.7
Qualifications: A levels/AS levels or equivalent	0.5	1.1	4.3	-1.5	-1.4	-0.2	-1.4	0.9	-1.4	0.5	-1.0	-0.7	-1.4	0.0	-0.0	0.4	1.1	0.9	1.6	-0.2	1.2	-1.0	-0.1	-0.4	-0.5	2.1	1.3	-0.7
Serious illness, injury or assault of a close relative in last 2 years	0.3	0.4	2.0	0.3	0.3	0.8	0.2	-0.4	0.3	-0.7	-0.1	0.1	0.4	0.1	0.7	-0.8	-0.9	0.2	-1.1	-0.4	-0.6	0.1	-1.4	-0.2	-0.5	0.2	-1.0	-0.2
Mouth/teeth dental problems: Dentures	0.8	1.4	3.6	-1.3	-1.6	-0.8	-1.2	-0.6	-1.4	-1.3	-1.3	-1.1	-1.5	0.5	1.3	-1.0	-0.4	-1.9	-0.8	-1.4	-1.1	-1.3	-0.1	-1.4	-0.4	-1.7	-1.2	-1.3
Asthma	0.5	0.9	4.8	0.4	0.2	0.3	0.1	0.8	0.4	1.4	0.7	0.9	0.5	-0.6	-0.6	1.5	2.2	0.3	1.5	1.1	0.9	0.8	1.4	1.1	0.6	0.5	1.2	0.9
Medication: Ibuprofen (e.g. Nurofen)	0.6	0.8	2.8	-1.4	-1.3	0.1	-1.7	-0.3	-1.4	-0.3	-0.8	-1.4	-1.4	0.8	0.3	-0.2	0.9	-0.5	0.5	-0.8	0.0	-0.8	0.9	-0.9	-0.5	-0.6	0.2	-1.0
Medication: Cholesterol lowering	0.5	0.8	2.3	1.4	1.1	-1.1	1.4	-0.2	1.3	0.5	1.0	0.8	1.4	-0.9	-0.0	0.5	0.3	0.3	-0.3	0.7	-0.0	1.5	-0.2	1.0	1.1	0.4	-0.5	1.2
Depression (self-reported)	0.8	0.9	4.4	0.5	0.5	-0.3	0.3	-1.4	0.5	1.5	0.8	0.6	0.6	-0.0	0.1	1.5	1.0	-0.2	1.5	1.0	-0.0	0.8	2.1	1.0	1.4	0.7	1.0	1.0
Medication: Lansoprazole	1.0	1.1	2.3	0.5	0.6	0.1	0.9	-0.1	0.6	1.3	0.9	1.2	0.6	-1.5	-1.4	1.3	1.5	1.3	1.3	1.1	0.6	1.5	0.9	1.2	-0.2	0.4	1.5	1.0
Prospective memory result	1.2	1.5	6.1	1.2	0.8	-1.0	1.3	-0.3	1.1	1.6	1.1	0.5	1.3	-0.5	-0.9	1.8	0.8	0.4	1.2	1.7	0.4	1.1	2.5	1.5	1.9	0.1	0.8	1.4
Lung cancer (father)	0.3	0.3	1.5	-0.5	-0.6	-1.2	-0.6	-1.0	-0.6	-0.4	-0.5	-0.7	-0.6	0.8	0.2	-0.5	0.2	0.5	-0.2	-0.5	-0.2	0.5	0.2	-0.6	-0.5	-0.7	0.0	-0.7
Illnesses of mother	0.1	0.1	0.6	-0.4	-0.3	0.3	-0.1	-0.3	-0.3	-0.0	-0.1	-0.1	-0.2	0.4	-0.3	-0.1	-0.7	0.3	0.1	-0.0	-0.0	-0.6	0.1	-0.2	0.2	-0.2	0.4	-0.3
Forced expiratory volume in 1-second (FEV1), Best measure	0.6	2.0	5.5	-2.0	-1.9	1.8	-2.1	1.4	-2.0	-0.9	-1.6	-1.3	-2.0	-0.8	0.4	-0.9	-0.1	-1.6	0.2	-1.3	-0.2	-2.3	-0.8	-1.5	-1.3	-0.6	0.7	-1.7
Pulse wave Arterial Stiffness index	1.1	1.3	2.8	-1.5	-1.6	1.4	-1.5	1.7	-1.6	-0.7	-1.4	-1.2	-1.6	0.3	0.4	-0.7	0.5	1.0	0.1	-1.1	0.5	-1.4	-1.5	-1.3	-0.5	-0.8	0.3	-1.6
Impedance of arm (left)	0.1	0.5	3.0	-0.0	0.5	0.7	0.2	1.7	0.2	0.7	0.4	0.3	-0.1	-0.4	-1.0	0.7	0.9	0.8	0.9	0.5	1.1	-0.7	-0.4	0.4	-0.0	0.5	1.4	0.3
Arm fat mass (right)	0.7	2.9	9.9	-0.9	-0.9	-3.0	-0.9	-3.1	-0.9	-1.7	-1.2	-2.2	-0.7	2.3	2.7	-1.5	-1.0	-2.1	-1.6	-1.8	-2.5	0.2	-0.2	-1.3	-0.3	-1.4	-1.8	-1.2
Trunk predicted mass	0.2	1.1	3.2	-1.4	-1.5	-1.3	-1.5	-0.2	-1.3	-0.8	-1.2	-1.4	-1.1	0.9	1.8	-0.7	-0.4	-1.4	-0.3	-1.2	-0.4	-0.8	-0.4	-1.1	0.5	0.3	-0.5	-1.1
Standing height	0.1	1.3	4.3	-1.8	-1.5	-0.4	-1.7	2.1	-1.6	-0.2	-1.0	-0.7	-1.5	-0.2	0.7	0.0	0.6	-0.3	0.8	-0.7	1.3	-1.8	-0.7	-1.0	1.4	0.8	1.0	-1.1
Length of working week for main job	1.1	1.2	5.0	0.1	0.2	-1.0	-0.1	-1.3	0.1	-1.4	-0.5	0.5	-0.0	1.1	0.9	-1.4	-1.5	-1.2	-1.8	-0.9	-1.2	-1.1	-0.7	-0.9	-0.1	-2.1	-2.2	-0.7
Exposure to tobacco smoke at home	0.7	0.8	2.6	0.8	0.9	1.6	1.1	0.6	0.8	0.9	1.3	1.2	0.6	-0.6	-1.4	0.9	-0.0	0.7	0.6	1.0	1.3	0.2	0.9	0.8	0.8	0.8	0.8	0.7
Breastfed as a baby	1.3	1.6	6.3	1.3	1.3	2.5	1.2	1.2	1.2	0.8	1.2	1.3	1.2	-2.1	-1.6	0.8	-0.7	1.6	0.3	1.2	1.3	0.7	0.5	1.2	1.0	1.1	0.8	1.1
Tense / ‘highly strung’	0.4	0.6	3.2	0.4	0.2	-1.1	0.1	-0.0	0.3	1.2	0.6	0.9	0.4	0.6	-0.2	1.3	1.8	0.0	1.3	0.9	0.6	0.2	1.1	0.8	0.8	0.3	0.5	0.7
Seen doctor (GP) for nerves, anxiety, tension or depression	0.7	1.1	4.6	-0.8	-0.8	-1.3	-1.2	-2.1	-0.8	-0.3	-0.8	-1.3	-0.8	2.1	1.6	-0.3	0.1	-1.2	0.2	-0.8	-1.6	-0.6	-0.0	-0.8	-0.6	-0.8	-0.4	-0.6
Hair/balding pattern: Pattern 4	1.5	3.6	6.3	1.9	1.7	2.2	2.5	2.2	1.8	2.0	1.9	1.9	1.9	-1.9	-2.0	2.0	1.6	2.1	1.3	2.2	2.2	1.5	0.6	2.1	1.6	2.1	1.8	2.0
Birth weight of first child	0.5	1.0	4.6	-1.0	-1.4	0.2	-0.7	2.1	-1.2	0.8	-0.7	-0.6	-1.1	-0.7	-0.4	0.7	1.6	0.3	1.6	0.0	0.6	-0.3	0.2	-0.0	-1.3	0.9	1.9	-0.2
Peak expiratory flow (PEF)	0.5	1.1	4.4	-0.8	-0.5	1.7	-0.6	1.6	-0.6	1.0	-0.2	-0.1	-0.6	-1.2	-0.6	0.8	1.3	0.2	1.7	0.4	1.0	-0.6	-0.6	0.3	-1.4	1.7	2.1	-0.1
Pulse wave reflection index	0.5	0.6	2.0	-0.8	-1.1	1.4	-1.0	1.0	-1.0	-0.7	-0.8	-0.4	-1.0	0.3	-0.2	-0.6	0.1	1.1	-0.2	-0.7	1.0	-0.5	0.0	-0.8	-0.2	0.1	-0.1	-1.0
Ever highly irritable/argumentative for 2 days	1.1	1.3	2.9	0.9	0.4	0.3	0.7	0.7	0.7	1.7	1.0	0.4	0.8	-0.3	-1.1	1.7	1.7	1.0	1.6	1.6	1.2	1.3	1.6	1.4	0.2	1.2	1.2	1.3
Loud music exposure frequency	0.9	1.0	4.8	0.7	0.8	0.2	0.4	0.8	0.7	1.5	1.2	0.2	0.5	0.2	-1.1	1.5	2.2	-0.0	1.5	1.2	0.9	0.2	1.0	1.2	-0.5	0.5	1.4	1.1
Qualifications: O levels/GCSEs or equivalent	0.3	0.5	2.3	-1.0	-0.9	0.7	-0.7	0.7	-1.0	-0.2	-0.8	-0.3	-0.9	-0.5	-0.1	-0.3	0.5	0.3	0.4	-0.4	1.1	-0.5	0.4	-0.5	-0.8	1.5	0.2	-0.7
Mouth/teeth dental problems: Bleeding gums	0.3	0.4	1.9	-0.4	0.1	0.9	-0.5	-0.3	-0.3	0.6	0.0	-0.1	-0.6	-0.6	-0.2	0.5	1.4	0.9	1.1	0.1	0.6	-0.0	0.2	-0.0	-0.5	0.7	0.9	-0.1
Blood clot in the leg (DVT)	0.6	0.7	3.8	0.4	0.4	-0.3	0.5	0.8	0.4	1.1	0.8	1.0	0.3	-0.3	-1.1	1.2	1.2	2.0	1.1	0.9	0.9	0.5	0.7	0.8	0.7	0.2	1.0	0.7
Medication: Paracetamol	0.4	0.6	2.2	0.7	0.4	-0.5	0.6	-0.4	0.6	1.0	1.0	1.2	0.7	-0.1	-0.3	1.1	0.7	0.5	0.7	0.9	0.6	0.9	1.3	1.0	1.5	0.4	0.2	0.9
Headache pain in last month	0.3	0.6	1.5	0.3	0.5	0.7	-0.0	0.5	0.3	1.1	0.7	1.1	0.0	-0.2	-1.2	1.0	0.7	0.9	1.2	0.9	0.8	-0.1	0.7	0.6	-1.2	0.7	0.9	0.5
Medication for cholesterol, blood pressure or diabetes	0.7	1.1	2.6	-1.6	-1.1	1.0	-1.5	0.4	-1.4	-0.8	-1.4	-1.0	-1.4	1.0	0.7	-1.0	-0.5	0.1	-0.1	-1.1	-0.4	-1.3	-1.5	-1.2	-1.3	-0.0	0.0	-1.5
Glaucoma (self-reported)	0.4	0.5	2.4	-0.2	0.1	-0.4	-0.2	-1.4	-0.1	-0.6	-0.5	-0.9	-0.1	1.5	1.1	-0.8	-0.5	-1.0	-0.6	-0.7	-1.0	-0.9	-0.5	-0.6	-0.7	0.2	-0.4	-0.4
Gout (self-reported)	0.5	0.6	2.6	0.1	0.0	-0.3	0.3	-0.3	0.1	-1.2	-0.4	-0.1	0.2	-0.1	0.8	-1.0	-0.9	-0.7	-1.6	-0.8	-0.7	0.2	-0.3	-0.6	1.5	-1.4	-1.6	-0.4
Hypothyroidism/myxoedema (self-reported)	0.4	0.7	4.1	0.4	0.1	-2.0	0.5	-0.0	0.2	1.0	0.1	0.4	0.4	-0.3	-0.1	1.0	1.3	0.9	1.1	0.8	0.1	1.2	0.8	0.9	-0.2	1.5	0.6	0.7
Medication: Amlodipine	0.3	0.5	2.5	-0.3	-0.6	-0.1	-0.3	-0.2	-0.4	-0.8	-0.5	-0.7	-0.3	0.0	0.9	-0.6	-0.2	-1.6	-0.8	-0.7	-0.4	-0.4	0.2	-0.6	1.4	-1.0	-0.8	-0.4
Medication: Ventolin 100micrograms inhaler	1.8	2.3	7.3	-2.4	-2.2	0.3	-2.7	-0.3	-2.3	-0.7	-1.6	-1.7	-2.4	1.1	1.2	-0.6	1.1	-1.3	0.7	-1.5	-0.4	-1.9	-0.7	-1.7	-1.2	-1.0	0.4	-1.9
Birth weight	1.5	3.2	11.0	-0.2	-0.5	1.3	-0.1	3.3	-0.2	2.1	0.7	0.5	0.0	-0.2	-1.1	2.2	1.6	3.1	2.7	1.4	3.1	0.6	0.3	1.1	2.5	2.9	3.0	0.7
Chronic bronchitis/emphysema (mother)	1.1	1.3	2.7	1.5	1.6	-1.0	1.4	-1.4	1.5	0.9	1.5	1.6	1.6	-0.4	0.1	0.8	-0.4	0.6	0.1	1.0	0.1	1.4	0.6	1.3	1.5	1.2	-0.3	1.4
High blood pressure (siblings)	0.7	0.9	4.5	1.3	0.8	-0.8	0.9	-1.5	1.1	-0.1	0.8	1.5	1.3	-1.1	-0.0	-0.0	-0.5	-0.3	-1.0	0.4	-0.2	2.1	1.2	0.5	1.2	-0.1	-1.1	0.7
Forced vital capacity (FVC), Best measure	0.4	1.6	5.1	-1.7	-1.6	2.2	-2.0	2.3	-1.7	-0.4	-1.0	-0.9	-1.7	-1.3	-0.2	-0.4	0.0	-0.9	0.6	-0.9	0.6	-2.1	-0.4	-1.1	-0.6	-0.1	1.2	-1.3
Body fat percentage	1.1	4.3	15.0	-0.8	-0.6	-3.2	-0.7	-3.9	-0.7	-2.2	-1.2	-2.1	-0.6	2.7	3.0	-2.1	-1.8	-2.3	-2.4	-2.2	-3.4	0.4	-0.6	-1.6	-0.6	-2.5	-2.4	-1.4
Leg fat percentage (right)	1.1	4.1	20.6	-0.1	-0.1	-3.7	-0.0	-4.5	-0.1	-1.9	-0.7	-1.7	0.1	2.0	2.6	-1.9	-1.8	-2.3	-2.4	-1.7	-3.8	1.5	0.1	-1.0	-0.9	-2.6	-2.4	-0.7
Arm fat-free mass (right)	0.5	2.3	5.5	-1.7	-1.8	-1.5	-1.8	-1.2	-1.7	-1.6	-1.7	-1.6	-1.4	1.4	2.3	-1.4	-0.8	-2.3	-1.0	-1.9	-1.5	-1.1	-0.2	-1.8	0.1	-1.2	-1.2	-1.7
Exposure to tobacco smoke outside home	0.3	0.5	1.9	-0.7	-0.7	0.3	-0.6	-1.3	-0.6	-0.7	-0.6	-0.8	-0.5	-0.2	0.9	-0.5	-0.4	0.1	-0.5	-0.7	-0.1	0.4	0.1	-0.7	1.4	-0.3	-0.8	-0.6
Comparative body size at age 10	0.4	1.1	5.6	-0.9	-0.7	-1.1	-0.6	0.3	-0.8	0.8	-0.1	0.0	-0.9	0.7	-0.8	0.8	1.8	1.1	1.5	0.3	2.0	-0.5	1.2	-0.0	-0.8	2.4	1.4	-0.3
Number of full brothers	0.2	0.2	1.1	0.6	0.5	0.8	0.7	0.3	0.6	0.2	0.5	0.4	0.6	0.1	-0.4	0.3	-0.1	-0.1	-0.1	0.4	-0.0	0.6	0.6	0.4	1.0	-0.6	0.2	0.5
Worry too long after embarrassment	0.3	0.6	3.4	-0.7	-0.7	-0.3	-0.4	-1.4	-0.6	0.2	-0.0	-0.5	-0.5	1.0	0.9	0.4	-0.3	-0.6	0.6	-0.4	-0.4	-0.1	1.7	-0.2	1.8	-0.4	0.0	-0.3
Seen a psychiatrist for nerves, anxiety, tension or depression	0.7	0.9	4.1	-0.6	-0.5	-0.9	-1.0	-0.5	-0.5	1.3	-0.0	-0.6	-0.5	1.1	0.2	1.3	1.6	-0.1	2.0	0.5	0.3	-0.5	1.7	0.4	-0.2	1.4	1.7	0.3
Wheeze or whistling in the chest in last year	1.3	2.3	13.3	0.4	0.3	-0.5	0.1	-0.1	0.3	2.2	1.2	0.7	0.2	0.6	-1.4	2.3	2.8	0.5	2.5	1.6	1.3	1.0	3.6	1.4	0.8	0.9	1.9	1.2
Number of children fathered	1.0	1.2	3.0	1.7	1.6	-1.2	1.7	0.1	1.6	0.8	1.3	1.2	1.5	-1.1	-0.6	0.7	0.2	-0.2	0.0	1.1	-0.2	1.5	0.7	1.3	-0.3	-0.2	-0.0	1.5
Reason for reducing amount of alcohol drunk: Health precaution	1.0	1.1	6.8	0.7	0.5	2.4	0.6	2.3	0.6	0.6	0.5	0.5	0.6	-2.6	-0.9	0.7	0.4	0.7	0.4	0.7	1.2	0.1	-0.6	0.7	1.3	0.6	0.8	0.6
Age at first live birth	0.5	0.9	3.9	-0.9	-0.6	1.8	-0.9	2.0	-0.8	0.0	-0.8	-0.2	-0.9	-0.4	-0.3	-0.2	-0.1	1.4	0.6	-0.1	0.9	-1.4	-1.5	-0.4	-0.9	1.1	0.7	-0.8
Pulse wave peak to peak time	1.2	1.4	2.7	1.5	1.5	-1.4	1.4	-1.5	1.6	0.9	1.5	1.3	1.6	-0.4	-0.5	0.9	-0.3	-0.7	0.2	1.3	-0.2	1.4	1.5	1.4	0.7	1.0	-0.0	1.6
Health satisfaction	0.1	0.1	0.7	0.2	-0.1	0.8	0.3	-0.3	0.1	0.1	0.1	0.3	0.2	-0.5	-0.1	0.1	-0.0	0.2	-0.1	0.2	-0.1	0.8	0.2	0.2	0.1	0.0	-0.4	0.3
Shortness of breath walking on level ground	0.7	0.8	2.2	-1.2	-1.5	0.3	-1.4	0.4	-1.4	-0.6	-1.0	-0.9	-1.3	-0.3	0.2	-0.5	1.3	-1.1	0.1	-0.9	0.0	-0.7	-0.3	-1.1	-0.8	-1.0	-0.0	-1.1
Qualifications: College or University degree	0.8	2.5	8.6	-1.4	-1.4	0.8	-1.4	2.3	-1.5	1.5	-0.9	-0.4	-1.6	-1.0	-1.5	1.2	2.2	1.6	2.9	0.5	2.0	-1.5	0.1	0.0	-2.1	1.8	2.9	-0.5
Eye problems/disorders: None of the above	0.8	0.9	2.8	0.0	0.2	1.1	-0.0	1.0	0.1	1.2	0.7	-0.6	0.2	-0.2	-0.6	1.3	1.1	1.3	1.4	0.9	1.4	0.5	1.3	0.9	1.7	0.7	1.3	0.6
Mouth/teeth dental problems: Loose teeth	0.3	0.4	2.0	0.1	0.3	-0.1	-0.1	-1.4	0.2	-0.3	-0.1	0.6	0.2	0.9	1.0	-0.3	-1.0	-0.7	-0.4	-0.3	-1.0	-0.3	-0.9	-0.2	-0.3	-0.1	-0.6	-0.0
Emphysema/chronic bronchitis	0.4	0.5	2.6	0.7	0.6	1.0	0.3	0.4	0.6	0.7	0.7	0.9	0.5	-0.2	-0.9	0.7	0.5	-0.9	0.5	0.8	0.7	-0.7	1.6	0.5	0.2	0.1	0.1	0.6
Medication for pain relief, constipation, heartburn	0.5	0.8	4.8	-0.3	-0.0	1.2	-0.2	0.9	-0.2	-1.0	-0.6	-0.9	-0.4	-0.3	-0.1	-1.1	-1.3	-0.6	-1.1	-0.7	-0.3	-1.3	-2.2	-0.8	-1.1	-0.5	-0.5	-0.8
Neck or shoulder pain in last month	3.4	4.9	8.5	-2.9	-2.8	-1.3	-2.8	-1.0	-2.9	-2.3	-2.8	-2.3	-2.9	2.5	2.4	-2.2	-0.3	-1.9	-1.1	-2.7	-1.2	-2.8	-1.1	-2.9	-1.0	-1.5	-1.1	-2.9
Medication: Blood pressure	0.4	0.7	2.4	1.0	0.4	-1.6	0.9	-0.5	0.7	0.5	0.7	0.8	0.9	-0.9	-0.2	0.7	0.6	-0.6	0.1	0.6	0.3	0.9	1.5	0.7	1.4	-0.4	0.0	0.9
Angina (self-reported)	2.5	3.3	10.0	2.7	1.9	-0.4	2.7	-0.2	2.3	1.4	2.1	2.2	2.8	-1.5	-0.6	1.5	0.3	2.0	0.1	1.8	0.4	3.0	-0.3	2.1	3.2	0.5	-0.1	2.2
Migraine (self-reported)	0.8	1.0	4.5	0.4	0.4	0.8	0.1	-0.3	0.4	1.3	0.9	0.2	0.3	-1.4	-1.3	1.3	2.1	0.6	1.5	1.0	1.1	0.7	1.6	0.8	0.1	0.7	1.4	0.7
Medication: Ibuprofen	0.7	0.8	2.7	-1.3	-1.2	-0.0	-1.7	-0.6	-1.3	-0.5	-1.0	-1.4	-1.3	0.6	0.6	-0.5	0.2	-0.5	0.2	-1.0	-0.6	-0.7	0.3	-1.0	-0.7	-1.1	-0.1	-1.1
Medication: Allopurinol	0.8	1.1	2.2	-1.2	-1.2	-0.2	-1.0	-0.2	-1.2	-1.5	-1.3	-1.2	-1.1	0.6	1.1	-1.3	-0.5	-0.9	-1.1	-1.4	-0.3	-0.9	-0.4	-1.5	0.7	-0.7	-1.1	-1.4
Medication: Omeprazole	1.0	1.1	4.3	-0.6	-0.7	1.5	-0.4	1.1	-0.7	1.1	-0.1	-0.8	-0.6	-0.9	-0.9	1.0	1.7	1.7	1.9	0.6	1.4	0.1	0.8	0.4	-0.4	1.3	2.1	0.0
Medication: Seretide 50 evohaler	0.8	1.0	3.2	-1.0	-1.2	0.3	-1.3	-0.2	-1.2	-0.4	-0.9	-1.8	-1.3	0.0	0.3	-0.5	0.6	-1.6	0.2	-0.8	-0.7	-1.1	0.3	-0.8	-1.6	-1.6	0.2	-1.0
Mean time to correctly identify matches	0.7	1.3	3.1	1.2	1.2	0.5	1.4	1.3	1.2	1.0	1.4	1.3	1.1	-1.1	-1.8	1.0	0.4	1.5	0.4	1.4	1.3	1.2	0.7	1.3	0.7	0.6	0.8	1.3
Heart disease (mother)	0.1	0.2	1.4	0.1	0.0	-0.3	-0.1	0.7	0.0	0.2	0.1	0.1	0.0	-0.8	-0.4	0.3	0.1	1.2	0.2	0.2	0.5	0.6	0.3	0.2	0.5	0.0	-0.1	0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.4	0.5	1.7	0.2	0.6	1.3	0.5	1.2	0.4	0.8	0.7	0.1	0.2	-0.2	-1.2	0.8	0.5	0.8	0.8	0.8	1.2	0.3	0.2	0.7	-0.1	0.9	0.9	0.5
Whole body fat mass	0.9	3.7	12.2	-1.1	-0.9	-3.1	-1.0	-3.5	-0.9	-2.1	-1.3	-2.2	-0.8	2.5	3.0	-1.9	-1.6	-2.3	-2.0	-2.1	-2.9	0.1	-0.4	-1.6	-0.2	-1.8	-2.2	-1.4
Leg fat mass (right)	1.1	4.1	16.3	-0.9	-0.8	-3.5	-0.8	-4.0	-0.8	-2.0	-1.2	-2.2	-0.6	2.4	3.0	-1.9	-1.6	-2.5	-2.0	-2.0	-3.3	0.6	0.0	-1.5	-0.3	-2.2	-2.2	-1.3
Arm predicted mass (right)	0.3	1.8	4.8	-1.4	-1.6	-1.5	-1.6	-1.2	-1.4	-1.4	-1.4	-1.4	-1.2	1.4	2.2	-1.2	-0.8	-1.9	-0.9	-1.6	-1.2	-0.8	-0.1	-1.5	0.3	-0.9	-1.2	-1.4
Pulse rate, automated reading	0.1	0.2	1.6	-0.0	0.3	-1.3	-0.2	0.2	0.2	-0.2	0.2	0.1	-0.0	-0.2	0.1	-0.3	0.5	-0.2	-0.3	-0.0	-0.4	-0.3	-0.8	-0.1	-1.2	-1.0	-0.0	-0.2
Alcohol intake frequency.	0.8	1.8	4.6	-1.4	-1.4	0.7	-1.4	-1.4	-1.4	-1.3	-1.3	-1.9	-1.6	1.2	1.0	-1.4	0.2	-1.7	-0.7	-1.4	-1.0	-1.6	-0.2	-1.6	-2.1	-1.2	-1.0	-1.5
Comparative height size at age 10	0.2	1.3	10.1	-0.7	-0.7	1.1	-0.5	3.2	-0.6	0.7	0.1	0.3	-0.5	-0.8	-0.4	0.9	0.6	0.5	1.2	0.4	2.0	-1.4	-0.8	-0.0	2.2	0.8	1.6	-0.2
Number of full sisters	0.4	0.5	3.8	0.4	0.1	0.2	0.2	-0.7	0.2	0.9	0.4	-0.1	0.3	0.4	-0.6	1.0	0.2	0.2	0.9	0.8	0.7	-0.2	2.0	0.6	1.4	0.7	0.5	0.6
Suffer from ‘nerves’	0.6	1.0	5.7	-0.8	-1.0	-1.2	-1.1	0.7	-0.9	0.9	-0.3	0.3	-0.9	1.0	-0.1	1.1	2.4	-0.2	1.7	0.3	0.8	-0.5	1.3	-0.1	1.1	-0.3	1.1	-0.3
Overall health rating	0.1	0.3	1.4	0.4	0.2	-0.6	0.3	-0.8	0.3	0.1	0.5	0.7	0.4	-0.2	0.3	0.3	-0.0	0.3	-0.2	0.1	0.1	1.0	0.8	0.4	1.2	-0.0	-0.6	0.6
Chest pain or discomfort	1.8	2.5	8.5	-0.8	-1.0	2.4	-1.1	2.6	-1.0	1.8	0.1	-0.9	-1.2	-0.9	-1.8	1.9	2.9	0.0	2.9	0.9	2.0	-0.7	1.9	0.3	-0.3	0.7	2.7	0.1
Had major operations	0.9	1.1	3.3	0.7	1.2	-0.6	0.8	0.5	0.9	0.7	1.0	1.8	0.7	-0.3	-1.5	0.8	0.9	1.8	0.4	1.0	1.7	1.0	1.2	0.9	0.6	1.5	0.1	0.8
Age at last live birth	0.6	0.8	2.8	-1.4	-1.0	0.4	-1.4	1.0	-1.2	0.2	-1.0	-0.4	-1.3	1.3	0.2	0.1	0.5	-0.4	1.2	-0.2	0.1	-1.7	-0.5	-0.6	-1.3	0.3	0.9	-1.0
Family relationship satisfaction	3.5	4.4	9.3	-2.1	-2.3	0.0	-2.2	-1.8	-2.3	-2.2	-2.7	-2.3	-2.2	0.8	1.8	-2.2	-0.7	-3.0	-1.3	-2.5	-2.8	-1.2	-0.8	-2.4	-3.0	-2.5	-1.2	-2.2
Leg pain on walking	0.3	0.4	2.3	-0.3	-0.1	-0.7	-0.1	-0.2	-0.3	-0.5	-0.6	-0.1	-0.3	1.5	0.9	-0.6	0.3	-0.9	-0.4	-0.6	-0.3	-0.6	-1.4	-0.6	-0.7	0.2	-0.6	-0.6
Qualifications: NVQ or HND or HNC or equivalent	3.7	4.4	14.5	-0.2	-0.3	-1.1	-0.3	-2.8	-0.2	-2.5	-1.2	-1.1	-0.2	2.3	2.6	-2.6	-3.0	-2.7	-3.0	-2.0	-3.8	-0.4	-1.8	-1.5	-1.9	-2.6	-3.5	-1.0
Commuting to job workplace: Car/motor vehicle	0.9	1.0	1.9	-1.1	-1.0	1.3	-1.0	-0.1	-1.1	-1.2	-0.8	-1.4	-1.2	-1.0	0.1	-1.2	-1.3	-0.2	-0.8	-1.2	-0.4	-1.2	-0.4	-1.1	-1.3	-1.0	-0.4	-1.2
Illness, injury, bereavement, stress in last 2 years	0.2	0.3	1.7	0.5	0.3	-1.2	0.5	0.2	0.4	-0.0	0.1	0.9	0.4	-0.4	-0.4	-0.2	-0.1	0.4	-0.3	0.3	-0.4	0.8	-0.8	0.3	-1.3	-0.2	-0.2	0.3
Medication: Aspirin	1.2	1.5	4.8	1.4	1.1	-1.0	1.6	-0.2	1.4	1.1	1.0	1.8	1.6	0.3	0.1	1.2	0.3	2.2	0.4	1.2	0.3	1.9	0.7	1.5	1.8	1.3	-0.1	1.5
Supplements: Vitamin C	0.3	0.4	1.7	-0.0	0.2	0.7	-0.2	0.7	0.1	0.9	0.2	-0.4	-0.1	-0.3	-0.4	1.0	1.3	-0.2	1.2	0.6	0.8	-1.0	-0.2	0.3	0.4	0.4	1.1	0.1
Knee pain experienced in last month	0.2	0.2	0.8	-0.4	-0.8	0.9	-0.3	-0.2	-0.6	-0.5	-0.7	-0.7	-0.4	-0.4	0.5	-0.5	-0.5	0.5	-0.3	-0.5	-0.2	-0.1	-0.8	-0.4	-0.2	0.5	-0.0	-0.5
Hypertension (Self-reported)	0.3	0.7	4.0	1.0	0.6	-1.3	0.6	-0.6	0.8	-0.6	0.4	0.4	0.9	-0.8	0.6	-0.5	-0.2	-1.4	-1.3	-0.2	-1.2	0.5	0.2	0.1	0.4	-2.0	-1.3	0.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.8	0.9	2.6	0.4	0.2	-0.4	0.7	-0.3	0.4	1.4	0.7	0.4	0.5	-0.8	-1.0	1.3	1.3	1.5	1.5	1.2	0.6	1.1	0.5	1.2	-0.6	1.6	1.3	0.8
Illnesses of father: Heart disease	1.8	2.5	8.2	1.5	1.7	0.2	1.6	0.5	1.6	1.7	1.7	2.2	1.6	-0.7	-0.9	1.8	0.7	1.7	1.1	1.7	1.7	1.5	1.2	1.7	2.9	2.4	0.8	1.7
Illnesses of siblings: Diabetes	1.2	1.5	4.5	0.3	0.1	-1.1	0.7	-1.7	0.3	-1.3	-0.3	-0.2	0.5	1.9	1.8	-1.4	-2.1	-0.6	-1.9	-0.9	-1.9	0.0	-1.4	-0.6	-0.1	-1.2	-2.1	-0.5
Smoking status: Previous	0.2	0.3	1.1	0.6	0.6	0.9	0.6	0.9	0.6	-0.4	0.1	0.1	0.4	0.3	-0.2	-0.4	-0.3	0.0	-0.9	0.0	-0.5	0.2	-1.1	0.0	-0.7	-1.0	-0.9	0.1
Forced expiratory volume in 1-second (FEV1), predicted	0.5	0.9	4.2	-1.5	-1.1	0.6	-1.3	1.0	-1.3	-0.2	-0.7	-2.0	-1.4	0.5	0.7	-0.1	0.3	-1.1	0.6	-0.8	0.5	-1.5	0.3	-0.9	0.8	0.5	0.6	-0.9
Whole body fat-free mass	0.3	1.6	3.8	-1.8	-1.8	-1.2	-1.9	-0.3	-1.7	-1.0	-1.5	-1.8	-1.5	1.1	1.9	-0.8	-0.2	-1.5	-0.2	-1.4	-0.4	-1.1	-0.3	-1.4	0.5	0.2	-0.5	-1.4
Leg fat-free mass (right)	0.3	1.4	3.5	-1.9	-1.8	-0.8	-1.8	0.1	-1.8	-0.8	-1.5	-1.8	-1.6	1.1	1.7	-0.7	-0.1	-1.2	0.1	-1.3	0.0	-1.3	-0.2	-1.3	0.4	0.5	-0.2	-1.4
Arm fat percentage (left)	0.6	2.2	9.5	-0.5	-0.3	-2.7	-0.5	-3.1	-0.4	-1.4	-0.8	-1.8	-0.3	2.2	2.2	-1.4	-1.0	-1.6	-1.5	-1.4	-2.4	0.5	-0.4	-0.9	-0.7	-1.4	-1.5	-0.8
Average weekly red wine intake	0.5	0.7	2.0	-1.1	-1.1	0.7	-1.2	0.5	-1.1	-0.2	-1.2	-0.7	-1.1	-1.2	0.3	-0.4	0.5	-0.2	0.5	-0.6	-0.1	-0.5	-0.9	-0.7	-1.4	0.3	0.7	-0.9
Handedness (chirality/laterality): Left-handed	0.2	0.2	1.7	0.1	0.3	0.2	0.3	-0.7	0.2	-0.4	-0.0	-0.2	0.2	-0.6	0.7	-0.6	-0.4	-0.1	-0.6	-0.3	-1.0	0.4	-1.3	-0.1	-0.8	-0.0	-0.2	0.0
Mood swings	0.5	1.0	10.2	0.5	0.9	-1.7	0.4	-3.2	0.7	-0.0	0.5	0.2	0.6	1.6	0.7	-0.1	-0.1	-0.4	-0.4	-0.0	-0.7	1.0	1.2	0.3	-0.3	0.4	-1.4	0.5
Loneliness, isolation	0.7	0.9	2.4	-1.2	-0.9	-0.4	-1.6	-1.3	-1.1	-0.7	-0.8	-1.0	-1.1	1.4	1.4	-0.7	-0.5	-1.1	-0.1	-1.1	-1.1	-1.0	-0.0	-1.0	-0.5	-0.6	-0.2	-1.1
Long-standing illness, disability or infirmity	2.4	3.7	11.9	0.7	0.7	-1.3	0.7	-0.1	0.7	2.7	1.5	0.9	0.9	-0.1	-1.0	2.8	2.8	2.8	3.0	1.9	2.4	1.9	1.7	2.0	1.5	3.5	2.5	1.6
Ever had bowel cancer screening	2.7	3.1	7.0	1.1	0.8	1.3	1.3	2.6	1.0	1.8	1.4	1.1	1.0	-2.5	-1.9	1.8	2.3	2.6	1.6	1.7	2.6	1.5	0.2	1.7	0.8	2.5	2.3	1.5
Diabetes diagnosed by doctor	0.2	0.3	3.5	-0.2	-0.2	-1.3	0.4	0.0	-0.2	0.0	-0.2	-0.1	-0.2	0.5	-0.1	0.1	0.8	1.9	0.1	-0.1	0.6	0.6	0.3	0.0	0.3	0.3	0.1	-0.0
Ever had stillbirth, spontaneous miscarriage or termination	1.2	1.3	4.9	-0.2	0.0	0.8	-0.3	0.7	-0.1	1.3	0.6	-0.2	-0.2	-0.6	-1.4	1.4	2.2	1.4	1.8	0.9	2.0	1.2	1.1	0.7	0.5	1.5	1.9	0.5
Friendships satisfaction	1.2	1.4	4.8	-0.0	0.0	-0.3	-0.2	-1.8	-0.0	-1.5	-0.6	-0.5	-0.1	-0.0	0.6	-1.6	-1.4	-1.7	-1.9	-1.1	-2.2	-0.1	-1.1	-0.9	-1.8	-2.1	-1.5	-0.7
Qualifications: nursing, teaching	0.7	1.1	2.7	-0.5	-0.7	-1.0	-0.8	-1.6	-0.7	-1.3	-1.0	-0.7	-0.6	0.3	1.3	-1.3	-1.7	-0.3	-1.2	-1.2	-1.1	-0.8	-1.2	-1.1	-0.7	-0.5	-1.6	-1.0
Commuting to job workplace: Walk	0.9	1.0	4.0	-1.2	-0.9	-0.6	-1.2	0.5	-1.0	-0.9	-1.2	-0.4	-1.0	1.6	1.6	-0.9	0.0	-0.5	-0.4	-1.1	-0.1	-1.1	-2.0	-1.1	-0.3	0.5	-0.7	-1.1
Eye problems/disorders: Cataract	0.9	1.1	4.1	1.3	1.2	-0.4	1.4	-0.5	1.2	-0.2	0.6	2.0	1.3	-1.8	0.2	-0.4	-1.1	-0.3	-1.0	0.4	-0.7	1.1	-1.5	0.5	-0.8	1.0	-1.0	0.8
Mouth/teeth dental problems: Mouth ulcers	2.7	4.3	12.2	-2.4	-2.1	-1.6	-2.5	-2.1	-2.2	-2.0	-2.3	-2.5	-2.3	3.5	2.2	-1.9	-0.4	-1.6	-1.0	-2.3	-1.8	-2.2	-1.1	-2.4	-1.8	-1.4	-1.1	-2.4
Medication for cholesterol	0.5	0.7	2.7	-1.4	-1.6	0.1	-1.2	-0.2	-1.5	-0.2	-1.2	-1.4	-1.5	0.1	0.2	0.0	0.8	-0.3	0.7	-0.6	0.3	-0.7	0.9	-0.8	0.2	-0.1	0.3	-0.9
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.5	0.6	2.0	1.2	0.9	0.0	1.3	-0.4	1.1	0.3	0.8	1.4	1.1	0.8	-0.1	0.4	-0.4	0.2	-0.4	0.7	0.1	1.1	0.3	0.8	1.2	0.4	-0.5	0.9
Back pain experienced in last month	0.6	0.8	3.0	-0.1	-0.3	0.2	-0.0	1.2	-0.2	1.3	0.1	0.1	-0.2	-0.9	-0.8	1.2	1.6	0.2	1.7	0.9	1.1	0.2	1.3	0.7	-0.5	1.2	1.4	0.6
Mineral and other dietary supplements	1.0	1.3	10.0	0.3	0.2	-3.2	0.3	-2.8	0.3	-0.3	-0.1	0.2	0.3	1.2	0.5	-0.3	-0.6	-1.2	-0.5	-0.2	-1.6	0.8	2.3	0.1	-1.0	-0.7	-1.0	0.3
Breast cancer (self-reported)	0.9	1.1	3.5	0.1	-0.1	-1.8	0.2	-1.0	0.1	-1.1	-0.8	0.1	0.3	0.6	1.6	-1.2	-1.2	-1.3	-1.6	-0.8	-1.8	-0.2	-1.6	-0.5	-0.7	-0.8	-1.9	-0.3
Asthma (self-reported)	0.6	1.1	6.9	0.1	0.0	0.1	-0.1	1.0	0.1	1.6	0.5	0.7	0.2	-0.7	-0.7	1.7	2.6	0.2	1.9	1.1	1.0	0.6	1.6	1.0	0.3	0.6	1.6	0.7
Osteoporosis (self-reported)	4.3	5.3	13.0	0.6	1.1	0.6	0.6	3.0	0.8	2.9	1.6	2.5	0.5	-2.1	-3.2	2.8	3.2	3.2	3.2	2.5	3.6	1.1	1.4	2.0	0.3	2.9	3.6	1.6
Osteoarthritis (self-reported)	0.3	0.4	4.0	-0.3	-0.2	-0.9	0.0	-1.2	-0.2	-0.5	-0.3	-0.5	-0.1	2.0	0.7	-0.4	-0.7	1.0	-0.5	-0.4	-0.2	0.7	-0.4	-0.3	0.4	0.2	-0.5	-0.4
Medication: Aspirin	1.4	1.8	6.9	1.4	1.1	-0.6	1.6	-0.1	1.3	1.4	1.2	2.0	1.6	-0.0	-0.2	1.4	0.6	2.6	0.8	1.4	0.8	2.0	0.5	1.6	1.8	1.8	0.3	1.6
Medication: Gliclazide	0.2	0.2	0.9	0.2	0.2	0.0	0.3	-0.8	0.2	-0.5	0.0	-0.2	0.2	-0.3	0.6	-0.5	-1.0	-0.4	-0.7	-0.3	-0.8	-0.1	0.0	-0.1	-0.7	-0.5	-0.8	0.0
Illnesses of father: None of the above (group 1)	1.7	2.1	6.3	-1.7	-1.8	-1.9	-1.5	-0.7	-1.8	-1.3	-1.9	-1.9	-1.7	2.0	1.1	-1.2	-0.0	-0.8	-0.5	-1.6	-1.6	-0.3	0.2	-1.6	-0.9	-2.5	-0.4	-1.6
Smoking status: Current	0.3	0.4	2.2	-0.5	-0.8	-1.3	-0.9	-0.8	-0.6	-0.1	-0.5	-0.6	-0.4	0.9	1.1	-0.2	-0.5	-1.5	0.2	-0.5	-0.9	-0.3	0.4	-0.2	-0.4	0.2	-0.1	-0.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.2	0.4	2.8	0.7	0.5	1.6	0.6	-0.0	0.6	-0.1	0.4	0.8	0.7	-1.7	-0.6	-0.3	-0.6	-0.6	-0.6	0.2	-0.4	0.5	-0.4	0.3	-0.6	-0.6	-0.0	0.3
Whole body water mass	0.3	1.6	3.9	-1.8	-1.8	-1.3	-1.9	-0.5	-1.7	-1.0	-1.5	-1.9	-1.5	1.2	2.0	-0.9	-0.3	-1.6	-0.3	-1.5	-0.5	-1.1	-0.3	-1.4	0.3	0.0	-0.5	-1.4
Leg predicted mass (right)	0.3	1.4	3.5	-1.9	-1.8	-0.9	-1.8	0.1	-1.8	-0.8	-1.5	-1.8	-1.6	1.1	1.7	-0.7	-0.0	-1.2	0.1	-1.3	0.0	-1.4	-0.2	-1.3	0.4	0.6	-0.2	-1.4
Arm fat mass (left)	0.7	3.0	10.0	-1.0	-0.9	-3.0	-1.0	-3.2	-0.9	-1.7	-1.2	-2.2	-0.8	2.3	2.6	-1.6	-1.0	-2.2	-1.6	-1.8	-2.5	0.1	-0.1	-1.4	-0.5	-1.6	-1.8	-1.2
Number of self-reported non-cancer illnesses	3.3	5.7	9.9	2.6	2.5	0.5	2.3	0.5	2.6	3.0	2.9	2.6	2.7	-2.2	-1.8	3.0	1.2	2.7	2.0	3.0	1.8	2.7	2.0	3.1	2.2	2.5	1.7	3.1
Average weekly champagne plus white wine intake	0.2	0.3	1.6	-0.3	-0.3	-0.2	-0.4	0.7	-0.3	-0.5	-0.4	0.3	-0.4	-1.2	-0.3	-0.6	-0.4	1.3	-0.4	-0.3	0.1	-0.2	-0.7	-0.3	-1.1	0.2	-0.4	-0.3
Miserableness	0.6	1.1	5.5	-1.1	-1.0	-1.3	-1.1	-2.1	-1.0	-0.2	-0.6	-0.4	-0.9	2.3	1.4	-0.1	-0.2	-1.0	0.4	-0.8	-0.8	-0.1	1.6	-0.8	0.7	-0.0	0.1	-0.7
Guilty feelings	1.2	1.7	4.3	-1.3	-1.3	-1.0	-1.1	-1.9	-1.3	-1.2	-1.2	-2.1	-1.4	1.6	1.4	-1.0	-0.4	-1.9	-0.6	-1.5	-1.3	-0.9	0.6	-1.4	-0.4	-1.6	-1.4	-1.3
Wears glasses or contact lenses	1.5	1.7	5.0	1.6	1.3	0.3	1.3	2.0	1.5	1.0	1.5	1.1	1.4	-2.2	-1.5	0.9	0.1	2.0	0.3	1.4	1.6	1.1	-0.5	1.4	0.4	1.3	0.3	1.3
Ever taken oral contraceptive pill	0.6	0.6	1.9	0.6	0.8	-0.4	0.6	-0.1	0.7	-0.8	0.4	1.1	0.7	-1.4	0.2	-0.9	-0.8	-1.4	-1.4	-0.3	-0.7	0.9	-0.5	0.1	-1.2	0.3	-1.1	0.4
Hearing aid user	0.8	1.0	2.4	1.1	0.9	-1.4	0.9	-0.3	1.0	1.3	1.1	0.6	1.0	-0.3	-0.6	1.1	0.4	0.2	1.0	1.2	0.2	1.3	1.5	1.3	0.0	1.3	0.6	1.3
Mother’s age at death	0.6	0.7	3.6	0.9	0.7	1.9	0.7	1.6	0.8	0.3	0.5	1.5	0.8	-1.4	-0.6	0.2	-0.2	1.0	-0.2	0.6	0.5	0.7	-1.1	0.5	0.3	-0.2	0.1	0.4
Financial situation satisfaction	0.8	0.9	3.6	-1.1	-1.3	1.9	-1.5	0.1	-1.1	-0.9	-1.3	-1.5	-1.0	-0.9	0.5	-0.9	-0.1	-0.5	-0.5	-1.0	-0.6	-0.7	-0.8	-1.0	-0.7	-0.4	-0.2	-1.0
Tinnitus: Yes, now most or all of the time	0.5	0.5	1.2	0.8	1.1	-0.6	1.1	-0.7	1.0	-0.1	0.6	1.1	0.9	0.2	0.6	-0.2	-0.4	-0.9	-0.7	0.1	-1.1	0.2	-1.0	0.3	-0.9	-0.2	-0.8	0.5
Commuting to job workplace: Public transport	0.2	0.2	0.8	0.6	0.4	-0.9	0.7	-0.2	0.5	0.4	0.1	0.6	0.6	0.9	0.3	0.4	0.5	-0.0	0.1	0.4	-0.5	0.6	-0.2	0.3	0.5	0.3	0.1	0.5
Eye problems/disorders: Glaucoma	0.9	1.1	3.0	-0.0	0.1	-0.7	0.0	-1.4	0.0	-1.3	-0.7	-0.3	-0.1	1.4	0.8	-1.4	-0.9	-1.0	-1.6	-1.0	-1.6	-1.1	-1.5	-0.9	-1.7	-1.1	-1.1	-0.7
Medication: Blood pressure	0.2	0.5	1.5	0.9	1.0	-0.6	0.5	-0.1	1.0	0.2	0.9	1.0	0.9	0.0	-0.1	0.3	0.5	-0.6	-0.4	0.4	-0.0	0.7	0.9	0.5	1.2	-0.9	-0.4	0.7
Pain type(s) experienced in last month: Hip pain	0.4	0.6	3.0	0.7	0.7	0.2	0.7	-0.8	0.7	-0.5	0.2	0.2	0.7	0.5	0.5	-0.6	-1.7	0.4	-1.1	-0.2	-0.4	0.5	-1.6	0.1	-0.1	0.4	-1.4	0.2
Supplements: Fish oil (including cod liver oil)	0.6	0.7	6.5	-0.1	-0.2	2.5	-0.1	1.6	-0.1	-0.3	-0.0	-0.5	-0.1	-1.1	0.0	-0.2	-0.8	0.6	-0.4	-0.2	0.5	-0.8	-2.2	-0.3	0.8	0.2	-0.0	-0.3
High cholesterol (Self-reported)	1.2	2.2	7.9	1.3	1.2	-1.0	1.2	-2.1	1.3	-1.5	0.5	0.9	1.4	0.8	1.5	-1.5	-2.4	-1.2	-2.8	-0.7	-1.8	0.6	-2.1	-0.2	-0.0	-0.9	-2.8	0.2
Medication: Bendroflumethiazide	0.2	0.3	3.9	-0.1	-0.2	-2.0	-0.5	0.3	-0.2	-0.1	-0.1	-0.3	-0.3	0.8	0.0	-0.1	0.7	-1.1	0.0	-0.1	-0.1	-0.7	0.4	-0.3	-0.4	-0.3	0.2	-0.2
Medication: Paracetamol	0.8	1.2	3.2	0.6	0.5	-0.3	0.4	0.7	0.6	1.6	1.0	1.8	0.6	0.0	-1.0	1.7	1.2	1.3	1.6	1.4	1.3	0.6	1.3	1.2	1.3	0.8	1.4	1.0
Medication: Lisinopril	0.5	0.6	4.0	0.4	-0.0	-1.6	0.1	-0.4	0.2	0.5	0.4	1.2	0.5	-0.5	-0.2	0.7	0.9	0.1	0.4	0.4	0.6	1.1	1.8	0.5	2.0	-0.3	0.2	0.4
Medication: Atorvastatin	0.9	1.1	2.4	1.5	1.3	-0.5	1.5	0.2	1.4	1.1	1.3	1.0	1.4	-0.8	-0.8	1.2	1.1	0.3	0.5	1.3	0.6	1.2	1.2	1.4	0.7	0.2	0.2	1.6
Illnesses of father: High blood pressure	0.2	0.2	0.9	0.6	0.4	0.5	0.6	0.4	0.6	0.0	0.4	0.1	0.7	-0.1	-0.1	0.0	-0.6	-0.2	-0.4	0.3	0.4	-0.7	0.1	0.3	0.9	0.0	-0.7	0.2
Alcohol drinker status: Never	1.1	1.3	4.4	-0.4	-0.7	1.0	-0.8	-0.5	-0.5	-1.7	-0.7	-1.2	-0.5	0.2	1.2	-1.6	-0.6	-1.5	-1.9	-1.4	-1.0	-1.3	-1.3	-1.3	-0.8	-1.3	-2.1	-1.0
Ever smoked	0.3	0.5	1.3	1.1	1.0	-0.3	0.9	0.3	1.0	0.5	0.8	0.5	0.8	-0.0	-0.6	0.4	0.4	-0.2	0.0	0.8	-0.1	1.0	0.7	0.9	-1.1	0.0	-0.2	1.0
Basal metabolic rate	0.4	2.0	5.3	-1.8	-1.8	-1.8	-1.8	-1.0	-1.7	-1.3	-1.6	-2.0	-1.4	1.5	2.3	-1.1	-0.5	-1.9	-0.6	-1.7	-1.0	-0.9	-0.3	-1.5	0.4	-0.3	-0.9	-1.5
Leg fat percentage (left)	1.0	3.8	18.2	-0.0	0.0	-3.6	0.1	-4.3	0.0	-1.9	-0.7	-1.4	0.1	2.0	2.4	-1.8	-1.8	-2.1	-2.4	-1.6	-3.5	1.3	0.1	-1.0	-0.9	-2.5	-2.4	-0.7
Arm fat-free mass (left)	0.3	1.4	4.0	-1.2	-1.4	-1.7	-1.4	-1.2	-1.2	-1.2	-1.2	-1.3	-1.0	1.1	2.0	-1.0	-0.5	-1.9	-0.8	-1.4	-1.1	-0.5	-0.0	-1.3	0.4	-0.8	-1.1	-1.2
Number of operations (self-reported)	0.3	0.5	1.8	-0.5	-0.6	-1.3	-0.5	-0.9	-0.6	-1.0	-0.7	-0.2	-0.6	-0.1	0.4	-1.0	-0.3	-0.7	-0.9	-0.9	-0.5	-0.1	0.2	-0.8	-0.6	-0.5	-0.8	-0.6
Average weekly beer plus cider intake	3.0	4.4	10.2	-1.6	-1.6	-1.8	-1.5	-1.7	-1.6	-2.6	-1.9	-2.3	-1.5	2.1	2.2	-2.4	-2.0	-3.2	-2.3	-2.5	-2.1	-2.3	-0.2	-2.3	-0.3	-3.0	-2.6	-2.1
Irritability	0.3	0.4	1.9	-0.6	-0.5	-1.2	-0.8	-1.0	-0.6	0.3	-0.4	-0.5	-0.5	0.9	0.4	0.3	1.0	-0.9	0.8	-0.1	0.1	0.0	1.4	-0.2	-0.4	0.4	0.2	-0.3
Risk taking	1.0	1.4	2.8	1.1	0.8	1.7	0.8	1.2	1.0	1.6	1.3	0.6	1.1	-1.3	-1.1	1.7	0.5	0.1	1.3	1.5	1.0	0.5	1.0	1.5	1.4	1.1	1.4	1.4
Ever had prostate specific antigen (PSA) test	1.9	2.2	6.0	0.8	0.9	-1.1	0.8	1.0	0.8	2.1	1.1	1.6	0.7	-1.2	-1.6	2.0	1.9	1.5	2.2	1.8	1.5	1.4	0.7	1.5	0.2	2.0	2.4	1.4
Fractured/broken bones in last 5 years	0.7	0.9	2.6	-1.6	-1.1	-0.5	-1.6	0.8	-1.3	0.0	-0.8	-0.1	-1.5	1.2	0.3	0.1	1.3	0.9	1.0	-0.7	0.7	-1.2	0.1	-0.7	0.3	-0.3	0.8	-1.0
Age started oral contraceptive pill	2.7	3.4	7.4	1.5	1.5	2.0	1.7	2.7	1.4	1.8	1.6	2.2	1.4	-2.7	-2.6	1.6	1.5	2.3	1.4	2.0	1.9	2.0	-0.0	1.9	-0.3	1.6	2.2	1.6
Diastolic blood pressure, automated reading	0.2	0.6	2.9	-0.3	-0.6	-1.4	-0.5	-1.2	-0.5	0.1	-0.1	-0.2	-0.6	-0.4	-0.3	0.3	1.7	-1.0	0.4	-0.0	-0.5	0.3	1.7	-0.1	-0.6	-1.4	0.1	-0.2
Ever depressed for a whole week	0.4	0.5	2.1	-0.7	-0.9	0.9	-0.9	0.0	-0.8	-0.4	-0.7	-1.2	-0.9	-0.2	0.5	-0.4	0.0	-0.8	0.0	-0.6	-0.6	-0.9	-0.7	-0.7	-1.4	-0.8	-0.3	-0.7
Unable to work because of sickness or disability	2.4	3.1	8.4	0.7	0.7	0.9	0.6	2.6	0.7	2.7	1.4	0.7	0.6	-1.1	-2.1	2.6	2.3	1.8	2.9	2.2	2.1	-0.2	1.3	2.0	0.1	1.7	2.8	1.6
Commuting to job workplace: Cycle	0.2	0.3	1.3	-0.6	-0.5	1.1	-0.5	0.6	-0.6	0.3	-0.2	-0.1	-0.6	0.1	-0.4	0.2	0.6	0.2	0.8	0.1	0.4	-0.9	0.3	-0.1	-0.7	0.5	0.9	-0.3
Myopia	0.6	0.9	3.7	-1.5	-0.9	0.8	-1.4	0.7	-1.2	-0.6	-1.0	-1.9	-1.2	0.4	0.9	-0.5	-0.4	1.1	0.2	-0.8	0.2	-0.5	-1.4	-0.9	0.5	0.7	0.0	-1.0
Vascular/heart problems diagnosed by doctor	0.7	1.8	5.2	-2.3	-1.9	0.7	-1.9	0.1	-2.1	-0.4	-1.7	-1.5	-2.2	1.9	0.4	-0.5	0.1	-0.1	0.9	-1.1	0.4	-2.0	-0.3	-1.5	-1.1	1.0	0.9	-1.7
Cholesterol lowering medication	1.4	2.1	5.2	2.0	2.3	-0.7	1.9	-1.5	2.2	-0.3	1.5	1.9	2.2	-0.1	0.2	-0.5	-1.8	0.5	-1.7	0.4	-1.2	1.8	-2.1	0.9	-0.5	0.1	-1.6	1.1
Medication: Omeprazole (e.g. Zanprol)	0.8	1.0	3.0	-0.2	-0.2	1.2	-0.1	0.5	-0.2	1.1	0.3	-0.3	-0.1	-1.1	-1.0	1.0	1.7	1.7	1.5	0.7	1.3	0.9	1.0	0.6	0.1	1.5	1.7	0.3
Pain experienced in last month	0.3	0.4	1.7	0.5	0.6	0.3	0.7	0.7	0.6	0.8	0.7	0.1	0.6	-1.3	-0.8	0.8	0.9	0.5	0.7	0.8	0.6	0.4	0.1	0.8	0.2	0.4	0.7	0.7
Supplements: Calcium	0.2	0.2	1.6	-0.1	0.1	-0.6	-0.1	-0.2	0.0	-0.1	0.0	-0.2	-0.2	0.1	-0.0	-0.1	0.2	-0.9	-0.1	-0.1	-0.4	-0.9	0.1	-0.1	-1.3	-1.0	-0.3	-0.1
Basal cell carcinoma (self-reported)	0.2	0.3	0.8	-0.4	-0.4	-0.0	0.0	0.4	-0.3	-0.8	-0.6	-0.1	-0.3	-0.4	0.1	-0.8	-0.4	0.1	-0.8	-0.5	-0.1	-0.7	-0.9	-0.7	-0.4	-0.2	-0.3	-0.8
Heart attack/myocardial infarction (self-reported)	1.7	2.2	6.1	2.5	2.1	-0.2	2.2	-0.6	2.3	0.7	1.8	1.8	2.5	-2.0	-0.3	0.6	-0.4	0.2	-0.7	1.2	-0.7	2.4	-0.1	1.7	0.6	-0.0	-0.5	2.0
Deep venous thrombosis (DVT) (self-reported)	0.4	0.5	3.4	-0.1	-0.1	-0.4	-0.0	0.7	-0.1	0.8	0.4	0.4	-0.2	-0.2	-0.9	0.9	1.3	1.8	1.1	0.6	0.8	0.3	0.7	0.5	0.3	0.2	0.9	0.3
Heart disease (siblings)	0.4	0.5	1.6	0.9	0.6	0.4	0.8	0.5	0.8	0.7	0.8	0.7	1.0	-1.3	-0.8	0.7	0.2	-0.4	0.2	0.9	0.2	0.8	1.0	0.9	0.8	-0.1	0.3	0.9
Alcohol drinker status: Previous	0.3	0.3	1.9	-0.4	-0.6	1.4	-0.2	0.7	-0.5	0.3	-0.3	-0.4	-0.4	0.1	-0.3	0.5	0.5	0.3	0.7	0.2	0.3	-0.1	0.8	-0.1	1.0	-0.6	0.4	-0.1
Pack years of smoking	0.2	0.3	1.5	0.4	0.2	-0.8	0.6	-1.0	0.4	0.1	0.1	1.2	0.5	0.7	0.5	0.2	-0.2	0.4	-0.2	0.2	-0.7	0.8	-0.1	0.3	1.1	-0.6	-0.6	0.4
Impedance of whole body	0.0	0.1	0.7	-0.0	0.4	0.0	0.1	0.6	0.1	0.1	0.2	0.3	-0.1	0.1	-0.5	0.1	0.4	0.1	0.1	0.0	-0.0	-0.5	-0.2	0.0	-0.2	-0.8	0.6	0.0
Leg fat mass (left)	1.0	3.9	15.5	-0.8	-0.8	-3.4	-0.8	-3.9	-0.7	-2.0	-1.2	-2.0	-0.6	2.4	2.9	-1.9	-1.6	-2.3	-2.0	-2.0	-3.2	0.5	0.1	-1.4	-0.4	-2.2	-2.2	-1.2
Arm predicted mass (left)	0.3	1.5	4.4	-1.0	-1.3	-1.9	-1.1	-1.4	-1.1	-1.2	-1.1	-1.3	-0.8	1.1	2.1	-1.1	-0.7	-2.0	-1.0	-1.4	-1.3	-0.4	0.1	-1.2	0.5	-0.8	-1.4	-1.1