TWAS hub - MNDA

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0550	0.0220	2.7e-03	0.011	0.008	0.000	0.010	0.004	1.6e-02	3.0e-02	2.8e-01	1.9e-02	9.1e-02
2	GTEx	Whole Blood	0.0920	0.0400	9.3e-03	0.000	NA	0.002	NA	0.005	3.0e-01	NA	2.0e-01	NA	9.9e-02
3	NTR	Blood	0.1987	0.0315	0.0e+00	0.133	0.118	0.127	0.132	0.131	1.4e-40	3.8e-36	1.2e-38	3.1e-40	4.6e-40
4	TCGA	Breast Invasive Carcinoma	0.0476	0.0196	3.1e-07	0.042	0.029	0.032	NA	0.039	5.4e-09	1.2e-06	2.7e-07	NA	1.9e-08
5	TCGA	Cervical Squamous Cell Carcinoma	0.0800	0.0440	8.5e-03	0.005	0.004	0.003	NA	0.003	1.7e-01	2.1e-01	2.2e-01	NA	2.1e-01
6	TCGA	Glioblastoma Multiforme	0.2120	0.0900	6.6e-04	0.025	0.069	0.110	NA	0.070	5.7e-02	3.9e-03	3.2e-04	NA	3.7e-03
7	TCGA	Kidney Renal Clear Cell Carcinoma	0.0565	0.0325	2.1e-03	0.003	0.025	0.027	NA	0.008	1.4e-01	7.2e-04	4.6e-04	NA	3.6e-02
8	TCGA	Brain Lower Grade Glioma	0.1865	0.0563	1.8e-15	0.147	0.155	0.163	NA	0.162	2.2e-16	3.3e-17	4.3e-18	NA	5.5e-18
9	TCGA	Lung Adenocarcinoma	0.0807	0.0361	7.2e-06	0.025	0.026	0.029	NA	0.035	6.3e-04	4.5e-04	2.3e-04	NA	5.1e-05
10	TCGA	Lung Squamous Cell Carcinoma	0.0962	0.0365	8.6e-07	0.062	0.055	0.062	NA	0.056	1.4e-07	7.2e-07	1.5e-07	NA	5.2e-07
11	TCGA	Pancreatic Adenocarcinoma	0.1180	0.0540	2.9e-03	0.021	0.079	0.082	NA	0.058	4.2e-02	3.3e-04	2.5e-04	NA	2.0e-03

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11
Mouth/teeth dental problems: Bleeding gums	4.2	5.5	10.9	-2.2	-1.5	-1.5	-1.9	-2.9	-1.7	-3.3	-2.4	-1.7	-2.4	-3.3
Neuroticism (Nagel 2018)	3.9	9.3	13.8	1.4	3.7	3.7	3.4	3.4	3.4	1.3	3.4	3.4	3.6	-0.5
Alcohol intake versus 10 years previously	3.7	5.5	11.2	-0.2	-0.9	-1.4	-2.5	-3.0	-1.6	-2.5	-3.2	-2.1	-3.4	-2.8
Eye problems/disorders: None of the above	3.5	4.0	7.7	-1.6	-0.7	-1.4	-2.4	-2.2	-1.2	-2.6	-2.8	-2.4	-2.5	0.2
Smoking status: Previous	3.4	5.0	10.0	1.7	2.4	2.2	3.0	1.4	3.0	-0.7	2.5	3.2	2.0	-1.0
Depressed Affect (Nagel 2018)	3.3	6.9	14.5	0.6	3.3	3.5	2.9	2.2	3.8	1.2	2.5	2.9	2.8	0.2
Migraine (self-reported)	3.2	4.0	12.1	1.8	1.2	1.6	0.7	3.5	0.3	3.4	1.7	0.6	1.8	2.6
Headache pain in last month	2.8	4.7	8.3	1.2	2.3	2.5	2.1	2.9	2.3	1.7	2.4	2.1	2.4	1.6
Ever had bowel cancer screening	2.8	3.3	6.5	0.6	0.8	0.9	2.4	0.6	2.1	2.5	2.4	2.4	2.0	1.5
Had other major operations	2.6	3.2	5.7	-0.1	1.0	2.3	2.3	0.8	2.1	2.0	1.8	2.4	1.9	-1.3
Angina (self-reported)	2.6	3.4	4.8	2.0	1.8	1.9	2.1	1.6	1.9	1.4	2.1	2.2	1.8	1.1
Angina	2.5	3.3	5.1	1.8	1.9	1.9	2.1	1.4	2.1	1.5	2.0	2.3	1.7	0.9
Reason for reducing amount of alcohol drunk: Health precaution	2.5	2.9	5.4	0.9	2.1	1.8	1.9	1.6	2.3	0.3	2.0	1.7	2.2	0.4
Number of full sisters	2.5	3.1	6.7	-1.9	-1.1	-1.1	-2.4	-0.5	-1.5	-2.2	-2.2	-2.6	-1.8	0.1
Qualifications: CSEs or equivalent	2.3	3.0	4.1	-1.9	-2.0	-1.9	-1.8	-1.6	-1.4	-1.9	-1.7	-1.7	-2.0	0.6
Commuting to job workplace: Walk	2.3	2.5	5.2	0.0	1.6	1.7	2.3	1.0	1.4	0.2	2.0	2.2	2.2	0.0
Pain type(s) experienced in last month: Hip pain	2.3	3.0	5.9	1.2	2.1	2.4	2.0	1.5	2.1	0.6	1.6	2.1	1.5	-0.2
HbA1C	2.2	2.4	11.1	-3.3	-1.8	-1.8	-0.3	-1.2	-1.5	2.0	-0.3	-0.4	-0.6	0.8
Happiness	2.2	2.7	6.1	1.3	2.2	2.5	1.5	1.8	1.5	1.7	1.1	1.6	1.6	0.4
Eye problems/disorders: Glaucoma	2.2	2.6	6.8	1.3	0.6	1.0	1.6	2.6	0.6	1.4	2.1	1.4	2.2	1.7
Myopia	2.2	3.2	7.6	-0.4	-1.3	-1.7	-2.0	-2.5	-1.5	-1.5	-2.3	-1.9	-2.8	0.1
Time employed in main current job	2.1	2.5	6.9	2.5	2.2	1.7	0.2	2.6	1.6	-1.1	0.7	0.0	1.0	0.8
LDL Cholesterol	2.0	3.2	6.0	1.3	1.7	1.4	1.6	2.4	1.8	1.2	2.2	1.6	2.1	1.9
Serious illness, injury or assault to yourself	2.0	2.4	5.6	0.9	1.7	1.9	1.8	0.8	1.5	2.4	1.4	2.0	1.3	0.3
Medication: Ramipril	2.0	2.6	6.6	2.6	1.7	1.3	0.7	2.5	1.1	2.4	1.4	0.6	1.1	0.8
Length of working week for main job	1.9	2.1	5.4	1.6	1.6	1.6	0.8	2.0	1.2	2.3	0.9	0.9	1.1	1.2
Exposure to tobacco smoke at home	1.9	2.1	4.7	2.1	1.6	1.9	1.4	1.4	2.2	-0.1	1.1	1.4	1.0	-0.1
Illnesses of father: Heart disease	1.9	2.6	6.2	-2.5	-1.7	-1.4	-1.6	-2.1	-1.0	-0.6	-1.8	-1.5	-1.9	-0.6
Medication: Ibuprofen (e.g. Nurofen)	1.8	2.3	6.2	-0.5	0.8	1.0	1.9	-0.1	2.5	2.1	1.7	2.1	1.0	0.7
Mean time to correctly identify matches	1.8	3.4	8.0	-0.5	-1.2	-1.6	-2.4	-1.4	-1.9	-1.7	-2.4	-2.2	-2.8	-0.8
Eye problems/disorders: Cataract	1.8	2.1	4.6	1.4	0.2	0.9	1.7	1.6	0.7	1.8	2.1	1.5	2.0	-0.1
Irritability	1.8	3.0	5.2	0.9	2.2	1.7	2.0	1.8	1.5	1.1	2.3	2.0	1.9	1.2
Worry (Nagel 2018)	1.7	3.7	6.0	1.3	2.5	2.3	1.8	2.3	2.0	1.4	2.0	1.9	2.1	-1.0
Sensitivity / hurt feelings	1.7	3.0	5.4	-0.2	1.9	1.9	2.3	1.5	2.1	-0.4	2.1	2.3	1.9	-0.5
Ever highly irritable/argumentative for 2 days	1.7	2.1	6.4	0.5	0.6	0.9	1.1	2.0	0.8	1.7	1.5	0.8	1.7	2.5
Number of children fathered	1.7	1.9	3.9	1.4	1.8	1.9	1.0	2.0	1.7	0.6	1.1	1.0	1.2	0.1
Medication: Ibuprofen	1.7	2.0	5.3	-0.2	0.5	0.9	1.7	0.0	2.1	2.3	1.6	1.8	1.0	1.4
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.7	2.0	7.7	-2.8	-1.7	-1.6	-0.4	-2.2	-0.6	-0.6	-0.9	-0.4	-1.2	-0.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.7	1.9	5.1	0.4	1.2	1.0	1.6	1.1	1.5	2.2	1.6	1.8	1.2	-0.3
Age at First Birth	1.6	2.4	4.5	-1.1	-1.5	-1.9	-1.6	-1.5	-2.1	-1.8	-1.7	-1.6	-1.1	-0.5
Current tobacco smoking	1.6	2.6	4.9	-1.6	-1.4	-1.2	-2.0	-1.6	-1.6	0.1	-2.1	-1.8	-2.2	-0.1
Irritable Bowel Disease (IBD)	1.5	3.6	5.9	-2.1	-1.2	-1.5	-1.6	-2.4	-1.3	-2.2	-2.3	-1.5	-2.0	-2.0
Reaction Time	1.5	2.9	6.9	-0.4	-0.6	-1.6	-2.3	-1.0	-2.2	-1.4	-2.2	-2.0	-2.6	-0.4
Supplements: Zinc	1.5	1.6	6.1	2.5	1.0	1.1	1.1	1.6	1.0	1.0	1.1	1.2	0.9	0.8
Stomach or abdominal pain in last month	1.5	1.8	5.2	-1.7	-1.5	-2.3	-1.0	-1.0	-1.8	-1.3	-0.4	-1.1	-0.7	-1.1
Past tobacco smoking	1.5	2.8	6.2	-0.5	-1.9	-1.7	-2.1	0.3	-2.5	0.8	-1.1	-2.4	-0.6	2.3
Medication: Lansoprazole	1.5	1.7	4.7	0.9	0.5	1.2	1.3	2.2	0.2	1.6	1.7	1.2	1.8	0.3
Smoking status: Current	1.5	2.3	4.7	-1.7	-1.0	-1.0	-1.9	-1.5	-1.4	-0.1	-2.1	-1.6	-2.2	-0.6
Coronary Artery Disease (CAD)	1.4	1.7	3.5	-1.5	-0.9	-1.0	-1.4	-0.9	-1.4	-0.7	-1.9	-1.4	-1.5	1.3
Blood Eosinophil Count	1.4	10.5	13.8	3.4	3.4	3.7	3.5	3.5	2.9	2.9	3.7	3.6	3.2	0.6
Miserableness	1.4	2.4	4.6	-0.6	1.5	2.1	1.8	1.3	2.0	1.4	1.6	1.8	1.6	0.3
High cholesterol (Self-reported)	1.4	2.4	3.9	1.4	1.7	2.0	1.6	1.8	1.4	1.0	1.5	1.6	1.8	-1.2
Cholesterol lowering medication	1.4	2.0	7.2	1.6	0.7	1.1	1.1	2.7	0.5	0.9	1.9	0.7	2.1	-0.1
Neuroticism	1.3	3.0	5.5	1.0	1.8	1.6	2.2	1.4	2.0	0.7	2.3	2.3	1.8	0.4
Number of treatments/medications taken	1.3	2.4	7.6	1.3	-0.4	0.7	1.7	1.2	0.9	2.8	2.3	1.4	1.9	0.6
Townsend deprivation index at recruitment	1.3	1.8	4.3	-0.5	-0.9	-1.0	-1.1	-1.9	-1.3	-1.6	-2.0	-0.8	-2.1	0.2
Guilty feelings	1.3	1.9	3.2	0.8	1.1	1.4	1.6	1.7	1.4	0.9	1.6	1.6	1.8	0.8
Age started oral contraceptive pill	1.3	1.6	3.5	1.5	0.8	0.6	1.5	1.3	1.0	0.8	1.7	1.4	1.9	0.0
Schizophrenia vs Biploar Disorder	1.2	1.6	3.1	-0.9	-1.2	-1.3	-0.9	-1.3	-0.9	-1.7	-1.2	-0.7	-1.6	-1.7
Crohns Disease (2017)	1.2	2.6	4.4	-1.4	-1.4	-1.9	-1.6	-2.1	-1.6	-1.4	-1.8	-1.6	-2.0	-0.0
Bipolar Disorder (2011)	1.2	1.2	2.5	-1.3	-1.5	-1.1	-1.2	-0.5	-1.6	-0.6	-0.9	-1.2	-0.8	-0.0
Ulcerative Colitis	1.2	1.7	4.1	-2.0	-1.4	-1.4	-1.2	-1.2	-1.0	-0.9	-1.3	-1.3	-0.7	-1.6
Hearing difficulty/problems: Yes	1.2	1.9	5.2	0.3	-0.7	-0.4	-1.4	-1.5	-0.6	-1.5	-1.8	-1.3	-1.8	-2.3
Age when periods started (menarche)	1.2	2.8	6.4	-1.0	-1.4	-1.2	-2.5	-1.1	-0.9	-0.4	-2.3	-2.5	-2.4	-0.5
Nervous feelings	1.2	2.2	6.0	1.0	2.5	1.9	1.6	0.7	2.1	0.8	1.2	1.7	1.1	0.3
Mouth/teeth dental problems: Dentures	1.2	2.1	5.0	0.6	0.8	0.6	2.1	1.8	0.6	-0.0	2.2	2.0	2.1	0.2
Medication: Paracetamol	1.2	1.9	4.0	-0.2	0.5	0.7	2.0	0.9	1.8	1.2	1.9	1.9	1.7	0.7
Medication: Paracetamol	1.2	1.9	3.6	0.4	0.5	0.7	1.6	1.5	1.8	1.3	1.9	1.4	1.5	1.7
Pain experienced in last month	1.2	2.0	3.9	-0.2	-1.3	-1.3	-1.6	-1.6	-1.4	-1.3	-2.0	-1.5	-1.7	0.5
Crohns Disease (2012)	1.1	1.7	2.9	-1.7	-1.2	-1.2	-1.4	-1.4	-0.9	-1.0	-1.3	-1.5	-1.3	-1.3
Taking other prescription medications	1.1	1.7	3.6	-0.2	-0.2	0.4	1.8	0.6	0.2	1.5	1.8	1.7	1.9	-1.7
Ever unenthusiastic/disinterested for a whole week	1.1	1.3	3.4	0.6	1.2	1.1	1.0	0.7	1.7	1.2	0.7	1.0	0.9	1.8
Breastfed as a baby	1.1	1.3	3.2	1.8	0.8	1.2	1.5	0.4	1.5	-0.3	0.8	1.5	0.9	0.7
Exposure to tobacco smoke outside home	1.1	1.5	4.9	2.2	0.5	1.1	0.8	2.2	1.1	0.3	1.4	0.8	1.0	0.4
Number of full brothers	1.1	1.4	5.4	0.6	-0.6	-0.9	-1.4	-0.1	-2.3	-0.1	-1.2	-1.4	-0.8	-1.6
Mood swings	1.1	2.0	3.5	-0.9	1.3	1.5	1.8	0.9	1.9	0.7	1.7	1.9	1.5	0.3
Ulcerative Colitis (UC)	1.0	1.9	6.3	-1.7	-0.7	-0.6	-0.9	-1.7	-0.5	-1.5	-1.7	-0.9	-1.2	-2.5
Bilateral oophorectomy (both ovaries removed)	1.0	1.2	3.7	0.7	0.4	1.4	1.1	1.9	0.4	1.1	1.2	1.1	1.3	0.7
Medication: Levothyroxine sodium	1.0	1.7	5.3	0.5	1.9	2.3	0.4	0.9	2.0	2.0	0.1	0.3	0.8	-0.1
Mouth/teeth dental problems	1.0	1.5	7.1	1.5	-0.0	0.3	-0.2	0.8	0.5	2.7	0.4	-0.2	0.1	2.3
Medication: Simvastatin	1.0	1.5	4.2	0.5	-0.0	0.6	1.6	1.2	0.3	0.9	2.0	1.5	2.0	-0.3
Frequency of tiredness / lethargy in last 2 weeks	1.0	1.7	4.1	-1.8	-1.4	-1.0	-1.1	-2.0	-0.6	0.1	-1.5	-0.9	-1.9	-0.2
Lung cancer (father)	1.0	1.1	6.1	0.7	0.6	0.1	0.6	-0.4	1.4	-2.5	0.2	0.7	0.2	-1.6
Qualifications: NVQ or HND or HNC or equivalent	1.0	1.2	4.2	1.4	1.1	2.0	0.2	1.4	0.9	0.4	0.0	0.2	0.5	-1.6
Depression (Nagel 2018)	0.9	1.4	2.5	0.2	0.7	1.5	1.4	1.0	1.6	1.2	1.1	1.5	1.4	1.0
Hayfever/allergic rhinitis (self-reported)	0.9	1.2	3.1	-0.1	-1.1	-1.0	-1.0	-1.6	-1.8	-0.3	-1.2	-0.7	-1.5	-0.4
Hypothyroidism/myxoedema (self-reported)	0.9	1.7	5.9	-0.0	1.5	2.4	0.8	-0.2	2.4	1.2	-0.1	0.9	0.5	-1.4
Birth weight	0.9	2.0	3.7	-0.9	-1.0	-1.5	-1.9	-0.7	-1.5	-0.3	-1.8	-1.9	-1.8	1.3
Emphysema/chronic bronchitis	0.9	1.0	3.1	-1.8	-1.3	-1.3	-0.6	-0.6	-1.2	-1.1	-0.9	-0.6	-0.7	-0.0
Medication for pain relief, constipation, heartburn	0.9	1.6	3.4	0.0	0.3	-0.4	-1.6	-0.4	-1.7	-1.7	-1.8	-1.5	-1.2	-1.3
Medication: Blood pressure	0.9	1.6	6.9	2.6	1.6	1.0	0.2	2.0	1.2	-0.5	0.8	0.2	0.4	1.1
Had major operations	0.9	1.0	3.5	1.3	0.7	1.3	0.8	0.6	0.6	1.9	0.8	0.9	0.6	0.7
Leg pain on walking	0.9	1.2	2.5	-1.0	0.6	0.8	1.6	0.5	0.9	0.3	1.4	1.4	1.6	-0.9
Loneliness, isolation	0.9	1.2	2.8	-0.7	1.3	1.4	1.1	-0.7	1.7	1.5	0.3	1.6	0.0	-0.5
Alcohol drinker status: Never	0.9	1.1	4.6	0.7	0.6	0.6	0.9	1.3	-0.1	2.2	1.0	1.0	1.1	-0.5
Ever depressed for a whole week	0.9	1.1	4.9	0.9	0.6	0.7	0.8	0.4	1.4	1.1	0.7	0.7	0.7	2.2
Fasting Glucose	0.8	1.0	2.3	1.1	-0.2	-0.7	0.7	1.2	0.8	1.4	1.5	0.5	1.3	0.7
Neuroticism (2016)	0.8	1.1	3.9	0.6	0.6	0.9	1.2	0.4	0.2	2.0	0.8	1.3	1.2	-1.3
Type 2 Diabetes (T2D) (2012)	0.8	1.0	2.8	-1.0	-0.7	-0.0	-1.0	-0.4	-1.7	-1.0	-1.4	-1.1	-0.9	-0.2
Medication: Co-codamol	0.8	0.9	3.2	-0.9	-0.5	-0.2	-0.9	-0.9	-1.0	-1.8	-1.3	-1.0	-0.8	-0.4
Medication: Atenolol	0.8	1.0	3.4	-0.5	0.6	0.4	1.1	1.9	0.0	0.1	1.6	0.9	1.3	0.9
Hearing difficulty/problems with background noise	0.8	1.3	2.9	-0.1	0.7	1.2	1.6	0.7	1.7	0.6	1.3	1.5	1.4	-0.7
Worrier / anxious feelings	0.8	1.5	3.3	-0.2	1.0	1.5	1.7	0.2	1.4	1.3	1.4	1.8	1.1	-0.7
Falls in the last year	0.8	1.0	3.5	-1.5	-1.9	-0.9	-0.3	-1.2	-0.6	-1.2	-0.7	-0.2	-0.7	-0.4
Glaucoma (self-reported)	0.8	0.9	3.2	1.0	-0.4	0.0	0.5	1.8	-0.5	0.7	0.9	0.3	1.1	1.5
Illnesses of siblings: Diabetes	0.8	0.9	2.1	0.5	-0.9	-1.4	-1.0	1.0	-1.4	-0.9	-0.3	-1.4	-0.1	0.5
Ever taken oral contraceptive pill	0.8	0.9	2.0	1.2	1.2	0.8	0.9	1.4	0.8	0.3	1.1	0.8	1.2	0.2
Ever had prostate specific antigen (PSA) test	0.8	1.0	5.1	2.2	1.3	-0.0	-0.6	1.6	-0.1	-0.5	0.1	-0.7	0.2	0.3
Heart disease (siblings)	0.8	1.0	4.5	-0.2	-1.3	-0.7	-0.2	0.8	-1.6	2.1	0.4	-0.4	0.6	0.8
Alzheimer’s Disease (in mother)	0.7	0.8	3.5	-0.7	0.0	0.1	1.1	-0.2	0.4	0.6	0.8	1.1	0.9	-1.9
Verbal and Numeric Reasoning (VNR)	0.7	1.8	9.4	0.8	-1.4	-1.2	-1.1	1.1	-1.2	0.8	-0.1	-1.3	-0.0	3.1
Breast Cancer	0.7	1.8	4.7	1.5	2.1	2.2	0.6	1.0	1.9	1.5	0.2	0.7	0.6	0.5
Ovarian Cancer	0.7	0.9	2.7	1.3	-0.1	-0.6	0.2	1.6	-0.2	-1.0	1.2	-0.0	1.1	1.3
Blood Platelet Count	0.7	8.3	16.4	-2.1	-4.0	-3.7	-2.8	-3.0	-3.2	-1.9	-2.5	-2.7	-3.4	0.4
Smoking Status	0.7	1.6	4.5	0.9	1.5	1.7	1.5	0.3	2.1	0.4	0.9	1.9	0.4	-0.0
Diabetes (mother)	0.7	0.9	3.6	1.8	0.9	0.2	0.1	1.9	0.1	0.4	0.7	-0.1	0.8	0.7
Hayfever, allergic rhinitis or eczema	0.7	1.5	5.4	-1.4	-0.2	1.0	1.2	-1.9	0.8	0.4	-0.0	1.4	0.1	-2.3
Frequency of tenseness / restlessness in last 2 weeks	0.7	1.2	2.8	0.3	0.1	0.7	1.6	0.7	0.7	0.2	1.4	1.7	1.2	1.6
Neuroticism score	0.7	1.5	2.9	-0.6	1.2	1.4	1.6	0.6	1.6	0.9	1.5	1.7	1.2	-0.0
Medication for cholesterol, blood pressure or diabetes	0.7	1.2	3.2	-1.8	-1.2	-0.9	-0.8	-1.7	-0.7	-0.3	-1.4	-0.8	-1.1	-0.6
Chest pain or discomfort	0.7	1.0	3.4	0.0	1.4	1.3	1.0	0.5	1.8	-0.2	0.7	1.1	0.6	-0.9
Medication: Blood pressure	0.7	1.3	3.5	-1.8	-1.9	-1.4	-0.5	-1.0	-1.8	-0.5	-0.4	-0.6	-0.7	-0.2
Medication: Lisinopril	0.7	1.0	2.2	-0.4	-1.3	-1.5	-0.7	-1.2	-1.2	-0.9	-0.5	-0.7	-0.7	0.9
Ever smoked	0.7	1.3	3.8	0.1	1.3	1.5	1.1	-0.3	1.9	0.6	0.3	1.5	-0.1	-1.7
Fractured/broken bones in last 5 years	0.7	0.9	2.5	-0.9	0.7	1.5	0.7	-0.9	0.8	-0.0	-0.3	1.1	-0.2	-1.6
Diastolic blood pressure, automated reading	0.7	2.2	16.0	-0.2	-1.9	-1.2	0.0	0.9	-0.9	1.0	0.8	-0.1	-0.0	4.0
Basal cell carcinoma (self-reported)	0.7	0.8	3.6	1.2	0.6	0.4	0.6	1.1	-0.4	0.1	0.7	0.5	0.9	1.9
Pack years of smoking	0.7	1.1	2.7	0.3	0.9	0.8	0.9	1.6	0.2	1.6	1.3	0.7	1.5	0.4
Mean Putamen Volume	0.6	0.7	1.6	-0.3	-0.8	-0.5	-1.0	-0.4	-0.4	-1.0	-1.2	-0.9	-1.3	0.4
Allergy or Eczema	0.6	1.5	5.8	-1.7	-0.6	0.4	0.5	-2.4	0.2	-0.4	-0.6	0.6	-0.6	-2.4
Average weekly spirits intake	0.6	0.8	4.6	0.0	-1.5	-1.0	0.4	-0.0	-0.4	-0.3	0.6	0.4	0.0	2.1
Medication for hormone replacement therapy	0.6	0.7	3.7	0.5	-0.7	-0.7	0.3	0.9	-0.4	0.8	0.7	0.0	0.9	1.9
Frequency of unenthusiasm / disinterest in last 2 weeks	0.6	0.8	2.3	-0.0	-0.1	0.4	1.3	0.3	0.7	0.4	1.0	1.3	0.8	1.5
Had menopause	0.6	0.7	2.4	-1.3	-0.7	-0.5	0.4	-0.8	0.8	-1.1	-0.1	0.5	-0.6	-1.6
Heart attack	0.6	0.8	1.9	0.7	0.5	0.4	-1.4	0.2	0.3	-1.1	-1.0	-1.3	-1.2	-0.5
Illnesses of siblings	0.6	0.9	2.1	-0.4	0.6	0.2	-0.9	-1.5	0.5	-1.2	-1.4	-0.7	-1.3	-0.5
Qualifications: A levels/AS levels or equivalent	0.6	1.4	3.7	-0.4	-1.4	-0.9	-1.3	-0.8	-0.5	-1.9	-1.1	-1.4	-0.8	1.4
Wheeze or whistling in the chest in last year	0.6	1.0	3.1	-1.4	-1.3	-1.8	-0.4	-0.3	-1.4	-0.8	-0.0	-0.6	-0.5	-0.9
Neck or shoulder pain in last month	0.6	0.8	1.6	0.4	0.2	0.8	1.1	1.0	0.7	1.0	1.3	1.2	1.0	0.4
Family relationship satisfaction	0.6	0.8	2.7	-0.5	1.3	1.3	0.6	-0.2	0.7	1.6	-0.1	0.9	-0.0	0.8
Commuting to job workplace: Car/motor vehicle	0.6	0.7	1.8	1.4	0.4	0.2	-1.1	1.2	0.8	-0.2	-0.5	-1.2	-0.3	0.9
Back pain experienced in last month	0.6	0.8	2.3	-0.3	0.6	0.4	1.3	0.3	1.5	0.3	1.4	1.3	1.0	-0.4
Osteoarthritis (self-reported)	0.6	0.8	2.3	0.8	-1.1	-0.1	0.6	1.5	-0.9	0.5	0.9	0.4	1.0	1.0
Mother’s age at death	0.6	0.8	7.0	0.4	-0.5	-0.7	-0.1	-0.4	-0.5	-0.2	-0.0	-0.0	-0.1	-2.6
Financial situation satisfaction	0.6	0.8	2.1	-1.4	0.3	0.0	-0.4	-1.4	-0.5	0.0	-1.4	-0.2	-1.1	-0.9
Medication: Atorvastatin	0.6	0.7	2.6	1.6	1.2	0.5	0.8	1.0	0.5	-0.3	0.8	0.8	0.5	0.3
Alzheimer’s Disease (in father)	0.5	0.6	3.0	-0.6	-0.6	-0.9	0.7	-0.3	-0.5	-1.7	0.4	0.5	0.9	-0.2
Prostate Cancer	0.5	0.7	2.2	0.6	1.1	0.3	0.2	1.5	0.5	0.3	0.7	0.0	1.0	1.3
Hypothyroidism (self reported)	0.5	1.3	3.7	-1.4	0.4	1.3	0.7	-0.7	1.8	1.1	-0.1	0.9	0.3	-1.9
Respiratory disease	0.5	1.0	3.0	-1.0	-1.7	-1.3	-0.7	-0.2	-1.4	-1.3	-0.3	-0.7	-0.5	-0.8
Medication: Metformin	0.5	0.7	2.9	-0.1	-0.3	-0.5	-0.6	-0.7	-0.3	-1.7	-0.8	-0.5	-1.4	0.4
Fed-up feelings	0.5	1.0	2.5	-1.4	0.5	0.4	1.2	0.1	0.9	0.4	1.0	1.2	1.0	1.6
Tinnitus: Yes, but not now, but have in the past	0.5	0.5	2.6	-0.8	0.7	0.3	0.7	-0.9	0.2	-0.3	0.3	0.9	0.2	-1.6
Diverticular disease/diverticulitis (self-reported)	0.5	0.5	1.5	-0.8	-0.7	-1.2	-0.5	-1.0	-0.5	-0.3	-0.4	-0.6	-0.3	-1.0
Number of incorrect matches in round	0.5	0.9	1.9	-1.4	-0.6	-1.1	1.2	-1.0	0.5	0.4	1.2	1.2	0.6	0.6
Hair/balding pattern: Pattern 2	0.5	0.7	2.6	-0.2	-0.2	-0.5	-0.9	1.3	-0.9	1.6	0.1	-1.2	0.4	0.2
Medication: Cholesterol lowering	0.5	0.7	1.8	0.8	0.7	0.6	1.1	0.7	0.6	0.6	1.4	1.1	1.1	0.3
Pulse wave reflection index	0.5	0.6	1.7	-0.5	0.6	0.8	0.5	-1.3	1.0	-0.0	-0.3	0.9	-0.7	-0.9
Gout (self-reported)	0.5	0.6	2.2	1.5	0.8	0.9	0.4	0.5	0.7	1.4	0.4	0.5	0.2	0.1
Medication: Amlodipine	0.5	0.7	1.3	-1.1	-0.9	-1.0	-0.1	-1.1	-0.3	-1.1	-0.3	-0.1	-1.0	1.0
Medication: Ventolin 100micrograms inhaler	0.5	0.6	2.1	1.2	0.2	0.5	0.4	1.5	-0.4	0.0	1.0	0.2	1.1	0.6
Seen a psychiatrist for nerves, anxiety, tension or depression	0.5	0.6	3.4	-0.2	-1.3	-0.8	-0.1	0.2	0.4	1.0	0.3	-0.2	0.2	1.9
Medication: Omeprazole	0.5	0.6	2.2	-0.6	-1.5	-0.9	0.1	-1.3	-0.6	0.6	-0.1	-0.0	0.0	-0.7
Arm predicted mass (right)	0.5	2.6	4.9	-0.4	-1.6	-1.9	-2.2	-0.4	-1.9	0.3	-1.6	-2.2	-2.1	1.1
Supplements: Vitamin C	0.5	0.6	2.7	1.6	1.0	0.9	-0.4	0.1	0.1	-0.9	-0.8	-0.2	-0.8	-0.2
Average weekly red wine intake	0.5	0.7	2.9	-1.3	-1.7	-1.2	0.3	-1.0	-0.4	-0.4	0.4	0.1	0.0	-0.5
Friendships satisfaction	0.5	0.6	2.2	-0.1	0.9	0.9	0.5	0.1	1.1	1.5	0.3	0.6	0.4	0.8
Qualifications: nursing, teaching	0.5	0.8	2.4	1.1	0.8	0.7	0.4	0.8	1.0	1.0	0.7	0.5	0.5	1.6
Medication: Gliclazide	0.5	0.6	3.5	0.1	0.1	0.2	0.9	0.2	-0.2	-1.9	0.5	1.0	-0.1	0.9
Illnesses of father: None of the above (group 1)	0.5	0.6	1.8	1.4	1.1	1.2	0.3	0.9	0.7	0.5	0.4	0.3	0.6	0.2
Wears glasses or contact lenses	0.5	0.6	2.1	1.5	-0.3	0.6	0.6	0.9	-0.2	1.1	0.7	0.5	0.8	0.5
Hearing aid user	0.5	0.6	1.8	-0.0	-0.1	-0.3	-0.8	-1.2	-0.3	-0.8	-1.1	-0.6	-1.4	-0.8
Medication: Omeprazole (e.g. Zanprol)	0.5	0.7	1.6	-1.0	-1.3	-0.6	0.5	-1.3	-0.2	1.1	0.2	0.4	0.4	-0.9
Heart attack/myocardial infarction (self-reported)	0.5	0.6	1.5	0.5	0.4	0.2	-1.2	0.2	0.4	-1.1	-0.8	-1.2	-1.1	-0.5
Body Mass Index (BMI) (2010)	0.4	0.5	2.3	-0.2	-0.7	-0.6	-0.7	-0.6	-0.2	-0.1	-0.7	-0.7	-0.9	1.5
Schizophrenia (2014)	0.4	0.9	2.9	-1.7	-1.5	-0.9	-0.0	-0.9	-1.3	0.2	-0.3	-0.0	-0.4	-0.8
Blood Red Count	0.4	4.1	35.4	6.0	-0.3	-0.7	-1.0	1.0	-1.2	1.0	-0.1	-1.2	-0.6	1.8
Waist Hip Ratio (WHR)	0.4	1.7	9.1	3.0	1.2	0.8	0.2	1.9	0.1	1.2	0.7	0.0	1.1	0.3
Cardiovascular Disease	0.4	1.3	3.2	0.9	-0.1	0.9	1.1	1.8	0.2	0.7	1.6	1.0	1.4	1.3
Frequency of depressed mood in last 2 weeks	0.4	0.6	2.4	-0.8	0.1	0.9	0.8	0.3	0.5	0.7	0.4	0.9	0.4	1.6
Systolic blood pressure, automated reading	0.4	1.3	5.4	-0.5	-2.1	-1.4	-0.5	0.4	-1.1	-0.2	0.3	-0.6	-0.3	2.3
Diabetes (father)	0.4	0.4	1.2	-0.1	-0.1	-0.1	-0.5	-0.9	0.0	-0.9	-0.8	-0.2	-1.1	-1.0
Severe depression (siblings)	0.4	0.4	0.8	-0.7	-0.9	-0.7	-0.4	-0.5	-0.6	-0.7	-0.4	-0.5	-0.8	0.7
Pack years adult smoking proportion	0.4	0.6	2.4	0.2	0.6	0.5	0.4	1.6	-0.1	1.1	0.8	0.3	1.0	0.6
Leg fat-free mass (left)	0.4	2.3	5.4	0.7	-1.1	-1.4	-2.3	-0.2	-1.4	0.6	-1.4	-2.3	-1.9	1.6
Average weekly fortified wine intake	0.4	0.4	0.8	0.7	-0.9	-0.7	-0.4	0.7	-0.4	-0.7	-0.2	-0.4	-0.5	0.9
Maternal smoking around birth	0.4	0.6	2.5	1.1	1.6	1.2	-0.0	0.6	0.7	-0.5	-0.3	0.0	0.0	0.0
Chronic bronchitis/emphysema (father)	0.4	0.5	3.0	-0.8	-0.3	-0.0	0.0	-0.6	-0.6	1.7	-0.4	0.1	0.1	-0.8
High blood pressure (mother)	0.4	0.5	2.2	0.5	0.3	0.8	0.2	1.0	-0.1	1.5	0.2	0.2	0.4	1.1
Leg predicted mass (left)	0.4	2.1	5.1	0.7	-1.1	-1.4	-2.2	-0.1	-1.4	0.7	-1.3	-2.2	-1.9	1.6
Waist circumference	0.4	1.3	4.9	2.2	-0.3	-0.6	-1.0	1.7	-0.8	0.3	0.2	-1.3	0.2	1.7
Forced vital capacity (FVC)	0.4	1.5	4.0	-0.4	0.3	-0.3	-1.6	-1.5	-0.2	-1.1	-2.0	-1.5	-1.9	0.4
Qualifications: None of the above	0.4	0.8	2.5	1.4	1.6	0.3	-0.8	1.4	0.6	0.6	-0.3	-0.8	-0.4	0.3
Allergy	0.4	1.0	5.6	1.0	0.7	-0.6	-0.7	1.3	-0.2	0.2	0.3	-0.8	0.1	2.4
Weight	0.4	1.7	3.8	1.4	-1.0	-1.3	-1.8	0.6	-1.2	0.5	-0.7	-1.9	-1.1	1.9
Trunk fat-free mass	0.4	2.1	4.6	-0.0	-1.6	-1.6	-2.1	-0.4	-1.4	0.6	-1.4	-2.1	-1.8	1.1
Forced expiratory volume in 1-second (FEV1)	0.4	1.5	3.4	-0.6	-0.2	-0.8	-1.6	-1.7	-0.4	-0.6	-1.8	-1.6	-1.8	0.3
Forced expiratory volume in 1-second (FEV1), Best measure	0.4	1.1	3.0	0.3	0.6	0.1	-1.7	-0.4	-0.3	-0.0	-1.7	-1.6	-1.6	0.8
Qualifications: O levels/GCSEs or equivalent	0.4	0.6	2.6	-0.6	-1.6	-0.3	-0.2	-1.3	-1.1	-0.5	-0.4	-0.0	-0.5	0.7
Chronic bronchitis/emphysema (mother)	0.4	0.5	1.4	-0.3	-0.7	-1.0	-0.3	-0.5	-0.8	-1.2	-0.4	-0.3	-0.5	-0.9
High blood pressure (siblings)	0.4	0.6	1.9	0.6	0.2	0.6	0.5	0.8	0.9	0.9	0.7	0.4	0.4	1.4
Forced vital capacity (FVC), Best measure	0.4	1.5	3.8	0.6	1.2	0.6	-1.9	-0.2	0.2	-0.1	-1.9	-1.9	-1.7	0.7
Arm fat-free mass (right)	0.4	2.0	4.2	-0.1	-1.4	-1.6	-2.0	-0.4	-1.5	0.3	-1.4	-2.0	-2.0	1.1
Health satisfaction	0.4	0.5	3.2	-0.7	0.5	0.2	0.6	-0.1	0.4	1.8	0.4	0.7	0.4	-0.3
Suffer from ‘nerves’	0.4	0.6	2.8	0.8	0.9	0.8	-0.1	1.7	0.9	0.7	0.4	-0.1	0.3	0.7
Forced expiratory volume in 1-second (FEV1), predicted	0.4	0.8	2.9	0.7	0.9	0.6	-1.0	1.3	0.3	0.4	-0.3	-1.2	-0.3	1.7
Leg fat-free mass (right)	0.4	1.9	4.1	0.5	-1.1	-1.4	-2.0	-0.4	-1.4	0.5	-1.3	-2.0	-1.9	1.3
Mouth/teeth dental problems: Mouth ulcers	0.4	0.6	2.5	-0.5	0.2	-0.4	-0.3	-0.6	-0.1	-1.6	-0.5	-0.4	-0.4	-1.6
Medication for cholesterol	0.4	0.6	1.7	0.0	1.3	0.6	-0.5	-0.8	1.0	-0.7	-1.0	-0.3	-1.1	-0.4
Number of self-reported non-cancer illnesses	0.4	0.7	2.0	1.4	-0.4	0.7	1.1	0.6	0.1	0.8	1.1	1.1	0.9	-0.4
Average weekly champagne plus white wine intake	0.4	0.5	1.7	-0.5	0.3	0.7	0.9	-0.0	0.8	0.3	0.7	0.8	0.6	-1.3
Basal metabolic rate	0.4	1.9	4.5	0.5	-1.2	-1.4	-2.1	-0.1	-1.4	0.7	-1.3	-2.1	-1.7	1.5
Unable to work because of sickness or disability	0.4	0.5	2.3	0.8	1.5	1.0	-0.6	0.5	0.7	0.3	-0.6	-0.3	-0.5	-0.2
Supplements: Calcium	0.4	0.5	1.7	-1.3	-0.3	-0.2	0.9	-0.1	0.1	-0.5	0.6	0.9	0.7	-0.8
Intelligence (Savage-Jansen 2018)	0.3	1.0	4.3	0.9	-1.1	-0.5	-1.1	0.9	-0.6	0.2	-0.6	-1.3	-0.7	2.1
Schizophrenia (2018)	0.3	0.5	2.0	-0.8	-1.4	-0.9	0.2	-0.7	-1.1	0.6	-0.1	0.2	-0.3	-0.6
Rheumatoid Arthritis	0.3	0.4	1.3	-0.3	-0.7	-0.5	0.6	0.5	0.5	-0.2	1.0	0.4	0.7	1.1
Triglycerides	0.3	0.5	1.1	0.6	0.5	0.9	0.6	0.3	0.8	0.5	0.7	0.7	1.0	0.7
Blood White Count	0.3	2.5	9.2	2.2	3.0	2.3	-0.0	1.1	2.2	0.8	-0.3	0.5	-0.7	0.7
Chronotype (morning person)	0.3	0.7	1.7	-1.1	1.0	0.5	1.0	-0.5	1.3	-0.5	0.6	1.0	0.7	0.1
Relative age of first facial hair	0.3	0.6	1.4	-0.9	-0.3	-0.7	-0.7	-0.7	-0.8	-1.2	-1.0	-0.6	-1.1	0.0
Other serious medical condition/disability diagnosed by doctor	0.3	0.4	1.2	-1.1	-0.7	0.1	0.5	-0.1	-0.8	0.8	0.3	0.5	0.7	0.5
Ever used hormone-replacement therapy (HRT)	0.3	0.3	1.0	-0.2	0.4	1.0	0.8	0.5	0.6	0.1	0.3	1.0	0.2	-0.3
Ever had hysterectomy (womb removed)	0.3	0.3	1.1	-0.2	0.5	1.0	0.4	0.9	0.3	-0.5	0.2	0.5	0.3	0.6
Impedance of leg (right)	0.3	1.4	2.5	0.3	1.6	1.5	1.1	1.2	1.2	-0.9	0.8	1.1	1.5	-0.9
Multivitamins +/- minerals	0.3	0.4	1.0	1.0	0.1	0.9	0.6	0.7	0.4	0.5	0.8	0.6	0.7	-0.5
Impedance of leg (left)	0.3	1.7	2.6	-0.0	1.5	1.6	1.5	0.9	1.3	-1.1	0.8	1.6	1.4	-1.6
Alcohol usually taken with meals	0.3	0.4	4.0	0.3	-0.1	-0.1	-0.3	-0.2	-0.0	-0.4	-0.3	-0.5	-0.0	-2.0
Diabetes (self-reported)	0.3	0.4	1.4	0.8	0.7	-0.0	0.5	0.5	-0.0	-1.0	0.5	0.6	0.2	-1.2
Impedance of arm (right)	0.3	1.6	4.0	1.5	2.0	1.8	0.8	0.7	1.7	-0.8	0.5	0.8	1.0	-0.9
Hair/balding pattern: Pattern 3	0.3	0.5	2.1	0.2	-0.7	-0.3	0.9	-1.5	-0.0	-0.4	0.3	0.9	0.1	-0.6
Number of live births	0.3	0.4	0.7	-0.3	-0.8	-0.9	-0.4	0.8	-0.7	-0.5	0.3	-0.7	0.4	0.8
Pulse rate	0.3	0.4	1.6	-0.4	-0.7	-0.8	-0.4	0.8	-0.8	-1.3	0.1	-0.6	0.1	0.5
Asthma	0.3	0.6	2.7	-0.5	-1.6	-1.3	-0.0	0.2	-1.4	-0.5	0.3	-0.1	0.0	-0.3
Depression (self-reported)	0.3	0.3	2.6	-0.4	-0.5	-0.1	0.0	0.4	0.3	0.2	0.2	-0.0	0.4	1.6
Prospective memory result	0.3	0.3	0.9	0.5	0.0	-0.2	-0.5	0.3	0.3	-0.9	-0.3	-0.5	-0.7	1.0
Illnesses of mother	0.3	0.3	1.8	-0.0	-0.0	0.2	0.4	-0.9	0.1	-0.5	-0.1	0.5	-0.5	1.3
Trunk predicted mass	0.3	1.9	4.2	-0.1	-1.5	-1.5	-2.0	-0.3	-1.3	0.6	-1.4	-2.1	-1.8	0.9
Birth weight of first child	0.3	0.5	2.6	0.3	-0.0	-0.4	-0.4	-0.5	-0.7	0.9	-0.4	-0.4	-0.2	-1.6
Peak expiratory flow (PEF)	0.3	0.8	2.1	-1.0	-0.5	-0.8	-0.8	-1.4	-0.5	-0.4	-1.0	-0.8	-0.9	-1.2
Leg fat percentage (right)	0.3	0.9	3.7	1.9	0.1	-0.3	-0.4	1.6	-0.1	0.7	0.6	-0.5	0.5	1.6
Comparative body size at age 10	0.3	0.8	1.8	0.7	-0.7	-0.2	1.3	0.1	-0.1	0.5	1.3	1.2	1.0	1.2
Medication: Allopurinol	0.3	0.4	2.0	0.8	0.1	0.2	-0.0	-0.7	0.1	0.9	-0.2	0.1	-0.5	-1.4
Medication: Seretide 50 evohaler	0.3	0.3	1.5	0.6	0.4	0.6	-0.5	1.2	-0.1	0.6	-0.4	-0.6	-0.1	0.5
Heart disease (mother)	0.3	0.4	1.8	-0.5	0.3	0.4	0.2	-0.6	1.3	0.5	0.3	0.0	0.8	-0.9
Illness, injury, bereavement, stress in last 2 years	0.3	0.3	1.9	0.8	1.4	0.7	-0.0	0.5	0.0	0.2	0.1	-0.1	0.4	-0.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.3	0.3	0.6	0.6	-0.7	-0.1	0.8	-0.4	0.3	0.1	0.7	0.8	0.1	0.8
Whole body fat-free mass	0.3	1.9	4.2	0.2	-1.3	-1.4	-2.0	-0.3	-1.3	0.6	-1.4	-2.0	-1.9	1.2
Handedness (chirality/laterality): Left-handed	0.3	0.4	0.9	-0.9	-0.2	-0.5	-0.6	-0.7	-0.5	-0.7	-0.6	-0.6	-0.7	0.0
Asthma (self-reported)	0.3	0.5	2.2	-0.3	-1.5	-1.0	0.4	0.5	-1.1	-0.2	0.7	0.3	0.4	-0.3
Osteoporosis (self-reported)	0.3	0.4	1.5	-0.9	0.1	0.5	0.4	-0.4	0.5	1.2	0.3	0.4	0.1	-1.0
Whole body water mass	0.3	2.0	4.3	0.2	-1.4	-1.4	-2.1	-0.3	-1.4	0.7	-1.4	-2.1	-1.9	1.2
Leg predicted mass (right)	0.3	1.8	3.9	0.5	-1.1	-1.3	-2.0	-0.5	-1.3	0.5	-1.3	-2.0	-1.9	1.2
Tinnitus: Yes, now most or all of the time	0.3	0.3	2.2	0.9	0.0	-0.2	-0.1	0.6	-0.0	0.2	0.3	-0.3	0.2	1.5
Supplements: Fish oil (including cod liver oil)	0.3	0.5	1.9	1.1	-0.0	0.8	0.4	0.4	0.5	0.3	0.4	0.3	0.7	1.4
Illnesses of father: High blood pressure	0.3	0.4	1.4	-0.0	-0.3	0.0	0.2	1.1	-0.5	0.8	0.6	0.2	0.6	1.2
Arm fat-free mass (left)	0.3	1.6	3.3	0.0	-1.3	-1.4	-1.8	-0.0	-1.3	0.5	-1.1	-1.8	-1.6	1.4
Average weekly beer plus cider intake	0.3	0.4	1.2	0.8	0.7	0.8	0.3	-0.6	0.0	1.1	-0.3	0.6	-0.5	0.4
Commuting to job workplace: Cycle	0.3	0.4	1.2	-1.1	0.3	0.6	1.0	-0.1	0.1	-0.5	0.6	1.1	0.3	0.2
Impedance of whole body	0.3	1.6	3.1	0.8	1.7	1.8	1.1	0.7	1.5	-1.4	0.5	1.1	1.1	-1.3
Arm predicted mass (left)	0.3	1.6	3.2	-0.0	-1.2	-1.4	-1.8	-0.2	-1.2	0.6	-1.2	-1.8	-1.7	1.1
Bipolar Disorder or Schizophrenia	0.2	0.5	1.5	-1.2	-1.0	-0.7	0.4	-0.6	-1.2	0.4	0.1	0.4	0.2	-0.7
Alzheimer’s Disease (including proxy)	0.2	0.3	1.2	-0.3	-0.1	-0.7	0.6	-0.0	-0.5	0.1	0.6	0.5	0.9	-1.1
HDL Cholesterol	0.2	0.4	1.0	-0.9	0.5	0.1	-0.3	-0.6	0.3	-1.0	-0.6	-0.3	-0.6	-1.0
BMI	0.2	1.3	3.9	0.9	-1.5	-1.9	-0.5	0.6	-1.4	0.6	0.7	-0.7	-0.0	2.0
Systolic Blood Pressure	0.2	0.9	3.4	-0.7	-1.3	-0.6	-0.7	0.6	-1.1	1.1	-0.1	-0.6	-0.6	1.9
Type 2 Diabetes (T2D) (2018)	0.2	0.4	2.7	0.4	0.6	-0.1	0.1	1.6	-0.5	-0.6	0.7	0.0	0.6	-0.2
Lung FVC	0.2	1.1	3.7	1.3	1.9	1.4	-0.5	0.9	1.2	0.6	-0.8	-0.4	-0.3	1.2
Eye problems/disorders: Diabetes related eye disease	0.2	0.3	0.9	-0.9	0.5	0.2	0.2	-0.7	0.4	-0.4	-0.2	0.3	-0.4	-0.7
Trunk fat percentage	0.2	0.7	5.0	2.2	0.4	-0.0	-0.5	0.9	0.0	-0.0	0.1	-0.6	-0.1	0.7
Hand grip strength (right)	0.2	0.4	2.1	0.8	-0.8	-0.7	0.3	0.2	0.0	0.3	0.7	0.3	0.1	1.4
Relative age voice broke	0.2	0.3	1.3	-0.4	0.2	0.3	-0.2	0.7	-0.5	1.2	-0.4	-0.2	0.1	0.5
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.4	3.1	-0.1	-0.4	-0.3	0.3	-0.4	0.1	1.8	0.4	0.3	0.5	0.6
Sitting height	0.2	1.2	2.7	0.4	-0.8	-1.1	-1.6	-0.8	-0.6	-0.2	-1.2	-1.6	-1.6	0.9
Body mass index (BMI)	0.2	0.9	2.2	1.2	-0.8	-1.1	-1.1	0.8	-0.9	0.9	-0.1	-1.2	-0.3	1.5
Trunk fat mass	0.2	0.8	4.4	2.1	-0.1	-0.5	-1.1	0.8	-0.4	0.2	-0.2	-1.2	-0.6	1.0
Financial difficulties in last 2 years	0.2	0.2	0.5	0.6	0.2	0.7	0.3	0.2	0.7	0.7	0.2	0.4	0.3	-0.6
Fluid intelligence score	0.2	0.5	2.2	0.4	-0.3	-0.2	-0.8	0.8	-0.7	0.4	-0.4	-0.8	-0.5	1.5
Arm fat percentage (right)	0.2	0.8	4.6	2.1	0.3	-0.1	-0.2	1.3	-0.0	0.7	0.6	-0.5	0.6	1.1
Hip circumference	0.2	0.8	2.9	0.6	-1.0	-1.0	-0.9	0.6	-0.6	0.7	0.0	-1.1	-0.4	1.7
Noisy workplace	0.2	0.3	1.3	0.5	-1.1	-0.9	0.1	0.6	0.0	-0.1	0.6	-0.1	0.2	-0.0
Serious illness, injury or assault of a close relative in last 2 years	0.2	0.2	1.0	-0.9	-1.0	-0.0	-0.2	-0.5	-0.1	0.2	-0.3	-0.2	0.0	0.1
Pulse wave Arterial Stiffness index	0.2	0.2	0.7	0.6	0.0	-0.1	0.7	-0.0	0.4	-0.6	0.7	0.8	0.1	0.2
Impedance of arm (left)	0.2	1.1	2.3	1.3	1.5	1.4	0.4	0.1	1.3	-1.5	-0.1	0.5	0.3	-1.1
Arm fat mass (right)	0.2	0.8	2.0	1.4	-0.6	-0.9	-1.0	0.7	-0.7	0.6	-0.1	-1.2	-0.4	1.3
Loud music exposure frequency	0.2	0.2	1.0	0.0	-0.2	0.0	-0.0	1.0	-0.3	0.5	0.4	-0.2	0.6	-0.0
Blood clot in the leg (DVT)	0.2	0.2	0.9	0.1	0.2	1.0	-0.2	0.4	-0.4	0.9	-0.5	0.1	-0.3	-0.4
Body fat percentage	0.2	0.8	5.2	2.3	0.3	-0.1	-0.4	1.3	-0.1	0.2	0.4	-0.5	0.3	1.1
Age at first live birth	0.2	0.3	0.8	-0.1	0.7	0.2	0.8	-0.1	0.8	-0.1	0.6	0.9	0.5	-0.6
Pulse wave peak to peak time	0.2	0.3	0.9	-0.4	-0.2	-0.0	-0.8	0.1	-0.5	0.4	-0.8	-1.0	-0.2	-0.2
Whole body fat mass	0.2	0.8	3.2	1.8	-0.4	-0.8	-1.0	0.8	-0.7	0.3	-0.1	-1.1	-0.5	1.1
Leg fat mass (right)	0.2	0.8	2.3	1.4	-0.5	-0.9	-1.0	1.0	-0.6	0.3	-0.0	-1.1	-0.3	1.5
Pulse rate, automated reading	0.2	0.7	2.4	-0.0	-0.8	-0.8	-0.3	-0.3	-1.1	-1.2	-0.5	-0.2	-0.5	1.6
Alcohol intake frequency.	0.2	0.6	1.5	-0.3	-0.3	-0.2	-1.1	-0.5	-1.0	0.4	-1.2	-0.9	-0.8	-0.6
Arm fat percentage (left)	0.2	0.8	4.6	2.1	0.1	-0.3	-0.5	1.1	-0.2	0.5	0.4	-0.7	0.2	1.1
Long-standing illness, disability or infirmity	0.2	0.3	2.3	-0.2	-0.7	-0.6	-0.4	-0.2	-1.5	0.3	-0.0	-0.3	-0.0	-0.3
Diabetes diagnosed by doctor	0.2	0.3	1.0	1.0	0.6	0.1	0.3	1.0	-0.1	-0.6	0.5	0.4	0.2	-0.7
Ever had stillbirth, spontaneous miscarriage or termination	0.2	0.2	1.3	-0.7	-0.3	0.2	0.4	0.1	-0.2	-1.1	0.2	0.4	0.2	0.6
Mineral and other dietary supplements	0.2	0.3	0.7	-0.7	0.4	-0.1	-0.8	0.3	-0.3	-0.1	-0.7	-0.8	-0.5	-0.4
Breast cancer (self-reported)	0.2	0.2	0.9	0.1	-0.3	0.3	-0.0	0.6	0.7	0.9	0.0	-0.0	-0.4	0.3
Medication: Aspirin	0.2	0.2	0.6	0.4	-0.8	-0.8	-0.3	0.4	0.0	-0.4	0.2	-0.4	-0.3	0.7
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.2	0.5	2.2	0.4	0.4	0.5	-0.8	0.0	0.1	0.3	-0.8	-0.8	-0.6	1.5
Arm fat mass (left)	0.2	0.9	3.1	1.7	-0.3	-0.6	-1.1	0.9	-0.7	0.7	-0.2	-1.2	-0.4	1.2
Commuting to job workplace: Public transport	0.2	0.2	1.7	-0.5	-0.1	0.2	0.4	-0.1	0.1	1.3	0.4	0.4	0.3	-0.1
Medication: Bendroflumethiazide	0.2	0.2	0.9	0.8	-0.9	0.2	-0.1	0.2	-0.1	-0.3	0.1	-0.0	-0.3	1.0
Leg fat percentage (left)	0.2	0.6	2.8	1.7	0.0	-0.4	-0.2	1.2	-0.0	0.5	0.5	-0.3	0.3	1.0
Number of operations (self-reported)	0.2	0.3	1.2	0.7	-0.2	0.9	0.1	1.1	0.3	0.6	0.3	0.2	0.5	-0.5
Risk taking	0.2	0.3	1.4	-0.8	-1.2	-0.4	0.3	-0.4	-0.7	-0.4	0.1	0.3	0.2	-0.5
Deep venous thrombosis (DVT) (self-reported)	0.2	0.3	0.7	-0.1	-0.4	0.4	-0.6	0.0	-0.9	0.6	-0.8	-0.4	-0.6	-0.6
Alcohol drinker status: Previous	0.2	0.2	0.9	-0.1	-0.2	0.2	-0.4	-0.5	-0.2	0.0	-0.7	-0.4	-0.1	-1.0
Leg fat mass (left)	0.2	0.7	1.5	1.2	-0.6	-1.0	-0.9	0.7	-0.7	0.2	-0.1	-1.0	-0.5	1.2
Bipolar Disorder (2018)	0.1	0.2	0.9	-1.0	0.2	0.1	0.4	-0.1	-0.6	-0.0	0.3	0.4	0.6	-0.4
Major Depression (MDD)	0.1	0.1	0.5	-0.2	0.7	0.1	0.1	-0.5	0.7	-0.2	-0.4	0.2	-0.3	-0.0
Lupus	0.1	0.2	0.6	-0.8	-0.3	0.1	0.5	-0.5	0.2	-0.4	0.0	0.6	0.2	-0.1
Primary Biliary Cirrhosis	0.1	0.2	0.8	0.9	0.3	-0.1	-0.0	0.7	-0.5	-0.2	0.2	-0.1	0.4	0.1
Height	0.1	1.3	2.7	-0.5	-1.2	-1.2	-1.1	-1.5	-0.6	-1.5	-1.3	-1.1	-1.6	-0.2
Lung FEV1/FVC ratio	0.1	0.4	1.3	-1.0	-0.7	-0.7	-0.2	-1.1	-0.4	-0.0	-0.4	-0.3	-0.4	-0.6
Hand grip strength (left)	0.1	0.3	1.2	0.3	-0.6	-1.0	0.0	-0.1	-0.1	-0.2	0.5	-0.1	0.2	1.1
Vitamin and mineral supplements	0.1	0.2	0.8	-0.9	0.5	-0.1	0.0	-0.3	0.6	0.1	-0.1	-0.0	-0.0	-0.2
High blood pressure	0.1	0.3	1.9	0.5	-0.3	0.4	-0.0	0.8	-0.2	-0.7	0.3	-0.1	-0.2	1.4
Supplements: Glucosamine	0.1	0.2	1.0	-0.1	-0.4	-0.2	0.3	-1.0	0.3	-0.1	0.1	0.3	-0.1	0.2
Heel bone mineral density (BMD) T-score, automated (right)	0.1	0.2	0.7	0.1	0.0	-0.0	0.5	-0.5	0.4	0.7	0.3	0.7	0.3	0.9
Pain all over the body in last month	0.1	0.1	0.3	-0.6	-0.0	-0.2	-0.0	-0.3	-0.4	-0.6	-0.1	-0.0	-0.2	-0.2
Father’s age at death	0.1	0.2	0.6	-0.2	-0.4	0.2	0.5	-0.2	0.0	-0.8	0.3	0.4	0.4	-0.5
Standing height	0.1	1.3	3.3	0.2	-0.8	-0.6	-1.7	-0.7	-0.6	-0.8	-1.6	-1.8	-1.8	0.6
Tense / ‘highly strung’	0.1	0.2	0.4	-0.6	-0.5	0.1	0.6	-0.0	0.4	0.2	0.6	0.5	0.5	-0.2
Seen doctor (GP) for nerves, anxiety, tension or depression	0.1	0.1	0.7	-0.7	-0.0	0.1	0.1	0.3	0.9	-0.0	0.3	0.1	0.2	-0.3
Hair/balding pattern: Pattern 4	0.1	0.2	0.9	-1.0	-0.3	-0.4	-0.4	-0.3	-0.2	-0.5	-0.6	-0.4	-0.3	0.1
Worry too long after embarrassment	0.1	0.2	0.7	-0.4	-0.2	-0.1	0.2	0.9	-0.1	0.0	0.5	0.0	0.6	-0.2
Shortness of breath walking on level ground	0.1	0.1	0.7	-0.1	-0.1	-0.4	-0.3	-0.2	0.0	0.8	-0.0	-0.3	-0.1	-0.6
Qualifications: College or University degree	0.1	0.3	0.7	0.6	-0.7	-0.2	0.0	0.6	0.1	0.8	0.5	-0.3	0.6	0.7
Mouth/teeth dental problems: Loose teeth	0.1	0.2	0.8	-0.6	0.3	0.3	0.1	-0.1	0.5	-0.9	-0.1	0.1	-0.0	-0.0
Comparative height size at age 10	0.1	0.4	1.7	0.9	-0.1	0.2	-0.7	-0.0	0.1	-1.3	-0.5	-0.7	-0.7	-0.5
Overall health rating	0.1	0.2	0.5	-0.5	0.5	0.2	-0.3	-0.7	0.3	0.5	-0.5	-0.1	-0.7	0.5
Age at last live birth	0.1	0.2	0.4	0.2	0.1	-0.5	0.4	-0.2	0.6	0.2	0.5	0.3	0.6	0.3
Medication: Aspirin	0.1	0.2	0.5	0.7	-0.3	-0.3	-0.3	0.3	0.5	-0.5	0.0	-0.3	-0.5	0.1
Knee pain experienced in last month	0.1	0.2	0.8	-0.9	0.3	0.4	0.3	-0.4	0.7	0.3	-0.1	0.3	-0.1	0.2
Hypertension (Self-reported)	0.1	0.4	1.5	0.9	-0.4	0.3	-0.1	0.7	-0.3	-0.7	0.3	-0.2	-0.1	1.2
Vascular/heart problems diagnosed by doctor	0.1	0.3	1.8	-0.2	0.7	-0.2	-0.0	-0.3	0.3	0.5	-0.2	-0.1	0.5	-1.3
Heel T-Score	0.0	0.3	0.7	-0.2	-0.6	-0.6	0.6	-0.3	-0.2	0.0	0.8	0.6	0.5	0.8
Hair Pigment	0.0	1.2	2.6	-1.4	0.1	0.4	-0.7	-1.5	0.1	-1.4	-1.6	-0.8	-1.2	-1.5
Tanning	0.0	0.4	2.8	-0.3	0.1	-0.3	-0.4	0.2	0.1	0.9	-0.1	-0.3	0.3	1.7

Hub : Genes

MNDA

Models

Trait associations