Hub : Genes

MOXD1

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.0930 0.0320 2.1e-03 0.033 0.030 0.026 0.039 0.025 6.0e-05 1.3e-04 3.4e-04 1.3e-05 4.9e-04
2 GTEx Cells Transformed fibroblasts 0.1520 0.0560 3.4e-03 0.072 NA 0.080 NA 0.080 4.2e-06 NA 1.4e-06 NA 1.4e-06
3 GTEx Esophagus Muscularis 0.2180 0.0830 5.2e-03 0.079 NA 0.139 NA 0.148 1.6e-05 NA 8.6e-09 NA 2.8e-09
4 GTEx Ovary 0.5690 0.1150 5.3e-04 -0.006 NA 0.026 NA 0.055 4.7e-01 NA 7.8e-02 NA 1.8e-02
5 GTEx Skin Sun Exposed Lower leg 0.1360 0.0500 4.9e-03 0.067 NA 0.067 NA 0.062 3.4e-06 NA 3.2e-06 NA 7.2e-06
6 GTEx Thyroid 0.1470 0.0480 8.4e-04 0.090 NA 0.064 NA 0.066 2.2e-07 NA 1.2e-05 NA 9.5e-06
7 TCGA Breast Invasive Carcinoma 0.0463 0.0227 1.5e-03 0.011 0.012 0.008 NA 0.005 1.8e-03 1.1e-03 8.5e-03 NA 3.2e-02
8 TCGA Thyroid Carcinoma 0.1400 0.0440 6.5e-08 0.064 0.097 0.116 NA 0.103 7.9e-07 1.0e-09 2.3e-11 NA 3.1e-10

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bipolar Disorder (2018) 0.7 1.1 2.6 -0.7 0.4 0.0 -0.8 1.6 1.2 1.6 0.9
Bipolar Disorder or Schizophrenia 0.9 2.3 7.8 -1.5 0.7 0.3 -1.1 2.2 -0.0 2.8 1.3
Depressed Affect (Nagel 2018) 1.2 2.5 6.2 1.7 -2.5 0.9 0.9 -2.1 0.4 -2.1 -0.4
Depression (Nagel 2018) 1.5 2.3 6.1 1.0 -1.6 0.2 -0.1 -2.5 1.6 -2.1 1.3
Intelligence (Savage-Jansen 2018) 0.1 0.3 0.8 0.3 0.4 -0.4 0.9 0.7 -0.3 -0.2 0.7
Neuroticism (Nagel 2018) 0.9 2.2 6.4 1.2 -2.1 0.2 0.6 -2.2 0.1 -2.5 0.6
Schizophrenia (2018) 0.8 1.6 5.4 -1.3 0.5 0.4 -1.0 1.6 -1.0 2.3 0.9
Schizophrenia vs Biploar Disorder 0.9 1.2 5.4 1.0 0.0 1.0 -1.2 -0.6 -2.3 -0.0 0.6
Worry (Nagel 2018) 0.3 0.6 2.1 0.1 -0.6 -0.3 0.8 -0.7 -0.0 -1.5 1.1
Alzheimer’s Disease (in mother) 0.5 0.6 1.1 1.0 -1.1 0.7 0.2 -1.0 -0.6 -1.0 0.2
Alzheimer’s Disease (in father) 0.6 0.7 2.9 -0.2 -0.0 1.7 0.8 -0.0 -0.7 -0.7 1.0
Alzheimer’s Disease (including proxy) 0.6 0.9 3.6 0.8 -0.6 1.9 0.3 -0.7 -1.0 -0.7 0.5
Crohns Disease (2017) 0.4 0.8 2.3 0.6 -1.1 0.6 -1.5 -0.6 0.2 -1.4 -0.4
Irritable Bowel Disease (IBD) 0.5 1.1 2.0 0.6 -1.1 1.1 -1.3 -0.8 -0.2 -1.4 -1.3
Ulcerative Colitis (UC) 0.3 0.6 1.8 0.6 -0.3 1.1 -1.2 -0.2 -0.1 -0.5 -1.3
Major Depression (MDD) 0.8 1.0 2.2 0.3 -1.5 1.1 -0.5 -1.0 1.0 -1.1 -0.9
Reaction Time 0.3 0.6 2.6 -1.6 0.7 0.1 0.1 0.6 0.6 1.0 0.3
Verbal and Numeric Reasoning (VNR) 0.3 0.6 1.5 -0.4 0.6 -1.1 1.0 0.9 -0.1 -0.4 1.2
Breast Cancer 0.6 1.4 3.2 -1.1 -1.2 -0.4 1.6 -0.8 1.4 -0.2 1.8
Ovarian Cancer 0.4 0.5 1.3 0.1 -1.1 -0.8 1.2 -0.5 0.2 0.6 -0.3
Prostate Cancer 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
Age at First Birth 0.8 1.2 2.7 -1.6 1.6 0.2 0.9 1.0 -0.8 1.1 0.6
Bipolar Disorder (2011) 1.3 1.3 4.3 -1.6 0.7 2.1 -0.5 0.7 0.7 0.7 1.1
Body Mass Index (BMI) (2010) 0.3 0.4 0.8 0.8 -0.6 -0.5 0.3 -0.8 0.5 -0.2 0.9
Coronary Artery Disease (CAD) 0.5 0.5 1.4 -0.6 -1.2 0.6 0.3 -1.0 0.9 -0.5 0.3
Crohns Disease (2012) 0.2 0.4 1.0 -0.5 0.1 -0.3 -0.5 1.0 0.7 -0.3 0.9
Mean Putamen Volume 1.0 1.1 2.8 0.5 -0.7 -1.6 1.7 -0.3 -0.5 -0.4 1.5
Fasting Glucose 0.4 0.5 1.3 -0.0 -0.2 -1.1 0.7 -0.6 0.6 -1.2 0.0
HbA1C 0.1 0.1 0.4 0.3 -0.2 -0.3 0.3 0.3 -0.3 -0.6 -0.1
HDL Cholesterol 0.8 1.3 7.9 0.8 -0.0 -0.1 -2.8 -0.5 -1.0 -0.7 0.1
LDL Cholesterol 1.0 1.6 7.9 -1.2 0.8 0.1 2.8 1.1 -1.3 0.1 -0.1
Lupus 0.6 0.9 4.1 -1.2 -0.2 -0.0 -0.4 0.4 2.0 -0.2 1.0
Neuroticism (2016) 0.2 0.3 0.7 -0.6 0.4 0.7 0.1 0.2 -0.4 0.0 0.8
Primary Biliary Cirrhosis 0.9 1.3 3.7 1.9 -1.4 0.6 0.8 -1.4 -0.2 -1.3 -0.5
Rheumatoid Arthritis 0.7 1.0 3.8 0.4 -0.8 -0.6 1.4 0.3 0.3 0.8 -2.0
Schizophrenia (2014) 0.7 1.6 4.9 -1.5 0.2 0.6 -1.1 1.2 -0.6 2.2 1.6
Triglycerides 1.2 1.9 11.0 -0.4 -0.2 -1.0 3.3 0.4 0.4 -0.2 -1.7
Type 2 Diabetes (T2D) (2012) 1.3 1.5 6.1 1.2 -0.6 2.5 -0.5 -0.6 0.4 -0.8 1.6
Ulcerative Colitis 0.3 0.5 1.9 -0.1 -0.1 0.9 -1.0 0.3 -0.1 0.3 -1.4
Blood Eosinophil Count 0.1 1.0 5.8 0.5 -0.1 -0.3 -2.4 -0.3 0.1 -0.9 0.8
Blood Platelet Count 0.1 0.8 2.8 0.4 -0.6 1.1 -1.7 -0.8 0.2 -0.9 0.5
Blood Red Count 0.1 0.8 3.8 -0.4 0.0 -1.9 -0.0 -0.4 -0.6 0.0 -1.5
Blood White Count 0.1 0.6 1.4 0.5 -0.9 0.4 -1.1 -0.5 0.7 0.0 1.2
Heel T-Score 0.4 2.8 7.7 0.6 -1.1 -2.2 0.9 0.6 2.8 2.1 -1.8
BMI 0.1 0.6 2.4 0.3 -0.2 -0.7 -1.5 -0.1 0.7 -0.7 0.7
Height 1.1 21.5 51.6 -4.0 -2.1 -7.2 6.1 -2.5 5.0 -3.7 4.2
Waist Hip Ratio (WHR) 1.5 6.9 17.8 -4.2 1.9 -0.6 0.5 1.9 3.5 1.1 4.0
Systolic Blood Pressure 0.2 0.8 2.5 -1.1 1.6 0.5 -0.1 1.2 -0.7 -0.4 -0.6
Smoking Status 0.1 0.3 1.0 0.1 -1.0 -0.4 0.4 -0.2 -0.1 0.9 0.2
Allergy or Eczema 0.6 1.5 7.5 -0.3 0.2 -1.2 2.7 1.0 0.1 0.5 -1.4
Cardiovascular Disease 0.2 0.7 2.4 0.2 -0.4 -1.2 0.4 -0.5 -0.3 -1.5 -0.9
Hypothyroidism (self reported) 0.3 0.7 1.8 0.6 -0.5 0.5 -0.7 -1.1 -0.7 -0.7 -1.4
Respiratory disease 0.7 1.5 4.3 2.1 -1.3 -0.1 1.9 -0.6 0.8 0.3 -1.3
Type 2 Diabetes (T2D) (2018) 0.7 1.4 3.9 1.5 -1.2 0.5 -0.1 -1.3 -0.1 -1.4 -2.0
Lung FEV1/FVC ratio 0.3 1.8 3.7 -1.6 -0.9 -1.9 1.3 -0.8 1.8 -0.5 1.1
Lung FVC 0.7 3.7 9.1 -0.8 2.5 2.4 -3.0 1.8 -1.0 1.6 0.9
Neuroticism 0.6 1.4 3.5 0.8 -1.2 1.4 -0.2 -1.4 -0.1 -1.9 1.4
Chronotype (morning person) 0.4 1.0 4.2 -2.1 -0.2 0.3 -0.3 0.1 0.0 0.1 1.9
Hair Pigment 0.0 1.4 4.7 -0.4 0.8 -1.1 1.0 0.3 -2.2 0.6 -1.6
Tanning 0.1 1.1 3.6 -0.9 1.3 1.2 -0.2 1.1 -0.2 1.9 0.5
Hand grip strength (left) 0.9 2.5 10.1 -0.9 -0.4 0.5 0.6 -0.4 2.8 -0.3 3.2
Number of treatments/medications taken 1.0 1.8 3.7 1.9 -1.1 -0.2 0.7 -0.9 1.9 -1.4 -1.4
Average weekly spirits intake 1.0 1.2 2.5 -1.6 1.4 -0.7 -0.1 0.8 -0.8 1.0 1.6
Sensitivity / hurt feelings 0.9 1.6 8.2 1.2 -0.8 0.8 -0.2 -1.1 -0.5 -2.9 0.2
Frequency of depressed mood in last 2 weeks 0.8 1.1 3.0 -1.1 -0.1 1.4 0.3 -0.8 1.0 -0.9 1.7
Hearing difficulty/problems: Yes 0.4 0.7 3.6 1.9 -0.5 -0.6 -0.4 -0.5 0.4 -0.8 -0.3
Relative age of first facial hair 0.4 0.8 3.6 0.0 -0.2 1.1 0.2 -0.4 1.2 0.0 1.9
Other serious medical condition/disability diagnosed by doctor 0.9 1.2 3.6 0.5 1.9 1.2 -0.0 1.7 -0.1 0.9 -0.5
Ever used hormone-replacement therapy (HRT) 0.4 0.5 1.0 1.0 -0.9 -0.3 -0.2 -0.9 0.2 -0.3 -1.0
Ever had hysterectomy (womb removed) 1.0 1.1 5.2 1.3 0.6 -0.1 0.2 0.4 -1.2 0.0 -2.3
Systolic blood pressure, automated reading 0.1 0.3 0.9 0.3 0.2 -0.7 -0.7 0.4 -0.1 -0.9 -0.7
Eye problems/disorders: Diabetes related eye disease 0.5 0.5 2.3 0.3 -0.2 -0.1 0.1 0.1 0.4 1.5 -1.3
Angina 1.3 1.7 3.0 1.7 -1.3 1.5 -1.7 -1.6 0.3 -0.9 0.7
Medication for hormone replacement therapy 0.8 0.9 3.6 -0.2 0.1 1.9 0.4 0.2 0.6 1.7 -0.5
Vitamin and mineral supplements 0.6 0.8 1.8 -0.9 0.6 0.3 -0.7 1.0 0.2 1.4 1.4
Supplements: Zinc 0.4 0.4 1.3 -0.3 1.1 0.5 -0.3 0.4 -0.7 0.2 -0.8
Medication: Co-codamol 4.1 4.7 13.3 2.5 -2.9 1.1 -1.9 -3.6 0.4 -2.2 -0.6
Medication: Metformin 0.4 0.5 1.9 -0.5 -0.6 -0.8 0.5 -0.6 0.8 -0.2 -1.4
Diabetes (father) 0.9 1.1 2.5 -0.5 1.3 1.6 -0.8 1.3 -0.5 1.4 -0.3
Diabetes (mother) 1.4 1.8 6.9 0.9 -0.9 0.5 -1.9 -1.4 -0.3 -2.6 0.3
Severe depression (siblings) 0.5 0.6 1.5 -1.0 0.6 1.2 0.0 0.1 0.6 0.4 1.2
Pack years adult smoking proportion 0.9 1.3 4.5 0.7 -0.2 1.6 -0.5 0.8 0.2 1.5 -2.1
Impedance of leg (right) 0.4 1.9 4.3 -1.4 1.3 1.6 -0.6 2.0 0.3 2.1 0.7
Leg fat-free mass (left) 0.9 4.6 14.2 -0.3 -2.0 -3.8 1.2 -2.5 1.7 -2.7 0.8
Trunk fat percentage 0.2 0.9 4.4 -0.6 -0.3 -2.1 -1.3 0.0 0.9 -0.2 0.3
Hand grip strength (right) 0.9 2.4 8.4 -1.5 -0.5 0.8 1.8 -0.3 2.1 -0.4 2.9
Townsend deprivation index at recruitment 0.2 0.3 1.0 0.1 -1.0 0.1 0.8 -0.6 0.4 0.1 -0.5
Current tobacco smoking 0.6 0.9 2.2 0.0 -1.5 -0.3 0.9 -0.6 1.5 1.2 0.3
Average weekly fortified wine intake 2.8 3.3 6.9 2.6 -2.0 1.3 -1.5 -1.8 -0.9 -0.9 -2.6
Maternal smoking around birth 0.8 1.2 3.5 0.0 0.7 1.9 1.2 1.1 0.6 1.6 -0.3
Fed-up feelings 0.3 0.6 2.4 0.1 -0.7 0.7 0.3 -0.7 0.4 -1.5 0.8
Frequency of unenthusiasm / disinterest in last 2 weeks 1.2 1.5 3.3 0.4 -1.3 0.4 0.4 -1.7 1.8 -1.2 1.6
Relative age voice broke 1.1 1.7 4.5 -0.5 0.0 1.4 -0.8 -0.9 1.9 -1.3 2.1
Taking other prescription medications 1.0 1.5 4.1 2.0 -0.7 1.3 -0.2 -0.7 1.3 -1.1 -1.7
Age when periods started (menarche) 1.5 3.5 10.4 -2.3 1.0 -3.2 1.0 1.0 1.4 -1.5 2.3
Bilateral oophorectomy (both ovaries removed) 1.2 1.4 3.1 1.6 0.2 -0.6 -0.4 -0.5 -1.5 -1.6 -1.8
Heel bone mineral density (BMD) T-score, automated (left) 0.6 1.5 5.2 -0.8 1.0 -0.1 0.7 1.8 1.0 2.3 0.5
Tinnitus: Yes, but not now, but have in the past 1.0 1.1 4.0 0.2 -1.3 -0.3 0.1 -1.5 2.0 -0.7 0.2
Qualifications: CSEs or equivalent 0.9 1.1 3.6 0.3 -1.2 -0.7 -0.3 -1.8 -0.0 -1.9 -0.2
Serious illness, injury or assault to yourself 0.5 0.6 1.5 1.2 0.7 1.2 -0.8 0.5 0.0 -0.6 -0.3
High blood pressure 0.5 1.3 3.4 0.5 -1.0 -1.8 0.9 -1.0 0.4 -1.8 -0.7
Hayfever, allergic rhinitis or eczema 0.4 0.8 3.0 -0.6 0.5 -0.7 1.7 1.2 0.5 0.9 -0.4
Multivitamins +/- minerals 0.1 0.2 0.7 -0.1 0.2 0.2 0.7 -0.3 -0.3 -0.8 -0.2
Stomach or abdominal pain in last month 3.3 4.2 9.1 2.6 -2.4 0.1 -0.7 -2.7 2.0 -3.0 0.4
Supplements: Glucosamine 0.9 1.1 2.4 -0.6 1.2 -0.6 1.3 1.5 1.5 0.3 -0.3
Diverticular disease/diverticulitis (self-reported) 1.0 1.1 3.5 1.1 -1.4 -0.3 -0.2 -1.1 1.9 -1.0 -0.3
Medication: Atenolol 1.2 1.5 3.0 -0.1 -1.4 -0.6 -0.6 -1.5 1.7 -1.6 1.1
Medication: Levothyroxine sodium 0.3 0.4 2.0 0.6 0.3 0.4 -0.2 0.3 -0.1 -0.9 -1.4
Sitting height 0.9 6.4 20.1 0.9 -2.7 -2.6 1.1 -3.6 1.1 -4.5 1.0
Chronic bronchitis/emphysema (father) 0.9 1.0 1.9 1.3 -0.8 -0.6 -1.3 -1.0 -1.0 -1.4 -0.3
High blood pressure (mother) 0.8 1.1 4.7 1.0 0.3 -0.6 -1.2 -0.5 -0.9 -2.2 -0.6
Body mass index (BMI) 0.3 1.3 3.3 0.8 -1.4 -1.8 -1.3 -1.2 0.5 -0.7 -0.4
Impedance of leg (left) 0.5 2.2 5.0 -1.9 1.4 1.2 0.0 2.1 0.6 2.2 0.8
Leg predicted mass (left) 0.9 4.7 14.0 -0.3 -2.1 -3.7 1.3 -2.4 1.8 -2.8 0.8
Trunk fat mass 0.4 1.9 9.7 -0.7 -0.9 -3.1 -0.5 -0.7 1.4 -1.0 0.6
Waist circumference 0.7 2.7 7.3 -0.6 -1.5 -2.7 -0.2 -1.5 2.3 -1.5 1.3
Number of incorrect matches in round 0.7 1.2 2.9 -0.1 -0.8 -1.7 0.1 -0.8 1.7 0.3 1.5
Past tobacco smoking 0.5 1.0 3.2 -1.1 -0.1 -1.0 0.6 -0.0 1.8 -1.1 1.0
Alcohol usually taken with meals 1.0 1.7 2.9 -1.3 1.0 -0.8 1.7 1.6 1.0 1.3 1.4
Nervous feelings 0.5 1.0 2.9 0.3 -0.4 0.6 1.7 -0.9 -1.0 -1.4 0.4
Frequency of tenseness / restlessness in last 2 weeks 1.5 2.3 8.1 0.2 -1.3 -0.5 -0.0 -2.4 1.2 -2.9 1.2
Hearing difficulty/problems with background noise 0.6 0.9 2.0 1.2 -0.5 -0.8 1.4 -1.1 -0.6 -0.9 -0.7
Hair/balding pattern: Pattern 2 0.8 1.1 3.8 -0.4 1.6 -0.5 0.0 2.0 -0.1 1.2 0.2
Had menopause 1.1 1.4 4.5 2.1 -0.5 1.0 -1.4 -0.4 -0.0 0.3 -1.8
Had other major operations 2.1 2.5 8.9 3.0 -1.6 0.7 -1.0 -1.4 0.1 -1.6 -1.7
Forced vital capacity (FVC) 0.6 2.4 6.3 -2.3 1.4 -0.7 1.4 1.1 1.4 -0.1 2.5
Heel bone mineral density (BMD) T-score, automated (right) 0.4 1.0 3.0 -0.0 -0.2 -0.9 1.5 1.1 1.7 0.6 0.8
Ever unenthusiastic/disinterested for a whole week 0.9 1.1 4.4 -1.2 0.4 2.1 0.5 -0.0 -0.5 -1.5 -0.1
Qualifications: None of the above 0.7 1.4 3.5 0.7 -1.7 -0.0 -0.9 -1.9 0.2 -1.8 -0.4
Financial difficulties in last 2 years 0.7 0.9 3.4 0.1 0.5 0.5 -1.8 0.0 0.9 -0.3 1.5
Mouth/teeth dental problems 2.4 3.7 10.1 -3.2 2.7 0.1 1.2 2.7 -0.5 1.5 1.0
Heart attack 0.6 0.7 1.5 0.1 -1.2 -0.4 0.9 -1.1 0.2 -1.1 0.8
Allergy 0.4 1.0 3.2 -1.2 0.3 0.5 -1.8 -0.2 -0.2 -0.5 1.5
Pain all over the body in last month 0.9 1.0 3.5 -0.7 -0.7 -0.5 0.1 0.5 1.3 1.9 -1.1
Diabetes (self-reported) 0.6 0.9 6.5 0.3 -0.6 0.3 0.3 -0.4 -0.3 -0.1 -2.5
Hayfever/allergic rhinitis (self-reported) 0.2 0.3 0.9 0.7 -0.1 -1.0 0.2 -0.4 -0.2 -0.7 0.4
Medication: Ramipril 0.6 0.7 2.8 0.0 0.7 1.4 -1.7 0.5 -0.0 -0.0 -0.3
Medication: Simvastatin 0.4 0.6 4.3 0.1 0.1 -0.2 -0.1 0.1 -0.2 -0.8 -2.1
Fluid intelligence score 0.2 0.5 1.8 -0.5 0.2 -1.3 -0.0 -0.2 -0.2 -0.7 1.2
Illnesses of siblings 0.5 0.7 2.4 0.0 0.5 1.0 -0.2 0.3 -1.1 1.6 -0.8
Neuroticism score 0.5 1.1 4.3 0.1 -0.7 0.7 1.2 -0.6 0.6 -2.1 1.2
Weight 0.9 4.4 14.8 -0.3 -2.3 -3.9 0.5 -2.3 2.0 -2.2 0.8
Impedance of arm (right) 0.3 1.4 2.7 -1.0 1.4 1.0 1.2 1.6 -1.3 0.9 -0.8
Arm fat percentage (right) 0.2 0.7 2.1 0.5 -0.8 -1.4 -1.3 -0.6 -0.1 -0.3 -0.7
Trunk fat-free mass 1.3 7.6 17.2 -0.3 -3.0 -4.2 2.0 -3.4 2.7 -3.0 1.5
Hip circumference 1.3 5.5 12.5 1.6 -3.5 -2.9 -0.0 -3.5 1.3 -2.5 -0.8
Time employed in main current job 0.8 1.0 4.0 0.7 0.2 2.0 -1.4 0.0 0.6 0.9 -0.2
Alcohol intake versus 10 years previously 1.3 1.9 5.0 0.4 -1.4 -0.9 -1.3 -1.8 2.2 -1.4 0.6
Father’s age at death 1.1 1.5 9.9 0.1 0.9 -0.5 -0.7 0.4 -3.1 -0.6 -0.5
Worrier / anxious feelings 0.5 1.0 3.0 0.8 -0.9 -0.1 -0.1 -1.4 0.1 -1.7 1.3
Frequency of tiredness / lethargy in last 2 weeks 1.1 1.7 3.4 1.2 -1.4 1.2 1.0 -1.6 1.1 -1.8 0.6
Falls in the last year 0.4 0.5 2.0 -0.2 0.9 0.9 -0.2 0.6 0.1 1.4 0.3
Hair/balding pattern: Pattern 3 0.5 0.8 3.6 0.6 -1.1 0.0 0.7 -0.6 0.1 0.1 -1.9
Number of live births 0.5 0.8 2.4 0.6 -0.3 -1.5 0.7 -0.7 0.9 -1.1 0.4
Forced expiratory volume in 1-second (FEV1) 0.7 2.5 6.2 -2.5 1.2 -1.1 1.8 0.7 1.5 -0.1 2.3
Pulse rate 1.0 1.7 4.2 1.2 -1.2 -0.6 -2.0 -1.6 0.6 -1.4 -1.0
Happiness 1.4 1.7 7.2 -1.6 -0.1 2.7 -0.4 -0.8 -0.9 -0.8 1.2
Noisy workplace 0.8 1.0 3.7 0.0 -0.4 -1.3 -0.1 -1.5 -0.2 -1.9 0.1
Qualifications: A levels/AS levels or equivalent 0.9 1.9 5.3 -0.7 1.8 0.8 -0.7 2.0 -1.1 2.3 -0.5
Serious illness, injury or assault of a close relative in last 2 years 2.5 2.9 6.6 1.2 -2.5 -2.6 0.5 -2.1 1.3 -1.3 0.9
Mouth/teeth dental problems: Dentures 3.7 6.2 20.6 4.5 -3.1 -0.0 -1.1 -3.0 0.3 -2.4 -1.7
Asthma 0.8 1.6 4.6 2.0 -1.0 0.3 2.2 -0.2 0.4 0.8 -1.4
Medication: Ibuprofen (e.g. Nurofen) 0.1 0.1 0.5 -0.1 0.2 0.7 0.3 0.1 0.1 0.1 0.6
Medication: Cholesterol lowering 0.4 0.6 2.0 -0.7 1.4 -0.2 -0.2 1.1 0.4 -0.5 0.6
Depression (self-reported) 0.4 0.5 1.0 0.6 -0.3 -0.4 0.7 -0.4 -0.8 -1.0 0.9
Medication: Lansoprazole 1.1 1.2 2.6 1.5 -1.6 0.3 0.6 -0.8 1.2 0.2 -1.6
Prospective memory result 0.5 0.6 2.6 0.7 0.6 0.1 -0.0 0.1 -1.0 0.8 -1.6
Lung cancer (father) 0.7 0.8 2.3 0.2 -1.4 0.6 1.0 -1.0 1.5 0.1 0.1
Illnesses of mother 0.3 0.4 1.1 0.5 -0.7 -0.0 1.0 -1.1 0.3 -0.0 0.1
Forced expiratory volume in 1-second (FEV1), Best measure 0.8 2.6 7.1 -2.3 1.0 -1.0 1.5 0.7 2.0 0.1 2.7
Pulse wave Arterial Stiffness index 1.2 1.5 5.4 2.3 -0.2 0.7 -1.3 -1.0 -0.7 -1.1 -1.1
Impedance of arm (left) 0.4 2.0 4.6 -1.7 2.1 0.9 1.0 2.1 -0.4 1.3 0.3
Arm fat mass (right) 0.4 1.8 7.1 0.1 -1.6 -2.7 -0.7 -1.3 1.0 -1.1 0.1
Trunk predicted mass 1.3 7.7 16.8 -0.5 -3.0 -4.1 2.1 -3.4 2.8 -3.1 1.6
Standing height 1.1 10.8 21.3 -2.9 -1.8 -4.6 4.0 -2.2 3.7 -3.3 3.0
Length of working week for main job 1.0 1.1 3.1 -1.6 -0.7 -0.3 0.9 -0.0 0.8 1.1 1.8
Exposure to tobacco smoke at home 1.3 1.5 4.2 0.5 -1.2 -0.5 -1.2 -1.7 -1.1 -2.1 -0.4
Breastfed as a baby 0.8 1.0 3.5 0.6 0.5 0.6 -0.7 -0.3 -1.7 -1.9 0.3
Tense / ‘highly strung’ 0.3 0.5 1.8 -0.6 -0.3 -0.6 -0.0 -0.6 0.0 -1.3 1.1
Seen doctor (GP) for nerves, anxiety, tension or depression 0.5 0.7 2.5 0.1 -0.7 -0.9 1.6 -0.8 0.9 -0.7 0.3
Hair/balding pattern: Pattern 4 0.5 1.3 6.9 -1.0 -0.2 0.9 -0.3 0.1 2.6 0.1 1.3
Birth weight of first child 0.9 1.6 3.8 1.4 -1.8 -0.2 0.0 -1.7 0.8 -1.9 0.7
Peak expiratory flow (PEF) 0.4 1.0 3.1 -1.5 1.0 0.9 1.8 0.4 -0.2 -0.0 1.0
Pulse wave reflection index 0.6 0.7 1.5 1.0 0.8 -0.0 -0.5 0.6 -1.2 1.2 -0.6
Ever highly irritable/argumentative for 2 days 0.8 0.9 3.2 -0.8 0.3 0.5 -0.5 -0.4 1.3 -1.0 1.8
Loud music exposure frequency 2.0 2.1 7.9 -0.5 1.2 2.0 -2.8 -0.2 -1.8 0.1 0.0
Qualifications: O levels/GCSEs or equivalent 1.0 1.5 3.8 -0.9 1.5 1.1 -0.1 1.8 -0.9 1.9 -0.1
Mouth/teeth dental problems: Bleeding gums 0.8 1.0 1.9 1.3 -1.1 -0.8 -1.3 -1.4 0.7 -0.8 0.0
Blood clot in the leg (DVT) 1.3 1.7 3.5 1.3 -0.9 -0.0 1.9 -1.3 0.9 -1.8 -1.4
Medication: Paracetamol 0.2 0.4 1.1 1.0 -0.5 0.2 0.3 -0.8 0.1 -0.9 0.4
Headache pain in last month 0.9 1.5 3.9 -1.8 -1.0 -0.3 2.0 -0.7 1.0 -0.2 1.5
Medication for cholesterol, blood pressure or diabetes 0.3 0.5 1.1 0.5 -1.0 0.9 -0.2 -1.0 -0.9 0.4 -0.2
Glaucoma (self-reported) 0.7 0.8 3.2 -0.4 0.1 0.4 -1.8 -0.5 0.6 -0.1 1.5
Gout (self-reported) 0.2 0.2 0.8 0.7 -0.3 -0.4 -0.2 0.4 -0.4 -0.1 -0.9
Hypothyroidism/myxoedema (self-reported) 0.3 0.6 1.7 0.7 0.1 1.2 -0.1 0.1 -0.7 -0.6 -1.3
Medication: Amlodipine 0.3 0.4 1.5 0.5 -0.5 -0.2 -1.2 -0.8 -0.2 -0.6 0.4
Medication: Ventolin 100micrograms inhaler 0.2 0.3 0.5 0.3 -0.7 0.6 0.7 -0.2 0.3 -0.3 -0.7
Birth weight 0.8 1.8 6.1 -0.1 -0.2 -2.2 0.3 -1.0 -0.0 -2.5 1.5
Chronic bronchitis/emphysema (mother) 0.5 0.6 2.1 -0.4 0.2 0.6 -1.0 0.6 -1.4 0.8 0.2
High blood pressure (siblings) 0.4 0.5 1.7 0.4 -0.4 -0.8 -0.5 0.2 1.3 -0.6 1.0
Forced vital capacity (FVC), Best measure 0.6 2.1 6.2 -2.2 1.1 -0.5 1.4 1.0 1.2 -0.1 2.5
Body fat percentage 0.2 0.9 4.0 -0.1 -0.6 -2.0 -1.6 -0.1 0.6 -0.1 -0.1
Leg fat percentage (right) 0.3 1.1 5.5 0.4 -0.7 -1.3 -2.3 0.0 0.6 0.5 -0.1
Arm fat-free mass (right) 1.1 5.9 16.6 -0.8 -2.3 -4.1 0.8 -2.5 3.0 -2.4 1.7
Exposure to tobacco smoke outside home 1.8 2.4 7.3 1.4 -1.0 -1.1 -1.2 -1.6 -1.0 -2.7 -1.6
Comparative body size at age 10 0.2 0.5 3.1 -0.5 -0.1 0.2 0.4 0.3 0.3 0.8 1.8
Number of full brothers 0.3 0.4 1.3 0.1 -0.6 -0.8 0.6 -0.3 0.7 0.1 -1.1
Worry too long after embarrassment 1.0 1.7 5.4 0.5 -1.5 -0.9 0.9 -1.7 0.4 -2.3 0.9
Seen a psychiatrist for nerves, anxiety, tension or depression 0.6 0.8 3.9 -0.9 0.2 -1.0 2.0 0.4 0.2 -0.2 0.4
Wheeze or whistling in the chest in last year 1.2 2.1 7.9 2.8 -1.6 0.1 0.2 -1.2 -0.2 0.2 -2.1
Number of children fathered 1.0 1.2 4.5 0.2 0.5 -0.8 -0.7 0.1 1.8 0.4 2.1
Reason for reducing amount of alcohol drunk: Health precaution 1.2 1.4 2.9 -1.3 1.2 -0.3 0.3 1.3 -0.7 1.7 1.6
Age at first live birth 0.3 0.5 1.8 1.1 0.5 0.6 -0.8 -0.0 0.1 -1.3 0.1
Pulse wave peak to peak time 1.4 1.6 6.5 -2.6 0.2 -0.8 1.5 1.0 0.8 0.8 1.1
Health satisfaction 1.3 1.7 6.4 0.1 -0.3 2.5 -0.4 -0.2 1.8 -1.4 1.2
Shortness of breath walking on level ground 1.1 1.3 2.9 0.8 -1.1 0.2 1.2 -1.3 -0.5 -1.7 -1.5
Qualifications: College or University degree 0.1 0.3 0.9 1.0 0.3 0.4 -0.0 -0.0 -0.6 0.5 0.7
Eye problems/disorders: None of the above 0.4 0.5 1.7 -0.0 0.3 -1.0 0.6 0.6 -1.3 0.2 -0.6
Mouth/teeth dental problems: Loose teeth 1.1 1.3 3.9 0.1 -1.2 -0.9 -0.5 -2.0 -0.2 -1.7 0.9
Emphysema/chronic bronchitis 1.7 1.9 8.0 1.4 -1.4 -2.8 0.3 -1.2 -0.0 -1.3 -0.1
Medication for pain relief, constipation, heartburn 0.7 1.2 2.2 -0.7 1.3 0.2 -0.6 1.5 -1.5 0.8 -1.4
Neck or shoulder pain in last month 0.5 0.8 2.5 1.6 -0.7 0.8 0.7 -0.8 -0.6 0.2 -1.1
Medication: Blood pressure 0.4 0.6 1.7 -1.3 0.6 -0.6 0.5 0.6 0.9 -0.5 1.0
Angina (self-reported) 1.2 1.5 3.4 1.5 -1.1 1.5 -1.8 -1.5 0.2 -0.8 0.6
Migraine (self-reported) 2.4 2.9 6.3 -1.8 0.6 0.7 2.0 1.7 2.5 1.4 2.1
Medication: Ibuprofen 0.2 0.3 0.7 -0.6 -0.2 0.0 0.5 -0.0 0.9 -0.3 0.8
Medication: Allopurinol 0.3 0.5 1.4 -0.0 1.1 -0.6 -0.2 1.2 -0.4 0.5 -0.5
Medication: Omeprazole 1.7 2.1 4.9 1.3 -1.8 -1.0 0.3 -2.0 1.2 -2.2 0.8
Medication: Seretide 50 evohaler 1.8 2.0 4.9 1.9 -2.2 -0.7 1.4 -2.1 0.3 -0.9 0.2
Mean time to correctly identify matches 0.2 0.5 1.1 -1.0 0.6 0.3 -1.0 0.5 0.2 0.9 0.4
Heart disease (mother) 0.3 0.4 1.0 -0.3 -0.2 1.0 0.8 0.7 0.3 0.8 0.4
Reproduciblity of spirometry measurement using ERS/ATS criteria 1.2 1.4 4.2 1.1 -1.2 -0.4 -0.3 -2.0 -0.8 -1.4 -1.2
Whole body fat mass 0.4 1.8 8.9 -0.4 -1.2 -3.0 -0.6 -0.9 1.2 -1.0 0.2
Leg fat mass (right) 0.4 1.5 6.0 0.3 -1.2 -2.5 -1.5 -0.9 0.9 -0.6 -0.1
Arm predicted mass (right) 1.2 5.9 17.9 -0.7 -2.4 -4.2 1.0 -2.5 2.8 -2.5 1.5
Pulse rate, automated reading 0.2 0.8 2.0 1.3 -0.1 0.3 -0.8 -0.2 -1.1 0.7 -1.4
Alcohol intake frequency. 0.5 1.2 3.9 1.1 -0.7 0.6 -0.3 -1.1 0.5 -1.3 -2.0
Comparative height size at age 10 0.9 4.7 13.0 0.7 -2.1 -3.6 1.8 -2.5 0.6 -3.0 -0.8
Number of full sisters 0.7 0.9 2.7 0.2 0.6 -1.6 1.4 0.1 -0.5 -0.6 1.2
Suffer from ‘nerves’ 0.2 0.3 0.8 -0.3 0.0 0.7 0.2 -0.1 0.4 -0.8 0.9
Overall health rating 0.8 1.6 4.9 2.0 -1.5 0.6 0.8 -0.7 0.6 -0.3 -2.2
Chest pain or discomfort 0.3 0.5 2.3 0.2 0.6 1.5 -0.5 0.8 0.6 0.1 -0.1
Had major operations 1.0 1.2 2.4 1.6 -1.4 0.1 1.1 -1.1 -0.6 -0.3 -1.4
Age at last live birth 0.3 0.4 2.4 0.1 1.6 0.1 0.1 0.8 0.4 -0.3 -0.2
Family relationship satisfaction 1.9 2.3 7.3 -2.5 0.6 1.4 0.4 0.7 0.6 1.2 2.7
Leg pain on walking 0.7 0.8 3.0 0.9 -0.2 0.8 -1.7 -0.1 1.4 -0.1 0.2
Qualifications: NVQ or HND or HNC or equivalent 1.5 1.9 5.5 2.4 -1.5 -0.8 0.8 -1.8 -0.7 -0.8 -1.2
Commuting to job workplace: Car/motor vehicle 0.9 1.0 3.4 0.3 -1.1 -0.3 -0.2 -0.8 1.8 0.8 1.4
Illness, injury, bereavement, stress in last 2 years 0.5 0.6 2.0 -0.6 0.8 0.3 0.5 1.2 0.1 1.4 0.0
Medication: Aspirin 0.7 0.9 3.4 -1.0 0.7 0.0 1.8 0.9 0.0 0.4 1.1
Supplements: Vitamin C 0.2 0.3 0.8 0.1 -0.9 0.2 -0.1 -0.7 0.3 0.8 -0.6
Knee pain experienced in last month 1.8 2.8 5.8 2.1 -2.0 -1.3 -0.3 -2.3 0.6 -2.4 -0.5
Hypertension (Self-reported) 0.5 1.4 3.5 0.3 -0.8 -1.7 1.4 -0.8 0.6 -1.9 -0.9
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 1.0 1.1 3.2 0.8 -1.3 -0.2 1.8 -0.8 1.7 -0.1 0.1
Illnesses of father: Heart disease 0.1 0.2 0.5 -0.6 -0.1 0.2 0.5 0.7 0.5 0.3 -0.4
Illnesses of siblings: Diabetes 1.6 2.0 3.9 1.5 -1.3 0.7 0.3 -1.7 -0.8 -1.9 -2.0
Smoking status: Previous 0.2 0.4 1.6 0.4 0.2 0.7 -0.3 0.3 -1.2 0.5 -0.4
Forced expiratory volume in 1-second (FEV1), predicted 1.7 3.5 9.0 -1.4 -1.0 -3.0 2.3 -1.1 1.8 -2.0 1.6
Whole body fat-free mass 1.2 6.9 18.5 -0.5 -2.7 -4.3 1.8 -3.0 2.6 -3.0 1.3
Leg fat-free mass (right) 1.0 5.1 16.0 -0.6 -2.0 -4.0 1.8 -2.4 1.7 -2.8 0.7
Arm fat percentage (left) 0.2 0.6 2.7 0.1 -0.4 -1.6 -1.3 -0.3 0.3 -0.0 -0.4
Average weekly red wine intake 1.9 2.8 4.7 -2.2 2.0 -1.5 1.2 1.9 0.5 1.5 2.0
Handedness (chirality/laterality): Left-handed 0.7 0.8 2.9 -0.5 0.8 1.7 -0.7 0.7 -0.3 1.2 0.2
Mood swings 0.7 1.3 3.2 0.8 -1.7 0.5 0.8 -1.8 0.4 -1.4 -0.6
Loneliness, isolation 0.6 0.9 2.1 -0.4 -1.3 -0.5 -0.1 -1.5 0.7 -1.4 0.6
Long-standing illness, disability or infirmity 0.9 1.3 3.6 1.6 -0.6 1.2 0.6 -1.2 -0.8 -0.1 -1.9
Ever had bowel cancer screening 0.5 0.6 3.0 -0.4 -0.1 0.0 -1.7 -0.4 0.8 -0.2 1.1
Diabetes diagnosed by doctor 0.8 1.3 6.8 1.0 -1.0 -0.2 -0.0 -1.0 -0.4 -0.7 -2.6
Ever had stillbirth, spontaneous miscarriage or termination 0.6 0.6 1.8 0.8 -0.8 -0.6 -0.5 -1.3 0.4 -0.9 -0.1
Friendships satisfaction 1.1 1.3 5.7 0.5 -0.5 2.4 -0.3 -0.5 -0.4 -1.3 1.5
Qualifications: nursing, teaching 0.6 0.9 3.2 -0.5 0.1 -1.3 0.3 0.4 1.2 1.8 0.7
Commuting to job workplace: Walk 0.7 0.8 1.4 1.2 0.7 0.6 1.1 1.1 -0.8 0.7 -0.6
Eye problems/disorders: Cataract 0.6 0.6 1.6 1.3 -0.3 0.7 -0.9 -0.5 0.2 -1.2 0.6
Mouth/teeth dental problems: Mouth ulcers 0.4 0.6 1.4 0.5 0.0 1.2 -0.8 -0.3 0.5 0.7 -1.1
Medication for cholesterol 0.5 0.7 1.5 -1.2 0.8 -0.1 0.9 0.7 -0.7 -0.3 1.2
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.6 0.7 2.2 0.5 -1.5 0.4 0.3 -1.1 0.7 0.1 -1.2
Back pain experienced in last month 0.6 0.9 3.7 0.1 0.5 1.9 -1.2 -0.5 -0.3 -0.6 -0.8
Mineral and other dietary supplements 0.6 0.8 2.3 -1.2 0.2 0.7 -0.1 0.6 1.1 0.6 1.5
Breast cancer (self-reported) 2.5 3.0 9.6 3.1 -0.2 0.7 -0.3 -0.3 -1.5 -1.2 -3.1
Asthma (self-reported) 0.8 1.6 4.1 2.0 -1.1 0.7 2.0 -0.3 0.5 0.8 -1.5
Osteoporosis (self-reported) 1.1 1.4 7.2 0.7 -0.1 -0.4 -2.7 0.0 1.4 -1.1 0.4
Osteoarthritis (self-reported) 0.8 1.0 2.0 1.1 -0.7 0.8 -1.4 -1.4 0.2 -1.1 -0.8
Medication: Aspirin 0.6 0.7 4.8 -0.6 0.1 0.2 2.2 0.7 0.1 0.1 0.4
Medication: Gliclazide 0.5 0.6 2.4 -0.7 -0.6 -0.2 1.1 0.3 -0.1 -0.5 -1.6
Illnesses of father: None of the above (group 1) 0.4 0.4 1.5 0.4 -0.5 -1.2 0.6 -0.8 0.4 -0.0 0.6
Smoking status: Current 0.6 0.9 2.3 -0.2 -1.3 -0.2 1.2 -0.2 1.3 1.5 -0.0
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.9 2.0 5.2 -1.6 1.3 -0.2 0.8 1.8 1.3 1.0 2.3
Whole body water mass 1.1 6.5 18.1 -0.6 -2.5 -4.2 1.7 -2.9 2.4 -3.0 1.3
Leg predicted mass (right) 1.0 5.1 15.8 -0.5 -2.0 -4.0 1.8 -2.4 1.7 -2.8 0.6
Arm fat mass (left) 0.4 1.7 6.4 -0.2 -1.4 -2.5 -1.0 -1.2 1.4 -0.9 0.3
Number of self-reported non-cancer illnesses 1.0 1.8 4.6 1.7 -1.4 -1.1 1.3 -1.3 2.1 -0.9 -0.0
Average weekly champagne plus white wine intake 0.9 1.2 3.0 -1.3 1.4 0.1 1.1 1.7 0.9 0.8 0.2
Miserableness 0.5 0.8 2.6 0.6 -0.8 1.6 0.4 -0.7 -0.7 -1.4 -0.1
Guilty feelings 0.9 1.3 5.6 0.9 -1.1 0.0 -0.3 -1.5 -0.7 -2.4 0.3
Wears glasses or contact lenses 1.2 1.3 4.7 -0.5 0.8 0.6 2.2 1.3 -1.1 0.6 1.2
Ever taken oral contraceptive pill 1.8 2.0 8.5 -2.9 1.4 -1.1 0.0 0.9 -0.6 0.9 1.5
Hearing aid user 0.3 0.3 0.7 0.7 0.0 -0.5 0.6 0.4 -0.3 0.8 -0.8
Mother’s age at death 1.3 1.6 6.0 0.4 -1.0 -1.0 2.4 -1.0 0.1 -1.6 1.0
Financial situation satisfaction 1.2 1.4 4.0 -0.2 -1.4 -0.4 0.6 -2.0 0.8 -1.9 0.8
Tinnitus: Yes, now most or all of the time 0.6 0.7 1.9 1.4 0.0 0.8 -1.0 0.6 -0.4 0.1 -1.3
Commuting to job workplace: Public transport 1.2 1.5 3.5 -0.7 1.8 0.9 0.9 1.9 -1.3 0.7 -0.9
Eye problems/disorders: Glaucoma 1.1 1.3 5.6 -0.9 0.6 1.0 -1.7 -0.1 -0.2 0.0 2.4
Medication: Blood pressure 0.6 1.2 2.4 1.3 -1.1 -0.3 -1.0 -1.3 0.6 -1.3 -1.6
Pain type(s) experienced in last month: Hip pain 1.0 1.3 6.4 2.5 -0.6 0.5 0.5 -0.9 -0.5 -0.5 -1.4
Supplements: Fish oil (including cod liver oil) 1.1 1.5 2.8 1.1 -0.7 -0.6 -1.1 -1.5 -1.7 -1.0 -1.6
High cholesterol (Self-reported) 0.3 0.6 1.6 1.3 0.3 0.1 -0.8 0.4 0.2 -1.1 -1.1
Medication: Bendroflumethiazide 0.4 0.7 1.4 0.6 -0.7 -0.2 -0.4 -0.4 1.2 -1.2 -1.1
Medication: Paracetamol 0.3 0.4 1.3 1.1 -0.6 0.4 0.6 -0.5 0.6 -0.8 -0.1
Medication: Lisinopril 0.3 0.4 1.6 -0.7 0.3 -0.4 0.5 0.2 0.9 -1.3 -0.0
Medication: Atorvastatin 0.4 0.5 2.0 -0.6 0.7 0.1 0.7 1.4 0.7 0.1 0.5
Illnesses of father: High blood pressure 0.4 0.5 2.0 -0.7 0.1 0.2 1.1 0.5 1.4 0.3 0.2
Alcohol drinker status: Never 0.5 0.7 2.3 0.3 0.7 1.5 0.7 0.7 0.2 1.1 -0.4
Ever smoked 1.1 2.0 5.6 1.5 -0.4 1.4 -0.4 -0.9 -2.4 0.6 -2.0
Basal metabolic rate 1.2 6.5 18.0 -0.4 -2.7 -4.2 1.4 -3.0 2.4 -2.9 1.2
Leg fat percentage (left) 0.2 0.9 3.6 0.1 -0.6 -1.4 -1.9 0.1 0.7 0.7 -0.0
Arm fat-free mass (left) 1.1 5.4 13.0 -0.3 -2.8 -3.6 0.7 -2.9 2.3 -2.6 1.2
Number of operations (self-reported) 1.5 2.3 8.6 2.9 -1.5 0.8 0.1 -1.2 0.0 -1.4 -1.8
Average weekly beer plus cider intake 0.1 0.2 0.8 -0.9 -0.4 0.3 -0.1 -0.3 -0.1 0.3 0.6
Irritability 0.5 0.9 3.4 -0.4 0.4 -0.1 1.5 0.6 0.1 -0.8 1.8
Risk taking 0.9 1.3 2.8 -0.5 0.1 -1.7 1.0 0.8 1.6 1.5 0.9
Ever had prostate specific antigen (PSA) test 0.6 0.7 2.2 0.9 -0.7 -0.1 1.5 -0.2 -0.7 -1.1 0.5
Fractured/broken bones in last 5 years 1.6 2.1 6.3 -0.8 1.0 1.4 1.3 2.2 0.5 2.5 0.0
Age started oral contraceptive pill 1.1 1.4 3.2 1.3 -1.6 -0.1 -0.8 -1.8 -0.2 -1.7 0.5
Diastolic blood pressure, automated reading 0.3 0.9 2.9 -1.7 0.6 -1.3 0.9 0.8 0.6 -0.6 0.2
Ever depressed for a whole week 1.2 1.5 3.3 0.7 -1.8 1.8 0.5 -1.3 0.6 -1.3 -1.0
Unable to work because of sickness or disability 0.9 1.1 2.9 1.1 -1.7 1.0 1.0 -1.6 0.3 -0.6 -0.2
Commuting to job workplace: Cycle 0.8 1.0 4.1 0.0 0.7 -1.5 2.0 0.5 -0.6 -0.1 -0.8
Myopia 0.5 0.8 3.0 -0.6 0.7 -0.0 1.3 0.7 -1.7 -0.2 -0.4
Vascular/heart problems diagnosed by doctor 0.6 1.7 4.4 -0.5 1.5 1.6 -0.8 1.7 -0.4 2.1 0.3
Cholesterol lowering medication 1.1 1.7 4.4 2.1 -1.1 -0.0 -1.4 -0.9 0.1 -1.1 -1.9
Medication: Omeprazole (e.g. Zanprol) 1.9 2.3 5.5 2.3 -2.0 -0.8 0.9 -1.8 1.5 -1.4 0.4
Pain experienced in last month 1.2 2.1 5.1 -1.7 1.6 -0.5 -0.1 1.8 -1.5 2.2 -0.0
Supplements: Calcium 0.5 0.5 1.4 0.2 0.1 1.0 -0.6 -0.1 -0.5 -1.2 -1.1
Basal cell carcinoma (self-reported) 1.4 1.6 7.6 0.8 -0.7 0.5 0.1 -1.3 -2.8 -0.7 -1.4
Heart attack/myocardial infarction (self-reported) 0.4 0.6 1.1 -0.2 -0.9 -0.4 0.9 -0.7 0.4 -0.9 1.0
Deep venous thrombosis (DVT) (self-reported) 1.7 2.2 4.6 1.5 -1.3 0.1 1.8 -1.8 1.2 -2.1 -1.2
Heart disease (siblings) 0.4 0.5 1.0 -0.4 -0.9 -0.9 0.1 -0.6 0.9 -1.0 0.6
Alcohol drinker status: Previous 0.1 0.2 0.5 -0.6 0.7 -0.0 0.2 0.2 -0.4 0.2 -0.5
Pack years of smoking 1.0 1.5 5.5 1.1 -0.4 1.5 -0.8 0.5 -0.1 1.3 -2.3
Impedance of whole body 0.4 2.2 5.4 -1.7 2.0 1.4 0.2 2.3 0.0 1.8 0.5
Leg fat mass (left) 0.4 1.4 7.1 0.2 -1.2 -2.7 -1.0 -0.8 1.0 -0.6 -0.1
Arm predicted mass (left) 1.1 5.7 14.6 -0.4 -2.9 -3.8 0.8 -2.9 2.4 -2.6 1.2