TWAS hub - MPRIP

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Nerve Tibial	0.1223	0.0489	3.2e-03	0.098	NA	0.084	NA	0.097	1.9e-07	NA	1.4e-06	NA	2.2e-07
2	METSIM	Adipose	0.0412	0.0164	5.8e-04	0.039	0.020	0.040	0.022	0.038	1.5e-06	3.9e-04	1.2e-06	2.7e-04	1.8e-06
3	ROSMAP	Brain Pre-frontal Cortex	0.1447	0.0332	1.8e-10	0.111	0.093	0.109	0.111	0.106	4.6e-14	5.1e-12	6.9e-14	4.1e-14	1.8e-13
4	TCGA	Breast Invasive Carcinoma	0.0178	0.0095	5.8e-04	0.020	0.010	0.010	NA	0.013	3.7e-05	2.5e-03	3.5e-03	NA	9.1e-04
5	TCGA	Colon Adenocarcinoma	0.0720	0.0400	2.5e-03	0.018	0.055	0.029	NA	0.027	3.2e-02	4.3e-04	7.8e-03	NA	1.1e-02
6	TCGA	Head and Neck Squamous Cell Carcinoma	0.0359	0.0173	2.6e-04	0.028	0.031	0.027	NA	0.027	3.5e-04	1.9e-04	4.4e-04	NA	4.7e-04
7	TCGA	Kidney Renal Clear Cell Carcinoma	0.0448	0.0246	1.4e-04	0.021	0.038	0.039	NA	0.035	1.9e-03	3.5e-05	2.6e-05	NA	6.6e-05
8	TCGA	Prostate Adenocarcinoma	0.0627	0.0311	4.8e-05	0.044	0.051	0.049	NA	0.037	2.2e-05	4.6e-06	7.6e-06	NA	8.1e-05
9	TCGA	Thyroid Carcinoma	0.0520	0.0230	2.1e-05	0.015	0.038	0.043	NA	0.036	1.2e-02	1.2e-04	4.3e-05	NA	1.9e-04

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Eye problems/disorders: Diabetes related eye disease	5.7	6.3	9.6	-0.7	-2.0	2.4	2.4	3.0	2.3	2.7	3.1	3.0
Pulse rate, automated reading	5.4	17.3	30.9	-1.0	-4.8	3.1	3.4	5.1	3.4	4.8	4.4	5.6
Father’s age at death	5.0	6.7	10.4	-0.5	-2.1	2.7	2.7	3.1	2.5	2.9	2.6	3.2
Seen a psychiatrist for nerves, anxiety, tension or depression	3.9	5.1	11.7	-1.3	-1.6	2.1	2.4	1.9	2.4	1.8	3.4	2.8
Reason for reducing amount of alcohol drunk: Health precaution	3.6	4.2	6.9	-1.2	-1.5	2.0	1.9	2.6	2.2	2.4	2.0	2.3
Mood swings	3.1	5.5	9.0	-1.7	0.3	3.0	2.9	1.9	2.7	2.5	3.0	1.8
Medication for cholesterol	3.1	4.7	6.9	-2.3	0.2	2.4	2.5	2.0	2.6	2.2	2.3	1.9
Worrier / anxious feelings	3.0	5.6	10.9	-1.7	1.8	3.0	3.3	1.3	2.4	2.3	3.2	1.3
Coronary Artery Disease (CAD)	2.9	3.4	6.8	-1.3	-0.9	2.0	1.6	2.6	1.5	2.4	1.5	2.1
Number of live births	2.9	4.2	8.4	1.8	0.0	-2.2	-2.2	-2.1	-2.9	-2.0	-2.0	-1.9
Frequency of tenseness / restlessness in last 2 weeks	2.6	4.1	8.0	-1.3	0.6	2.4	2.8	1.4	2.6	1.6	2.7	1.5
Osteoporosis (self-reported)	2.5	3.0	5.9	-2.4	0.6	1.8	1.6	2.4	1.4	2.4	1.3	0.9
Illnesses of father: None of the above (group 1)	2.5	3.1	7.8	-1.1	2.8	1.7	2.1	1.4	2.5	0.6	1.8	0.0
Illnesses of father: Heart disease	2.4	3.3	7.7	1.9	-2.8	-2.1	-2.2	-1.3	-1.9	-1.3	-1.4	-0.0
Frequency of depressed mood in last 2 weeks	2.3	3.2	6.8	-2.2	1.8	1.6	2.2	0.4	2.6	0.9	2.2	0.6
Reproduciblity of spirometry measurement using ERS/ATS criteria	2.3	2.7	4.5	-0.4	0.0	1.9	2.0	1.9	2.1	1.7	1.5	1.7
Miserableness	2.3	4.0	7.8	-1.8	2.1	2.5	2.5	0.5	2.5	1.1	2.8	0.6
Pulse rate	2.2	3.7	6.9	-1.6	-1.6	1.2	1.6	1.9	2.2	1.9	2.2	2.6
Number of full brothers	2.2	2.7	5.3	0.7	0.5	-2.0	-2.0	-1.5	-1.3	-2.3	-2.0	-1.5
Medication: Allopurinol	2.2	2.9	6.8	0.1	0.8	2.6	2.2	1.8	1.7	2.0	1.3	1.4
Cholesterol lowering medication	2.2	3.2	7.3	1.4	-0.7	-1.9	-2.2	-1.6	-2.7	-1.2	-2.0	-1.6
Depressed Affect (Nagel 2018)	2.1	4.3	9.2	-2.2	1.0	2.4	2.5	1.1	2.6	1.7	3.0	1.3
Tinnitus: Yes, but not now, but have in the past	2.1	2.2	4.2	0.7	0.4	-1.7	-1.6	-1.4	-2.1	-1.1	-1.9	-1.7
Ovarian Cancer	2.0	2.7	5.2	2.0	1.2	-1.5	-1.1	-1.5	-1.0	-2.1	-2.3	-1.5
Other serious medical condition/disability diagnosed by doctor	2.0	2.6	6.0	-0.8	-0.5	2.0	2.0	1.1	1.3	1.5	2.4	1.6
Medication: Ramipril	2.0	2.5	5.0	2.2	0.9	-0.8	-1.4	-1.8	-2.0	-1.8	-1.6	-1.3
Qualifications: O levels/GCSEs or equivalent	2.0	3.3	5.2	-0.4	-1.8	2.1	1.9	1.5	1.3	2.3	2.1	2.0
Qualifications: College or University degree	2.0	6.3	11.8	-2.3	-0.8	2.4	2.4	3.1	3.4	2.5	2.4	2.6
Loneliness, isolation	2.0	2.7	6.0	-2.1	0.7	1.6	1.8	1.0	2.0	1.2	2.5	1.0
Medication: Blood pressure	2.0	3.7	8.8	2.5	0.1	-1.7	-2.2	-1.1	-3.0	-1.4	-2.3	-1.8
Heel T-Score	1.9	15.1	28.8	-0.5	4.5	-3.0	-2.9	-5.4	-2.3	-4.6	-4.2	-5.1
Medication for hormone replacement therapy	1.9	2.1	4.0	0.3	0.8	-1.9	-1.5	-1.9	-0.9	-2.0	-1.2	-1.7
Severe depression (siblings)	1.9	2.1	4.5	0.3	-0.3	-2.1	-2.0	-1.4	-1.8	-1.3	-1.4	-1.2
Medication: Aspirin	1.9	2.5	5.2	-0.2	0.4	-1.8	-2.3	-1.2	-2.3	-0.8	-2.0	-1.7
Medication: Gliclazide	1.9	2.1	5.2	1.1	-0.0	-1.8	-1.5	-1.5	-2.3	-1.5	-0.9	-1.4
Basal cell carcinoma (self-reported)	1.9	2.3	4.9	-1.4	0.1	1.5	1.7	1.6	2.2	1.2	1.1	1.9
Type 2 Diabetes (T2D) (2012)	1.8	2.1	5.1	1.1	-0.6	-1.9	-1.6	-1.0	-1.6	-1.3	-2.2	-0.8
Medication: Atorvastatin	1.8	2.3	4.6	1.8	0.6	-1.2	-1.6	-1.2	-2.1	-1.1	-1.5	-1.8
Alcohol drinker status: Never	1.8	2.2	3.7	-1.0	-1.8	1.4	1.2	1.5	1.0	1.9	1.3	1.9
Hair/balding pattern: Pattern 2	1.7	2.1	3.7	-0.9	-1.7	1.0	1.1	1.8	1.7	1.3	1.2	1.9
Impedance of arm (left)	1.7	7.7	15.9	1.0	-0.7	-3.4	-4.0	-1.9	-3.3	-2.2	-4.0	-2.3
Falls in the last year	1.6	2.2	4.6	-2.1	1.5	1.3	1.7	0.8	1.9	1.3	1.6	0.5
Hair/balding pattern: Pattern 3	1.6	2.5	4.9	2.2	-0.4	-1.5	-1.7	-1.4	-2.0	-1.5	-1.3	-1.4
Pulse wave peak to peak time	1.6	1.9	5.2	1.1	-0.7	-1.3	-1.4	-1.2	-2.3	-0.2	-1.8	-1.3
Medication: Ibuprofen	1.6	1.9	3.7	-1.1	0.9	1.8	1.9	0.9	1.4	1.7	1.4	0.5
Financial situation satisfaction	1.6	2.0	4.8	0.9	2.2	-1.0	-0.8	-1.7	-0.5	-2.1	-0.9	-1.5
HbA1C	1.5	1.7	6.9	2.6	-0.7	-1.2	-1.4	-1.0	-1.2	-1.2	-0.7	-0.4
Multivitamins +/- minerals	1.5	1.9	5.2	0.9	0.9	-1.1	-1.5	-1.1	-1.1	-1.6	-2.3	-1.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.5	1.8	3.8	-0.8	-0.6	-1.6	-1.8	-2.0	-1.1	-1.7	-0.9	-0.7
Mean Putamen Volume	1.4	1.6	4.9	-0.0	-0.1	-1.6	-1.9	-0.7	-1.1	-1.1	-2.2	-0.7
Heel bone mineral density (BMD) T-score, automated (left)	1.4	3.1	6.2	1.2	0.8	-1.7	-1.5	-2.5	-1.6	-2.0	-1.8	-2.0
Waist circumference	1.4	5.2	9.1	0.6	-1.8	2.5	2.5	2.4	1.1	3.0	2.7	2.7
Heel bone mineral density (BMD) T-score, automated (right)	1.4	3.3	6.3	0.4	0.7	-1.9	-1.8	-2.5	-1.7	-2.1	-2.1	-2.0
Pulse wave Arterial Stiffness index	1.4	1.6	5.0	-1.1	0.5	1.2	1.3	1.1	2.2	0.1	1.6	1.2
Length of working week for main job	1.4	1.6	2.6	-0.8	-0.9	1.2	1.2	1.5	1.6	1.2	1.0	1.6
Leg pain on walking	1.4	1.8	7.3	-2.7	2.4	-0.1	-0.1	-0.7	0.1	-0.2	0.1	-1.5
Neuroticism (Nagel 2018)	1.3	3.0	5.2	-1.7	2.1	2.2	2.3	0.4	1.6	1.4	2.1	0.3
Crohns Disease (2012)	1.3	2.1	5.7	-2.4	2.4	-1.0	-1.1	-1.1	0.0	-1.0	-1.1	-1.4
Mouth/teeth dental problems: Dentures	1.3	2.1	4.9	-0.4	-1.8	1.1	1.2	1.6	0.5	1.6	2.2	1.7
Forced expiratory volume in 1-second (FEV1), Best measure	1.3	4.0	7.7	1.2	-0.4	-2.2	-2.0	-2.5	-2.8	-2.0	-1.4	-2.3
Average weekly red wine intake	1.3	1.9	4.2	0.4	-0.2	-1.5	-1.8	-1.6	-0.9	-1.5	-2.1	-1.2
Medication: Bendroflumethiazide	1.3	1.9	6.7	2.6	-1.1	-1.0	-1.4	-0.7	-1.9	-1.1	-0.8	-0.4
Medication: Paracetamol	1.3	2.0	5.3	-1.5	0.4	1.4	1.8	0.9	2.3	0.8	1.6	1.2
Impedance of whole body	1.3	6.4	14.6	1.1	-2.4	-3.2	-3.7	-0.9	-2.8	-1.4	-3.8	-1.1
Ulcerative Colitis	1.2	1.7	3.2	-0.9	1.1	-1.6	-1.8	-1.2	-0.8	-1.4	-1.4	-1.3
Average weekly spirits intake	1.2	1.5	3.1	0.9	0.3	1.7	1.8	1.4	1.2	1.3	0.8	0.9
Impedance of leg (right)	1.2	5.8	14.6	1.3	-3.8	-2.7	-3.3	0.1	-2.5	-0.4	-3.4	-0.1
Taking other prescription medications	1.2	1.9	4.8	1.0	-1.9	-1.7	-1.5	-1.1	-2.2	-0.8	-0.6	-0.6
Impedance of leg (left)	1.2	5.7	16.6	1.0	-4.1	-2.9	-3.1	0.3	-2.1	-0.5	-3.3	0.1
Ever unenthusiastic/disinterested for a whole week	1.2	1.4	2.3	-1.5	1.3	1.3	1.3	0.9	1.4	1.2	1.1	0.2
Mouth/teeth dental problems	1.2	1.8	5.3	1.2	1.0	-1.2	-1.4	-0.8	-0.4	-1.6	-2.3	-1.1
Impedance of arm (right)	1.2	5.8	12.4	0.6	-0.5	-2.8	-3.5	-1.7	-2.9	-1.9	-3.5	-2.0
Glaucoma (self-reported)	1.2	1.4	2.5	1.3	-0.8	-1.5	-1.6	-0.4	-1.3	-0.9	-1.5	-0.7
Forced vital capacity (FVC), Best measure	1.2	4.5	9.6	1.5	-0.5	-2.3	-2.1	-2.5	-3.1	-2.0	-1.6	-2.5
Supplements: Vitamin C	1.2	1.4	9.8	-0.1	-3.1	-0.9	-0.7	0.5	-0.2	0.3	-0.3	1.2
Hypertension (Self-reported)	1.2	3.4	6.2	2.3	0.1	-1.6	-2.0	-1.3	-2.4	-1.6	-2.5	-1.5
Illnesses of siblings: Diabetes	1.2	1.4	3.2	-1.0	-1.0	0.8	1.0	1.0	1.2	1.2	1.4	1.8
Qualifications: nursing, teaching	1.2	1.9	3.2	-0.7	-0.0	1.7	1.4	1.7	1.8	1.5	1.2	1.3
Tinnitus: Yes, now most or all of the time	1.2	1.4	4.0	-1.7	2.0	0.1	-0.4	-1.7	0.0	-0.9	0.3	-1.3
Arm predicted mass (left)	1.2	5.9	13.4	-0.3	-1.0	2.7	3.2	2.0	2.1	2.6	3.7	2.3
Alzheimer’s Disease (in mother)	1.1	1.3	2.6	0.8	-0.2	1.6	1.5	1.1	1.2	1.4	0.9	1.0
Neuroticism (2016)	1.1	1.6	3.8	-1.9	0.9	1.4	1.4	0.1	1.1	1.4	1.6	0.1
Schizophrenia (2014)	1.1	2.5	6.7	-0.6	-1.5	1.4	1.7	1.4	0.8	1.6	2.6	1.9
Cardiovascular Disease	1.1	3.7	6.2	2.0	-0.2	-1.9	-2.1	-1.9	-2.5	-1.9	-2.3	-1.6
Serious illness, injury or assault to yourself	1.1	1.4	2.1	1.2	-1.0	1.4	1.1	1.4	0.6	1.2	1.3	1.1
Supplements: Glucosamine	1.1	1.5	3.4	-0.6	-0.6	1.3	1.1	1.8	1.4	1.3	1.0	1.2
Qualifications: None of the above	1.1	2.4	4.4	0.1	0.6	-2.0	-2.0	-1.4	-2.1	-1.5	-1.4	-1.7
Age at last live birth	1.1	1.6	3.1	1.8	-0.2	-1.4	-1.1	-1.3	-0.9	-1.8	-1.2	-0.8
Mouth/teeth dental problems: Mouth ulcers	1.1	1.8	3.8	-1.9	-0.0	1.1	1.2	1.4	1.4	1.5	1.4	1.2
Fractured/broken bones in last 5 years	1.1	1.4	3.3	-1.8	0.3	1.3	1.2	1.1	1.4	1.1	1.2	0.8
Deep venous thrombosis (DVT) (self-reported)	1.1	1.4	3.5	-0.4	1.0	1.2	1.6	0.9	0.8	1.4	1.9	-0.1
Prostate Cancer	1.0	1.4	3.7	1.0	-0.4	1.0	1.7	0.5	1.9	0.3	1.2	1.6
LDL Cholesterol	1.0	1.6	4.1	1.8	-1.2	-1.1	-1.2	-0.6	-2.0	-0.3	-1.2	-0.9
Systolic Blood Pressure	1.0	5.2	14.1	1.3	0.9	-2.2	-2.4	-2.1	-2.6	-2.1	-3.8	-2.0
Respiratory disease	1.0	2.3	4.5	-0.2	-1.6	1.2	1.5	1.8	0.9	2.1	1.6	1.8
High blood pressure	1.0	2.9	6.1	2.2	-0.1	-1.5	-1.9	-0.9	-2.3	-1.4	-2.5	-1.2
Pulse wave reflection index	1.0	1.3	3.6	0.9	1.9	-0.4	-0.1	-1.2	0.1	-1.9	-0.4	-1.4
Medication: Ventolin 100micrograms inhaler	1.0	1.3	2.5	-1.1	0.0	1.4	1.5	1.0	1.6	1.1	0.8	1.1
Emphysema/chronic bronchitis	1.0	1.1	3.6	-0.6	-0.0	0.8	1.3	0.7	1.9	0.6	1.4	1.2
Medication: Blood pressure	1.0	1.8	4.0	2.0	0.0	-1.2	-1.4	-0.9	-1.4	-1.4	-1.7	-1.0
Arm predicted mass (right)	1.0	5.1	11.7	-0.2	-1.2	2.4	3.0	2.0	1.8	2.6	3.4	2.1
Overall health rating	1.0	2.1	4.7	-0.0	1.5	-1.1	-1.2	-2.2	-1.5	-1.7	-0.8	-1.8
Commuting to job workplace: Public transport	1.0	1.2	2.2	1.3	-1.1	-1.4	-1.2	-0.7	-0.8	-1.5	-0.8	0.2
High cholesterol (Self-reported)	1.0	1.7	3.5	1.2	-1.9	-1.5	-1.8	-0.4	-1.7	-0.5	-1.3	-0.2
Vascular/heart problems diagnosed by doctor	1.0	2.8	5.3	-2.0	-0.2	1.6	2.0	0.7	2.2	1.4	2.3	1.3
Alcohol drinker status: Previous	1.0	1.1	2.2	-1.4	1.1	-1.4	-1.1	-0.9	-0.1	-1.5	-0.7	-0.6
Alzheimer’s Disease (in father)	0.9	1.0	2.2	0.1	1.1	1.5	1.3	1.0	1.3	0.7	0.7	0.6
Financial difficulties in last 2 years	0.9	1.2	5.7	2.4	0.1	-0.8	-0.6	-1.0	-1.0	-1.2	-0.2	-0.8
Neuroticism score	0.9	1.8	3.8	-1.1	2.0	1.6	1.8	-0.3	0.9	0.9	1.8	-0.3
Alcohol intake versus 10 years previously	0.9	1.4	2.9	1.3	-0.4	1.1	1.4	1.1	0.2	1.5	1.7	1.1
Medication: Ibuprofen (e.g. Nurofen)	0.9	1.2	2.0	-1.2	1.0	1.4	1.4	0.6	1.1	1.2	1.1	0.1
Tense / ‘highly strung’	0.9	1.5	4.4	-0.3	2.1	1.5	1.9	0.4	0.8	0.8	1.1	-0.5
Blood clot in the leg (DVT)	0.9	1.1	3.0	-0.3	1.2	1.1	1.5	0.6	0.5	1.2	1.7	-0.4
Gout (self-reported)	0.9	1.3	3.6	0.7	-0.0	1.9	1.4	1.2	0.6	1.5	0.7	1.0
Arm fat-free mass (right)	0.9	4.5	10.8	-0.2	-1.1	2.2	2.8	1.8	1.8	2.3	3.3	2.1
Wheeze or whistling in the chest in last year	0.9	1.5	4.1	-0.3	-0.2	1.5	1.6	0.8	0.9	1.3	2.0	1.2
Shortness of breath walking on level ground	0.9	1.1	3.0	-1.7	0.6	0.8	1.2	-0.1	0.4	1.1	1.7	-0.1
Medication: Omeprazole	0.9	1.1	2.5	1.6	0.7	-0.7	-0.6	-1.4	-0.9	-1.5	-0.5	-0.8
Eye problems/disorders: Glaucoma	0.9	1.0	4.0	2.0	-1.9	-0.5	-0.4	0.4	-0.6	-0.1	-0.6	0.6
Arm fat-free mass (left)	0.9	4.8	11.8	-0.2	-1.0	2.4	2.9	1.8	1.9	2.4	3.4	2.0
Risk taking	0.9	1.4	2.3	0.9	-0.8	1.5	1.4	1.4	1.3	0.9	0.6	1.4
Bipolar Disorder or Schizophrenia	0.8	2.1	4.6	-2.0	-0.9	0.7	1.1	1.5	1.3	0.9	2.1	1.7
Lung FVC	0.8	4.2	8.6	0.5	0.7	-1.7	-2.3	-2.1	-2.9	-1.6	-2.3	-2.8
Angina	0.8	1.0	2.1	-1.2	1.5	1.1	0.9	0.5	1.0	0.6	1.2	0.2
Current tobacco smoking	0.8	1.4	3.4	0.1	0.1	1.5	1.4	1.3	1.8	0.7	0.9	1.3
Forced vital capacity (FVC)	0.8	3.2	6.1	1.6	-0.9	-1.8	-1.9	-1.9	-2.5	-1.6	-1.7	-1.9
Diabetes (self-reported)	0.8	1.2	6.0	2.5	-0.1	0.9	1.0	1.1	0.7	0.2	0.6	0.9
Depression (self-reported)	0.8	0.9	3.2	-0.9	1.8	-0.2	0.1	-1.2	0.1	-0.4	0.9	-1.5
Trunk predicted mass	0.8	4.4	11.5	-0.4	-0.5	2.5	2.9	1.6	1.9	2.2	3.4	1.7
Ever highly irritable/argumentative for 2 days	0.8	1.0	5.2	-1.1	2.3	0.3	0.6	-0.4	0.9	-0.5	0.3	-0.9
Mouth/teeth dental problems: Bleeding gums	0.8	1.1	2.2	-0.8	0.6	-1.2	-1.0	-1.4	-1.0	-1.0	-0.5	-1.5
Worry too long after embarrassment	0.8	1.4	4.6	-1.7	2.1	1.1	1.1	-0.7	0.6	0.6	1.0	-0.6
Number of self-reported non-cancer illnesses	0.8	1.5	5.2	1.9	-2.3	-0.9	-0.8	-0.1	-1.4	-0.1	-0.8	0.3
Schizophrenia (2018)	0.7	1.4	4.9	-0.9	-0.9	0.7	1.1	1.2	0.7	0.8	2.2	1.3
Alzheimer’s Disease (including proxy)	0.7	1.0	2.4	0.9	0.4	1.5	1.4	1.0	1.0	1.0	0.8	0.7
Blood Platelet Count	0.7	8.0	38.8	-1.6	6.2	-0.5	-0.0	-2.8	-1.0	-2.1	-0.2	-4.1
Neuroticism	0.7	1.6	3.1	-1.8	1.4	1.6	1.6	-0.1	1.2	0.9	1.4	0.3
Frequency of unenthusiasm / disinterest in last 2 weeks	0.7	0.9	2.4	0.5	1.0	1.0	1.6	0.1	1.3	0.2	1.4	0.3
Stomach or abdominal pain in last month	0.7	0.8	3.0	-1.7	0.4	-0.5	-0.2	-1.4	-1.0	-0.1	0.0	-1.0
Pain all over the body in last month	0.7	0.8	2.3	-1.5	0.3	0.6	0.6	0.4	1.3	0.1	1.1	1.0
Hayfever/allergic rhinitis (self-reported)	0.7	0.9	3.0	1.3	-1.7	0.3	0.8	0.6	0.2	0.7	0.9	1.0
Medication: Simvastatin	0.7	1.0	2.6	0.1	-1.6	-1.1	-1.4	-0.3	-1.0	-0.4	-1.4	-0.1
Trunk fat-free mass	0.7	4.2	11.2	-0.3	-0.6	2.4	2.8	1.5	1.8	2.1	3.3	1.7
Forced expiratory volume in 1-second (FEV1)	0.7	2.2	4.0	1.5	-1.5	-1.6	-1.5	-1.6	-2.0	-1.3	-1.1	-1.1
Medication: Lansoprazole	0.7	0.8	2.1	-1.1	-1.0	0.6	0.2	1.2	-0.2	1.5	0.5	0.8
Seen doctor (GP) for nerves, anxiety, tension or depression	0.7	1.0	3.1	-0.6	-0.5	1.1	1.2	0.6	0.9	1.0	1.8	0.7
Hair/balding pattern: Pattern 4	0.7	1.6	3.2	0.7	1.3	-1.1	-0.9	-1.8	-1.1	-1.3	-1.4	-1.4
Birth weight of first child	0.7	1.2	5.3	-2.3	0.3	0.7	0.9	-0.0	1.6	0.3	1.2	0.2
Loud music exposure frequency	0.7	0.8	3.3	-1.8	1.7	-0.0	-0.2	0.3	0.6	-0.2	-0.5	-0.4
Medication: Seretide 50 evohaler	0.7	0.8	1.7	-1.1	0.1	0.8	0.7	1.3	1.3	0.8	0.2	0.8
Handedness (chirality/laterality): Left-handed	0.7	0.9	1.9	-0.9	-1.1	0.8	0.7	0.9	0.5	1.4	0.9	1.1
Medication: Aspirin	0.7	1.0	2.2	-0.7	0.5	-1.0	-1.5	-0.5	-1.2	-0.4	-1.4	-1.0
Whole body water mass	0.7	3.8	10.9	-0.2	-0.2	2.3	2.8	1.2	1.6	1.9	3.3	1.5
Wears glasses or contact lenses	0.7	0.8	2.5	-0.0	-1.2	0.7	0.6	0.9	1.3	0.5	0.2	1.6
Worry (Nagel 2018)	0.6	1.2	2.9	-0.3	1.5	1.7	1.7	0.2	0.5	1.0	1.1	0.0
Crohns Disease (2017)	0.6	1.4	4.2	-2.0	1.1	-1.0	-1.3	-1.2	-1.0	-0.5	-0.7	-1.1
Irritable Bowel Disease (IBD)	0.6	1.3	3.1	-1.8	1.6	-1.1	-1.4	-0.8	-0.4	-0.8	-0.8	-1.0
Lupus	0.6	0.9	3.5	0.1	-0.7	0.8	0.9	1.4	-0.2	1.9	0.2	0.8
Primary Biliary Cirrhosis	0.6	0.9	2.6	1.6	-1.6	-0.6	-0.9	-0.2	-0.9	-0.7	-0.4	0.2
Sensitivity / hurt feelings	0.6	1.1	3.0	-0.0	1.7	1.5	1.5	-0.1	0.9	0.5	1.1	-0.4
Hand grip strength (right)	0.6	1.7	7.8	2.8	-2.2	0.1	0.2	0.3	-1.4	1.0	-0.1	0.1
Medication: Atenolol	0.6	0.7	3.6	1.9	-0.8	-0.4	-0.3	0.2	-1.0	0.1	-0.9	0.2
Hearing difficulty/problems with background noise	0.6	0.9	2.0	0.6	0.6	-0.9	-0.8	-1.4	-1.1	-0.8	-1.2	-1.0
Had other major operations	0.6	0.7	5.5	-2.4	0.0	-0.4	-0.5	0.5	0.4	0.3	-0.1	0.3
Heart attack	0.6	0.7	1.7	0.4	0.8	-0.8	-1.0	-0.8	-1.3	-0.9	-0.5	-1.0
Noisy workplace	0.6	0.7	2.5	0.7	1.3	-0.6	-0.2	-0.9	-0.3	-1.6	0.2	-0.9
Medication: Cholesterol lowering	0.6	1.0	3.1	1.8	-0.9	-0.8	-1.1	-0.1	-1.4	-0.4	-1.1	-0.2
Comparative body size at age 10	0.6	1.7	6.6	-0.0	2.6	-0.7	-0.5	-1.4	-0.5	-1.4	-1.0	-1.5
Migraine (self-reported)	0.6	0.8	3.4	-1.9	0.4	0.4	0.9	0.5	0.9	0.7	1.0	0.4
Comparative height size at age 10	0.6	3.4	15.0	0.2	-3.9	0.4	0.8	1.5	-0.1	2.1	1.9	2.1
Suffer from ‘nerves’	0.6	0.9	3.6	-0.6	1.9	1.3	1.1	-0.6	0.4	0.1	0.5	-0.5
Whole body fat-free mass	0.6	3.7	10.6	-0.2	-0.3	2.3	2.8	1.2	1.6	1.9	3.3	1.5
Smoking status: Current	0.6	1.0	3.0	0.2	0.3	1.2	1.2	1.1	1.7	0.4	0.7	1.1
Hearing aid user	0.6	0.7	3.3	-1.8	-0.4	0.4	0.3	0.9	0.5	0.8	0.8	0.7
Mother’s age at death	0.6	0.7	3.1	-1.8	1.1	0.2	0.2	0.4	1.2	0.1	-0.7	-0.0
Pain type(s) experienced in last month: Hip pain	0.6	0.8	3.3	-1.3	1.8	-0.1	-0.1	-0.7	-0.2	-0.4	-0.4	-1.1
Medication: Lisinopril	0.6	0.7	1.8	-0.6	0.1	-1.1	-1.4	-0.8	-0.6	-0.9	-1.0	-0.5
Basal metabolic rate	0.6	3.3	9.6	-0.0	-0.4	2.1	2.6	1.1	1.5	1.8	3.1	1.5
Number of operations (self-reported)	0.6	0.8	2.6	-0.1	-0.6	0.4	0.5	1.6	1.5	0.6	0.1	1.2
Irritability	0.6	1.1	2.4	-0.3	1.0	1.2	1.5	0.5	0.8	1.3	1.4	0.1
Age started oral contraceptive pill	0.6	0.7	2.1	-0.2	-1.1	-1.1	-1.5	-0.5	-0.9	-0.5	-0.8	-0.3
Heart attack/myocardial infarction (self-reported)	0.6	0.7	1.8	0.3	0.7	-0.8	-1.0	-0.8	-1.3	-0.8	-0.3	-1.0
Bipolar Disorder (2018)	0.5	0.8	3.1	-1.8	-0.3	0.4	0.4	1.0	1.2	0.3	0.6	1.1
Bipolar Disorder (2011)	0.5	0.5	1.1	0.0	0.0	0.0	-1.0	-0.8	-1.1	-0.6	-0.9	-0.7
Blood White Count	0.5	3.6	9.2	3.0	0.2	-1.9	-1.2	-2.1	-2.5	-2.2	-0.5	-1.4
BMI	0.5	3.1	6.3	-0.3	0.4	2.4	2.5	1.6	1.7	2.0	2.1	1.5
Waist Hip Ratio (WHR)	0.5	2.3	7.0	1.9	-2.1	-0.1	-0.9	0.7	-2.6	1.3	-1.4	0.6
Medication: Co-codamol	0.5	0.6	1.4	-0.1	-0.3	0.6	1.2	0.7	1.0	0.4	1.0	1.1
Diverticular disease/diverticulitis (self-reported)	0.5	0.6	1.9	0.5	-1.3	0.1	0.3	1.0	-0.5	1.4	0.3	0.5
Chronic bronchitis/emphysema (father)	0.5	0.6	1.9	0.2	0.1	-0.3	-0.6	-0.7	-1.4	0.2	-1.2	-0.8
Body mass index (BMI)	0.5	2.2	4.6	-0.3	0.8	1.9	2.1	1.0	1.1	1.6	2.1	1.0
Had menopause	0.5	0.6	1.5	-0.2	-1.0	-0.3	-0.7	1.2	0.2	0.4	-0.9	1.0
Weight	0.5	2.2	5.8	0.3	-0.6	1.7	2.0	1.1	0.9	1.8	2.4	1.3
Peak expiratory flow (PEF)	0.5	1.1	4.6	1.1	-2.1	0.4	0.8	0.6	0.1	0.7	0.9	1.1
Medication: Paracetamol	0.5	0.9	2.1	-1.1	0.7	1.0	1.3	0.2	1.5	0.4	1.2	0.4
Medication for cholesterol, blood pressure or diabetes	0.5	0.8	2.7	-1.6	0.1	0.7	0.9	0.2	1.1	0.6	1.2	0.5
High blood pressure (siblings)	0.5	0.7	3.4	1.2	-1.8	-0.2	-0.3	0.6	-0.2	0.4	-0.4	1.0
Exposure to tobacco smoke outside home	0.5	0.7	1.5	1.2	0.9	-0.7	-0.5	-0.7	-1.0	-0.8	-0.4	-0.8
Eye problems/disorders: None of the above	0.5	0.6	1.8	0.2	1.4	-0.0	-0.2	-0.9	-1.1	-0.4	0.2	-1.2
Neck or shoulder pain in last month	0.5	0.7	1.7	-0.5	0.5	0.9	1.1	0.7	0.6	1.0	1.3	0.2
Angina (self-reported)	0.5	0.7	1.7	-0.8	1.3	1.1	0.8	0.4	0.7	0.6	1.1	0.1
Leg fat-free mass (right)	0.5	2.6	8.4	-0.1	0.4	1.9	2.5	0.7	1.3	1.3	2.9	1.0
Long-standing illness, disability or infirmity	0.5	0.7	1.7	0.1	-0.6	1.1	1.1	0.4	0.7	0.6	1.3	1.0
Diabetes diagnosed by doctor	0.5	0.8	4.6	2.1	0.1	0.7	0.9	0.8	0.3	0.3	0.6	0.6
Breast cancer (self-reported)	0.5	0.5	1.2	-1.1	-0.2	0.9	0.9	0.2	0.5	1.0	0.7	0.3
Asthma (self-reported)	0.5	1.0	1.4	-0.0	-1.1	0.8	1.2	1.0	0.7	1.2	1.1	1.1
Diastolic blood pressure, automated reading	0.5	1.5	5.0	1.5	-2.2	0.3	0.6	1.3	0.3	1.0	0.6	1.6
Commuting to job workplace: Cycle	0.5	0.6	1.4	1.2	0.4	-1.0	-0.7	-0.5	-0.2	-1.2	-0.7	-0.1
Myopia	0.5	0.7	2.1	1.1	-1.4	0.0	0.2	0.9	-0.0	1.0	0.2	0.9
Supplements: Calcium	0.5	0.6	1.5	0.9	-1.2	-0.5	-0.6	1.0	-0.5	0.6	-0.8	0.3
Intelligence (Savage-Jansen 2018)	0.4	1.4	4.7	0.1	-2.2	-1.6	-1.2	-1.1	-1.5	-0.3	-0.4	-0.2
Major Depression (MDD)	0.4	0.5	2.0	-1.4	-1.2	-0.4	-0.2	-0.4	-0.5	0.3	0.5	0.3
Verbal and Numeric Reasoning (VNR)	0.4	0.9	2.5	-0.2	-1.2	-1.1	-1.0	-1.0	-1.6	-0.1	-0.4	-0.6
Lung FEV1/FVC ratio	0.4	2.1	9.5	0.9	-3.1	0.3	0.6	0.8	0.5	1.1	1.3	2.1
Chronotype (morning person)	0.4	0.9	1.5	1.0	0.8	-0.8	-0.9	-0.5	-1.2	-0.8	-1.0	-1.2
Hand grip strength (left)	0.4	1.1	5.8	2.4	-1.0	0.6	0.8	0.6	-0.6	1.2	0.2	0.1
Ever had hysterectomy (womb removed)	0.4	0.5	1.1	-0.2	0.1	-1.1	-0.9	-0.7	-0.8	-0.5	-0.3	-0.9
Systolic blood pressure, automated reading	0.4	1.3	3.9	0.6	-0.1	-1.1	-1.2	-1.1	-1.3	-1.0	-2.0	-0.6
Vitamin and mineral supplements	0.4	0.6	2.5	-0.2	-0.5	0.5	0.9	0.3	0.4	0.8	1.6	0.6
Medication: Metformin	0.4	0.6	4.3	2.1	-0.5	-0.0	0.0	0.4	-0.4	-0.3	-0.1	0.4
Pack years adult smoking proportion	0.4	0.6	1.4	-0.5	1.1	0.9	1.2	0.5	0.9	0.4	0.7	0.1
Leg fat-free mass (left)	0.4	2.2	7.2	0.2	0.3	1.9	2.3	0.6	1.0	1.3	2.7	0.9
Average weekly fortified wine intake	0.4	0.5	1.4	1.2	-0.9	0.3	0.0	0.8	0.2	0.3	-0.8	0.8
Fed-up feelings	0.4	0.7	3.3	-0.8	1.8	0.2	0.2	-0.7	0.0	-0.0	0.4	-1.1
Hayfever, allergic rhinitis or eczema	0.4	0.9	1.9	0.6	0.1	-1.3	-1.0	-1.0	-0.9	-0.9	-1.4	-0.9
Sitting height	0.4	2.9	8.1	-0.4	-2.9	0.7	1.4	1.0	1.4	1.7	2.5	1.9
Leg predicted mass (left)	0.4	2.3	7.5	0.0	0.3	1.9	2.3	0.6	1.0	1.4	2.7	0.9
Hip circumference	0.4	1.9	5.3	0.3	-0.4	1.6	2.1	0.6	1.4	1.0	2.3	1.2
Frequency of tiredness / lethargy in last 2 weeks	0.4	0.7	1.7	1.0	0.6	-0.4	-0.2	-1.3	-1.0	-0.8	-0.0	-1.0
Qualifications: A levels/AS levels or equivalent	0.4	0.8	2.2	0.4	-1.5	0.7	0.8	0.8	0.6	1.0	0.9	0.9
Arm fat mass (right)	0.4	1.8	4.0	-0.2	0.2	1.7	1.9	1.1	0.8	1.6	2.0	1.0
Exposure to tobacco smoke at home	0.4	0.4	1.0	0.8	0.4	-0.6	-0.4	-0.5	-1.0	-0.3	-0.7	-0.6
Number of children fathered	0.4	0.5	1.4	0.7	1.2	0.8	0.7	-0.1	0.9	-0.5	0.3	-0.1
Medication for pain relief, constipation, heartburn	0.4	0.7	2.6	0.5	-1.6	0.4	0.3	0.7	0.8	0.2	0.4	1.4
Heart disease (mother)	0.4	0.5	2.3	1.1	-1.5	-0.5	-0.4	0.4	-0.5	0.3	-0.1	0.7
Leg fat mass (right)	0.4	1.7	3.9	0.1	-0.9	1.4	1.6	1.2	0.6	2.0	1.5	1.3
Number of full sisters	0.4	0.5	1.3	0.6	-0.7	0.6	0.4	0.7	-0.6	0.9	1.1	0.4
Illness, injury, bereavement, stress in last 2 years	0.4	0.5	1.0	-0.6	0.1	-1.0	-0.9	-0.3	-0.5	-0.7	-1.0	-0.5
Smoking status: Previous	0.4	0.6	2.8	-1.7	0.5	-0.2	-0.8	0.1	0.0	0.4	-1.2	-0.7
Ever had bowel cancer screening	0.4	0.5	1.2	-0.6	-0.5	1.0	0.4	0.7	0.3	0.9	0.3	1.1
Eye problems/disorders: Cataract	0.4	0.4	2.0	-1.4	-0.5	-0.0	0.1	0.1	1.2	0.2	-0.1	0.5
Back pain experienced in last month	0.4	0.6	1.3	-0.8	0.1	0.9	0.8	0.8	0.2	1.1	1.1	-0.0
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.4	0.8	3.2	-1.8	-0.8	-1.0	-1.1	-0.7	-0.9	-0.2	0.1	-0.6
Leg predicted mass (right)	0.4	2.4	7.7	-0.1	0.5	1.9	2.4	0.6	1.2	1.2	2.8	0.9
Ever taken oral contraceptive pill	0.4	0.4	1.4	-0.7	0.0	-0.5	-0.6	-1.2	-0.6	-0.4	-0.3	-0.7
Medication: Omeprazole (e.g. Zanprol)	0.4	0.5	1.5	1.2	-0.4	-0.5	-0.3	-0.9	-0.9	-0.8	0.0	-0.1
Leg fat mass (left)	0.4	1.7	3.7	0.0	-0.9	1.4	1.7	1.3	0.7	1.9	1.6	1.4
Depression (Nagel 2018)	0.3	0.5	1.4	-0.6	0.8	0.4	0.7	-0.4	1.1	-0.1	1.2	0.2
Ulcerative Colitis (UC)	0.3	0.6	3.0	-0.6	1.7	-0.4	-0.6	-0.0	0.2	-0.6	-0.5	-0.6
Reaction Time	0.3	0.6	1.7	-1.3	-0.6	0.4	0.5	0.7	0.6	0.5	0.9	0.8
Triglycerides	0.3	0.6	2.3	1.3	0.1	-0.2	-0.8	0.5	-0.4	0.1	-1.5	-0.3
Hypothyroidism (self reported)	0.3	0.7	2.8	-0.0	-0.5	-0.9	-0.8	-1.0	-1.7	-0.3	-0.3	-0.8
Relative age voice broke	0.3	0.5	3.6	1.9	-0.4	0.1	-0.2	-0.0	-0.3	-0.1	-0.6	-0.2
Bilateral oophorectomy (both ovaries removed)	0.3	0.3	1.6	-0.0	-0.4	-0.0	0.5	-0.8	0.5	-0.1	1.2	0.0
Past tobacco smoking	0.3	0.5	2.1	1.4	-0.2	0.0	0.6	-0.4	-0.5	-0.4	1.0	0.3
Alcohol usually taken with meals	0.3	0.5	2.7	-0.8	-1.6	-0.1	-0.7	-0.0	-0.2	0.7	-0.8	0.1
Nervous feelings	0.3	0.6	1.4	-1.0	1.2	0.8	0.8	-0.7	-0.2	0.6	0.3	-0.6
Time employed in main current job	0.3	0.4	1.6	0.6	-0.5	-0.6	-0.5	-0.2	-1.3	-0.0	-0.7	-0.3
Happiness	0.3	0.4	1.1	-1.1	0.0	-0.6	-0.3	-0.7	-0.8	0.2	0.8	-0.6
Birth weight	0.3	0.5	2.1	-1.4	0.3	0.5	0.4	0.4	0.9	0.6	0.9	0.4
Leg fat percentage (right)	0.3	1.1	2.7	0.3	-1.2	0.9	1.0	1.2	0.3	1.6	0.7	1.2
Health satisfaction	0.3	0.4	1.0	-0.5	-1.0	-0.0	-0.0	-0.2	-0.7	0.7	1.0	0.4
Mouth/teeth dental problems: Loose teeth	0.3	0.3	1.0	-1.0	-0.4	0.2	0.2	-0.3	-0.7	1.0	0.2	-0.3
Mean time to correctly identify matches	0.3	0.7	1.5	-1.2	-0.4	0.8	0.7	0.7	0.6	1.0	0.8	0.8
Whole body fat mass	0.3	1.2	3.0	0.1	-0.9	1.1	1.3	0.9	0.1	1.7	1.5	1.0
Had major operations	0.3	0.4	1.9	0.1	1.4	0.6	0.1	0.5	0.7	0.1	-0.2	-0.5
Qualifications: NVQ or HND or HNC or equivalent	0.3	0.4	0.8	0.5	-0.3	-0.9	-0.3	-0.9	-0.7	-0.6	0.0	-0.6
Knee pain experienced in last month	0.3	0.5	1.4	0.9	0.7	-0.5	-0.0	-0.8	0.0	-1.2	0.4	-0.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.3	0.3	0.9	1.0	-0.8	0.4	0.5	0.1	0.2	0.2	0.6	0.6
Osteoarthritis (self-reported)	0.3	0.5	1.8	-1.1	1.4	-0.2	0.0	-0.6	-0.3	-0.4	-0.1	-0.5
Arm fat mass (left)	0.3	1.1	2.7	-0.1	0.3	1.3	1.5	0.7	0.4	1.4	1.6	0.6
Average weekly champagne plus white wine intake	0.3	0.4	2.1	-0.5	1.4	0.1	-0.1	-0.4	0.5	-0.3	-0.6	-0.9
Guilty feelings	0.3	0.4	1.3	-1.1	0.6	0.2	0.1	-1.1	0.1	0.1	0.8	-0.5
Ever smoked	0.3	0.5	2.1	-1.5	0.2	0.3	-0.2	0.6	1.0	0.5	-0.8	0.0
Leg fat percentage (left)	0.3	1.2	2.4	0.2	-1.3	0.9	1.1	1.3	0.5	1.6	0.9	1.3
Ever had prostate specific antigen (PSA) test	0.3	0.3	1.4	-0.2	0.3	0.7	0.6	0.3	1.2	0.2	-0.0	0.3
Schizophrenia vs Biploar Disorder	0.2	0.3	0.8	-0.2	-0.3	-0.5	-0.3	-0.7	-0.9	-0.2	0.7	-0.2
Breast Cancer	0.2	0.5	2.4	0.2	1.5	-0.2	0.0	-0.4	0.3	-0.8	-0.7	-1.0
Age at First Birth	0.2	0.3	0.9	0.5	0.9	-0.4	-0.2	-0.5	0.1	-0.8	-0.7	-0.5
Rheumatoid Arthritis	0.2	0.3	0.9	0.3	-0.2	-1.0	-0.6	-0.6	-0.5	-0.9	-0.0	0.0
Type 2 Diabetes (T2D) (2018)	0.2	0.4	2.6	1.6	-0.2	0.2	0.4	0.3	0.1	-0.1	0.1	0.5
Hair Pigment	0.2	5.7	11.8	-1.8	-3.0	1.2	1.6	2.7	2.8	1.6	2.4	3.4
Hearing difficulty/problems: Yes	0.2	0.3	1.1	-0.1	-1.0	0.2	0.3	-0.1	0.3	0.6	0.1	0.8
Relative age of first facial hair	0.2	0.5	2.6	1.6	0.0	-0.2	-0.5	-0.0	-0.9	-0.3	-0.7	-0.4
Ever used hormone-replacement therapy (HRT)	0.2	0.3	1.2	-0.7	0.1	-0.4	-0.2	-0.4	1.1	-0.7	0.1	0.3
Diabetes (mother)	0.2	0.2	0.8	-0.2	0.1	-0.3	-0.3	-0.6	-0.5	-0.5	-0.9	-0.2
Qualifications: CSEs or equivalent	0.2	0.3	1.4	0.4	1.2	0.5	0.3	-0.3	-0.3	-0.0	-0.1	-0.6
High blood pressure (mother)	0.2	0.3	1.2	1.1	0.6	-0.3	-0.5	-0.1	-0.7	-0.3	-0.4	-0.6
Trunk fat mass	0.2	1.0	2.3	0.5	-1.2	0.8	1.0	0.8	-0.2	1.5	1.2	1.0
Number of incorrect matches in round	0.2	0.3	1.0	-0.0	1.0	0.8	0.6	0.1	0.8	-0.0	0.3	-0.2
Allergy	0.2	0.5	1.3	-0.3	-0.7	0.8	0.4	1.1	0.7	0.6	0.5	0.9
Arm fat percentage (right)	0.2	0.6	1.3	0.1	0.8	1.2	1.1	0.5	0.2	1.0	1.0	0.4
Serious illness, injury or assault of a close relative in last 2 years	0.2	0.2	0.9	-0.9	-0.4	0.2	0.1	0.1	0.3	0.8	-0.4	-0.2
Asthma	0.2	0.4	1.1	0.1	-1.0	0.4	0.7	0.6	0.3	0.8	0.7	0.7
Prospective memory result	0.2	0.2	0.9	-0.6	0.6	-0.1	-0.3	0.2	-0.3	0.0	-0.9	-0.6
Lung cancer (father)	0.2	0.2	0.7	-0.1	0.2	-0.3	-0.2	0.5	0.6	-0.4	-0.9	0.1
Illnesses of mother	0.2	0.3	1.7	-1.3	0.3	0.1	0.4	-0.3	0.6	-0.1	0.5	-0.1
Standing height	0.2	1.6	10.0	1.2	-3.2	-0.2	0.2	0.6	-0.2	0.9	1.0	1.0
Breastfed as a baby	0.2	0.2	1.3	-1.1	-0.4	-0.0	0.0	0.0	0.3	0.5	0.3	0.2
Headache pain in last month	0.2	0.4	1.0	-1.0	-0.9	-0.5	-0.2	-0.8	-0.7	0.1	0.5	-0.2
Chronic bronchitis/emphysema (mother)	0.2	0.2	0.6	0.2	-0.5	-0.4	-0.5	-0.5	-0.2	-0.8	0.1	0.0
Body fat percentage	0.2	0.8	2.3	0.2	-1.0	0.7	0.7	1.0	-0.2	1.5	0.7	1.0
Age at first live birth	0.2	0.3	1.4	0.6	-1.2	-0.1	0.1	0.3	0.5	-0.3	-0.1	0.9
Alcohol intake frequency.	0.2	0.4	0.6	-0.7	0.5	0.7	0.8	0.8	0.4	0.6	0.7	0.7
Family relationship satisfaction	0.2	0.2	0.8	-0.0	0.5	-0.2	-0.5	-0.3	-0.6	0.2	0.1	-0.9
Commuting to job workplace: Car/motor vehicle	0.2	0.2	1.2	0.0	0.4	-0.2	-0.3	-0.4	-0.7	-0.1	0.0	-1.1
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.4	1.3	0.4	0.5	0.3	1.0	0.7	0.5	0.2	1.1	-0.1
Friendships satisfaction	0.2	0.2	0.6	-0.2	0.2	-0.4	-0.6	-0.3	-0.4	0.2	-0.5	-0.8
Commuting to job workplace: Walk	0.2	0.2	0.6	-0.6	-0.8	-0.2	-0.3	0.4	0.2	-0.1	-0.5	0.7
Supplements: Fish oil (including cod liver oil)	0.2	0.3	1.3	0.3	0.3	-0.4	-0.6	0.2	-0.2	-0.3	-1.2	-0.6
Illnesses of father: High blood pressure	0.2	0.3	1.3	-0.1	-1.2	-0.3	-0.4	0.5	-0.1	0.3	-0.4	0.5
Ever depressed for a whole week	0.2	0.2	0.6	-0.8	-0.1	0.3	0.5	-0.1	0.5	0.4	0.6	0.3
Pain experienced in last month	0.2	0.3	1.0	0.4	0.4	0.6	0.3	0.8	1.0	0.0	-0.2	0.6
Pack years of smoking	0.2	0.3	0.9	-0.5	1.0	0.6	0.8	0.0	0.4	0.1	0.4	-0.2
Body Mass Index (BMI) (2010)	0.1	0.2	0.4	0.1	-0.5	-0.1	-0.4	0.5	-0.6	0.6	-0.3	-0.4
Fasting Glucose	0.1	0.2	0.7	0.3	0.8	0.4	0.3	0.2	-0.1	0.1	-0.3	-0.4
HDL Cholesterol	0.1	0.2	0.8	0.6	0.2	-0.2	0.1	-0.9	-0.1	-0.8	-0.2	-0.3
Blood Eosinophil Count	0.1	0.8	1.6	-0.9	1.3	-0.0	0.1	-1.2	-0.7	-0.2	0.8	-1.2
Blood Red Count	0.1	1.3	6.1	2.5	0.7	0.3	1.4	-0.0	0.6	-0.7	1.5	0.6
Height	0.1	1.5	8.9	1.1	-3.0	-0.6	-0.2	-0.3	-0.3	-0.3	1.2	1.1
Smoking Status	0.1	0.2	1.3	-0.2	0.7	0.1	-0.3	0.3	0.2	0.1	-1.1	-0.4
Allergy or Eczema	0.1	0.3	1.1	1.1	-0.1	-0.6	-0.2	-0.5	-0.8	-0.0	-0.7	-0.3
Number of treatments/medications taken	0.1	0.1	0.6	0.0	-0.6	-0.1	-0.2	-0.3	-0.8	0.2	0.1	-0.0
Supplements: Zinc	0.1	0.1	0.4	-0.0	-0.3	-0.1	-0.2	0.5	-0.3	0.7	-0.6	-0.2
Diabetes (father)	0.1	0.1	0.3	0.5	-0.3	-0.3	-0.0	-0.5	-0.4	-0.2	0.5	0.2
Trunk fat percentage	0.1	0.6	1.6	0.5	-1.2	0.4	0.4	0.7	-0.6	1.3	0.5	0.8
Townsend deprivation index at recruitment	0.1	0.2	0.5	0.4	0.7	-0.2	0.2	-0.5	0.3	-0.6	-0.3	0.0
Maternal smoking around birth	0.1	0.2	0.7	-0.4	0.0	-0.3	-0.7	0.0	-0.8	0.1	-0.5	-0.5
Age when periods started (menarche)	0.1	0.3	0.9	0.3	0.7	0.1	-0.2	-0.9	-0.8	-0.4	0.0	-0.7
Medication: Levothyroxine sodium	0.1	0.2	0.8	0.7	-0.1	-0.1	-0.1	-0.0	-0.9	0.1	0.1	-0.1
Fluid intelligence score	0.1	0.2	0.8	-0.4	-0.8	-0.5	-0.4	-0.2	0.2	-0.1	-0.9	0.2
Illnesses of siblings	0.1	0.2	0.9	-0.2	0.5	0.1	-0.0	0.1	-0.7	0.3	0.2	-0.9
Hypothyroidism/myxoedema (self-reported)	0.1	0.2	1.2	0.2	-0.4	-0.3	-0.3	-0.3	-1.1	0.1	0.1	-0.2
Medication: Amlodipine	0.1	0.1	0.3	0.5	0.6	0.5	0.1	0.4	-0.1	0.3	-0.4	0.2
Chest pain or discomfort	0.1	0.2	0.8	-0.0	0.5	0.5	0.5	-0.4	-0.0	-0.1	0.9	-0.2
Arm fat percentage (left)	0.1	0.5	1.0	-0.1	0.7	0.9	0.9	0.5	0.0	1.0	0.8	0.2
Ever had stillbirth, spontaneous miscarriage or termination	0.1	0.1	0.4	-0.7	0.4	-0.4	-0.3	0.1	0.2	-0.2	-0.1	-0.5
Mineral and other dietary supplements	0.1	0.1	0.5	0.3	0.1	-0.1	0.4	-0.6	0.1	-0.2	0.7	0.1
Average weekly beer plus cider intake	0.1	0.2	0.7	-0.4	0.1	0.6	0.6	-0.2	0.3	0.2	0.8	0.5
Unable to work because of sickness or disability	0.1	0.1	0.3	0.3	0.1	-0.0	0.2	-0.5	-0.2	-0.4	0.5	-0.3
Heart disease (siblings)	0.1	0.1	0.4	-0.6	0.3	-0.1	-0.0	-0.2	0.6	-0.3	-0.2	0.3
Tanning	0.0	0.5	1.4	0.5	0.5	1.2	1.1	-0.2	0.8	0.4	0.9	0.1

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