TWAS hub - MPZL3

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Esophagus Muscularis	0.1430	0.0540	2.9e-03	-0.001	NA	0.027	NA	0.000	3.8e-01	NA	8.4e-03	NA	3.0e-01
2	GTEx	Pancreas	0.1670	0.0550	1.2e-03	0.165	NA	0.147	NA	0.058	1.7e-07	NA	9.1e-07	NA	1.9e-03
3	GTEx	Skin Sun Exposed Lower leg	0.0770	0.0340	9.9e-03	0.027	NA	0.032	NA	0.060	2.3e-03	NA	1.1e-03	NA	9.5e-06
4	GTEx	Thyroid	0.1800	0.0410	9.2e-08	0.160	NA	0.149	NA	0.158	2.8e-12	NA	1.7e-11	NA	3.7e-12
5	TCGA	Breast Invasive Carcinoma	0.0152	0.0085	1.1e-03	0.018	0.014	0.013	NA	0.012	1.2e-04	5.7e-04	9.9e-04	NA	1.2e-03
6	TCGA	Esophageal Carcinoma	0.0900	0.0500	4.5e-03	0.049	0.045	0.039	NA	0.030	1.1e-02	1.4e-02	2.2e-02	NA	3.9e-02
7	TCGA	Lung Adenocarcinoma	0.0644	0.0348	1.7e-04	0.015	0.017	0.022	NA	0.020	6.5e-03	3.9e-03	1.2e-03	NA	1.9e-03
8	TCGA	Prostate Adenocarcinoma	0.0783	0.0372	1.3e-06	0.077	0.067	0.065	NA	0.064	2.0e-08	1.5e-07	2.6e-07	NA	3.0e-07
9	TCGA	Stomach Adenocarcinoma	0.0670	0.0380	4.8e-04	0.064	0.027	0.044	NA	0.054	2.1e-05	4.5e-03	3.9e-04	NA	8.9e-05
10	TCGA	Thyroid Carcinoma	0.0570	0.0300	4.3e-05	0.065	0.053	0.047	NA	0.051	5.9e-07	6.2e-06	2.3e-05	NA	1.0e-05

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10
Blood clot in the leg (DVT)	6.3	8.1	12.0	-2.4	-3.1	-1.9	-3.5	-3.2	-2.7	-2.8	-2.9	-3.0	-2.7
Deep venous thrombosis (DVT) (self-reported)	6.0	7.7	11.2	-2.6	-3.1	-1.8	-3.3	-3.1	-2.6	-2.6	-2.7	-3.0	-2.6
Exposure to tobacco smoke outside home	5.4	7.3	14.2	-2.2	-3.4	-3.3	-2.8	-2.5	-3.1	-1.6	-1.9	-3.8	-1.1
Average weekly spirits intake	4.4	5.4	8.7	-1.8	-2.4	-1.1	-2.7	-3.0	-1.8	-2.8	-2.2	-2.2	-2.7
Ulcerative Colitis (UC)	4.3	8.1	16.2	-1.1	-3.1	-2.3	-3.3	-3.4	-2.1	-4.0	-2.5	-2.9	-2.7
Irritable Bowel Disease (IBD)	4.1	9.7	15.7	-2.1	-3.7	-2.7	-3.6	-3.5	-2.4	-4.0	-2.5	-3.5	-2.7
Townsend deprivation index at recruitment	3.8	5.4	13.0	-0.7	-3.0	-3.6	-1.7	-1.8	-3.2	-1.7	-0.8	-3.2	0.2
Commuting to job workplace: Walk	3.5	3.7	10.5	-0.6	-2.7	-3.2	-1.4	-1.0	-2.5	-1.4	-0.0	-2.8	0.6
Blood White Count	3.4	25.4	52.4	2.3	3.9	0.7	6.4	6.6	3.0	5.3	7.2	3.3	6.9
Medication: Amlodipine	3.4	4.8	11.4	0.1	2.0	1.5	2.3	3.0	1.9	3.4	2.2	1.8	2.1
Illnesses of father: Heart disease	3.2	4.4	7.5	-2.7	-2.4	-1.5	-2.6	-2.0	-1.9	-0.9	-2.2	-2.4	-1.5
Average weekly champagne plus white wine intake	3.0	4.1	9.0	-3.0	-2.3	-1.1	-2.1	-2.1	-2.5	-1.1	-1.8	-2.1	-1.2
Pulse wave Arterial Stiffness index	2.9	3.4	5.5	-2.3	-1.5	-1.2	-1.8	-2.3	-1.8	-1.4	-2.4	-1.4	-1.8
Seen doctor (GP) for nerves, anxiety, tension or depression	2.9	4.5	8.0	1.6	1.8	0.9	2.6	2.7	1.8	2.3	2.8	1.7	2.3
Exposure to tobacco smoke at home	2.8	3.1	5.4	-1.3	-2.3	-1.8	-2.1	-1.7	-2.2	-0.5	-1.3	-2.3	-1.3
Other serious medical condition/disability diagnosed by doctor	2.7	3.5	6.2	-0.1	-2.2	-2.5	-1.9	-2.0	-2.0	-1.8	-1.4	-2.4	-1.4
Crohns Disease (2017)	2.5	5.6	8.2	-2.3	-2.8	-2.1	-2.7	-2.3	-1.9	-2.9	-1.7	-2.7	-1.7
Medication: Levothyroxine sodium	2.5	4.2	9.3	1.7	2.6	3.0	1.5	1.4	3.1	1.1	0.6	2.8	-0.6
Hypothyroidism/myxoedema (self-reported)	2.5	5.0	9.5	3.1	2.6	2.9	1.7	1.5	2.9	1.8	0.7	2.7	-0.3
Pulse wave peak to peak time	2.5	2.9	5.1	2.2	1.3	1.1	1.7	2.2	1.6	1.2	2.3	1.3	1.8
Arm predicted mass (left)	2.4	12.0	19.9	-1.3	-4.1	-4.4	-3.2	-4.0	-4.5	-3.1	-2.4	-4.3	-1.4
Arm fat-free mass (left)	2.3	11.7	18.2	-1.2	-3.9	-4.2	-3.2	-4.1	-4.3	-3.3	-2.6	-4.1	-1.7
Weight	2.2	10.7	16.6	-1.9	-3.8	-3.5	-3.2	-3.7	-4.1	-3.5	-2.6	-3.8	-1.9
Illnesses of father: None of the above (group 1)	2.2	2.8	4.9	1.7	1.9	1.1	2.2	1.7	1.1	0.4	2.2	2.0	1.5
Fasting Glucose	2.1	2.6	5.2	-1.8	-2.0	-2.3	-1.7	-1.1	-1.6	-1.4	-0.9	-1.8	-0.6
Trunk fat-free mass	2.1	12.1	21.2	-1.2	-4.1	-4.6	-3.1	-4.0	-4.4	-3.5	-2.2	-4.3	-1.3
Comparative height size at age 10	2.1	11.3	17.3	-1.7	-3.5	-2.8	-4.0	-4.2	-2.7	-3.8	-3.6	-3.3	-3.5
Basal metabolic rate	2.1	11.5	20.2	-1.4	-4.1	-4.3	-3.0	-3.8	-4.5	-3.2	-2.1	-4.2	-1.2
Allergy or Eczema	2.0	5.2	8.5	0.4	2.7	1.2	2.9	2.7	2.3	1.9	2.7	2.7	2.0
Relative age voice broke	2.0	3.1	5.4	0.6	2.1	1.7	2.3	1.8	1.5	1.2	1.9	2.1	1.6
Arm fat mass (right)	2.0	8.2	11.6	-1.8	-3.3	-2.9	-3.0	-3.1	-3.4	-3.1	-2.3	-3.4	-1.9
Trunk predicted mass	2.0	11.6	20.2	-1.2	-4.0	-4.5	-3.0	-3.9	-4.4	-3.4	-2.1	-4.2	-1.3
Medication: Allopurinol	2.0	2.6	5.8	-0.4	-1.3	-0.6	-2.0	-2.2	-0.4	-2.4	-1.7	-1.2	-2.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	2.0	2.4	4.9	0.4	1.6	2.2	1.4	1.8	1.6	1.6	1.3	1.7	0.9
Tinnitus: Yes, but not now, but have in the past	1.9	2.0	4.5	-2.1	-1.7	-1.1	-1.2	-1.4	-2.0	-0.9	-0.8	-1.5	-0.7
Trunk fat mass	1.9	8.2	10.5	-1.8	-3.2	-2.5	-3.1	-3.1	-3.2	-3.2	-2.6	-3.2	-2.2
Whole body fat mass	1.9	7.9	10.7	-1.8	-3.1	-2.6	-3.0	-3.1	-3.3	-3.1	-2.5	-3.1	-2.1
Whole body fat-free mass	1.9	10.6	19.4	-1.4	-3.9	-4.2	-2.8	-3.6	-4.4	-3.0	-1.9	-4.0	-1.1
Whole body water mass	1.9	10.9	19.7	-1.3	-4.0	-4.4	-2.8	-3.6	-4.4	-3.0	-1.9	-4.1	-1.0
Arm fat mass (left)	1.9	7.7	12.2	-1.6	-3.4	-3.2	-2.8	-2.8	-3.5	-2.8	-2.0	-3.4	-1.4
Tinnitus: Yes, now most or all of the time	1.9	2.2	4.2	-0.3	-1.3	0.3	-1.7	-1.9	-2.0	-1.1	-2.0	-1.4	-1.4
Alcohol drinker status: Never	1.9	2.2	4.7	-1.5	-1.0	-0.5	-1.4	-1.9	-1.6	-2.2	-1.7	-0.9	-1.6
Tense / ‘highly strung’	1.8	2.9	4.0	1.2	1.9	1.7	1.9	1.9	1.8	1.5	2.0	1.8	1.1
Qualifications: NVQ or HND or HNC or equivalent	1.8	2.2	6.2	0.5	-1.9	-0.9	-1.5	-1.4	-2.5	-0.1	-1.5	-2.0	-0.5
Eye problems/disorders: Glaucoma	1.8	2.1	4.7	-0.4	-1.2	-1.0	-1.7	-1.7	-0.6	-2.2	-1.8	-1.1	-1.8
Hypothyroidism (self reported)	1.7	3.9	8.6	2.1	2.6	2.9	1.8	1.4	2.3	1.2	0.7	2.7	-0.0
Ever had hysterectomy (womb removed)	1.7	1.9	4.8	-1.9	-0.9	0.1	-1.7	-1.8	-0.4	-1.2	-1.4	-0.8	-2.2
Medication: Co-codamol	1.7	2.0	7.1	0.0	-1.1	-0.7	-1.4	-1.8	-1.3	-2.7	-1.4	-1.0	-1.3
Arm fat-free mass (right)	1.7	8.9	16.8	-1.6	-3.4	-4.0	-2.4	-3.4	-4.1	-2.8	-1.8	-3.6	-0.8
Arm predicted mass (right)	1.7	8.6	16.2	-1.6	-3.4	-3.7	-2.5	-3.4	-4.0	-2.7	-1.9	-3.6	-1.0
Basal cell carcinoma (self-reported)	1.7	2.0	4.9	1.5	-1.9	-2.2	-0.9	-0.4	-1.8	0.4	0.2	-2.1	0.7
Crohns Disease (2012)	1.6	2.5	4.9	-1.7	-2.0	-1.7	-1.5	-1.4	-1.7	-2.2	-0.3	-1.8	-0.3
Leg fat-free mass (left)	1.6	8.3	17.0	-1.7	-3.6	-3.7	-2.4	-3.0	-4.1	-2.5	-1.4	-3.6	-0.7
Leg predicted mass (left)	1.6	8.3	17.1	-1.7	-3.6	-3.8	-2.4	-3.0	-4.1	-2.5	-1.4	-3.6	-0.7
Number of live births	1.6	2.3	5.2	0.0	-0.9	0.3	-1.8	-2.1	-1.0	-1.8	-2.3	-0.9	-2.1
Commuting to job workplace: Car/motor vehicle	1.6	1.8	4.2	-0.9	2.0	1.9	0.6	0.6	1.8	1.0	-0.5	2.1	-0.9
Ulcerative Colitis	1.5	2.1	5.0	-0.0	-1.8	-2.1	-1.6	-1.4	-0.8	-2.2	-0.5	-1.6	-0.9
Waist circumference	1.5	5.5	8.9	-1.9	-2.6	-2.4	-2.3	-2.5	-3.0	-2.2	-2.0	-2.7	-1.4
Leg fat mass (right)	1.5	5.9	9.4	-2.1	-2.5	-2.3	-2.4	-2.7	-2.8	-3.1	-2.0	-2.4	-1.7
Smoking status: Previous	1.5	2.2	3.5	-0.9	-1.7	-1.4	-1.5	-1.7	-1.6	-1.9	-1.1	-1.7	-1.1
Friendships satisfaction	1.5	1.8	3.2	1.8	1.4	1.0	1.5	1.5	1.0	1.3	1.4	1.1	1.5
Past tobacco smoking	1.4	2.6	4.6	1.4	2.0	2.1	1.3	1.6	1.7	2.0	0.4	1.9	0.7
Leg fat-free mass (right)	1.4	7.3	16.2	-1.5	-3.4	-3.6	-2.1	-2.7	-4.0	-2.2	-1.2	-3.5	-0.4
Unable to work because of sickness or disability	1.4	1.8	5.9	-1.4	-1.4	-2.4	-0.9	-0.6	-1.1	-1.9	0.4	-1.4	0.2
Leg fat mass (left)	1.4	5.5	9.2	-2.1	-2.3	-2.0	-2.3	-2.6	-2.6	-3.0	-2.0	-2.3	-1.7
Depression (Nagel 2018)	1.3	2.0	3.3	1.7	1.7	1.8	1.3	1.0	1.8	1.3	1.0	1.6	0.1
Worry (Nagel 2018)	1.3	2.8	4.3	0.9	2.0	2.0	1.7	1.5	1.9	1.2	1.9	2.1	0.7
Age at First Birth	1.3	1.8	2.7	1.3	1.3	0.8	1.6	1.5	1.0	1.6	1.5	1.2	1.5
Smoking Status	1.3	3.1	6.4	-0.1	-2.3	-2.4	-1.7	-1.6	-1.7	-2.5	-0.4	-2.2	-0.7
Trunk fat percentage	1.3	5.2	7.2	-1.5	-2.5	-1.6	-2.7	-2.4	-2.3	-2.6	-2.4	-2.4	-2.1
Body mass index (BMI)	1.3	5.5	9.7	-1.8	-2.6	-2.7	-2.2	-2.5	-3.1	-2.2	-1.9	-2.8	-1.1
Qualifications: None of the above	1.3	2.8	4.8	0.8	1.6	0.8	2.1	2.2	1.2	1.9	2.1	1.4	1.8
Time employed in main current job	1.3	1.5	3.9	0.1	0.7	-0.7	1.2	1.8	0.6	2.0	1.3	0.5	1.8
Angina (self-reported)	1.3	1.7	5.9	-0.3	0.4	-0.8	1.5	1.5	-0.3	1.4	1.9	0.1	2.4
Forced expiratory volume in 1-second (FEV1), predicted	1.3	2.7	5.0	-0.4	-2.1	-1.3	-1.9	-1.8	-1.3	-2.2	-1.2	-1.9	-1.4
Leg predicted mass (right)	1.3	7.1	15.8	-1.5	-3.4	-3.5	-2.1	-2.7	-4.0	-2.1	-1.2	-3.4	-0.4
Alcohol drinker status: Previous	1.3	1.5	3.5	-1.9	1.1	0.8	1.1	1.6	0.8	1.1	1.3	1.2	1.0
Alzheimer’s Disease (in father)	1.2	1.3	2.1	1.4	1.2	0.3	1.4	1.4	0.8	-0.1	1.2	1.1	1.5
Bipolar Disorder (2011)	1.2	1.1	4.9	2.2	-0.8	-1.0	-1.2	-0.3	0.6	-0.8	-0.6	-1.0	-0.9
Rheumatoid Arthritis	1.2	1.6	13.1	3.6	0.2	-0.7	0.6	0.5	0.0	0.9	0.8	0.2	0.6
Schizophrenia (2014)	1.2	2.5	9.0	2.2	2.0	1.3	1.0	1.0	3.0	0.4	0.4	1.9	-0.4
Relative age of first facial hair	1.2	2.5	5.2	2.3	1.5	1.1	1.8	1.6	1.7	1.2	1.7	1.5	1.1
Arm fat percentage (right)	1.2	4.6	6.6	-1.5	-2.5	-1.9	-2.4	-2.1	-2.3	-2.6	-1.8	-2.4	-1.7
Hip circumference	1.2	5.1	10.2	-1.4	-2.8	-2.7	-2.1	-2.2	-3.2	-1.9	-1.6	-2.9	-0.8
Mouth/teeth dental problems: Dentures	1.2	1.9	3.6	1.9	1.2	-0.0	1.5	1.7	1.1	1.4	1.7	1.1	1.5
Peak expiratory flow (PEF)	1.2	2.7	4.5	-1.1	-1.8	-1.1	-1.7	-2.0	-1.8	-2.1	-1.5	-1.7	-1.2
Body fat percentage	1.2	4.6	6.6	-1.6	-2.2	-1.4	-2.5	-2.3	-2.1	-2.6	-2.3	-2.1	-2.1
Comparative body size at age 10	1.2	3.2	5.7	-1.3	-1.4	-1.1	-2.1	-2.3	-1.0	-2.0	-2.4	-1.4	-2.3
Eye problems/disorders: None of the above	1.2	1.4	4.9	0.3	0.6	1.1	1.2	1.1	-0.3	2.2	1.2	0.4	1.7
Emphysema/chronic bronchitis	1.2	1.3	4.0	-0.3	1.7	1.2	0.8	0.8	2.0	-0.6	0.3	1.7	-0.4
Pain type(s) experienced in last month: Hip pain	1.2	1.5	3.2	0.2	-0.8	-1.0	-1.2	-1.6	-1.4	-1.8	-1.4	-0.7	-1.2
Ever smoked	1.2	2.2	4.1	-1.7	-1.8	-2.0	-1.2	-1.4	-1.4	-1.6	-0.5	-1.7	-0.6
Prostate Cancer	1.1	1.5	3.9	0.3	-0.4	0.3	-1.4	-1.6	-0.2	-1.8	-1.8	-0.4	-2.0
LDL Cholesterol	1.1	1.8	5.9	-0.8	0.2	0.7	-1.2	-1.2	1.1	-1.7	-1.9	0.4	-2.4
Medication for hormone replacement therapy	1.1	1.2	4.1	-1.9	-1.2	-2.0	-0.4	-0.0	-0.8	-0.4	0.6	-1.2	0.4
Vitamin and mineral supplements	1.1	1.4	4.0	-1.9	-1.3	-1.1	-0.8	-1.0	-2.0	0.0	-0.6	-1.3	-0.1
High blood pressure (mother)	1.1	1.6	3.3	-0.2	-1.7	-0.9	-1.8	-1.2	-1.2	-0.3	-1.3	-1.7	-1.1
Mineral and other dietary supplements	1.1	1.5	5.2	-0.9	0.1	-1.4	1.1	1.4	-0.6	0.6	1.7	-0.1	2.3
Commuting to job workplace: Public transport	1.1	1.3	3.8	-1.6	-1.5	-0.8	-0.7	-1.1	-1.9	-0.4	-0.1	-1.4	0.2
Diastolic blood pressure, automated reading	1.1	3.3	6.9	-2.5	-1.6	-1.3	-2.1	-2.0	-1.4	-0.8	-2.6	-1.5	-1.7
Neuroticism (Nagel 2018)	1.0	2.3	5.1	0.6	2.0	2.2	1.5	1.3	1.6	1.4	1.2	1.9	0.4
Major Depression (MDD)	1.0	1.2	3.3	1.6	-0.6	-0.2	-1.4	-1.2	0.3	-0.2	-1.4	-0.7	-1.8
Reaction Time	1.0	1.9	4.4	-0.6	-1.6	-2.1	-0.4	-0.6	-1.7	-1.9	1.1	-1.6	0.8
Mean Putamen Volume	1.0	1.1	3.5	1.9	1.3	0.6	1.2	0.7	0.8	0.3	0.9	1.2	0.9
HbA1C	1.0	1.1	4.6	-2.1	-0.9	-1.1	-0.4	-1.1	-1.5	0.3	-0.8	-0.0	-0.5
BMI	1.0	5.8	15.7	-1.3	-2.9	-3.2	-1.9	-1.9	-4.0	-1.8	-1.0	-3.2	0.0
Angina	1.0	1.3	4.8	0.1	0.0	-1.0	1.2	1.3	-0.6	1.3	1.6	-0.2	2.2
Forced expiratory volume in 1-second (FEV1)	1.0	3.5	6.9	-0.6	-2.6	-2.3	-1.8	-1.6	-2.4	-1.8	-0.9	-2.6	-0.2
Birth weight of first child	1.0	1.8	3.4	-0.4	-1.8	-1.5	-1.2	-1.3	-1.7	-1.8	0.1	-1.7	-0.4
Pulse rate, automated reading	1.0	3.2	7.1	-1.9	-1.2	-1.4	-2.1	-2.2	-1.0	-2.7	-1.8	-1.0	-1.9
Illnesses of siblings: Diabetes	1.0	1.3	3.1	1.8	1.4	0.8	1.1	0.8	1.7	0.8	0.7	1.1	0.3
Myopia	1.0	1.5	7.1	-2.7	0.1	1.7	-0.7	-0.4	0.5	0.7	-1.1	0.0	-1.3
Bipolar Disorder or Schizophrenia	0.9	2.2	8.4	1.8	1.7	0.8	1.1	1.3	2.9	0.2	0.9	1.6	-0.1
Alzheimer’s Disease (including proxy)	0.9	1.3	2.5	0.6	1.3	1.1	1.5	1.6	0.7	0.4	0.9	1.2	1.5
Coronary Artery Disease (CAD)	0.9	1.1	2.5	0.4	-1.2	-0.5	-1.6	-1.0	-0.6	-0.9	-1.1	-1.5	-0.9
Average weekly fortified wine intake	0.9	1.0	2.3	-0.9	-1.2	-0.5	-1.2	-1.0	-1.5	-0.6	-1.2	-1.2	-0.2
Hayfever/allergic rhinitis (self-reported)	0.9	1.2	2.7	0.8	1.5	0.4	1.6	1.2	0.7	-0.5	1.1	1.6	1.0
Depression (self-reported)	0.9	1.0	2.4	-0.1	1.2	0.8	1.1	1.1	1.6	0.9	1.2	1.0	0.5
Prospective memory result	0.9	1.1	4.4	0.4	-1.1	-2.1	-0.9	-0.3	-1.4	-0.2	-0.2	-1.5	0.6
Forced expiratory volume in 1-second (FEV1), Best measure	0.9	2.9	5.7	-0.9	-2.4	-2.2	-1.7	-1.4	-2.1	-1.5	-0.9	-2.4	-0.1
Breastfed as a baby	0.9	1.1	2.2	1.5	-1.0	-0.7	-0.9	-1.3	-1.0	-0.8	-1.1	-1.1	-0.8
Glaucoma (self-reported)	0.9	1.0	3.8	-0.3	-0.4	-0.5	-1.0	-1.1	0.2	-1.9	-1.3	-0.2	-1.4
Medication: Ventolin 100micrograms inhaler	0.9	1.2	2.8	1.7	1.2	1.2	1.3	0.7	0.1	0.2	0.8	1.4	1.1
Forced vital capacity (FVC), Best measure	0.9	3.4	7.5	-0.9	-2.7	-2.7	-1.9	-1.5	-1.6	-1.5	-0.7	-2.7	-0.4
Supplements: Vitamin C	0.9	1.0	1.9	1.1	1.2	0.4	1.2	1.0	1.4	-1.0	0.8	1.1	0.7
Qualifications: nursing, teaching	0.9	1.4	3.3	-0.2	1.2	1.5	0.9	1.3	1.8	1.6	0.6	1.2	0.2
Medication: Gliclazide	0.9	1.0	4.2	0.6	1.0	0.6	0.8	1.3	2.1	0.4	0.7	1.0	0.4
Age started oral contraceptive pill	0.9	1.1	3.1	1.5	1.1	1.8	0.4	-0.1	1.0	1.0	-1.1	1.1	-0.7
Bipolar Disorder (2018)	0.8	1.2	4.2	1.9	1.0	0.4	0.5	0.9	2.1	-0.4	0.7	1.1	-0.3
Body Mass Index (BMI) (2010)	0.8	1.0	2.8	-0.5	-1.0	-1.1	-0.8	-1.2	-1.7	-1.3	-0.5	-1.0	-0.3
Systolic blood pressure, automated reading	0.8	2.3	7.7	-2.8	-1.1	-1.0	-1.7	-1.3	-0.5	-0.7	-2.1	-1.2	-1.3
Hand grip strength (right)	0.8	2.1	6.0	-0.1	-1.0	-1.2	-1.4	-2.4	-0.5	-2.3	-1.2	-0.9	-1.7
Sitting height	0.8	5.5	13.9	-0.8	-2.5	-2.4	-2.3	-2.8	-2.4	-3.7	-1.6	-2.2	-1.6
Frequency of tenseness / restlessness in last 2 weeks	0.8	1.2	2.6	-0.4	1.4	0.1	1.6	1.1	1.1	0.1	1.5	1.2	0.9
Forced vital capacity (FVC)	0.8	3.2	6.9	-0.9	-2.6	-2.3	-1.9	-1.5	-1.8	-1.5	-1.0	-2.6	-0.6
Serious illness, injury or assault of a close relative in last 2 years	0.8	0.9	2.6	-1.6	-0.5	-0.8	-0.7	-1.1	-0.1	-0.9	-1.1	-0.8	-1.1
Standing height	0.8	8.2	12.8	-0.7	-3.4	-2.6	-3.1	-3.6	-2.9	-3.2	-2.4	-3.2	-2.3
Loud music exposure frequency	0.8	0.9	1.8	1.0	-1.3	-1.1	-1.0	-0.8	-1.2	-0.5	-0.3	-1.3	-0.2
Leg fat percentage (right)	0.8	2.8	5.6	-1.5	-1.3	-0.9	-1.8	-1.9	-1.3	-2.4	-2.0	-1.3	-1.9
Mouth/teeth dental problems: Loose teeth	0.8	1.0	3.1	0.9	-1.1	-1.8	-0.8	-1.2	-0.5	-0.9	-0.2	-1.1	-0.8
Overall health rating	0.8	1.8	3.9	-0.6	-1.2	-0.9	-1.6	-1.6	-0.9	-2.0	-1.2	-1.1	-1.7
Arm fat percentage (left)	0.8	3.3	4.8	-1.4	-2.2	-1.9	-1.9	-1.6	-2.2	-2.2	-1.2	-2.1	-1.1
Supplements: Fish oil (including cod liver oil)	0.8	1.0	3.3	0.5	0.4	1.6	-0.6	-1.0	0.5	-0.7	-1.2	0.7	-1.8
Medication: Atorvastatin	0.8	1.0	2.7	-1.1	-1.5	-1.3	-1.0	-0.5	-1.1	0.0	-0.5	-1.6	-0.2
Verbal and Numeric Reasoning (VNR)	0.7	1.6	3.5	-0.7	-1.3	-0.2	-1.8	-1.4	-0.8	-1.1	-1.6	-1.1	-1.9
Lupus	0.7	1.0	2.6	0.6	1.2	1.3	0.8	0.7	1.1	1.6	-0.6	1.4	0.0
Waist Hip Ratio (WHR)	0.7	3.2	4.5	-1.3	-2.1	-1.6	-2.1	-1.9	-1.4	-2.0	-1.5	-2.1	-1.8
Systolic Blood Pressure	0.7	3.4	10.3	-3.2	-2.1	-2.0	-1.9	-1.2	-1.4	-0.5	-1.6	-2.3	-0.8
Severe depression (siblings)	0.7	0.8	2.9	0.6	0.5	-0.8	0.9	0.9	1.3	0.0	1.7	0.2	0.9
Qualifications: CSEs or equivalent	0.7	0.9	2.5	-0.3	-1.3	-1.6	-0.7	-0.6	-1.3	-1.0	-0.0	-1.2	0.4
Diverticular disease/diverticulitis (self-reported)	0.7	0.8	3.5	-0.4	0.4	-0.3	0.8	1.0	0.5	1.9	0.7	0.1	1.3
Had other major operations	0.7	0.8	5.8	-2.4	0.4	0.6	-0.2	-0.0	0.8	0.1	-0.5	0.4	-0.9
Father’s age at death	0.7	0.9	3.2	0.9	1.0	1.7	0.7	0.5	0.2	1.8	-0.1	0.7	0.3
Lung cancer (father)	0.7	0.8	3.4	-0.0	-0.2	-0.7	0.9	0.4	-1.3	0.3	1.2	-0.3	1.8
Illnesses of mother	0.7	0.9	2.2	-0.1	-1.0	-1.1	-0.9	-1.2	-1.2	-1.5	-0.6	-0.7	-0.5
Pulse wave reflection index	0.7	0.9	1.9	-0.8	1.1	0.8	1.4	0.8	0.5	1.1	0.8	1.1	0.8
Chronic bronchitis/emphysema (mother)	0.7	0.9	2.3	-0.1	1.4	0.8	1.3	0.8	0.9	-0.4	0.6	1.5	0.3
Medication: Ibuprofen	0.7	0.8	3.3	1.8	0.7	1.6	-0.1	-0.1	0.9	-0.0	-0.5	0.7	-0.7
Age at last live birth	0.7	1.0	3.1	1.6	1.1	1.0	0.5	0.6	1.8	0.8	0.1	1.1	-0.2
Knee pain experienced in last month	0.7	1.1	4.1	-2.0	0.4	1.2	-0.5	-0.8	-0.2	-0.7	-1.5	0.4	-1.4
Average weekly red wine intake	0.7	1.0	2.5	-1.5	-0.8	0.2	-1.1	-1.2	-1.6	-0.6	-1.1	-0.7	-0.7
Osteoarthritis (self-reported)	0.7	0.9	3.5	0.8	-0.1	1.1	-0.9	-0.8	0.4	-1.1	-0.8	0.0	-1.9
Number of self-reported non-cancer illnesses	0.7	1.2	2.5	0.2	1.1	0.3	1.4	1.6	1.2	-0.1	1.5	1.2	0.8
Ever taken oral contraceptive pill	0.7	0.8	3.0	0.5	-1.4	-1.7	-0.5	-0.3	-0.7	-0.4	0.4	-1.4	0.2
Medication: Omeprazole (e.g. Zanprol)	0.7	0.8	3.6	1.9	1.1	0.5	0.7	0.6	1.0	0.7	0.4	0.9	-0.0
Depressed Affect (Nagel 2018)	0.6	1.2	3.1	0.9	1.4	1.8	0.9	0.8	1.1	1.2	0.6	1.3	0.1
Schizophrenia (2018)	0.6	1.1	4.2	0.8	1.4	0.7	1.0	0.9	2.1	0.6	0.7	1.2	0.1
Triglycerides	0.6	1.0	3.2	-1.8	-0.2	0.2	-1.0	-0.9	0.4	-0.4	-1.3	-0.3	-1.7
Diabetes (mother)	0.6	0.7	1.7	-1.3	0.9	1.2	0.5	0.5	1.3	0.7	-0.2	0.8	-0.3
Serious illness, injury or assault to yourself	0.6	0.7	2.1	-0.3	0.4	-0.9	0.9	0.9	0.2	0.4	1.3	0.2	1.5
Had menopause	0.6	0.7	2.4	-0.4	1.1	1.5	0.3	0.1	1.1	0.2	-0.5	1.2	-0.8
Medication: Ramipril	0.6	0.7	3.7	-1.9	-0.4	-0.6	-0.3	-0.4	-0.3	-1.6	0.4	-0.6	0.0
Qualifications: O levels/GCSEs or equivalent	0.6	1.0	3.5	0.2	-0.9	-1.9	-0.5	-0.7	-1.0	-1.8	0.4	-0.8	0.2
High blood pressure (siblings)	0.6	0.8	2.4	-0.4	-1.5	-0.7	-1.0	-0.7	-0.8	0.4	-0.3	-1.5	-0.6
Age at first live birth	0.6	1.1	4.7	2.2	0.9	0.8	0.7	0.6	1.2	0.9	0.4	1.0	0.4
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.6	0.7	1.5	0.2	0.9	0.6	1.2	1.0	0.6	0.4	1.2	0.9	1.0
Number of full sisters	0.6	0.8	2.3	0.1	-0.6	-1.1	0.6	0.7	-0.9	0.6	1.2	-0.6	1.5
Suffer from ‘nerves’	0.6	0.9	4.0	-2.0	-0.4	0.4	-0.7	-0.8	-0.0	-1.6	-0.5	-0.3	-1.1
Had major operations	0.6	0.7	2.6	1.0	1.0	0.4	0.7	0.9	1.6	0.7	0.5	0.8	0.1
Family relationship satisfaction	0.6	0.8	1.8	0.8	1.2	1.1	0.5	0.4	1.4	-0.6	0.4	1.2	-0.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.6	0.7	1.6	0.4	0.8	-0.0	1.0	1.2	0.8	-0.0	1.3	0.7	0.9
Eye problems/disorders: Cataract	0.6	0.7	2.3	-0.5	0.6	-0.2	-0.3	-0.6	0.7	-1.5	-1.3	0.6	-1.0
Osteoporosis (self-reported)	0.6	0.7	2.2	1.4	1.1	0.5	0.4	0.6	1.5	0.2	-0.1	0.9	-0.1
Hearing aid user	0.6	0.6	1.9	0.5	1.3	1.1	0.8	0.4	0.7	0.3	0.2	1.4	-0.2
Mother’s age at death	0.6	0.7	2.1	1.1	0.8	1.4	-0.0	-0.2	1.4	0.1	-0.5	0.7	-1.0
Financial situation satisfaction	0.6	0.8	3.2	0.1	-1.5	-0.8	-0.8	-0.7	-0.9	-0.1	0.1	-1.8	0.0
Illnesses of father: High blood pressure	0.6	0.7	1.7	-0.6	-0.9	0.3	-1.3	-0.7	0.2	0.4	-1.1	-0.9	-1.3
Leg fat percentage (left)	0.6	2.2	4.5	-1.6	-1.0	-0.6	-1.5	-1.7	-1.1	-2.1	-1.8	-1.0	-1.7
Ever had prostate specific antigen (PSA) test	0.6	0.7	2.0	0.0	1.2	1.0	0.6	0.1	1.4	0.5	-0.5	1.3	-0.5
Ever depressed for a whole week	0.6	0.7	1.2	0.6	1.1	0.5	1.1	0.9	0.8	0.8	0.9	0.9	0.8
Heart disease (siblings)	0.6	0.7	1.4	-0.7	0.9	1.2	1.1	0.8	0.8	0.9	0.6	0.8	0.3
Blood Red Count	0.5	4.8	17.4	-2.6	-0.8	-1.2	-2.2	-1.9	0.5	-4.2	-1.5	-0.6	-3.1
Number of treatments/medications taken	0.5	1.0	2.3	0.7	1.0	0.0	1.1	1.2	1.4	0.4	1.5	0.9	0.5
Ever used hormone-replacement therapy (HRT)	0.5	0.6	5.7	-2.4	0.1	0.4	0.0	-0.1	-0.3	0.7	0.1	0.1	-0.2
Bilateral oophorectomy (both ovaries removed)	0.5	0.6	2.3	-1.5	-0.7	0.5	-0.9	-0.6	-0.5	-0.2	-0.6	-0.5	-0.9
Multivitamins +/- minerals	0.5	0.6	2.5	1.6	0.2	0.6	-0.1	0.4	1.3	0.8	0.0	0.2	-0.4
Supplements: Glucosamine	0.5	0.7	2.4	0.9	0.1	1.5	-0.6	-0.8	0.1	0.3	-1.1	0.2	-1.2
Medication: Ibuprofen (e.g. Nurofen)	0.5	0.7	2.7	1.6	0.7	1.3	0.5	0.5	0.8	0.4	0.3	0.7	0.3
Impedance of arm (left)	0.5	2.3	4.5	0.9	1.4	2.1	1.1	2.1	2.0	1.0	1.2	1.7	0.5
Length of working week for main job	0.5	0.6	1.7	-1.3	-0.6	-0.8	-0.4	-0.7	-1.0	-0.9	-0.7	-0.4	-0.3
Mouth/teeth dental problems: Bleeding gums	0.5	0.7	3.5	-0.3	-0.7	-1.9	0.1	0.2	-0.6	-0.4	0.9	-0.6	0.9
Shortness of breath walking on level ground	0.5	0.6	2.3	-0.1	0.1	-0.9	0.8	0.9	-0.5	0.4	1.2	-0.1	1.5
Medication: Omeprazole	0.5	0.6	3.2	1.8	0.9	0.6	0.5	0.4	0.5	0.8	0.0	0.7	0.0
Mean time to correctly identify matches	0.5	1.0	3.5	-0.3	-1.1	-1.2	-0.4	-0.9	-1.2	-1.9	0.5	-1.0	0.1
Chest pain or discomfort	0.5	0.8	1.8	0.3	0.3	-0.2	1.1	1.3	0.1	0.9	1.3	0.1	1.3
Back pain experienced in last month	0.5	0.8	1.6	0.8	1.0	1.0	0.2	-0.2	1.1	-1.3	-0.4	0.9	-1.1
Wears glasses or contact lenses	0.5	0.6	2.3	0.3	1.0	1.5	0.2	0.7	1.0	0.4	0.2	0.9	-0.3
Number of operations (self-reported)	0.5	0.7	2.1	-1.2	0.5	1.2	0.2	0.4	1.1	1.4	0.0	0.6	-0.6
Fractured/broken bones in last 5 years	0.5	0.7	2.0	0.1	1.4	0.7	1.1	0.3	0.3	-0.5	0.5	1.4	0.5
Commuting to job workplace: Cycle	0.5	0.6	2.1	1.0	0.6	0.8	0.8	0.4	0.8	1.4	0.4	0.5	0.4
Schizophrenia vs Biploar Disorder	0.4	0.5	1.0	-0.4	1.0	1.0	0.7	-0.1	0.5	0.8	-0.7	0.9	-0.2
Primary Biliary Cirrhosis	0.4	0.6	3.5	1.9	-0.4	-1.1	0.1	-0.0	-0.0	-0.7	0.8	-0.3	0.4
Type 2 Diabetes (T2D) (2012)	0.4	0.5	2.0	-1.4	0.3	0.0	-0.2	-0.0	1.0	-1.2	-0.1	0.4	-0.5
Blood Platelet Count	0.4	5.2	10.8	-0.6	3.2	2.4	2.8	2.3	2.1	0.7	1.6	3.3	1.9
Heel T-Score	0.4	3.2	10.5	-0.2	-1.8	-2.4	-0.7	-1.7	-2.2	-3.2	-0.6	-1.9	-0.1
Type 2 Diabetes (T2D) (2018)	0.4	0.7	3.8	-0.2	-0.5	-2.0	-0.1	0.5	0.0	-1.1	0.2	-0.7	0.7
Frequency of depressed mood in last 2 weeks	0.4	0.5	1.1	0.3	1.0	0.9	0.5	0.1	1.1	0.8	0.1	0.9	-0.5
Eye problems/disorders: Diabetes related eye disease	0.4	0.4	1.9	-0.7	-0.0	-1.4	0.1	0.4	0.9	-0.8	0.5	0.1	0.1
Medication: Metformin	0.4	0.5	2.6	0.3	0.8	0.3	0.2	0.6	1.6	-0.9	-0.1	0.7	-0.4
Pack years adult smoking proportion	0.4	0.6	1.0	-0.9	-0.6	-0.0	-1.0	-1.0	-0.6	-0.5	-0.8	-0.6	-1.0
Taking other prescription medications	0.4	0.7	3.3	0.6	0.9	0.7	0.5	0.5	1.8	0.5	0.5	0.8	-0.4
Alcohol usually taken with meals	0.4	0.7	2.6	-1.6	0.3	0.2	0.7	0.9	-0.3	0.5	0.8	0.2	1.4
Pain all over the body in last month	0.4	0.4	1.3	-0.2	-0.4	0.5	-0.7	-0.3	0.5	-1.0	-0.4	-0.3	-1.1
Happiness	0.4	0.4	1.3	-0.5	0.1	1.1	-0.4	-0.7	-0.1	-0.9	-0.8	0.2	-0.7
Headache pain in last month	0.4	0.6	1.7	1.3	0.4	-0.5	0.8	0.8	-0.3	0.5	0.9	0.3	1.2
Gout (self-reported)	0.4	0.6	2.9	-1.2	-0.0	0.0	-0.3	-0.6	0.6	-1.7	-0.0	0.0	-0.9
Birth weight	0.4	1.0	2.4	-0.5	-0.8	0.0	-1.1	-1.3	-1.6	-0.1	-1.3	-0.8	-1.0
Number of full brothers	0.4	0.5	3.1	0.7	0.5	0.0	0.6	-0.2	-0.4	-1.8	0.5	0.5	0.4
Seen a psychiatrist for nerves, anxiety, tension or depression	0.4	0.5	1.3	0.4	0.8	0.7	0.9	0.7	0.8	0.0	1.1	0.7	0.6
Wheeze or whistling in the chest in last year	0.4	0.8	1.8	1.3	0.0	-1.2	0.8	0.7	-0.2	0.6	1.2	-0.3	1.3
Medication: Seretide 50 evohaler	0.4	0.4	1.6	0.1	0.3	0.7	-0.3	-0.1	0.7	1.3	-1.0	0.3	-0.9
Heart disease (mother)	0.4	0.5	1.9	-0.7	0.9	1.4	0.4	0.2	0.8	0.7	-0.4	0.6	-0.2
Ever had bowel cancer screening	0.4	0.4	2.0	-0.8	0.2	0.3	-0.5	-0.2	1.4	-0.3	-0.3	0.3	-1.1
Medication for cholesterol	0.4	0.6	1.3	0.8	-0.1	0.1	-0.7	-1.1	-0.0	-1.0	-1.1	0.0	-1.0
Asthma (self-reported)	0.4	0.7	2.8	1.7	1.0	0.1	0.7	0.6	1.2	0.4	0.3	0.8	0.3
Smoking status: Current	0.4	0.6	2.0	-0.3	-1.1	-1.4	-0.7	-0.2	-0.2	-0.9	0.6	-1.0	0.0
Average weekly beer plus cider intake	0.4	0.5	2.0	-1.1	-0.3	-1.4	-0.1	0.0	0.5	-1.1	0.4	-0.2	0.1
Risk taking	0.4	0.6	1.9	-0.4	-0.6	-0.8	-0.9	-0.7	-0.1	-1.4	-0.5	-0.7	-0.8
Pain experienced in last month	0.4	0.7	1.6	-1.3	-0.6	-1.2	0.2	0.4	-0.6	0.5	0.8	-0.5	1.2
Impedance of whole body	0.4	2.1	6.1	0.9	1.5	2.5	0.6	1.4	2.4	0.5	0.3	1.8	-0.6
Intelligence (Savage-Jansen 2018)	0.3	1.0	1.9	-0.9	-1.4	-1.4	-0.5	0.1	-1.0	1.3	0.3	-1.4	0.5
Ovarian Cancer	0.3	0.5	1.5	-0.8	0.1	0.3	-0.6	-0.2	0.9	-1.2	-0.7	0.1	-0.8
HDL Cholesterol	0.3	0.4	1.4	0.4	0.8	1.2	0.2	0.3	1.0	0.2	-0.1	0.9	-0.4
Neuroticism	0.3	0.8	3.3	0.2	1.1	1.8	0.5	0.3	1.0	0.2	0.7	1.2	-0.5
Hand grip strength (left)	0.3	0.8	2.1	0.7	-0.6	-1.2	-0.7	-1.5	0.1	-1.4	-0.7	-0.7	-0.9
Hearing difficulty/problems: Yes	0.3	0.5	1.6	1.3	0.8	1.1	0.5	-0.5	-0.1	-0.2	-0.5	0.8	-0.5
Impedance of leg (right)	0.3	1.3	3.1	0.4	0.9	1.7	-0.5	-0.1	1.8	-0.9	-1.0	1.1	-1.7
Current tobacco smoking	0.3	0.4	1.2	-0.7	-0.9	-1.1	-0.5	-0.1	-0.1	-1.0	0.5	-0.7	-0.0
Maternal smoking around birth	0.3	0.5	1.7	-0.5	-0.5	-0.6	-0.7	-0.4	0.3	-1.3	-0.1	-0.4	-1.1
Fed-up feelings	0.3	0.5	3.0	-1.7	-0.4	-0.3	-0.1	0.0	-0.8	0.5	0.3	-0.6	0.3
Heel bone mineral density (BMD) T-score, automated (left)	0.3	0.6	1.6	0.8	-0.5	-0.9	0.6	-0.4	-1.0	-1.3	0.9	-0.3	0.8
Hayfever, allergic rhinitis or eczema	0.3	0.6	1.4	0.3	0.7	-0.9	1.1	0.8	0.5	-0.0	1.2	0.8	0.8
Stomach or abdominal pain in last month	0.3	0.4	2.3	1.5	-0.1	-0.4	-0.3	-0.5	0.1	-0.8	-0.5	-0.1	-0.7
Medication: Atenolol	0.3	0.4	1.7	-0.4	0.5	1.3	0.2	0.3	0.5	0.7	-0.2	0.6	-0.4
Chronic bronchitis/emphysema (father)	0.3	0.3	1.4	-0.4	-0.3	-0.7	-0.4	-0.5	0.0	-1.2	-0.5	-0.4	-0.5
Impedance of leg (left)	0.3	1.7	4.8	0.6	1.3	2.2	-0.0	0.2	2.0	-0.7	-0.7	1.6	-1.4
Ever unenthusiastic/disinterested for a whole week	0.3	0.4	0.8	-0.7	0.7	0.5	0.8	0.6	0.7	0.1	0.9	0.6	0.5
Financial difficulties in last 2 years	0.3	0.5	2.8	0.5	-0.0	-0.3	0.2	0.3	1.0	1.7	0.4	-0.3	-0.2
Mouth/teeth dental problems	0.3	0.4	2.0	-0.5	0.2	1.4	-0.3	-0.4	0.1	0.2	-0.8	0.3	-0.8
Heart attack	0.3	0.4	1.7	0.4	-0.2	-0.6	0.2	0.6	-0.2	1.3	0.4	-0.5	0.8
Diabetes (self-reported)	0.3	0.4	1.7	-0.0	0.0	-1.3	-0.0	0.5	0.8	-1.1	0.3	0.0	0.3
Medication: Simvastatin	0.3	0.4	0.8	0.9	0.4	0.7	-0.4	-0.3	0.7	-0.9	-0.5	0.4	-0.8
Illnesses of siblings	0.3	0.4	1.0	-0.4	0.7	0.4	0.8	0.8	0.2	0.6	0.5	0.8	1.0
Alcohol intake versus 10 years previously	0.3	0.5	1.2	0.2	0.4	-0.1	0.7	1.1	0.7	1.1	0.6	0.4	0.8
Frequency of tiredness / lethargy in last 2 weeks	0.3	0.5	1.5	-1.2	0.7	0.7	0.7	0.5	0.1	-0.1	1.0	0.8	0.4
Pulse rate	0.3	0.5	1.9	-1.4	-0.3	-0.6	-0.7	-0.5	-0.1	-1.2	-0.5	-0.2	-0.5
Medication: Cholesterol lowering	0.3	0.5	1.4	-0.6	-0.4	-0.5	-1.0	-0.7	0.4	-1.0	-0.6	-0.5	-1.2
Medication: Lansoprazole	0.3	0.4	2.2	-0.6	0.6	0.4	0.5	0.3	0.5	-1.5	0.2	0.5	-0.0
Hair/balding pattern: Pattern 4	0.3	0.8	1.5	0.7	1.1	0.6	1.1	1.2	0.6	0.4	0.9	1.1	1.1
Ever highly irritable/argumentative for 2 days	0.3	0.4	1.5	-1.2	-0.8	-0.6	-0.5	-0.1	-0.3	0.3	0.1	-0.9	-0.1
Medication for cholesterol, blood pressure or diabetes	0.3	0.5	1.0	0.2	0.6	0.7	0.9	0.8	0.1	0.9	0.9	0.7	1.0
Worry too long after embarrassment	0.3	0.5	1.4	-1.1	0.7	1.2	0.7	0.3	0.1	0.4	0.6	0.9	0.1
Number of children fathered	0.3	0.4	1.4	1.2	0.6	0.8	0.5	0.2	0.2	0.5	0.4	0.7	0.1
Reason for reducing amount of alcohol drunk: Health precaution	0.3	0.3	1.0	0.1	0.7	1.0	0.5	0.4	0.8	0.3	0.2	0.8	-0.1
Medication for pain relief, constipation, heartburn	0.3	0.5	1.3	-0.4	-0.5	0.2	-0.9	-0.9	-0.2	-0.6	-1.1	-0.3	-1.2
Alcohol intake frequency.	0.3	0.7	1.7	-1.0	-0.7	-1.0	-0.6	-0.7	-1.0	-1.3	-0.7	-0.7	-0.5
Leg pain on walking	0.3	0.4	0.9	0.1	0.3	0.8	0.7	0.8	-0.4	1.0	0.5	0.4	0.6
Illness, injury, bereavement, stress in last 2 years	0.3	0.3	0.6	-0.4	0.5	0.7	0.5	0.7	-0.2	-0.5	0.5	0.8	0.8
Hypertension (Self-reported)	0.3	0.8	4.8	-2.2	0.2	0.2	0.6	1.0	0.2	1.0	0.6	0.0	0.8
Long-standing illness, disability or infirmity	0.3	0.4	1.5	0.4	-0.4	-1.2	-0.6	-0.4	-0.1	-1.2	-0.2	-0.5	-0.6
Diabetes diagnosed by doctor	0.3	0.5	2.0	0.7	-0.1	-1.4	-0.0	0.6	0.7	-1.2	0.4	-0.2	0.3
Medication: Blood pressure	0.3	0.6	2.3	-0.3	0.1	0.7	0.7	1.1	-0.1	1.5	0.8	-0.0	0.7
High cholesterol (Self-reported)	0.3	0.5	1.4	0.9	1.0	0.6	0.5	0.6	1.2	-0.4	0.4	0.9	-0.2
Heart attack/myocardial infarction (self-reported)	0.3	0.4	1.2	0.3	-0.5	-0.8	-0.1	0.4	-0.5	1.1	0.2	-0.8	0.6
Pack years of smoking	0.3	0.4	0.8	-0.9	-0.4	0.2	-0.8	-0.8	-0.4	0.0	-0.7	-0.4	-0.9
Alzheimer’s Disease (in mother)	0.2	0.2	1.0	-0.4	0.3	1.0	-0.0	0.2	0.6	0.0	-0.4	0.1	-0.2
Breast Cancer	0.2	0.5	0.8	-0.8	-0.9	0.0	-0.6	-0.2	-0.9	0.7	-0.8	-0.8	-0.4
Blood Eosinophil Count	0.2	1.7	7.1	-0.3	1.5	1.3	1.0	1.2	2.7	-0.0	1.2	1.6	-0.0
Height	0.2	3.0	6.2	0.4	-1.5	-1.3	-2.0	-2.5	-1.3	-2.2	-1.8	-1.3	-2.0
Cardiovascular Disease	0.2	0.8	3.5	-1.9	0.1	-0.7	0.7	0.9	-0.1	-0.1	1.2	-0.1	1.1
Respiratory disease	0.2	0.5	2.3	1.5	0.7	0.2	0.1	0.4	1.3	0.0	-0.2	0.6	-0.2
Supplements: Zinc	0.2	0.2	1.0	1.0	0.3	-0.3	-0.1	-0.1	0.4	0.7	-0.4	0.2	-0.3
Diabetes (father)	0.2	0.2	1.0	-0.6	0.0	0.6	-0.4	-0.2	-0.3	-0.4	-1.0	-0.1	-0.4
Age when periods started (menarche)	0.2	0.4	1.2	0.7	-1.0	-0.6	-0.4	-0.2	-0.8	0.0	0.3	-1.1	0.5
High blood pressure	0.2	0.6	3.2	-1.8	0.0	0.0	0.4	0.8	0.1	0.9	0.6	-0.2	0.7
Number of incorrect matches in round	0.2	0.3	1.0	0.1	0.0	0.6	-0.4	-0.6	-0.5	-1.0	-0.8	-0.0	-0.5
Hearing difficulty/problems with background noise	0.2	0.4	2.2	1.5	-0.2	-0.4	0.3	0.1	-0.5	0.5	0.7	-0.3	0.6
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.4	1.3	-0.2	-0.6	-0.7	0.4	-0.4	-1.1	-0.9	0.4	-0.6	0.5
Allergy	0.2	0.4	1.1	-0.4	-0.5	1.0	-0.7	-0.6	-0.6	0.1	-0.9	-0.4	-0.7
Neuroticism score	0.2	0.4	0.9	-0.8	0.7	1.0	0.6	0.2	0.4	-0.2	1.0	0.7	0.0
Impedance of arm (right)	0.2	1.1	3.3	0.9	0.8	1.7	0.2	1.2	1.8	0.0	0.4	1.2	-0.5
Worrier / anxious feelings	0.2	0.5	1.5	0.1	0.3	0.6	0.5	0.8	0.4	1.2	1.0	0.3	0.7
Falls in the last year	0.2	0.3	1.0	0.5	-0.0	0.2	-0.5	-0.7	0.1	-1.0	-0.6	0.0	-1.0
Asthma	0.2	0.3	2.1	1.5	0.6	-0.2	0.2	0.1	0.9	-0.1	-0.1	0.4	-0.1
Medication: Paracetamol	0.2	0.3	0.9	0.1	0.1	-0.9	0.4	0.1	-0.8	-0.6	0.4	0.2	1.0
Health satisfaction	0.2	0.2	0.4	-0.6	0.6	0.5	0.6	0.4	0.4	-0.1	0.4	0.6	0.3
Neck or shoulder pain in last month	0.2	0.2	0.6	0.7	0.6	0.8	0.5	0.1	-0.4	-0.2	-0.2	0.4	0.3
Medication: Aspirin	0.2	0.3	1.0	-0.2	-0.6	-0.6	-0.2	0.3	-0.4	0.6	0.4	-1.0	0.4
Handedness (chirality/laterality): Left-handed	0.2	0.2	0.6	0.2	-0.1	0.0	0.5	0.4	-0.7	0.8	0.5	-0.3	0.8
Loneliness, isolation	0.2	0.3	0.7	0.1	0.7	0.6	0.7	0.2	0.6	0.4	0.8	0.5	0.1
Ever had stillbirth, spontaneous miscarriage or termination	0.2	0.2	0.9	-0.1	0.2	-0.0	-0.3	-0.5	0.5	-0.5	-0.6	0.0	-0.9
Breast cancer (self-reported)	0.2	0.2	1.4	-0.6	-0.2	-0.6	0.1	0.1	0.1	1.2	0.4	-0.3	0.1
Medication: Aspirin	0.2	0.2	0.8	-0.5	-0.5	-0.7	-0.1	0.4	-0.3	0.4	0.3	-0.9	0.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.2	0.4	0.8	0.8	-0.7	-0.3	-0.8	-0.3	-0.3	0.3	-0.9	-0.9	-0.4
Medication: Paracetamol	0.2	0.4	0.8	0.6	0.5	-0.6	0.7	0.6	-0.1	-0.3	0.8	0.6	0.9
Irritability	0.2	0.3	1.3	-1.1	-0.3	-0.5	-0.3	-0.2	-0.5	-1.1	0.2	-0.1	-0.2
Vascular/heart problems diagnosed by doctor	0.2	0.7	2.0	1.4	-0.0	0.1	-0.5	-1.0	-0.1	-1.3	-0.8	0.3	-1.0
Cholesterol lowering medication	0.2	0.3	1.1	0.8	0.7	1.1	0.2	0.4	0.5	0.1	0.0	0.5	-0.3
Supplements: Calcium	0.2	0.3	0.8	0.2	-0.7	-0.9	-0.4	-0.3	-0.4	-0.5	-0.1	-0.8	-0.3
Neuroticism (2016)	0.1	0.2	1.2	0.0	-0.1	0.4	-0.0	-0.5	-0.4	-1.1	0.3	0.1	-0.2
Lung FEV1/FVC ratio	0.1	0.4	2.4	-0.6	-0.1	-0.3	0.1	-0.2	-1.5	-0.9	0.0	0.0	0.8
Lung FVC	0.1	0.7	1.9	0.6	0.7	0.4	0.9	1.1	0.7	0.4	1.1	0.7	1.4
Chronotype (morning person)	0.1	0.2	0.5	0.7	0.4	0.4	-0.2	-0.2	0.0	-0.3	-0.7	0.4	-0.3
Hair Pigment	0.1	3.0	7.0	0.3	1.8	1.1	1.8	2.3	1.8	2.6	1.2	1.6	1.6
Tanning	0.1	0.8	3.7	0.0	-0.3	0.9	-0.9	-0.9	0.8	-0.0	-1.1	-0.1	-1.9
Sensitivity / hurt feelings	0.1	0.2	1.1	-0.6	-0.1	-0.1	0.3	0.3	-0.3	0.4	1.1	-0.3	0.5
Frequency of unenthusiasm / disinterest in last 2 weeks	0.1	0.1	0.2	-0.2	-0.2	0.3	-0.1	-0.4	-0.4	-0.0	0.2	-0.2	-0.5
Nervous feelings	0.1	0.3	1.3	-0.5	-0.1	-0.2	0.3	0.1	-0.2	-0.8	1.2	-0.1	0.4
Hair/balding pattern: Pattern 2	0.1	0.1	0.4	-0.3	-0.2	-0.0	0.2	0.0	-0.3	0.7	0.5	-0.3	0.3
Hair/balding pattern: Pattern 3	0.1	0.2	0.5	0.2	0.4	-0.3	0.6	0.5	0.3	0.0	0.4	0.4	0.7
Noisy workplace	0.1	0.2	0.5	0.4	0.1	-0.1	-0.2	-0.5	-0.4	-0.5	-0.7	0.1	-0.5
Qualifications: A levels/AS levels or equivalent	0.1	0.3	0.6	0.7	-0.6	-0.8	-0.6	-0.3	0.5	-0.7	-0.1	-0.6	-0.5
Qualifications: College or University degree	0.1	0.3	1.7	0.5	0.5	0.4	-0.1	0.1	1.3	-0.2	-0.5	0.5	-0.4
Medication: Blood pressure	0.1	0.1	0.4	-0.5	-0.2	-0.3	-0.4	-0.3	-0.2	0.1	-0.6	-0.4	-0.3
Migraine (self-reported)	0.1	0.2	0.6	0.8	-0.3	-0.2	-0.4	-0.4	-0.5	-0.2	-0.2	-0.1	-0.5
Mood swings	0.1	0.1	0.5	0.7	0.1	0.7	-0.1	0.1	-0.1	0.3	0.1	0.0	-0.1
Mouth/teeth dental problems: Mouth ulcers	0.1	0.1	0.4	-0.4	-0.0	0.2	-0.2	-0.1	-0.2	-0.7	-0.4	0.1	-0.3
Miserableness	0.1	0.2	0.4	0.4	0.6	0.5	0.5	0.3	0.2	0.6	0.5	0.5	0.3
Guilty feelings	0.1	0.2	0.9	-0.1	0.5	1.0	-0.0	-0.0	-0.0	0.6	-0.3	0.4	-0.4
Medication: Bendroflumethiazide	0.1	0.1	0.3	0.1	-0.5	-0.5	-0.2	-0.4	-0.4	-0.0	-0.0	-0.6	-0.0
Medication: Lisinopril	0.1	0.2	0.6	-0.7	-0.5	-0.5	-0.3	0.0	-0.7	0.1	-0.1	-0.3	0.3
Fluid intelligence score	0.0	0.1	0.3	0.4	-0.2	0.2	-0.4	-0.1	0.3	-0.0	-0.1	-0.1	-0.5

Hub : Genes

MPZL3

Models

Trait associations