TWAS hub - MRPL53

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0930	0.0250	4.6e-12	0.123	0.107	0.122	0.109	0.120	9.1e-15	5.7e-13	1.3e-14	3.2e-13	2.3e-14
2	METSIM	Adipose	0.0974	0.0305	1.1e-10	0.097	0.061	0.075	0.078	0.082	2.4e-14	1.7e-09	2.7e-11	9.9e-12	2.7e-12
3	YFS	Blood	0.2010	0.0298	0.0e+00	0.327	0.310	0.327	0.327	0.328	6.8e-111	6.2e-104	9.2e-111	6.7e-111	3.8e-111
4	TCGA	Head and Neck Squamous Cell Carcinoma	0.0272	0.0176	1.7e-04	0.023	0.030	0.014	NA	0.016	1.0e-03	2.4e-04	9.7e-03	NA	6.0e-03
5	TCGA	Kidney Renal Clear Cell Carcinoma	0.0511	0.0269	6.9e-09	0.083	0.075	0.068	NA	0.077	1.2e-09	7.7e-09	4.2e-08	NA	4.8e-09
6	TCGA	Brain Lower Grade Glioma	0.0287	0.0154	8.6e-06	0.038	0.043	0.041	NA	0.038	3.2e-05	1.2e-05	1.8e-05	NA	3.4e-05
7	TCGA	Liver Hepatocellular Carcinoma	0.1530	0.0930	7.0e-03	0.001	0.038	0.044	NA	0.005	2.8e-01	6.7e-03	3.9e-03	NA	1.8e-01
8	TCGA	Ovarian Serous Cystadenocarcinoma	0.0510	0.0340	2.3e-04	0.045	0.038	0.001	NA	0.031	5.0e-04	1.3e-03	2.6e-01	NA	3.6e-03
9	TCGA	Prostate Adenocarcinoma	0.0278	0.0160	8.9e-05	0.030	0.043	0.036	NA	0.033	3.5e-04	2.3e-05	9.8e-05	NA	2.0e-04
10	TCGA	Testicular Germ Cell Tumors	0.1320	0.0880	1.9e-04	0.092	0.113	0.099	NA	0.087	3.9e-04	8.8e-05	2.3e-04	NA	5.4e-04
11	TCGA	Thyroid Carcinoma	0.0860	0.0410	4.7e-11	0.093	0.093	0.088	NA	0.089	2.4e-09	2.3e-09	6.5e-09	NA	5.1e-09

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11
Mouth/teeth dental problems: Mouth ulcers	7.5	11.9	15.0	-3.4	-3.6	-3.6	-3.4	-3.9	-3.7	-2.1	-3.4	-3.4	-3.5	-3.6
Blood Platelet Count	6.5	75.6	92.2	-9.6	-9.1	-9.3	-8.7	-8.6	-8.9	-6.1	-9.1	-8.9	-8.0	-8.8
Alzheimer’s Disease (including proxy)	6.1	8.9	10.7	3.3	3.1	3.3	2.9	2.8	3.1	1.8	3.0	3.0	3.1	3.2
Hayfever, allergic rhinitis or eczema	5.7	12.3	18.8	-3.7	-3.7	-3.6	-3.1	-3.8	-3.5	-3.0	-3.4	-3.4	-2.9	-4.3
Allergy	5.5	12.7	17.6	3.7	3.8	3.8	3.1	3.7	3.6	3.0	3.6	3.6	2.8	4.2
Falls in the last year	5.3	7.2	9.7	-2.6	-2.7	-2.8	-3.0	-2.3	-2.8	-1.9	-3.1	-3.1	-2.6	-2.4
Alzheimer’s Disease (in father)	4.9	5.3	6.1	2.3	2.4	2.4	2.4	2.2	2.4	2.0	2.4	2.5	2.4	1.9
Average weekly champagne plus white wine intake	4.3	6.0	8.0	2.4	2.8	2.5	2.7	2.3	2.5	1.7	2.5	2.7	2.3	2.3
Age at First Birth	4.2	6.0	8.4	2.0	2.7	2.4	2.9	2.4	2.5	1.6	2.6	2.6	2.5	2.4
Diabetes (father)	4.1	5.0	7.3	2.5	2.2	2.5	2.6	1.6	2.3	0.6	2.7	2.5	2.3	2.1
High blood pressure (siblings)	4.1	5.9	7.9	2.2	2.6	2.7	2.6	2.3	2.6	1.1	2.8	2.6	2.4	2.4
Alzheimer’s Disease (in mother)	4.0	4.7	7.7	2.3	2.3	2.4	2.0	2.2	2.3	0.6	2.2	2.0	2.2	2.8
Pain experienced in last month	4.0	6.7	9.5	2.4	2.8	2.8	3.0	1.9	2.5	2.4	3.0	3.1	2.3	1.9
Reproduciblity of spirometry measurement using ERS/ATS criteria	3.8	4.5	6.9	-2.5	-1.9	-2.4	-2.0	-2.1	-2.2	-0.9	-2.2	-2.0	-2.1	-2.6
Hair/balding pattern: Pattern 2	3.7	4.7	8.2	2.9	2.0	2.2	2.0	2.3	2.2	0.8	2.0	2.2	2.3	2.3
Number of operations (self-reported)	3.6	5.4	6.9	-2.0	-2.5	-2.5	-2.5	-2.5	-2.4	-2.0	-2.6	-2.5	-1.7	-2.1
Medication: Co-codamol	3.5	4.0	5.1	-1.6	-2.2	-2.2	-2.1	-1.8	-2.1	-0.8	-2.3	-2.2	-2.0	-2.3
Medication: Atenolol	3.4	4.2	5.3	2.2	2.0	2.2	1.9	2.0	2.1	1.9	2.0	2.3	2.1	1.9
Trunk fat-free mass	3.2	18.4	20.7	-4.4	-4.4	-4.4	-4.3	-4.4	-4.5	-2.8	-4.4	-4.5	-4.5	-4.3
Leg pain on walking	3.2	4.1	7.7	-1.5	-1.7	-2.1	-2.6	-1.8	-2.2	-0.4	-2.4	-2.3	-2.8	-1.1
Whole body fat-free mass	3.2	18.4	20.8	-4.3	-4.4	-4.4	-4.3	-4.4	-4.5	-2.7	-4.5	-4.6	-4.5	-4.2
Leg fat-free mass (right)	3.2	17.2	19.5	-4.1	-4.2	-4.3	-4.3	-4.2	-4.4	-2.5	-4.4	-4.4	-4.4	-4.0
Leg predicted mass (right)	3.2	17.0	19.5	-4.1	-4.2	-4.3	-4.2	-4.2	-4.4	-2.4	-4.4	-4.4	-4.4	-4.0
Allergy or Eczema	3.1	8.0	13.8	-3.0	-2.9	-2.9	-2.4	-2.9	-2.7	-2.9	-2.7	-2.6	-2.1	-3.7
Had other major operations	3.1	3.7	5.5	-1.5	-1.9	-2.0	-2.4	-1.8	-1.9	-1.8	-2.2	-2.2	-1.8	-1.6
Trunk predicted mass	3.1	17.5	19.8	-4.3	-4.3	-4.3	-4.2	-4.3	-4.4	-2.6	-4.3	-4.5	-4.4	-4.2
Medication: Seretide 50 evohaler	3.1	3.6	5.2	-1.7	-1.9	-2.1	-1.9	-1.7	-1.8	-2.3	-2.0	-2.1	-1.6	-1.7
Whole body water mass	3.1	17.6	19.8	-4.2	-4.3	-4.3	-4.2	-4.3	-4.4	-2.6	-4.3	-4.5	-4.4	-4.2
Financial difficulties in last 2 years	3.0	4.1	5.1	-2.3	-2.0	-2.1	-2.0	-2.0	-2.1	-1.7	-2.1	-2.1	-2.0	-1.8
Time employed in main current job	3.0	3.4	4.1	1.8	2.0	1.8	2.0	1.9	1.9	1.2	1.8	2.0	1.9	1.9
Wears glasses or contact lenses	3.0	3.4	4.4	-2.1	-1.8	-1.9	-1.9	-2.0	-1.9	-1.2	-1.8	-1.9	-1.8	-1.8
Arm fat-free mass (left)	2.9	14.9	16.6	-3.9	-3.9	-4.0	-3.8	-4.0	-4.1	-2.7	-4.0	-4.1	-4.0	-3.9
Leg fat-free mass (left)	2.8	14.7	17.2	-3.8	-3.9	-4.0	-4.0	-3.9	-4.1	-2.1	-4.1	-4.2	-4.1	-3.7
Medication: Levothyroxine sodium	2.8	4.8	7.1	-1.9	-2.4	-2.2	-2.5	-2.0	-2.3	-1.1	-2.4	-2.4	-2.7	-1.8
Leg predicted mass (left)	2.8	15.0	17.6	-3.8	-4.0	-4.0	-4.1	-3.9	-4.1	-2.1	-4.1	-4.2	-4.2	-3.7
Basal metabolic rate	2.8	15.6	17.9	-3.9	-4.0	-4.1	-4.0	-4.0	-4.2	-2.6	-4.1	-4.2	-4.2	-3.9
Arm predicted mass (left)	2.8	14.5	15.9	-3.8	-3.9	-3.9	-3.7	-3.9	-4.0	-2.8	-3.9	-4.0	-3.9	-3.9
Bipolar Disorder (2011)	2.7	2.6	4.1	-1.4	-1.4	-1.6	-1.7	-1.7	-1.6	-1.1	-1.5	-1.8	-2.0	-1.6
Tinnitus: Yes, but not now, but have in the past	2.7	2.9	3.4	1.8	1.8	1.7	1.8	1.6	1.7	1.8	1.7	1.9	1.6	1.2
Pulse rate	2.7	4.6	5.8	-1.9	-2.2	-2.1	-2.3	-2.4	-2.3	-1.2	-2.2	-2.3	-2.3	-2.1
Shortness of breath walking on level ground	2.7	3.3	4.8	-1.7	-1.7	-1.9	-2.1	-1.6	-1.8	-1.4	-2.2	-2.0	-1.5	-1.5
Medication: Omeprazole	2.7	3.3	5.3	1.8	1.8	1.7	1.9	2.2	2.1	0.5	1.7	1.8	2.3	1.5
Average weekly fortified wine intake	2.6	3.1	5.3	1.8	1.7	1.8	1.5	1.8	1.8	1.6	1.6	1.6	1.7	2.3
Pulse wave Arterial Stiffness index	2.6	3.0	3.5	-1.5	-1.8	-1.8	-1.8	-1.9	-1.8	-1.2	-1.8	-1.8	-1.8	-1.7
Breastfed as a baby	2.6	3.2	4.0	1.7	2.0	1.8	1.7	1.9	1.7	1.9	1.7	1.6	1.7	2.0
Comparative height size at age 10	2.6	14.4	17.6	-4.2	-4.0	-4.0	-3.6	-3.8	-3.9	-3.2	-3.8	-4.0	-3.5	-3.9
Supplements: Zinc	2.5	2.7	3.1	1.6	1.7	1.8	1.5	1.8	1.7	1.7	1.6	1.7	1.4	1.6
Pulse wave peak to peak time	2.5	2.9	3.4	1.5	1.8	1.8	1.8	1.8	1.8	1.3	1.8	1.8	1.7	1.7
Health satisfaction	2.5	3.2	4.8	-2.0	-1.9	-1.6	-2.2	-1.6	-1.9	-0.3	-2.0	-1.9	-2.0	-1.5
Illnesses of father: Heart disease	2.5	3.4	4.3	1.9	2.0	2.1	1.8	1.9	1.9	0.6	2.1	1.9	1.4	2.1
Commuting to job workplace: Walk	2.5	2.8	3.3	-1.3	-1.8	-1.8	-1.8	-1.7	-1.8	-1.0	-1.8	-1.8	-1.7	-1.6
Medication: Lansoprazole	2.4	2.7	4.1	1.8	1.7	1.4	1.6	2.0	1.8	0.6	1.3	1.4	2.0	1.9
Arm fat-free mass (right)	2.4	12.4	14.0	-3.6	-3.6	-3.5	-3.4	-3.7	-3.7	-2.8	-3.5	-3.7	-3.7	-3.5
Arm predicted mass (right)	2.4	12.4	14.1	-3.6	-3.6	-3.6	-3.5	-3.7	-3.7	-2.5	-3.5	-3.6	-3.8	-3.5
Illness, injury, bereavement, stress in last 2 years	2.4	2.9	4.9	1.6	1.7	1.8	1.5	1.9	1.6	2.2	1.6	1.6	1.7	1.4
Forced expiratory volume in 1-second (FEV1), predicted	2.4	4.9	8.5	-2.1	-2.0	-2.0	-2.2	-2.7	-2.5	-0.4	-2.2	-2.1	-2.9	-2.4
Irritability	2.4	4.1	5.6	1.9	1.9	2.1	2.2	1.8	2.2	0.2	2.2	2.3	2.4	2.1
Unable to work because of sickness or disability	2.4	3.1	4.4	-1.3	-1.8	-1.9	-2.0	-1.8	-1.9	-0.8	-2.0	-2.1	-1.9	-1.4
HbA1C	2.3	2.6	3.5	1.7	1.7	1.5	1.6	1.8	1.7	0.8	1.5	1.6	1.9	1.7
Reason for reducing amount of alcohol drunk: Health precaution	2.3	2.7	8.2	1.4	1.5	1.7	1.3	1.3	1.3	2.9	1.4	1.6	1.0	1.9
Back pain experienced in last month	2.3	3.3	8.3	-1.6	-1.9	-1.9	-1.8	-1.3	-1.5	-2.9	-1.9	-2.1	-1.1	-1.4
Medication: Omeprazole (e.g. Zanprol)	2.3	2.8	4.3	1.6	1.7	1.6	1.7	2.1	1.9	0.3	1.6	1.6	2.0	1.6
Ever had hysterectomy (womb removed)	2.2	2.4	4.5	1.6	1.7	1.3	1.7	1.6	1.7	-0.2	1.4	1.5	2.1	1.6
Mouth/teeth dental problems	2.2	3.4	5.2	1.8	2.3	1.9	2.0	1.8	1.9	1.3	2.1	1.9	1.4	1.8
Forced expiratory volume in 1-second (FEV1), predicted percentage	2.2	4.6	6.9	2.0	2.2	2.1	2.1	2.3	2.3	1.2	2.2	2.1	2.3	2.6
Age at first live birth	2.1	3.7	4.7	2.1	2.1	2.0	2.0	1.7	1.9	1.0	2.2	2.2	1.5	2.1
Schizophrenia (2014)	2.0	4.4	9.4	-2.1	-2.0	-2.2	-2.1	-1.7	-1.8	-3.1	-2.0	-2.2	-1.8	-1.8
Cholesterol lowering medication	2.0	2.9	4.2	-2.1	-1.6	-1.8	-1.8	-1.3	-1.6	-1.9	-1.8	-1.9	-1.5	-1.4
Osteoporosis (self-reported)	1.9	2.3	3.5	1.6	1.5	1.6	1.4	1.8	1.6	0.6	1.4	1.3	1.8	1.9
Ever taken oral contraceptive pill	1.9	2.1	3.1	-1.6	-1.6	-1.6	-1.6	-1.0	-1.3	-1.5	-1.8	-1.6	-1.1	-1.1
Number of live births	1.8	2.5	4.4	-2.1	-1.4	-1.6	-1.6	-1.3	-1.4	-1.8	-1.5	-1.6	-1.5	-1.5
Mouth/teeth dental problems: Bleeding gums	1.8	2.4	4.0	-1.3	-1.7	-1.2	-1.7	-2.0	-1.7	-0.5	-1.4	-1.5	-2.0	-1.5
Suffer from ‘nerves’	1.8	2.8	4.8	1.9	1.9	1.7	1.5	1.5	1.7	1.2	1.5	1.7	1.7	2.2
Knee pain experienced in last month	1.8	2.7	3.8	-1.9	-1.6	-1.8	-1.7	-1.2	-1.6	-1.9	-1.8	-1.8	-1.3	-1.3
Lupus	1.7	2.6	4.1	-1.9	-1.7	-1.6	-1.5	-2.0	-1.7	-1.2	-1.5	-1.6	-1.4	-1.5
Standing height	1.7	16.8	21.3	-4.6	-4.3	-4.2	-3.7	-4.2	-4.3	-2.6	-4.0	-4.1	-4.2	-4.6
Hair/balding pattern: Pattern 4	1.6	4.0	5.0	-2.2	-1.9	-2.0	-1.9	-2.1	-2.1	-1.9	-1.9	-2.1	-2.1	-1.7
Birth weight of first child	1.6	3.0	3.4	-1.8	-1.8	-1.8	-1.6	-1.8	-1.7	-1.8	-1.6	-1.8	-1.5	-1.8
Osteoarthritis (self-reported)	1.6	2.1	3.4	-1.6	-1.5	-1.5	-1.7	-1.3	-1.5	-1.3	-1.8	-1.6	-0.9	-1.2
Blood Eosinophil Count	1.5	11.6	14.9	-3.1	-3.2	-3.4	-3.8	-3.6	-3.6	-2.5	-3.6	-3.7	-3.9	-2.9
Height	1.5	29.6	35.5	-5.8	-5.8	-5.6	-5.1	-5.8	-5.8	-2.9	-5.5	-5.6	-5.3	-6.0
Respiratory disease	1.5	3.4	4.2	-1.7	-1.9	-2.1	-1.8	-1.8	-2.0	-1.6	-2.0	-2.0	-1.9	-1.8
Alcohol usually taken with meals	1.5	2.4	3.6	1.6	1.6	1.5	1.9	1.3	1.7	0.4	1.9	1.7	1.6	1.3
Medication: Paracetamol	1.5	2.4	3.3	-1.4	-1.5	-1.8	-1.7	-1.5	-1.7	-0.6	-1.8	-1.7	-1.8	-1.1
Age at last live birth	1.5	2.2	3.0	1.7	1.7	1.6	1.5	1.3	1.5	0.9	1.6	1.7	1.2	1.5
Financial situation satisfaction	1.5	1.9	2.8	-1.2	-1.7	-1.3	-1.4	-1.4	-1.3	-1.6	-1.4	-1.3	-1.0	-1.3
Supplements: Fish oil (including cod liver oil)	1.5	2.0	3.5	-1.9	-1.3	-1.4	-1.3	-1.6	-1.4	-0.6	-1.2	-1.2	-1.6	-1.6
Weight	1.4	6.8	8.3	-2.4	-2.6	-2.7	-2.7	-2.6	-2.7	-2.0	-2.8	-2.9	-2.8	-2.4
Tinnitus: Yes, now most or all of the time	1.4	1.6	3.2	1.8	1.0	1.4	1.2	1.3	1.3	0.7	1.2	1.3	1.4	1.1
Lung FVC	1.3	6.4	8.2	2.2	2.5	2.6	2.7	2.5	2.7	0.8	2.9	2.7	2.7	2.7
Systolic blood pressure, automated reading	1.3	3.7	4.2	2.0	2.0	1.9	1.9	1.7	1.7	2.1	1.8	2.0	1.8	1.9
Eye problems/disorders: Diabetes related eye disease	1.3	1.4	1.9	1.3	1.4	1.3	1.1	1.4	1.3	0.2	1.2	1.2	1.1	1.2
Family relationship satisfaction	1.3	1.5	2.1	1.2	1.2	1.4	1.3	0.9	1.2	0.7	1.4	1.4	1.4	1.3
Supplements: Vitamin C	1.3	1.5	2.1	1.4	1.0	1.4	1.0	1.3	1.2	1.4	1.2	1.3	1.0	1.2
Illnesses of siblings: Diabetes	1.3	1.6	3.7	-1.3	-1.1	-1.2	-1.0	-1.9	-1.4	-0.6	-1.0	-1.1	-1.7	-1.2
Mineral and other dietary supplements	1.3	1.7	2.9	1.7	1.3	1.2	1.3	1.5	1.3	-0.1	1.1	1.1	1.5	1.5
Medication: Aspirin	1.3	1.7	4.3	1.3	1.5	1.2	0.8	1.5	1.4	-0.9	1.2	0.9	1.0	2.1
Medication: Blood pressure	1.3	2.4	3.2	1.8	1.7	1.5	1.5	1.6	1.6	0.4	1.5	1.5	1.7	1.7
Systolic Blood Pressure	1.2	6.0	7.5	2.7	2.7	2.6	2.5	1.9	2.2	2.7	2.5	2.7	2.2	2.1
Average weekly spirits intake	1.2	1.4	2.0	-1.3	-1.0	-1.2	-1.4	-1.1	-1.3	-0.4	-1.4	-1.3	-1.4	-1.0
Other serious medical condition/disability diagnosed by doctor	1.2	1.6	2.6	-1.1	-1.6	-1.4	-1.3	-1.4	-1.3	-0.5	-1.4	-1.2	-1.1	-1.2
Hearing difficulty/problems with background noise	1.2	1.9	3.0	1.6	1.4	1.4	1.0	1.5	1.3	1.7	1.0	1.1	1.1	1.6
Wheeze or whistling in the chest in last year	1.2	2.1	3.0	-1.2	-1.5	-1.5	-1.7	-1.1	-1.4	-1.6	-1.7	-1.7	-1.1	-1.2
Number of children fathered	1.2	1.3	5.3	-1.2	-1.1	-0.9	-0.9	-1.0	-0.9	-2.3	-0.8	-0.9	-0.8	-0.9
Neck or shoulder pain in last month	1.2	1.7	2.5	-1.6	-1.4	-1.4	-1.4	-0.8	-1.2	-1.2	-1.5	-1.5	-0.9	-1.0
Ever had bowel cancer screening	1.2	1.4	1.8	-1.3	-1.2	-1.1	-1.3	-1.2	-1.1	-1.2	-1.2	-1.2	-1.0	-1.1
Qualifications: nursing, teaching	1.2	1.9	2.4	1.3	1.3	1.4	1.5	1.5	1.4	0.8	1.4	1.5	1.6	1.2
Number of self-reported non-cancer illnesses	1.2	2.1	4.2	-1.7	-1.3	-1.4	-1.3	-1.6	-1.3	-2.1	-1.4	-1.5	-1.1	-1.1
Medication: Lisinopril	1.2	1.5	2.8	1.4	1.3	1.1	1.3	1.0	1.3	-0.8	1.2	1.2	1.7	1.2
Crohns Disease (2012)	1.1	1.9	3.6	-1.4	-1.3	-1.5	-1.4	-1.2	-1.2	-1.9	-1.3	-1.5	-1.2	-0.9
Chronic bronchitis/emphysema (father)	1.1	1.3	2.1	-0.6	-1.4	-1.1	-1.2	-1.4	-1.2	-0.6	-1.1	-1.2	-1.3	-1.2
Pulse rate, automated reading	1.1	3.7	4.9	-1.9	-2.0	-2.1	-1.9	-1.9	-2.0	-1.1	-2.2	-2.0	-1.7	-2.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.1	1.2	2.1	1.0	1.2	1.0	1.2	1.4	1.2	0.0	0.9	1.1	1.4	1.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.1	1.3	2.7	-1.3	-1.4	-1.0	-0.6	-1.2	-1.0	-1.6	-0.7	-0.9	-0.3	-1.6
Diverticular disease/diverticulitis (self-reported)	1.0	1.2	5.8	-0.7	-1.1	-0.9	-0.4	-1.2	-0.8	-2.4	-0.5	-0.7	-0.5	-1.3
Sitting height	1.0	7.1	10.8	-2.7	-3.0	-2.6	-2.1	-3.1	-2.8	-2.0	-2.3	-2.5	-2.5	-3.3
Hypothyroidism/myxoedema (self-reported)	1.0	2.0	3.0	-1.1	-1.7	-1.4	-1.6	-1.5	-1.5	-0.5	-1.4	-1.5	-1.7	-1.3
Mouth/teeth dental problems: Loose teeth	1.0	1.2	2.4	-0.8	-1.2	-0.8	-1.1	-1.6	-1.3	0.2	-0.9	-0.9	-1.3	-1.3
Pain type(s) experienced in last month: Hip pain	1.0	1.3	2.0	-0.9	-1.4	-1.2	-1.1	-1.3	-1.2	-0.7	-1.3	-1.1	-0.8	-1.3
Ever depressed for a whole week	1.0	1.2	3.6	-1.1	-1.0	-1.0	-0.9	-1.1	-0.9	-1.9	-0.8	-0.8	-1.0	-1.0
Bipolar Disorder or Schizophrenia	0.9	2.2	12.0	-1.3	-0.9	-1.2	-1.4	-0.8	-0.9	-3.5	-1.3	-1.5	-1.1	-0.3
Major Depression (MDD)	0.9	1.1	1.7	1.3	1.3	1.1	0.9	1.0	1.0	0.9	0.9	1.0	1.2	1.0
Angina	0.9	1.1	1.8	1.4	1.2	1.2	0.9	0.9	1.2	-0.3	1.1	1.1	1.0	1.2
Impedance of leg (right)	0.9	4.4	5.7	1.9	2.1	2.2	2.3	2.1	2.3	0.8	2.4	2.2	2.2	2.0
Angina (self-reported)	0.9	1.1	1.8	1.4	1.2	1.2	0.8	1.0	1.2	-0.2	1.0	1.1	1.0	1.2
Mean time to correctly identify matches	0.9	1.8	2.6	-1.1	-1.4	-1.4	-1.5	-1.2	-1.4	-0.9	-1.4	-1.6	-1.5	-1.0
Had major operations	0.9	1.0	2.4	-0.7	-1.0	-0.9	-1.0	-1.5	-1.2	-0.2	-0.9	-0.9	-1.2	-1.0
Schizophrenia (2018)	0.8	1.6	7.3	-1.2	-0.9	-1.1	-1.1	-0.9	-0.9	-2.7	-1.0	-1.2	-1.2	-0.8
Verbal and Numeric Reasoning (VNR)	0.8	1.8	2.9	1.1	1.2	1.5	1.4	1.0	1.3	1.5	1.6	1.7	1.2	1.2
LDL Cholesterol	0.8	1.3	1.8	-0.9	-1.2	-1.1	-1.2	-1.1	-1.2	-0.4	-1.2	-1.2	-1.2	-1.3
Heel T-Score	0.8	6.1	7.9	2.4	2.6	2.6	2.8	2.6	2.7	1.2	2.7	2.7	2.5	2.0
Neuroticism	0.8	1.9	2.5	1.4	1.4	1.5	1.4	1.2	1.4	1.4	1.4	1.6	1.3	1.3
Townsend deprivation index at recruitment	0.8	1.2	1.9	-0.8	-0.9	-1.2	-1.2	-1.3	-1.2	0.0	-1.4	-1.3	-1.1	-1.1
Heel bone mineral density (BMD) T-score, automated (left)	0.8	1.8	2.4	1.1	1.5	1.3	1.5	1.4	1.4	0.8	1.4	1.4	1.4	1.2
Qualifications: A levels/AS levels or equivalent	0.8	1.8	4.0	1.3	1.3	1.3	1.4	1.0	1.1	2.0	1.4	1.5	1.0	0.9
Length of working week for main job	0.8	0.9	1.5	1.1	0.9	1.0	1.1	0.8	1.0	0.7	1.2	1.1	0.5	0.7
Chronic bronchitis/emphysema (mother)	0.8	0.9	1.2	1.1	1.0	0.9	1.0	0.9	1.0	-0.6	1.1	1.0	1.1	0.9
Number of full brothers	0.8	1.1	2.1	-1.1	-1.0	-1.4	-1.2	-0.5	-1.0	-0.5	-1.4	-1.3	-0.8	-0.5
Hearing aid user	0.8	0.9	2.1	-0.1	-1.0	-0.7	-0.9	-1.5	-1.1	0.6	-0.7	-0.5	-1.4	-1.3
Impedance of whole body	0.8	3.9	4.8	1.8	2.0	2.0	2.2	2.1	2.1	0.6	2.2	2.2	2.2	1.8
Schizophrenia vs Biploar Disorder	0.7	1.0	3.5	-1.1	-0.7	-1.1	-0.9	-0.5	-0.7	-1.9	-1.0	-0.9	-0.8	-0.7
Chronotype (morning person)	0.7	1.7	2.8	-1.2	-1.1	-1.4	-1.3	-1.3	-1.4	-0.8	-1.4	-1.2	-1.7	-1.4
Severe depression (siblings)	0.7	0.8	1.5	-1.0	-1.2	-0.8	-0.9	-1.0	-1.0	-0.1	-0.9	-0.8	-0.7	-0.9
Taking other prescription medications	0.7	1.0	5.3	-0.6	-1.0	-0.9	-0.6	-1.1	-0.7	-2.3	-0.6	-0.7	-0.4	-0.8
Impedance of leg (left)	0.7	3.6	5.0	1.6	1.9	1.9	2.2	1.9	2.0	0.1	2.2	2.1	2.1	1.7
Waist circumference	0.7	2.7	3.6	-1.3	-1.5	-1.6	-1.8	-1.7	-1.6	-1.6	-1.7	-1.8	-1.9	-1.3
Hayfever/allergic rhinitis (self-reported)	0.7	0.9	3.2	-0.5	-0.6	-0.8	-0.6	-1.3	-0.9	-1.8	-0.6	-0.8	-1.0	-0.9
Hip circumference	0.7	2.8	3.8	-1.6	-1.6	-1.8	-1.9	-1.5	-1.8	-0.9	-1.9	-1.9	-1.9	-1.5
Mouth/teeth dental problems: Dentures	0.7	1.2	3.7	0.8	0.7	0.8	0.8	1.6	1.2	-0.9	0.6	0.8	1.9	1.3
Medication: Cholesterol lowering	0.7	1.0	1.9	1.4	1.4	1.2	0.9	0.5	1.0	0.4	1.2	1.1	0.4	1.2
Impedance of arm (left)	0.7	3.3	4.2	1.7	1.8	1.8	1.9	2.1	1.9	0.9	1.9	2.0	1.9	1.9
Seen doctor (GP) for nerves, anxiety, tension or depression	0.7	1.0	1.7	-0.9	-1.0	-1.1	-1.2	-0.8	-1.0	-0.7	-1.3	-1.2	-0.9	-0.8
Asthma (self-reported)	0.7	1.3	2.7	-0.9	-1.1	-1.2	-1.0	-1.1	-1.1	-1.6	-1.2	-1.2	-1.0	-1.0
Diastolic blood pressure, automated reading	0.7	2.1	3.2	1.6	1.4	1.3	1.5	1.4	1.3	1.8	1.3	1.5	1.3	1.4
Basal cell carcinoma (self-reported)	0.7	0.8	1.3	1.0	0.9	1.1	1.1	0.6	0.9	0.2	1.1	0.9	1.0	0.4
Intelligence (Savage-Jansen 2018)	0.6	1.8	2.4	1.1	1.3	1.3	1.3	1.4	1.3	1.5	1.4	1.5	1.2	1.3
Coronary Artery Disease (CAD)	0.6	0.7	1.7	1.0	0.8	0.8	0.7	1.1	0.9	0.4	0.7	0.6	0.8	1.3
Mean Putamen Volume	0.6	0.7	1.8	-0.8	-0.7	-1.0	-0.9	-0.6	-0.7	-1.3	-0.9	-1.0	-0.8	-0.2
Fed-up feelings	0.6	1.2	2.5	1.2	0.8	0.9	1.0	1.1	1.1	-0.7	0.8	0.8	1.4	1.6
Relative age voice broke	0.6	0.9	1.3	1.0	1.0	1.1	1.0	0.6	0.9	0.7	1.1	0.9	0.8	1.1
Heel bone mineral density (BMD) T-score, automated (right)	0.6	1.4	2.0	1.0	1.3	1.1	1.3	1.4	1.2	0.7	1.2	1.2	1.2	1.1
Illnesses of siblings	0.6	0.9	2.1	-0.8	-1.1	-1.2	-1.1	-0.5	-1.0	-0.1	-1.4	-1.1	-0.6	-0.6
Asthma	0.6	1.2	2.4	-0.9	-1.1	-1.1	-1.0	-1.1	-1.1	-1.6	-1.1	-1.1	-0.9	-0.9
Medication for cholesterol, blood pressure or diabetes	0.6	1.0	2.3	-1.5	-1.3	-1.2	-0.7	-0.4	-0.9	-0.3	-1.1	-1.0	-0.2	-1.2
Eye problems/disorders: None of the above	0.6	0.7	1.8	-0.7	-1.0	-0.8	-0.6	-1.3	-0.9	-0.1	-0.7	-0.6	-0.5	-1.3
Medication: Blood pressure	0.6	1.1	2.3	1.5	1.3	1.4	0.9	0.4	1.0	0.9	1.3	1.1	0.4	0.9
Medication: Aspirin	0.6	0.9	2.6	0.9	1.0	0.8	0.5	0.9	0.9	-1.2	0.8	0.4	0.6	1.6
Mood swings	0.6	1.0	1.5	1.2	0.8	0.9	1.2	0.6	0.9	-1.2	1.0	0.9	1.0	1.0
Eye problems/disorders: Cataract	0.6	0.7	1.3	1.0	1.0	0.9	0.7	0.7	0.8	0.5	0.7	0.7	0.7	1.1
Medication: Gliclazide	0.6	0.7	3.2	-0.5	-0.7	-0.8	-0.6	-0.6	-0.6	-1.8	-0.7	-0.9	-0.4	-0.2
Mother’s age at death	0.6	0.7	1.2	-1.0	-0.7	-0.7	-1.0	-0.9	-0.8	-0.6	-0.7	-0.9	-1.1	-0.3
Pack years of smoking	0.6	0.8	4.0	0.8	0.4	0.6	0.5	0.6	0.7	-2.0	0.6	0.4	1.0	1.0
Bipolar Disorder (2018)	0.5	0.7	4.8	-0.6	-0.3	-0.5	-0.8	-0.1	-0.3	-2.2	-0.8	-0.9	-0.3	0.6
Neuroticism (Nagel 2018)	0.5	1.2	2.2	1.0	1.0	1.0	1.2	1.0	1.2	0.4	1.1	1.2	1.5	0.9
BMI	0.5	3.0	4.2	-1.3	-1.6	-2.0	-2.1	-1.5	-1.8	-1.0	-2.0	-2.0	-1.8	-1.7
Ever used hormone-replacement therapy (HRT)	0.5	0.6	3.4	-1.0	-0.7	-0.6	-0.4	-0.4	-0.3	-1.8	-0.6	-0.6	0.3	-0.7
Past tobacco smoking	0.5	1.0	2.1	0.9	1.1	1.0	0.9	1.1	1.0	0.0	1.1	0.9	0.6	1.5
Had menopause	0.5	0.7	1.1	-0.7	-0.8	-0.8	-0.8	-1.0	-0.8	-1.0	-0.7	-0.8	-0.7	-0.7
Impedance of arm (right)	0.5	2.3	3.1	1.5	1.6	1.4	1.6	1.8	1.6	0.9	1.5	1.6	1.6	1.6
Hair/balding pattern: Pattern 3	0.5	0.7	1.3	0.6	0.8	0.8	0.5	1.1	0.9	1.0	0.5	0.6	0.8	1.1
Depression (self-reported)	0.5	0.6	0.9	-0.8	-0.8	-0.8	-0.9	-0.7	-0.8	-0.0	-1.0	-0.8	-0.8	-0.5
Illnesses of mother	0.5	0.7	1.3	-0.7	-0.8	-0.9	-0.7	-0.5	-0.7	1.1	-1.0	-0.8	-0.5	-1.1
Qualifications: O levels/GCSEs or equivalent	0.5	0.8	4.8	0.7	0.8	0.8	0.5	0.6	0.5	2.2	0.5	0.6	0.5	0.6
Glaucoma (self-reported)	0.5	0.6	1.6	0.8	0.7	0.6	0.7	1.3	0.9	0.2	0.6	0.6	0.7	0.7
Worry too long after embarrassment	0.5	0.9	1.6	0.9	0.9	1.0	0.8	1.0	1.0	0.7	0.9	0.9	0.8	1.3
Medication: Ibuprofen	0.5	0.5	1.0	-0.5	-0.6	-0.8	-1.0	-0.5	-0.7	-0.7	-1.0	-0.9	-0.8	-0.2
Smoking status: Previous	0.5	0.8	1.9	-0.8	-0.9	-0.9	-0.8	-1.0	-0.9	0.3	-0.9	-0.8	-0.8	-1.4
Reaction Time	0.4	0.7	1.5	-0.5	-0.9	-0.9	-1.0	-0.6	-0.9	-0.6	-0.9	-1.1	-1.2	-0.3
Primary Biliary Cirrhosis	0.4	0.6	0.9	-0.8	-0.6	-0.8	-0.8	-0.7	-0.7	-0.7	-0.8	-0.7	-0.9	-0.6
Multivitamins +/- minerals	0.4	0.5	1.3	-1.1	-0.7	-0.6	-0.7	-0.7	-0.7	-0.1	-0.6	-0.6	-0.8	-0.8
Stomach or abdominal pain in last month	0.4	0.5	2.5	-0.5	-0.6	-0.7	-0.5	0.1	-0.3	-1.6	-0.7	-0.8	0.2	-0.3
Frequency of tenseness / restlessness in last 2 weeks	0.4	0.7	1.1	-0.6	-0.9	-0.5	-0.9	-1.0	-0.9	-0.0	-0.9	-0.8	-0.9	-1.0
Ever unenthusiastic/disinterested for a whole week	0.4	0.5	0.7	0.4	0.8	0.6	0.7	0.8	0.8	-0.2	0.8	0.8	0.6	0.7
Pain all over the body in last month	0.4	0.4	1.0	-0.4	-0.5	-0.8	-0.8	-0.4	-0.7	0.3	-1.0	-0.8	-0.5	-0.5
Medication: Simvastatin	0.4	0.6	2.0	-0.3	-0.5	-0.7	-0.8	-1.1	-0.8	-0.6	-0.6	-0.7	-1.4	-0.4
Medication: Ibuprofen (e.g. Nurofen)	0.4	0.5	0.9	-0.6	-0.6	-0.7	-0.9	-0.5	-0.6	-0.9	-0.9	-0.9	-0.7	-0.1
Medication: Amlodipine	0.4	0.5	0.8	0.6	0.9	0.8	0.6	0.8	0.7	0.8	0.7	0.6	0.4	0.8
Medication: Ventolin 100micrograms inhaler	0.4	0.5	4.2	-0.5	-0.5	-0.4	-0.2	-0.3	-0.2	-2.0	-0.2	-0.4	-0.1	-0.1
Emphysema/chronic bronchitis	0.4	0.5	4.0	-0.1	-0.4	-0.5	-0.4	-0.3	-0.2	-2.0	-0.4	-0.5	-0.2	-0.1
Medication for cholesterol	0.4	0.6	0.9	-0.8	-0.9	-0.7	-0.8	-0.9	-0.8	0.3	-0.6	-0.5	-0.9	-0.9
Miserableness	0.4	0.7	3.6	-0.6	-1.0	-0.7	-0.6	-0.6	-0.6	-1.9	-0.7	-0.8	-0.0	-0.5
Medication: Atorvastatin	0.4	0.5	1.9	0.4	0.4	0.5	0.3	0.8	0.7	-1.4	0.3	0.1	0.9	0.8
Illnesses of father: High blood pressure	0.4	0.5	1.1	0.0	0.6	0.7	0.8	0.6	0.7	0.7	0.8	1.0	0.9	0.4
Worry (Nagel 2018)	0.3	0.6	2.6	0.9	0.7	0.6	0.5	0.3	0.5	1.6	0.5	0.8	0.5	0.7
Crohns Disease (2017)	0.3	0.7	5.3	0.4	0.3	0.2	0.5	0.5	0.6	-2.3	0.4	0.0	0.9	0.6
Irritable Bowel Disease (IBD)	0.3	0.7	1.2	0.6	0.7	0.7	0.8	1.0	0.9	-1.0	0.6	0.5	1.1	0.8
Body Mass Index (BMI) (2010)	0.3	0.4	0.7	-0.5	-0.7	-0.5	-0.8	-0.7	-0.6	-0.8	-0.7	-0.5	-0.9	-0.4
Ulcerative Colitis	0.3	0.4	0.8	-0.7	-0.6	-0.5	-0.5	-0.5	-0.7	0.1	-0.5	-0.6	-0.9	-0.7
Smoking Status	0.3	0.6	1.3	-0.5	-0.9	-0.9	-1.0	-0.5	-0.8	-0.2	-1.2	-1.0	-0.6	-0.6
Medication for hormone replacement therapy	0.3	0.4	0.8	0.2	0.7	0.7	0.5	0.7	0.7	0.1	0.5	0.5	0.9	0.7
Diabetes (mother)	0.3	0.4	0.8	0.8	0.7	0.8	0.5	0.2	0.4	0.7	0.7	0.6	0.0	0.9
Pack years adult smoking proportion	0.3	0.4	3.9	0.5	0.0	0.3	0.1	0.2	0.3	-2.0	0.2	0.1	0.4	0.6
Nervous feelings	0.3	0.5	1.6	0.9	0.6	0.8	0.4	0.5	0.6	1.3	0.5	0.6	0.5	0.9
Fluid intelligence score	0.3	0.7	2.2	0.5	0.5	0.9	0.9	0.4	0.6	1.5	1.0	1.1	0.7	0.3
Neuroticism score	0.3	0.5	1.0	0.8	0.7	0.8	0.7	0.6	0.8	0.4	0.7	0.8	0.8	1.0
Father’s age at death	0.3	0.4	2.5	0.2	0.3	0.3	0.5	0.7	0.4	1.6	0.3	0.5	0.8	0.1
Happiness	0.3	0.4	0.8	-0.6	-0.9	-0.5	-0.6	-0.6	-0.6	-0.1	-0.6	-0.5	-0.6	-0.6
Peak expiratory flow (PEF)	0.3	0.6	3.1	-0.6	-0.7	-0.9	-0.3	-0.6	-0.6	-1.8	-0.5	-0.5	-0.2	-0.9
Headache pain in last month	0.3	0.5	2.0	0.7	0.4	0.5	0.3	1.4	0.6	1.1	0.1	0.5	0.6	0.8
Birth weight	0.3	0.7	1.3	-0.9	-0.8	-1.0	-0.8	-0.4	-0.7	-1.1	-1.0	-1.0	-0.4	-0.9
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.3	0.7	0.8	0.4	0.5	0.5	0.4	0.6	0.8	0.5	0.6	0.8	0.4
Heart disease (mother)	0.3	0.3	1.7	0.1	0.1	0.3	0.6	0.2	0.5	-1.3	0.7	0.4	0.6	0.1
Overall health rating	0.3	0.6	1.3	-0.6	-0.9	-0.8	-1.0	-0.5	-0.8	-0.8	-1.1	-1.1	-0.3	-0.0
Commuting to job workplace: Car/motor vehicle	0.3	0.3	1.2	0.1	0.2	0.6	0.7	0.2	0.4	-1.1	0.8	0.5	0.4	0.2
Medication: Bendroflumethiazide	0.3	0.4	1.3	0.8	0.9	0.6	0.3	0.4	0.4	1.2	0.4	0.4	-0.0	0.8
Ever had prostate specific antigen (PSA) test	0.3	0.3	1.1	-0.5	-0.4	-0.5	-0.5	-0.5	-0.5	-1.0	-0.5	-0.6	-0.3	-0.4
Commuting to job workplace: Cycle	0.3	0.4	1.3	1.1	0.7	0.5	0.5	0.6	0.5	0.7	0.5	0.7	0.4	0.4
Myopia	0.3	0.4	2.4	0.1	0.5	0.5	0.6	0.2	0.4	1.6	0.5	0.5	0.8	-0.1
Alcohol drinker status: Previous	0.3	0.3	3.0	-0.2	-0.3	-0.4	-0.3	0.1	-0.0	-1.7	-0.3	-0.4	-0.0	-0.0
Leg fat mass (left)	0.3	1.3	2.6	-0.7	-1.1	-1.1	-1.2	-1.1	-1.1	-1.6	-1.2	-1.3	-1.2	-0.9
Depressed Affect (Nagel 2018)	0.2	0.4	0.9	0.5	0.4	0.6	0.9	0.4	0.7	-0.4	0.7	0.7	1.0	0.5
Type 2 Diabetes (T2D) (2012)	0.2	0.2	0.8	-0.3	-0.8	-0.3	0.1	-0.3	-0.2	-0.4	-0.2	-0.2	-0.1	-0.9
Number of treatments/medications taken	0.2	0.3	1.3	0.9	0.5	0.2	0.3	0.1	0.4	-1.1	0.4	0.2	0.2	0.7
Hearing difficulty/problems: Yes	0.2	0.4	0.9	0.9	0.4	0.7	0.3	0.5	0.5	0.8	0.3	0.4	0.5	1.0
Medication: Metformin	0.2	0.3	0.6	-0.1	-0.7	-0.3	-0.5	-0.8	-0.5	-0.8	-0.3	-0.4	-0.5	-0.5
Current tobacco smoking	0.2	0.3	1.7	-0.2	-0.6	-0.3	-0.5	-0.2	-0.3	-1.3	-0.5	-0.6	-0.0	0.1
Maternal smoking around birth	0.2	0.2	0.7	-0.5	-0.4	-0.4	-0.6	-0.4	-0.4	-0.8	-0.6	-0.4	-0.2	-0.4
Bilateral oophorectomy (both ovaries removed)	0.2	0.3	1.0	-0.4	-0.5	-0.4	-0.3	-0.8	-0.4	-1.0	-0.4	-0.5	-0.3	-0.4
Body mass index (BMI)	0.2	1.0	1.5	-0.5	-0.8	-1.0	-1.2	-0.9	-1.0	-1.1	-1.2	-1.2	-1.1	-0.6
Trunk fat mass	0.2	0.8	2.8	-0.5	-0.8	-0.9	-0.9	-0.7	-0.7	-1.7	-0.9	-0.9	-0.8	-0.6
Qualifications: None of the above	0.2	0.3	3.6	-0.1	-0.0	-0.1	-0.0	-0.0	0.0	-1.9	0.0	-0.1	-0.1	-0.0
Heart attack	0.2	0.2	0.5	-0.3	-0.3	-0.2	-0.7	-0.5	-0.5	0.2	-0.5	-0.7	-0.7	-0.0
Frequency of tiredness / lethargy in last 2 weeks	0.2	0.3	1.0	0.7	0.4	0.5	0.2	0.7	0.6	-0.2	0.1	0.1	1.0	0.9
Noisy workplace	0.2	0.3	0.6	-0.3	-0.4	-0.4	-0.6	-0.8	-0.6	-0.6	-0.6	-0.5	-0.5	-0.4
Serious illness, injury or assault of a close relative in last 2 years	0.2	0.2	0.8	0.0	0.3	0.4	0.5	0.1	0.5	-0.9	0.6	0.6	0.1	0.4
Prospective memory result	0.2	0.2	0.7	0.9	0.4	0.4	0.5	0.3	0.4	0.4	0.4	0.5	0.5	0.1
Lung cancer (father)	0.2	0.2	0.7	-0.7	-0.4	-0.2	-0.3	-0.7	-0.4	-0.8	-0.3	-0.4	-0.0	-0.2
Arm fat mass (right)	0.2	1.0	1.7	-0.4	-0.9	-1.0	-1.1	-0.9	-1.0	-1.3	-1.1	-1.1	-1.1	-0.7
Exposure to tobacco smoke at home	0.2	0.3	2.7	-0.2	-0.0	0.0	0.0	0.2	-0.1	1.6	-0.2	0.2	-0.1	-0.2
Leg fat percentage (right)	0.2	0.6	1.1	1.1	0.9	0.8	0.5	0.9	0.9	-0.4	0.7	0.5	0.8	1.0
Exposure to tobacco smoke outside home	0.2	0.2	0.4	-0.2	-0.4	-0.3	-0.5	-0.7	-0.6	0.4	-0.5	-0.5	-0.5	-0.1
Comparative body size at age 10	0.2	0.5	1.3	-0.7	-0.7	-0.8	-0.7	-0.6	-0.7	-0.5	-0.7	-0.6	-0.6	-1.2
Medication for pain relief, constipation, heartburn	0.2	0.3	1.1	-0.6	-0.5	-0.2	-0.1	-0.6	-0.5	0.9	-0.2	-0.1	-0.3	-1.1
Whole body fat mass	0.2	0.8	2.6	-0.5	-0.8	-0.9	-0.9	-0.8	-0.8	-1.6	-0.9	-1.0	-0.9	-0.6
Leg fat mass (right)	0.2	0.7	1.5	-0.4	-0.7	-0.7	-0.9	-0.7	-0.7	-1.2	-0.8	-1.0	-0.9	-0.5
Qualifications: NVQ or HND or HNC or equivalent	0.2	0.2	0.4	-0.4	-0.6	-0.6	-0.5	-0.4	-0.5	-0.5	-0.6	-0.6	-0.3	-0.5
Hypertension (Self-reported)	0.2	0.5	0.9	0.8	0.9	0.8	0.6	0.3	0.6	0.8	0.7	0.6	0.3	0.6
Average weekly red wine intake	0.2	0.2	0.8	0.2	0.2	0.4	0.7	-0.2	0.4	-0.6	0.9	0.7	0.3	-0.1
Handedness (chirality/laterality): Left-handed	0.2	0.3	0.6	-0.4	-0.7	-0.5	-0.3	-0.5	-0.4	-0.7	-0.3	-0.5	-0.5	-0.7
Loneliness, isolation	0.2	0.3	0.5	-0.1	-0.5	-0.3	-0.7	-0.7	-0.6	0.6	-0.5	-0.3	-0.7	-0.4
Friendships satisfaction	0.2	0.2	0.5	-0.5	-0.6	-0.5	-0.7	-0.3	-0.5	0.2	-0.7	-0.5	-0.4	-0.3
Breast cancer (self-reported)	0.2	0.2	0.5	0.1	0.7	0.5	0.6	0.4	0.4	0.4	0.5	0.6	0.3	0.4
Smoking status: Current	0.2	0.3	1.4	-0.3	-0.6	-0.3	-0.5	-0.2	-0.3	-1.2	-0.6	-0.7	0.0	0.1
Commuting to job workplace: Public transport	0.2	0.2	0.6	0.6	0.6	0.2	0.2	0.5	0.4	0.7	0.2	0.3	0.1	0.4
Eye problems/disorders: Glaucoma	0.2	0.2	0.9	0.4	0.4	0.1	0.3	0.9	0.4	0.6	0.2	0.2	0.2	0.2
Alcohol drinker status: Never	0.2	0.2	0.4	0.5	0.6	0.4	0.6	0.4	0.4	0.5	0.4	0.5	0.3	0.0
Risk taking	0.2	0.3	1.7	-0.5	-0.4	-0.3	-0.0	-0.2	-0.1	-1.3	0.0	-0.3	-0.1	-0.7
Fractured/broken bones in last 5 years	0.2	0.3	1.1	0.6	0.5	0.3	0.2	0.8	0.5	-0.2	0.1	0.1	0.5	1.0
Supplements: Calcium	0.2	0.3	0.9	0.5	0.1	0.3	0.1	0.9	0.4	0.9	0.1	0.2	0.4	0.5
Heart attack/myocardial infarction (self-reported)	0.2	0.3	0.6	-0.3	-0.4	-0.3	-0.8	-0.5	-0.5	0.1	-0.6	-0.7	-0.6	-0.1
Deep venous thrombosis (DVT) (self-reported)	0.2	0.2	0.5	0.2	0.5	0.3	0.7	0.6	0.5	-0.2	0.5	0.3	0.6	0.6
Depression (Nagel 2018)	0.1	0.1	0.3	0.2	-0.2	0.1	0.1	0.3	0.2	-0.6	0.1	0.1	0.6	0.1
Ulcerative Colitis (UC)	0.1	0.3	0.5	0.4	0.5	0.6	0.5	0.7	0.5	0.7	0.4	0.5	0.4	0.4
Breast Cancer	0.1	0.3	0.9	0.4	1.0	0.5	0.5	0.6	0.5	0.6	0.4	0.6	0.0	0.6
Ovarian Cancer	0.1	0.1	0.4	-0.4	-0.1	-0.2	-0.3	-0.3	-0.2	-0.6	-0.2	-0.4	-0.5	-0.1
Fasting Glucose	0.1	0.2	0.4	-0.0	-0.2	-0.5	-0.5	-0.3	-0.4	0.6	-0.5	-0.4	-0.6	-0.2
HDL Cholesterol	0.1	0.2	0.5	-0.2	-0.3	-0.4	-0.5	-0.4	-0.4	-0.7	-0.4	-0.3	-0.4	-0.4
Neuroticism (2016)	0.1	0.2	1.5	0.2	0.4	0.3	0.1	-0.2	-0.0	1.2	0.1	0.3	0.3	0.0
Rheumatoid Arthritis	0.1	0.1	0.4	-0.2	-0.2	-0.2	-0.1	-0.1	-0.1	0.7	-0.1	0.0	0.1	-0.4
Blood White Count	0.1	0.5	0.9	-0.3	-0.6	-0.8	-0.9	-0.6	-0.7	-0.1	-0.9	-0.6	-0.8	-0.7
Waist Hip Ratio (WHR)	0.1	0.3	1.0	-0.2	-0.5	-0.1	-0.1	-1.0	-0.5	-1.0	-0.0	-0.3	-0.8	-0.4
Cardiovascular Disease	0.1	0.2	0.7	-0.1	0.0	-0.5	-0.4	-0.6	-0.4	-0.3	-0.4	-0.6	-0.8	-0.3
Hypothyroidism (self reported)	0.1	0.2	0.4	0.1	-0.6	-0.4	-0.6	-0.4	-0.4	0.4	-0.5	-0.5	-0.4	-0.3
Tanning	0.1	0.9	1.9	-1.4	-0.9	-0.9	-0.9	-0.6	-0.9	0.5	-0.9	-0.8	-1.0	-1.1
Sensitivity / hurt feelings	0.1	0.1	0.5	0.3	-0.2	0.1	0.3	0.3	0.3	-0.7	0.1	0.1	0.6	0.1
Frequency of depressed mood in last 2 weeks	0.1	0.1	0.6	0.8	0.1	0.3	0.2	0.3	0.3	0.0	0.2	0.3	0.4	0.5
Relative age of first facial hair	0.1	0.3	0.5	-0.6	-0.4	-0.4	-0.4	-0.7	-0.6	0.4	-0.5	-0.4	-0.6	-0.6
Vitamin and mineral supplements	0.1	0.1	0.2	0.4	0.3	0.2	0.4	0.4	0.3	-0.4	0.3	0.3	0.4	0.4
Frequency of unenthusiasm / disinterest in last 2 weeks	0.1	0.1	0.6	-0.1	-0.1	0.1	-0.1	0.5	0.2	-0.1	-0.3	-0.1	0.7	0.2
Age when periods started (menarche)	0.1	0.1	0.6	0.1	0.4	0.1	0.2	0.5	0.2	0.4	0.3	0.1	-0.1	0.8
Qualifications: CSEs or equivalent	0.1	0.2	1.0	0.3	0.2	0.5	0.1	0.3	0.2	1.0	0.3	0.1	0.3	0.2
Serious illness, injury or assault to yourself	0.1	0.1	0.6	0.0	-0.3	-0.0	0.2	-0.2	0.0	-0.8	0.1	-0.1	0.4	-0.1
High blood pressure	0.1	0.2	0.4	0.4	0.7	0.5	0.4	0.1	0.4	0.3	0.5	0.3	0.1	0.4
Supplements: Glucosamine	0.1	0.1	0.3	-0.6	-0.1	0.0	-0.1	0.0	-0.1	0.6	-0.0	0.0	-0.2	0.0
High blood pressure (mother)	0.1	0.1	0.3	0.4	0.3	0.4	0.5	-0.1	0.2	-0.2	0.5	0.5	0.0	0.0
Number of incorrect matches in round	0.1	0.1	0.5	0.3	0.1	0.0	0.1	0.7	0.4	-0.1	-0.0	0.0	0.7	0.2
Diabetes (self-reported)	0.1	0.1	1.0	0.0	-0.3	-0.1	-0.3	-0.4	-0.2	-1.0	-0.2	-0.2	-0.4	0.1
Arm fat percentage (right)	0.1	0.3	1.1	1.1	0.6	0.4	0.2	0.7	0.6	-0.4	0.3	0.3	0.4	0.9
Alcohol intake versus 10 years previously	0.1	0.2	0.6	-0.1	-0.2	-0.3	-0.4	-0.8	-0.6	0.4	-0.4	-0.4	-0.5	-0.3
Worrier / anxious feelings	0.1	0.2	0.5	-0.2	-0.4	-0.4	-0.5	-0.7	-0.6	0.2	-0.4	-0.3	-0.7	-0.0
Forced expiratory volume in 1-second (FEV1), Best measure	0.1	0.3	0.7	0.2	0.6	0.5	0.8	0.4	0.6	-0.3	0.8	0.7	0.6	0.6
Pulse wave reflection index	0.1	0.1	0.2	0.4	0.3	0.2	0.3	0.3	0.3	0.2	0.3	0.3	0.3	0.3
Ever highly irritable/argumentative for 2 days	0.1	0.1	0.4	0.2	-0.0	0.1	0.2	-0.1	0.1	-0.7	0.2	0.1	0.3	-0.0
Loud music exposure frequency	0.1	0.1	0.6	0.0	0.1	0.3	0.1	-0.3	0.0	-0.8	0.3	0.3	-0.3	0.2
Blood clot in the leg (DVT)	0.1	0.2	0.3	0.1	0.4	0.2	0.6	0.5	0.4	-0.2	0.4	0.2	0.5	0.5
Gout (self-reported)	0.1	0.2	0.5	-0.7	-0.1	-0.5	-0.3	0.2	-0.3	-0.0	-0.5	-0.6	-0.2	0.3
Body fat percentage	0.1	0.3	1.0	0.7	0.5	0.3	0.2	0.5	0.5	-1.0	0.3	0.2	0.4	0.6
Qualifications: College or University degree	0.1	0.4	1.8	0.6	0.3	0.4	0.3	-0.4	0.1	1.4	0.5	0.7	-0.6	-0.1
Migraine (self-reported)	0.1	0.1	0.5	0.3	-0.1	-0.2	0.0	0.2	0.1	-0.7	-0.1	-0.1	0.4	0.2
Medication: Allopurinol	0.1	0.1	0.5	-0.1	0.3	-0.1	-0.2	0.2	-0.1	0.7	-0.2	-0.2	-0.2	0.6
Alcohol intake frequency.	0.1	0.2	1.4	-0.1	-0.3	-0.6	-0.2	-0.0	-0.2	-1.2	-0.5	-0.4	-0.0	-0.5
Number of full sisters	0.1	0.2	0.5	0.1	-0.5	-0.1	-0.3	-0.7	-0.4	-0.5	-0.1	-0.3	-0.3	-0.5
Chest pain or discomfort	0.1	0.2	0.5	0.3	-0.3	0.1	-0.1	0.6	0.2	-0.7	-0.2	-0.2	0.7	0.1
Arm fat percentage (left)	0.1	0.5	1.2	1.1	0.8	0.6	0.3	0.8	0.7	-0.4	0.4	0.4	0.5	1.0
Long-standing illness, disability or infirmity	0.1	0.2	1.4	-0.1	-0.1	0.0	0.2	0.2	0.2	-1.2	-0.1	0.1	0.9	0.4
Ever had stillbirth, spontaneous miscarriage or termination	0.1	0.1	0.4	0.4	0.4	0.1	-0.2	0.6	0.1	0.4	-0.2	-0.1	0.0	0.4
Illnesses of father: None of the above (group 1)	0.1	0.1	0.5	-0.4	-0.1	-0.5	-0.5	0.1	-0.3	-0.2	-0.7	-0.6	0.0	-0.1
Arm fat mass (left)	0.1	0.6	1.3	-0.3	-0.7	-0.8	-0.9	-0.6	-0.7	-1.2	-0.9	-0.9	-0.9	-0.5
Guilty feelings	0.1	0.2	0.4	0.4	0.2	0.3	0.1	0.5	0.3	0.5	-0.0	0.2	0.7	0.5
High cholesterol (Self-reported)	0.1	0.2	1.4	-0.1	-0.2	-0.1	-0.5	-0.4	-0.2	-1.2	-0.3	-0.5	-0.4	0.1
Medication: Paracetamol	0.1	0.1	0.3	0.0	0.0	-0.4	-0.3	0.2	-0.1	0.6	-0.3	-0.3	-0.4	0.4
Leg fat percentage (left)	0.1	0.2	0.9	0.6	0.4	0.3	0.2	0.4	0.4	-0.9	0.3	0.1	0.4	0.5
Age started oral contraceptive pill	0.1	0.2	1.8	-0.3	-0.0	-0.1	0.1	0.0	0.2	-1.3	0.2	0.0	0.0	0.2
Prostate Cancer	0.0	0.1	0.4	0.3	-0.3	0.1	-0.0	-0.3	-0.1	-0.6	0.0	-0.2	0.0	-0.1
Triglycerides	0.0	0.0	0.1	-0.1	-0.2	-0.3	-0.1	-0.0	-0.2	0.1	-0.2	-0.3	-0.1	-0.0
Blood Red Count	0.0	0.4	1.1	-0.3	-0.4	-1.0	-0.6	-0.5	-0.8	0.6	-0.7	-0.5	-0.9	-0.4
Type 2 Diabetes (T2D) (2018)	0.0	0.1	0.2	-0.1	-0.1	-0.1	-0.4	-0.1	-0.2	0.5	-0.4	-0.4	-0.4	0.3
Lung FEV1/FVC ratio	0.0	0.2	0.5	0.3	-0.4	-0.7	-0.2	-0.1	-0.2	-0.5	-0.6	-0.3	0.4	-0.3
Hair Pigment	0.0	0.1	0.6	0.2	0.1	0.1	0.1	0.3	0.2	-0.8	0.0	0.2	0.3	0.5
Hand grip strength (left)	0.0	0.1	0.2	-0.0	0.2	0.2	0.5	0.1	0.2	-0.1	0.4	0.3	0.1	-0.3
Trunk fat percentage	0.0	0.2	1.3	0.5	0.3	0.1	0.1	0.4	0.3	-1.2	0.1	0.1	0.3	0.4
Hand grip strength (right)	0.0	0.0	0.1	0.0	0.1	0.0	0.3	-0.0	0.1	0.1	0.2	0.2	-0.0	-0.3
Forced vital capacity (FVC)	0.0	0.1	1.2	-0.2	-0.0	-0.0	0.2	-0.3	-0.0	-1.1	0.2	0.2	-0.1	-0.1
Medication: Ramipril	0.0	0.0	0.1	0.3	-0.2	0.1	-0.2	-0.2	-0.1	0.4	0.0	-0.2	-0.0	0.3
Forced expiratory volume in 1-second (FEV1)	0.0	0.2	0.8	0.1	0.3	0.1	0.5	0.2	0.3	-0.9	0.4	0.4	0.2	0.2
Tense / ‘highly strung’	0.0	0.1	0.2	0.2	-0.4	-0.1	-0.4	-0.3	-0.2	-0.2	-0.4	-0.1	0.1	0.1
Forced vital capacity (FVC), Best measure	0.0	0.1	0.3	-0.5	-0.0	-0.0	0.2	-0.4	-0.1	-0.6	0.2	0.2	-0.1	-0.1
Diabetes diagnosed by doctor	0.0	0.1	0.4	0.1	-0.2	0.0	-0.2	-0.4	-0.2	-0.6	-0.0	-0.2	-0.3	0.1
Ever smoked	0.0	0.0	0.2	-0.2	-0.2	-0.2	-0.2	-0.1	-0.1	0.1	-0.3	-0.2	0.2	-0.4
Average weekly beer plus cider intake	0.0	0.0	0.2	-0.2	-0.1	0.1	-0.1	-0.4	-0.1	-0.3	0.0	-0.0	-0.2	0.1
Vascular/heart problems diagnosed by doctor	0.0	0.1	0.2	-0.5	-0.5	-0.3	-0.1	0.1	-0.1	-0.3	-0.2	-0.1	0.3	-0.4
Heart disease (siblings)	0.0	0.0	0.1	0.3	0.1	0.1	0.2	0.1	0.2	0.3	0.3	0.3	0.0	-0.1

Hub : Genes

MRPL53

Models

Trait associations