Hub : Genes

MTUS1

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.2800 0.0430 0.0e+00 0.138 0.192 0.211 0.150 0.174 1.8e-16 7.3e-23 3.2e-25 7.3e-18 1.2e-20
2 GTEx Artery Aorta 0.3510 0.0700 2.6e-06 0.105 NA 0.189 NA 0.167 2.2e-06 NA 1.2e-10 NA 1.7e-09
3 GTEx Brain Caudate basal ganglia 0.4140 0.1190 5.4e-03 -0.010 NA 0.013 NA 0.042 8.6e-01 NA 1.3e-01 NA 2.4e-02
4 METSIM Adipose 0.0707 0.0230 6.2e-04 0.050 0.021 0.057 0.046 0.061 4.5e-08 3.4e-04 6.7e-09 1.8e-07 1.9e-09
5 NTR Blood 0.1593 0.0242 0.0e+00 0.113 0.099 0.154 0.136 0.149 2.5e-34 3.6e-30 2.2e-47 9.8e-42 1.0e-45
6 ROSMAP Brain Pre-frontal Cortex 0.3538 0.0474 0.0e+00 0.161 0.231 0.286 0.258 0.271 3.3e-20 2.8e-29 6.1e-37 5.0e-33 8.1e-35
7 TCGA Head and Neck Squamous Cell Carcinoma 0.0434 0.0207 6.3e-03 0.002 0.019 0.005 NA 0.003 2.0e-01 3.1e-03 7.9e-02 NA 1.2e-01
8 TCGA Kidney Renal Clear Cell Carcinoma 0.1758 0.0442 7.4e-09 0.105 0.077 0.110 NA 0.119 7.3e-12 4.9e-09 2.1e-12 NA 2.5e-13
9 TCGA Brain Lower Grade Glioma 0.0836 0.0272 1.8e-07 0.069 0.066 0.064 NA 0.086 3.1e-08 5.9e-08 8.0e-08 NA 5.4e-10

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bipolar Disorder (2018) 1.5 2.4 6.1 2.5 -0.4 1.5 0.6 -0.1 2.2 1.1 -0.9 2.3
Bipolar Disorder or Schizophrenia 1.3 3.1 10.4 3.2 -0.6 1.0 1.0 -0.8 2.4 0.6 -1.0 2.7
Depressed Affect (Nagel 2018) 0.3 0.7 3.0 0.0 -0.7 1.7 0.1 0.1 0.1 1.7 -0.1 0.3
Depression (Nagel 2018) 0.3 0.5 1.5 0.1 -0.4 0.9 0.2 1.0 0.5 1.2 0.8 0.2
Intelligence (Savage-Jansen 2018) 0.6 1.8 5.4 0.6 0.8 2.3 2.3 1.4 0.9 0.0 0.8 0.9
Neuroticism (Nagel 2018) 0.6 1.5 7.8 0.3 0.0 1.2 0.6 -0.0 1.1 2.8 1.2 1.0
Schizophrenia (2018) 0.6 1.2 4.8 2.2 -0.5 0.1 0.8 -1.0 1.2 -0.0 -0.6 1.6
Schizophrenia vs Biploar Disorder 0.5 0.6 2.2 -0.4 0.3 -1.5 -0.6 -0.9 -0.1 -1.0 -1.0 0.4
Worry (Nagel 2018) 0.7 1.5 4.6 0.9 -0.8 0.4 0.5 -0.3 2.2 2.1 0.6 1.6
Alzheimer’s Disease (in mother) 0.4 0.5 2.0 -0.8 -0.4 0.0 -1.2 -1.4 -0.6 -0.1 0.3 0.1
Alzheimer’s Disease (in father) 0.3 0.3 0.8 -0.3 0.8 0.7 -0.0 -0.3 -0.5 -0.4 0.4 -0.9
Alzheimer’s Disease (including proxy) 0.7 1.0 2.5 -1.1 -0.0 -0.1 -1.3 -1.6 -1.2 -1.1 0.8 -0.6
Crohns Disease (2017) 0.6 1.3 3.6 1.3 0.9 0.2 0.6 -1.4 1.6 0.8 0.1 1.9
Irritable Bowel Disease (IBD) 0.7 1.6 6.5 1.3 2.5 1.4 0.7 -0.2 0.7 0.6 1.1 1.3
Ulcerative Colitis (UC) 0.8 1.5 6.9 0.7 2.6 1.4 0.3 0.7 -0.4 0.6 1.8 0.4
Major Depression (MDD) 1.6 2.0 4.9 1.3 -1.5 -0.0 -0.8 1.1 1.1 2.2 -1.1 2.2
Reaction Time 1.3 2.5 7.4 2.4 0.2 -1.0 1.1 1.3 2.7 0.5 -0.8 2.1
Verbal and Numeric Reasoning (VNR) 0.5 1.1 6.4 0.8 -0.9 2.5 0.8 0.6 0.8 -0.2 0.4 0.7
Breast Cancer 0.6 1.5 2.3 -1.2 1.5 -1.2 0.9 -1.4 -1.1 -0.8 1.4 -1.3
Ovarian Cancer 1.0 1.3 3.9 -0.5 1.8 0.1 1.0 0.8 -0.2 1.6 2.0 -0.4
Prostate Cancer 0.3 0.4 1.4 -0.9 0.5 1.2 0.2 -0.8 -0.0 0.4 0.1 0.1
Age at First Birth 0.5 0.8 2.2 -0.0 1.3 1.3 1.5 0.6 0.4 0.3 1.0 0.1
Bipolar Disorder (2011) 2.1 2.0 3.6 1.7 -1.9 1.2 -1.2 -1.6 1.2 -0.5 -1.4 1.6
Body Mass Index (BMI) (2010) 1.7 2.3 5.7 -1.0 1.2 -0.9 2.3 2.4 -1.0 -0.4 1.9 -1.3
Coronary Artery Disease (CAD) 1.4 1.6 5.6 1.2 -1.4 0.1 -1.0 -0.6 0.0 -2.0 -2.4 0.6
Crohns Disease (2012) 0.8 1.3 2.6 1.0 -1.4 0.5 -0.3 -1.2 1.6 -0.2 -1.6 1.3
Mean Putamen Volume 1.1 1.3 3.5 -1.9 0.9 1.5 0.7 -0.4 -1.3 -0.9 0.5 -1.1
Fasting Glucose 2.1 2.5 4.3 -0.8 -2.0 -0.1 -2.1 -1.6 -2.0 -1.9 -0.6 -1.8
HbA1C 0.4 0.4 2.2 -0.2 -0.1 0.4 -0.2 -0.4 0.8 1.5 0.7 -0.0
HDL Cholesterol 0.2 0.3 1.3 -0.9 0.7 0.0 -0.1 -0.1 0.5 1.1 0.1 -0.4
LDL Cholesterol 0.8 1.2 4.4 -0.4 1.7 0.7 0.0 1.4 -0.7 0.5 2.1 0.2
Lupus 0.6 0.9 3.7 -0.2 -1.0 -0.4 -1.6 -1.9 0.0 -0.4 -0.1 0.3
Neuroticism (2016) 0.5 0.7 2.6 0.3 -1.6 1.5 0.1 -0.8 0.8 0.3 -0.5 -0.3
Primary Biliary Cirrhosis 0.5 0.6 2.0 0.3 -0.4 -1.0 -1.1 -0.7 -0.8 -1.4 -0.2 0.1
Rheumatoid Arthritis 1.8 2.5 8.2 2.9 0.0 0.3 2.0 -0.4 2.6 -1.1 -0.8 1.3
Schizophrenia (2014) 1.0 2.1 7.5 2.7 -0.8 0.7 1.0 -0.4 2.0 -0.2 -1.3 1.9
Triglycerides 0.5 0.8 2.9 -0.0 0.1 -1.2 0.1 1.3 -1.7 -0.6 0.8 0.2
Type 2 Diabetes (T2D) (2012) 0.5 0.6 2.0 0.4 -0.1 0.1 0.5 -0.5 1.4 0.9 -0.8 0.9
Ulcerative Colitis 0.4 0.5 1.4 0.8 0.8 0.8 1.2 0.7 -0.0 -0.2 0.8 0.1
Blood Eosinophil Count 0.1 0.7 3.7 -0.2 0.1 -0.7 0.8 1.9 0.1 0.2 -1.1 0.4
Blood Platelet Count 0.1 0.7 3.1 -0.1 0.4 0.4 1.3 1.8 -0.5 -0.3 0.7 0.2
Blood Red Count 0.1 0.6 2.2 1.0 -0.5 -1.5 0.9 -0.2 0.3 0.3 -0.8 -0.3
Blood White Count 0.1 0.7 2.7 0.2 -0.4 -1.6 0.2 -0.1 0.2 -0.4 -1.5 0.7
Heel T-Score 0.5 4.0 11.0 3.3 0.3 -1.4 -0.6 -0.6 3.1 1.6 0.1 3.1
BMI 0.4 2.4 5.8 -2.1 0.0 -1.2 -0.3 -1.3 -2.4 -1.6 0.4 -2.3
Height 0.6 11.1 26.4 -3.8 1.3 4.7 0.6 5.1 -3.7 1.9 2.7 -3.1
Waist Hip Ratio (WHR) 0.6 2.6 12.0 -1.1 0.7 -1.3 0.9 1.7 -0.8 -3.5 -0.7 -1.7
Systolic Blood Pressure 0.4 1.9 7.1 -1.3 1.0 -2.1 0.2 -1.1 -0.9 0.2 2.7 -1.1
Smoking Status 0.8 1.9 5.6 -1.4 -0.3 -1.9 -1.0 -1.2 -1.1 -2.4 -1.5 -0.5
Allergy or Eczema 0.1 0.4 1.6 0.5 0.2 -0.1 -0.5 -1.1 1.3 0.4 0.2 0.2
Cardiovascular Disease 0.2 0.5 1.9 -0.2 0.3 -0.6 -0.6 -1.4 -0.1 0.6 1.2 -0.1
Hypothyroidism (self reported) 0.2 0.4 1.7 -0.3 0.5 0.8 1.3 -0.7 0.7 0.5 -0.1 0.4
Respiratory disease 1.1 2.4 5.7 -2.0 -0.7 -0.9 -1.0 -0.5 -2.2 -2.1 -0.3 -2.4
Type 2 Diabetes (T2D) (2018) 1.8 3.4 8.1 -0.9 -1.8 -1.8 -1.4 -1.8 -2.2 -2.9 -2.0 -1.1
Lung FEV1/FVC ratio 2.3 11.9 34.5 5.4 2.9 -1.7 0.7 -1.6 5.1 1.4 -1.3 5.9
Lung FVC 0.2 0.9 2.1 -0.4 0.6 -1.2 0.2 1.4 -0.3 1.5 1.3 0.1
Neuroticism 0.3 0.8 4.4 0.2 -0.0 0.9 0.7 -0.1 0.8 2.1 0.5 1.0
Chronotype (morning person) 0.9 2.1 7.6 0.9 0.2 1.1 2.7 1.7 1.3 2.1 0.1 0.3
Hair Pigment 0.0 0.5 1.5 -0.7 -0.0 0.9 -0.2 1.2 -0.6 -0.0 0.8 -0.7
Tanning 0.0 0.5 2.2 0.0 -0.3 0.6 0.0 1.5 0.4 0.8 -0.8 0.6
Hand grip strength (left) 0.6 1.5 8.1 -0.3 -0.9 -0.4 -0.4 -1.1 -1.2 -2.8 -1.2 -0.4
Number of treatments/medications taken 0.4 0.6 3.7 -0.0 0.1 -0.7 0.3 -1.9 -0.0 0.7 0.9 -0.4
Average weekly spirits intake 0.4 0.5 3.0 -0.1 -0.2 0.1 0.1 1.7 -0.7 0.1 0.2 -0.9
Sensitivity / hurt feelings 0.6 1.0 2.4 -0.5 1.1 -0.4 1.6 0.4 -0.1 1.5 1.5 -0.4
Frequency of depressed mood in last 2 weeks 0.4 0.5 2.1 0.1 -1.4 -0.1 0.2 0.6 0.2 1.4 0.0 -0.2
Hearing difficulty/problems: Yes 0.1 0.2 1.0 -0.1 0.3 -0.4 0.4 0.0 -0.5 1.0 0.2 -0.1
Relative age of first facial hair 0.4 0.8 2.6 0.1 -1.2 0.2 0.7 -1.2 -0.1 -1.6 -1.2 -0.1
Other serious medical condition/disability diagnosed by doctor 1.5 2.0 5.1 -0.1 2.2 -0.1 2.3 0.8 0.8 1.2 2.3 0.1
Ever used hormone-replacement therapy (HRT) 1.7 2.1 4.4 1.4 -2.0 -0.2 -2.1 -1.8 1.2 0.2 -1.8 0.9
Ever had hysterectomy (womb removed) 1.6 1.9 7.5 2.7 0.0 1.0 -0.3 -0.6 2.1 0.1 0.3 1.8
Systolic blood pressure, automated reading 0.6 1.8 7.6 -1.4 0.5 -2.8 0.0 -1.3 -0.7 -0.2 1.3 -1.5
Eye problems/disorders: Diabetes related eye disease 0.4 0.5 2.0 0.9 0.1 0.3 -0.1 -1.4 1.0 0.2 -0.1 0.7
Angina 0.7 0.9 3.5 -0.6 0.9 0.6 1.9 0.6 -0.6 -0.0 1.3 -1.1
Medication for hormone replacement therapy 3.5 3.9 9.5 2.4 -0.4 -1.0 -1.5 -2.2 2.6 2.0 -0.7 3.1
Vitamin and mineral supplements 0.8 1.2 4.7 -0.4 1.2 -2.2 1.7 0.8 0.1 -0.1 0.3 0.5
Supplements: Zinc 2.1 2.3 4.2 0.5 2.0 1.9 1.1 1.6 0.8 2.0 1.9 0.6
Medication: Co-codamol 0.7 0.8 1.6 -1.1 -1.2 -1.3 0.4 0.2 -1.2 -0.3 0.5 -0.8
Medication: Metformin 1.0 1.4 1.8 -0.6 -1.0 -1.3 -1.2 -1.3 -1.1 -1.4 -1.2 -1.1
Diabetes (father) 1.0 1.3 4.8 0.3 -1.4 0.5 -0.3 -0.3 -1.1 -2.2 -1.7 -0.6
Diabetes (mother) 0.3 0.4 1.5 -0.1 -0.0 -0.9 -0.8 -1.2 -0.1 -0.9 -0.1 0.3
Severe depression (siblings) 0.4 0.5 3.8 0.4 -0.2 1.9 0.2 -0.5 0.0 0.3 -0.1 0.4
Pack years adult smoking proportion 0.4 0.7 1.8 -0.6 0.0 -0.2 -1.3 -1.2 -0.7 -1.0 -0.5 -0.7
Impedance of leg (right) 0.4 1.8 5.9 1.2 -0.8 -1.8 -0.2 1.2 2.4 0.6 -1.2 1.4
Leg fat-free mass (left) 0.6 3.1 6.8 -2.0 2.2 1.9 0.7 0.7 -2.6 0.2 2.4 -1.4
Trunk fat percentage 0.6 2.4 7.7 -2.8 0.6 -1.2 -0.1 0.0 -1.6 -1.0 1.0 -2.7
Hand grip strength (right) 0.3 0.8 4.5 -0.6 -0.1 0.5 0.2 -0.2 -1.4 -2.1 -0.3 -0.4
Townsend deprivation index at recruitment 1.4 1.9 5.8 -2.4 -0.4 -0.8 -1.3 -0.3 -1.9 -1.3 -0.3 -1.9
Current tobacco smoking 1.6 2.7 9.1 -1.0 -1.1 -3.0 -1.6 -1.6 -0.8 -1.9 -1.8 -0.1
Average weekly fortified wine intake 0.2 0.3 1.2 -0.2 0.4 0.1 0.6 0.6 -0.2 -0.5 0.5 -1.1
Maternal smoking around birth 0.5 0.7 1.8 1.2 -0.1 -1.0 -0.3 -0.4 1.3 0.7 0.1 1.2
Fed-up feelings 0.2 0.3 0.7 -0.8 -0.8 -0.1 -0.1 0.0 -0.8 0.8 -0.2 -0.4
Frequency of unenthusiasm / disinterest in last 2 weeks 0.2 0.3 1.4 -0.4 -0.9 -0.2 -0.0 -0.1 0.2 1.2 0.4 -0.1
Relative age voice broke 0.8 1.2 4.5 -0.8 0.4 -1.3 1.1 -1.1 -0.2 -2.1 0.2 -1.1
Taking other prescription medications 0.2 0.3 1.2 0.0 0.1 -0.2 0.1 -1.0 -0.2 -1.1 0.6 -0.7
Age when periods started (menarche) 0.2 0.5 1.8 -0.4 0.0 0.1 1.0 -1.4 -0.2 -0.7 0.6 -0.6
Bilateral oophorectomy (both ovaries removed) 0.7 0.8 3.3 0.5 0.6 0.6 -0.0 -1.8 1.4 -0.4 0.7 0.4
Heel bone mineral density (BMD) T-score, automated (left) 0.5 1.1 2.3 1.3 0.3 -1.5 -0.6 1.4 0.8 1.2 -0.2 1.2
Tinnitus: Yes, but not now, but have in the past 2.0 2.1 4.7 1.7 -1.8 -0.6 -2.2 -0.1 0.8 1.0 -1.8 1.7
Qualifications: CSEs or equivalent 0.5 0.7 1.7 -0.7 0.2 -0.8 -1.3 -1.3 -0.5 -0.5 0.1 1.1
Serious illness, injury or assault to yourself 1.8 2.2 6.1 -1.8 1.6 -0.7 1.9 1.2 -1.2 -0.1 2.5 -0.8
High blood pressure 0.3 0.9 4.2 0.1 -0.0 -1.3 -0.8 -2.0 -0.1 0.7 1.0 -0.5
Hayfever, allergic rhinitis or eczema 0.2 0.4 0.9 0.2 -0.2 0.8 -0.8 -0.8 0.9 0.7 0.2 0.0
Multivitamins +/- minerals 0.3 0.4 1.5 0.6 -0.9 1.2 -0.5 0.3 0.5 -0.2 -0.2 0.0
Stomach or abdominal pain in last month 0.4 0.5 3.2 0.3 -0.3 -0.3 -1.8 0.2 -0.7 -0.3 -0.7 0.0
Supplements: Glucosamine 0.9 1.2 5.2 -1.3 -0.6 2.3 0.7 0.1 -1.0 -0.2 -0.5 -1.3
Diverticular disease/diverticulitis (self-reported) 1.8 2.2 6.5 -0.1 2.5 -0.9 2.0 1.5 -1.0 0.0 2.3 0.0
Medication: Atenolol 0.9 1.1 2.3 -1.4 -0.7 -0.9 1.1 -1.3 -0.6 0.5 0.8 -1.5
Medication: Levothyroxine sodium 0.2 0.3 0.9 -0.0 -0.1 0.9 0.3 -0.5 1.0 0.8 -0.1 0.2
Sitting height 0.3 2.3 5.4 -0.4 1.9 2.0 0.2 2.2 -0.6 1.4 2.3 0.4
Chronic bronchitis/emphysema (father) 0.6 0.8 2.5 -1.6 -0.4 -0.3 0.4 0.0 -0.9 -0.6 -0.0 -1.6
High blood pressure (mother) 1.5 2.2 8.9 -0.4 1.6 -3.0 0.9 0.5 -0.8 -1.0 2.0 -1.1
Body mass index (BMI) 0.5 2.0 4.8 -2.2 0.3 -0.3 -0.4 -1.8 -2.1 -0.9 0.8 -2.0
Impedance of leg (left) 0.4 1.9 5.0 0.9 -1.7 -1.9 -0.9 0.9 2.2 -0.2 -1.6 1.1
Leg predicted mass (left) 0.6 3.1 6.4 -2.0 2.3 2.0 0.7 0.7 -2.5 0.3 2.4 -1.3
Trunk fat mass 0.6 2.5 8.3 -2.9 0.9 -0.4 0.0 0.1 -2.0 -0.6 1.5 -2.5
Waist circumference 1.0 3.6 9.6 -2.9 0.4 -0.4 0.0 -0.1 -2.8 -2.4 0.6 -3.1
Number of incorrect matches in round 0.2 0.4 0.9 0.9 0.3 -0.4 0.3 0.6 0.4 -0.8 -0.8 0.4
Past tobacco smoking 0.7 1.3 3.1 1.3 -0.1 0.7 0.4 -0.6 1.6 1.8 0.4 1.7
Alcohol usually taken with meals 0.8 1.3 4.7 1.3 0.1 -0.7 -0.4 -1.0 1.2 2.2 1.0 1.1
Nervous feelings 0.6 1.1 3.3 1.1 -1.8 0.2 0.9 0.4 1.8 0.5 -0.3 1.0
Frequency of tenseness / restlessness in last 2 weeks 0.6 1.0 3.7 -0.3 -0.5 -1.3 1.0 1.9 -0.2 1.4 0.4 -0.2
Hearing difficulty/problems with background noise 0.4 0.7 2.4 -0.4 0.8 1.0 -0.2 -0.4 -0.7 1.5 1.1 -0.4
Hair/balding pattern: Pattern 2 1.7 2.1 4.8 -1.6 -1.9 1.7 -0.2 0.7 -1.9 -0.7 -0.5 -2.2
Had menopause 0.8 1.0 3.7 -0.8 -0.7 -1.5 -0.2 -0.5 -1.1 -0.1 0.2 -1.9
Had other major operations 0.7 0.9 2.3 -0.0 0.8 0.3 0.8 1.2 -0.6 -1.3 0.9 -1.5
Forced vital capacity (FVC) 0.5 1.9 6.9 -0.1 1.5 1.7 -0.0 2.6 -0.4 0.8 2.0 -0.0
Heel bone mineral density (BMD) T-score, automated (right) 0.6 1.5 3.6 1.1 0.6 -1.7 -0.6 0.9 1.1 1.6 0.1 1.9
Ever unenthusiastic/disinterested for a whole week 1.0 1.2 4.4 1.0 -2.1 -1.6 0.7 0.2 0.7 -0.4 -1.1 0.6
Qualifications: None of the above 0.9 2.0 12.6 -0.1 -0.2 -3.6 0.7 -0.7 -0.0 -1.2 -1.5 -0.7
Financial difficulties in last 2 years 0.6 0.8 1.4 -0.8 -0.5 -1.0 -1.2 -0.3 -1.2 0.6 1.2 -0.5
Mouth/teeth dental problems 0.5 0.7 2.9 0.1 0.9 1.7 0.6 0.1 1.1 0.5 0.8 0.6
Heart attack 0.7 0.8 2.6 -1.0 0.3 -0.5 -0.2 -0.8 -1.1 -1.2 -0.5 -1.6
Allergy 0.3 0.7 4.1 0.7 0.5 -0.2 2.0 0.6 0.1 -0.5 -0.8 0.5
Pain all over the body in last month 0.8 0.9 3.6 0.4 0.5 0.9 -1.0 0.0 0.7 1.9 0.8 1.0
Diabetes (self-reported) 1.6 2.5 7.5 -0.8 -0.7 -0.0 -0.9 -1.7 -2.2 -2.7 -1.2 -1.8
Hayfever/allergic rhinitis (self-reported) 0.9 1.2 3.1 -0.5 1.3 -1.4 1.2 -0.9 -0.0 -0.0 1.8 -0.9
Medication: Ramipril 0.2 0.3 0.8 0.3 -0.9 0.3 0.1 0.5 0.5 0.4 -0.7 0.7
Medication: Simvastatin 0.8 1.1 4.0 -1.3 -0.6 -0.8 0.2 -0.7 -1.1 -1.0 0.5 -2.0
Fluid intelligence score 0.3 0.5 2.1 0.6 -1.4 0.9 0.1 0.4 0.6 -0.8 0.1 0.4
Illnesses of siblings 3.6 5.0 15.7 2.6 0.4 1.8 -0.2 1.2 2.7 3.2 0.1 4.0
Neuroticism score 0.2 0.3 1.3 -0.1 -0.7 0.2 1.1 0.4 0.3 1.0 -0.0 -0.1
Weight 0.5 2.3 5.4 -2.3 1.2 0.9 -0.1 0.0 -2.3 -0.0 2.0 -1.9
Impedance of arm (right) 0.2 1.1 5.5 0.3 0.8 -0.9 0.6 2.4 1.5 0.2 -0.5 0.5
Arm fat percentage (right) 0.4 1.6 4.9 -2.2 0.7 -0.9 -0.1 -0.7 -1.5 -0.6 0.9 -2.1
Trunk fat-free mass 0.5 2.7 8.3 -0.7 2.1 2.9 0.2 0.6 -1.5 1.1 2.6 -0.2
Hip circumference 0.7 2.9 8.4 -2.9 0.7 0.4 -0.1 -0.7 -2.5 -0.7 1.8 -2.6
Time employed in main current job 0.3 0.3 1.0 0.0 -1.0 0.1 0.2 -0.6 0.0 -1.0 -0.7 -0.2
Alcohol intake versus 10 years previously 0.6 0.9 2.7 -1.0 -0.9 -1.7 -0.2 0.7 -1.1 -1.0 -0.7 -0.6
Father’s age at death 0.6 0.8 2.3 0.4 -1.5 1.1 0.9 1.0 0.4 0.7 -1.1 0.1
Worrier / anxious feelings 0.9 1.7 5.5 1.6 -0.2 0.3 1.1 0.5 2.4 2.1 0.1 0.9
Frequency of tiredness / lethargy in last 2 weeks 0.5 0.8 2.3 -1.1 -0.4 1.0 -0.5 0.9 -0.8 1.5 0.4 -0.9
Falls in the last year 0.2 0.3 1.0 -1.0 0.3 0.7 0.3 -0.3 -0.5 -0.3 -0.2 -0.3
Hair/balding pattern: Pattern 3 1.3 1.9 7.6 -0.7 2.8 -1.6 1.6 0.4 -0.9 -0.6 1.7 -0.7
Number of live births 1.4 2.0 7.9 -0.1 0.2 2.3 0.8 0.8 1.0 2.8 -0.5 1.4
Forced expiratory volume in 1-second (FEV1) 0.8 2.8 6.2 1.6 2.5 1.1 0.5 2.3 1.2 1.5 1.7 1.8
Pulse rate 0.3 0.6 3.0 0.5 -0.3 0.8 1.7 -0.6 -0.0 -0.9 0.2 -0.2
Happiness 0.8 0.9 4.5 2.1 -0.8 0.5 1.1 0.2 0.8 0.1 -0.5 0.9
Noisy workplace 1.9 2.4 5.8 -2.4 -0.6 -1.3 -0.6 1.9 -2.3 -0.3 0.0 -2.2
Qualifications: A levels/AS levels or equivalent 1.1 2.3 12.0 0.6 -0.4 3.5 0.8 2.7 -0.4 -0.5 -0.1 -0.3
Serious illness, injury or assault of a close relative in last 2 years 0.6 0.7 4.0 -0.0 -0.3 0.8 0.1 2.0 0.3 0.9 0.0 0.4
Mouth/teeth dental problems: Dentures 0.6 1.0 3.0 0.1 -0.3 -1.7 -0.3 -0.8 -0.3 -1.7 -1.3 -1.0
Asthma 0.5 1.1 3.0 -1.3 -0.7 0.4 -1.7 -0.5 -1.3 -1.2 -0.1 -1.0
Medication: Ibuprofen (e.g. Nurofen) 0.3 0.3 0.7 0.4 0.7 -0.8 0.7 0.5 0.4 0.3 -0.7 0.6
Medication: Cholesterol lowering 0.7 1.1 3.8 -0.5 -1.9 -0.5 -0.4 -1.7 -0.2 -0.6 -1.3 -0.5
Depression (self-reported) 1.0 1.2 3.5 -0.8 -1.6 1.9 -0.2 0.2 -1.0 -1.2 0.3 -1.2
Medication: Lansoprazole 2.6 3.0 16.2 0.6 1.4 1.2 0.2 0.1 1.3 4.0 1.6 1.6
Prospective memory result 0.7 0.9 2.3 1.5 -0.0 0.9 0.9 1.2 1.5 0.1 0.0 0.8
Lung cancer (father) 0.9 1.0 2.7 -1.2 0.9 -0.1 0.6 1.4 -0.7 -1.4 0.2 -1.6
Illnesses of mother 1.8 2.2 9.5 1.3 -0.5 3.1 -0.1 0.6 1.6 0.3 -1.5 1.7
Forced expiratory volume in 1-second (FEV1), Best measure 1.1 3.7 7.3 2.0 1.6 1.9 0.9 2.7 1.7 2.0 1.3 2.4
Pulse wave Arterial Stiffness index 1.3 1.5 5.2 -1.8 -0.2 -1.5 -0.8 -2.3 -0.4 -0.4 0.1 -1.3
Impedance of arm (left) 0.3 1.2 7.9 -0.1 0.4 -0.8 0.6 2.8 1.0 0.4 -0.7 0.0
Arm fat mass (right) 0.5 2.0 5.5 -2.3 1.1 -0.3 -0.0 -0.5 -1.8 -0.4 1.6 -2.1
Trunk predicted mass 0.4 2.6 8.1 -0.7 2.1 2.8 0.2 0.5 -1.5 1.0 2.5 -0.3
Standing height 0.5 5.0 14.8 -0.5 2.3 3.3 0.7 3.9 -0.6 1.9 3.0 0.1
Length of working week for main job 0.9 1.0 2.8 0.7 0.5 1.2 -0.4 -1.7 0.5 0.8 0.9 1.5
Exposure to tobacco smoke at home 0.3 0.3 1.2 -0.1 -0.4 0.4 -0.2 -1.1 -0.2 -1.0 -0.4 -0.7
Breastfed as a baby 0.3 0.4 1.3 0.0 -0.3 -0.1 -1.1 0.8 -1.1 0.4 -0.2 -0.7
Tense / ‘highly strung’ 0.3 0.4 1.0 0.2 -1.0 -0.9 0.9 -0.3 1.0 -0.1 -0.4 0.2
Seen doctor (GP) for nerves, anxiety, tension or depression 0.7 1.1 6.1 1.1 -2.5 -0.2 0.1 -0.3 0.8 -0.9 -0.7 0.1
Hair/balding pattern: Pattern 4 1.0 2.5 8.5 2.9 -0.3 -0.2 0.1 0.2 2.5 0.6 -0.5 2.6
Birth weight of first child 0.5 0.9 2.1 1.4 -1.1 0.8 -1.1 -0.3 0.6 0.6 -1.1 0.9
Peak expiratory flow (PEF) 1.1 2.6 8.2 1.6 2.5 -0.4 1.9 2.9 0.7 0.3 1.0 1.0
Pulse wave reflection index 1.0 1.2 5.0 -1.3 -0.4 -2.2 -0.3 -1.4 -0.5 -0.8 -0.2 -1.0
Ever highly irritable/argumentative for 2 days 0.3 0.4 1.0 -0.2 -0.4 -0.7 0.2 -0.3 0.7 -0.9 -0.4 1.0
Loud music exposure frequency 1.3 1.5 3.0 -1.7 1.5 -1.4 0.7 1.2 -0.9 0.6 1.6 -0.2
Qualifications: O levels/GCSEs or equivalent 1.5 2.4 12.1 1.3 -1.0 3.5 0.0 2.2 0.8 0.4 -0.8 0.8
Mouth/teeth dental problems: Bleeding gums 0.5 0.7 2.9 0.1 0.6 -1.0 0.6 1.7 0.0 0.9 0.8 0.3
Blood clot in the leg (DVT) 1.1 1.4 3.6 -1.2 0.0 -1.1 -0.2 1.8 -1.9 -0.3 1.2 -1.3
Medication: Paracetamol 0.6 1.1 3.0 -0.9 0.0 -1.1 -0.0 1.1 -1.7 -1.1 -0.3 -1.4
Headache pain in last month 0.6 1.0 2.2 -1.2 0.8 -0.5 0.3 -0.5 -1.4 -0.2 1.4 -1.5
Medication for cholesterol, blood pressure or diabetes 0.8 1.3 4.5 1.2 1.1 0.3 1.7 2.1 0.1 -0.9 0.5 0.4
Glaucoma (self-reported) 2.0 2.3 6.0 1.8 0.4 -1.1 -1.5 -1.8 2.5 1.4 -0.1 1.7
Gout (self-reported) 1.0 1.3 3.7 -0.3 -1.0 -1.6 -0.3 -1.4 -1.0 -1.9 -0.5 -1.1
Hypothyroidism/myxoedema (self-reported) 0.3 0.6 1.3 -0.7 0.8 0.9 1.1 -1.0 0.7 0.5 0.5 0.2
Medication: Amlodipine 0.6 0.9 2.8 0.5 -0.4 -1.1 -1.6 0.2 -0.5 -1.7 -0.7 0.3
Medication: Ventolin 100micrograms inhaler 1.9 2.5 5.4 -0.8 -1.3 -1.5 -1.7 0.5 -2.0 -2.3 -0.7 -2.1
Birth weight 0.7 1.6 4.3 -1.5 0.9 1.9 2.1 0.3 -0.7 -0.1 1.4 -0.8
Chronic bronchitis/emphysema (mother) 0.2 0.2 1.0 0.5 -0.1 -0.1 -0.4 1.0 0.1 0.3 0.3 0.7
High blood pressure (siblings) 1.5 2.1 5.8 -1.5 -0.8 -1.4 -0.3 -2.0 -1.3 -1.5 -0.1 -2.4
Forced vital capacity (FVC), Best measure 0.7 2.5 9.8 0.3 0.7 2.4 0.1 3.1 -0.0 1.6 1.8 0.5
Body fat percentage 0.6 2.3 7.2 -2.7 0.1 -1.5 -0.4 -0.5 -1.7 -0.9 0.7 -2.6
Leg fat percentage (right) 0.4 1.5 3.6 -1.9 -0.5 -1.6 -0.4 -1.4 -1.0 -0.6 -0.1 -1.9
Arm fat-free mass (right) 0.4 2.2 5.0 -1.6 1.4 2.2 -0.0 0.1 -2.1 0.6 2.2 -1.0
Exposure to tobacco smoke outside home 0.7 1.0 2.7 -1.1 -1.5 0.6 -1.2 -1.6 -0.6 -0.2 -0.6 0.2
Comparative body size at age 10 0.5 1.4 3.2 -1.1 -0.2 0.5 1.2 1.8 -1.7 -0.7 -0.7 -1.8
Number of full brothers 0.4 0.5 1.9 0.1 0.4 -1.4 1.1 -0.1 0.9 -0.2 -0.1 0.5
Worry too long after embarrassment 0.8 1.4 4.0 1.3 0.6 0.2 1.6 -0.2 1.6 2.0 1.1 0.5
Seen a psychiatrist for nerves, anxiety, tension or depression 0.3 0.4 1.4 0.5 -0.9 -0.2 -0.2 -1.2 0.8 -0.6 0.1 0.1
Wheeze or whistling in the chest in last year 1.3 2.3 4.5 -1.8 0.0 -1.5 -1.6 -1.8 -1.9 -1.2 -0.5 -2.1
Number of children fathered 0.5 0.5 2.0 -0.2 1.0 -1.0 1.4 0.4 -0.1 0.5 0.5 0.6
Reason for reducing amount of alcohol drunk: Health precaution 0.7 0.8 2.3 -1.0 0.3 -0.2 0.6 1.2 -1.2 0.2 0.1 -1.5
Age at first live birth 0.6 1.1 2.0 -1.3 1.2 -1.1 1.3 -0.0 -0.7 -1.3 0.5 -1.4
Pulse wave peak to peak time 1.5 1.8 7.3 1.9 0.2 1.6 1.0 2.7 0.3 0.4 -0.1 1.2
Health satisfaction 0.6 0.7 4.6 0.6 -2.1 -0.2 0.7 0.5 0.4 -0.0 -0.8 -0.2
Shortness of breath walking on level ground 1.5 1.8 4.4 -1.6 -1.6 -0.8 -0.9 -2.1 -1.3 -0.3 0.2 -1.8
Qualifications: College or University degree 1.1 3.4 13.8 1.0 0.2 3.7 0.4 -0.3 1.4 3.0 1.7 1.6
Eye problems/disorders: None of the above 0.9 1.1 2.8 -0.8 -1.0 1.7 -1.2 -0.4 -1.1 -1.5 -0.4 -0.4
Mouth/teeth dental problems: Loose teeth 2.7 3.2 7.2 -1.8 -2.2 -1.1 -0.2 -0.8 -2.7 -1.9 -1.6 -2.2
Emphysema/chronic bronchitis 1.3 1.5 4.4 -0.9 1.8 -1.8 -0.3 0.3 -0.2 1.0 2.1 -0.5
Medication for pain relief, constipation, heartburn 0.3 0.4 2.5 0.0 -1.6 0.5 -1.0 0.2 0.1 -0.1 -0.2 -0.0
Neck or shoulder pain in last month 0.6 0.9 2.9 -1.6 0.8 0.2 -0.6 -0.2 -1.7 0.6 0.6 -0.7
Medication: Blood pressure 0.7 1.3 5.4 -0.8 -1.5 -0.6 -2.3 -1.1 -0.3 1.0 -0.7 -0.6
Angina (self-reported) 1.1 1.5 3.9 -0.9 1.4 0.5 2.0 0.6 -0.9 0.2 1.8 -1.4
Migraine (self-reported) 1.4 1.7 6.8 1.1 -0.5 1.3 -0.4 -2.6 0.6 -0.8 -1.9 0.7
Medication: Ibuprofen 0.5 0.6 1.7 1.0 0.4 0.1 0.0 0.1 0.8 1.0 -0.7 1.3
Medication: Allopurinol 0.5 0.7 2.8 0.0 -1.2 -0.3 -0.3 -1.7 -0.7 -0.4 -0.9 -0.3
Medication: Omeprazole 1.2 1.4 3.5 -1.9 0.7 0.3 0.4 -0.1 -1.3 -1.6 0.7 -1.8
Medication: Seretide 50 evohaler 0.6 0.7 2.9 0.2 -1.5 -1.7 -0.1 0.3 0.8 -0.4 -0.1 -0.3
Mean time to correctly identify matches 1.2 2.3 7.8 2.7 -0.0 -0.3 0.5 0.6 2.8 0.8 -0.9 1.8
Heart disease (mother) 0.2 0.3 1.0 0.9 0.1 1.0 0.3 -0.1 0.3 0.5 -0.0 -0.5
Reproduciblity of spirometry measurement using ERS/ATS criteria 1.6 2.0 4.4 1.8 1.3 -1.0 0.7 1.5 2.1 1.5 0.2 1.4
Whole body fat mass 0.5 2.2 6.5 -2.5 0.7 -0.8 -0.4 -0.4 -2.0 -0.5 1.5 -2.3
Leg fat mass (right) 0.5 2.1 6.7 -2.6 0.6 -0.8 -0.2 -0.7 -2.1 -0.6 1.0 -2.2
Arm predicted mass (right) 0.4 2.2 4.7 -1.7 1.4 2.1 -0.3 -0.1 -2.2 0.7 2.2 -0.8
Pulse rate, automated reading 0.5 1.6 3.6 -1.1 0.7 1.3 0.6 0.8 -1.6 -0.8 1.8 -1.9
Alcohol intake frequency. 0.3 0.7 4.6 0.8 0.2 -0.3 -0.1 -2.1 0.7 -0.3 -0.4 0.8
Comparative height size at age 10 0.9 4.8 15.4 -1.0 2.4 3.3 -0.0 3.9 -1.4 1.8 2.1 -0.7
Number of full sisters 1.0 1.2 2.7 -1.1 -1.0 -1.6 -0.8 -1.0 -1.2 -1.2 -0.8 -0.5
Suffer from ‘nerves’ 1.4 2.2 6.6 2.0 -2.6 0.8 0.4 -1.3 1.7 0.4 -1.2 1.4
Overall health rating 0.4 0.8 2.2 -0.9 0.2 -1.5 0.3 -0.2 -0.1 1.3 0.9 -1.3
Chest pain or discomfort 0.4 0.5 1.2 -1.0 0.2 1.1 -0.1 -0.3 -1.0 0.4 0.0 -1.0
Had major operations 1.0 1.2 6.2 -0.5 2.5 0.1 0.5 0.9 0.0 1.3 1.2 -0.5
Age at last live birth 1.4 2.0 5.5 -1.4 0.5 -1.0 2.0 1.1 -1.2 -2.3 -0.6 -1.6
Family relationship satisfaction 0.7 0.8 4.6 0.3 -0.7 -0.3 2.1 0.7 -0.4 -1.0 0.5 0.3
Leg pain on walking 1.4 1.7 3.5 -1.8 1.6 -1.7 -0.7 0.2 -1.9 -0.5 0.9 -1.3
Qualifications: NVQ or HND or HNC or equivalent 0.3 0.4 2.0 -1.4 -0.6 -0.4 -0.4 -0.2 -0.6 0.6 0.2 -0.6
Commuting to job workplace: Car/motor vehicle 1.4 1.7 7.5 1.1 0.8 2.7 1.5 1.4 0.9 -0.4 -0.4 -0.2
Illness, injury, bereavement, stress in last 2 years 0.9 1.1 3.8 0.6 0.2 -1.0 -1.1 -2.0 -0.2 -1.7 -0.2 -0.5
Medication: Aspirin 0.6 0.8 1.4 -0.9 1.2 0.1 0.9 -1.2 -0.5 -0.2 0.9 -1.2
Supplements: Vitamin C 2.4 2.9 6.3 2.5 -0.3 2.1 -1.4 -1.0 2.1 1.8 -0.6 1.9
Knee pain experienced in last month 0.6 1.0 2.1 -1.0 -0.8 0.2 -1.2 0.1 -1.5 -1.0 -1.3 -0.9
Hypertension (Self-reported) 0.3 0.7 3.2 -0.0 0.1 -1.1 -0.8 -1.8 -0.3 0.3 0.8 -0.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 2.2 2.6 7.9 -0.9 2.8 1.4 0.9 -0.6 0.0 2.4 2.4 -0.6
Illnesses of father: Heart disease 0.6 0.8 3.2 -1.1 0.2 0.9 0.3 -0.7 -1.8 -0.2 0.8 -1.0
Illnesses of siblings: Diabetes 1.1 1.4 3.7 -0.4 -0.5 -0.8 0.6 1.1 -1.4 -1.8 -1.0 -1.9
Smoking status: Previous 0.6 0.9 2.5 -1.1 0.7 0.3 -0.0 0.9 -1.2 -0.9 0.5 -1.6
Forced expiratory volume in 1-second (FEV1), predicted 0.6 1.2 3.6 -0.6 0.4 0.9 0.9 1.6 -1.4 -0.4 1.9 -0.5
Whole body fat-free mass 0.5 2.6 6.3 -1.3 1.9 2.5 0.2 0.4 -2.1 0.6 2.5 -0.7
Leg fat-free mass (right) 0.6 3.0 6.8 -2.0 1.9 2.1 0.4 0.6 -2.6 -0.1 2.4 -1.4
Arm fat percentage (left) 0.5 2.2 6.6 -2.6 0.9 -1.0 0.1 -0.3 -1.9 -0.5 1.1 -2.4
Average weekly red wine intake 0.5 0.8 2.2 -0.8 -0.2 -1.2 0.2 1.4 -0.5 0.3 1.5 -0.6
Handedness (chirality/laterality): Left-handed 0.4 0.5 1.6 0.6 -0.5 0.3 -1.0 -0.3 0.4 -0.7 -1.2 0.3
Mood swings 0.4 0.7 2.2 -0.7 -1.2 -0.1 -0.7 -1.0 -0.0 1.5 -0.7 0.4
Loneliness, isolation 0.9 1.3 4.1 0.1 -2.0 0.8 0.3 0.9 -1.1 -1.0 -1.2 -1.5
Long-standing illness, disability or infirmity 1.1 1.6 4.3 -1.6 -0.3 1.6 -0.2 -0.5 -2.1 -0.3 1.1 -1.9
Ever had bowel cancer screening 0.3 0.3 0.7 0.4 0.4 0.5 -0.8 0.6 0.8 0.4 -0.7 0.1
Diabetes diagnosed by doctor 1.5 2.5 6.6 -1.2 -0.5 -0.7 -1.1 -1.9 -2.3 -2.6 -0.6 -1.8
Ever had stillbirth, spontaneous miscarriage or termination 0.7 0.7 1.6 -0.1 0.2 1.3 -1.2 0.8 0.5 1.3 0.7 0.5
Friendships satisfaction 0.7 0.8 3.8 0.5 0.7 -0.7 1.9 0.5 -0.3 -0.4 1.2 -0.5
Qualifications: nursing, teaching 0.5 0.8 3.3 -0.3 0.8 1.1 0.3 0.8 -0.2 0.5 1.8 -0.9
Commuting to job workplace: Walk 0.9 1.0 4.0 -0.3 -0.8 -2.0 -0.2 0.1 -0.3 -1.7 -0.9 -0.6
Eye problems/disorders: Cataract 1.3 1.5 4.7 -0.5 0.1 -1.2 2.2 1.5 -1.3 -0.4 0.3 -1.7
Mouth/teeth dental problems: Mouth ulcers 0.7 1.0 3.7 -0.6 0.3 0.9 -0.8 -0.1 -1.0 1.9 1.7 0.1
Medication for cholesterol 1.4 2.2 12.8 -0.8 0.2 1.7 0.8 3.6 -0.5 0.9 -1.2 -0.5
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.7 0.9 2.5 0.5 -1.6 0.4 -0.8 -0.7 -0.8 -1.1 -1.3 -0.6
Back pain experienced in last month 1.1 1.6 6.0 1.0 -2.4 -0.6 0.0 -1.0 0.3 -0.9 -2.3 0.5
Mineral and other dietary supplements 1.6 2.1 5.9 1.8 0.4 -1.3 -0.3 -1.8 2.2 0.4 -0.4 2.4
Breast cancer (self-reported) 0.4 0.5 1.9 0.3 0.3 -1.4 -0.6 0.5 -0.2 -0.9 0.1 -0.7
Asthma (self-reported) 0.6 1.1 3.4 -1.0 -0.8 0.2 -1.8 -0.5 -1.4 -1.4 -0.3 -1.1
Osteoporosis (self-reported) 1.7 2.2 5.1 -0.8 1.7 -0.8 2.3 2.0 -0.7 1.2 2.0 -0.6
Osteoarthritis (self-reported) 1.9 2.5 5.3 -2.3 -0.5 1.3 -2.3 -2.3 -1.6 -0.3 -0.4 -1.2
Medication: Aspirin 0.5 0.7 1.8 -0.4 1.1 0.1 1.1 -1.3 -0.4 -0.1 0.8 -0.8
Medication: Gliclazide 0.6 0.7 2.2 0.9 -0.7 1.5 -0.7 -0.6 -0.0 0.9 -0.8 0.2
Illnesses of father: None of the above (group 1) 1.0 1.2 3.8 1.3 0.6 -0.4 -0.3 1.1 2.0 1.3 0.1 1.3
Smoking status: Current 1.8 2.8 8.0 -0.5 -1.4 -2.8 -1.6 -1.7 -0.4 -1.9 -2.4 0.4
Forced expiratory volume in 1-second (FEV1), predicted percentage 1.1 2.3 4.5 1.4 1.5 -0.5 1.5 2.1 1.2 1.7 1.7 1.6
Whole body water mass 0.5 2.7 6.9 -1.4 2.0 2.6 0.2 0.4 -2.0 0.7 2.5 -0.7
Leg predicted mass (right) 0.5 2.9 6.8 -2.0 1.9 2.1 0.3 0.6 -2.6 -0.1 2.4 -1.3
Arm fat mass (left) 0.5 2.0 5.2 -2.3 1.4 -0.2 0.1 -0.5 -1.9 -0.5 1.6 -2.1
Number of self-reported non-cancer illnesses 0.8 1.4 4.0 -1.6 1.1 -0.1 0.2 -2.0 -1.0 -0.4 1.3 -1.6
Average weekly champagne plus white wine intake 3.1 4.2 11.5 -0.4 3.3 1.5 3.1 1.5 0.3 0.9 3.4 -1.0
Miserableness 0.4 0.7 2.4 0.4 -1.0 0.9 -0.9 -0.2 0.2 1.0 -1.6 0.5
Guilty feelings 0.2 0.3 1.4 -0.4 0.8 -0.3 1.2 0.5 -0.1 -0.5 0.1 -0.5
Wears glasses or contact lenses 0.5 0.6 2.0 0.6 -0.2 -1.4 0.8 1.2 0.5 0.7 0.5 -0.2
Ever taken oral contraceptive pill 1.1 1.2 2.8 1.5 -0.7 0.8 0.2 1.0 1.2 -0.6 -1.7 1.3
Hearing aid user 0.5 0.6 2.9 0.4 0.6 1.7 0.9 1.0 0.2 0.4 0.0 0.2
Mother’s age at death 1.4 1.7 5.0 2.2 -1.0 -0.4 1.3 0.6 1.7 -0.7 -1.8 0.9
Financial situation satisfaction 0.3 0.3 2.0 -0.3 -0.1 0.1 0.4 0.1 0.0 1.4 0.8 0.1
Tinnitus: Yes, now most or all of the time 1.3 1.5 6.3 1.2 0.3 2.5 -0.4 0.7 1.2 1.2 0.0 1.4
Commuting to job workplace: Public transport 0.6 0.7 3.3 -1.3 -0.3 -1.0 0.2 -1.8 -0.4 -0.1 0.6 -0.3
Eye problems/disorders: Glaucoma 2.0 2.4 6.4 2.3 0.2 -1.2 -0.9 -1.4 2.5 1.1 -0.3 2.0
Medication: Blood pressure 0.7 1.4 5.1 0.7 1.1 -1.4 1.1 -1.4 0.8 -0.0 2.3 -0.0
Pain type(s) experienced in last month: Hip pain 0.3 0.3 1.3 -0.2 0.8 -1.1 0.2 0.3 -0.1 0.2 0.7 -0.5
Supplements: Fish oil (including cod liver oil) 1.4 1.8 4.5 -1.4 -1.5 0.3 -1.6 0.6 -2.1 -1.0 -0.1 -1.9
High cholesterol (Self-reported) 0.2 0.4 0.9 -0.4 -0.7 -0.8 0.9 -0.9 -0.1 -0.4 0.2 -0.6
Medication: Bendroflumethiazide 0.4 0.6 2.6 -0.3 -1.1 0.0 -1.6 -0.9 0.2 0.8 0.2 -0.4
Medication: Paracetamol 0.5 0.7 2.6 -0.9 0.4 -0.8 -0.2 0.6 -1.6 -0.8 -0.2 -1.1
Medication: Lisinopril 0.3 0.4 1.7 0.5 -1.3 -0.1 -1.1 -0.7 0.3 0.2 -0.3 -0.4
Medication: Atorvastatin 0.5 0.6 3.6 -0.1 -0.2 -0.8 -0.5 -1.9 0.2 0.9 0.3 0.3
Illnesses of father: High blood pressure 0.6 0.7 1.4 0.9 -1.2 0.1 0.9 0.2 1.1 -0.2 -1.1 0.9
Alcohol drinker status: Never 0.2 0.2 0.8 -0.5 -0.3 0.9 -0.3 -0.6 -0.1 -0.5 -0.4 0.0
Ever smoked 1.1 1.9 4.1 -1.2 -0.7 -0.9 -1.0 0.3 -2.0 -2.0 -1.3 -1.8
Basal metabolic rate 0.4 2.4 5.6 -1.6 1.8 2.2 0.2 0.3 -2.1 0.5 2.4 -1.0
Leg fat percentage (left) 0.6 2.3 5.1 -2.3 -1.1 -1.7 -0.9 -1.5 -1.4 -1.1 -0.2 -2.3
Arm fat-free mass (left) 0.3 1.7 4.8 -1.1 1.1 2.2 -0.4 -0.7 -1.5 0.6 2.0 -0.8
Number of operations (self-reported) 0.9 1.4 5.4 -0.2 2.3 0.4 0.8 1.2 -0.3 1.0 1.9 -0.7
Average weekly beer plus cider intake 0.7 1.0 3.9 -0.4 -0.1 0.6 -2.0 -0.9 -0.1 -1.4 -1.4 0.5
Irritability 0.4 0.6 2.0 -0.8 0.5 -0.1 0.4 0.5 -0.4 1.4 1.4 -0.2
Risk taking 2.0 2.9 7.7 -2.1 -0.1 1.0 -2.8 -2.4 -2.0 -0.0 1.6 -0.9
Ever had prostate specific antigen (PSA) test 1.0 1.2 3.4 1.9 -0.5 -0.6 1.6 1.5 1.1 0.5 -0.4 0.1
Fractured/broken bones in last 5 years 0.5 0.6 2.6 -0.2 0.9 0.7 -1.6 0.3 -0.6 -0.5 1.0 -0.2
Age started oral contraceptive pill 2.1 2.6 9.2 -1.5 0.2 -1.6 0.4 -0.6 -1.8 -2.3 0.3 -3.0
Diastolic blood pressure, automated reading 1.4 4.2 9.9 -2.5 0.9 -2.8 1.0 0.8 -1.5 0.3 3.1 -3.1
Ever depressed for a whole week 1.0 1.2 2.9 1.5 -1.0 -1.5 1.7 -0.7 1.1 -0.8 -0.5 0.5
Unable to work because of sickness or disability 0.4 0.6 2.5 -1.0 1.2 -0.3 0.0 -0.3 -0.0 -0.1 1.6 -0.3
Commuting to job workplace: Cycle 1.1 1.3 4.0 0.2 0.4 0.5 1.5 1.9 0.7 2.0 0.3 1.1
Myopia 0.7 1.0 2.8 -1.0 0.2 -0.2 0.4 1.0 -1.1 -0.9 1.5 -1.7
Vascular/heart problems diagnosed by doctor 0.3 0.8 3.7 -0.1 -0.2 1.2 0.3 1.9 -0.1 -0.5 -1.1 0.7
Cholesterol lowering medication 1.3 2.0 4.8 -1.0 0.3 -2.2 0.7 -1.0 -1.6 -1.4 1.4 -2.0
Medication: Omeprazole (e.g. Zanprol) 3.0 3.7 9.0 -2.9 1.7 -0.9 1.3 0.3 -2.1 -1.5 1.9 -3.0
Pain experienced in last month 0.1 0.2 0.6 0.4 -0.1 -0.5 0.5 0.4 0.5 -0.8 0.5 -0.1
Supplements: Calcium 0.7 0.7 2.1 -0.9 -0.3 -0.8 0.5 -0.4 -0.8 -1.4 0.5 -1.4
Basal cell carcinoma (self-reported) 0.8 0.9 2.3 0.5 -0.9 1.5 -0.7 0.8 0.2 0.8 -1.2 1.3
Heart attack/myocardial infarction (self-reported) 0.7 0.9 2.8 -1.2 0.4 -0.6 -0.0 -0.8 -1.2 -1.1 -0.5 -1.7
Deep venous thrombosis (DVT) (self-reported) 1.4 1.8 4.3 -1.5 0.2 -1.2 -0.2 2.1 -1.9 0.1 1.5 -1.3
Heart disease (siblings) 0.8 1.0 2.8 -0.5 -0.4 -1.3 0.4 -0.9 -1.1 -1.7 0.6 -1.3
Alcohol drinker status: Previous 1.7 1.9 7.8 -0.8 0.7 -1.9 0.8 -0.9 -1.4 -2.8 0.2 -1.4
Pack years of smoking 0.7 1.0 2.7 -0.5 -0.2 -0.4 -1.6 -1.6 -0.7 -1.3 -0.7 -0.8
Impedance of whole body 0.3 1.5 5.3 0.5 -0.6 -1.6 -0.0 2.3 1.8 0.2 -1.1 0.6
Leg fat mass (left) 0.7 2.6 8.1 -2.8 0.2 -1.0 -0.5 -0.8 -2.4 -0.9 0.9 -2.5
Arm predicted mass (left) 0.3 1.6 4.3 -1.3 0.9 2.1 -0.5 -0.5 -1.8 0.5 1.7 -0.8