Hub : Genes

MTUS1

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.2800	0.0430	0.0e+00	0.138	0.192	0.211	0.150	0.174	1.8e-16	7.3e-23	3.2e-25	7.3e-18	1.2e-20
2	GTEx	Artery Aorta	0.3510	0.0700	2.6e-06	0.105	NA	0.189	NA	0.167	2.2e-06	NA	1.2e-10	NA	1.7e-09
3	GTEx	Brain Caudate basal ganglia	0.4140	0.1190	5.4e-03	-0.010	NA	0.013	NA	0.042	8.6e-01	NA	1.3e-01	NA	2.4e-02
4	METSIM	Adipose	0.0707	0.0230	6.2e-04	0.050	0.021	0.057	0.046	0.061	4.5e-08	3.4e-04	6.7e-09	1.8e-07	1.9e-09
5	NTR	Blood	0.1593	0.0242	0.0e+00	0.113	0.099	0.154	0.136	0.149	2.5e-34	3.6e-30	2.2e-47	9.8e-42	1.0e-45
6	ROSMAP	Brain Pre-frontal Cortex	0.3538	0.0474	0.0e+00	0.161	0.231	0.286	0.258	0.271	3.3e-20	2.8e-29	6.1e-37	5.0e-33	8.1e-35
7	TCGA	Head and Neck Squamous Cell Carcinoma	0.0434	0.0207	6.3e-03	0.002	0.019	0.005	NA	0.003	2.0e-01	3.1e-03	7.9e-02	NA	1.2e-01
8	TCGA	Kidney Renal Clear Cell Carcinoma	0.1758	0.0442	7.4e-09	0.105	0.077	0.110	NA	0.119	7.3e-12	4.9e-09	2.1e-12	NA	2.5e-13
9	TCGA	Brain Lower Grade Glioma	0.0836	0.0272	1.8e-07	0.069	0.066	0.064	NA	0.086	3.1e-08	5.9e-08	8.0e-08	NA	5.4e-10

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Bipolar Disorder (2018)	1.5	2.4	6.1	2.5	-0.4	1.5	0.6	-0.1	2.2	1.1	-0.9	2.3
Bipolar Disorder or Schizophrenia	1.3	3.1	10.4	3.2	-0.6	1.0	1.0	-0.8	2.4	0.6	-1.0	2.7
Depressed Affect (Nagel 2018)	0.3	0.7	3.0	0.0	-0.7	1.7	0.1	0.1	0.1	1.7	-0.1	0.3
Depression (Nagel 2018)	0.3	0.5	1.5	0.1	-0.4	0.9	0.2	1.0	0.5	1.2	0.8	0.2
Intelligence (Savage-Jansen 2018)	0.6	1.8	5.4	0.6	0.8	2.3	2.3	1.4	0.9	0.0	0.8	0.9
Neuroticism (Nagel 2018)	0.6	1.5	7.8	0.3	0.0	1.2	0.6	-0.0	1.1	2.8	1.2	1.0
Schizophrenia (2018)	0.6	1.2	4.8	2.2	-0.5	0.1	0.8	-1.0	1.2	-0.0	-0.6	1.6
Schizophrenia vs Biploar Disorder	0.5	0.6	2.2	-0.4	0.3	-1.5	-0.6	-0.9	-0.1	-1.0	-1.0	0.4
Worry (Nagel 2018)	0.7	1.5	4.6	0.9	-0.8	0.4	0.5	-0.3	2.2	2.1	0.6	1.6
Alzheimer’s Disease (in mother)	0.4	0.5	2.0	-0.8	-0.4	0.0	-1.2	-1.4	-0.6	-0.1	0.3	0.1
Alzheimer’s Disease (in father)	0.3	0.3	0.8	-0.3	0.8	0.7	-0.0	-0.3	-0.5	-0.4	0.4	-0.9
Alzheimer’s Disease (including proxy)	0.7	1.0	2.5	-1.1	-0.0	-0.1	-1.3	-1.6	-1.2	-1.1	0.8	-0.6
Crohns Disease (2017)	0.6	1.3	3.6	1.3	0.9	0.2	0.6	-1.4	1.6	0.8	0.1	1.9
Irritable Bowel Disease (IBD)	0.7	1.6	6.5	1.3	2.5	1.4	0.7	-0.2	0.7	0.6	1.1	1.3
Ulcerative Colitis (UC)	0.8	1.5	6.9	0.7	2.6	1.4	0.3	0.7	-0.4	0.6	1.8	0.4
Major Depression (MDD)	1.6	2.0	4.9	1.3	-1.5	-0.0	-0.8	1.1	1.1	2.2	-1.1	2.2
Reaction Time	1.3	2.5	7.4	2.4	0.2	-1.0	1.1	1.3	2.7	0.5	-0.8	2.1
Verbal and Numeric Reasoning (VNR)	0.5	1.1	6.4	0.8	-0.9	2.5	0.8	0.6	0.8	-0.2	0.4	0.7
Breast Cancer	0.6	1.5	2.3	-1.2	1.5	-1.2	0.9	-1.4	-1.1	-0.8	1.4	-1.3
Ovarian Cancer	1.0	1.3	3.9	-0.5	1.8	0.1	1.0	0.8	-0.2	1.6	2.0	-0.4
Prostate Cancer	0.3	0.4	1.4	-0.9	0.5	1.2	0.2	-0.8	-0.0	0.4	0.1	0.1
Age at First Birth	0.5	0.8	2.2	-0.0	1.3	1.3	1.5	0.6	0.4	0.3	1.0	0.1
Bipolar Disorder (2011)	2.1	2.0	3.6	1.7	-1.9	1.2	-1.2	-1.6	1.2	-0.5	-1.4	1.6
Body Mass Index (BMI) (2010)	1.7	2.3	5.7	-1.0	1.2	-0.9	2.3	2.4	-1.0	-0.4	1.9	-1.3
Coronary Artery Disease (CAD)	1.4	1.6	5.6	1.2	-1.4	0.1	-1.0	-0.6	0.0	-2.0	-2.4	0.6
Crohns Disease (2012)	0.8	1.3	2.6	1.0	-1.4	0.5	-0.3	-1.2	1.6	-0.2	-1.6	1.3
Mean Putamen Volume	1.1	1.3	3.5	-1.9	0.9	1.5	0.7	-0.4	-1.3	-0.9	0.5	-1.1
Fasting Glucose	2.1	2.5	4.3	-0.8	-2.0	-0.1	-2.1	-1.6	-2.0	-1.9	-0.6	-1.8
HbA1C	0.4	0.4	2.2	-0.2	-0.1	0.4	-0.2	-0.4	0.8	1.5	0.7	-0.0
HDL Cholesterol	0.2	0.3	1.3	-0.9	0.7	0.0	-0.1	-0.1	0.5	1.1	0.1	-0.4
LDL Cholesterol	0.8	1.2	4.4	-0.4	1.7	0.7	0.0	1.4	-0.7	0.5	2.1	0.2
Lupus	0.6	0.9	3.7	-0.2	-1.0	-0.4	-1.6	-1.9	0.0	-0.4	-0.1	0.3
Neuroticism (2016)	0.5	0.7	2.6	0.3	-1.6	1.5	0.1	-0.8	0.8	0.3	-0.5	-0.3
Primary Biliary Cirrhosis	0.5	0.6	2.0	0.3	-0.4	-1.0	-1.1	-0.7	-0.8	-1.4	-0.2	0.1
Rheumatoid Arthritis	1.8	2.5	8.2	2.9	0.0	0.3	2.0	-0.4	2.6	-1.1	-0.8	1.3
Schizophrenia (2014)	1.0	2.1	7.5	2.7	-0.8	0.7	1.0	-0.4	2.0	-0.2	-1.3	1.9
Triglycerides	0.5	0.8	2.9	-0.0	0.1	-1.2	0.1	1.3	-1.7	-0.6	0.8	0.2
Type 2 Diabetes (T2D) (2012)	0.5	0.6	2.0	0.4	-0.1	0.1	0.5	-0.5	1.4	0.9	-0.8	0.9
Ulcerative Colitis	0.4	0.5	1.4	0.8	0.8	0.8	1.2	0.7	-0.0	-0.2	0.8	0.1
Blood Eosinophil Count	0.1	0.7	3.7	-0.2	0.1	-0.7	0.8	1.9	0.1	0.2	-1.1	0.4
Blood Platelet Count	0.1	0.7	3.1	-0.1	0.4	0.4	1.3	1.8	-0.5	-0.3	0.7	0.2
Blood Red Count	0.1	0.6	2.2	1.0	-0.5	-1.5	0.9	-0.2	0.3	0.3	-0.8	-0.3
Blood White Count	0.1	0.7	2.7	0.2	-0.4	-1.6	0.2	-0.1	0.2	-0.4	-1.5	0.7
Heel T-Score	0.5	4.0	11.0	3.3	0.3	-1.4	-0.6	-0.6	3.1	1.6	0.1	3.1
BMI	0.4	2.4	5.8	-2.1	0.0	-1.2	-0.3	-1.3	-2.4	-1.6	0.4	-2.3
Height	0.6	11.1	26.4	-3.8	1.3	4.7	0.6	5.1	-3.7	1.9	2.7	-3.1
Waist Hip Ratio (WHR)	0.6	2.6	12.0	-1.1	0.7	-1.3	0.9	1.7	-0.8	-3.5	-0.7	-1.7
Systolic Blood Pressure	0.4	1.9	7.1	-1.3	1.0	-2.1	0.2	-1.1	-0.9	0.2	2.7	-1.1
Smoking Status	0.8	1.9	5.6	-1.4	-0.3	-1.9	-1.0	-1.2	-1.1	-2.4	-1.5	-0.5
Allergy or Eczema	0.1	0.4	1.6	0.5	0.2	-0.1	-0.5	-1.1	1.3	0.4	0.2	0.2
Cardiovascular Disease	0.2	0.5	1.9	-0.2	0.3	-0.6	-0.6	-1.4	-0.1	0.6	1.2	-0.1
Hypothyroidism (self reported)	0.2	0.4	1.7	-0.3	0.5	0.8	1.3	-0.7	0.7	0.5	-0.1	0.4
Respiratory disease	1.1	2.4	5.7	-2.0	-0.7	-0.9	-1.0	-0.5	-2.2	-2.1	-0.3	-2.4
Type 2 Diabetes (T2D) (2018)	1.8	3.4	8.1	-0.9	-1.8	-1.8	-1.4	-1.8	-2.2	-2.9	-2.0	-1.1
Lung FEV1/FVC ratio	2.3	11.9	34.5	5.4	2.9	-1.7	0.7	-1.6	5.1	1.4	-1.3	5.9
Lung FVC	0.2	0.9	2.1	-0.4	0.6	-1.2	0.2	1.4	-0.3	1.5	1.3	0.1
Neuroticism	0.3	0.8	4.4	0.2	-0.0	0.9	0.7	-0.1	0.8	2.1	0.5	1.0
Chronotype (morning person)	0.9	2.1	7.6	0.9	0.2	1.1	2.7	1.7	1.3	2.1	0.1	0.3
Hair Pigment	0.0	0.5	1.5	-0.7	-0.0	0.9	-0.2	1.2	-0.6	-0.0	0.8	-0.7
Tanning	0.0	0.5	2.2	0.0	-0.3	0.6	0.0	1.5	0.4	0.8	-0.8	0.6
Hand grip strength (left)	0.6	1.5	8.1	-0.3	-0.9	-0.4	-0.4	-1.1	-1.2	-2.8	-1.2	-0.4
Number of treatments/medications taken	0.4	0.6	3.7	-0.0	0.1	-0.7	0.3	-1.9	-0.0	0.7	0.9	-0.4
Average weekly spirits intake	0.4	0.5	3.0	-0.1	-0.2	0.1	0.1	1.7	-0.7	0.1	0.2	-0.9
Sensitivity / hurt feelings	0.6	1.0	2.4	-0.5	1.1	-0.4	1.6	0.4	-0.1	1.5	1.5	-0.4
Frequency of depressed mood in last 2 weeks	0.4	0.5	2.1	0.1	-1.4	-0.1	0.2	0.6	0.2	1.4	0.0	-0.2
Hearing difficulty/problems: Yes	0.1	0.2	1.0	-0.1	0.3	-0.4	0.4	0.0	-0.5	1.0	0.2	-0.1
Relative age of first facial hair	0.4	0.8	2.6	0.1	-1.2	0.2	0.7	-1.2	-0.1	-1.6	-1.2	-0.1
Other serious medical condition/disability diagnosed by doctor	1.5	2.0	5.1	-0.1	2.2	-0.1	2.3	0.8	0.8	1.2	2.3	0.1
Ever used hormone-replacement therapy (HRT)	1.7	2.1	4.4	1.4	-2.0	-0.2	-2.1	-1.8	1.2	0.2	-1.8	0.9
Ever had hysterectomy (womb removed)	1.6	1.9	7.5	2.7	0.0	1.0	-0.3	-0.6	2.1	0.1	0.3	1.8
Systolic blood pressure, automated reading	0.6	1.8	7.6	-1.4	0.5	-2.8	0.0	-1.3	-0.7	-0.2	1.3	-1.5
Eye problems/disorders: Diabetes related eye disease	0.4	0.5	2.0	0.9	0.1	0.3	-0.1	-1.4	1.0	0.2	-0.1	0.7
Angina	0.7	0.9	3.5	-0.6	0.9	0.6	1.9	0.6	-0.6	-0.0	1.3	-1.1
Medication for hormone replacement therapy	3.5	3.9	9.5	2.4	-0.4	-1.0	-1.5	-2.2	2.6	2.0	-0.7	3.1
Vitamin and mineral supplements	0.8	1.2	4.7	-0.4	1.2	-2.2	1.7	0.8	0.1	-0.1	0.3	0.5
Supplements: Zinc	2.1	2.3	4.2	0.5	2.0	1.9	1.1	1.6	0.8	2.0	1.9	0.6
Medication: Co-codamol	0.7	0.8	1.6	-1.1	-1.2	-1.3	0.4	0.2	-1.2	-0.3	0.5	-0.8
Medication: Metformin	1.0	1.4	1.8	-0.6	-1.0	-1.3	-1.2	-1.3	-1.1	-1.4	-1.2	-1.1
Diabetes (father)	1.0	1.3	4.8	0.3	-1.4	0.5	-0.3	-0.3	-1.1	-2.2	-1.7	-0.6
Diabetes (mother)	0.3	0.4	1.5	-0.1	-0.0	-0.9	-0.8	-1.2	-0.1	-0.9	-0.1	0.3
Severe depression (siblings)	0.4	0.5	3.8	0.4	-0.2	1.9	0.2	-0.5	0.0	0.3	-0.1	0.4
Pack years adult smoking proportion	0.4	0.7	1.8	-0.6	0.0	-0.2	-1.3	-1.2	-0.7	-1.0	-0.5	-0.7
Impedance of leg (right)	0.4	1.8	5.9	1.2	-0.8	-1.8	-0.2	1.2	2.4	0.6	-1.2	1.4
Leg fat-free mass (left)	0.6	3.1	6.8	-2.0	2.2	1.9	0.7	0.7	-2.6	0.2	2.4	-1.4
Trunk fat percentage	0.6	2.4	7.7	-2.8	0.6	-1.2	-0.1	0.0	-1.6	-1.0	1.0	-2.7
Hand grip strength (right)	0.3	0.8	4.5	-0.6	-0.1	0.5	0.2	-0.2	-1.4	-2.1	-0.3	-0.4
Townsend deprivation index at recruitment	1.4	1.9	5.8	-2.4	-0.4	-0.8	-1.3	-0.3	-1.9	-1.3	-0.3	-1.9
Current tobacco smoking	1.6	2.7	9.1	-1.0	-1.1	-3.0	-1.6	-1.6	-0.8	-1.9	-1.8	-0.1
Average weekly fortified wine intake	0.2	0.3	1.2	-0.2	0.4	0.1	0.6	0.6	-0.2	-0.5	0.5	-1.1
Maternal smoking around birth	0.5	0.7	1.8	1.2	-0.1	-1.0	-0.3	-0.4	1.3	0.7	0.1	1.2
Fed-up feelings	0.2	0.3	0.7	-0.8	-0.8	-0.1	-0.1	0.0	-0.8	0.8	-0.2	-0.4
Frequency of unenthusiasm / disinterest in last 2 weeks	0.2	0.3	1.4	-0.4	-0.9	-0.2	-0.0	-0.1	0.2	1.2	0.4	-0.1
Relative age voice broke	0.8	1.2	4.5	-0.8	0.4	-1.3	1.1	-1.1	-0.2	-2.1	0.2	-1.1
Taking other prescription medications	0.2	0.3	1.2	0.0	0.1	-0.2	0.1	-1.0	-0.2	-1.1	0.6	-0.7
Age when periods started (menarche)	0.2	0.5	1.8	-0.4	0.0	0.1	1.0	-1.4	-0.2	-0.7	0.6	-0.6
Bilateral oophorectomy (both ovaries removed)	0.7	0.8	3.3	0.5	0.6	0.6	-0.0	-1.8	1.4	-0.4	0.7	0.4
Heel bone mineral density (BMD) T-score, automated (left)	0.5	1.1	2.3	1.3	0.3	-1.5	-0.6	1.4	0.8	1.2	-0.2	1.2
Tinnitus: Yes, but not now, but have in the past	2.0	2.1	4.7	1.7	-1.8	-0.6	-2.2	-0.1	0.8	1.0	-1.8	1.7
Qualifications: CSEs or equivalent	0.5	0.7	1.7	-0.7	0.2	-0.8	-1.3	-1.3	-0.5	-0.5	0.1	1.1
Serious illness, injury or assault to yourself	1.8	2.2	6.1	-1.8	1.6	-0.7	1.9	1.2	-1.2	-0.1	2.5	-0.8
High blood pressure	0.3	0.9	4.2	0.1	-0.0	-1.3	-0.8	-2.0	-0.1	0.7	1.0	-0.5
Hayfever, allergic rhinitis or eczema	0.2	0.4	0.9	0.2	-0.2	0.8	-0.8	-0.8	0.9	0.7	0.2	0.0
Multivitamins +/- minerals	0.3	0.4	1.5	0.6	-0.9	1.2	-0.5	0.3	0.5	-0.2	-0.2	0.0
Stomach or abdominal pain in last month	0.4	0.5	3.2	0.3	-0.3	-0.3	-1.8	0.2	-0.7	-0.3	-0.7	0.0
Supplements: Glucosamine	0.9	1.2	5.2	-1.3	-0.6	2.3	0.7	0.1	-1.0	-0.2	-0.5	-1.3
Diverticular disease/diverticulitis (self-reported)	1.8	2.2	6.5	-0.1	2.5	-0.9	2.0	1.5	-1.0	0.0	2.3	0.0
Medication: Atenolol	0.9	1.1	2.3	-1.4	-0.7	-0.9	1.1	-1.3	-0.6	0.5	0.8	-1.5
Medication: Levothyroxine sodium	0.2	0.3	0.9	-0.0	-0.1	0.9	0.3	-0.5	1.0	0.8	-0.1	0.2
Sitting height	0.3	2.3	5.4	-0.4	1.9	2.0	0.2	2.2	-0.6	1.4	2.3	0.4
Chronic bronchitis/emphysema (father)	0.6	0.8	2.5	-1.6	-0.4	-0.3	0.4	0.0	-0.9	-0.6	-0.0	-1.6
High blood pressure (mother)	1.5	2.2	8.9	-0.4	1.6	-3.0	0.9	0.5	-0.8	-1.0	2.0	-1.1
Body mass index (BMI)	0.5	2.0	4.8	-2.2	0.3	-0.3	-0.4	-1.8	-2.1	-0.9	0.8	-2.0
Impedance of leg (left)	0.4	1.9	5.0	0.9	-1.7	-1.9	-0.9	0.9	2.2	-0.2	-1.6	1.1
Leg predicted mass (left)	0.6	3.1	6.4	-2.0	2.3	2.0	0.7	0.7	-2.5	0.3	2.4	-1.3
Trunk fat mass	0.6	2.5	8.3	-2.9	0.9	-0.4	0.0	0.1	-2.0	-0.6	1.5	-2.5
Waist circumference	1.0	3.6	9.6	-2.9	0.4	-0.4	0.0	-0.1	-2.8	-2.4	0.6	-3.1
Number of incorrect matches in round	0.2	0.4	0.9	0.9	0.3	-0.4	0.3	0.6	0.4	-0.8	-0.8	0.4
Past tobacco smoking	0.7	1.3	3.1	1.3	-0.1	0.7	0.4	-0.6	1.6	1.8	0.4	1.7
Alcohol usually taken with meals	0.8	1.3	4.7	1.3	0.1	-0.7	-0.4	-1.0	1.2	2.2	1.0	1.1
Nervous feelings	0.6	1.1	3.3	1.1	-1.8	0.2	0.9	0.4	1.8	0.5	-0.3	1.0
Frequency of tenseness / restlessness in last 2 weeks	0.6	1.0	3.7	-0.3	-0.5	-1.3	1.0	1.9	-0.2	1.4	0.4	-0.2
Hearing difficulty/problems with background noise	0.4	0.7	2.4	-0.4	0.8	1.0	-0.2	-0.4	-0.7	1.5	1.1	-0.4
Hair/balding pattern: Pattern 2	1.7	2.1	4.8	-1.6	-1.9	1.7	-0.2	0.7	-1.9	-0.7	-0.5	-2.2
Had menopause	0.8	1.0	3.7	-0.8	-0.7	-1.5	-0.2	-0.5	-1.1	-0.1	0.2	-1.9
Had other major operations	0.7	0.9	2.3	-0.0	0.8	0.3	0.8	1.2	-0.6	-1.3	0.9	-1.5
Forced vital capacity (FVC)	0.5	1.9	6.9	-0.1	1.5	1.7	-0.0	2.6	-0.4	0.8	2.0	-0.0
Heel bone mineral density (BMD) T-score, automated (right)	0.6	1.5	3.6	1.1	0.6	-1.7	-0.6	0.9	1.1	1.6	0.1	1.9
Ever unenthusiastic/disinterested for a whole week	1.0	1.2	4.4	1.0	-2.1	-1.6	0.7	0.2	0.7	-0.4	-1.1	0.6
Qualifications: None of the above	0.9	2.0	12.6	-0.1	-0.2	-3.6	0.7	-0.7	-0.0	-1.2	-1.5	-0.7
Financial difficulties in last 2 years	0.6	0.8	1.4	-0.8	-0.5	-1.0	-1.2	-0.3	-1.2	0.6	1.2	-0.5
Mouth/teeth dental problems	0.5	0.7	2.9	0.1	0.9	1.7	0.6	0.1	1.1	0.5	0.8	0.6
Heart attack	0.7	0.8	2.6	-1.0	0.3	-0.5	-0.2	-0.8	-1.1	-1.2	-0.5	-1.6
Allergy	0.3	0.7	4.1	0.7	0.5	-0.2	2.0	0.6	0.1	-0.5	-0.8	0.5
Pain all over the body in last month	0.8	0.9	3.6	0.4	0.5	0.9	-1.0	0.0	0.7	1.9	0.8	1.0
Diabetes (self-reported)	1.6	2.5	7.5	-0.8	-0.7	-0.0	-0.9	-1.7	-2.2	-2.7	-1.2	-1.8
Hayfever/allergic rhinitis (self-reported)	0.9	1.2	3.1	-0.5	1.3	-1.4	1.2	-0.9	-0.0	-0.0	1.8	-0.9
Medication: Ramipril	0.2	0.3	0.8	0.3	-0.9	0.3	0.1	0.5	0.5	0.4	-0.7	0.7
Medication: Simvastatin	0.8	1.1	4.0	-1.3	-0.6	-0.8	0.2	-0.7	-1.1	-1.0	0.5	-2.0
Fluid intelligence score	0.3	0.5	2.1	0.6	-1.4	0.9	0.1	0.4	0.6	-0.8	0.1	0.4
Illnesses of siblings	3.6	5.0	15.7	2.6	0.4	1.8	-0.2	1.2	2.7	3.2	0.1	4.0
Neuroticism score	0.2	0.3	1.3	-0.1	-0.7	0.2	1.1	0.4	0.3	1.0	-0.0	-0.1
Weight	0.5	2.3	5.4	-2.3	1.2	0.9	-0.1	0.0	-2.3	-0.0	2.0	-1.9
Impedance of arm (right)	0.2	1.1	5.5	0.3	0.8	-0.9	0.6	2.4	1.5	0.2	-0.5	0.5
Arm fat percentage (right)	0.4	1.6	4.9	-2.2	0.7	-0.9	-0.1	-0.7	-1.5	-0.6	0.9	-2.1
Trunk fat-free mass	0.5	2.7	8.3	-0.7	2.1	2.9	0.2	0.6	-1.5	1.1	2.6	-0.2
Hip circumference	0.7	2.9	8.4	-2.9	0.7	0.4	-0.1	-0.7	-2.5	-0.7	1.8	-2.6
Time employed in main current job	0.3	0.3	1.0	0.0	-1.0	0.1	0.2	-0.6	0.0	-1.0	-0.7	-0.2
Alcohol intake versus 10 years previously	0.6	0.9	2.7	-1.0	-0.9	-1.7	-0.2	0.7	-1.1	-1.0	-0.7	-0.6
Father’s age at death	0.6	0.8	2.3	0.4	-1.5	1.1	0.9	1.0	0.4	0.7	-1.1	0.1
Worrier / anxious feelings	0.9	1.7	5.5	1.6	-0.2	0.3	1.1	0.5	2.4	2.1	0.1	0.9
Frequency of tiredness / lethargy in last 2 weeks	0.5	0.8	2.3	-1.1	-0.4	1.0	-0.5	0.9	-0.8	1.5	0.4	-0.9
Falls in the last year	0.2	0.3	1.0	-1.0	0.3	0.7	0.3	-0.3	-0.5	-0.3	-0.2	-0.3
Hair/balding pattern: Pattern 3	1.3	1.9	7.6	-0.7	2.8	-1.6	1.6	0.4	-0.9	-0.6	1.7	-0.7
Number of live births	1.4	2.0	7.9	-0.1	0.2	2.3	0.8	0.8	1.0	2.8	-0.5	1.4
Forced expiratory volume in 1-second (FEV1)	0.8	2.8	6.2	1.6	2.5	1.1	0.5	2.3	1.2	1.5	1.7	1.8
Pulse rate	0.3	0.6	3.0	0.5	-0.3	0.8	1.7	-0.6	-0.0	-0.9	0.2	-0.2
Happiness	0.8	0.9	4.5	2.1	-0.8	0.5	1.1	0.2	0.8	0.1	-0.5	0.9
Noisy workplace	1.9	2.4	5.8	-2.4	-0.6	-1.3	-0.6	1.9	-2.3	-0.3	0.0	-2.2
Qualifications: A levels/AS levels or equivalent	1.1	2.3	12.0	0.6	-0.4	3.5	0.8	2.7	-0.4	-0.5	-0.1	-0.3
Serious illness, injury or assault of a close relative in last 2 years	0.6	0.7	4.0	-0.0	-0.3	0.8	0.1	2.0	0.3	0.9	0.0	0.4
Mouth/teeth dental problems: Dentures	0.6	1.0	3.0	0.1	-0.3	-1.7	-0.3	-0.8	-0.3	-1.7	-1.3	-1.0
Asthma	0.5	1.1	3.0	-1.3	-0.7	0.4	-1.7	-0.5	-1.3	-1.2	-0.1	-1.0
Medication: Ibuprofen (e.g. Nurofen)	0.3	0.3	0.7	0.4	0.7	-0.8	0.7	0.5	0.4	0.3	-0.7	0.6
Medication: Cholesterol lowering	0.7	1.1	3.8	-0.5	-1.9	-0.5	-0.4	-1.7	-0.2	-0.6	-1.3	-0.5
Depression (self-reported)	1.0	1.2	3.5	-0.8	-1.6	1.9	-0.2	0.2	-1.0	-1.2	0.3	-1.2
Medication: Lansoprazole	2.6	3.0	16.2	0.6	1.4	1.2	0.2	0.1	1.3	4.0	1.6	1.6
Prospective memory result	0.7	0.9	2.3	1.5	-0.0	0.9	0.9	1.2	1.5	0.1	0.0	0.8
Lung cancer (father)	0.9	1.0	2.7	-1.2	0.9	-0.1	0.6	1.4	-0.7	-1.4	0.2	-1.6
Illnesses of mother	1.8	2.2	9.5	1.3	-0.5	3.1	-0.1	0.6	1.6	0.3	-1.5	1.7
Forced expiratory volume in 1-second (FEV1), Best measure	1.1	3.7	7.3	2.0	1.6	1.9	0.9	2.7	1.7	2.0	1.3	2.4
Pulse wave Arterial Stiffness index	1.3	1.5	5.2	-1.8	-0.2	-1.5	-0.8	-2.3	-0.4	-0.4	0.1	-1.3
Impedance of arm (left)	0.3	1.2	7.9	-0.1	0.4	-0.8	0.6	2.8	1.0	0.4	-0.7	0.0
Arm fat mass (right)	0.5	2.0	5.5	-2.3	1.1	-0.3	-0.0	-0.5	-1.8	-0.4	1.6	-2.1
Trunk predicted mass	0.4	2.6	8.1	-0.7	2.1	2.8	0.2	0.5	-1.5	1.0	2.5	-0.3
Standing height	0.5	5.0	14.8	-0.5	2.3	3.3	0.7	3.9	-0.6	1.9	3.0	0.1
Length of working week for main job	0.9	1.0	2.8	0.7	0.5	1.2	-0.4	-1.7	0.5	0.8	0.9	1.5
Exposure to tobacco smoke at home	0.3	0.3	1.2	-0.1	-0.4	0.4	-0.2	-1.1	-0.2	-1.0	-0.4	-0.7
Breastfed as a baby	0.3	0.4	1.3	0.0	-0.3	-0.1	-1.1	0.8	-1.1	0.4	-0.2	-0.7
Tense / ‘highly strung’	0.3	0.4	1.0	0.2	-1.0	-0.9	0.9	-0.3	1.0	-0.1	-0.4	0.2
Seen doctor (GP) for nerves, anxiety, tension or depression	0.7	1.1	6.1	1.1	-2.5	-0.2	0.1	-0.3	0.8	-0.9	-0.7	0.1
Hair/balding pattern: Pattern 4	1.0	2.5	8.5	2.9	-0.3	-0.2	0.1	0.2	2.5	0.6	-0.5	2.6
Birth weight of first child	0.5	0.9	2.1	1.4	-1.1	0.8	-1.1	-0.3	0.6	0.6	-1.1	0.9
Peak expiratory flow (PEF)	1.1	2.6	8.2	1.6	2.5	-0.4	1.9	2.9	0.7	0.3	1.0	1.0
Pulse wave reflection index	1.0	1.2	5.0	-1.3	-0.4	-2.2	-0.3	-1.4	-0.5	-0.8	-0.2	-1.0
Ever highly irritable/argumentative for 2 days	0.3	0.4	1.0	-0.2	-0.4	-0.7	0.2	-0.3	0.7	-0.9	-0.4	1.0
Loud music exposure frequency	1.3	1.5	3.0	-1.7	1.5	-1.4	0.7	1.2	-0.9	0.6	1.6	-0.2
Qualifications: O levels/GCSEs or equivalent	1.5	2.4	12.1	1.3	-1.0	3.5	0.0	2.2	0.8	0.4	-0.8	0.8
Mouth/teeth dental problems: Bleeding gums	0.5	0.7	2.9	0.1	0.6	-1.0	0.6	1.7	0.0	0.9	0.8	0.3
Blood clot in the leg (DVT)	1.1	1.4	3.6	-1.2	0.0	-1.1	-0.2	1.8	-1.9	-0.3	1.2	-1.3
Medication: Paracetamol	0.6	1.1	3.0	-0.9	0.0	-1.1	-0.0	1.1	-1.7	-1.1	-0.3	-1.4
Headache pain in last month	0.6	1.0	2.2	-1.2	0.8	-0.5	0.3	-0.5	-1.4	-0.2	1.4	-1.5
Medication for cholesterol, blood pressure or diabetes	0.8	1.3	4.5	1.2	1.1	0.3	1.7	2.1	0.1	-0.9	0.5	0.4
Glaucoma (self-reported)	2.0	2.3	6.0	1.8	0.4	-1.1	-1.5	-1.8	2.5	1.4	-0.1	1.7
Gout (self-reported)	1.0	1.3	3.7	-0.3	-1.0	-1.6	-0.3	-1.4	-1.0	-1.9	-0.5	-1.1
Hypothyroidism/myxoedema (self-reported)	0.3	0.6	1.3	-0.7	0.8	0.9	1.1	-1.0	0.7	0.5	0.5	0.2
Medication: Amlodipine	0.6	0.9	2.8	0.5	-0.4	-1.1	-1.6	0.2	-0.5	-1.7	-0.7	0.3
Medication: Ventolin 100micrograms inhaler	1.9	2.5	5.4	-0.8	-1.3	-1.5	-1.7	0.5	-2.0	-2.3	-0.7	-2.1
Birth weight	0.7	1.6	4.3	-1.5	0.9	1.9	2.1	0.3	-0.7	-0.1	1.4	-0.8
Chronic bronchitis/emphysema (mother)	0.2	0.2	1.0	0.5	-0.1	-0.1	-0.4	1.0	0.1	0.3	0.3	0.7
High blood pressure (siblings)	1.5	2.1	5.8	-1.5	-0.8	-1.4	-0.3	-2.0	-1.3	-1.5	-0.1	-2.4
Forced vital capacity (FVC), Best measure	0.7	2.5	9.8	0.3	0.7	2.4	0.1	3.1	-0.0	1.6	1.8	0.5
Body fat percentage	0.6	2.3	7.2	-2.7	0.1	-1.5	-0.4	-0.5	-1.7	-0.9	0.7	-2.6
Leg fat percentage (right)	0.4	1.5	3.6	-1.9	-0.5	-1.6	-0.4	-1.4	-1.0	-0.6	-0.1	-1.9
Arm fat-free mass (right)	0.4	2.2	5.0	-1.6	1.4	2.2	-0.0	0.1	-2.1	0.6	2.2	-1.0
Exposure to tobacco smoke outside home	0.7	1.0	2.7	-1.1	-1.5	0.6	-1.2	-1.6	-0.6	-0.2	-0.6	0.2
Comparative body size at age 10	0.5	1.4	3.2	-1.1	-0.2	0.5	1.2	1.8	-1.7	-0.7	-0.7	-1.8
Number of full brothers	0.4	0.5	1.9	0.1	0.4	-1.4	1.1	-0.1	0.9	-0.2	-0.1	0.5
Worry too long after embarrassment	0.8	1.4	4.0	1.3	0.6	0.2	1.6	-0.2	1.6	2.0	1.1	0.5
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.4	1.4	0.5	-0.9	-0.2	-0.2	-1.2	0.8	-0.6	0.1	0.1
Wheeze or whistling in the chest in last year	1.3	2.3	4.5	-1.8	0.0	-1.5	-1.6	-1.8	-1.9	-1.2	-0.5	-2.1
Number of children fathered	0.5	0.5	2.0	-0.2	1.0	-1.0	1.4	0.4	-0.1	0.5	0.5	0.6
Reason for reducing amount of alcohol drunk: Health precaution	0.7	0.8	2.3	-1.0	0.3	-0.2	0.6	1.2	-1.2	0.2	0.1	-1.5
Age at first live birth	0.6	1.1	2.0	-1.3	1.2	-1.1	1.3	-0.0	-0.7	-1.3	0.5	-1.4
Pulse wave peak to peak time	1.5	1.8	7.3	1.9	0.2	1.6	1.0	2.7	0.3	0.4	-0.1	1.2
Health satisfaction	0.6	0.7	4.6	0.6	-2.1	-0.2	0.7	0.5	0.4	-0.0	-0.8	-0.2
Shortness of breath walking on level ground	1.5	1.8	4.4	-1.6	-1.6	-0.8	-0.9	-2.1	-1.3	-0.3	0.2	-1.8
Qualifications: College or University degree	1.1	3.4	13.8	1.0	0.2	3.7	0.4	-0.3	1.4	3.0	1.7	1.6
Eye problems/disorders: None of the above	0.9	1.1	2.8	-0.8	-1.0	1.7	-1.2	-0.4	-1.1	-1.5	-0.4	-0.4
Mouth/teeth dental problems: Loose teeth	2.7	3.2	7.2	-1.8	-2.2	-1.1	-0.2	-0.8	-2.7	-1.9	-1.6	-2.2
Emphysema/chronic bronchitis	1.3	1.5	4.4	-0.9	1.8	-1.8	-0.3	0.3	-0.2	1.0	2.1	-0.5
Medication for pain relief, constipation, heartburn	0.3	0.4	2.5	0.0	-1.6	0.5	-1.0	0.2	0.1	-0.1	-0.2	-0.0
Neck or shoulder pain in last month	0.6	0.9	2.9	-1.6	0.8	0.2	-0.6	-0.2	-1.7	0.6	0.6	-0.7
Medication: Blood pressure	0.7	1.3	5.4	-0.8	-1.5	-0.6	-2.3	-1.1	-0.3	1.0	-0.7	-0.6
Angina (self-reported)	1.1	1.5	3.9	-0.9	1.4	0.5	2.0	0.6	-0.9	0.2	1.8	-1.4
Migraine (self-reported)	1.4	1.7	6.8	1.1	-0.5	1.3	-0.4	-2.6	0.6	-0.8	-1.9	0.7
Medication: Ibuprofen	0.5	0.6	1.7	1.0	0.4	0.1	0.0	0.1	0.8	1.0	-0.7	1.3
Medication: Allopurinol	0.5	0.7	2.8	0.0	-1.2	-0.3	-0.3	-1.7	-0.7	-0.4	-0.9	-0.3
Medication: Omeprazole	1.2	1.4	3.5	-1.9	0.7	0.3	0.4	-0.1	-1.3	-1.6	0.7	-1.8
Medication: Seretide 50 evohaler	0.6	0.7	2.9	0.2	-1.5	-1.7	-0.1	0.3	0.8	-0.4	-0.1	-0.3
Mean time to correctly identify matches	1.2	2.3	7.8	2.7	-0.0	-0.3	0.5	0.6	2.8	0.8	-0.9	1.8
Heart disease (mother)	0.2	0.3	1.0	0.9	0.1	1.0	0.3	-0.1	0.3	0.5	-0.0	-0.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.6	2.0	4.4	1.8	1.3	-1.0	0.7	1.5	2.1	1.5	0.2	1.4
Whole body fat mass	0.5	2.2	6.5	-2.5	0.7	-0.8	-0.4	-0.4	-2.0	-0.5	1.5	-2.3
Leg fat mass (right)	0.5	2.1	6.7	-2.6	0.6	-0.8	-0.2	-0.7	-2.1	-0.6	1.0	-2.2
Arm predicted mass (right)	0.4	2.2	4.7	-1.7	1.4	2.1	-0.3	-0.1	-2.2	0.7	2.2	-0.8
Pulse rate, automated reading	0.5	1.6	3.6	-1.1	0.7	1.3	0.6	0.8	-1.6	-0.8	1.8	-1.9
Alcohol intake frequency.	0.3	0.7	4.6	0.8	0.2	-0.3	-0.1	-2.1	0.7	-0.3	-0.4	0.8
Comparative height size at age 10	0.9	4.8	15.4	-1.0	2.4	3.3	-0.0	3.9	-1.4	1.8	2.1	-0.7
Number of full sisters	1.0	1.2	2.7	-1.1	-1.0	-1.6	-0.8	-1.0	-1.2	-1.2	-0.8	-0.5
Suffer from ‘nerves’	1.4	2.2	6.6	2.0	-2.6	0.8	0.4	-1.3	1.7	0.4	-1.2	1.4
Overall health rating	0.4	0.8	2.2	-0.9	0.2	-1.5	0.3	-0.2	-0.1	1.3	0.9	-1.3
Chest pain or discomfort	0.4	0.5	1.2	-1.0	0.2	1.1	-0.1	-0.3	-1.0	0.4	0.0	-1.0
Had major operations	1.0	1.2	6.2	-0.5	2.5	0.1	0.5	0.9	0.0	1.3	1.2	-0.5
Age at last live birth	1.4	2.0	5.5	-1.4	0.5	-1.0	2.0	1.1	-1.2	-2.3	-0.6	-1.6
Family relationship satisfaction	0.7	0.8	4.6	0.3	-0.7	-0.3	2.1	0.7	-0.4	-1.0	0.5	0.3
Leg pain on walking	1.4	1.7	3.5	-1.8	1.6	-1.7	-0.7	0.2	-1.9	-0.5	0.9	-1.3
Qualifications: NVQ or HND or HNC or equivalent	0.3	0.4	2.0	-1.4	-0.6	-0.4	-0.4	-0.2	-0.6	0.6	0.2	-0.6
Commuting to job workplace: Car/motor vehicle	1.4	1.7	7.5	1.1	0.8	2.7	1.5	1.4	0.9	-0.4	-0.4	-0.2
Illness, injury, bereavement, stress in last 2 years	0.9	1.1	3.8	0.6	0.2	-1.0	-1.1	-2.0	-0.2	-1.7	-0.2	-0.5
Medication: Aspirin	0.6	0.8	1.4	-0.9	1.2	0.1	0.9	-1.2	-0.5	-0.2	0.9	-1.2
Supplements: Vitamin C	2.4	2.9	6.3	2.5	-0.3	2.1	-1.4	-1.0	2.1	1.8	-0.6	1.9
Knee pain experienced in last month	0.6	1.0	2.1	-1.0	-0.8	0.2	-1.2	0.1	-1.5	-1.0	-1.3	-0.9
Hypertension (Self-reported)	0.3	0.7	3.2	-0.0	0.1	-1.1	-0.8	-1.8	-0.3	0.3	0.8	-0.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	2.2	2.6	7.9	-0.9	2.8	1.4	0.9	-0.6	0.0	2.4	2.4	-0.6
Illnesses of father: Heart disease	0.6	0.8	3.2	-1.1	0.2	0.9	0.3	-0.7	-1.8	-0.2	0.8	-1.0
Illnesses of siblings: Diabetes	1.1	1.4	3.7	-0.4	-0.5	-0.8	0.6	1.1	-1.4	-1.8	-1.0	-1.9
Smoking status: Previous	0.6	0.9	2.5	-1.1	0.7	0.3	-0.0	0.9	-1.2	-0.9	0.5	-1.6
Forced expiratory volume in 1-second (FEV1), predicted	0.6	1.2	3.6	-0.6	0.4	0.9	0.9	1.6	-1.4	-0.4	1.9	-0.5
Whole body fat-free mass	0.5	2.6	6.3	-1.3	1.9	2.5	0.2	0.4	-2.1	0.6	2.5	-0.7
Leg fat-free mass (right)	0.6	3.0	6.8	-2.0	1.9	2.1	0.4	0.6	-2.6	-0.1	2.4	-1.4
Arm fat percentage (left)	0.5	2.2	6.6	-2.6	0.9	-1.0	0.1	-0.3	-1.9	-0.5	1.1	-2.4
Average weekly red wine intake	0.5	0.8	2.2	-0.8	-0.2	-1.2	0.2	1.4	-0.5	0.3	1.5	-0.6
Handedness (chirality/laterality): Left-handed	0.4	0.5	1.6	0.6	-0.5	0.3	-1.0	-0.3	0.4	-0.7	-1.2	0.3
Mood swings	0.4	0.7	2.2	-0.7	-1.2	-0.1	-0.7	-1.0	-0.0	1.5	-0.7	0.4
Loneliness, isolation	0.9	1.3	4.1	0.1	-2.0	0.8	0.3	0.9	-1.1	-1.0	-1.2	-1.5
Long-standing illness, disability or infirmity	1.1	1.6	4.3	-1.6	-0.3	1.6	-0.2	-0.5	-2.1	-0.3	1.1	-1.9
Ever had bowel cancer screening	0.3	0.3	0.7	0.4	0.4	0.5	-0.8	0.6	0.8	0.4	-0.7	0.1
Diabetes diagnosed by doctor	1.5	2.5	6.6	-1.2	-0.5	-0.7	-1.1	-1.9	-2.3	-2.6	-0.6	-1.8
Ever had stillbirth, spontaneous miscarriage or termination	0.7	0.7	1.6	-0.1	0.2	1.3	-1.2	0.8	0.5	1.3	0.7	0.5
Friendships satisfaction	0.7	0.8	3.8	0.5	0.7	-0.7	1.9	0.5	-0.3	-0.4	1.2	-0.5
Qualifications: nursing, teaching	0.5	0.8	3.3	-0.3	0.8	1.1	0.3	0.8	-0.2	0.5	1.8	-0.9
Commuting to job workplace: Walk	0.9	1.0	4.0	-0.3	-0.8	-2.0	-0.2	0.1	-0.3	-1.7	-0.9	-0.6
Eye problems/disorders: Cataract	1.3	1.5	4.7	-0.5	0.1	-1.2	2.2	1.5	-1.3	-0.4	0.3	-1.7
Mouth/teeth dental problems: Mouth ulcers	0.7	1.0	3.7	-0.6	0.3	0.9	-0.8	-0.1	-1.0	1.9	1.7	0.1
Medication for cholesterol	1.4	2.2	12.8	-0.8	0.2	1.7	0.8	3.6	-0.5	0.9	-1.2	-0.5
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.7	0.9	2.5	0.5	-1.6	0.4	-0.8	-0.7	-0.8	-1.1	-1.3	-0.6
Back pain experienced in last month	1.1	1.6	6.0	1.0	-2.4	-0.6	0.0	-1.0	0.3	-0.9	-2.3	0.5
Mineral and other dietary supplements	1.6	2.1	5.9	1.8	0.4	-1.3	-0.3	-1.8	2.2	0.4	-0.4	2.4
Breast cancer (self-reported)	0.4	0.5	1.9	0.3	0.3	-1.4	-0.6	0.5	-0.2	-0.9	0.1	-0.7
Asthma (self-reported)	0.6	1.1	3.4	-1.0	-0.8	0.2	-1.8	-0.5	-1.4	-1.4	-0.3	-1.1
Osteoporosis (self-reported)	1.7	2.2	5.1	-0.8	1.7	-0.8	2.3	2.0	-0.7	1.2	2.0	-0.6
Osteoarthritis (self-reported)	1.9	2.5	5.3	-2.3	-0.5	1.3	-2.3	-2.3	-1.6	-0.3	-0.4	-1.2
Medication: Aspirin	0.5	0.7	1.8	-0.4	1.1	0.1	1.1	-1.3	-0.4	-0.1	0.8	-0.8
Medication: Gliclazide	0.6	0.7	2.2	0.9	-0.7	1.5	-0.7	-0.6	-0.0	0.9	-0.8	0.2
Illnesses of father: None of the above (group 1)	1.0	1.2	3.8	1.3	0.6	-0.4	-0.3	1.1	2.0	1.3	0.1	1.3
Smoking status: Current	1.8	2.8	8.0	-0.5	-1.4	-2.8	-1.6	-1.7	-0.4	-1.9	-2.4	0.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.1	2.3	4.5	1.4	1.5	-0.5	1.5	2.1	1.2	1.7	1.7	1.6
Whole body water mass	0.5	2.7	6.9	-1.4	2.0	2.6	0.2	0.4	-2.0	0.7	2.5	-0.7
Leg predicted mass (right)	0.5	2.9	6.8	-2.0	1.9	2.1	0.3	0.6	-2.6	-0.1	2.4	-1.3
Arm fat mass (left)	0.5	2.0	5.2	-2.3	1.4	-0.2	0.1	-0.5	-1.9	-0.5	1.6	-2.1
Number of self-reported non-cancer illnesses	0.8	1.4	4.0	-1.6	1.1	-0.1	0.2	-2.0	-1.0	-0.4	1.3	-1.6
Average weekly champagne plus white wine intake	3.1	4.2	11.5	-0.4	3.3	1.5	3.1	1.5	0.3	0.9	3.4	-1.0
Miserableness	0.4	0.7	2.4	0.4	-1.0	0.9	-0.9	-0.2	0.2	1.0	-1.6	0.5
Guilty feelings	0.2	0.3	1.4	-0.4	0.8	-0.3	1.2	0.5	-0.1	-0.5	0.1	-0.5
Wears glasses or contact lenses	0.5	0.6	2.0	0.6	-0.2	-1.4	0.8	1.2	0.5	0.7	0.5	-0.2
Ever taken oral contraceptive pill	1.1	1.2	2.8	1.5	-0.7	0.8	0.2	1.0	1.2	-0.6	-1.7	1.3
Hearing aid user	0.5	0.6	2.9	0.4	0.6	1.7	0.9	1.0	0.2	0.4	0.0	0.2
Mother’s age at death	1.4	1.7	5.0	2.2	-1.0	-0.4	1.3	0.6	1.7	-0.7	-1.8	0.9
Financial situation satisfaction	0.3	0.3	2.0	-0.3	-0.1	0.1	0.4	0.1	0.0	1.4	0.8	0.1
Tinnitus: Yes, now most or all of the time	1.3	1.5	6.3	1.2	0.3	2.5	-0.4	0.7	1.2	1.2	0.0	1.4
Commuting to job workplace: Public transport	0.6	0.7	3.3	-1.3	-0.3	-1.0	0.2	-1.8	-0.4	-0.1	0.6	-0.3
Eye problems/disorders: Glaucoma	2.0	2.4	6.4	2.3	0.2	-1.2	-0.9	-1.4	2.5	1.1	-0.3	2.0
Medication: Blood pressure	0.7	1.4	5.1	0.7	1.1	-1.4	1.1	-1.4	0.8	-0.0	2.3	-0.0
Pain type(s) experienced in last month: Hip pain	0.3	0.3	1.3	-0.2	0.8	-1.1	0.2	0.3	-0.1	0.2	0.7	-0.5
Supplements: Fish oil (including cod liver oil)	1.4	1.8	4.5	-1.4	-1.5	0.3	-1.6	0.6	-2.1	-1.0	-0.1	-1.9
High cholesterol (Self-reported)	0.2	0.4	0.9	-0.4	-0.7	-0.8	0.9	-0.9	-0.1	-0.4	0.2	-0.6
Medication: Bendroflumethiazide	0.4	0.6	2.6	-0.3	-1.1	0.0	-1.6	-0.9	0.2	0.8	0.2	-0.4
Medication: Paracetamol	0.5	0.7	2.6	-0.9	0.4	-0.8	-0.2	0.6	-1.6	-0.8	-0.2	-1.1
Medication: Lisinopril	0.3	0.4	1.7	0.5	-1.3	-0.1	-1.1	-0.7	0.3	0.2	-0.3	-0.4
Medication: Atorvastatin	0.5	0.6	3.6	-0.1	-0.2	-0.8	-0.5	-1.9	0.2	0.9	0.3	0.3
Illnesses of father: High blood pressure	0.6	0.7	1.4	0.9	-1.2	0.1	0.9	0.2	1.1	-0.2	-1.1	0.9
Alcohol drinker status: Never	0.2	0.2	0.8	-0.5	-0.3	0.9	-0.3	-0.6	-0.1	-0.5	-0.4	0.0
Ever smoked	1.1	1.9	4.1	-1.2	-0.7	-0.9	-1.0	0.3	-2.0	-2.0	-1.3	-1.8
Basal metabolic rate	0.4	2.4	5.6	-1.6	1.8	2.2	0.2	0.3	-2.1	0.5	2.4	-1.0
Leg fat percentage (left)	0.6	2.3	5.1	-2.3	-1.1	-1.7	-0.9	-1.5	-1.4	-1.1	-0.2	-2.3
Arm fat-free mass (left)	0.3	1.7	4.8	-1.1	1.1	2.2	-0.4	-0.7	-1.5	0.6	2.0	-0.8
Number of operations (self-reported)	0.9	1.4	5.4	-0.2	2.3	0.4	0.8	1.2	-0.3	1.0	1.9	-0.7
Average weekly beer plus cider intake	0.7	1.0	3.9	-0.4	-0.1	0.6	-2.0	-0.9	-0.1	-1.4	-1.4	0.5
Irritability	0.4	0.6	2.0	-0.8	0.5	-0.1	0.4	0.5	-0.4	1.4	1.4	-0.2
Risk taking	2.0	2.9	7.7	-2.1	-0.1	1.0	-2.8	-2.4	-2.0	-0.0	1.6	-0.9
Ever had prostate specific antigen (PSA) test	1.0	1.2	3.4	1.9	-0.5	-0.6	1.6	1.5	1.1	0.5	-0.4	0.1
Fractured/broken bones in last 5 years	0.5	0.6	2.6	-0.2	0.9	0.7	-1.6	0.3	-0.6	-0.5	1.0	-0.2
Age started oral contraceptive pill	2.1	2.6	9.2	-1.5	0.2	-1.6	0.4	-0.6	-1.8	-2.3	0.3	-3.0
Diastolic blood pressure, automated reading	1.4	4.2	9.9	-2.5	0.9	-2.8	1.0	0.8	-1.5	0.3	3.1	-3.1
Ever depressed for a whole week	1.0	1.2	2.9	1.5	-1.0	-1.5	1.7	-0.7	1.1	-0.8	-0.5	0.5
Unable to work because of sickness or disability	0.4	0.6	2.5	-1.0	1.2	-0.3	0.0	-0.3	-0.0	-0.1	1.6	-0.3
Commuting to job workplace: Cycle	1.1	1.3	4.0	0.2	0.4	0.5	1.5	1.9	0.7	2.0	0.3	1.1
Myopia	0.7	1.0	2.8	-1.0	0.2	-0.2	0.4	1.0	-1.1	-0.9	1.5	-1.7
Vascular/heart problems diagnosed by doctor	0.3	0.8	3.7	-0.1	-0.2	1.2	0.3	1.9	-0.1	-0.5	-1.1	0.7
Cholesterol lowering medication	1.3	2.0	4.8	-1.0	0.3	-2.2	0.7	-1.0	-1.6	-1.4	1.4	-2.0
Medication: Omeprazole (e.g. Zanprol)	3.0	3.7	9.0	-2.9	1.7	-0.9	1.3	0.3	-2.1	-1.5	1.9	-3.0
Pain experienced in last month	0.1	0.2	0.6	0.4	-0.1	-0.5	0.5	0.4	0.5	-0.8	0.5	-0.1
Supplements: Calcium	0.7	0.7	2.1	-0.9	-0.3	-0.8	0.5	-0.4	-0.8	-1.4	0.5	-1.4
Basal cell carcinoma (self-reported)	0.8	0.9	2.3	0.5	-0.9	1.5	-0.7	0.8	0.2	0.8	-1.2	1.3
Heart attack/myocardial infarction (self-reported)	0.7	0.9	2.8	-1.2	0.4	-0.6	-0.0	-0.8	-1.2	-1.1	-0.5	-1.7
Deep venous thrombosis (DVT) (self-reported)	1.4	1.8	4.3	-1.5	0.2	-1.2	-0.2	2.1	-1.9	0.1	1.5	-1.3
Heart disease (siblings)	0.8	1.0	2.8	-0.5	-0.4	-1.3	0.4	-0.9	-1.1	-1.7	0.6	-1.3
Alcohol drinker status: Previous	1.7	1.9	7.8	-0.8	0.7	-1.9	0.8	-0.9	-1.4	-2.8	0.2	-1.4
Pack years of smoking	0.7	1.0	2.7	-0.5	-0.2	-0.4	-1.6	-1.6	-0.7	-1.3	-0.7	-0.8
Impedance of whole body	0.3	1.5	5.3	0.5	-0.6	-1.6	-0.0	2.3	1.8	0.2	-1.1	0.6
Leg fat mass (left)	0.7	2.6	8.1	-2.8	0.2	-1.0	-0.5	-0.8	-2.4	-0.9	0.9	-2.5
Arm predicted mass (left)	0.3	1.6	4.3	-1.3	0.9	2.1	-0.5	-0.5	-1.8	0.5	1.7	-0.8