Hub : Genes

MUC12

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 TCGA Head and Neck Squamous Cell Carcinoma 0.0601 0.0338 0.0091 0.002 0.010 0.005 NA 0.002 0.160 0.0230 0.0830 NA 0.20
2 TCGA Kidney Renal Papillary Cell Carcinoma 0.0920 0.0500 0.0055 0.012 0.033 0.036 NA 0.006 0.067 0.0056 0.0039 NA 0.13

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2
Bipolar Disorder (2018) 0.9 1.5 2.7 0.5 1.6
Bipolar Disorder or Schizophrenia 2.4 5.8 11.6 -0.1 3.4
Depressed Affect (Nagel 2018) 0.1 0.2 0.4 0.3 -0.6
Depression (Nagel 2018) 0.6 0.9 1.8 -1.4 0.1
Intelligence (Savage-Jansen 2018) 0.1 0.3 0.5 -0.7 -0.3
Neuroticism (Nagel 2018) 0.3 0.7 1.3 -0.4 -1.1
Schizophrenia (2018) 2.0 4.2 8.3 -0.4 2.9
Schizophrenia vs Biploar Disorder 2.7 3.6 5.6 -1.3 2.4
Worry (Nagel 2018) 0.6 1.2 2.0 -1.4 -0.7
Alzheimer’s Disease (in mother) 0.7 0.8 1.6 0.3 1.3
Alzheimer’s Disease (in father) 0.4 0.5 0.9 -0.1 -1.0
Alzheimer’s Disease (including proxy) 0.1 0.2 0.4 0.2 0.6
Crohns Disease (2017) 0.8 1.7 3.4 -1.8 0.1
Irritable Bowel Disease (IBD) 0.9 2.2 3.9 -2.0 -0.8
Ulcerative Colitis (UC) 0.8 1.4 1.6 -1.1 -1.3
Major Depression (MDD) 0.8 1.0 1.5 -0.8 -1.2
Reaction Time 0.1 0.2 0.4 -0.6 -0.1
Verbal and Numeric Reasoning (VNR) 0.6 1.3 2.5 -1.6 0.4
Breast Cancer 0.0 0.0 0.0 -0.1 -0.1
Ovarian Cancer 2.3 3.1 6.1 -2.5 -0.1
Prostate Cancer 0.2 0.3 0.4 -0.3 -0.6
Age at First Birth 0.5 0.7 1.4 0.4 -1.2
Bipolar Disorder (2011) 0.0 0.0 0.0 0.0 0.0
Body Mass Index (BMI) (2010) 0.2 0.3 0.5 -0.7 0.3
Coronary Artery Disease (CAD) 1.7 2.0 3.9 0.3 2.0
Crohns Disease (2012) 1.6 2.6 3.4 -1.9 1.3
Mean Putamen Volume 0.2 0.3 0.4 -0.3 0.7
Fasting Glucose 1.0 1.1 2.3 1.5 -0.1
HbA1C 1.2 1.3 1.7 0.9 -1.3
HDL Cholesterol 0.6 0.9 1.9 1.4 0.1
LDL Cholesterol 0.2 0.4 0.7 0.1 0.8
Lupus 1.4 2.1 3.0 1.1 -1.7
Neuroticism (2016) 2.2 3.2 3.8 -2.0 -1.6
Primary Biliary Cirrhosis 0.0 0.0 0.1 0.0 -0.2
Rheumatoid Arthritis 1.3 1.8 3.5 -1.9 -0.4
Schizophrenia (2014) 3.3 7.4 13.7 -1.0 3.7
Triglycerides 0.4 0.6 1.3 -0.1 1.1
Type 2 Diabetes (T2D) (2012) 0.6 0.7 1.3 -0.1 1.2
Ulcerative Colitis 0.2 0.3 0.5 -0.2 -0.7
Blood Eosinophil Count 0.0 0.4 0.7 -0.2 0.9
Blood Platelet Count 0.5 5.8 10.0 -1.2 -3.2
Blood Red Count 0.3 2.8 4.8 -2.2 -0.9
Blood White Count 0.0 0.2 0.4 0.3 0.6
Heel T-Score 0.9 7.3 14.0 3.7 0.8
BMI 0.1 0.3 0.5 -0.4 0.7
Height 0.0 0.0 0.0 -0.0 0.2
Waist Hip Ratio (WHR) 0.4 1.8 3.2 0.7 -1.8
Systolic Blood Pressure 0.6 2.9 5.2 2.3 0.8
Smoking Status 0.4 0.9 1.3 -1.1 -0.7
Allergy or Eczema 0.2 0.5 0.7 0.5 -0.9
Cardiovascular Disease 0.2 0.6 1.2 -1.1 0.2
Hypothyroidism (self reported) 0.9 2.0 3.5 1.9 -0.7
Respiratory disease 0.3 0.6 1.2 0.0 -1.1
Type 2 Diabetes (T2D) (2018) 1.2 2.2 4.3 2.1 -0.2
Lung FEV1/FVC ratio 0.0 0.2 0.3 -0.1 0.6
Lung FVC 0.1 0.5 0.6 -0.8 -0.6
Neuroticism 0.3 0.7 1.3 -1.1 -0.4
Chronotype (morning person) 0.1 0.2 0.4 -0.7 0.2
Hair Pigment 0.3 7.2 10.7 1.9 -3.3
Tanning 0.0 0.4 0.6 0.4 0.7
Hand grip strength (left) 1.4 3.6 3.7 -1.9 1.9
Number of treatments/medications taken 0.3 0.6 1.1 1.1 0.2
Average weekly spirits intake 0.1 0.1 0.1 -0.4 -0.1
Sensitivity / hurt feelings 0.4 0.8 0.9 0.9 -0.8
Frequency of depressed mood in last 2 weeks 1.2 1.6 1.7 -1.3 -1.2
Hearing difficulty/problems: Yes 0.4 0.7 0.8 0.9 0.7
Relative age of first facial hair 0.1 0.2 0.3 0.6 0.0
Other serious medical condition/disability diagnosed by doctor 0.0 0.0 0.0 -0.1 0.0
Ever used hormone-replacement therapy (HRT) 0.8 1.1 2.1 0.1 -1.4
Ever had hysterectomy (womb removed) 0.3 0.3 0.6 0.8 -0.1
Systolic blood pressure, automated reading 1.1 3.1 5.0 2.2 1.1
Eye problems/disorders: Diabetes related eye disease 0.6 0.6 1.1 0.3 -1.1
Angina 1.2 1.6 2.3 1.5 -0.9
Medication for hormone replacement therapy 1.5 1.7 2.2 -1.5 -1.1
Vitamin and mineral supplements 0.2 0.3 0.5 -0.4 0.7
Supplements: Zinc 0.3 0.3 0.6 0.7 0.3
Medication: Co-codamol 0.5 0.6 1.2 -1.1 0.1
Medication: Metformin 0.5 0.7 1.4 -0.3 -1.2
Diabetes (father) 0.4 0.5 0.5 -0.7 -0.7
Diabetes (mother) 0.7 0.9 1.1 1.0 0.9
Severe depression (siblings) 0.0 0.1 0.1 0.3 -0.1
Pack years adult smoking proportion 1.3 1.9 2.8 1.7 1.1
Impedance of leg (right) 0.1 0.2 0.3 -0.5 -0.5
Leg fat-free mass (left) 0.0 0.1 0.1 -0.3 0.2
Trunk fat percentage 0.0 0.1 0.1 0.1 0.3
Hand grip strength (right) 1.3 3.6 5.3 -2.3 1.3
Townsend deprivation index at recruitment 0.5 0.7 1.4 -0.1 -1.2
Current tobacco smoking 1.3 2.2 4.3 -2.1 0.3
Average weekly fortified wine intake 1.1 1.3 2.5 0.1 1.6
Maternal smoking around birth 0.3 0.4 0.7 0.8 0.3
Fed-up feelings 0.3 0.6 0.8 0.6 -0.9
Frequency of unenthusiasm / disinterest in last 2 weeks 0.5 0.7 1.4 -1.2 -0.2
Relative age voice broke 0.0 0.0 0.1 -0.3 -0.1
Taking other prescription medications 0.7 1.2 1.7 0.8 -1.3
Age when periods started (menarche) 0.3 0.7 1.0 0.6 -1.0
Bilateral oophorectomy (both ovaries removed) 0.4 0.5 0.7 -0.5 0.8
Heel bone mineral density (BMD) T-score, automated (left) 0.2 0.4 0.8 0.9 0.1
Tinnitus: Yes, but not now, but have in the past 2.1 2.3 4.6 -2.1 0.1
Qualifications: CSEs or equivalent 0.1 0.1 0.2 -0.4 -0.2
Serious illness, injury or assault to yourself 1.6 1.9 3.5 0.5 -1.9
High blood pressure 0.0 0.0 0.0 0.1 0.2
Hayfever, allergic rhinitis or eczema 0.2 0.5 0.7 0.6 -0.8
Multivitamins +/- minerals 0.1 0.2 0.3 0.2 0.5
Stomach or abdominal pain in last month 2.4 3.0 5.1 2.3 -1.0
Supplements: Glucosamine 0.5 0.6 1.3 1.1 -0.1
Diverticular disease/diverticulitis (self-reported) 0.5 0.5 0.6 -0.8 0.7
Medication: Atenolol 0.5 0.6 1.1 0.4 -1.1
Medication: Levothyroxine sodium 2.9 5.0 5.4 2.3 -2.1
Sitting height 0.1 0.6 1.1 -1.1 -0.0
Chronic bronchitis/emphysema (father) 0.5 0.6 0.9 -0.9 0.6
High blood pressure (mother) 0.7 1.0 1.3 0.8 -1.2
Body mass index (BMI) 0.2 0.7 0.7 -0.8 0.9
Impedance of leg (left) 0.1 0.5 0.6 -0.8 -0.7
Leg predicted mass (left) 0.0 0.1 0.1 -0.3 0.2
Trunk fat mass 0.0 0.1 0.1 -0.3 0.3
Waist circumference 0.0 0.1 0.2 -0.4 0.4
Number of incorrect matches in round 0.1 0.2 0.4 -0.6 0.0
Past tobacco smoking 1.3 2.4 2.5 -1.6 1.5
Alcohol usually taken with meals 1.5 2.5 4.8 2.2 0.3
Nervous feelings 1.7 3.1 4.8 -1.2 -2.2
Frequency of tenseness / restlessness in last 2 weeks 1.6 2.4 2.5 -1.6 -1.5
Hearing difficulty/problems with background noise 1.5 2.3 4.3 -0.6 2.1
Hair/balding pattern: Pattern 2 0.7 0.8 1.2 -0.6 -1.1
Had menopause 0.2 0.2 0.4 0.6 0.3
Had other major operations 0.3 0.3 0.6 0.8 0.2
Forced vital capacity (FVC) 0.2 0.7 1.2 -1.1 -0.5
Heel bone mineral density (BMD) T-score, automated (right) 0.2 0.5 1.1 1.0 -0.0
Ever unenthusiastic/disinterested for a whole week 0.9 1.1 1.8 -1.4 -0.6
Qualifications: None of the above 0.4 0.9 1.7 0.4 1.3
Financial difficulties in last 2 years 0.9 1.3 1.9 0.8 -1.4
Mouth/teeth dental problems 0.7 1.1 1.5 -1.2 -0.8
Heart attack 0.2 0.2 0.4 0.7 -0.1
Allergy 0.3 0.6 0.8 -0.7 0.9
Pain all over the body in last month 0.4 0.4 0.9 -0.9 0.1
Diabetes (self-reported) 0.7 1.1 2.2 1.5 0.0
Hayfever/allergic rhinitis (self-reported) 1.3 1.8 3.5 1.9 -0.1
Medication: Ramipril 0.6 0.8 1.4 1.2 -0.4
Medication: Simvastatin 0.3 0.5 0.9 0.9 -0.3
Fluid intelligence score 1.2 2.5 5.1 -2.3 0.1
Illnesses of siblings 0.5 0.7 1.3 1.1 0.3
Neuroticism score 0.4 0.9 1.0 -1.0 -0.9
Weight 0.2 0.8 0.9 -1.0 0.8
Impedance of arm (right) 0.3 1.3 2.6 1.6 0.0
Arm fat percentage (right) 0.0 0.2 0.3 0.0 0.6
Trunk fat-free mass 0.2 1.0 1.6 -1.3 0.6
Hip circumference 0.6 2.6 3.6 -1.9 1.2
Time employed in main current job 2.2 2.6 4.3 -2.1 0.9
Alcohol intake versus 10 years previously 0.3 0.4 0.7 0.9 -0.3
Father’s age at death 0.2 0.2 0.3 -0.4 0.6
Worrier / anxious feelings 0.7 1.3 2.3 -1.5 -0.5
Frequency of tiredness / lethargy in last 2 weeks 0.6 1.1 1.6 -1.3 -0.7
Falls in the last year 0.3 0.5 0.9 0.3 -0.9
Hair/balding pattern: Pattern 3 0.3 0.4 0.7 0.9 0.4
Number of live births 1.3 1.9 3.7 1.9 -0.0
Forced expiratory volume in 1-second (FEV1) 0.1 0.3 0.4 -0.6 -0.5
Pulse rate 6.9 11.6 22.4 -4.7 0.9
Happiness 0.5 0.6 0.7 -0.8 0.8
Noisy workplace 0.2 0.3 0.6 -0.8 -0.0
Qualifications: A levels/AS levels or equivalent 0.5 1.2 1.3 -1.0 1.1
Serious illness, injury or assault of a close relative in last 2 years 1.1 1.2 2.4 1.5 0.2
Mouth/teeth dental problems: Dentures 1.0 1.6 1.8 1.2 1.3
Asthma 0.1 0.2 0.5 0.7 -0.1
Medication: Ibuprofen (e.g. Nurofen) 0.4 0.5 1.0 1.0 -0.1
Medication: Cholesterol lowering 0.5 0.8 1.6 1.3 0.1
Depression (self-reported) 1.4 1.7 3.5 1.9 0.1
Medication: Lansoprazole 0.2 0.3 0.3 0.6 0.5
Prospective memory result 0.1 0.1 0.2 0.3 0.4
Lung cancer (father) 0.4 0.5 0.8 -0.5 -0.9
Illnesses of mother 2.7 3.3 6.2 -2.5 -0.7
Forced expiratory volume in 1-second (FEV1), Best measure 0.1 0.3 0.5 -0.2 -0.7
Pulse wave Arterial Stiffness index 0.7 0.8 0.9 -1.0 -0.8
Impedance of arm (left) 0.3 1.5 2.3 1.5 -0.8
Arm fat mass (right) 0.0 0.2 0.3 -0.2 0.5
Trunk predicted mass 0.2 1.0 1.7 -1.3 0.6
Standing height 0.0 0.0 0.1 -0.3 0.0
Length of working week for main job 0.8 0.9 1.6 -0.5 -1.3
Exposure to tobacco smoke at home 0.6 0.7 1.1 1.0 -0.5
Breastfed as a baby 1.7 2.1 4.0 0.4 2.0
Tense / ‘highly strung’ 0.5 0.9 1.1 0.8 -1.1
Seen doctor (GP) for nerves, anxiety, tension or depression 0.8 1.2 2.5 1.6 0.0
Hair/balding pattern: Pattern 4 0.1 0.2 0.4 -0.0 0.6
Birth weight of first child 1.3 2.3 3.6 -1.9 -1.1
Peak expiratory flow (PEF) 0.3 0.8 1.1 0.7 -1.1
Pulse wave reflection index 0.5 0.6 1.1 0.0 -1.1
Ever highly irritable/argumentative for 2 days 0.8 1.0 1.8 -1.3 0.5
Loud music exposure frequency 0.1 0.1 0.1 0.3 0.2
Qualifications: O levels/GCSEs or equivalent 0.3 0.5 1.0 -1.0 -0.0
Mouth/teeth dental problems: Bleeding gums 2.7 3.5 6.8 2.6 0.4
Blood clot in the leg (DVT) 1.9 2.4 2.9 1.7 -1.4
Medication: Paracetamol 0.1 0.2 0.2 0.5 0.3
Headache pain in last month 0.2 0.4 0.7 0.8 -0.4
Medication for cholesterol, blood pressure or diabetes 0.3 0.6 1.0 -1.0 0.3
Glaucoma (self-reported) 0.3 0.3 0.4 0.6 0.5
Gout (self-reported) 0.3 0.4 0.6 -0.4 0.8
Hypothyroidism/myxoedema (self-reported) 3.5 6.8 9.1 3.0 -2.1
Medication: Amlodipine 0.4 0.6 0.9 0.5 -1.0
Medication: Ventolin 100micrograms inhaler 0.0 0.1 0.1 0.3 0.2
Birth weight 1.7 3.8 5.6 -2.4 1.4
Chronic bronchitis/emphysema (mother) 1.1 1.3 2.3 -1.5 0.5
High blood pressure (siblings) 0.1 0.1 0.2 -0.0 -0.5
Forced vital capacity (FVC), Best measure 0.2 0.7 0.9 -1.0 -0.7
Body fat percentage 0.1 0.2 0.3 -0.4 0.5
Leg fat percentage (right) 0.3 1.0 1.7 -1.3 0.6
Arm fat-free mass (right) 0.2 0.8 1.3 -1.2 0.5
Exposure to tobacco smoke outside home 0.6 0.9 1.5 0.5 -1.2
Comparative body size at age 10 0.8 2.3 3.6 1.9 1.0
Number of full brothers 1.2 1.5 2.5 1.6 -0.6
Worry too long after embarrassment 0.6 1.0 2.0 -1.4 -0.3
Seen a psychiatrist for nerves, anxiety, tension or depression 0.1 0.1 0.2 -0.5 0.3
Wheeze or whistling in the chest in last year 0.4 0.8 1.2 -1.1 0.6
Number of children fathered 0.7 0.8 1.1 0.8 -1.0
Reason for reducing amount of alcohol drunk: Health precaution 1.4 1.6 2.9 0.5 1.7
Age at first live birth 0.2 0.3 0.4 -0.6 -0.4
Pulse wave peak to peak time 0.8 0.9 1.0 0.9 1.0
Health satisfaction 0.0 0.0 0.0 0.1 0.2
Shortness of breath walking on level ground 0.5 0.6 0.7 -0.8 0.7
Qualifications: College or University degree 0.1 0.4 0.8 0.9 -0.2
Eye problems/disorders: None of the above 0.1 0.1 0.2 0.2 0.4
Mouth/teeth dental problems: Loose teeth 1.5 1.8 2.3 1.5 -1.1
Emphysema/chronic bronchitis 0.5 0.6 1.1 -1.0 -0.3
Medication for pain relief, constipation, heartburn 0.4 0.8 1.3 -1.1 -0.4
Neck or shoulder pain in last month 0.1 0.1 0.3 0.1 -0.5
Medication: Blood pressure 0.1 0.2 0.3 0.5 -0.2
Angina (self-reported) 0.8 1.0 1.3 1.2 -0.8
Migraine (self-reported) 0.1 0.1 0.2 -0.2 0.5
Medication: Ibuprofen 0.3 0.4 0.5 0.7 0.6
Medication: Allopurinol 0.1 0.1 0.2 -0.1 -0.4
Medication: Omeprazole 0.0 0.0 0.0 0.2 -0.0
Medication: Seretide 50 evohaler 1.7 1.9 2.3 1.3 -1.5
Mean time to correctly identify matches 0.2 0.3 0.4 0.7 0.5
Heart disease (mother) 0.2 0.3 0.6 -0.0 0.8
Reproduciblity of spirometry measurement using ERS/ATS criteria 1.9 2.3 2.8 1.3 -1.7
Whole body fat mass 0.0 0.2 0.2 -0.4 0.4
Leg fat mass (right) 0.1 0.6 0.8 -0.9 0.6
Arm predicted mass (right) 0.3 1.7 3.0 -1.7 0.7
Pulse rate, automated reading 10.0 32.2 62.7 -7.9 1.3
Alcohol intake frequency. 0.1 0.1 0.1 -0.3 -0.4
Comparative height size at age 10 0.1 0.4 0.8 -0.1 0.9
Number of full sisters 1.0 1.2 1.9 1.4 0.6
Suffer from ‘nerves’ 1.5 2.4 2.6 -1.6 -1.5
Overall health rating 0.7 1.4 2.8 -0.2 -1.7
Chest pain or discomfort 0.2 0.2 0.5 -0.1 0.7
Had major operations 0.7 0.8 0.9 -0.8 -1.0
Age at last live birth 0.0 0.0 0.0 -0.1 -0.1
Family relationship satisfaction 0.1 0.1 0.2 -0.3 0.4
Leg pain on walking 0.7 0.9 1.8 1.3 0.1
Qualifications: NVQ or HND or HNC or equivalent 0.2 0.2 0.2 -0.4 -0.5
Commuting to job workplace: Car/motor vehicle 0.9 1.0 2.0 0.0 1.4
Illness, injury, bereavement, stress in last 2 years 2.0 2.4 3.5 -1.9 1.2
Medication: Aspirin 1.6 2.1 3.7 1.9 -0.7
Supplements: Vitamin C 0.1 0.2 0.3 0.6 0.0
Knee pain experienced in last month 0.7 1.1 1.3 1.1 -1.0
Hypertension (Self-reported) 0.0 0.1 0.2 0.1 0.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.1 0.1 0.2 -0.4 -0.2
Illnesses of father: Heart disease 3.1 4.2 8.5 0.1 2.9
Illnesses of siblings: Diabetes 0.2 0.2 0.2 -0.4 -0.4
Smoking status: Previous 2.5 3.8 6.2 2.5 -1.2
Forced expiratory volume in 1-second (FEV1), predicted 0.4 0.8 1.6 -1.2 -0.3
Whole body fat-free mass 0.1 0.7 1.1 -1.0 0.5
Leg fat-free mass (right) 0.0 0.0 0.1 -0.3 0.0
Arm fat percentage (left) 0.0 0.0 0.0 -0.2 0.2
Average weekly red wine intake 0.2 0.3 0.5 -0.4 0.7
Handedness (chirality/laterality): Left-handed 1.5 1.8 2.7 -0.9 1.7
Mood swings 0.3 0.5 0.5 -0.7 -0.7
Loneliness, isolation 1.3 1.8 3.6 0.1 -1.9
Long-standing illness, disability or infirmity 1.2 1.8 3.4 1.9 -0.4
Ever had bowel cancer screening 0.6 0.7 1.2 1.1 -0.4
Diabetes diagnosed by doctor 2.0 3.2 6.5 2.5 -0.2
Ever had stillbirth, spontaneous miscarriage or termination 0.1 0.1 0.1 0.4 -0.1
Friendships satisfaction 0.1 0.1 0.1 0.0 -0.4
Qualifications: nursing, teaching 0.9 1.4 2.9 -0.1 -1.7
Commuting to job workplace: Walk 0.1 0.2 0.2 -0.3 -0.4
Eye problems/disorders: Cataract 0.3 0.4 0.5 -0.6 -0.7
Mouth/teeth dental problems: Mouth ulcers 0.1 0.2 0.4 -0.1 0.6
Medication for cholesterol 0.8 1.2 2.2 1.5 0.6
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.6 0.7 1.4 -1.2 0.0
Back pain experienced in last month 0.9 1.2 2.0 -1.4 0.7
Mineral and other dietary supplements 0.3 0.5 0.8 -0.4 0.9
Breast cancer (self-reported) 1.1 1.3 1.8 0.9 -1.3
Asthma (self-reported) 0.1 0.3 0.5 0.7 -0.2
Osteoporosis (self-reported) 1.6 2.0 3.7 -0.5 -1.9
Osteoarthritis (self-reported) 0.4 0.5 0.8 0.5 -0.9
Medication: Aspirin 1.6 2.1 3.4 1.9 -0.9
Medication: Gliclazide 0.4 0.5 0.8 -0.3 -0.9
Illnesses of father: None of the above (group 1) 0.8 1.0 1.4 0.7 -1.2
Smoking status: Current 2.0 3.1 6.3 -2.5 0.1
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.4 0.9 1.3 -1.1 -0.7
Whole body water mass 0.1 0.6 1.0 -1.0 0.4
Leg predicted mass (right) 0.0 0.0 0.0 -0.1 0.1
Arm fat mass (left) 0.0 0.2 0.2 -0.5 0.3
Number of self-reported non-cancer illnesses 1.4 2.4 4.5 2.1 -0.5
Average weekly champagne plus white wine intake 0.2 0.3 0.4 0.6 -0.4
Miserableness 0.2 0.3 0.6 -0.8 0.2
Guilty feelings 0.3 0.5 0.7 -0.8 0.5
Wears glasses or contact lenses 0.0 0.0 0.0 0.1 -0.1
Ever taken oral contraceptive pill 0.9 0.9 1.4 -1.2 -0.7
Hearing aid user 0.8 0.9 1.2 -1.1 -0.7
Mother’s age at death 1.2 1.5 3.0 1.7 0.3
Financial situation satisfaction 0.4 0.5 0.8 0.3 0.9
Tinnitus: Yes, now most or all of the time 1.2 1.5 2.9 0.1 1.7
Commuting to job workplace: Public transport 0.3 0.4 0.8 -0.2 0.9
Eye problems/disorders: Glaucoma 0.1 0.1 0.3 -0.5 -0.0
Medication: Blood pressure 0.6 1.1 1.6 -0.7 1.3
Pain type(s) experienced in last month: Hip pain 1.9 2.3 2.8 -1.7 1.4
Supplements: Fish oil (including cod liver oil) 0.6 0.7 1.4 1.2 -0.3
High cholesterol (Self-reported) 1.4 2.5 5.0 0.1 2.2
Medication: Bendroflumethiazide 0.0 0.1 0.1 0.4 0.1
Medication: Paracetamol 0.2 0.4 0.7 0.2 0.8
Medication: Lisinopril 0.8 1.0 1.9 1.4 0.2
Medication: Atorvastatin 1.4 1.8 2.0 -1.4 1.2
Illnesses of father: High blood pressure 0.9 1.1 2.2 -0.2 -1.5
Alcohol drinker status: Never 0.6 0.8 1.3 1.2 -0.5
Ever smoked 1.9 3.3 4.9 2.2 -1.3
Basal metabolic rate 0.1 0.5 0.9 -0.9 0.4
Leg fat percentage (left) 0.3 1.0 1.8 -1.3 0.4
Arm fat-free mass (left) 0.3 1.4 2.0 -1.4 0.8
Number of operations (self-reported) 0.2 0.3 0.5 0.3 -0.7
Average weekly beer plus cider intake 0.6 0.9 1.3 -1.1 -0.7
Irritability 1.9 3.3 3.4 1.9 -1.8
Risk taking 0.6 0.8 1.0 -0.8 -1.0
Ever had prostate specific antigen (PSA) test 0.1 0.1 0.1 0.3 -0.3
Fractured/broken bones in last 5 years 0.4 0.5 1.0 -1.0 -0.3
Age started oral contraceptive pill 0.3 0.3 0.7 -0.8 -0.1
Diastolic blood pressure, automated reading 1.9 6.0 7.3 -2.7 2.2
Ever depressed for a whole week 0.1 0.1 0.2 -0.5 -0.1
Unable to work because of sickness or disability 0.5 0.6 0.9 -0.6 -1.0
Commuting to job workplace: Cycle 0.3 0.4 0.4 0.5 -0.7
Myopia 2.4 3.5 5.8 2.4 -1.1
Vascular/heart problems diagnosed by doctor 0.0 0.1 0.1 0.3 -0.1
Cholesterol lowering medication 0.2 0.3 0.5 -0.7 0.3
Medication: Omeprazole (e.g. Zanprol) 0.0 0.0 0.0 0.0 0.0
Pain experienced in last month 0.3 0.5 0.9 0.9 0.1
Supplements: Calcium 0.1 0.1 0.1 0.3 -0.4
Basal cell carcinoma (self-reported) 1.1 1.3 2.5 -0.4 1.6
Heart attack/myocardial infarction (self-reported) 0.0 0.0 0.1 0.3 0.1
Deep venous thrombosis (DVT) (self-reported) 1.7 2.2 2.3 1.4 -1.5
Heart disease (siblings) 0.0 0.0 0.0 -0.2 0.1
Alcohol drinker status: Previous 0.7 0.8 1.5 -1.2 -0.4
Pack years of smoking 1.7 2.5 3.6 1.9 1.2
Impedance of whole body 0.0 0.2 0.3 0.4 -0.6
Leg fat mass (left) 0.1 0.5 0.7 -0.8 0.6
Arm predicted mass (left) 0.3 1.3 2.0 -1.4 0.8