TWAS hub - MYBPC1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.279	0.0460	3.3e-15	0.132	0.163	0.186	0.189	0.185	8.5e-16	2.1e-19	4.4e-22	1.8e-22	5.0e-22
2	GTEx	Nerve Tibial	0.238	0.0762	1.5e-04	0.018	NA	-0.004	NA	0.022	1.7e-02	NA	7.9e-01	NA	1.1e-02

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Chronic bronchitis/emphysema (mother)	6.0	7.0	8.8	2.3	-3.0
Supplements: Vitamin C	3.9	4.6	6.3	1.7	2.5
Medication: Atorvastatin	3.9	4.9	6.7	-1.8	-2.6
Alcohol intake versus 10 years previously	3.7	5.5	7.8	1.8	2.8
Frequency of unenthusiasm / disinterest in last 2 weeks	3.6	4.7	5.3	-2.0	2.3
Prospective memory result	2.9	3.6	7.1	2.7	-0.3
Comparative height size at age 10	2.8	15.3	26.3	-2.1	-5.1
Rheumatoid Arthritis	2.7	3.7	4.0	1.9	-2.0
Qualifications: NVQ or HND or HNC or equivalent	2.7	3.2	6.2	0.5	2.5
Ovarian Cancer	2.6	3.4	6.5	-0.6	-2.5
Financial situation satisfaction	2.6	3.2	5.1	2.2	1.1
Eye problems/disorders: Diabetes related eye disease	2.3	2.6	4.5	-0.8	2.1
Stomach or abdominal pain in last month	2.3	2.9	4.7	1.0	2.2
Happiness	2.3	2.8	5.2	0.7	2.3
Medication: Ventolin 100micrograms inhaler	2.2	2.8	3.6	1.9	1.4
Neck or shoulder pain in last month	2.2	3.1	4.4	1.3	-2.1
Medication: Blood pressure	2.2	3.9	7.9	0.1	-2.8
Ever had stillbirth, spontaneous miscarriage or termination	2.2	2.4	4.5	2.1	0.4
High blood pressure (mother)	2.1	3.0	4.7	-1.1	-2.2
Mouth/teeth dental problems: Bleeding gums	2.1	2.7	5.4	2.3	0.1
Glaucoma (self-reported)	2.1	2.4	2.9	-1.4	1.7
Exposure to tobacco smoke outside home	2.1	2.8	3.2	1.6	1.8
Medication: Aspirin	2.1	2.7	4.6	-0.9	-2.2
Supplements: Calcium	2.1	2.3	3.2	1.8	1.2
Hair/balding pattern: Pattern 3	2.0	2.9	5.4	2.3	0.7
Qualifications: nursing, teaching	2.0	3.1	4.2	-2.0	1.4
Forced vital capacity (FVC), Best measure	1.9	7.0	12.7	-1.1	-3.6
Illnesses of father: High blood pressure	1.9	2.4	4.0	-2.0	-0.8
Number of full sisters	1.8	2.2	4.2	0.4	2.0
Breast cancer (self-reported)	1.8	2.1	3.4	-0.9	-1.8
Illnesses of father: Heart disease	1.7	2.3	3.6	1.9	1.1
Hearing difficulty/problems: Yes	1.6	2.4	3.6	-1.1	1.9
Medication: Levothyroxine sodium	1.6	2.7	5.2	0.4	2.3
Forced vital capacity (FVC)	1.6	6.3	11.1	-1.2	-3.3
Mouth/teeth dental problems: Mouth ulcers	1.6	2.5	4.7	0.5	-2.2
Age started oral contraceptive pill	1.6	2.0	3.0	-1.7	-1.0
Reaction Time	1.5	2.8	4.0	2.0	1.3
Other serious medical condition/disability diagnosed by doctor	1.5	1.9	2.8	-1.0	1.7
Tinnitus: Yes, but not now, but have in the past	1.5	1.6	3.2	0.2	-1.8
Qualifications: None of the above	1.5	3.2	4.9	1.2	-2.2
Financial difficulties in last 2 years	1.5	2.0	4.0	2.0	-0.3
Allergy	1.5	3.4	5.9	-0.9	-2.4
Noisy workplace	1.5	1.8	3.1	-0.8	-1.8
Pain type(s) experienced in last month: Hip pain	1.5	1.9	2.5	1.6	-1.1
Average weekly beer plus cider intake	1.5	2.1	4.2	-0.2	2.1
Schizophrenia vs Biploar Disorder	1.4	1.9	3.2	-1.8	-0.8
Alzheimer’s Disease (in mother)	1.4	1.7	2.0	1.4	1.2
Alzheimer’s Disease (in father)	1.4	1.5	2.2	-1.5	0.9
Coronary Artery Disease (CAD)	1.4	1.7	3.2	-1.8	-0.5
Length of working week for main job	1.4	1.6	2.2	1.0	1.5
Medication: Aspirin	1.4	1.8	3.1	-0.7	-1.8
Sensitivity / hurt feelings	1.3	2.2	3.8	0.8	-1.9
Forced expiratory volume in 1-second (FEV1), predicted	1.3	2.8	4.6	1.0	-2.1
Smoking status: Current	1.3	2.0	2.4	-1.2	-1.6
Schizophrenia (2018)	1.2	2.4	4.0	-2.0	-0.9
Bipolar Disorder (2011)	1.2	1.2	2.2	0.3	1.5
Height	1.2	22.9	45.8	-0.2	-6.8
Vitamin and mineral supplements	1.2	1.6	2.4	-1.6	-0.9
Alcohol drinker status: Previous	1.2	1.4	2.7	-0.4	-1.6
LDL Cholesterol	1.1	1.8	2.0	-1.4	1.3
Qualifications: CSEs or equivalent	1.1	1.4	2.7	1.7	-0.3
Asthma	1.1	2.1	4.0	0.4	2.0
Medication: Lansoprazole	1.1	1.3	2.2	1.5	0.6
Chest pain or discomfort	1.1	1.6	2.5	0.9	1.6
Asthma (self-reported)	1.1	2.1	4.1	0.4	2.0
Ever taken oral contraceptive pill	1.1	1.2	2.4	-0.3	1.5
Commuting to job workplace: Public transport	1.1	1.3	2.4	-1.6	-0.3
Relative age of first facial hair	1.0	2.0	2.2	1.5	1.3
Diabetes (self-reported)	1.0	1.5	2.3	0.9	1.5
Standing height	1.0	9.9	19.0	-0.9	-4.4
Qualifications: O levels/GCSEs or equivalent	1.0	1.6	2.0	-1.4	-1.1
Medication for cholesterol, blood pressure or diabetes	1.0	1.6	3.2	0.3	1.8
Mouth/teeth dental problems: Loose teeth	1.0	1.2	2.3	0.4	1.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.0	1.1	1.8	-1.4	0.6
Commuting to job workplace: Walk	1.0	1.1	1.8	-0.7	-1.3
Type 2 Diabetes (T2D) (2018)	0.9	1.7	2.5	0.9	1.6
Number of treatments/medications taken	0.9	1.5	2.9	-0.4	-1.7
Medication for hormone replacement therapy	0.9	1.0	1.9	-1.4	0.2
Severe depression (siblings)	0.9	1.0	1.7	0.6	-1.3
Hand grip strength (right)	0.9	2.6	5.1	-2.3	-0.0
Current tobacco smoking	0.9	1.5	2.2	-0.8	-1.5
Hayfever, allergic rhinitis or eczema	0.9	2.1	3.7	0.6	1.9
Mouth/teeth dental problems	0.9	1.3	1.8	-0.9	1.4
Depression (self-reported)	0.9	1.1	2.1	-1.5	0.2
Forced expiratory volume in 1-second (FEV1), Best measure	0.9	3.0	5.8	-0.4	-2.4
Tense / ‘highly strung’	0.9	1.4	2.5	0.6	-1.6
Peak expiratory flow (PEF)	0.9	2.1	3.5	-0.8	-1.9
Mean time to correctly identify matches	0.9	1.8	2.4	1.5	1.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.9	1.1	1.7	-0.8	1.3
Average weekly red wine intake	0.9	1.4	2.8	-0.2	-1.7
Friendships satisfaction	0.9	1.1	1.3	1.1	-0.9
Medication for cholesterol	0.9	1.4	2.4	1.5	0.6
Alzheimer’s Disease (including proxy)	0.8	1.2	2.4	0.1	1.6
Lupus	0.8	1.2	2.2	0.5	1.5
Smoking Status	0.8	1.9	3.7	0.2	-1.9
Lung FEV1/FVC ratio	0.8	4.3	6.5	1.4	2.5
Ever used hormone-replacement therapy (HRT)	0.8	1.0	1.9	-1.4	0.3
Ever had hysterectomy (womb removed)	0.8	0.9	1.7	1.3	-0.2
Number of full brothers	0.8	1.0	1.9	0.1	-1.4
Overall health rating	0.8	1.6	3.3	-0.1	1.8
Hypertension (Self-reported)	0.8	2.2	2.3	1.4	-1.5
Medication: Gliclazide	0.8	0.9	1.6	0.3	1.3
Commuting to job workplace: Cycle	0.8	0.9	1.2	-0.8	1.1
Intelligence (Savage-Jansen 2018)	0.7	2.1	4.1	-2.0	0.3
Age at First Birth	0.7	1.0	1.2	0.9	1.1
Schizophrenia (2014)	0.7	1.6	1.8	-1.3	-1.2
Systolic blood pressure, automated reading	0.7	1.9	3.7	1.9	0.4
Medication: Metformin	0.7	1.0	1.1	1.0	1.1
Townsend deprivation index at recruitment	0.7	1.0	1.9	-1.4	-0.4
Average weekly fortified wine intake	0.7	0.8	1.6	-0.1	1.3
Taking other prescription medications	0.7	1.1	2.1	-1.4	0.4
High blood pressure	0.7	2.0	2.9	1.0	-1.7
Medication: Atenolol	0.7	0.9	1.7	0.2	-1.3
Past tobacco smoking	0.7	1.2	2.4	-0.2	1.6
Hair/balding pattern: Pattern 2	0.7	0.9	1.3	-1.1	-0.7
Fluid intelligence score	0.7	1.4	1.9	-1.0	1.4
Birth weight	0.7	1.4	2.9	-0.1	-1.7
Smoking status: Previous	0.7	1.1	1.6	1.3	-0.7
Hearing aid user	0.7	0.8	1.6	-1.2	0.2
Mother’s age at death	0.7	0.9	1.8	-0.2	-1.3
Eye problems/disorders: Glaucoma	0.7	0.9	1.5	-0.6	1.2
Basal cell carcinoma (self-reported)	0.7	0.8	1.5	-1.2	-0.3
Bipolar Disorder or Schizophrenia	0.6	1.5	3.0	-1.7	0.2
Worry (Nagel 2018)	0.6	1.2	1.3	1.0	-1.1
Crohns Disease (2012)	0.6	1.0	1.3	1.2	0.8
Mean Putamen Volume	0.6	0.6	0.8	0.7	0.9
Neuroticism	0.6	1.4	2.6	0.4	-1.6
Chronotype (morning person)	0.6	1.4	1.9	1.4	0.9
Diabetes (father)	0.6	0.7	1.2	-1.1	0.4
Multivitamins +/- minerals	0.6	0.7	1.2	1.1	-0.5
Forced expiratory volume in 1-second (FEV1)	0.6	1.9	3.8	-0.1	-2.0
Number of children fathered	0.6	0.7	0.9	-0.7	-0.9
Eye problems/disorders: None of the above	0.6	0.7	1.3	1.1	-0.3
Emphysema/chronic bronchitis	0.6	0.7	0.9	-1.0	-0.6
Family relationship satisfaction	0.6	0.7	1.4	0.1	1.2
Leg pain on walking	0.6	0.7	1.4	0.1	1.2
Loneliness, isolation	0.6	0.8	1.6	-0.1	1.3
Tinnitus: Yes, now most or all of the time	0.6	0.7	1.2	-0.5	1.1
Medication: Bendroflumethiazide	0.6	0.9	1.7	-0.3	-1.3
Ever smoked	0.6	1.0	2.0	-0.2	-1.4
Pain experienced in last month	0.6	0.9	1.8	-1.3	-0.3
Heart attack/myocardial infarction (self-reported)	0.6	0.8	1.4	-1.2	0.3
Bipolar Disorder (2018)	0.5	0.9	1.6	-0.3	1.3
Fasting Glucose	0.5	0.6	1.1	1.1	0.3
Ulcerative Colitis	0.5	0.8	1.1	1.1	0.6
Hand grip strength (left)	0.5	1.2	2.3	-1.5	-0.3
Average weekly spirits intake	0.5	0.6	1.1	-0.1	-1.0
Supplements: Zinc	0.5	0.5	0.9	-0.2	1.0
Medication: Co-codamol	0.5	0.6	1.1	-0.2	-1.0
Bilateral oophorectomy (both ovaries removed)	0.5	0.6	1.2	-0.1	-1.1
Heel bone mineral density (BMD) T-score, automated (left)	0.5	1.1	1.7	0.7	1.3
Serious illness, injury or assault to yourself	0.5	0.6	0.8	-0.6	0.9
Supplements: Glucosamine	0.5	0.7	0.9	0.7	0.9
Chronic bronchitis/emphysema (father)	0.5	0.5	0.9	1.0	0.4
Had other major operations	0.5	0.6	0.7	0.7	-0.8
Heel bone mineral density (BMD) T-score, automated (right)	0.5	1.2	1.7	0.9	1.3
Ever unenthusiastic/disinterested for a whole week	0.5	0.6	0.8	-0.6	0.9
Medication: Simvastatin	0.5	0.7	1.2	-1.1	0.4
Pulse rate	0.5	0.8	1.5	-0.1	1.2
Medication: Ibuprofen (e.g. Nurofen)	0.5	0.7	1.3	0.2	-1.2
Medication: Cholesterol lowering	0.5	0.8	1.2	-0.6	-1.1
Hypothyroidism/myxoedema (self-reported)	0.5	1.0	1.7	0.5	1.3
Age at first live birth	0.5	0.9	1.5	-0.6	1.2
Medication: Ibuprofen	0.5	0.6	1.1	-0.0	-1.1
Medication: Allopurinol	0.5	0.7	1.2	-0.4	-1.1
Had major operations	0.5	0.6	1.1	-0.3	1.1
Illness, injury, bereavement, stress in last 2 years	0.5	0.6	0.8	-0.9	0.6
Handedness (chirality/laterality): Left-handed	0.5	0.6	1.2	1.1	-0.3
Osteoarthritis (self-reported)	0.5	0.7	1.1	-1.0	0.5
Illnesses of father: None of the above (group 1)	0.5	0.7	1.2	0.4	-1.1
Ever had prostate specific antigen (PSA) test	0.5	0.6	0.7	0.8	-0.7
Myopia	0.5	0.8	1.2	1.1	-0.6
Depression (Nagel 2018)	0.4	0.5	1.1	-1.0	0.1
Triglycerides	0.4	0.7	1.3	-1.1	-0.1
Systolic Blood Pressure	0.4	2.2	2.4	1.5	-1.4
Age when periods started (menarche)	0.4	0.9	1.8	-0.1	1.4
Diverticular disease/diverticulitis (self-reported)	0.4	0.4	0.5	0.6	0.7
Sitting height	0.4	2.5	4.7	-0.5	-2.2
Heart attack	0.4	0.6	1.0	-1.0	0.4
Neuroticism score	0.4	0.9	1.4	1.2	-0.6
Serious illness, injury or assault of a close relative in last 2 years	0.4	0.5	0.7	-0.8	-0.6
Mouth/teeth dental problems: Dentures	0.4	0.7	1.1	-0.5	-1.0
Birth weight of first child	0.4	0.7	1.2	0.5	-1.1
Medication: Paracetamol	0.4	0.6	1.2	-1.1	-0.2
Health satisfaction	0.4	0.5	0.9	-0.3	0.9
Shortness of breath walking on level ground	0.4	0.5	0.7	-0.6	0.8
Alcohol intake frequency.	0.4	1.0	1.2	0.9	1.1
Commuting to job workplace: Car/motor vehicle	0.4	0.4	0.8	0.3	0.9
Ever had bowel cancer screening	0.4	0.5	0.8	-0.9	0.5
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.4	0.4	0.5	-0.7	0.6
Osteoporosis (self-reported)	0.4	0.5	0.5	0.6	0.7
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.4	0.8	0.9	-0.8	-0.9
Miserableness	0.4	0.7	1.3	1.1	0.3
Unable to work because of sickness or disability	0.4	0.5	0.7	0.8	-0.6
Vascular/heart problems diagnosed by doctor	0.4	1.0	1.4	-0.8	1.2
Cholesterol lowering medication	0.4	0.6	1.0	-1.0	-0.4
Major Depression (MDD)	0.3	0.4	0.5	0.7	0.4
Verbal and Numeric Reasoning (VNR)	0.3	0.8	1.5	-1.2	0.0
Primary Biliary Cirrhosis	0.3	0.4	0.7	-0.8	-0.4
Type 2 Diabetes (T2D) (2012)	0.3	0.3	0.6	-0.8	-0.0
Blood Platelet Count	0.3	3.7	4.6	2.1	-1.7
Lung FVC	0.3	1.4	2.2	-0.9	-1.5
Frequency of depressed mood in last 2 weeks	0.3	0.4	0.4	-0.7	0.5
Diabetes (mother)	0.3	0.4	0.6	-0.4	0.8
Had menopause	0.3	0.4	0.8	-0.9	-0.2
Impedance of arm (right)	0.3	1.4	1.7	1.3	-1.0
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.4	0.7	-0.8	0.4
Blood clot in the leg (DVT)	0.3	0.4	0.7	0.8	0.3
Qualifications: College or University degree	0.3	1.0	1.2	-0.9	1.1
Heart disease (mother)	0.3	0.4	0.5	-0.7	0.6
Illnesses of siblings: Diabetes	0.3	0.3	0.6	-0.3	0.8
Diabetes diagnosed by doctor	0.3	0.5	0.6	0.7	0.8
Back pain experienced in last month	0.3	0.5	1.0	0.2	1.0
Alcohol drinker status: Never	0.3	0.4	0.7	-0.1	-0.8
Deep venous thrombosis (DVT) (self-reported)	0.3	0.4	0.6	0.8	0.4
Neuroticism (Nagel 2018)	0.2	0.5	1.0	-0.2	-1.0
Crohns Disease (2017)	0.2	0.4	0.7	0.8	0.3
HDL Cholesterol	0.2	0.3	0.4	0.7	-0.3
Blood White Count	0.2	1.4	2.0	0.9	-1.4
Waist Hip Ratio (WHR)	0.2	1.0	1.9	0.3	-1.4
Allergy or Eczema	0.2	0.4	0.5	0.7	0.6
Cardiovascular Disease	0.2	0.6	0.9	0.6	-1.0
Pack years adult smoking proportion	0.2	0.4	0.7	0.8	0.2
Trunk fat percentage	0.2	1.0	1.2	1.1	-0.8
Relative age voice broke	0.2	0.3	0.5	0.7	0.4
Trunk fat mass	0.2	0.9	1.5	0.6	-1.2
Waist circumference	0.2	0.6	1.3	-0.1	-1.1
Alcohol usually taken with meals	0.2	0.4	0.7	-0.2	-0.9
Nervous feelings	0.2	0.4	0.6	0.5	0.8
Hearing difficulty/problems with background noise	0.2	0.4	0.7	-0.2	0.9
Medication: Ramipril	0.2	0.3	0.4	0.7	-0.3
Weight	0.2	0.9	1.7	-0.4	-1.3
Trunk fat-free mass	0.2	1.3	1.3	-1.1	-1.1
Hip circumference	0.2	0.7	1.2	0.3	-1.1
Father’s age at death	0.2	0.3	0.6	0.2	-0.8
Worrier / anxious feelings	0.2	0.3	0.7	-0.1	-0.8
Frequency of tiredness / lethargy in last 2 weeks	0.2	0.2	0.3	0.5	0.5
Falls in the last year	0.2	0.3	0.6	-0.3	-0.8
Number of live births	0.2	0.2	0.4	0.2	-0.6
Impedance of arm (left)	0.2	1.0	1.0	1.0	-1.0
Trunk predicted mass	0.2	1.2	1.3	-1.1	-1.1
Arm fat-free mass (right)	0.2	1.0	1.4	-1.2	-0.7
Comparative body size at age 10	0.2	0.7	1.0	-1.0	-0.6
Seen a psychiatrist for nerves, anxiety, tension or depression	0.2	0.3	0.5	-0.3	-0.7
Medication for pain relief, constipation, heartburn	0.2	0.4	0.8	-0.1	0.9
Angina (self-reported)	0.2	0.3	0.3	0.5	-0.6
Medication: Omeprazole	0.2	0.3	0.6	-0.2	0.7
Pulse rate, automated reading	0.2	0.6	1.3	0.0	1.1
Age at last live birth	0.2	0.3	0.6	0.8	-0.1
Whole body fat-free mass	0.2	1.0	1.2	-0.9	-1.1
Whole body water mass	0.2	0.9	1.1	-0.8	-1.0
Supplements: Fish oil (including cod liver oil)	0.2	0.3	0.5	-0.7	0.2
Medication: Paracetamol	0.2	0.4	0.7	-0.8	-0.3
Basal metabolic rate	0.2	0.9	1.3	-0.7	-1.1
Arm fat-free mass (left)	0.2	1.2	1.5	-1.0	-1.2
Diastolic blood pressure, automated reading	0.2	0.7	1.4	1.2	-0.1
Ever depressed for a whole week	0.2	0.2	0.2	-0.5	0.4
Heart disease (siblings)	0.2	0.2	0.3	-0.4	-0.5
Impedance of whole body	0.2	0.9	1.1	0.9	-1.1
Arm predicted mass (left)	0.2	0.8	0.8	-0.9	-0.9
Depressed Affect (Nagel 2018)	0.1	0.1	0.1	-0.4	-0.4
Irritable Bowel Disease (IBD)	0.1	0.3	0.4	0.5	-0.6
HbA1C	0.1	0.1	0.1	0.0	0.3
Heel T-Score	0.1	0.9	1.1	1.1	0.9
Hypothyroidism (self reported)	0.1	0.2	0.2	0.4	0.5
Hair Pigment	0.1	1.9	2.2	1.5	-1.3
Tanning	0.1	1.4	2.0	-0.9	-1.4
Angina	0.1	0.1	0.2	0.2	-0.5
Impedance of leg (right)	0.1	0.4	0.8	0.0	-0.9
Leg fat-free mass (left)	0.1	0.5	0.9	-0.4	-1.0
Maternal smoking around birth	0.1	0.2	0.3	-0.5	0.2
Body mass index (BMI)	0.1	0.3	0.6	-0.1	0.8
Impedance of leg (left)	0.1	0.5	0.9	-0.1	-1.0
Leg predicted mass (left)	0.1	0.5	0.9	-0.4	-1.0
Number of incorrect matches in round	0.1	0.1	0.1	0.4	-0.4
Pain all over the body in last month	0.1	0.1	0.2	0.5	-0.1
Hayfever/allergic rhinitis (self-reported)	0.1	0.1	0.2	0.2	0.4
Arm fat percentage (right)	0.1	0.6	0.9	1.0	0.4
Time employed in main current job	0.1	0.2	0.2	0.4	0.4
Qualifications: A levels/AS levels or equivalent	0.1	0.1	0.3	0.0	-0.5
Lung cancer (father)	0.1	0.1	0.1	0.4	0.1
Illnesses of mother	0.1	0.1	0.1	0.4	0.2
Pulse wave Arterial Stiffness index	0.1	0.1	0.2	-0.2	-0.5
Exposure to tobacco smoke at home	0.1	0.1	0.1	0.4	0.3
Hair/balding pattern: Pattern 4	0.1	0.2	0.2	0.4	0.5
Loud music exposure frequency	0.1	0.1	0.2	-0.4	0.3
Gout (self-reported)	0.1	0.2	0.3	-0.6	0.2
Body fat percentage	0.1	0.6	0.9	1.0	-0.5
Wheeze or whistling in the chest in last year	0.1	0.1	0.2	-0.4	0.0
Reason for reducing amount of alcohol drunk: Health precaution	0.1	0.1	0.2	0.4	0.1
Medication: Seretide 50 evohaler	0.1	0.2	0.3	-0.6	0.0
Arm predicted mass (right)	0.1	0.8	0.9	-0.9	-0.8
Leg fat-free mass (right)	0.1	0.7	1.1	-0.5	-1.1
Arm fat percentage (left)	0.1	0.3	0.5	0.7	0.4
Long-standing illness, disability or infirmity	0.1	0.2	0.3	-0.5	0.3
Mineral and other dietary supplements	0.1	0.1	0.2	-0.2	-0.4
Leg predicted mass (right)	0.1	0.7	1.2	-0.5	-1.1
Wears glasses or contact lenses	0.1	0.1	0.2	-0.2	0.4
Medication: Lisinopril	0.1	0.2	0.3	0.1	-0.6
Number of operations (self-reported)	0.1	0.2	0.3	-0.2	0.5
Irritability	0.1	0.2	0.3	-0.2	-0.6
Risk taking	0.1	0.1	0.2	0.1	0.4
Pack years of smoking	0.1	0.1	0.2	0.4	-0.3
Ulcerative Colitis (UC)	0.0	0.0	0.1	0.1	-0.3
Breast Cancer	0.0	0.0	0.0	0.0	0.0
Prostate Cancer	0.0	0.0	0.0	0.0	0.0
Body Mass Index (BMI) (2010)	0.0	0.0	0.1	0.1	-0.2
Neuroticism (2016)	0.0	0.0	0.1	-0.3	-0.0
Blood Eosinophil Count	0.0	0.2	0.4	-0.3	-0.6
Blood Red Count	0.0	0.5	0.7	-0.5	0.8
BMI	0.0	0.2	0.2	-0.4	0.5
Respiratory disease	0.0	0.1	0.2	-0.1	0.4
Fed-up feelings	0.0	0.1	0.1	0.3	0.3
Frequency of tenseness / restlessness in last 2 weeks	0.0	0.1	0.1	-0.3	-0.2
Illnesses of siblings	0.0	0.1	0.1	-0.4	-0.0
Arm fat mass (right)	0.0	0.1	0.1	0.3	0.2
Breastfed as a baby	0.0	0.0	0.1	0.1	-0.2
Pulse wave reflection index	0.0	0.0	0.1	-0.3	0.1
Ever highly irritable/argumentative for 2 days	0.0	0.1	0.1	0.3	0.2
Headache pain in last month	0.0	0.0	0.0	-0.0	-0.0
Medication: Amlodipine	0.0	0.0	0.0	0.0	-0.0
High blood pressure (siblings)	0.0	0.0	0.0	-0.1	0.0
Leg fat percentage (right)	0.0	0.0	0.1	0.3	0.1
Worry too long after embarrassment	0.0	0.1	0.1	0.3	0.2
Pulse wave peak to peak time	0.0	0.0	0.0	-0.1	0.1
Migraine (self-reported)	0.0	0.0	0.0	-0.0	0.2
Whole body fat mass	0.0	0.2	0.3	0.3	-0.5
Leg fat mass (right)	0.0	0.0	0.0	0.1	-0.0
Suffer from ‘nerves’	0.0	0.0	0.1	0.2	0.2
Knee pain experienced in last month	0.0	0.0	0.0	0.0	-0.2
Mood swings	0.0	0.1	0.1	-0.4	-0.1
Eye problems/disorders: Cataract	0.0	0.0	0.0	0.2	-0.0
Arm fat mass (left)	0.0	0.0	0.0	0.1	0.0
Number of self-reported non-cancer illnesses	0.0	0.1	0.1	0.1	0.4
Average weekly champagne plus white wine intake	0.0	0.0	0.0	0.1	0.2
Guilty feelings	0.0	0.0	0.0	0.1	-0.0
Medication: Blood pressure	0.0	0.0	0.0	-0.2	0.2
High cholesterol (Self-reported)	0.0	0.1	0.1	-0.3	-0.3
Leg fat percentage (left)	0.0	0.0	0.0	0.2	0.0
Fractured/broken bones in last 5 years	0.0	0.0	0.0	0.0	-0.0
Medication: Omeprazole (e.g. Zanprol)	0.0	0.0	0.0	0.1	-0.1
Leg fat mass (left)	0.0	0.0	0.0	-0.0	-0.2

Hub : Genes

MYBPC1

Models

Trait associations