Hub : Genes

NCEH1

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0940	0.0320	1.2e-03	0.020	0.026	0.012	0.024	0.019	1.5e-03	3.8e-04	1.1e-02	0.00053	1.9e-03
2	GTEx	Artery Coronary	0.2240	0.0930	9.3e-03	-0.001	NA	-0.009	NA	-0.007	3.5e-01	NA	9.5e-01	NA	7.0e-01
3	GTEx	Artery Tibial	0.1205	0.0328	3.0e-06	0.054	NA	0.094	NA	0.088	4.4e-05	NA	8.2e-08	NA	2.2e-07
4	GTEx	Esophagus Muscularis	0.1410	0.0490	1.0e-03	0.056	NA	0.077	NA	0.060	2.5e-04	NA	2.1e-05	NA	1.5e-04
5	GTEx	Muscle Skeletal	0.2099	0.0441	4.6e-11	0.138	NA	0.158	NA	0.165	1.9e-13	NA	2.7e-15	NA	5.9e-16
6	GTEx	Pancreas	0.2000	0.0700	3.8e-03	-0.001	NA	-0.007	NA	-0.005	3.7e-01	NA	9.2e-01	NA	6.0e-01
7	GTEx	Skin Sun Exposed Lower leg	0.0900	0.0300	2.1e-04	0.098	NA	0.080	NA	0.094	1.7e-08	NA	3.5e-07	NA	3.6e-08
8	GTEx	Thyroid	0.1020	0.0400	2.1e-03	0.055	NA	0.036	NA	0.045	4.9e-05	NA	8.2e-04	NA	2.3e-04
9	TCGA	Breast Invasive Carcinoma	0.0389	0.0149	1.4e-04	-0.001	0.016	0.010	NA	0.003	4.5e-01	2.8e-04	3.7e-03	NA	6.5e-02
10	TCGA	Head and Neck Squamous Cell Carcinoma	0.0812	0.0322	7.0e-05	0.055	0.042	0.040	NA	0.059	7.9e-07	1.6e-05	2.5e-05	NA	3.1e-07
11	TCGA	Kidney Renal Clear Cell Carcinoma	0.0494	0.0189	3.9e-05	0.035	0.039	0.034	NA	0.035	7.1e-05	2.8e-05	9.1e-05	NA	7.5e-05
12	TCGA	Lung Adenocarcinoma	0.0292	0.0158	9.5e-03	0.019	0.015	0.005	NA	0.007	2.2e-03	6.2e-03	8.0e-02	NA	4.9e-02
13	TCGA	Lung Squamous Cell Carcinoma	0.0753	0.0279	9.3e-05	0.016	0.036	0.015	NA	0.017	5.6e-03	4.8e-05	6.3e-03	NA	4.1e-03
14	TCGA	Ovarian Serous Cystadenocarcinoma	0.1150	0.0530	4.6e-03	0.021	0.015	0.020	NA	-0.003	1.4e-02	3.3e-02	1.5e-02	NA	5.8e-01
15	TCGA	Pancreatic Adenocarcinoma	0.1180	0.0550	7.2e-03	0.065	0.037	0.038	NA	0.012	1.0e-03	1.1e-02	1.0e-02	NA	9.9e-02
16	TCGA	Skin Cutaneous Melanoma	0.5470	0.1580	9.6e-03	-0.010	0.007	-0.005	NA	-0.007	7.9e-01	2.1e-01	4.7e-01	NA	5.5e-01
17	TCGA	Thyroid Carcinoma	0.0390	0.0180	3.8e-03	0.046	0.020	0.012	NA	0.027	2.6e-05	3.9e-03	2.0e-02	NA	1.0e-03

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17
Bipolar Disorder (2018)	2.7	4.3	8.4	-2.6	0.9	2.4	1.6	2.7	1.1	2.2	2.7	2.0	1.8	2.9	2.0	0.9	0.4	2.8	1.8	2.4
Bipolar Disorder or Schizophrenia	3.0	7.3	15.2	-3.3	1.1	3.3	2.3	3.6	0.4	2.9	3.9	2.8	1.7	3.5	2.4	-0.3	1.0	2.5	2.7	3.9
Depressed Affect (Nagel 2018)	0.6	1.2	4.0	-0.6	0.1	1.3	1.6	1.6	-0.4	0.8	1.6	0.7	-0.3	0.8	1.0	-0.5	1.3	-0.2	2.0	1.5
Depression (Nagel 2018)	0.4	0.7	2.2	-0.2	0.8	0.9	0.9	0.7	0.7	1.0	1.1	-0.1	0.6	0.7	1.5	1.0	0.5	0.0	0.6	1.0
Intelligence (Savage-Jansen 2018)	0.1	0.5	2.5	1.2	1.1	0.2	0.1	0.4	0.1	0.3	0.4	-0.7	0.0	0.2	-0.6	-0.9	1.6	-0.6	0.0	0.2
Neuroticism (Nagel 2018)	1.1	2.6	5.1	-1.5	1.1	2.0	2.3	2.1	1.3	1.7	2.1	1.4	1.0	1.4	1.9	0.6	1.8	0.3	1.8	1.9
Schizophrenia (2018)	1.7	3.6	9.5	-2.3	0.7	2.3	1.7	2.5	-0.2	1.9	2.8	1.7	0.7	2.2	1.6	-1.3	0.9	1.1	2.4	3.1
Schizophrenia vs Biploar Disorder	0.3	0.4	1.3	0.2	-0.7	0.2	1.1	0.5	-1.0	0.0	0.7	0.6	-0.5	-0.1	0.0	-0.8	0.0	-0.9	0.1	0.7
Worry (Nagel 2018)	1.4	2.9	7.2	-1.3	1.8	1.6	2.7	1.8	1.2	1.5	1.8	1.2	1.1	1.6	2.2	1.5	2.4	1.0	1.5	1.6
Alzheimer’s Disease (in mother)	0.5	0.5	2.4	-0.9	0.0	0.2	0.2	0.2	1.2	-0.3	0.8	-0.5	-0.6	0.2	0.1	-1.4	1.5	0.1	0.6	0.7
Alzheimer’s Disease (in father)	0.6	0.7	4.3	-0.7	-0.3	-0.1	-0.3	-0.1	1.3	-0.4	0.4	0.7	0.2	0.3	0.3	-2.1	-0.3	-1.2	1.6	0.7
Alzheimer’s Disease (including proxy)	0.7	1.0	4.2	-1.2	-0.2	0.3	-0.3	0.2	1.8	0.1	0.7	-0.3	-0.0	0.3	0.2	-2.0	1.8	-0.6	1.6	0.8
Crohns Disease (2017)	0.4	0.9	2.7	-0.5	1.0	1.1	1.6	0.9	0.6	0.7	1.1	1.3	-1.2	0.8	1.1	0.0	-0.3	1.0	0.8	1.1
Irritable Bowel Disease (IBD)	0.4	0.9	5.2	-0.3	-0.2	0.9	1.1	0.7	-0.2	0.5	0.9	1.4	-0.8	0.7	1.0	1.3	-0.4	2.3	0.7	0.7
Ulcerative Colitis (UC)	0.7	1.3	9.3	0.1	-1.0	0.7	0.7	0.5	-0.6	0.3	0.6	1.5	-0.1	0.7	0.8	2.3	-0.5	3.1	0.2	0.3
Major Depression (MDD)	0.3	0.3	1.5	0.3	0.1	0.0	-1.1	-0.3	-1.2	-0.2	-0.1	0.6	1.2	-0.1	-0.3	-0.1	-0.1	0.4	0.4	-0.2
Reaction Time	0.4	0.8	5.3	-1.2	1.2	-0.4	0.4	-0.8	0.3	-0.1	-0.4	-0.5	-0.1	-0.1	0.9	2.3	1.5	1.1	0.2	-0.5
Verbal and Numeric Reasoning (VNR)	0.3	0.6	6.8	0.1	1.0	-0.3	-0.0	-0.1	0.8	-0.3	0.1	-0.8	0.2	0.0	-0.6	-0.7	2.6	-0.9	0.1	-0.1
Breast Cancer	1.6	3.9	10.0	1.9	0.6	-2.3	-2.8	-3.0	-0.1	-1.2	-3.2	-1.7	1.4	-2.1	-1.4	1.0	1.9	-0.5	-1.6	-3.1
Ovarian Cancer	0.7	0.9	1.9	1.4	-0.3	-1.1	-0.9	-1.1	-0.0	-1.1	-1.2	-0.7	-1.0	-1.3	-0.8	-0.2	1.0	-0.6	-0.9	-1.0
Prostate Cancer	0.9	1.3	7.5	0.2	-1.1	-0.3	-1.0	-0.6	-0.0	-0.6	-0.7	0.0	-0.9	-1.1	-2.0	-0.6	-2.7	-0.6	-1.9	-0.6
Age at First Birth	0.4	0.6	2.9	0.5	-0.7	0.0	-0.8	0.1	0.4	0.2	-0.0	-1.6	0.2	-0.3	-1.1	-0.7	-1.7	-1.0	-0.9	0.0
Bipolar Disorder (2011)	0.4	0.4	2.5	-1.5	1.6	-0.1	0.7	0.0	-0.3	-0.1	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.2	0.0
Body Mass Index (BMI) (2010)	1.9	2.7	5.9	1.6	1.1	-2.4	-0.7	-2.0	-1.4	-2.4	-1.4	-2.4	-1.3	-2.1	-1.7	-1.2	0.6	-1.5	-0.7	-1.4
Coronary Artery Disease (CAD)	0.9	1.1	3.0	-0.3	-0.8	-1.1	-0.8	-1.0	-1.0	-1.2	-1.0	-0.1	-1.3	-1.1	-1.7	-0.5	-1.3	0.5	-1.5	-0.9
Crohns Disease (2012)	0.2	0.4	1.9	0.5	0.2	0.1	0.3	-0.1	-0.7	-0.2	-0.1	0.9	-1.4	-0.5	0.2	-0.1	-0.9	1.3	0.5	-0.1
Mean Putamen Volume	0.3	0.3	1.1	1.0	0.1	0.1	0.2	-0.2	0.0	0.3	-0.3	0.7	-0.3	0.2	1.1	-0.2	1.0	-0.1	0.9	-0.1
Fasting Glucose	0.3	0.4	1.8	0.1	0.8	-0.2	0.3	-0.3	0.5	0.0	-0.9	0.2	0.7	-0.3	0.2	1.1	0.7	1.4	0.1	-1.0
HbA1C	1.1	1.3	6.4	1.3	-0.5	-0.1	-0.9	-0.3	1.1	0.5	-0.6	0.1	1.6	-0.0	0.4	2.5	1.7	1.5	-1.0	-1.2
HDL Cholesterol	0.2	0.4	2.6	0.8	0.5	0.4	0.5	-0.2	-1.6	0.7	-0.0	-0.1	0.1	0.1	0.6	1.2	-0.1	-0.8	-0.1	0.1
LDL Cholesterol	0.5	0.7	2.5	0.1	-0.3	-0.4	-1.4	-0.5	0.3	-0.3	-1.2	-1.1	-0.9	-0.9	-1.3	-0.3	0.2	-0.5	-1.6	-0.9
Lupus	0.7	1.1	3.3	-1.5	1.2	0.8	1.2	0.6	1.8	1.0	0.9	0.4	0.9	1.2	1.4	0.8	0.6	-0.3	0.9	1.3
Neuroticism (2016)	3.8	5.5	11.7	-1.5	0.9	3.2	2.1	3.1	-0.2	3.0	3.4	2.2	1.3	3.2	2.9	0.8	2.2	1.5	2.0	3.0
Primary Biliary Cirrhosis	1.2	1.8	7.5	-2.3	0.3	0.6	1.3	0.6	0.6	0.3	1.7	1.3	0.3	1.2	1.4	-1.1	1.4	-0.0	2.7	1.8
Rheumatoid Arthritis	0.3	0.4	1.5	0.8	-1.2	-0.2	-0.8	-0.0	0.5	-0.4	-0.2	-0.2	-0.0	-0.2	0.3	0.3	1.2	1.1	0.7	-0.0
Schizophrenia (2014)	2.0	4.4	9.9	-2.2	-0.9	2.4	1.7	2.8	-0.7	2.0	3.0	2.3	1.3	2.5	2.0	-0.3	0.3	2.1	2.5	3.1
Triglycerides	0.5	0.8	2.9	-1.7	-0.1	0.5	0.5	0.9	1.6	0.1	1.0	0.9	-1.2	0.9	0.3	-0.8	0.7	0.7	0.2	1.2
Type 2 Diabetes (T2D) (2012)	0.5	0.6	3.5	0.8	-0.8	-0.4	-0.3	-0.4	0.8	-0.4	-0.4	-0.9	-0.1	-0.6	-1.4	0.3	-0.9	-0.2	-1.9	-0.6
Ulcerative Colitis	0.7	1.0	8.5	-0.4	-1.2	0.7	-0.1	0.7	-0.2	0.6	0.2	0.8	0.5	0.6	0.6	1.8	-0.4	2.9	-0.6	0.0
Blood Eosinophil Count	0.1	0.9	3.9	2.0	0.4	-0.4	1.7	-0.0	-1.6	-0.6	0.5	1.4	-1.1	0.1	-1.1	-0.2	0.6	0.1	-0.4	0.4
Blood Platelet Count	0.3	3.0	15.7	0.4	-4.0	-1.7	-1.8	-1.7	-1.5	-1.9	-0.9	0.5	-1.8	-1.2	-1.0	-0.8	1.4	2.8	1.5	-1.3
Blood Red Count	0.3	3.1	6.5	2.0	0.4	-2.2	-0.9	-2.2	-1.1	-1.8	-2.0	-1.1	-1.8	-1.9	-2.1	-1.5	-1.3	-2.5	-1.7	-1.7
Blood White Count	0.1	1.1	6.8	2.6	-0.6	-0.9	0.9	-1.1	-2.1	-0.8	-0.3	-0.4	-0.4	-0.6	-0.4	1.2	-0.2	0.9	-0.6	-0.3
Heel T-Score	0.1	0.4	1.9	0.9	1.4	0.5	0.9	-0.1	-0.3	0.8	-0.2	0.4	0.1	0.5	0.9	1.1	-0.0	-0.1	-0.0	0.0
BMI	1.3	7.8	19.2	3.6	0.3	-3.4	-2.1	-3.2	-1.1	-3.2	-2.7	-2.3	-1.6	-3.4	-4.4	-1.2	-2.8	-2.5	-3.5	-2.8
Height	0.7	12.9	71.4	-5.2	5.5	1.5	2.2	2.6	8.4	0.2	3.4	4.4	-0.5	2.7	2.2	-2.9	0.5	2.2	3.1	3.0
Waist Hip Ratio (WHR)	0.4	1.9	6.5	-0.3	-1.2	-1.2	1.3	-1.0	1.3	-2.1	0.1	1.6	-2.4	-0.3	-0.1	-1.2	1.3	1.7	2.5	-0.0
Systolic Blood Pressure	0.5	2.6	6.0	0.1	1.1	-2.1	-1.4	-2.0	-0.4	-1.7	-2.3	-2.3	-1.0	-2.2	-2.0	0.1	1.9	-0.3	-0.7	-2.4
Smoking Status	0.7	1.8	12.8	-1.4	0.6	-1.7	-0.0	-1.3	0.2	-2.3	-0.5	-0.5	-3.6	-0.7	-0.9	-0.6	1.1	-0.1	-1.2	-0.4
Allergy or Eczema	1.4	3.6	8.2	-1.4	0.7	2.0	2.9	2.8	1.6	1.4	2.3	2.8	0.1	2.3	1.5	-0.8	0.7	1.8	2.1	2.1
Cardiovascular Disease	0.2	0.5	3.4	0.4	0.7	-0.5	0.4	-0.8	-1.8	-0.6	-0.2	-0.6	-0.7	-0.5	-0.6	0.0	-0.8	-0.7	-0.9	0.0
Hypothyroidism (self reported)	0.4	0.9	4.6	-0.4	1.5	1.3	0.4	1.2	-0.3	1.1	0.8	-0.0	0.1	0.8	-0.3	-2.1	0.0	-0.6	1.1	0.9
Respiratory disease	0.4	0.9	3.3	-1.6	0.7	-0.7	0.2	-0.7	1.8	-1.1	-0.2	-0.5	-0.7	-0.7	-0.7	-1.8	0.0	-1.3	0.4	0.0
Type 2 Diabetes (T2D) (2018)	0.7	1.3	2.6	0.1	1.6	-1.5	-0.5	-1.4	0.2	-1.5	-1.4	-0.6	-0.3	-1.2	-1.5	-1.0	1.6	-0.4	0.7	-1.3
Lung FEV1/FVC ratio	0.1	0.4	1.8	-0.0	-0.0	0.3	-0.7	0.3	-1.3	0.4	-0.1	0.7	0.7	0.2	0.1	0.6	-1.3	0.1	-0.9	0.2
Lung FVC	0.1	0.7	3.0	0.1	-1.7	0.0	-0.4	0.4	-1.1	-0.0	-0.5	0.7	0.7	0.2	1.3	1.0	0.3	1.5	0.9	-0.5
Neuroticism	1.5	3.7	10.8	-1.2	1.0	2.3	3.3	2.6	1.1	2.1	2.6	1.4	0.9	1.8	2.3	1.0	1.6	1.1	1.7	2.4
Chronotype (morning person)	0.7	1.5	8.1	-2.2	2.9	-1.1	-0.6	-1.1	-1.1	-0.8	-1.4	-0.7	-0.8	-0.4	-0.0	-0.1	1.3	1.0	0.2	-1.4
Hair Pigment	0.0	0.3	1.4	-0.6	-0.2	-0.2	-0.3	-0.2	-0.4	-0.2	-0.4	-0.9	-0.3	-0.4	-0.5	-0.1	-0.5	-0.6	-1.2	0.0
Tanning	0.1	1.2	5.4	-0.4	1.8	-0.9	0.8	-0.6	-2.3	-0.9	-0.6	-1.2	-1.8	-1.1	0.5	-0.2	0.1	0.5	1.6	-0.1
Hand grip strength (left)	0.4	1.1	10.5	-0.3	3.2	0.5	0.4	0.4	1.6	0.5	0.1	0.5	0.6	0.3	-0.1	-0.6	-1.7	0.5	0.2	0.4
Number of treatments/medications taken	1.6	2.9	6.2	-2.5	1.8	1.7	2.1	1.8	-0.5	1.7	1.8	2.5	0.8	2.1	1.5	-0.7	0.9	-0.3	2.4	1.7
Average weekly spirits intake	0.7	0.8	2.6	1.6	-0.7	1.5	0.9	1.2	-1.4	1.2	1.2	0.2	-0.1	0.5	0.1	-0.2	-0.7	0.2	1.0	0.5
Sensitivity / hurt feelings	0.3	0.6	1.7	-0.3	0.8	0.8	0.9	0.8	0.6	0.8	0.6	0.8	0.2	0.3	1.2	-0.0	1.3	0.2	0.7	0.6
Frequency of depressed mood in last 2 weeks	1.5	2.1	4.5	-1.1	1.1	1.9	1.9	2.1	1.5	1.9	1.9	0.5	0.5	1.6	1.7	0.5	1.1	0.7	1.1	1.6
Hearing difficulty/problems: Yes	0.6	0.8	2.5	1.4	-1.3	-0.1	-0.6	0.1	0.6	0.2	-0.8	-0.7	0.0	-0.8	-1.2	-0.2	-1.2	-1.3	-1.6	-1.0
Relative age of first facial hair	0.3	0.5	3.0	-0.4	-1.1	0.5	0.5	0.7	1.2	0.3	0.8	-0.1	0.4	0.6	0.7	-0.2	1.7	-0.2	0.5	0.7
Other serious medical condition/disability diagnosed by doctor	0.5	0.6	2.2	-0.9	-0.2	0.2	1.1	0.9	-1.4	0.2	-0.1	-0.1	-0.2	0.3	0.4	-1.5	-0.2	-0.7	1.5	0.1
Ever used hormone-replacement therapy (HRT)	1.6	2.0	7.3	-1.5	-0.6	1.1	1.7	1.4	-0.6	1.0	1.5	2.7	-0.4	1.7	2.0	-0.1	0.6	1.5	1.2	1.7
Ever had hysterectomy (womb removed)	0.6	0.7	2.0	1.0	-1.4	-0.9	-1.3	-0.9	-0.4	-0.8	-0.8	0.4	-0.3	-0.7	-0.3	-1.0	0.4	-1.1	0.1	-0.7
Systolic blood pressure, automated reading	1.6	4.7	11.4	1.4	0.9	-3.1	-2.0	-3.1	-1.0	-2.7	-3.3	-2.0	-1.5	-2.7	-2.5	0.2	0.8	-0.2	-1.7	-3.4
Eye problems/disorders: Diabetes related eye disease	0.7	0.8	5.0	-0.1	2.2	0.0	0.5	-0.4	1.1	0.2	-0.6	-0.5	-0.9	-0.3	0.1	-1.0	0.3	-1.6	1.2	-0.3
Angina	0.6	0.8	4.6	0.7	0.7	-0.3	-0.0	-0.2	-1.2	-0.3	-0.6	-0.1	-0.6	-0.8	-0.8	-2.1	-1.6	-0.6	0.7	-0.6
Medication for hormone replacement therapy	1.2	1.3	7.5	1.2	-2.1	-0.4	-1.1	-0.5	-0.6	-0.1	-1.0	-0.3	0.8	-0.7	-0.9	1.0	-2.7	0.1	-1.4	-1.1
Vitamin and mineral supplements	0.4	0.5	4.7	-0.8	0.9	-0.8	-0.1	-0.6	2.2	-0.5	-0.2	-0.5	0.5	-0.3	-0.3	0.5	0.4	-0.1	-0.8	-0.5
Supplements: Zinc	0.6	0.6	3.1	0.1	0.0	0.7	0.9	0.3	-0.2	1.0	0.2	1.3	0.1	0.6	1.8	1.5	-0.9	0.4	0.0	0.5
Medication: Co-codamol	0.4	0.4	1.6	0.3	-1.3	0.6	0.2	1.1	-0.2	0.6	0.4	-0.0	0.5	0.1	0.8	-0.8	0.4	-1.1	0.4	0.4
Medication: Metformin	0.8	1.2	3.5	1.2	-0.4	-1.2	-1.4	-1.6	-0.8	-0.9	-1.9	-0.3	-0.9	-1.3	-1.2	-0.9	0.1	-0.4	-0.3	-1.6
Diabetes (father)	1.3	1.6	4.4	0.1	-0.2	-1.5	-0.5	-1.9	-0.4	-1.5	-1.7	0.9	-1.3	-1.3	-0.0	2.1	0.3	1.7	-1.2	-1.5
Diabetes (mother)	1.9	2.4	4.9	0.3	-1.1	-2.2	-2.2	-2.0	-0.9	-2.0	-2.1	-1.5	-1.2	-1.7	-1.1	0.8	-0.3	0.6	-2.0	-1.8
Severe depression (siblings)	3.2	3.6	10.8	-2.1	-0.0	2.8	1.6	3.3	1.7	2.5	2.3	1.3	0.6	2.0	1.6	-1.5	-1.0	-0.1	1.5	2.5
Pack years adult smoking proportion	0.8	1.1	3.5	0.5	-0.2	1.2	1.9	1.6	0.6	0.9	1.8	0.4	-0.2	1.2	0.5	-0.1	1.1	-0.2	0.5	1.9
Impedance of leg (right)	0.4	2.0	5.6	-0.6	-1.7	1.3	-0.1	0.5	-0.7	1.8	0.5	0.5	1.4	1.1	2.4	2.2	1.9	1.6	2.0	0.3
Leg fat-free mass (left)	0.5	2.6	10.9	-0.3	3.3	-0.6	0.2	0.2	3.0	-1.3	0.6	0.6	-0.6	-0.3	-1.8	-2.9	-2.6	-0.9	-1.1	0.5
Trunk fat percentage	0.4	1.7	4.6	1.8	0.8	-1.3	-0.3	-1.1	-0.6	-1.6	-0.7	-0.5	-1.2	-1.3	-2.2	-0.8	-2.1	-1.1	-2.0	-0.8
Hand grip strength (right)	0.6	1.6	6.6	-0.3	2.6	1.3	1.0	1.4	1.6	1.2	1.0	1.6	-0.3	1.1	0.8	-1.4	-0.6	0.7	1.6	1.2
Townsend deprivation index at recruitment	2.8	3.9	8.7	-1.9	-0.0	2.5	2.4	2.8	1.6	2.1	2.9	2.9	-0.1	2.3	1.9	0.3	0.5	1.6	0.6	2.6
Current tobacco smoking	0.7	1.2	5.2	1.1	-0.1	-1.1	-0.4	-1.1	-0.5	-1.2	-0.5	-0.4	-1.6	-0.8	-1.9	0.4	-0.8	-0.6	-2.3	-0.8
Average weekly fortified wine intake	0.2	0.3	2.0	-0.1	-0.1	0.4	0.4	0.4	0.8	0.5	0.4	0.4	1.4	0.4	-0.1	0.7	-0.4	-0.4	-0.2	0.1
Maternal smoking around birth	1.0	1.4	5.2	-0.4	-1.9	0.4	1.5	0.8	0.3	-0.2	1.1	2.3	-0.6	0.8	0.8	-1.3	0.9	-0.4	2.3	1.1
Fed-up feelings	1.2	2.2	7.4	0.6	0.9	1.5	2.2	1.9	-0.3	1.2	1.9	0.9	0.8	1.0	1.1	-0.1	2.7	-0.6	2.3	1.6
Frequency of unenthusiasm / disinterest in last 2 weeks	0.9	1.3	3.8	-0.2	0.7	1.2	1.2	1.1	0.2	1.1	1.3	0.4	0.5	0.9	1.9	1.2	1.4	1.1	1.5	1.3
Relative age voice broke	0.7	1.1	3.7	-0.5	-1.2	0.3	0.8	0.5	1.1	0.5	0.4	1.6	0.6	0.8	1.8	0.5	1.9	0.6	1.7	0.5
Taking other prescription medications	0.5	0.8	2.4	-0.9	1.0	1.1	0.8	0.9	-0.1	1.3	0.7	1.5	0.9	1.0	0.5	-0.8	-0.5	-0.6	0.7	0.6
Age when periods started (menarche)	0.6	1.4	4.6	-1.8	-0.3	1.6	0.8	1.0	-0.2	2.1	0.6	1.4	1.0	1.6	1.4	1.1	1.2	0.5	0.5	0.6
Bilateral oophorectomy (both ovaries removed)	0.5	0.6	2.7	0.4	-0.2	-0.4	1.2	0.3	-1.0	-0.7	0.6	0.6	-1.6	-0.1	-0.6	-0.7	-0.5	-0.2	-1.1	0.6
Heel bone mineral density (BMD) T-score, automated (left)	1.9	4.4	10.8	1.9	-0.5	-2.5	-2.1	-2.8	-2.0	-1.9	-3.3	-2.7	-0.5	-2.8	-1.8	0.4	-0.9	-1.4	-1.7	-2.9
Tinnitus: Yes, but not now, but have in the past	0.3	0.3	2.5	0.5	-0.5	-0.1	-0.3	-0.2	1.6	0.2	-0.4	0.5	0.5	-0.3	0.6	-0.3	-0.1	-0.2	0.6	-0.4
Qualifications: CSEs or equivalent	0.2	0.3	1.3	0.6	-0.1	-0.0	-0.5	-0.2	1.1	0.1	-0.2	-0.6	0.2	-0.3	-1.1	-0.6	-0.3	-0.3	-0.6	-0.3
Serious illness, injury or assault to yourself	2.5	3.0	7.3	-1.8	-1.1	2.4	1.6	2.7	-0.3	2.1	2.6	1.0	1.2	1.8	1.5	-1.0	0.1	-0.3	2.0	2.6
High blood pressure	0.9	2.5	6.4	0.3	0.8	-2.3	-0.3	-2.4	-1.9	-2.5	-1.6	-1.5	-1.8	-1.9	-1.5	-0.5	-0.9	-0.4	-1.4	-1.6
Hayfever, allergic rhinitis or eczema	3.1	6.7	18.1	-1.8	0.7	3.3	3.5	4.2	1.8	2.8	3.3	2.8	0.8	3.2	2.5	-0.6	1.1	1.5	2.6	3.2
Multivitamins +/- minerals	0.6	0.8	3.3	1.0	-1.7	0.0	-0.8	-0.0	-1.8	-0.1	-0.2	0.6	-0.4	-0.3	-0.3	-1.7	-0.8	-0.6	1.0	0.2
Stomach or abdominal pain in last month	5.0	6.2	12.6	-1.9	0.6	3.3	2.5	3.5	0.6	3.1	2.8	2.6	0.4	3.0	3.1	1.4	2.9	2.4	2.3	2.7
Supplements: Glucosamine	0.3	0.4	3.7	-0.6	-0.4	-0.1	0.4	0.2	-1.9	-0.4	0.7	1.1	-0.1	0.4	-0.1	-0.5	0.3	-0.2	0.3	0.6
Diverticular disease/diverticulitis (self-reported)	0.6	0.7	4.3	0.3	-0.2	-0.3	0.1	-0.4	-1.3	-0.9	0.3	-0.6	-2.1	-0.0	-0.6	-1.5	0.8	-0.0	1.1	0.2
Medication: Atenolol	0.4	0.5	1.8	0.3	1.1	-0.1	-0.7	-0.5	0.1	0.3	-0.8	-0.2	1.3	-0.3	0.0	-0.0	0.5	-0.9	1.3	-0.6
Medication: Levothyroxine sodium	0.4	0.7	3.1	-0.9	1.1	-0.1	-0.2	-0.2	-1.5	0.2	-0.8	-0.3	-0.1	-0.1	-0.4	-1.8	-1.0	-1.1	1.4	-0.5
Sitting height	0.3	2.4	13.4	-0.8	3.0	0.3	0.2	0.9	3.0	-0.3	0.9	1.2	0.2	0.4	-0.5	-3.7	-0.7	-0.4	1.9	0.8
Chronic bronchitis/emphysema (father)	1.0	1.2	11.2	0.2	0.9	0.2	0.5	0.3	0.5	0.6	-0.1	-1.0	-0.4	-0.3	-1.2	-2.2	-0.0	-3.4	-0.3	-0.2
High blood pressure (mother)	0.8	1.1	5.0	0.5	2.2	0.6	0.1	0.1	-1.2	1.4	-0.5	-1.1	1.8	0.2	-0.4	0.8	-1.4	-0.7	-1.7	-0.2
Body mass index (BMI)	1.1	4.7	11.7	3.2	0.5	-2.5	-1.3	-2.1	-0.8	-2.6	-1.8	-2.0	-1.3	-2.6	-3.4	-0.8	-2.4	-1.6	-3.2	-1.8
Impedance of leg (left)	0.4	2.0	6.1	-0.7	-1.7	1.4	0.1	0.9	-0.3	1.9	0.9	0.5	1.0	1.2	2.3	1.9	2.5	1.1	2.0	0.8
Leg predicted mass (left)	0.5	2.6	11.0	-0.4	3.3	-0.6	0.2	0.3	3.0	-1.3	0.6	0.7	-0.7	-0.3	-1.8	-2.9	-2.6	-0.8	-1.0	0.6
Trunk fat mass	0.5	2.2	7.0	1.6	1.7	-1.5	-0.4	-1.1	0.4	-1.9	-0.6	-0.4	-1.2	-1.4	-2.5	-1.3	-2.6	-1.0	-2.0	-0.8
Waist circumference	0.6	2.3	6.3	1.9	1.5	-1.7	-0.1	-1.4	1.1	-2.4	-0.7	-0.2	-1.8	-1.5	-2.5	-1.9	-1.5	-0.9	-1.3	-0.8
Number of incorrect matches in round	0.6	1.0	5.7	-2.4	0.6	0.8	0.5	1.0	0.3	0.6	0.9	-0.1	-0.6	0.8	-0.1	-1.5	-1.2	-1.4	0.1	0.9
Past tobacco smoking	0.8	1.4	5.8	2.4	-0.7	-0.5	-0.9	-0.5	-0.5	0.2	-1.3	-1.0	1.7	-0.9	-1.0	-0.4	-1.6	-1.8	-0.8	-1.1
Alcohol usually taken with meals	1.1	1.9	5.9	-2.3	1.2	0.8	1.3	1.0	-0.7	0.8	0.8	2.4	0.8	1.7	1.6	-0.1	-0.0	1.7	2.0	1.0
Nervous feelings	1.1	2.0	4.9	-1.0	0.3	1.5	1.9	1.8	0.8	1.1	2.2	0.7	1.6	1.6	1.4	0.2	0.6	0.5	1.9	2.1
Frequency of tenseness / restlessness in last 2 weeks	0.4	0.7	3.5	1.9	0.5	0.7	0.7	0.4	1.2	1.1	0.5	-0.5	1.2	0.2	-0.2	1.2	-0.2	0.3	-0.5	-0.1
Hearing difficulty/problems with background noise	0.4	0.7	2.1	-0.3	-0.6	1.1	0.8	1.2	1.5	0.7	1.0	0.2	0.2	0.8	0.2	-0.7	0.1	-1.2	-0.0	1.1
Hair/balding pattern: Pattern 2	0.2	0.3	2.0	0.3	-0.9	-0.2	-0.2	0.2	0.7	-0.2	-0.2	-0.4	0.1	0.1	-0.6	-1.0	0.3	-1.4	-0.1	0.1
Had menopause	0.2	0.3	1.4	0.4	-0.8	-0.4	-0.2	0.0	-0.7	-0.4	0.0	0.1	-0.6	0.0	0.2	-0.5	0.4	-1.2	0.6	-0.2
Had other major operations	2.7	3.3	9.0	-1.7	-0.6	1.9	2.7	2.6	-0.7	1.0	3.0	1.7	0.3	2.0	1.3	-1.0	1.1	0.7	2.8	2.3
Forced vital capacity (FVC)	0.3	1.2	3.7	-1.6	1.4	0.7	0.4	1.3	0.6	0.3	1.0	1.2	-0.0	1.0	0.8	-1.9	0.4	1.0	1.7	1.1
Heel bone mineral density (BMD) T-score, automated (right)	1.9	4.3	12.3	2.2	-0.1	-2.3	-1.9	-2.9	-1.8	-1.6	-3.5	-2.5	-0.2	-2.7	-1.8	0.8	-1.4	-1.2	-1.7	-3.0
Ever unenthusiastic/disinterested for a whole week	0.1	0.2	1.3	-0.2	-1.1	-0.1	-0.1	-0.2	-0.4	-0.3	0.3	0.3	0.4	0.2	0.2	-0.3	0.0	0.3	0.6	0.1
Qualifications: None of the above	0.3	0.6	2.1	0.5	0.6	-0.5	0.7	-0.4	1.1	-0.9	0.1	-0.1	-1.4	-0.5	-0.3	-0.3	0.9	-1.4	0.8	0.1
Financial difficulties in last 2 years	1.7	2.2	5.9	-1.3	-0.4	2.0	1.1	2.4	1.0	1.8	2.3	0.7	1.3	2.1	1.0	0.3	-0.5	1.5	0.5	2.2
Mouth/teeth dental problems	0.3	0.5	1.6	0.1	0.6	-0.7	0.1	-0.8	-0.7	-0.9	-0.6	-1.1	-0.8	-0.9	-0.7	-1.3	0.5	-0.7	0.4	-0.1
Heart attack	2.1	2.7	4.9	-1.8	1.9	1.9	1.5	2.2	2.0	1.8	1.6	1.3	-0.3	1.7	1.4	-1.1	1.8	0.3	2.1	1.8
Allergy	0.7	1.6	4.8	0.8	-1.0	-1.6	-1.8	-1.9	-2.2	-1.3	-1.2	-1.1	-0.3	-1.2	-0.9	1.2	0.1	0.2	-1.4	-1.3
Pain all over the body in last month	1.0	1.1	3.7	-0.5	0.6	0.9	1.9	1.1	1.5	0.1	1.8	0.2	-0.1	1.0	0.9	-0.5	0.3	-0.7	1.4	1.5
Diabetes (self-reported)	1.1	1.7	3.5	0.7	1.4	-1.7	-0.3	-1.9	-0.6	-1.7	-1.6	-0.4	-0.9	-1.7	-1.5	-1.5	1.6	-0.9	1.0	-1.4
Hayfever/allergic rhinitis (self-reported)	0.7	1.0	2.6	-0.7	-0.2	1.2	1.3	1.6	-0.4	0.4	1.6	0.8	0.3	1.3	0.8	-0.4	0.0	0.4	1.2	1.6
Medication: Ramipril	1.2	1.5	3.8	1.0	-0.0	-1.7	-0.4	-1.4	-0.4	-1.9	-1.3	-0.7	-1.7	-1.3	-1.7	-1.1	-0.5	-0.8	-1.8	-1.1
Medication: Simvastatin	0.5	0.7	4.4	0.1	0.2	-0.5	0.2	-0.2	-0.9	-0.4	-0.2	-0.1	-0.8	-0.4	-0.5	-1.7	1.3	-2.1	0.5	-0.1
Fluid intelligence score	0.4	0.7	4.1	0.4	-0.4	-1.0	-0.4	-0.6	-0.8	-0.6	-0.7	-0.8	0.9	-0.6	-0.6	-0.9	2.0	-1.1	0.5	-0.8
Illnesses of siblings	0.6	0.9	2.7	-0.0	1.6	1.0	0.2	0.6	-0.4	1.5	0.2	0.1	1.2	1.1	1.3	1.6	0.6	1.0	-0.1	0.2
Neuroticism score	2.0	4.1	9.9	-1.3	1.3	2.3	3.1	2.8	0.7	2.1	2.8	1.5	1.2	2.1	2.3	0.9	2.1	1.4	1.9	2.5
Weight	0.5	2.5	7.7	1.4	2.8	-1.3	-0.5	-0.7	1.8	-1.8	-0.5	-0.3	-0.7	-1.3	-2.5	-2.0	-2.6	-1.1	-1.8	-0.6
Impedance of arm (right)	0.9	4.1	8.5	-1.4	0.2	2.6	2.1	2.3	-0.6	2.8	1.8	2.7	1.6	2.6	2.9	0.7	1.8	1.9	2.0	1.9
Arm fat percentage (right)	0.9	3.5	9.1	3.0	0.7	-2.0	-0.7	-1.7	-1.5	-2.1	-1.6	-1.0	-0.8	-2.0	-3.0	-0.8	-2.3	-1.1	-2.9	-1.7
Trunk fat-free mass	0.4	2.4	11.2	-0.3	3.3	-1.0	-0.8	-0.4	3.3	-1.3	-0.2	0.0	-0.0	-0.8	-1.8	-2.3	-2.2	-0.6	-0.3	-0.3
Hip circumference	0.4	1.9	6.7	1.6	2.6	-1.1	-0.5	-0.8	0.8	-1.3	-0.5	-0.8	-0.6	-1.2	-2.2	-1.6	-2.1	-1.1	-1.9	-0.4
Time employed in main current job	1.2	1.4	3.3	1.0	-0.7	-1.3	-1.2	-1.7	-1.2	-1.0	-1.5	-1.1	-0.2	-1.4	-1.1	0.8	-0.9	-1.1	-1.8	-1.3
Alcohol intake versus 10 years previously	0.2	0.3	1.4	-0.8	0.3	0.1	0.1	0.1	-0.0	-0.2	0.4	1.1	-0.2	0.1	0.0	0.7	0.6	1.2	0.5	0.5
Father’s age at death	0.4	0.5	2.3	0.0	-0.7	-0.7	-0.5	-0.7	0.3	-0.8	-0.0	-0.5	-0.3	-0.3	-0.3	-1.0	0.7	-1.5	1.2	-0.2
Worrier / anxious feelings	1.6	3.1	6.1	-1.5	1.5	2.1	2.5	2.0	1.3	2.0	1.7	1.1	-0.0	2.0	2.3	1.4	2.4	1.5	0.7	1.9
Frequency of tiredness / lethargy in last 2 weeks	1.9	3.0	7.3	-0.7	1.4	2.5	2.7	2.5	0.1	2.5	2.0	1.5	1.1	1.8	1.6	0.1	0.6	-0.8	2.2	2.0
Falls in the last year	0.4	0.5	1.1	-0.6	0.6	0.9	0.3	0.9	0.2	0.9	0.4	-0.3	0.5	0.5	1.1	0.9	-0.8	0.9	-0.3	0.7
Hair/balding pattern: Pattern 3	0.3	0.4	1.5	1.0	-0.0	0.6	0.1	-0.4	-1.2	0.7	0.5	0.2	-0.5	0.2	-0.1	0.8	1.2	0.4	-0.1	0.3
Number of live births	1.0	1.4	6.0	0.0	-1.3	-1.0	0.3	-0.6	1.1	-1.7	0.2	0.5	-2.5	-0.9	-0.0	-2.3	1.2	-1.5	1.0	0.3
Forced expiratory volume in 1-second (FEV1)	0.4	1.5	3.1	-1.7	0.8	1.1	0.5	1.8	0.4	0.7	1.4	1.5	0.5	1.4	1.2	-1.2	0.6	1.4	1.6	1.5
Pulse rate	3.5	6.0	10.8	3.1	-1.7	-3.1	-2.0	-3.1	0.5	-2.9	-2.7	-3.0	-2.5	-3.3	-3.2	-1.6	-0.6	-1.1	-1.1	-2.8
Happiness	3.0	3.7	10.0	-1.9	1.8	1.9	2.7	1.6	-0.7	1.8	2.2	3.2	1.2	2.3	2.3	0.8	-0.7	1.9	1.5	2.1
Noisy workplace	0.8	1.0	3.8	1.8	0.3	0.1	-0.9	-0.3	-0.0	0.4	-0.9	-1.3	1.0	-0.7	-0.8	1.3	-1.4	-0.7	-1.9	-0.5
Qualifications: A levels/AS levels or equivalent	1.5	3.4	7.3	-0.7	2.0	2.3	2.7	2.4	-1.2	2.3	2.5	1.3	1.8	2.5	1.2	-0.4	1.4	0.8	1.6	2.0
Serious illness, injury or assault of a close relative in last 2 years	0.3	0.4	4.2	0.8	-0.1	-0.2	0.0	-0.5	-0.1	-0.4	0.1	0.0	-0.7	0.1	0.3	0.2	-0.5	-0.1	-2.0	0.3
Mouth/teeth dental problems: Dentures	0.6	1.1	3.1	0.9	-0.8	-1.0	-1.4	-0.8	0.0	-0.5	-1.4	-1.5	0.0	-0.9	-0.7	0.2	-0.5	-1.8	-1.2	-1.5
Asthma	0.6	1.3	5.4	-0.3	0.5	-1.2	-0.5	-1.4	0.5	-1.4	-0.8	-0.7	-0.9	-1.2	-1.2	-2.1	-0.5	-2.3	-0.2	-0.5
Medication: Ibuprofen (e.g. Nurofen)	3.9	5.0	12.0	-0.9	0.4	3.5	1.8	3.0	0.8	3.4	3.0	2.1	1.8	3.1	2.1	-0.4	0.9	-0.4	2.5	2.9
Medication: Cholesterol lowering	0.3	0.4	1.6	-0.5	-0.2	-0.3	0.2	-0.5	-1.3	-0.6	0.1	0.6	-1.1	-0.2	-0.8	-1.1	-0.2	-1.0	0.2	0.1
Depression (self-reported)	1.6	2.0	4.3	-2.1	-1.1	1.5	0.6	1.9	0.5	1.1	2.0	1.2	1.1	2.1	1.7	0.0	0.1	1.2	0.8	2.0
Medication: Lansoprazole	0.7	0.8	3.3	0.0	-1.7	0.1	0.1	0.1	-1.8	-0.4	0.8	0.9	-1.6	0.0	0.2	-0.9	1.3	0.0	0.7	0.8
Prospective memory result	0.2	0.3	1.7	0.3	-0.5	0.1	-0.6	-0.7	1.3	0.0	0.0	0.6	0.6	-0.3	-0.3	0.3	-0.6	-0.2	0.3	-0.1
Lung cancer (father)	0.6	0.7	1.5	0.0	-0.9	-1.0	-1.1	-0.8	0.6	-0.8	-1.2	-0.1	-0.9	-0.8	-0.4	-0.7	-1.0	0.8	-0.8	-1.0
Illnesses of mother	0.6	0.8	3.0	-0.8	-1.7	0.1	0.2	0.3	0.7	0.1	0.3	0.9	0.5	0.3	1.2	1.7	0.7	1.6	0.6	-0.0
Forced expiratory volume in 1-second (FEV1), Best measure	0.9	2.8	6.3	-2.0	-0.2	1.7	0.9	2.5	0.6	0.9	2.3	1.8	0.6	1.9	1.9	-1.2	1.1	1.9	2.1	2.3
Pulse wave Arterial Stiffness index	0.6	0.7	3.7	-0.0	0.8	0.2	-0.1	0.2	0.1	0.2	0.3	-1.8	-0.9	-0.2	-0.2	-1.7	0.5	-1.9	-0.0	0.5
Impedance of arm (left)	1.0	4.5	8.9	-1.6	-0.4	2.9	1.8	2.6	-0.7	3.0	2.2	2.5	1.6	2.9	2.9	0.7	1.9	1.7	2.1	2.2
Arm fat mass (right)	0.8	3.4	9.0	2.7	1.5	-2.1	-0.8	-1.6	-0.1	-2.4	-1.4	-0.9	-1.1	-2.1	-3.0	-1.4	-2.3	-1.1	-2.5	-1.5
Trunk predicted mass	0.4	2.3	10.9	-0.3	3.3	-0.9	-0.8	-0.3	3.2	-1.3	-0.1	0.1	-0.0	-0.8	-1.7	-2.3	-2.2	-0.5	-0.3	-0.3
Standing height	0.8	7.5	29.7	-3.5	4.6	1.9	1.4	2.5	5.5	1.3	2.6	3.4	0.9	2.3	1.5	-2.9	-0.9	1.2	2.8	2.3
Length of working week for main job	0.4	0.4	2.4	1.4	-0.3	0.4	-0.1	0.7	-0.1	0.4	0.2	-0.8	0.3	-0.1	-0.7	0.4	-1.6	-0.3	-0.8	0.1
Exposure to tobacco smoke at home	0.7	0.8	5.1	1.1	-0.4	0.1	-0.7	0.2	2.3	0.4	0.1	-0.7	0.4	-0.1	0.3	-0.1	1.4	-1.3	1.3	0.1
Breastfed as a baby	1.0	1.2	4.4	-0.8	1.0	0.3	1.6	-0.1	-1.4	0.1	0.6	1.0	0.2	0.7	2.1	1.5	0.8	1.2	1.9	0.7
Tense / ‘highly strung’	1.2	2.0	6.3	-1.3	0.2	1.4	1.6	1.9	2.2	1.2	2.1	0.2	0.7	1.4	1.0	1.0	2.5	1.0	0.8	1.4
Seen doctor (GP) for nerves, anxiety, tension or depression	1.1	1.8	8.1	-0.4	-1.2	1.3	1.8	1.9	0.6	0.6	1.8	0.5	1.0	1.3	1.0	-0.1	1.0	0.1	2.8	1.6
Hair/balding pattern: Pattern 4	0.7	1.7	7.3	-2.7	0.3	1.5	1.2	1.6	1.0	1.1	1.8	1.2	-0.4	1.5	0.9	-1.1	-0.7	-0.6	0.4	1.7
Birth weight of first child	1.2	2.2	3.8	-0.9	0.3	1.7	1.2	1.9	2.0	1.4	1.7	1.9	1.0	1.8	1.7	-0.0	1.3	1.0	1.8	1.9
Peak expiratory flow (PEF)	0.2	0.4	1.5	-0.3	0.3	0.8	-0.0	1.2	-0.2	0.6	0.7	0.5	0.4	1.0	0.4	-0.9	0.1	0.2	0.3	1.0
Pulse wave reflection index	0.4	0.5	1.9	-0.5	-0.3	1.0	-0.1	1.1	-0.8	0.9	0.8	-1.0	0.4	0.6	0.0	-0.6	0.2	-1.4	0.1	0.7
Ever highly irritable/argumentative for 2 days	0.5	0.6	4.3	0.8	-2.1	-0.0	-0.1	0.0	-0.8	-0.1	0.4	0.3	1.1	0.0	0.2	0.8	0.2	0.7	1.0	0.2
Loud music exposure frequency	0.5	0.5	2.9	-1.7	-1.3	0.0	0.0	0.3	1.4	-0.5	0.7	0.1	-0.7	0.2	0.2	-0.3	-0.1	0.7	-0.0	0.6
Qualifications: O levels/GCSEs or equivalent	0.5	0.9	7.3	-0.2	0.3	1.1	-0.2	0.7	-0.2	1.6	0.5	-0.1	2.7	1.0	0.5	0.5	-0.3	1.0	0.3	0.3
Mouth/teeth dental problems: Bleeding gums	0.5	0.6	2.9	-0.0	-0.0	0.4	0.6	0.8	0.7	0.3	0.8	1.7	0.9	0.9	-0.0	0.9	-1.0	0.7	-0.8	0.3
Blood clot in the leg (DVT)	0.9	1.2	5.0	1.1	0.5	-0.6	-1.0	-0.7	2.2	-0.4	-1.2	-1.0	-0.5	-1.1	-0.8	-0.9	-2.2	-0.5	-1.0	-0.6
Medication: Paracetamol	1.6	2.6	5.1	-2.1	1.8	1.5	1.6	1.9	0.6	1.8	1.6	2.3	1.2	1.6	2.1	-0.2	1.4	0.2	2.2	1.6
Headache pain in last month	1.9	3.2	6.7	-1.3	-0.5	2.6	1.0	2.6	-0.1	2.5	2.3	1.2	2.1	2.1	2.0	0.7	1.1	1.0	2.2	2.3
Medication for cholesterol, blood pressure or diabetes	0.6	0.9	2.4	1.1	-1.0	1.4	-0.4	1.5	1.2	1.5	0.6	-0.5	1.5	0.7	1.0	-0.2	-0.0	0.2	0.6	0.7
Glaucoma (self-reported)	1.1	1.3	8.8	0.5	-3.0	0.3	-1.2	-0.2	-0.9	0.7	-0.4	-0.1	-0.8	-0.2	-0.0	-1.9	1.5	-1.4	1.5	-0.1
Gout (self-reported)	0.4	0.5	2.5	0.4	0.4	-0.7	0.4	-0.7	-1.3	-0.7	-0.3	-0.1	-1.6	-0.2	0.3	0.6	1.2	0.3	0.1	0.1
Hypothyroidism/myxoedema (self-reported)	0.4	0.8	3.6	-1.3	1.6	0.9	0.6	0.9	-1.0	0.7	0.6	0.3	-0.4	0.8	-0.0	-1.9	-0.6	-0.4	0.7	0.8
Medication: Amlodipine	2.7	3.7	8.9	-0.0	-0.6	-3.0	-1.7	-2.7	-2.4	-2.8	-2.9	-1.5	-0.9	-2.5	-1.6	0.3	-1.2	-0.4	-1.2	-2.6
Medication: Ventolin 100micrograms inhaler	0.4	0.5	1.9	-0.0	1.1	-0.3	-0.7	-0.6	0.9	0.0	-1.0	-0.5	1.0	-0.8	-0.6	-0.3	0.5	-1.4	0.1	-0.7
Birth weight	0.4	1.0	4.2	0.5	0.2	0.9	1.0	0.6	-0.7	0.7	1.0	2.0	1.2	0.9	1.0	0.5	0.8	0.6	1.7	0.5
Chronic bronchitis/emphysema (mother)	1.5	1.8	6.3	2.5	-1.6	-1.2	-0.4	-0.6	0.4	-1.4	-0.7	-1.7	-1.0	-1.5	-1.1	-2.1	0.5	-1.9	0.9	-0.7
High blood pressure (siblings)	0.7	1.0	5.4	-1.0	-2.3	-0.7	-0.2	-0.1	1.0	-1.4	0.4	0.0	-2.1	-0.4	-0.6	-0.8	-0.1	0.4	-0.7	0.3
Forced vital capacity (FVC), Best measure	0.8	2.9	6.5	-2.1	0.4	1.5	0.9	2.3	1.2	0.7	2.3	1.9	0.2	1.9	1.7	-2.0	0.7	1.6	2.6	2.3
Body fat percentage	0.8	3.1	7.8	2.7	0.4	-1.9	-1.0	-1.7	-0.9	-2.1	-1.4	-1.2	-1.2	-2.0	-2.8	-0.5	-2.3	-1.2	-2.6	-1.5
Leg fat percentage (right)	1.8	6.4	16.1	4.0	-0.4	-2.9	-2.2	-3.0	-1.2	-2.8	-2.6	-2.5	-1.2	-3.1	-3.6	0.0	-2.1	-1.4	-3.1	-2.8
Arm fat-free mass (right)	0.5	2.4	11.3	-0.4	2.7	-1.0	-0.7	-0.4	3.4	-1.5	0.1	-0.2	-0.8	-0.7	-1.8	-2.5	-2.2	-1.4	-0.8	0.1
Exposure to tobacco smoke outside home	0.2	0.3	1.8	-0.2	0.0	-0.4	-0.4	-0.1	0.5	-0.3	-0.4	-0.8	-0.0	-0.5	-0.5	-0.9	0.2	-1.3	0.1	-0.3
Comparative body size at age 10	0.1	0.2	1.1	0.2	0.1	-0.4	0.4	-0.1	-0.1	-1.1	0.5	-0.6	-1.1	0.1	-0.3	-0.0	-0.3	0.5	-0.3	0.4
Number of full brothers	0.6	0.8	4.1	-0.1	0.2	0.7	1.0	1.0	2.0	0.9	0.8	0.3	0.5	0.6	0.8	0.8	1.4	-1.2	-0.0	0.7
Worry too long after embarrassment	0.4	0.7	2.8	-0.3	0.3	0.9	1.1	0.8	1.2	0.7	1.0	0.1	0.8	0.5	0.7	1.7	1.0	0.8	-0.7	0.7
Seen a psychiatrist for nerves, anxiety, tension or depression	1.4	1.8	4.4	-1.6	-0.9	1.4	0.4	1.7	-0.2	1.4	1.5	1.5	1.3	1.7	1.3	0.7	0.7	2.1	1.3	1.2
Wheeze or whistling in the chest in last year	0.9	1.6	3.5	-0.7	1.0	1.6	1.5	1.1	1.4	1.3	1.7	1.2	-0.0	1.2	0.9	-0.9	0.8	-1.2	1.6	1.9
Number of children fathered	0.5	0.5	4.1	-2.0	-0.3	-0.4	-0.5	-0.8	0.2	-0.5	-0.5	0.4	-0.9	-0.3	0.2	0.0	-0.7	1.1	-0.6	-0.2
Reason for reducing amount of alcohol drunk: Health precaution	0.8	0.9	2.7	0.7	0.7	-1.0	-0.7	-0.8	-0.7	-0.8	-1.7	-0.8	-0.4	-1.2	-1.3	0.5	-0.7	-0.2	-1.0	-1.4
Age at first live birth	0.7	1.2	5.4	-2.3	1.6	1.1	0.3	0.9	0.1	1.5	0.7	0.4	1.3	1.5	0.5	0.8	-0.2	1.6	-0.2	0.6
Pulse wave peak to peak time	0.6	0.7	4.0	-0.3	-0.4	0.0	0.1	-0.1	0.3	-0.0	-0.1	2.0	1.0	0.3	0.3	1.7	-0.5	2.0	0.2	-0.3
Health satisfaction	0.8	1.0	4.6	1.0	1.3	0.7	0.8	0.2	-0.7	0.8	0.2	0.9	1.2	0.3	0.6	1.6	-2.2	0.5	-1.2	0.4
Shortness of breath walking on level ground	0.2	0.2	0.6	0.6	0.2	-0.2	0.5	-0.1	-0.5	-0.8	0.4	0.2	-0.5	-0.3	-0.6	-0.7	-0.2	-0.2	-0.2	0.5
Qualifications: College or University degree	0.3	1.0	2.5	-0.1	0.4	1.3	0.9	1.6	-1.2	1.6	1.0	1.3	0.2	1.6	0.8	-1.1	-0.0	-0.5	0.0	1.1
Eye problems/disorders: None of the above	0.7	0.8	2.9	-0.7	0.5	0.5	0.3	0.8	-1.2	0.5	0.6	-0.5	0.7	0.7	0.7	1.7	-0.1	1.4	-1.7	0.7
Mouth/teeth dental problems: Loose teeth	1.2	1.4	4.9	1.1	-1.5	-0.8	-1.2	-0.1	1.3	-0.9	-0.2	-1.5	-1.0	-1.0	-2.0	-2.2	-0.9	-1.2	0.1	-0.7
Emphysema/chronic bronchitis	0.5	0.5	4.5	-1.0	0.3	0.4	0.3	0.4	0.3	0.1	0.5	-0.7	0.0	0.2	-0.1	0.9	-2.1	-0.5	-0.9	0.4
Medication for pain relief, constipation, heartburn	1.8	3.1	6.6	2.0	-1.2	-1.9	-1.8	-2.0	0.2	-1.8	-1.8	-2.6	-1.7	-2.1	-2.1	-0.2	-1.6	-0.0	-2.6	-1.7
Neck or shoulder pain in last month	0.7	1.1	3.7	1.9	1.5	1.1	1.0	0.5	0.2	1.4	-0.2	0.4	1.0	0.4	-0.6	0.5	-1.8	-1.4	-0.3	0.2
Medication: Blood pressure	1.2	2.1	5.6	-1.0	1.8	-2.3	0.0	-2.4	-0.9	-2.3	-1.6	0.2	-1.8	-1.3	-0.9	0.8	0.6	0.8	-0.6	-1.8
Angina (self-reported)	0.6	0.8	6.4	0.6	0.8	-0.3	0.2	-0.0	-1.1	-0.4	-0.3	0.0	-0.8	-0.6	-0.9	-2.5	-1.3	-0.6	0.8	-0.3
Migraine (self-reported)	0.9	1.1	3.8	-1.9	0.2	1.5	0.8	1.4	0.2	1.2	1.6	1.0	0.4	1.4	0.7	0.0	-0.5	-0.3	0.0	1.4
Medication: Ibuprofen	5.4	6.5	12.2	-1.6	1.2	3.5	2.5	3.4	1.0	3.2	3.5	2.2	1.6	3.4	2.8	-0.3	2.2	0.2	3.3	3.3
Medication: Allopurinol	0.4	0.5	2.3	0.9	0.6	-0.1	0.5	-0.4	-1.5	-0.1	-0.1	0.5	-0.3	0.0	0.5	1.4	-0.2	1.3	0.1	0.0
Medication: Omeprazole	1.6	1.9	4.1	-1.6	1.2	1.8	1.5	1.8	-0.5	1.6	1.4	2.0	-0.5	1.8	0.7	-1.4	-0.3	0.1	1.8	1.3
Medication: Seretide 50 evohaler	0.3	0.3	2.3	-0.1	-0.5	-0.1	-0.1	-0.4	0.3	-0.7	0.4	0.4	-0.7	-0.1	-0.6	-1.5	-0.2	-0.9	0.6	0.4
Mean time to correctly identify matches	0.3	0.5	2.6	-1.0	0.9	-0.7	0.5	-1.2	0.8	-0.5	-0.5	0.1	-0.6	-0.4	0.2	1.6	0.2	0.2	0.1	-0.8
Heart disease (mother)	0.7	0.8	4.8	-1.1	0.4	-0.3	0.2	0.0	2.2	-0.5	0.2	-0.4	-0.6	-0.2	-1.4	-0.4	-1.0	-1.2	-1.3	0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.7	0.8	3.9	2.0	-0.2	-0.3	0.3	-0.5	-0.3	0.2	-0.9	-1.2	0.2	-0.6	-0.2	1.1	-1.7	-0.9	-1.1	-1.0
Whole body fat mass	0.7	2.9	7.8	2.1	1.3	-1.8	-0.7	-1.4	0.5	-2.2	-1.0	-0.7	-1.4	-1.8	-2.8	-1.4	-2.7	-1.1	-2.2	-1.1
Leg fat mass (right)	0.9	3.4	9.0	2.5	1.0	-2.2	-1.2	-1.9	0.3	-2.6	-1.3	-1.3	-1.2	-2.2	-3.0	-0.9	-2.4	-1.0	-2.4	-1.6
Arm predicted mass (right)	0.5	2.5	11.1	-0.1	2.5	-1.0	-0.9	-0.4	3.3	-1.5	0.0	-0.3	-1.0	-0.9	-2.0	-2.7	-2.2	-1.6	-0.7	-0.0
Pulse rate, automated reading	2.1	6.9	14.7	3.3	-3.3	-3.4	-3.0	-3.8	1.7	-3.1	-3.0	-2.1	-1.9	-3.4	-2.4	-1.4	-0.5	-1.0	-0.5	-3.1
Alcohol intake frequency.	0.3	0.7	3.0	1.3	-0.8	-0.5	0.1	-0.5	0.1	-0.9	0.2	-0.1	-0.7	-0.4	-0.6	-1.4	1.4	-1.7	0.8	0.3
Comparative height size at age 10	0.8	4.4	34.7	-3.7	5.9	0.7	0.2	1.1	3.5	0.3	0.8	1.7	0.7	0.8	0.7	-2.0	-0.5	0.7	1.4	0.6
Number of full sisters	2.4	3.0	6.7	-1.4	2.5	2.6	1.9	2.4	0.7	2.5	2.0	1.5	1.1	2.1	1.7	-0.3	0.2	-0.6	0.9	2.1
Suffer from ‘nerves’	2.0	3.1	7.8	-1.4	0.6	2.0	1.5	2.1	0.6	2.0	2.1	1.3	1.6	2.2	2.2	0.1	2.8	0.7	2.1	1.9
Overall health rating	0.3	0.6	2.0	-0.5	1.4	0.8	0.8	0.6	0.3	0.8	0.4	0.8	1.1	0.5	0.1	0.2	-1.4	-0.8	0.4	0.4
Chest pain or discomfort	3.4	5.0	12.8	-1.9	2.3	3.0	3.6	3.0	1.1	2.7	3.0	1.6	-0.2	2.4	2.3	-0.4	0.8	-0.5	2.4	2.8
Had major operations	1.2	1.5	5.5	-0.2	0.6	-1.3	-0.3	-1.2	0.3	-1.6	-0.5	-1.3	-2.1	-1.1	-1.6	-2.3	-0.2	-1.8	0.5	-0.3
Age at last live birth	1.4	2.0	5.2	-1.8	0.1	2.2	-0.0	2.1	0.8	2.3	1.8	0.6	1.6	2.0	0.4	-1.0	-0.1	0.5	0.9	1.7
Family relationship satisfaction	0.8	1.0	2.6	-1.4	1.0	0.9	1.3	1.2	0.5	0.6	1.3	0.1	-0.3	1.1	0.6	-1.1	-1.6	-0.1	0.5	1.5
Leg pain on walking	1.2	1.5	3.9	-0.9	1.1	1.5	1.5	1.2	0.2	1.0	1.5	2.0	0.4	1.4	1.6	1.4	0.6	0.8	0.2	1.7
Qualifications: NVQ or HND or HNC or equivalent	0.6	0.7	4.2	0.5	-0.6	-0.5	-0.8	-0.3	0.8	-0.7	-0.4	-0.3	-0.3	-0.3	-0.5	1.4	-0.4	2.1	-1.4	-0.6
Commuting to job workplace: Car/motor vehicle	0.4	0.5	1.5	-0.4	-0.7	1.0	0.2	1.2	-0.1	0.8	1.1	-0.4	0.3	0.6	-0.1	-0.3	-1.2	-0.3	0.3	1.0
Illness, injury, bereavement, stress in last 2 years	1.9	2.3	7.2	1.3	0.3	-1.7	-2.1	-2.2	-0.2	-1.0	-2.7	-1.9	0.3	-2.1	-1.1	0.0	-0.4	-1.2	-0.4	-2.5
Medication: Aspirin	0.2	0.2	0.7	-0.2	0.7	-0.5	0.2	-0.4	-0.8	-0.5	-0.6	-0.0	0.4	-0.2	0.2	0.5	0.1	-0.1	0.7	-0.3
Supplements: Vitamin C	0.3	0.3	1.5	1.2	-0.8	0.6	0.6	0.6	0.2	0.4	0.6	0.0	-0.9	0.4	0.4	0.6	-0.3	0.6	-0.1	0.4
Knee pain experienced in last month	2.2	3.4	8.2	-1.2	0.8	2.6	1.8	2.9	1.2	2.7	2.1	2.0	2.0	2.6	1.6	0.4	-0.7	-0.7	0.6	2.4
Hypertension (Self-reported)	0.7	1.8	4.4	0.6	0.8	-2.0	-0.3	-2.1	-1.9	-2.0	-1.5	-1.1	-1.2	-1.6	-1.3	-0.0	-1.0	-0.2	-1.3	-1.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.6	0.7	3.3	-0.7	-1.0	1.1	0.1	0.6	-1.0	0.5	1.1	1.8	-0.1	1.1	0.6	-0.1	0.2	0.1	1.2	0.9
Illnesses of father: Heart disease	0.3	0.5	1.8	-0.1	0.2	0.6	1.0	0.6	0.3	0.5	0.1	1.4	-1.1	0.5	0.3	-0.9	0.3	0.0	1.0	0.6
Illnesses of siblings: Diabetes	0.9	1.1	3.2	-0.3	1.2	-1.4	-0.2	-1.5	0.1	-1.4	-1.1	-0.6	-0.6	-1.2	-1.3	-1.6	0.1	-1.8	-0.5	-0.8
Smoking status: Previous	0.6	0.9	4.6	-2.1	0.9	-0.2	0.6	0.0	1.5	-0.7	0.6	0.4	-1.6	0.2	0.7	-0.2	1.1	1.4	0.9	0.5
Forced expiratory volume in 1-second (FEV1), predicted	2.3	4.8	9.4	-2.3	0.8	2.7	1.1	3.0	2.5	2.4	2.8	2.3	2.3	3.1	2.0	0.7	0.2	2.4	0.3	2.7
Whole body fat-free mass	0.5	2.6	11.2	-0.4	3.3	-0.9	-0.5	-0.2	3.3	-1.4	0.2	0.2	-0.4	-0.7	-1.9	-2.8	-2.3	-1.0	-0.7	0.1
Leg fat-free mass (right)	0.5	2.8	11.6	-0.6	3.4	-0.5	0.3	0.5	3.2	-1.2	0.8	0.5	-0.8	-0.2	-1.8	-3.2	-2.3	-1.1	-1.0	0.8
Arm fat percentage (left)	0.9	3.4	9.3	3.0	0.6	-1.8	-0.9	-1.6	-1.5	-2.0	-1.5	-1.1	-0.8	-1.9	-3.0	-0.7	-2.4	-1.3	-3.1	-1.5
Average weekly red wine intake	0.9	1.4	3.2	-1.2	1.6	1.2	0.7	1.5	1.2	1.2	1.4	1.0	1.8	1.6	0.5	-0.6	-0.9	0.8	0.3	1.3
Handedness (chirality/laterality): Left-handed	0.9	1.1	3.5	0.0	-0.4	-0.9	-1.9	-0.9	-1.4	-0.5	-1.4	-0.7	1.2	-0.8	-1.6	-0.2	-0.4	-1.6	-0.7	-1.2
Mood swings	1.3	2.4	9.0	-1.0	0.3	1.1	2.2	1.8	-0.4	0.8	1.3	1.0	0.2	1.0	2.1	-0.3	3.0	1.2	3.0	1.5
Loneliness, isolation	1.3	1.8	4.3	-0.3	-0.0	1.5	1.3	2.0	1.2	1.3	2.1	1.1	0.8	1.6	1.5	-0.8	0.8	-0.1	1.9	1.9
Long-standing illness, disability or infirmity	0.5	0.7	2.0	-0.6	1.4	0.9	0.9	1.1	-1.4	1.1	0.2	1.2	0.3	0.6	0.3	-0.9	-0.0	-0.4	0.5	0.4
Ever had bowel cancer screening	1.1	1.3	3.1	-0.7	1.8	1.3	1.8	1.4	-0.5	1.5	1.1	1.4	-0.1	1.2	1.5	0.4	0.3	-0.0	0.8	1.2
Diabetes diagnosed by doctor	0.5	0.8	2.1	0.2	1.5	-0.8	-0.0	-1.1	-0.6	-0.9	-1.0	0.4	-0.7	-0.8	-0.9	-1.3	1.4	-0.2	1.2	-0.7
Ever had stillbirth, spontaneous miscarriage or termination	0.3	0.3	1.3	-0.6	-0.0	-0.1	0.2	0.2	1.0	-0.0	-0.0	0.3	1.2	0.0	0.0	0.5	0.5	0.1	-1.2	0.0
Friendships satisfaction	2.0	2.5	4.8	-0.7	1.7	1.9	2.1	2.2	0.7	1.9	2.2	1.5	1.5	2.1	0.9	-1.3	-1.0	-0.6	0.9	2.0
Qualifications: nursing, teaching	0.5	0.8	3.6	-0.5	0.7	1.0	1.9	1.1	-0.5	1.2	0.6	0.9	0.7	1.2	0.7	0.2	-1.0	0.2	-0.0	1.1
Commuting to job workplace: Walk	0.4	0.4	2.9	-0.4	0.3	0.3	0.8	0.3	0.5	0.2	0.3	1.7	-0.1	0.6	0.8	-0.1	-0.3	1.0	-0.1	0.4
Eye problems/disorders: Cataract	0.7	0.8	3.6	-1.5	0.6	-0.3	0.7	-0.4	1.6	-0.8	-0.0	1.9	-1.4	0.1	0.2	-0.9	0.1	0.7	0.3	0.1
Mouth/teeth dental problems: Mouth ulcers	1.9	3.0	6.1	-1.3	0.4	2.3	1.6	1.8	0.7	2.0	2.0	2.5	1.5	2.2	2.1	1.5	0.5	2.4	1.1	1.6
Medication for cholesterol	0.4	0.7	3.1	-0.9	0.7	0.5	1.0	0.6	1.8	0.2	0.8	1.1	-1.0	0.5	0.6	0.3	0.9	0.6	0.7	0.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.4	0.4	3.5	-0.1	-1.9	-0.3	-0.3	-0.1	-1.3	-0.6	0.3	-0.3	-0.4	-0.1	0.2	-0.4	0.7	-0.5	0.4	0.1
Back pain experienced in last month	3.8	5.5	12.9	-3.0	2.1	3.4	1.7	3.6	0.8	3.5	2.8	2.2	1.8	3.0	2.1	-0.0	0.8	0.6	1.9	2.5
Mineral and other dietary supplements	1.2	1.6	4.5	1.5	1.0	-1.0	-1.0	-1.3	1.6	-0.5	-1.5	-1.8	0.6	-1.2	-1.3	0.8	-1.1	-1.1	-2.1	-1.4
Breast cancer (self-reported)	2.3	2.8	5.8	-1.5	0.2	2.2	1.9	2.3	0.6	2.3	1.7	2.4	1.3	2.2	2.0	0.9	-0.5	1.3	0.4	1.6
Asthma (self-reported)	0.6	1.1	5.0	-0.5	0.4	-1.1	-0.2	-1.2	0.8	-1.4	-0.6	-0.5	-0.9	-1.0	-1.1	-2.1	-0.4	-2.2	-0.1	-0.4
Osteoporosis (self-reported)	0.9	1.1	3.6	-1.3	1.9	0.9	1.5	0.9	0.6	0.8	1.0	1.1	0.7	1.1	0.9	-0.6	0.7	-1.0	0.5	1.1
Osteoarthritis (self-reported)	0.4	0.5	1.6	0.1	-1.2	0.7	0.2	1.0	-0.8	0.4	0.4	0.2	-0.7	0.7	0.3	-0.7	0.3	-0.7	1.3	0.4
Medication: Aspirin	0.3	0.4	0.9	0.3	0.6	-0.9	0.0	-0.7	-0.8	-0.9	-0.9	-0.1	-0.7	-0.6	-0.3	-0.2	0.0	-0.0	0.8	-0.7
Medication: Gliclazide	0.3	0.4	2.6	1.2	1.2	-0.1	0.3	-0.6	0.1	0.1	-0.7	0.1	0.3	-0.2	-0.1	0.1	1.6	0.0	-0.1	-0.4
Illnesses of father: None of the above (group 1)	0.8	1.0	5.3	-0.6	-0.1	1.0	0.3	1.1	-0.6	1.2	0.6	-0.0	2.3	1.0	1.4	2.0	-0.2	0.8	0.1	0.2
Smoking status: Current	0.5	0.8	4.0	0.8	-0.0	-0.9	-0.4	-0.8	-0.5	-1.0	-0.3	-0.2	-1.4	-0.5	-1.7	0.4	-0.5	-0.6	-2.0	-0.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.3	0.7	3.8	0.7	-1.9	-0.1	-1.4	0.0	-0.8	0.1	-0.4	-0.5	-0.1	-0.3	-0.2	-1.5	-0.8	-1.0	0.9	-0.2
Whole body water mass	0.5	2.6	10.9	-0.4	3.3	-0.9	-0.4	-0.1	3.3	-1.5	0.2	0.3	-0.5	-0.7	-1.9	-2.8	-2.3	-0.9	-0.7	0.1
Leg predicted mass (right)	0.5	2.7	11.6	-0.5	3.4	-0.5	0.4	0.5	3.1	-1.2	0.8	0.5	-0.8	-0.2	-1.7	-3.2	-2.3	-1.1	-0.9	0.8
Arm fat mass (left)	0.8	3.1	8.7	2.4	1.4	-1.9	-0.9	-1.4	-0.1	-2.3	-1.2	-0.9	-1.1	-1.9	-3.0	-1.5	-2.5	-1.3	-2.6	-1.2
Number of self-reported non-cancer illnesses	0.4	0.7	4.6	-0.8	0.8	-0.3	0.7	-0.0	-0.9	-0.6	0.4	-0.1	-0.1	0.2	-0.5	-1.8	-1.1	-2.1	0.1	0.4
Average weekly champagne plus white wine intake	1.2	1.7	5.2	-0.6	-0.1	1.5	1.2	1.5	-1.0	1.9	1.1	1.1	0.9	1.5	2.3	0.5	0.8	1.2	1.8	1.2
Miserableness	1.5	2.6	6.7	-1.6	-0.3	1.7	2.4	2.4	-1.1	1.0	2.6	1.5	-1.3	1.6	0.6	-1.5	0.7	0.0	1.7	2.4
Guilty feelings	2.5	3.8	6.0	-1.6	-0.1	2.2	2.0	2.3	2.5	1.9	2.3	2.2	0.8	2.1	2.2	1.5	1.9	1.9	2.0	2.2
Wears glasses or contact lenses	2.8	3.2	6.1	1.4	-1.9	-2.2	-2.1	-2.4	1.0	-2.3	-2.1	-1.5	-0.8	-2.5	-2.0	-1.2	0.9	-1.5	-0.4	-2.1
Ever taken oral contraceptive pill	0.4	0.5	3.5	-0.3	-1.0	-0.3	-0.3	-0.2	-0.9	-0.4	0.2	0.5	-0.8	-0.1	0.0	-1.1	1.9	-0.1	0.2	0.2
Hearing aid user	4.9	5.5	12.5	3.5	-1.3	-2.3	-2.6	-2.2	-2.6	-1.6	-2.7	-1.6	-1.3	-2.8	-3.1	-1.9	-1.3	-2.9	-1.6	-2.7
Mother’s age at death	1.1	1.4	4.8	1.2	-0.2	-1.4	-1.2	-1.4	-0.8	-1.1	-1.2	-0.8	-2.2	-1.3	-1.3	-1.3	-0.3	-0.3	0.0	-1.6
Financial situation satisfaction	0.3	0.4	1.8	-0.5	0.4	1.0	0.1	0.8	0.1	1.3	0.7	0.2	0.1	0.8	0.1	0.3	-0.9	-0.2	-0.8	0.7
Tinnitus: Yes, now most or all of the time	1.2	1.4	15.2	0.8	0.9	0.2	0.5	0.3	-0.1	0.3	0.2	0.8	-0.2	-0.2	-1.0	1.1	-3.9	1.2	-1.2	-0.5
Commuting to job workplace: Public transport	0.7	0.9	2.1	1.5	-0.0	-1.3	-1.3	-1.1	-0.2	-1.0	-1.4	-0.1	0.4	-0.8	-0.9	-0.6	0.8	-0.6	-0.9	-1.3
Eye problems/disorders: Glaucoma	1.0	1.1	6.0	1.5	-2.4	-0.0	-1.1	-0.4	-0.3	0.5	-0.6	-0.1	-0.6	-0.5	-0.9	-1.9	0.2	-1.7	0.7	-0.7
Medication: Blood pressure	0.3	0.5	3.1	0.2	0.8	-0.5	-0.4	-0.8	-1.8	-0.5	-0.4	-0.9	0.8	-0.4	-0.3	-0.6	0.2	-0.9	0.3	-0.2
Pain type(s) experienced in last month: Hip pain	1.0	1.3	3.2	-0.8	-0.2	1.7	0.3	1.5	-0.2	1.8	1.6	1.2	0.7	1.4	0.6	-0.6	-0.1	-0.3	1.8	1.6
Supplements: Fish oil (including cod liver oil)	0.7	0.9	2.9	-0.7	-1.7	0.5	0.2	0.9	-0.9	-0.1	1.1	0.9	-0.8	0.6	0.6	-1.1	0.7	0.5	1.7	1.1
High cholesterol (Self-reported)	0.4	0.8	3.1	-0.3	0.2	0.1	1.1	0.2	-1.0	-0.2	0.9	0.6	-1.2	0.7	-0.3	-1.8	0.7	-1.5	0.6	1.1
Medication: Bendroflumethiazide	1.9	2.9	6.5	-2.5	2.0	1.9	1.3	1.6	0.7	1.9	1.9	1.7	0.4	2.2	2.2	0.5	1.2	1.6	1.9	1.8
Medication: Paracetamol	3.2	4.9	10.5	-2.3	2.4	2.2	2.3	2.5	1.2	2.5	2.3	2.4	1.9	2.4	3.2	0.6	2.0	0.7	2.8	2.3
Medication: Lisinopril	0.5	0.7	4.8	0.4	0.9	-0.7	-0.1	-0.8	-0.1	-0.5	-0.8	0.1	-0.1	-0.6	0.8	0.8	2.2	-0.4	1.2	-0.4
Medication: Atorvastatin	0.6	0.8	2.7	-1.0	0.9	-0.1	-0.0	-0.5	-1.1	-0.2	0.1	-0.4	-0.2	-0.0	-1.2	-1.4	-1.6	-1.4	-1.2	0.4
Illnesses of father: High blood pressure	0.6	0.7	1.7	-0.3	0.1	-0.9	-0.7	-1.0	0.6	-1.1	-0.3	-1.0	-1.2	-1.0	-1.3	-1.1	-0.5	-0.6	-1.1	-0.2
Alcohol drinker status: Never	1.3	1.5	2.7	1.5	0.2	-1.3	-0.8	-1.6	0.9	-1.0	-1.2	-1.6	-0.0	-1.4	-1.2	1.1	-1.6	-1.2	-1.5	-1.4
Ever smoked	0.6	1.1	4.8	-1.7	0.0	0.7	0.4	0.8	0.1	0.1	1.3	0.5	-1.2	1.2	1.0	0.5	2.2	1.4	0.4	1.3
Basal metabolic rate	0.5	2.6	10.9	-0.0	3.3	-1.0	-0.4	-0.2	3.0	-1.6	0.1	0.0	-0.5	-0.8	-2.1	-2.7	-2.3	-0.9	-0.9	-0.0
Leg fat percentage (left)	1.5	5.3	13.8	3.7	-0.4	-2.6	-2.0	-2.5	-0.7	-2.6	-2.1	-2.4	-1.5	-2.8	-3.4	-0.1	-1.9	-1.4	-3.1	-2.4
Arm fat-free mass (left)	0.5	2.4	10.0	-0.1	3.0	-1.2	-0.5	-0.5	3.2	-1.8	0.0	-0.1	-0.9	-1.0	-1.9	-2.7	-1.7	-1.1	-0.5	-0.1
Number of operations (self-reported)	0.4	0.6	2.6	0.1	0.2	-0.4	1.6	0.0	-1.3	-0.9	0.6	0.6	-0.9	0.0	-0.0	-1.0	0.2	-0.5	1.2	0.3
Average weekly beer plus cider intake	1.6	2.3	11.2	3.4	-2.5	-1.3	-1.0	-1.4	1.7	-1.4	-1.1	-0.7	-0.9	-1.7	-1.5	0.8	1.0	-0.6	-0.8	-1.4
Irritability	0.9	1.5	3.8	-0.8	-0.1	1.4	1.7	1.9	-0.7	0.9	1.8	0.6	0.7	0.9	0.5	-1.6	1.2	-0.0	1.6	1.8
Risk taking	0.6	0.8	2.0	0.7	-0.8	-1.2	-0.4	-0.9	-0.4	-1.2	-0.6	-1.4	-0.1	-1.0	-1.4	-0.9	-0.9	-1.1	-0.6	-0.5
Ever had prostate specific antigen (PSA) test	1.0	1.2	5.8	-1.3	0.4	-0.1	0.2	-0.1	-2.2	-0.5	0.3	0.6	-1.4	-0.3	-0.8	-1.9	-2.4	0.0	0.6	-0.1
Fractured/broken bones in last 5 years	4.0	5.1	10.5	-2.4	2.1	2.9	3.0	2.5	-0.2	2.2	3.2	3.1	0.5	3.1	1.7	-0.1	0.5	0.8	2.0	3.2
Age started oral contraceptive pill	0.6	0.7	3.9	-2.0	-0.7	0.3	0.1	0.6	-0.2	-0.0	0.5	1.3	-0.4	0.8	1.2	-0.2	1.2	1.1	0.6	0.6
Diastolic blood pressure, automated reading	1.0	3.1	6.1	2.3	0.4	-2.2	-1.7	-2.3	0.1	-2.1	-2.4	-2.1	-0.8	-2.4	-2.1	0.2	-0.5	-0.3	-1.4	-2.5
Ever depressed for a whole week	0.8	1.0	3.1	-0.4	-0.6	1.5	0.3	1.8	0.8	1.2	1.6	0.8	0.6	1.6	0.8	-0.5	-0.0	0.6	0.6	1.4
Unable to work because of sickness or disability	0.4	0.5	1.9	-0.2	-0.3	0.5	0.4	0.2	-0.2	0.5	0.4	0.6	0.3	0.7	1.4	1.0	1.1	0.2	1.2	0.3
Commuting to job workplace: Cycle	0.5	0.6	2.4	0.6	-1.1	-1.0	-0.2	-0.3	-0.0	-1.1	-0.4	-0.2	0.0	-0.8	-0.7	-0.4	1.6	-0.4	1.1	-0.6
Myopia	0.8	1.1	4.8	-1.7	2.2	1.1	1.1	1.0	1.1	1.0	1.0	-0.0	1.1	0.9	0.6	0.1	0.3	-0.8	-0.5	1.0
Vascular/heart problems diagnosed by doctor	0.8	2.2	4.9	-0.3	-0.9	2.1	0.4	2.2	2.0	2.2	1.7	1.6	1.4	1.9	1.3	0.7	0.6	0.9	0.7	1.7
Cholesterol lowering medication	0.5	0.8	3.2	-1.1	0.5	0.3	1.0	0.8	-1.3	0.4	0.7	0.6	-0.3	0.9	0.5	-1.8	-0.1	-1.3	-0.4	1.0
Medication: Omeprazole (e.g. Zanprol)	1.9	2.3	5.2	-1.6	0.5	2.1	1.6	1.9	-0.7	1.9	1.6	2.3	-0.3	1.9	1.1	-1.0	-0.0	0.1	2.2	1.6
Pain experienced in last month	3.7	6.2	12.0	2.5	-2.8	-3.4	-3.1	-3.5	-2.0	-3.1	-3.0	-2.6	-2.0	-3.0	-1.7	-1.0	-0.7	0.2	-1.5	-3.1
Supplements: Calcium	0.5	0.5	4.2	-0.6	1.0	-0.0	0.3	-0.3	-2.0	0.3	-0.4	0.2	0.4	-0.0	0.6	1.5	-0.0	0.7	0.2	-0.4
Basal cell carcinoma (self-reported)	0.6	0.7	5.6	-0.6	-1.0	-0.3	0.6	0.2	-0.4	-0.8	0.3	-0.3	-2.4	-0.2	-0.2	0.2	-1.1	1.4	-1.0	0.0
Heart attack/myocardial infarction (self-reported)	1.9	2.4	5.0	-1.5	1.8	1.9	1.3	2.2	1.8	1.9	1.5	1.1	-0.2	1.6	1.2	-1.4	1.4	-0.1	1.9	1.9
Deep venous thrombosis (DVT) (self-reported)	0.8	1.0	4.6	0.6	0.6	-0.5	-0.9	-0.6	2.1	-0.4	-1.0	-0.9	-0.6	-0.9	-0.6	-1.0	-2.1	-0.5	-1.0	-0.4
Heart disease (siblings)	0.9	1.1	6.3	-0.8	-1.5	1.1	-0.2	0.8	-0.8	1.3	0.6	1.0	1.5	0.7	0.1	0.3	-2.5	-0.5	0.8	0.4
Alcohol drinker status: Previous	0.7	0.8	3.1	0.9	-0.9	0.1	0.1	0.1	0.9	-0.4	0.7	-0.4	-1.2	0.3	-0.4	-1.7	1.8	-1.0	1.1	1.0
Pack years of smoking	0.6	0.9	2.7	0.5	-0.3	0.8	1.6	1.3	0.7	0.3	1.6	0.1	-0.8	0.9	-0.1	-0.8	1.0	-0.8	0.6	1.7
Impedance of whole body	0.7	3.6	8.7	-1.3	-1.3	2.5	1.1	1.9	-0.4	2.8	1.7	1.8	1.5	2.3	3.0	1.5	2.2	1.4	2.2	1.7
Leg fat mass (left)	0.8	3.0	8.2	2.3	0.9	-2.1	-1.0	-1.6	0.7	-2.5	-1.0	-1.2	-1.4	-2.0	-2.9	-1.0	-2.2	-1.0	-2.4	-1.2
Arm predicted mass (left)	0.5	2.7	9.7	0.1	2.8	-1.4	-0.8	-0.8	3.1	-1.9	-0.3	-0.2	-1.0	-1.3	-2.2	-2.9	-1.9	-1.2	-0.6	-0.4