Hub : Genes

NIPSNAP1

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.1600 0.0400 5.5e-13 0.146 0.106 0.123 0.086 0.110 2.1e-17 8.2e-13 8.7e-15 1.2e-10 2.4e-13
2 GTEx Adipose Subcutaneous 0.0710 0.0320 3.7e-03 0.058 NA 0.055 NA 0.039 1.5e-05 NA 2.5e-05 NA 3.6e-04
3 GTEx Adrenal Gland 0.1392 0.0567 1.6e-03 0.162 NA 0.119 NA 0.113 1.9e-06 NA 4.7e-05 NA 7.7e-05
4 GTEx Artery Aorta 0.1590 0.0530 1.0e-04 0.092 NA 0.072 NA 0.032 9.5e-06 NA 8.9e-05 NA 6.9e-03
5 GTEx Artery Coronary 0.2640 0.0780 4.5e-06 0.234 NA 0.205 NA 0.245 1.9e-08 NA 1.8e-07 NA 8.7e-09
6 GTEx Artery Tibial 0.2014 0.0487 2.5e-10 0.157 NA 0.172 NA 0.106 2.6e-12 NA 1.9e-13 NA 1.2e-08
7 GTEx Brain Nucleus accumbens basal ganglia 0.2010 0.0910 7.1e-03 -0.004 NA -0.009 NA -0.011 4.3e-01 NA 6.7e-01 NA 8.2e-01
8 GTEx Cells EBV-transformed lymphocytes 0.3770 0.0880 1.8e-06 0.182 NA 0.261 NA 0.227 1.4e-06 NA 4.4e-09 NA 5.7e-08
9 GTEx Cells Transformed fibroblasts 0.1170 0.0320 3.8e-09 0.166 NA 0.134 NA 0.056 1.8e-12 NA 3.1e-10 NA 4.7e-05
10 GTEx Colon Sigmoid 0.2170 0.0930 1.1e-03 0.154 NA 0.097 NA 0.117 4.2e-06 NA 2.6e-04 NA 6.2e-05
11 GTEx Esophagus Mucosa 0.1890 0.0510 4.3e-07 0.040 NA 0.100 NA 0.057 1.0e-03 NA 3.3e-07 NA 1.1e-04
12 GTEx Esophagus Muscularis 0.1510 0.0510 1.1e-05 0.161 NA 0.115 NA 0.095 4.9e-10 NA 1.9e-07 NA 2.3e-06
13 GTEx Heart Atrial Appendage 0.1400 0.0560 1.8e-03 0.147 NA 0.103 NA 0.011 4.1e-07 NA 2.3e-05 NA 1.0e-01
14 GTEx Heart Left Ventricle 0.0900 0.0409 2.6e-03 0.061 NA 0.030 NA 0.011 3.5e-04 NA 9.7e-03 NA 8.2e-02
15 GTEx Lung 0.2296 0.0588 9.8e-07 0.000 NA 0.074 NA 0.020 3.0e-01 NA 2.5e-06 NA 1.1e-02
16 GTEx Nerve Tibial 0.1228 0.0453 2.4e-04 0.102 NA 0.059 NA 0.069 1.2e-07 NA 5.1e-05 NA 1.3e-05
17 GTEx Pancreas 0.1120 0.0510 5.8e-03 0.064 NA 0.063 NA 0.054 1.2e-03 NA 1.2e-03 NA 2.6e-03
18 GTEx Skin Sun Exposed Lower leg 0.0720 0.0310 2.8e-03 0.055 NA 0.029 NA 0.034 2.2e-05 NA 1.9e-03 NA 7.8e-04
19 GTEx Testis 0.1400 0.0460 8.2e-05 0.212 NA 0.179 NA 0.192 9.2e-10 NA 2.3e-08 NA 6.2e-09
20 GTEx Thyroid 0.0970 0.0310 2.6e-06 0.070 NA 0.091 NA -0.004 4.7e-06 NA 1.9e-07 NA 9.9e-01
21 GTEx Whole Blood 0.0540 0.0240 9.6e-03 0.002 NA 0.006 NA 0.000 2.1e-01 NA 8.8e-02 NA 3.0e-01
22 METSIM Adipose 0.0216 0.0118 1.3e-02 0.012 0.013 0.017 0.015 0.013 4.8e-03 3.5e-03 1.0e-03 1.9e-03 3.6e-03
23 YFS Blood 0.0820 0.0211 1.4e-12 0.013 0.047 0.049 0.054 0.040 3.7e-05 3.3e-15 1.4e-15 2.9e-17 3.2e-13
24 TCGA Bladder Urothelial Carcinoma 0.0410 0.0280 2.2e-03 0.020 0.026 0.019 NA 0.023 7.4e-03 2.7e-03 8.2e-03 NA 4.5e-03
25 TCGA Breast Invasive Carcinoma 0.0431 0.0189 6.4e-12 0.064 0.061 0.054 NA 0.063 3.8e-13 1.7e-12 3.8e-11 NA 8.4e-13
26 TCGA Colon Adenocarcinoma 0.2300 0.1390 5.2e-05 0.078 0.074 0.080 NA 0.069 2.9e-05 4.5e-05 2.3e-05 NA 8.3e-05
27 TCGA Head and Neck Squamous Cell Carcinoma 0.0320 0.0253 4.1e-03 0.022 0.014 0.009 NA 0.016 1.5e-03 8.2e-03 3.2e-02 NA 5.1e-03
28 TCGA Brain Lower Grade Glioma 0.0890 0.0560 8.2e-06 0.046 0.038 0.028 NA 0.040 5.6e-06 3.6e-05 3.0e-04 NA 2.3e-05
29 TCGA Liver Hepatocellular Carcinoma 0.0590 0.0380 5.6e-03 0.046 0.057 0.060 NA 0.010 3.2e-03 1.1e-03 8.6e-04 NA 1.0e-01
30 TCGA Lung Adenocarcinoma 0.0675 0.0343 6.6e-08 0.068 0.059 0.069 NA 0.068 2.1e-08 1.7e-07 1.6e-08 NA 2.1e-08
31 TCGA Lung Squamous Cell Carcinoma 0.0522 0.0250 2.4e-07 0.066 0.066 0.056 NA 0.064 5.2e-08 5.7e-08 6.0e-07 NA 9.5e-08
32 TCGA Prostate Adenocarcinoma 0.0498 0.0276 3.4e-05 0.046 0.048 0.040 NA 0.043 1.2e-05 8.3e-06 4.6e-05 NA 2.2e-05
33 TCGA Soft Tissue Sarcoma 0.1060 0.0740 3.9e-04 0.061 0.012 0.012 NA -0.005 1.6e-04 6.3e-02 6.0e-02 NA 8.4e-01
34 TCGA Stomach Adenocarcinoma 0.0510 0.0320 1.2e-03 0.036 0.033 0.029 NA 0.006 1.3e-03 2.0e-03 3.4e-03 NA 1.2e-01
35 TCGA Testicular Germ Cell Tumors 0.1980 0.1010 8.3e-05 0.110 0.095 0.092 NA -0.008 1.0e-04 3.2e-04 3.9e-04 NA 9.2e-01
36 TCGA Thyroid Carcinoma 0.1360 0.0470 0.0e+00 0.155 0.178 0.173 NA 0.105 6.3e-15 4.6e-17 1.4e-16 NA 2.2e-10

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36
Bipolar Disorder (2018) 1.0 1.6 3.6 -1.3 -0.4 -1.1 -1.7 -1.3 -0.3 -1.4 -0.5 -0.9 -1.4 -0.4 -1.5 -1.1 -1.0 -0.6 -1.3 -1.8 -1.9 1.6 -1.9 -1.4 -0.5 -1.6 -1.4 -1.4 -1.4 -1.0 -1.1 -1.8 -0.7 -1.2 -1.6 -1.0 -1.2 -1.1 -0.8
Bipolar Disorder or Schizophrenia 3.3 8.0 12.5 -2.8 -2.5 -2.4 -3.5 -3.0 -2.0 -3.0 -2.3 -2.7 -3.5 -2.3 -3.0 -2.9 -2.8 -2.8 -2.9 -3.2 -2.2 3.1 -3.3 -2.8 -2.3 -2.7 -2.9 -2.9 -2.7 -3.0 -2.9 -3.1 -2.7 -2.9 -3.1 -3.1 -2.9 -2.8 -2.6
Depressed Affect (Nagel 2018) 4.6 9.7 21.2 3.5 3.2 3.5 3.8 3.5 2.2 4.6 1.4 3.4 3.0 2.7 3.6 3.5 3.3 1.6 3.4 3.0 1.9 -3.7 3.5 1.1 3.9 1.3 2.7 3.6 2.2 3.6 3.4 3.0 3.7 3.3 2.8 2.5 3.4 2.8 2.9
Depression (Nagel 2018) 0.6 0.9 2.6 1.2 0.0 0.7 1.0 0.8 -0.2 1.6 1.1 0.9 -0.3 1.2 0.9 0.8 0.9 -0.9 0.8 1.1 0.8 -1.0 1.3 -0.0 1.0 1.2 1.0 1.0 1.2 0.7 0.7 1.1 1.0 0.9 1.1 0.5 0.9 1.0 0.6
Intelligence (Savage-Jansen 2018) 0.1 0.2 2.7 0.1 0.3 0.1 0.1 0.3 0.4 -0.0 -0.1 0.4 0.3 -0.3 0.4 0.2 0.2 0.8 0.4 0.3 0.1 -0.4 -0.2 1.7 -0.6 0.1 0.5 0.5 0.4 0.0 0.1 0.6 0.1 0.2 0.5 -0.1 0.4 0.3 -0.2
Neuroticism (Nagel 2018) 2.6 6.1 13.5 2.8 2.0 2.3 2.9 2.6 0.6 3.7 1.8 2.6 1.5 2.2 2.8 2.5 2.5 0.3 2.8 2.3 2.5 -3.2 3.4 1.0 2.9 2.1 2.5 2.8 2.2 2.5 2.6 2.7 2.6 2.6 2.6 1.7 2.8 2.4 1.9
Schizophrenia (2018) 3.4 7.1 10.8 -2.5 -3.0 -2.2 -3.2 -2.8 -2.4 -2.7 -2.6 -2.7 -3.3 -2.6 -2.7 -2.9 -2.8 -3.0 -2.7 -2.7 -1.4 2.6 -2.7 -2.4 -2.5 -2.2 -2.6 -2.7 -2.3 -3.0 -2.8 -2.5 -2.7 -2.8 -2.7 -2.6 -2.8 -2.8 -2.7
Schizophrenia vs Biploar Disorder 0.2 0.2 1.7 0.7 -0.7 0.5 0.6 0.1 0.1 -0.4 0.3 -0.0 0.6 -0.5 0.2 0.1 -0.1 0.4 0.1 0.8 1.3 -0.3 0.0 0.3 0.4 0.9 0.1 -0.0 -0.5 -0.0 0.1 0.5 -0.5 -0.0 0.4 -0.2 -0.1 0.0 0.0
Worry (Nagel 2018) 1.7 3.5 11.1 2.5 0.9 0.2 1.8 1.8 -0.3 2.3 1.8 2.0 0.1 1.5 2.0 1.7 2.0 -0.4 2.1 1.8 3.3 -2.5 2.2 0.7 1.8 2.0 2.7 2.1 1.5 1.3 1.8 2.8 1.3 1.6 2.6 1.9 1.9 2.3 0.7
Alzheimer’s Disease (in mother) 0.8 1.0 4.4 -0.8 -0.3 -0.9 -0.6 -0.7 -1.0 -0.6 -1.5 -0.7 -0.8 -1.4 -0.6 -1.0 -0.5 -0.9 -0.7 -1.4 0.0 0.5 -0.3 0.0 -1.1 -2.1 -0.8 -0.7 -1.5 -0.6 -0.6 -0.6 -1.0 -1.1 -1.0 -1.9 -0.8 -1.2 -1.3
Alzheimer’s Disease (in father) 0.2 0.2 2.2 -0.1 -1.2 -0.2 -0.3 0.0 -0.6 -0.1 -0.1 0.0 -0.2 0.5 0.1 -0.2 -0.1 1.2 0.2 -0.7 -0.2 -0.1 0.1 0.2 -1.0 -0.5 -0.1 0.1 0.3 -0.3 0.0 0.2 0.2 -0.3 -0.1 -1.5 0.1 -0.3 -0.8
Alzheimer’s Disease (including proxy) 1.0 1.4 6.6 -1.1 -1.2 -1.9 -1.1 -0.9 -1.6 -1.2 -1.0 -0.8 -0.8 -1.2 -0.8 -1.2 -0.7 -0.0 -0.8 -2.0 0.4 0.6 -0.7 -0.0 -1.7 -1.8 -0.6 -0.9 -1.2 -0.9 -0.8 -0.4 -1.1 -1.4 -0.8 -2.6 -1.0 -1.1 -1.9
Crohns Disease (2017) 0.6 1.3 8.6 -0.4 -0.8 1.3 -0.5 -0.8 0.4 -1.6 -0.8 -1.0 -1.1 -0.1 -1.0 -0.6 -0.5 -0.5 -1.2 -0.9 -2.2 1.1 -0.9 -2.9 0.7 -0.9 -2.0 -1.1 -0.9 -0.9 -0.8 -2.0 -0.7 -0.2 -1.8 -0.3 -0.8 -1.1 0.8
Irritable Bowel Disease (IBD) 0.9 2.1 10.6 -0.6 -1.7 0.6 -0.4 -1.3 0.6 -2.5 -1.1 -1.7 -1.4 -1.2 -1.4 -0.9 -0.9 -0.7 -1.7 -1.5 -1.8 1.4 -1.4 -3.3 0.6 -1.5 -2.0 -1.6 -1.3 -1.5 -1.2 -2.1 -1.9 -0.6 -2.0 -0.6 -1.5 -0.9 0.6
Ulcerative Colitis (UC) 1.5 2.8 7.9 -1.1 -2.6 -0.7 -0.9 -1.7 -0.3 -2.7 -0.8 -2.1 -1.5 -2.0 -1.8 -1.4 -1.4 -0.6 -1.9 -1.7 -0.7 1.8 -1.8 -2.5 -0.2 -1.6 -1.6 -1.9 -1.3 -2.1 -1.7 -1.9 -2.8 -1.3 -1.8 -0.9 -2.1 -1.0 -0.5
Major Depression (MDD) 0.4 0.5 4.4 -0.0 0.1 1.6 0.1 0.2 0.3 0.9 -0.3 0.3 0.1 1.0 0.4 0.0 0.4 0.1 0.2 0.3 -0.8 -0.6 1.0 -2.1 0.3 -1.0 -0.6 0.4 0.8 0.4 0.2 -0.3 1.1 0.2 -0.4 1.1 0.5 -0.6 -0.2
Reaction Time 0.5 0.9 3.5 -1.0 -0.6 -1.2 -1.3 -0.9 -1.7 -0.7 1.9 -0.6 -1.6 0.6 -1.0 -1.1 -1.2 -0.1 -0.7 -0.3 -0.1 1.0 -0.3 -1.4 -0.5 0.9 -0.6 -0.9 -0.1 -0.8 -0.6 -0.5 -0.4 -1.3 -0.4 -0.8 -0.7 -0.9 -1.3
Verbal and Numeric Reasoning (VNR) 0.1 0.2 0.8 -0.0 0.3 0.7 0.1 0.5 0.4 0.4 0.3 0.6 0.9 -0.2 0.5 0.4 0.5 0.5 0.5 0.5 -0.3 -0.3 0.4 0.6 0.4 -0.7 0.1 0.5 -0.0 0.2 0.4 0.2 0.4 0.5 0.1 0.2 0.4 0.1 0.5
Breast Cancer 0.2 0.6 3.8 -0.6 0.9 -0.2 -1.5 -0.5 0.1 -1.2 -0.7 -0.6 -0.7 0.5 -0.5 -0.5 -0.4 0.8 -0.9 -0.8 -1.2 0.7 0.2 1.4 -0.6 -0.1 -0.9 -0.4 0.2 -0.7 -0.5 -0.5 -0.4 -0.3 -0.5 -1.9 -0.3 -0.7 -0.1
Ovarian Cancer 0.6 0.8 3.9 -0.9 -0.7 -0.8 -0.9 -0.9 -0.3 -0.6 -2.0 -0.8 -1.7 -0.8 -0.7 -0.9 -0.8 -0.3 -0.7 -1.1 -0.9 0.6 -0.7 -0.3 -1.5 -1.2 -0.6 -0.6 -0.6 -1.1 -0.8 -0.5 -0.8 -0.9 -0.8 -0.1 -0.8 -0.6 -1.1
Prostate Cancer 2.3 3.2 7.8 -1.7 -2.4 -1.4 -1.6 -2.1 -1.7 -2.8 -1.5 -2.2 -2.0 -1.3 -2.2 -1.9 -2.0 -0.8 -2.4 -1.0 -1.0 2.3 -1.8 -1.5 -0.8 -0.0 -1.6 -2.1 -1.3 -1.9 -2.1 -1.9 -2.0 -1.9 -1.7 -1.3 -2.2 -1.3 -1.5
Age at First Birth 2.1 3.1 7.3 -1.2 -2.7 -2.5 -1.6 -1.5 -1.4 -1.9 -1.8 -2.0 -1.9 -1.9 -1.6 -1.5 -1.5 -1.6 -1.7 -2.6 -1.0 1.6 -1.7 -0.6 -2.2 -2.4 -1.3 -1.6 -1.9 -1.8 -1.6 -1.4 -1.8 -1.7 -1.7 -1.6 -1.8 -1.5 -1.6
Bipolar Disorder (2011) 0.5 0.4 2.0 -0.8 -0.5 -0.4 -0.8 -0.7 -0.1 -1.4 -0.4 -0.7 -0.4 0.0 -0.8 -0.6 -0.8 0.2 -0.6 -0.3 -1.0 0.8 -1.2 -0.7 -1.0 -0.1 -0.7 -0.7 0.2 -0.3 -0.7 -0.9 -0.4 -0.7 -0.7 -0.2 -0.6 -0.5 -0.4
Body Mass Index (BMI) (2010) 2.7 3.6 6.7 -2.2 -2.2 -1.2 -1.9 -2.1 -2.6 -1.7 -0.1 -2.1 -1.8 -0.9 -2.0 -2.1 -2.1 -1.2 -2.0 -1.9 -0.9 2.1 -1.3 -2.3 -1.7 -1.6 -2.5 -2.1 -1.2 -1.9 -2.0 -2.1 -1.7 -2.1 -2.1 -2.4 -2.0 -2.5 -1.8
Coronary Artery Disease (CAD) 0.5 0.5 5.3 0.5 -0.0 1.3 0.6 0.4 1.1 0.6 -0.1 0.5 -0.3 0.4 0.6 0.5 0.5 -0.4 0.4 -0.1 -2.3 -0.5 0.2 0.9 0.9 -0.2 -0.3 0.6 0.7 -0.1 0.3 -0.4 0.8 1.1 -0.4 0.8 0.5 0.3 1.4
Crohns Disease (2012) 0.3 0.4 2.4 0.1 -0.1 1.4 0.3 0.0 1.0 -1.5 -0.5 -0.4 0.4 0.3 -0.4 0.2 -0.1 0.5 -0.5 0.3 -1.2 0.6 -0.5 -1.5 0.5 0.2 -0.8 -0.4 -0.8 0.3 -0.0 -0.9 0.3 0.2 -0.7 -0.2 -0.2 -0.2 1.0
Mean Putamen Volume 0.5 0.6 2.5 -1.0 0.0 0.1 -1.1 -0.6 -0.3 -0.3 -0.5 -0.7 -0.5 -0.9 -0.6 -0.7 -0.5 -0.6 -0.4 -0.9 -0.4 0.6 -0.4 1.4 -1.0 -1.1 -0.7 -0.5 -1.6 -0.5 -0.4 -0.7 -0.2 -0.7 -0.9 -1.1 -0.5 -1.0 -0.9
Fasting Glucose 2.1 2.5 4.2 -1.8 -1.0 -1.7 -1.5 -1.5 -1.1 -1.7 -1.0 -1.8 -1.9 -1.4 -1.6 -1.6 -1.7 -1.8 -1.4 -1.9 -1.9 1.7 -2.0 0.2 -1.2 -1.7 -1.6 -1.6 -2.0 -1.6 -1.4 -1.7 -1.5 -1.7 -1.8 -0.8 -1.7 -1.7 -1.6
HbA1C 1.1 1.2 3.9 0.9 0.8 1.5 1.0 1.1 1.1 1.5 1.9 0.8 0.6 1.4 0.9 1.1 1.3 1.1 1.0 0.8 -0.5 -0.9 2.0 0.3 1.7 0.9 0.4 0.9 0.9 0.7 0.9 0.4 1.4 1.3 0.5 1.1 1.1 0.6 1.6
HDL Cholesterol 0.9 1.5 5.7 -1.5 -0.8 -1.6 -1.0 -0.9 -0.3 -2.1 -2.4 -1.2 -0.4 -1.3 -1.1 -1.0 -1.1 0.5 -1.4 -1.8 -1.1 1.1 -1.9 -0.7 -1.3 -1.4 -0.8 -1.1 -1.4 -0.9 -1.0 -0.9 -1.2 -1.2 -1.0 -1.6 -1.1 -0.6 -1.2
LDL Cholesterol 0.2 0.3 2.8 0.4 0.2 -0.3 -0.0 0.0 -0.6 -0.1 -0.1 0.1 0.1 0.3 0.1 0.1 0.1 -0.2 -0.1 0.3 1.7 -0.1 1.0 0.0 1.2 0.5 0.7 0.2 -0.3 0.5 0.4 0.7 0.0 0.1 0.6 -0.4 0.0 0.8 0.0
Lupus 0.8 1.2 2.7 1.6 0.7 0.5 0.8 1.4 1.1 1.1 0.9 1.6 1.3 1.3 1.2 1.4 1.4 0.5 1.5 0.6 0.7 -0.4 0.5 1.6 0.8 -0.6 1.3 1.3 0.1 1.1 1.5 0.8 0.5 1.1 1.0 1.3 1.2 1.2 1.3
Neuroticism (2016) 1.8 2.6 6.4 1.6 0.9 1.8 1.7 1.5 0.9 2.2 1.3 1.6 0.7 1.2 1.7 1.5 1.5 0.0 1.8 1.8 1.2 -2.1 2.2 0.2 1.0 1.0 1.7 1.7 2.5 1.5 1.7 1.8 1.7 1.7 1.7 2.4 1.7 1.6 1.4
Primary Biliary Cirrhosis 0.9 1.3 4.9 1.1 0.9 2.2 1.8 1.4 1.0 1.6 1.1 1.3 0.9 1.5 1.2 1.3 1.2 -0.6 1.3 1.1 -0.9 -0.9 0.5 0.1 -0.4 0.8 0.1 1.2 0.4 1.2 1.4 0.4 1.6 1.6 0.3 0.3 1.3 0.4 1.9
Rheumatoid Arthritis 1.2 1.6 4.4 1.0 1.7 1.9 1.2 1.2 1.9 1.2 0.7 1.1 1.1 1.6 1.2 1.1 1.1 1.0 1.4 1.0 -0.7 -1.1 1.3 1.9 0.1 1.0 0.6 1.3 1.5 1.5 1.4 0.6 2.1 1.0 0.8 1.9 1.5 0.6 1.0
Schizophrenia (2014) 1.8 3.9 5.6 -1.7 -1.9 -2.1 -2.3 -2.0 -1.7 -2.2 -2.2 -2.0 -2.0 -2.4 -2.0 -2.1 -2.1 -2.1 -1.9 -2.1 -1.0 1.7 -2.0 -2.3 -1.9 -2.2 -1.8 -1.9 -1.8 -1.7 -2.0 -1.8 -1.9 -2.2 -1.9 -1.3 -2.0 -2.1 -2.3
Triglycerides 1.1 1.7 4.1 1.4 0.7 1.4 1.3 1.1 0.9 1.7 1.6 1.3 0.6 0.8 1.3 1.3 1.5 0.0 1.4 2.0 1.7 -1.4 1.6 0.9 1.9 1.2 1.5 1.3 1.0 0.8 1.1 1.5 0.9 1.5 1.4 1.4 1.2 1.5 1.3
Type 2 Diabetes (T2D) (2012) 1.5 1.8 7.9 -1.6 -0.8 0.5 -1.1 -1.4 0.3 0.4 -1.6 -1.4 -1.1 -1.2 -1.4 -1.2 -1.3 -1.9 -1.1 -0.9 -2.8 1.5 -0.2 -0.6 0.3 -1.7 -2.0 -1.4 -0.8 -1.4 -1.5 -2.1 -0.6 -0.7 -2.2 -0.1 -1.2 -1.6 -0.2
Ulcerative Colitis 0.9 1.3 3.6 -0.6 -1.8 -0.1 -0.4 -1.1 0.4 -1.9 -0.7 -1.4 -1.3 -1.1 -1.2 -0.8 -1.0 -0.2 -1.3 -0.9 -1.2 1.0 -1.3 -1.7 -0.2 -1.2 -1.3 -1.3 -1.1 -1.4 -1.2 -1.4 -1.4 -0.6 -1.4 -0.3 -1.3 -0.5 0.1
Blood Eosinophil Count 0.3 2.0 5.9 -1.3 -1.8 -2.4 -1.2 -1.0 -2.0 -2.0 -2.4 -1.2 -1.6 -0.8 -0.8 -1.3 -1.3 0.1 -1.0 -1.9 0.7 0.4 -1.6 -1.7 -1.9 -0.6 -0.1 -0.8 -1.1 -1.3 -0.8 0.4 -1.7 -1.6 -0.1 -2.4 -1.0 -0.8 -2.4
Blood Platelet Count 1.4 16.1 52.6 -4.1 -4.4 -7.2 -5.8 -3.7 -6.4 -4.5 -3.0 -4.1 -4.8 -3.3 -3.6 -4.1 -3.5 -2.5 -3.5 -5.3 1.2 3.3 -1.7 -1.0 -2.9 -4.3 -1.9 -3.4 -2.9 -3.6 -3.3 -1.6 -4.3 -5.1 -2.0 -5.3 -3.9 -3.3 -6.2
Blood Red Count 0.1 0.9 7.9 0.6 0.2 0.1 0.0 -0.2 -0.6 1.9 1.2 0.3 0.3 0.7 0.6 -0.0 0.3 -2.2 0.8 0.4 0.9 -0.7 1.4 -2.8 1.6 -0.2 0.4 0.8 1.0 0.8 -0.1 -0.0 0.8 0.2 0.2 1.0 0.3 -0.0 -0.0
Blood White Count 2.6 19.1 32.7 -5.2 -4.7 -4.0 -4.4 -4.8 -4.1 -5.2 -3.8 -5.4 -4.3 -4.0 -5.0 -4.8 -5.0 -3.0 -5.0 -4.6 -2.8 4.2 -2.5 -5.7 -1.9 -3.7 -4.2 -4.9 -4.0 -3.9 -4.6 -4.1 -4.4 -4.8 -4.3 -3.4 -4.9 -4.3 -4.6
Heel T-Score 0.5 3.7 32.5 0.0 0.4 -2.2 0.6 0.3 -3.4 0.3 3.8 1.1 1.3 0.9 0.3 0.2 1.4 0.7 0.2 1.3 5.1 0.1 -1.9 -5.7 3.6 2.4 1.3 0.2 0.7 0.9 0.6 1.8 -0.2 -0.5 1.9 -1.1 0.1 0.8 -0.4
BMI 0.5 2.8 6.0 -2.0 -2.0 0.1 -1.6 -1.8 -0.8 -1.1 -1.5 -1.7 -1.6 -0.6 -1.6 -1.7 -1.8 -0.9 -1.6 -1.8 -2.5 1.9 -2.0 -1.0 -1.1 -2.2 -2.2 -1.5 -1.6 -1.9 -1.9 -2.3 -1.1 -1.4 -2.4 -1.3 -1.5 -2.0 -1.0
Height 0.6 12.5 28.6 -4.5 -3.2 -3.5 -2.5 -3.6 -2.9 -5.2 -3.9 -3.8 -2.0 -5.1 -3.4 -3.6 -3.2 0.1 -3.7 -4.3 -0.5 2.3 -5.3 -4.7 -4.3 -3.5 -3.1 -3.7 -2.7 -3.3 -3.7 -2.8 -3.9 -3.5 -3.1 -1.9 -3.5 -3.1 -3.7
Waist Hip Ratio (WHR) 1.3 5.9 23.1 3.4 1.4 4.8 1.8 2.4 3.5 3.3 1.7 2.3 1.4 3.8 2.5 2.4 2.3 1.4 2.4 1.4 -1.6 -2.3 3.9 -0.9 3.2 0.9 0.8 2.6 1.4 1.8 2.1 1.2 3.2 3.1 0.9 0.7 2.7 1.5 3.1
Systolic Blood Pressure 0.3 1.5 9.0 1.8 -0.9 3.0 1.0 0.7 2.3 2.1 -0.2 0.8 -0.1 1.7 0.9 0.7 0.6 -0.1 0.7 0.5 -1.8 -1.0 1.9 -0.7 1.2 -0.1 -0.1 0.9 0.1 0.1 0.6 -0.2 1.7 1.6 -0.4 1.4 1.1 0.3 1.6
Smoking Status 0.1 0.1 1.6 -0.3 -0.0 0.8 0.1 -0.4 0.1 0.2 0.3 0.0 -0.2 -0.4 -0.3 -0.3 -0.1 0.1 -0.4 -0.1 -0.2 0.3 -0.3 -1.3 0.3 0.1 -0.2 -0.3 -0.3 -0.5 -0.6 -0.5 -0.3 0.2 -0.4 0.2 -0.2 0.3 0.4
Allergy or Eczema 1.0 2.7 7.6 -1.7 -1.7 -2.7 -1.6 -1.5 -2.7 -2.3 -0.8 -1.7 -1.3 -0.7 -1.4 -1.7 -1.3 -0.2 -1.5 -2.2 0.4 1.1 -0.5 -2.3 -1.9 -1.0 -1.2 -1.5 -1.3 -1.2 -1.3 -0.7 -1.6 -2.0 -0.9 -2.8 -1.5 -1.6 -2.2
Cardiovascular Disease 2.5 8.3 19.6 4.0 1.5 4.4 3.3 3.0 3.6 3.1 1.9 3.1 2.7 3.0 3.1 3.2 3.0 1.5 2.9 3.4 1.2 -2.8 3.0 2.1 2.9 1.9 2.4 3.0 1.3 2.3 2.7 2.4 2.8 3.7 2.2 2.4 3.0 3.0 3.9
Hypothyroidism (self reported) 4.3 9.8 20.4 2.5 4.1 3.4 2.4 3.3 2.4 4.5 3.4 3.5 3.1 3.3 3.5 3.1 3.6 1.6 3.6 3.0 2.0 -3.2 4.0 2.2 2.3 2.1 2.7 3.6 3.2 3.4 3.5 2.9 4.3 2.9 2.9 2.4 3.5 2.3 2.3
Respiratory disease 0.6 1.3 5.6 -0.8 -0.5 -1.8 -1.0 -0.8 -1.5 -0.6 -1.6 -1.0 -1.0 -2.4 -0.7 -0.8 -0.6 -1.8 -0.6 -1.3 1.7 0.4 -0.7 0.7 0.3 -2.3 -0.0 -0.6 -1.0 -0.5 -0.8 -0.1 -1.5 -1.2 -0.3 -1.2 -1.0 -0.5 -1.5
Type 2 Diabetes (T2D) (2018) 0.8 1.5 4.4 -1.3 -1.1 0.7 -0.8 -1.5 0.9 -1.0 -1.0 -1.4 -1.3 -0.9 -1.4 -1.2 -1.0 -0.1 -1.7 -0.8 -1.4 1.6 -0.6 0.3 0.1 -1.0 -1.4 -1.4 -1.9 -2.1 -1.6 -1.7 -1.8 -0.7 -1.8 -0.8 -1.5 -0.8 -0.1
Lung FEV1/FVC ratio 9.5 48.1 78.9 8.0 6.4 4.0 7.6 7.8 5.2 6.5 5.8 8.9 8.1 6.4 7.7 7.7 8.0 7.1 7.6 6.8 7.0 -7.1 5.0 1.9 8.2 4.8 7.7 7.6 4.6 7.4 7.7 7.4 6.5 7.0 7.7 6.0 7.4 7.5 6.5
Lung FVC 1.3 6.8 21.9 -2.2 -2.4 -4.7 -2.3 -2.2 -3.3 -4.3 -3.0 -2.3 -1.5 -3.2 -2.4 -2.3 -2.3 -0.4 -2.4 -3.5 0.3 2.3 -4.3 -1.9 -2.0 -3.2 -1.3 -2.4 -2.4 -1.7 -2.1 -1.5 -3.2 -3.0 -1.4 -2.3 -2.4 -1.8 -3.1
Neuroticism 2.4 5.8 11.6 2.8 2.0 2.1 2.5 2.7 0.5 3.4 1.9 2.8 1.3 2.4 2.7 2.4 2.5 -0.4 2.8 2.4 2.6 -3.1 3.0 1.2 1.9 2.1 2.8 2.7 2.0 2.5 2.6 2.9 2.6 2.5 2.7 1.8 2.7 2.3 1.6
Chronotype (morning person) 0.8 1.8 5.3 1.7 2.2 0.8 1.1 1.5 0.7 2.2 1.1 1.5 0.6 1.3 1.2 1.5 1.1 -0.0 1.4 1.1 0.8 -1.1 1.1 2.3 1.3 1.0 1.6 1.3 1.2 1.5 1.7 1.2 1.5 1.3 1.3 0.4 1.4 1.5 1.2
Hair Pigment 0.0 0.8 5.3 1.2 -0.7 1.5 -0.0 0.6 -0.0 0.6 -0.3 0.7 -0.5 2.3 0.5 0.5 0.3 0.5 0.8 0.3 -1.1 -0.4 1.7 -0.6 1.2 1.3 0.1 0.7 0.8 0.4 0.7 0.1 1.6 0.7 0.3 0.8 1.1 0.3 0.5
Tanning 0.9 11.5 16.2 -3.2 -2.9 -4.0 -3.6 -3.8 -4.0 -3.3 -3.0 -3.4 -3.8 -3.4 -3.7 -3.8 -3.4 -3.1 -3.8 -3.7 -0.6 3.6 -3.5 -1.6 -2.9 -2.4 -2.7 -3.6 -3.1 -3.6 -3.7 -2.9 -3.9 -3.8 -3.0 -3.9 -3.7 -3.0 -3.9
Hand grip strength (left) 0.8 2.0 8.0 -1.1 -2.0 -2.0 -1.0 -1.1 -1.4 -2.4 -1.9 -1.5 -1.0 -2.4 -1.3 -1.1 -0.8 -0.9 -1.3 -1.7 0.8 1.3 -2.8 -0.3 -1.0 -1.5 -0.5 -1.2 -1.1 -1.4 -1.2 -0.7 -2.2 -1.5 -0.7 -1.0 -1.4 -0.6 -1.4
Number of treatments/medications taken 1.7 3.0 5.9 2.4 1.1 2.4 1.9 1.9 1.7 2.1 0.5 1.9 0.9 1.8 2.3 1.9 2.2 0.2 2.2 1.5 0.7 -2.1 1.7 1.8 0.6 0.4 1.5 2.3 1.0 1.7 1.9 1.7 2.2 2.1 1.5 1.1 2.2 1.4 1.8
Average weekly spirits intake 0.4 0.5 4.3 -0.7 -0.3 1.0 -0.6 -0.5 -0.1 -0.2 0.8 -0.6 -0.5 0.4 -0.7 -0.5 -0.8 -0.1 -0.6 0.5 -2.1 0.9 0.7 -0.2 1.2 0.7 -1.2 -0.7 -0.1 -0.2 -0.6 -1.1 0.1 -0.2 -0.9 -0.5 -0.5 -0.9 0.4
Sensitivity / hurt feelings 1.6 2.8 8.9 1.6 1.8 1.1 1.1 1.5 0.2 2.2 2.5 1.9 0.6 1.9 1.4 1.5 1.4 0.3 1.5 2.1 1.9 -1.3 1.7 1.3 2.0 3.0 1.9 1.5 1.4 1.4 1.4 1.6 1.5 1.6 1.9 2.1 1.6 2.0 1.4
Frequency of depressed mood in last 2 weeks 0.5 0.7 2.6 0.9 -0.0 0.5 0.7 0.5 -0.6 1.1 1.4 0.7 -0.3 1.1 0.6 0.5 0.5 -0.4 0.5 0.8 1.1 -0.7 1.6 0.5 1.0 1.4 0.8 0.7 1.5 0.4 0.4 0.9 0.4 0.7 0.8 -0.6 0.6 0.8 0.4
Hearing difficulty/problems: Yes 0.9 1.4 5.8 -0.5 -1.7 -0.8 0.2 -0.8 -0.5 -1.8 -1.3 -1.4 -1.1 -0.6 -1.2 -0.6 -1.3 -0.3 -1.1 -1.4 -1.1 1.4 -1.6 -1.8 -0.4 -0.7 -1.1 -1.2 -2.4 -0.7 -0.8 -1.2 -1.6 -0.8 -1.1 -1.5 -1.1 -0.7 0.0
Relative age of first facial hair 0.3 0.5 6.3 -0.7 -0.2 -0.4 -0.7 -0.7 -1.5 -0.7 0.4 -0.7 -0.8 -0.1 -0.6 -0.9 -0.6 -0.9 -0.5 -0.4 0.2 0.2 -0.4 -0.1 -2.5 0.9 -0.3 -0.5 -0.0 0.0 -0.4 -0.1 0.4 -0.9 -0.1 -0.5 -0.3 -0.6 -1.2
Other serious medical condition/disability diagnosed by doctor 0.1 0.2 1.0 0.4 0.1 1.0 0.1 0.3 0.0 -0.2 0.8 -0.1 0.3 0.5 0.2 0.2 0.1 0.1 0.4 0.7 0.1 0.0 1.0 0.5 -0.7 0.7 0.1 0.2 -0.0 0.5 0.6 0.1 0.4 0.0 0.3 0.3 0.3 -0.0 0.1
Ever used hormone-replacement therapy (HRT) 0.5 0.6 2.9 0.2 0.8 1.4 0.6 0.5 1.2 0.1 -1.0 0.2 0.6 -0.0 0.6 0.4 0.2 0.7 0.7 -0.3 -1.5 -0.6 -0.1 0.1 -1.5 -1.7 -0.4 0.6 -0.2 0.7 0.5 -0.3 1.0 0.5 -0.4 1.2 0.8 -0.4 0.5
Ever had hysterectomy (womb removed) 0.1 0.1 0.7 0.1 -0.4 0.8 0.6 0.0 0.6 0.5 0.9 0.1 -0.3 0.3 0.1 0.1 0.4 -0.1 0.1 0.1 -0.5 -0.0 0.3 -0.3 0.4 -0.3 -0.4 0.1 -0.6 -0.0 0.2 -0.2 0.0 0.3 -0.3 -0.0 0.1 -0.1 0.6
Systolic blood pressure, automated reading 0.2 0.5 2.6 0.3 -1.6 1.0 -0.4 -0.4 -0.0 0.7 -0.0 -0.4 -1.5 0.4 -0.2 -0.5 -0.4 -1.5 -0.2 -0.4 -1.1 0.2 0.3 -1.1 -0.5 -0.9 -0.7 -0.1 -0.1 -0.6 -0.5 -0.7 0.5 -0.1 -0.8 0.7 -0.1 -0.8 -0.3
Eye problems/disorders: Diabetes related eye disease 2.2 2.4 4.5 -1.9 -1.4 -1.4 -1.7 -1.7 -1.4 -1.6 0.3 -1.9 -1.3 -1.2 -1.9 -1.7 -1.4 -1.4 -1.7 -1.3 -0.5 2.1 -1.3 -1.8 -1.4 -1.4 -1.4 -1.9 -0.8 -1.6 -1.8 -1.8 -1.8 -1.9 -1.6 -1.1 -1.9 -1.5 -1.7
Angina 0.6 0.7 5.0 0.6 0.3 2.2 0.7 0.3 0.9 0.6 1.9 0.4 0.3 1.4 0.5 0.3 0.7 0.3 0.4 1.1 -0.2 -0.5 1.2 0.1 -0.2 1.7 0.1 0.4 0.5 0.2 0.3 0.1 1.1 0.9 0.1 1.5 0.7 0.4 0.9
Medication for hormone replacement therapy 0.4 0.5 2.2 -0.4 -0.9 -1.1 -0.5 -0.5 -1.5 -0.8 -0.8 -0.3 -0.9 -0.7 -0.5 -0.6 -0.7 -0.5 -0.4 -0.7 0.8 0.4 -0.8 -0.6 -0.4 -0.2 -0.0 -0.5 -0.9 -0.6 -0.4 0.1 -1.0 -0.8 0.0 -0.5 -0.5 -0.4 -1.1
Vitamin and mineral supplements 0.1 0.2 0.7 0.1 0.7 0.7 0.2 0.4 0.3 0.7 0.6 0.4 -0.2 0.6 0.3 0.3 0.5 -0.2 0.4 0.3 0.5 -0.4 0.3 0.7 0.8 -0.5 0.3 0.3 -0.6 0.2 0.3 0.2 -0.1 0.2 0.3 0.4 0.3 0.2 0.1
Supplements: Zinc 0.5 0.6 3.6 -0.5 -0.8 -0.5 -0.9 -0.5 -0.4 -0.5 -1.0 -0.4 -0.5 -0.6 -0.5 -0.6 -0.4 -0.0 -0.5 -1.3 -0.8 0.7 -0.3 -1.0 -0.7 -0.9 -0.8 -0.5 -1.1 -1.0 -0.4 -0.5 -0.8 -0.6 -0.7 -1.9 -0.5 -0.7 -0.6
Medication: Co-codamol 0.2 0.2 1.4 0.8 0.1 1.2 0.6 0.3 0.9 0.9 -0.1 0.4 -0.0 0.4 0.5 0.3 0.2 0.2 0.2 -0.1 -0.6 -0.4 0.3 1.1 -0.2 -0.0 0.0 0.5 -0.3 0.0 0.2 0.2 0.4 0.6 -0.1 -0.8 0.3 0.2 0.6
Medication: Metformin 3.3 4.7 7.9 -2.4 -2.3 0.0 -1.8 -2.6 -0.7 -1.8 -1.8 -2.8 -2.4 -1.9 -2.6 -2.4 -2.2 -1.5 -2.7 -2.3 -1.9 2.7 -1.2 -0.2 -1.4 -1.9 -2.5 -2.6 -2.2 -2.6 -2.5 -2.7 -2.5 -2.1 -2.8 -1.9 -2.5 -2.1 -1.7
Diabetes (father) 0.8 0.9 2.2 -1.1 -0.5 -0.1 -0.7 -1.0 -0.2 -0.4 -1.1 -1.2 -0.9 -1.2 -1.0 -1.0 -1.1 -1.3 -1.0 -1.4 -1.5 0.5 -0.1 0.4 -0.4 -1.3 -1.4 -1.1 -1.2 -0.7 -0.9 -1.0 -0.6 -0.7 -1.4 -1.0 -0.9 -1.2 -0.6
Diabetes (mother) 0.2 0.3 1.2 -0.4 -0.8 0.4 0.0 -0.6 -0.1 0.0 0.3 -0.8 -1.1 -0.5 -0.4 -0.4 -0.2 -0.3 -0.5 -0.5 -0.4 0.2 0.6 0.1 0.8 -1.1 -0.8 -0.5 -0.4 -0.7 -0.8 -0.5 -0.5 -0.1 -0.8 -0.6 -0.4 -0.5 0.1
Severe depression (siblings) 0.4 0.5 2.9 -0.4 -0.5 -1.7 -0.0 -0.5 -1.2 -0.8 -0.7 -0.6 -0.9 -1.1 -0.3 -0.4 -0.5 0.4 -0.3 -0.6 1.2 0.3 -0.5 0.9 -0.1 -0.1 0.3 -0.3 0.3 -0.6 -0.6 0.3 -1.3 -0.7 0.2 -0.2 -0.6 0.1 -0.8
Pack years adult smoking proportion 1.4 2.1 8.8 1.1 1.2 2.0 1.3 1.1 1.3 0.7 3.0 1.0 0.7 1.8 1.2 1.1 1.4 0.6 1.1 2.7 0.8 -1.3 1.6 1.8 0.2 2.2 1.4 1.3 1.4 1.2 1.1 1.2 1.7 1.4 1.2 1.7 1.3 1.5 1.2
Impedance of leg (right) 2.8 13.6 22.9 4.0 4.8 3.2 3.8 4.2 3.4 4.2 3.3 4.2 4.4 3.3 4.0 4.0 4.2 3.8 3.9 4.0 2.7 -3.9 3.6 1.9 3.0 3.2 3.5 3.9 2.6 4.1 4.1 3.6 3.9 3.6 3.7 2.5 3.9 3.5 3.4
Leg fat-free mass (left) 1.3 6.8 11.7 -3.3 -3.4 -1.8 -2.2 -2.8 -2.4 -3.2 -2.5 -3.1 -2.0 -2.2 -2.8 -2.8 -3.0 -0.8 -2.8 -3.3 -2.1 2.5 -2.9 -2.9 -2.5 -2.7 -2.6 -2.8 -1.6 -2.5 -3.0 -2.7 -2.5 -2.4 -2.8 -1.7 -2.7 -2.5 -2.3
Trunk fat percentage 0.4 1.6 6.3 0.6 1.2 2.2 1.3 1.3 1.9 1.3 0.8 1.2 1.7 1.5 1.4 1.2 1.1 2.5 1.4 0.3 -1.2 -1.3 0.8 0.5 0.4 -0.2 0.5 1.4 0.5 1.2 1.1 0.6 2.0 1.6 0.4 0.9 1.4 0.8 1.6
Hand grip strength (right) 1.3 3.4 9.0 -1.5 -2.4 -2.6 -1.6 -1.5 -2.1 -2.7 -2.7 -2.0 -1.5 -3.0 -1.6 -1.6 -1.3 -1.6 -1.7 -2.2 1.3 1.4 -2.5 0.2 -1.7 -2.4 -0.7 -1.5 -1.5 -1.7 -1.6 -0.9 -2.6 -2.1 -1.0 -1.3 -1.8 -1.0 -2.3
Townsend deprivation index at recruitment 0.6 0.9 5.0 0.6 0.6 2.2 0.7 0.8 1.1 1.8 1.4 1.1 -0.0 1.3 1.2 0.8 1.0 -0.9 1.1 0.5 -0.7 -1.2 0.9 0.3 -0.1 -0.2 0.1 1.2 0.1 0.3 0.7 0.4 1.2 1.2 0.1 0.2 1.0 0.2 1.0
Current tobacco smoking 0.3 0.4 1.4 0.6 0.6 1.2 0.6 0.6 0.9 0.9 0.7 0.8 0.5 0.8 0.6 0.6 0.7 0.4 0.6 0.9 -0.0 -0.5 0.4 -0.2 0.8 0.7 0.4 0.6 0.1 0.4 0.4 0.4 0.7 0.8 0.5 0.5 0.6 0.7 0.8
Average weekly fortified wine intake 0.5 0.5 3.9 -0.9 -0.1 0.3 -0.9 -0.6 -0.1 -0.5 0.5 -0.8 0.0 0.5 -0.6 -0.6 -1.0 -0.0 -0.5 0.1 -2.0 0.6 0.3 -1.5 -0.6 0.1 -1.2 -0.6 0.7 0.1 -0.6 -1.1 0.5 -0.5 -0.9 0.0 -0.4 -1.2 -0.2
Maternal smoking around birth 0.4 0.6 4.5 -1.0 -0.1 1.0 -0.3 -0.6 -0.0 0.2 0.2 -0.6 -0.4 0.6 -0.5 -0.7 -0.6 -1.1 -0.5 -0.2 -2.1 0.4 -1.3 -0.3 -1.7 0.2 -1.2 -0.6 0.3 -0.2 -0.4 -1.2 0.5 -0.4 -1.0 0.1 -0.2 -1.2 -0.3
Fed-up feelings 4.8 8.7 17.6 3.4 2.9 3.3 3.6 3.4 2.2 4.2 1.9 3.4 2.8 3.0 3.4 3.3 3.3 0.6 3.2 3.0 1.5 -3.5 3.5 1.1 2.8 1.9 2.6 3.4 1.9 3.4 3.3 2.8 3.1 3.4 2.7 1.5 3.3 2.7 3.2
Frequency of unenthusiasm / disinterest in last 2 weeks 0.5 0.6 2.4 0.9 -0.6 0.4 0.9 0.6 -0.5 0.9 1.5 0.5 -0.6 1.1 0.7 0.6 0.5 -0.7 0.6 0.9 0.8 -0.7 1.5 -0.6 0.9 1.0 0.9 0.7 0.7 0.3 0.4 1.0 0.2 0.7 0.9 0.1 0.6 0.9 0.5
Relative age voice broke 0.7 1.0 8.0 -1.5 -0.2 -1.1 -1.4 -1.0 -1.2 -1.2 -0.8 -1.2 -0.8 -0.9 -0.9 -1.1 -0.9 -0.7 -0.6 -0.8 -0.6 0.7 -1.0 -0.3 -2.8 -0.4 -0.6 -0.8 0.4 -0.3 -0.8 -0.6 -0.1 -1.3 -0.5 -0.6 -0.7 -1.1 -1.7
Taking other prescription medications 0.8 1.2 2.2 1.3 0.8 1.2 1.3 1.3 0.9 1.0 0.6 1.0 0.9 1.0 1.4 1.3 1.4 0.5 1.3 0.6 0.8 -1.4 0.8 1.3 0.3 0.2 1.3 1.5 0.8 1.3 1.4 1.2 1.3 1.3 1.2 0.6 1.4 1.2 1.1
Age when periods started (menarche) 1.5 3.5 9.7 -1.4 -2.2 -3.1 -1.3 -1.7 -2.5 -2.6 -3.0 -1.8 -1.7 -2.0 -1.5 -1.9 -1.8 -1.1 -1.6 -2.4 0.3 0.8 -2.8 -1.0 -2.2 -1.8 -0.8 -1.5 -1.4 -1.5 -1.6 -0.6 -2.2 -2.3 -0.9 -1.7 -1.8 -1.5 -3.0
Bilateral oophorectomy (both ovaries removed) 0.3 0.3 4.1 -0.4 -0.6 -0.6 -0.1 -0.1 -0.2 0.1 -0.8 -0.0 -0.3 -0.9 -0.1 -0.1 -0.2 -0.8 -0.0 -0.6 0.1 -0.1 -0.7 -1.3 -0.4 -2.0 -0.0 -0.0 -1.2 0.2 -0.1 -0.1 -0.3 -0.3 -0.3 0.2 -0.2 -0.4 -0.5
Heel bone mineral density (BMD) T-score, automated (left) 0.5 1.0 11.4 -0.4 -0.8 -0.1 0.2 -0.1 -1.6 0.5 2.5 0.5 0.1 0.9 -0.0 -0.1 0.5 0.4 0.0 0.6 2.3 0.1 -0.8 -3.4 1.8 1.6 0.4 -0.1 0.3 -0.4 0.0 0.5 -0.4 -0.1 0.5 -0.6 -0.1 0.3 -0.1
Tinnitus: Yes, but not now, but have in the past 1.5 1.6 8.4 1.2 0.4 1.6 1.1 1.1 -0.1 1.7 2.9 1.1 0.6 2.2 1.0 1.1 1.1 0.3 1.1 1.5 1.1 -0.8 2.9 0.2 1.6 1.5 0.6 1.0 0.3 1.1 1.0 0.6 1.5 1.2 0.7 0.3 1.1 1.0 1.4
Qualifications: CSEs or equivalent 0.4 0.5 2.9 0.6 0.1 -0.2 0.9 0.4 -0.1 1.1 1.1 0.4 0.7 -0.4 0.5 0.5 0.5 0.3 0.4 0.6 1.7 -0.9 0.3 -0.8 0.4 0.7 0.8 0.4 1.2 0.6 0.2 0.8 0.0 0.4 0.9 1.3 0.3 0.6 0.2
Serious illness, injury or assault to yourself 0.5 0.7 2.4 0.4 1.0 0.9 0.2 0.6 0.6 0.5 1.6 0.4 0.9 1.5 0.6 0.6 0.7 0.4 0.6 0.8 -0.2 -0.4 1.4 0.2 0.1 1.2 0.2 0.6 1.6 1.1 0.8 0.3 1.6 0.5 0.5 0.7 0.8 0.4 0.5
High blood pressure 1.1 3.0 13.0 2.4 0.9 3.6 1.7 1.7 3.0 2.1 1.0 1.4 1.2 1.8 1.7 1.8 1.6 0.9 1.8 1.5 -0.9 -1.6 2.1 1.4 1.2 0.2 0.6 1.7 1.4 1.5 1.4 0.6 2.1 2.2 0.6 2.1 1.9 1.1 2.4
Hayfever, allergic rhinitis or eczema 0.9 1.9 4.9 -1.7 -1.2 -1.9 -1.5 -1.4 -1.9 -1.8 -1.1 -1.5 -0.9 -1.0 -1.3 -1.4 -1.3 -0.2 -1.5 -1.9 -0.3 1.1 -0.4 -1.6 -1.3 -0.9 -1.4 -1.4 -0.5 -0.9 -1.2 -0.9 -1.4 -1.7 -1.0 -2.2 -1.3 -1.6 -1.7
Multivitamins +/- minerals 0.4 0.5 2.4 1.0 -0.3 0.2 0.9 0.6 0.3 0.5 0.2 0.7 0.9 0.6 0.6 0.7 0.5 1.2 0.5 0.7 0.0 -0.3 0.5 -0.3 0.4 1.6 0.7 0.6 1.3 0.4 0.5 0.7 0.7 0.7 0.6 0.2 0.5 0.9 0.7
Stomach or abdominal pain in last month 0.2 0.3 4.6 0.1 0.2 0.5 -0.3 -0.2 0.1 1.1 1.0 -0.2 -0.9 0.2 -0.2 -0.2 0.0 -2.2 -0.3 0.1 0.2 0.0 0.7 0.3 -0.0 0.8 -0.2 -0.2 -0.1 -0.4 -0.3 0.0 -0.0 0.1 -0.0 0.1 -0.2 -0.0 -0.0
Supplements: Glucosamine 0.3 0.4 2.2 0.6 0.5 -0.1 0.2 0.2 0.4 -0.4 1.0 0.2 0.5 -0.5 0.3 0.3 0.5 1.1 0.2 0.8 0.5 -0.2 0.9 1.0 0.8 0.9 0.3 0.3 1.5 0.2 0.2 0.3 0.2 0.3 0.4 0.9 0.2 0.5 0.6
Diverticular disease/diverticulitis (self-reported) 1.8 2.1 4.5 1.6 0.9 1.9 1.9 1.6 1.7 1.6 1.2 1.7 1.0 1.6 1.5 1.7 1.5 1.2 1.6 1.6 0.2 -1.1 0.3 -0.3 1.3 2.1 1.2 1.5 1.1 1.2 1.5 1.2 1.5 1.8 1.3 1.2 1.6 1.7 2.1
Medication: Atenolol 0.9 1.1 3.2 1.6 0.5 1.7 1.5 1.0 1.3 1.8 0.3 1.1 0.7 0.6 1.1 1.2 1.2 -0.4 0.9 0.6 0.7 -1.2 1.5 -0.5 1.7 0.0 0.6 1.0 0.2 0.7 1.0 0.7 0.5 1.4 0.6 1.0 1.0 0.8 1.7
Medication: Levothyroxine sodium 7.1 12.1 22.3 3.4 4.1 4.1 3.1 3.8 3.0 4.6 3.2 3.9 3.0 4.1 3.8 3.7 4.0 1.5 3.9 3.3 1.6 -3.5 4.7 2.2 3.0 2.5 2.8 4.0 2.7 3.6 3.9 3.0 4.3 3.9 3.0 2.5 3.9 2.9 3.8
Sitting height 0.2 1.1 6.2 -1.2 -0.5 -0.7 -0.0 -0.7 -0.1 -2.3 -1.6 -1.1 1.3 -1.0 -0.8 -0.6 -0.8 2.5 -1.1 -1.3 -0.3 0.3 -1.4 -2.4 -0.6 -0.6 -0.5 -1.0 -1.0 -0.1 -0.6 -0.4 -0.7 -0.6 -0.5 -0.6 -0.7 -0.2 -0.3
Chronic bronchitis/emphysema (father) 0.8 1.0 3.5 0.9 0.5 1.8 0.9 0.6 0.7 1.6 1.8 0.4 -0.5 1.4 0.9 0.6 1.0 -0.6 0.8 1.2 -0.1 -1.0 1.4 0.6 -0.1 1.5 0.2 0.9 1.9 0.4 0.5 0.5 1.3 1.0 0.5 1.2 0.8 0.3 0.8
High blood pressure (mother) 0.1 0.2 1.0 0.2 -0.8 -0.2 -0.1 -0.2 -0.4 0.2 -0.6 -0.4 -0.1 -0.7 -0.1 -0.2 -0.1 -0.7 -0.1 0.2 0.5 0.3 -0.4 0.2 -0.3 -0.3 -0.2 -0.2 1.0 -0.2 -0.4 -0.3 -0.3 -0.4 -0.1 0.7 -0.3 -0.4 -0.5
Body mass index (BMI) 0.1 0.5 3.6 -0.6 -1.0 0.6 -0.3 -0.4 0.3 -0.0 -0.6 -0.5 -0.7 0.2 -0.3 -0.4 -0.6 -0.4 -0.2 -1.0 -1.9 0.6 -0.9 0.3 -0.8 -1.5 -0.8 -0.1 -0.5 -0.6 -0.5 -0.9 0.0 -0.0 -1.0 0.0 -0.2 -0.6 0.1
Impedance of leg (left) 2.0 9.5 17.8 3.2 4.2 2.8 3.0 3.4 3.0 3.5 3.0 3.5 3.7 2.7 3.3 3.3 3.4 3.5 3.2 3.4 2.0 -3.2 3.1 1.7 2.9 2.9 2.9 3.1 2.1 3.3 3.4 2.9 3.3 3.0 3.0 2.0 3.1 2.9 2.8
Leg predicted mass (left) 1.2 6.2 10.8 -3.1 -3.3 -1.7 -2.0 -2.7 -2.2 -3.1 -2.4 -2.9 -1.9 -2.1 -2.6 -2.6 -2.8 -0.8 -2.6 -3.2 -2.0 2.3 -2.8 -2.8 -2.4 -2.7 -2.5 -2.6 -1.5 -2.4 -2.8 -2.5 -2.3 -2.3 -2.7 -1.5 -2.5 -2.3 -2.2
Trunk fat mass 0.1 0.4 3.2 -0.5 -0.1 1.1 0.3 0.2 0.9 0.1 -0.4 0.1 0.7 0.5 0.4 0.1 0.0 1.8 0.3 -0.9 -1.6 -0.4 -0.3 -0.4 -0.5 -1.3 -0.4 0.3 -0.3 0.1 0.0 -0.3 0.8 0.6 -0.6 0.3 0.4 -0.1 0.5
Waist circumference 0.1 0.5 4.2 -0.2 -0.6 1.8 0.1 -0.1 0.8 0.7 0.6 -0.1 -0.2 1.0 0.1 -0.1 -0.0 0.3 0.2 -0.7 -2.0 0.1 0.3 -0.7 0.1 -0.9 -1.0 0.1 -0.1 -0.3 -0.3 -0.9 0.7 0.6 -1.0 0.1 0.2 -0.5 0.8
Number of incorrect matches in round 3.0 5.0 9.6 -2.0 -1.6 -2.4 -2.5 -2.5 -2.1 -2.8 -1.5 -2.7 -2.8 -1.7 -2.7 -2.4 -2.4 -2.6 -2.6 -2.3 -1.5 3.1 -1.7 -1.1 -1.6 -1.5 -2.4 -2.6 -1.6 -2.1 -2.4 -2.8 -2.3 -2.4 -2.5 -1.6 -2.5 -2.3 -1.6
Past tobacco smoking 0.2 0.5 1.2 0.9 0.9 -0.2 0.5 1.0 1.1 0.7 -0.1 0.5 0.9 0.7 0.7 1.0 0.5 0.0 0.9 0.4 -0.1 -0.6 0.3 0.5 1.0 -0.6 0.4 0.8 0.6 1.1 1.0 0.7 0.5 0.5 0.6 0.2 0.6 0.3 0.6
Alcohol usually taken with meals 1.0 1.7 3.7 -1.2 -0.9 -1.9 -1.5 -1.3 -1.3 -1.4 -0.5 -1.2 -0.9 -1.4 -1.5 -1.2 -1.0 -0.7 -1.2 -1.2 -0.6 1.9 -1.2 -1.5 -0.7 -1.6 -1.3 -1.5 -1.0 -1.0 -1.2 -1.5 -1.4 -1.6 -1.3 -1.2 -1.4 -1.4 -1.2
Nervous feelings 0.4 0.7 2.5 1.2 0.2 -0.2 0.5 0.8 -0.2 1.1 0.8 0.7 -0.6 0.5 0.8 0.6 0.8 -1.0 0.9 0.5 1.6 -1.4 1.1 0.8 0.1 1.0 1.3 0.8 0.7 0.4 0.7 1.6 0.4 0.6 1.3 0.8 0.8 0.9 -0.2
Frequency of tenseness / restlessness in last 2 weeks 0.4 0.6 2.1 1.1 0.2 0.8 1.0 0.8 0.6 1.5 0.7 0.8 -0.0 0.4 0.8 0.9 0.9 -0.4 0.7 0.6 0.3 -0.6 1.2 0.8 1.3 0.0 0.8 0.9 0.8 0.4 0.6 0.7 0.5 1.0 0.5 -0.0 0.7 0.9 0.8
Hearing difficulty/problems with background noise 1.0 1.7 4.7 -1.2 -1.3 -1.0 -0.8 -1.2 -2.0 -1.5 0.2 -1.5 -1.5 -0.1 -1.6 -1.2 -1.6 -1.6 -1.4 -0.7 -0.6 1.8 -0.3 -1.3 -0.5 0.2 -1.4 -1.5 -2.2 -0.8 -1.2 -1.5 -1.2 -1.3 -1.3 -1.7 -1.4 -1.2 -0.7
Hair/balding pattern: Pattern 2 0.5 0.6 2.5 0.5 0.9 0.6 0.9 0.8 0.3 1.2 0.9 0.6 1.3 -0.7 0.5 0.8 0.8 0.0 0.6 1.5 0.9 -0.4 0.3 1.6 0.2 0.4 0.8 0.6 1.0 1.3 0.7 0.3 0.8 0.6 0.5 1.0 0.5 0.6 0.7
Had menopause 1.6 2.0 8.0 -1.6 -0.9 -0.6 -1.8 -1.2 -0.9 -1.9 -1.3 -1.4 -1.5 -1.3 -1.2 -1.3 -1.3 -0.8 -1.1 -1.9 -1.7 1.5 -2.4 -0.7 -2.8 -1.6 -1.5 -1.1 -0.8 -1.2 -1.1 -1.5 -0.8 -1.3 -1.6 -1.0 -1.1 -1.7 -1.3
Had other major operations 0.2 0.2 1.0 0.7 -0.0 -0.8 0.2 0.6 -0.6 -0.6 -0.2 0.2 0.4 0.7 0.3 0.5 0.1 0.5 0.3 0.2 1.0 0.2 -0.4 0.4 -0.2 0.8 0.7 0.3 0.1 0.6 0.6 0.5 0.0 0.0 0.6 -0.8 0.2 0.6 0.2
Forced vital capacity (FVC) 1.9 7.4 20.2 -3.2 -2.7 -2.9 -2.1 -2.7 -3.1 -3.8 -2.8 -2.7 -1.6 -2.5 -2.9 -2.7 -2.6 -0.4 -3.0 -3.3 -1.1 2.5 -3.6 -4.5 -1.9 -2.4 -2.4 -3.1 -2.6 -2.2 -2.7 -2.4 -2.9 -2.8 -2.5 -2.7 -2.8 -2.4 -2.7
Heel bone mineral density (BMD) T-score, automated (right) 0.4 1.0 7.7 -0.1 0.4 -0.0 0.3 0.6 -1.2 1.1 1.8 1.1 1.1 1.2 0.5 0.4 0.9 1.2 0.5 0.6 2.2 -0.3 -0.2 -2.8 2.3 1.0 0.6 0.4 0.4 0.7 0.8 0.8 0.4 0.3 0.8 -0.5 0.5 0.4 0.3
Ever unenthusiastic/disinterested for a whole week 2.7 3.3 5.7 2.0 2.0 2.4 1.6 2.0 1.5 1.8 0.9 2.0 1.5 2.0 2.0 2.0 2.2 0.7 2.0 2.0 1.8 -1.6 1.7 1.8 2.3 1.7 2.0 2.0 0.5 1.6 2.0 1.8 1.8 2.0 1.9 0.8 1.9 2.1 1.8
Qualifications: None of the above 1.9 4.1 8.1 2.6 2.2 2.0 2.1 2.2 2.5 2.5 1.4 2.5 1.6 2.8 2.3 2.2 2.0 1.6 2.3 1.9 0.4 -2.1 1.3 1.6 0.9 1.8 1.8 2.3 1.5 1.8 2.0 2.0 2.2 2.4 2.0 1.6 2.3 1.9 2.3
Financial difficulties in last 2 years 0.6 0.9 3.5 -0.4 -1.3 -0.8 -0.3 -1.0 -1.6 -0.3 0.5 -0.6 -1.2 -0.2 -0.9 -0.8 -0.7 -0.3 -1.2 -0.8 1.0 0.8 0.5 -1.7 1.3 0.6 -0.7 -0.9 -0.6 -1.3 -1.2 -0.4 -1.5 -0.5 -0.5 -1.9 -1.0 -0.2 -0.1
Mouth/teeth dental problems 0.9 1.4 4.5 -0.8 -1.0 -1.9 -1.1 -1.2 -0.7 -2.1 -1.2 -1.4 -0.9 -1.0 -1.4 -1.1 -1.3 0.3 -1.3 -1.1 -0.8 1.8 -1.7 -0.2 -0.9 -0.3 -0.8 -1.4 -1.0 -1.2 -1.1 -1.2 -1.6 -1.3 -0.9 -0.5 -1.3 -0.6 -0.9
Heart attack 0.4 0.5 3.2 -0.0 0.7 1.8 0.7 0.4 1.1 0.8 -0.1 0.4 0.4 0.6 0.5 0.5 0.3 -0.1 0.5 0.7 -1.3 -0.4 1.0 0.2 0.7 0.0 -0.3 0.5 -0.0 0.5 0.3 -0.3 1.0 1.0 -0.4 1.0 0.6 0.1 1.2
Allergy 1.4 3.2 7.0 2.2 1.4 2.2 1.9 1.8 2.6 2.1 1.4 2.2 1.6 1.5 1.8 1.9 1.7 1.5 1.8 2.4 0.3 -1.5 0.5 1.7 1.7 1.6 1.8 1.8 0.9 1.1 1.6 1.5 1.7 2.2 1.5 2.4 1.8 2.2 2.2
Pain all over the body in last month 1.4 1.5 5.2 1.5 0.8 1.4 1.8 1.2 1.1 1.5 0.9 1.0 1.2 0.9 1.1 1.4 1.1 0.4 1.0 1.4 1.0 -1.1 1.9 -0.1 2.3 0.5 1.2 0.9 -0.5 1.3 1.0 0.9 0.8 1.4 0.9 1.2 0.9 1.4 1.8
Diabetes (self-reported) 0.8 1.2 2.9 -1.0 -1.1 0.3 -0.7 -1.4 -0.1 -0.7 -0.0 -1.4 -1.7 -0.9 -1.3 -1.2 -1.0 -1.1 -1.5 -0.7 -0.5 1.3 -0.3 1.1 -0.4 -0.7 -1.1 -1.3 -1.6 -1.7 -1.5 -1.4 -1.5 -0.8 -1.4 -0.9 -1.3 -0.8 -0.4
Hayfever/allergic rhinitis (self-reported) 0.6 0.7 3.0 0.6 1.1 0.4 0.8 0.8 0.6 0.6 1.7 0.9 1.0 1.1 0.8 0.9 0.9 0.9 0.6 0.9 1.0 -0.8 0.9 0.5 1.4 0.9 0.5 0.8 0.6 0.7 0.8 0.8 0.4 0.9 0.9 -0.1 0.7 0.8 1.1
Medication: Ramipril 0.5 0.7 3.5 -0.5 -0.1 0.8 -0.1 -0.3 1.1 -0.3 -1.8 -0.8 0.4 -0.9 -0.3 -0.3 -0.4 0.7 -0.5 -0.9 -1.9 0.4 -0.6 1.3 -1.2 -1.4 -1.2 -0.3 -0.6 -0.0 -0.5 -1.1 0.0 -0.2 -1.2 0.0 -0.2 -1.0 0.1
Medication: Simvastatin 0.5 0.7 2.1 1.1 -0.3 1.0 0.8 0.8 0.1 1.2 -0.0 0.9 -0.4 -0.1 1.2 0.6 1.3 -1.2 1.1 0.3 1.3 -1.5 0.2 0.4 -0.8 -0.3 1.2 1.3 -0.3 0.2 0.8 1.3 0.7 0.9 0.9 0.7 1.1 0.8 0.2
Fluid intelligence score 0.1 0.2 0.8 -0.5 0.6 0.2 -0.6 0.1 0.0 0.5 0.9 0.4 0.5 0.0 0.2 -0.0 0.5 0.8 0.2 0.1 0.0 -0.2 0.7 0.9 -0.0 -0.3 -0.0 0.2 -0.1 -0.1 -0.0 0.0 0.4 0.1 -0.1 -0.5 0.2 -0.2 -0.2
Illnesses of siblings 0.5 0.7 3.0 0.5 0.6 -1.7 0.6 0.5 -0.4 -0.8 -0.5 0.6 0.7 -0.3 0.4 0.4 0.5 0.7 0.3 0.3 1.7 -0.8 -1.2 1.1 0.1 0.8 1.5 0.4 0.2 0.7 0.6 1.3 -0.4 -0.1 1.5 0.8 0.4 1.0 -0.5
Neuroticism score 1.8 3.7 10.2 2.1 1.5 1.9 1.9 2.0 0.2 3.2 1.8 2.2 1.0 2.0 2.1 1.8 1.7 -0.6 2.0 2.1 1.8 -2.4 3.1 0.3 2.1 2.0 1.9 2.0 1.4 2.0 1.9 2.2 2.0 2.0 1.9 1.1 2.0 1.7 1.3
Weight 0.5 2.6 5.7 -2.2 -2.0 -0.4 -1.2 -1.6 -0.8 -1.7 -1.7 -1.8 -1.0 -1.1 -1.5 -1.6 -1.8 0.1 -1.5 -2.4 -2.4 1.4 -2.1 -1.6 -1.7 -2.3 -1.9 -1.5 -1.3 -1.5 -1.7 -2.0 -1.1 -1.2 -2.1 -0.9 -1.4 -1.7 -1.0
Impedance of arm (right) 2.0 9.1 16.2 2.3 3.8 2.8 3.1 3.2 2.3 3.1 3.1 3.4 3.7 2.9 3.1 3.0 3.2 4.0 2.8 3.3 2.3 -3.5 3.3 0.2 2.4 4.0 2.8 2.9 2.3 3.0 3.1 3.2 3.3 3.0 3.1 1.6 3.1 3.0 2.6
Arm fat percentage (right) 0.4 1.5 5.4 0.5 0.8 2.3 1.3 1.2 1.7 1.6 0.9 1.3 1.1 1.7 1.4 1.2 1.1 1.7 1.4 0.6 -1.0 -1.2 0.9 0.8 0.5 0.2 0.6 1.4 0.7 0.8 1.0 0.6 1.9 1.6 0.4 1.3 1.4 0.8 1.5
Trunk fat-free mass 1.4 8.0 14.0 -3.2 -3.7 -2.3 -2.5 -3.0 -2.5 -3.5 -3.1 -3.2 -2.4 -3.1 -2.9 -3.0 -3.0 -1.4 -2.9 -3.5 -1.8 2.5 -3.1 -3.0 -2.6 -3.5 -2.7 -2.9 -1.9 -2.7 -3.0 -2.7 -2.9 -2.8 -2.9 -1.4 -2.8 -2.8 -2.8
Hip circumference 0.1 0.2 1.1 -1.1 -0.1 0.6 0.2 -0.1 0.2 0.4 0.5 -0.0 0.8 0.3 -0.0 -0.1 -0.1 0.8 0.1 -0.3 -1.1 0.1 -0.5 -0.4 -0.6 -0.7 -0.5 -0.0 -0.0 0.0 -0.2 -0.6 0.6 0.2 -0.6 0.9 0.0 -0.3 0.3
Time employed in main current job 1.0 1.2 3.3 -0.6 0.2 -1.2 -1.0 -0.7 -0.5 -1.2 -1.2 -0.9 -1.3 -0.3 -1.1 -0.7 -1.1 -0.3 -0.9 -1.8 -1.5 1.6 -1.4 0.9 -0.2 -1.8 -1.0 -1.0 -1.7 -0.8 -0.7 -1.3 -1.1 -1.0 -1.2 -1.2 -0.9 -0.9 -0.4
Alcohol intake versus 10 years previously 0.2 0.2 0.9 -0.9 0.3 0.3 -0.9 -0.5 0.1 0.5 -0.4 -0.4 0.3 -0.8 -0.4 -0.6 -0.6 -0.9 -0.4 -0.0 -0.2 -0.3 -0.0 -0.0 -0.6 -0.4 -0.6 -0.4 0.1 -0.1 -0.5 -0.2 0.2 -0.4 -0.4 -0.3 -0.3 -0.8 -0.7
Father’s age at death 2.3 3.0 4.4 -1.7 -1.4 -1.9 -2.0 -2.0 -1.9 -2.0 -1.7 -1.9 -1.6 -1.4 -2.0 -1.9 -1.9 -1.4 -1.8 -1.9 -0.5 2.1 -1.6 -2.1 -0.6 -1.5 -1.7 -1.9 -1.2 -1.7 -1.9 -1.7 -1.9 -1.9 -1.7 -1.6 -1.9 -1.7 -1.6
Worrier / anxious feelings 1.2 2.3 14.1 1.6 0.2 -0.5 1.3 1.0 -1.9 1.3 1.9 1.2 -0.0 1.2 1.3 0.9 1.3 -1.2 1.3 1.7 3.7 -1.8 1.8 -0.1 0.7 1.8 2.3 1.3 2.0 1.1 1.0 2.3 0.8 0.7 2.2 2.1 1.1 1.5 -0.3
Frequency of tiredness / lethargy in last 2 weeks 0.4 0.7 3.8 0.6 0.6 1.8 0.6 0.7 0.9 1.4 -0.3 0.7 -0.3 0.7 0.6 0.8 0.6 -2.0 0.7 0.2 -0.9 -0.2 1.1 0.1 1.6 -0.6 0.0 0.7 -1.2 0.2 0.6 0.0 0.6 1.1 -0.3 -0.7 0.5 0.4 1.2
Falls in the last year 0.6 0.9 6.6 0.1 0.1 2.6 0.4 0.4 1.2 1.2 0.1 0.5 -0.7 1.7 0.7 0.3 0.5 -0.2 0.8 0.3 -2.0 -0.7 1.2 1.5 -0.7 0.7 -0.5 0.7 0.2 -0.3 0.5 -0.3 1.5 1.1 -0.5 0.5 0.9 -0.2 1.0
Hair/balding pattern: Pattern 3 0.4 0.6 1.7 -1.3 -0.6 -0.0 -0.4 -1.1 -0.1 -0.9 0.0 -1.0 -0.8 -0.6 -0.9 -1.1 -0.7 0.4 -1.0 -1.0 -0.2 0.5 -0.6 0.2 -1.3 -0.2 -1.1 -1.1 -0.6 -1.3 -1.1 -0.7 -0.7 -0.7 -0.9 0.3 -0.8 -0.9 -0.7
Number of live births 2.8 3.9 8.9 2.5 2.0 1.4 1.6 2.0 1.2 2.9 1.9 2.6 1.0 2.2 2.1 1.9 2.0 1.0 2.1 1.7 1.5 -2.0 3.0 2.2 2.5 2.3 1.9 2.1 1.4 1.4 2.0 2.1 1.9 2.1 2.1 1.1 2.0 2.0 1.8
Forced expiratory volume in 1-second (FEV1) 0.3 0.9 11.7 -0.1 -0.4 -1.4 0.8 0.3 -1.1 -1.1 -0.8 0.6 1.2 0.1 0.1 0.2 0.3 2.0 -0.0 -0.6 1.5 -0.3 -1.6 -3.4 0.9 -0.1 0.7 -0.0 -0.7 0.5 0.2 0.5 -0.3 -0.1 0.6 -0.3 0.1 0.6 -0.2
Pulse rate 0.4 0.7 2.3 -1.4 -0.3 -0.5 -0.8 -1.1 -0.7 -0.4 -0.6 -1.1 -0.8 -1.3 -1.0 -1.0 -0.9 -1.5 -1.1 -0.6 -0.2 0.6 -0.1 -0.7 -0.6 -0.3 -0.7 -1.0 0.2 -0.6 -1.1 -0.6 -0.7 -0.7 -0.7 -0.4 -0.9 -0.8 -0.8
Happiness 0.3 0.4 2.4 0.4 -0.8 1.1 0.1 0.1 -0.4 0.6 0.6 0.2 -1.1 1.1 0.1 0.1 0.3 -1.5 0.2 0.9 -0.6 -0.0 0.4 -0.9 -0.5 1.5 0.0 0.2 0.5 -0.3 0.1 0.1 0.7 0.5 0.0 -0.1 0.3 0.3 0.4
Noisy workplace 0.2 0.3 0.8 -0.2 -0.3 -0.1 -0.4 -0.3 -0.4 -0.7 0.9 -0.6 -0.4 0.6 -0.5 -0.3 -0.6 -0.2 -0.5 -0.0 -0.9 0.9 -0.3 -0.7 -0.8 0.6 -0.5 -0.4 0.5 -0.2 -0.4 -0.7 -0.2 -0.5 -0.4 -0.3 -0.4 -0.5 -0.2
Qualifications: A levels/AS levels or equivalent 0.5 1.2 4.1 -1.3 -0.5 -1.2 -1.2 -0.9 -0.5 -1.3 -2.0 -1.2 -0.9 -1.0 -0.9 -0.9 -0.8 -0.4 -0.8 -2.0 -1.3 0.9 -0.8 -0.8 -1.1 -1.4 -1.2 -0.8 -0.6 -0.7 -0.6 -1.2 -0.7 -1.1 -1.1 -1.4 -0.8 -1.2 -1.0
Serious illness, injury or assault of a close relative in last 2 years 1.3 1.5 4.3 1.2 0.7 2.0 1.2 1.1 1.4 1.5 1.2 1.2 1.4 2.1 1.0 1.1 0.9 2.0 0.9 1.4 -0.6 -0.6 1.4 -0.5 1.7 1.6 0.5 0.9 1.1 1.0 1.0 0.3 1.4 1.2 0.6 0.7 1.1 0.8 1.5
Mouth/teeth dental problems: Dentures 0.7 1.1 5.2 0.8 0.9 2.2 0.9 0.9 1.2 1.9 1.0 1.5 0.9 1.1 1.0 1.0 1.2 0.8 0.7 0.8 0.2 -0.9 1.1 -0.6 2.3 0.1 0.3 1.0 -0.2 0.8 0.8 0.5 1.1 1.3 0.3 -0.7 1.0 0.6 1.4
Asthma 0.3 0.7 4.8 -0.1 0.1 -1.8 -0.3 -0.1 -1.3 -0.5 -0.3 -0.3 -0.7 -1.6 0.0 -0.1 -0.0 -1.9 0.2 -0.4 2.2 -0.2 -0.8 1.2 -0.2 -1.0 0.9 0.2 0.2 0.1 -0.0 0.8 -0.8 -0.6 0.8 -0.0 -0.2 0.4 -1.0
Medication: Ibuprofen (e.g. Nurofen) 0.2 0.2 2.6 -0.1 0.8 0.8 0.4 0.1 0.1 0.6 -0.3 0.2 0.3 0.7 0.1 0.1 0.0 -0.5 0.0 0.4 -0.3 -0.2 0.3 -0.6 1.6 0.3 -0.4 0.0 0.1 0.3 0.2 -0.1 0.3 0.2 -0.1 0.1 0.1 -0.2 0.4
Medication: Cholesterol lowering 0.1 0.2 1.9 0.2 -0.8 0.3 0.1 -0.3 -0.2 -0.4 0.7 -0.5 -0.8 -0.2 -0.1 -0.3 0.2 -0.3 -0.1 -0.2 -0.2 -0.1 0.4 0.3 -1.4 -0.5 -0.3 -0.1 -0.5 -0.6 -0.3 -0.3 -0.1 -0.0 -0.5 0.5 -0.1 -0.3 -0.2
Depression (self-reported) 0.2 0.3 1.4 -0.4 -0.2 1.0 0.0 -0.1 0.1 0.4 0.8 -0.0 -0.2 1.2 -0.2 0.0 -0.1 -0.2 -0.1 0.3 -1.0 0.8 -0.4 -0.9 0.3 1.1 -0.5 -0.1 0.3 -0.4 -0.2 -0.9 0.2 0.2 -0.5 -0.1 -0.0 -0.1 0.7
Medication: Lansoprazole 0.9 1.1 2.4 0.4 1.4 1.5 0.5 1.1 0.8 1.4 0.8 1.2 1.3 1.6 1.1 1.0 1.0 1.1 1.1 1.1 0.0 -0.8 1.3 1.4 0.9 0.7 0.6 1.2 0.3 1.1 1.1 0.7 1.4 1.0 0.6 -0.4 1.1 0.6 1.0
Prospective memory result 0.6 0.8 2.6 -0.6 -0.8 -1.6 -0.6 -0.8 -1.1 -0.9 -1.4 -0.8 -0.5 -0.2 -0.7 -0.8 -1.2 -1.1 -0.8 -1.0 -0.0 0.6 -0.6 -0.8 -0.9 -0.6 -0.6 -0.7 -1.4 -0.5 -0.5 -0.3 -1.0 -1.1 -0.4 -1.2 -0.8 -0.7 -1.0
Lung cancer (father) 2.5 2.9 5.9 -1.7 -1.4 -2.0 -2.2 -1.6 -1.7 -1.4 -1.3 -1.5 -1.5 -1.8 -1.9 -1.7 -1.7 -1.8 -1.6 -2.2 -0.9 2.2 -2.4 -0.7 -1.0 -1.6 -1.4 -1.8 -2.0 -1.4 -1.4 -1.9 -1.6 -1.9 -1.7 -1.9 -1.7 -1.6 -1.8
Illnesses of mother 0.3 0.3 2.3 -0.1 0.9 0.0 -0.3 0.2 0.8 0.2 1.3 0.5 0.8 0.8 0.0 0.3 0.0 1.5 0.1 0.7 -0.3 0.4 0.0 0.3 0.6 1.4 0.2 0.1 0.8 0.1 0.1 -0.0 0.3 0.2 0.3 0.1 0.1 0.5 0.4
Forced expiratory volume in 1-second (FEV1), Best measure 0.8 2.4 11.5 1.3 0.8 -0.3 2.3 1.6 0.3 -0.2 0.3 1.8 2.8 1.0 1.4 1.5 1.4 3.4 1.1 0.8 2.3 -1.8 -0.5 -2.1 1.7 1.1 2.0 1.1 0.4 1.9 1.4 1.9 0.8 1.2 2.0 0.7 1.3 1.9 1.0
Pulse wave Arterial Stiffness index 0.5 0.6 2.9 0.8 0.7 1.6 0.8 0.6 0.9 1.3 -0.2 0.6 0.4 1.1 0.7 0.6 0.3 -0.4 0.7 0.7 -1.7 -0.7 0.4 -0.7 -0.1 0.0 -0.1 0.6 0.7 0.6 0.6 -0.1 0.9 1.0 -0.0 0.7 0.7 0.0 1.1
Impedance of arm (left) 1.7 7.7 14.9 2.0 3.8 2.8 2.7 2.9 2.3 2.8 2.8 3.0 3.6 2.8 2.9 2.8 3.0 3.9 2.5 2.9 1.8 -3.2 3.2 0.2 2.0 3.5 2.4 2.6 1.9 2.9 2.9 2.8 3.2 2.8 2.7 1.3 2.9 2.6 2.5
Arm fat mass (right) 0.1 0.3 2.1 -0.6 -0.4 1.3 0.3 0.1 0.6 0.3 -0.3 0.0 0.2 0.4 0.2 0.1 -0.1 0.8 0.3 -0.6 -1.5 -0.2 -0.3 -0.3 -0.4 -1.1 -0.4 0.3 -0.3 -0.1 -0.1 -0.4 0.6 0.5 -0.6 0.3 0.3 -0.2 0.5
Trunk predicted mass 1.4 8.2 14.0 -3.2 -3.7 -2.4 -2.5 -3.0 -2.6 -3.5 -3.2 -3.3 -2.4 -3.1 -2.9 -3.0 -3.0 -1.4 -2.9 -3.6 -1.7 2.5 -3.1 -3.0 -2.7 -3.6 -2.8 -3.0 -1.9 -2.8 -3.1 -2.7 -2.9 -2.9 -2.9 -1.5 -2.9 -2.9 -2.9
Standing height 0.5 5.2 14.1 -3.2 -1.9 -1.8 -1.7 -2.3 -1.9 -3.5 -2.5 -2.6 -0.5 -2.7 -2.4 -2.3 -2.4 1.4 -2.6 -2.9 -1.1 1.6 -2.5 -3.8 -2.1 -1.9 -2.2 -2.7 -1.7 -1.7 -2.3 -2.0 -2.1 -2.2 -2.2 -1.8 -2.3 -2.0 -2.2
Length of working week for main job 0.4 0.4 1.5 -1.0 -0.4 -0.1 -0.7 -0.7 -0.6 -1.2 0.2 -0.8 -0.2 0.0 -0.8 -0.7 -0.7 0.6 -0.8 -0.3 -0.4 1.0 -0.6 -0.6 -0.6 0.1 -0.6 -0.7 0.5 -0.5 -0.6 -0.9 -0.4 -0.8 -0.6 -0.8 -0.7 -0.5 -0.6
Exposure to tobacco smoke at home 1.1 1.2 3.1 0.9 1.2 0.2 0.8 1.3 0.5 0.6 1.1 1.3 0.9 1.5 1.2 1.1 1.1 0.7 1.4 1.1 1.3 -1.0 0.8 1.6 -0.2 1.8 1.3 1.2 0.8 1.2 1.5 1.4 1.3 0.8 1.4 -0.1 1.2 1.2 0.7
Breastfed as a baby 2.0 2.5 4.4 -1.5 -1.2 -1.5 -1.6 -1.7 -1.0 -2.1 -2.1 -2.0 -1.4 -1.7 -1.7 -1.6 -2.1 -1.1 -1.7 -1.6 -1.8 1.7 -1.9 -0.5 -1.2 -1.2 -1.7 -1.6 -0.9 -1.3 -1.7 -1.8 -1.5 -1.7 -1.6 -0.6 -1.6 -1.7 -1.3
Tense / ‘highly strung’ 0.3 0.4 2.8 0.3 -0.3 -0.1 0.1 0.2 -1.3 0.5 1.0 0.5 -0.9 0.7 0.3 0.0 0.2 -0.7 0.4 0.3 1.0 -0.7 1.7 -0.0 0.8 1.3 0.7 0.3 0.1 -0.1 0.3 1.0 0.2 0.2 0.7 -0.9 0.4 0.4 -0.4
Seen doctor (GP) for nerves, anxiety, tension or depression 1.0 1.5 2.7 1.1 1.5 1.4 1.2 1.3 1.0 1.4 0.8 1.4 1.2 1.2 1.5 1.3 1.5 0.7 1.5 0.8 0.4 -1.4 0.5 0.7 0.8 0.5 1.2 1.5 1.3 1.5 1.3 1.1 1.6 1.4 1.2 0.8 1.5 1.2 1.1
Hair/balding pattern: Pattern 4 0.7 1.6 7.0 -1.3 0.4 -1.0 -1.1 -1.1 0.1 -1.6 -2.6 -1.3 -0.9 -2.1 -0.9 -1.0 -1.1 0.4 -1.2 -1.7 -0.7 1.0 -1.1 1.2 -0.4 -2.6 -0.9 -1.1 -1.1 -1.4 -1.2 -1.0 -2.1 -1.1 -1.1 -1.2 -1.3 -0.9 -0.9
Birth weight of first child 1.8 3.4 5.8 -2.3 -1.0 -1.3 -2.1 -2.1 -1.0 -2.0 -1.0 -2.4 -1.9 -1.8 -2.3 -2.1 -2.2 -0.9 -2.2 -1.6 -2.3 2.2 -1.0 0.3 -1.1 -0.9 -2.3 -2.3 -0.5 -1.6 -2.2 -2.3 -1.6 -1.9 -2.3 -1.7 -2.1 -2.2 -1.6
Peak expiratory flow (PEF) 0.2 0.5 3.3 0.5 -0.2 -0.5 1.3 0.6 -0.2 -0.2 -1.0 0.8 0.9 -0.3 0.6 0.7 0.7 1.1 0.6 -0.3 0.8 -0.7 -1.0 -1.8 0.9 -0.1 0.9 0.5 -0.0 0.7 0.6 0.6 0.3 0.5 0.7 1.0 0.6 0.8 0.3
Pulse wave reflection index 0.3 0.3 3.5 0.6 -0.3 1.3 0.5 0.1 1.0 0.8 -0.1 0.4 -0.2 0.9 0.3 0.1 -0.1 0.4 0.1 -0.0 -1.9 -0.4 0.5 -0.5 0.5 -0.1 -0.6 0.1 -0.2 -0.4 0.1 -0.3 0.1 0.6 -0.5 -0.5 0.3 -0.3 0.7
Ever highly irritable/argumentative for 2 days 1.1 1.3 4.5 1.3 0.5 1.5 1.1 1.0 0.6 1.1 2.1 1.2 0.8 1.3 0.9 1.1 1.1 0.5 1.1 1.8 0.7 -0.4 1.1 1.2 0.5 1.9 1.1 1.0 1.1 0.8 1.2 0.8 1.1 1.1 1.0 1.1 1.1 1.1 1.3
Loud music exposure frequency 0.8 0.9 4.1 -1.1 -0.7 -0.5 -1.2 -0.9 -1.5 -0.4 -0.4 -0.6 -1.3 0.3 -0.9 -1.0 -0.9 -1.6 -1.0 -1.0 -0.3 1.0 -0.6 -0.6 -1.1 -0.3 -0.8 -0.9 -0.9 -1.0 -0.8 -0.8 -0.3 -0.8 -1.0 -2.0 -0.9 -0.8 -0.9
Qualifications: O levels/GCSEs or equivalent 0.8 1.2 3.5 -1.6 -1.4 -0.3 -0.8 -1.1 -0.9 -0.8 -1.0 -1.2 -0.6 -0.9 -1.1 -1.1 -0.8 -0.2 -1.2 -1.5 -1.0 0.9 0.1 -1.9 -0.5 -1.2 -1.3 -1.3 -1.3 -0.9 -0.9 -1.2 -0.9 -1.0 -1.4 -1.6 -1.1 -1.3 -1.0
Mouth/teeth dental problems: Bleeding gums 0.3 0.4 2.6 -0.5 -0.6 0.7 -0.3 -0.4 -0.9 0.4 1.0 -0.2 -0.9 0.5 -0.2 -0.6 -0.2 -1.6 -0.1 -0.0 -0.3 -0.1 -0.1 -0.9 -1.5 0.5 -0.5 -0.2 0.6 -0.6 -0.3 -0.2 -0.0 -0.2 -0.3 -0.1 -0.1 -0.7 -0.5
Blood clot in the leg (DVT) 3.0 3.8 6.3 -2.1 -2.3 -1.8 -2.3 -2.0 -1.7 -2.4 -1.2 -2.1 -1.9 -1.0 -2.1 -2.1 -1.9 -1.3 -2.0 -2.4 -1.6 2.1 -1.3 -2.5 -1.4 -1.6 -2.2 -2.1 -1.8 -2.0 -1.9 -2.0 -1.9 -2.0 -2.0 -2.3 -1.9 -2.1 -1.8
Medication: Paracetamol 1.6 2.6 6.9 1.9 1.7 2.4 1.7 1.7 1.6 2.1 0.7 1.7 1.3 2.2 1.6 1.8 1.4 0.1 1.5 1.7 0.7 -1.6 1.8 -0.8 2.6 1.5 1.2 1.5 0.7 1.5 1.4 1.3 1.6 2.0 1.3 1.3 1.5 1.6 2.1
Headache pain in last month 3.1 5.3 11.2 2.4 2.3 2.8 2.0 2.6 2.1 3.0 2.7 2.8 1.7 3.4 2.4 2.6 2.8 1.4 2.3 2.2 0.8 -2.0 3.0 0.3 2.7 1.8 1.8 2.5 1.8 2.0 2.4 1.9 2.5 2.7 1.8 0.6 2.4 2.2 2.7
Medication for cholesterol, blood pressure or diabetes 0.4 0.7 3.1 -1.3 0.2 -1.5 -0.9 -0.8 -1.1 -1.1 -0.9 -0.6 -0.4 -0.9 -0.8 -0.8 -0.9 -0.7 -0.9 -0.7 0.4 0.7 -1.7 -0.5 -1.0 -0.1 -0.3 -0.8 -0.2 -0.5 -0.6 -0.3 -1.0 -1.1 -0.3 -0.7 -0.9 -0.6 -1.2
Glaucoma (self-reported) 0.2 0.3 1.6 0.4 -0.8 1.1 -0.0 0.1 -0.3 -0.3 0.8 -0.2 -0.6 0.8 -0.1 0.1 -0.1 -0.4 -0.3 0.5 0.2 0.3 0.9 0.0 0.4 1.3 -0.1 -0.2 -0.9 -0.3 0.0 -0.1 -0.4 0.3 -0.0 -0.6 -0.1 0.4 0.7
Gout (self-reported) 0.3 0.5 1.6 -0.7 -1.0 0.6 -0.5 -0.7 0.0 -0.4 -0.8 -0.8 -0.4 -0.2 -0.4 -0.5 -0.6 -0.5 -0.6 -0.1 -1.1 0.4 0.8 -0.8 0.1 -0.9 -1.1 -0.4 -1.3 -0.8 -0.8 -0.8 -0.5 -0.2 -1.0 -1.1 -0.7 -0.7 0.1
Hypothyroidism/myxoedema (self-reported) 5.6 11.0 21.3 3.0 4.2 3.6 2.9 3.6 2.6 4.6 3.1 3.6 2.8 3.8 3.7 3.4 3.7 1.7 3.7 3.2 1.5 -3.4 4.2 2.8 2.5 2.6 2.8 3.8 3.0 3.6 3.8 3.0 4.3 3.4 3.1 2.4 3.8 2.6 3.0
Medication: Amlodipine 0.5 0.7 2.9 0.4 -0.4 1.7 0.8 0.5 1.2 1.5 0.2 0.3 0.2 0.8 0.7 0.5 0.5 0.5 0.7 0.3 -1.4 -0.8 1.1 -0.9 0.8 -0.6 -0.3 0.7 1.1 0.2 0.3 -0.0 1.2 0.9 -0.2 1.4 0.8 -0.1 0.9
Medication: Ventolin 100micrograms inhaler 0.9 1.1 3.5 -0.8 -1.0 -1.3 -1.1 -0.9 -0.9 -1.0 -1.7 -1.0 -1.5 -1.3 -0.7 -1.0 -0.8 -1.4 -0.8 -1.8 0.5 0.4 -1.1 -0.2 -0.7 -1.5 -0.4 -0.6 -0.8 -1.1 -0.7 -0.2 -1.3 -1.0 -0.5 -1.9 -0.9 -0.7 -1.5
Birth weight 2.0 4.4 11.4 -2.4 -2.3 -1.9 -1.6 -2.0 -2.2 -3.3 -1.3 -2.4 -1.6 -1.1 -1.9 -2.1 -1.9 -0.2 -2.1 -2.8 -2.0 1.7 -2.4 -2.5 -2.5 -1.7 -2.3 -2.0 -2.2 -1.8 -1.8 -1.9 -1.9 -2.0 -2.2 -3.4 -1.8 -2.3 -1.9
Chronic bronchitis/emphysema (mother) 0.4 0.5 1.3 0.9 0.9 0.3 1.0 0.9 -0.1 0.6 0.1 0.5 0.7 0.0 0.7 0.9 1.0 0.1 0.7 0.1 1.0 -1.0 0.4 0.3 0.6 -0.5 0.9 0.5 -0.5 1.1 0.9 0.8 0.5 0.8 0.7 0.6 0.6 0.9 0.8
High blood pressure (siblings) 0.4 0.6 3.9 0.4 -0.3 2.0 0.1 0.3 1.2 1.4 1.1 0.2 0.4 1.1 0.4 0.3 0.3 -0.1 0.5 0.6 -1.1 -0.0 1.7 -0.8 -0.1 0.0 -0.7 0.4 0.9 0.0 0.2 -0.4 1.1 0.7 -0.6 -0.1 0.4 -0.3 0.9
Forced vital capacity (FVC), Best measure 0.6 2.3 10.4 -1.7 -1.2 -2.1 -0.6 -1.2 -1.5 -2.7 -2.0 -1.3 0.1 -1.7 -1.4 -1.2 -1.4 1.1 -1.7 -2.0 -0.2 0.9 -2.6 -3.2 -0.8 -1.4 -0.8 -1.7 -1.6 -0.8 -1.3 -0.8 -1.8 -1.4 -0.9 -1.5 -1.4 -0.8 -1.4
Body fat percentage 0.3 1.3 4.4 0.6 0.9 2.1 1.2 1.2 1.8 1.3 0.7 1.1 1.3 1.6 1.3 1.1 1.0 2.1 1.3 0.3 -1.3 -1.1 0.6 0.7 0.3 -0.4 0.4 1.3 0.5 0.9 1.0 0.4 1.8 1.5 0.3 1.0 1.3 0.7 1.4
Leg fat percentage (right) 0.4 1.4 3.7 1.1 0.9 1.9 1.4 1.4 1.7 1.8 0.3 1.3 1.0 1.5 1.5 1.3 1.1 1.0 1.6 0.5 -0.8 -1.1 0.4 1.4 0.4 -0.7 0.7 1.6 0.5 1.1 1.2 0.6 1.6 1.4 0.5 1.2 1.4 0.8 1.4
Arm fat-free mass (right) 1.5 7.7 12.5 -3.0 -3.5 -2.1 -2.5 -2.9 -2.2 -3.4 -3.1 -3.2 -2.3 -2.7 -2.9 -2.8 -3.1 -1.4 -2.8 -3.5 -2.5 2.7 -3.3 -2.8 -2.5 -3.5 -2.8 -2.8 -1.7 -2.6 -3.1 -3.0 -2.7 -2.6 -3.1 -1.5 -2.8 -2.7 -2.4
Exposure to tobacco smoke outside home 0.1 0.2 1.2 0.2 0.1 0.2 0.4 0.2 0.1 -0.1 0.9 0.4 -0.1 0.7 0.1 0.2 0.1 0.6 0.1 0.3 0.4 -0.1 -0.6 -0.2 0.5 1.1 0.5 0.0 -0.5 0.1 0.4 0.4 -0.1 0.3 0.5 0.0 0.2 0.7 0.5
Comparative body size at age 10 0.5 1.4 10.0 -1.1 -0.9 -0.5 -0.5 -0.7 0.3 -1.6 -2.5 -1.2 -0.6 -1.4 -0.7 -0.5 -0.7 -0.5 -0.7 -2.0 -1.8 0.7 -1.6 -1.0 -0.2 -3.2 -1.0 -0.7 -1.7 -0.5 -0.6 -1.1 -1.1 -0.6 -1.3 -0.3 -0.8 -0.8 -0.3
Number of full brothers 0.2 0.3 2.1 0.4 -0.1 0.4 -0.1 0.3 -0.3 1.1 1.0 0.5 -0.0 0.6 0.1 0.3 0.3 -0.5 0.2 0.7 0.7 0.3 0.9 -0.2 1.5 0.2 0.6 0.2 -0.1 -0.1 0.1 0.2 0.1 0.3 0.2 0.3 -0.0 0.6 0.3
Worry too long after embarrassment 0.4 0.6 2.2 -0.6 -0.9 -0.4 -0.8 -0.8 -1.4 -0.6 -0.4 -0.9 -1.2 -0.3 -0.7 -1.0 -1.0 -1.5 -0.5 -0.5 -0.7 0.3 0.0 -0.0 -1.3 -0.3 -0.7 -0.7 0.4 -0.7 -0.8 -0.7 -0.1 -0.9 -0.8 0.1 -0.6 -1.1 -1.5
Seen a psychiatrist for nerves, anxiety, tension or depression 1.1 1.4 2.7 1.3 1.1 1.6 1.1 1.2 0.7 1.2 0.9 1.3 1.1 1.4 1.3 1.1 1.2 1.0 1.3 1.3 0.9 -1.4 1.4 0.5 0.8 1.6 1.1 1.3 1.1 1.1 1.0 1.1 1.4 1.3 1.1 0.8 1.4 1.0 0.9
Wheeze or whistling in the chest in last year 1.3 2.3 7.7 1.5 1.6 2.4 1.3 1.4 1.4 2.3 2.4 1.4 0.9 1.9 1.3 1.6 1.7 0.9 1.4 1.4 0.4 -0.9 2.3 0.8 2.8 1.1 0.9 1.4 1.3 1.2 1.2 0.7 1.4 1.7 1.0 1.0 1.4 1.4 2.0
Number of children fathered 2.1 2.4 9.2 1.9 1.1 0.7 1.5 1.6 0.9 2.2 0.9 1.9 1.4 0.7 1.5 1.8 1.6 0.9 1.5 1.6 1.9 -1.5 1.9 0.5 3.0 0.6 1.7 1.5 1.1 1.4 1.3 1.5 0.9 1.8 1.6 1.7 1.4 1.9 1.9
Reason for reducing amount of alcohol drunk: Health precaution 0.7 0.8 3.2 -0.9 -0.2 -0.4 -0.8 -0.5 -0.4 -0.4 -1.8 -0.8 -0.7 -1.2 -0.8 -0.6 -1.0 -1.3 -0.8 -1.0 -1.1 0.8 -0.0 -0.6 -0.6 -1.0 -1.1 -0.7 -1.6 -0.4 -0.4 -0.9 -0.7 -0.7 -1.0 -1.7 -0.8 -1.0 -0.3
Age at first live birth 5.8 10.3 16.3 -3.1 -3.3 -3.6 -3.3 -3.4 -3.3 -4.0 -1.3 -3.8 -3.3 -3.5 -3.7 -3.3 -3.1 -3.3 -3.6 -3.4 -0.8 3.7 -3.2 -1.2 -2.9 -2.4 -2.9 -3.6 -2.4 -3.3 -3.1 -3.1 -4.0 -3.7 -3.0 -3.0 -3.6 -3.1 -3.3
Pulse wave peak to peak time 0.9 1.1 3.5 -1.3 -1.0 -1.9 -1.3 -1.0 -1.3 -1.7 0.0 -1.1 -0.7 -1.5 -1.1 -1.1 -0.7 0.2 -1.1 -1.1 1.5 1.1 -0.8 0.4 -0.4 -0.2 -0.3 -1.1 -0.8 -1.0 -0.9 -0.3 -1.2 -1.4 -0.3 -1.0 -1.1 -0.4 -1.5
Health satisfaction 0.2 0.2 0.8 0.9 0.3 0.2 0.3 0.5 0.1 0.3 0.6 0.3 -0.4 0.6 0.4 0.5 0.6 -0.9 0.5 0.5 0.7 -0.1 -0.2 0.2 -0.5 0.8 0.5 0.5 -0.0 0.2 0.4 0.4 0.2 0.3 0.6 0.3 0.4 0.6 0.4
Shortness of breath walking on level ground 0.2 0.2 2.7 0.4 0.7 0.3 0.0 0.3 0.2 0.4 1.7 0.3 0.2 0.2 0.1 0.2 0.3 -0.2 0.2 0.4 0.8 -0.1 0.7 0.9 0.3 0.8 0.2 0.2 -0.0 0.2 0.2 0.4 0.3 0.3 0.3 -0.2 0.1 0.3 0.3
Qualifications: College or University degree 4.6 14.6 22.3 -3.8 -3.7 -4.1 -4.0 -3.8 -3.5 -4.7 -4.1 -4.4 -3.7 -4.0 -4.0 -3.8 -4.0 -3.1 -3.9 -4.4 -2.2 4.1 -4.3 -1.1 -4.0 -3.7 -3.4 -3.9 -3.5 -3.5 -3.5 -3.6 -4.3 -4.3 -3.5 -4.0 -3.9 -3.8 -4.0
Eye problems/disorders: None of the above 0.1 0.2 1.6 -0.3 0.2 0.6 0.4 -0.0 0.2 0.2 -0.8 0.2 0.3 0.3 0.1 -0.1 -0.5 0.6 0.2 0.0 -1.3 -0.4 -0.3 -0.1 -0.2 0.4 -0.6 0.0 0.6 0.0 0.2 -0.3 0.6 0.2 -0.4 0.4 0.3 -0.5 0.2
Mouth/teeth dental problems: Loose teeth 0.4 0.5 2.5 -0.4 -0.7 -1.1 -1.0 -0.6 -0.8 0.0 -1.0 -0.5 -0.8 -1.2 -0.7 -0.6 -0.7 -1.6 -0.6 -0.6 0.0 0.6 0.2 0.8 0.9 -0.7 -0.3 -0.5 -1.0 -0.3 -0.6 -0.5 -0.3 -0.7 -0.4 0.1 -0.7 -0.5 -0.9
Emphysema/chronic bronchitis 0.8 0.9 3.6 -0.7 -0.6 1.2 -0.6 -0.9 -0.8 -0.1 0.6 -0.9 -1.3 0.7 -0.9 -0.9 -0.6 -0.7 -0.8 -0.8 -1.5 1.2 -0.1 -1.0 -0.5 -0.4 -1.8 -0.8 -0.2 -0.8 -0.9 -1.9 0.0 -0.4 -1.7 -0.9 -0.6 -1.4 0.1
Medication for pain relief, constipation, heartburn 0.4 0.7 5.9 -0.7 -0.9 -2.4 -0.8 -0.5 -1.3 -0.9 0.3 -0.3 -0.2 -1.6 -0.7 -0.6 -0.3 1.1 -0.5 -1.0 1.3 0.5 -0.8 -0.4 -0.8 -0.3 0.5 -0.6 -0.2 -0.7 -0.5 0.3 -1.2 -0.8 0.3 -0.9 -0.6 0.2 -1.1
Neck or shoulder pain in last month 0.5 0.7 3.5 -0.6 -0.6 -0.6 -0.8 -0.8 -1.7 -0.5 0.1 -0.8 -1.1 0.6 -0.8 -0.7 -0.8 -1.1 -0.9 -0.4 -0.3 0.8 0.1 -1.9 -0.1 0.8 -0.9 -0.8 -0.5 -0.5 -0.8 -0.6 -0.4 -0.7 -0.6 -1.8 -0.7 -0.7 -0.6
Medication: Blood pressure 0.5 0.8 6.6 0.6 -0.5 2.1 0.4 0.3 1.7 1.2 -0.1 0.0 0.2 0.4 0.2 0.4 0.1 0.0 0.4 0.2 -2.6 -0.0 1.5 0.1 1.2 -0.7 -0.9 0.2 0.2 0.1 0.0 -1.0 1.0 0.9 -0.9 1.3 0.5 -0.3 1.3
Angina (self-reported) 0.7 0.9 6.1 0.6 0.4 2.5 0.8 0.4 1.1 0.7 2.1 0.5 0.4 1.6 0.5 0.4 0.7 0.5 0.5 1.1 -0.5 -0.5 1.3 0.2 -0.2 1.7 0.1 0.5 0.5 0.3 0.4 -0.0 1.3 1.1 0.1 1.7 0.8 0.4 1.1
Migraine (self-reported) 0.1 0.1 0.7 0.1 0.5 0.4 0.2 -0.1 0.1 0.8 -0.5 0.3 0.4 0.1 -0.0 -0.0 0.0 -0.3 -0.2 -0.5 -0.2 -0.1 -0.2 -0.8 0.8 -0.5 -0.4 -0.2 -0.5 -0.1 -0.1 -0.3 -0.0 0.2 -0.4 -0.2 0.0 -0.1 0.4
Medication: Ibuprofen 0.3 0.4 2.4 0.1 1.0 1.5 0.8 0.5 0.5 1.0 -0.4 0.4 0.5 0.9 0.5 0.4 0.5 -0.4 0.4 0.6 -0.5 -0.5 0.8 -0.4 1.5 -0.0 -0.4 0.4 0.0 0.7 0.6 0.0 0.9 0.5 -0.1 0.2 0.5 -0.2 0.8
Medication: Allopurinol 0.6 0.8 3.0 -0.7 -1.4 0.7 -0.8 -0.9 -0.6 -0.6 -0.9 -1.0 -0.9 0.4 -0.7 -0.9 -1.0 -0.7 -0.8 -0.4 -1.7 0.8 0.8 -0.6 -0.5 -0.1 -1.5 -0.6 -1.0 -1.1 -1.0 -1.1 -0.4 -0.4 -1.2 -1.5 -0.7 -1.2 -0.2
Medication: Omeprazole 4.6 5.5 8.8 2.7 2.6 2.7 2.6 2.6 2.6 2.5 2.2 2.6 2.0 2.0 2.6 2.7 2.7 0.9 2.7 2.5 0.9 -2.2 1.9 3.0 1.9 1.6 2.2 2.7 2.0 2.3 2.5 2.1 2.4 2.6 2.1 1.7 2.6 2.4 2.6
Medication: Seretide 50 evohaler 0.8 0.9 2.8 -0.9 -0.2 -0.8 -1.1 -0.9 -0.4 -0.9 -1.1 -1.1 -0.9 -0.5 -0.9 -0.9 -0.9 -0.5 -0.8 -1.5 -1.7 1.0 0.2 -0.5 -0.4 -1.5 -1.4 -0.9 -0.4 -0.4 -0.7 -1.3 -0.5 -0.9 -1.3 -1.5 -0.8 -1.3 -0.7
Mean time to correctly identify matches 1.1 2.1 4.8 -1.6 -1.2 -1.7 -2.0 -1.7 -1.8 -1.7 0.5 -1.5 -2.2 -0.7 -1.6 -1.8 -1.9 -0.4 -1.3 -1.5 -0.6 1.6 -1.3 -0.7 -1.6 -0.2 -1.4 -1.5 -0.4 -1.7 -1.4 -1.2 -1.4 -2.0 -1.1 -0.8 -1.4 -1.7 -2.0
Heart disease (mother) 1.9 2.3 5.9 1.6 1.4 2.4 2.1 1.4 2.3 1.6 -0.3 1.1 1.4 1.4 1.7 1.5 1.4 0.8 1.3 1.2 -1.5 -1.9 1.8 -0.3 1.2 0.6 0.3 1.5 1.3 1.9 1.3 0.9 2.4 2.0 0.6 1.4 1.7 0.8 2.2
Reproduciblity of spirometry measurement using ERS/ATS criteria 1.6 1.9 4.5 1.1 1.1 1.6 1.4 1.5 0.4 2.0 0.8 1.7 0.9 1.1 1.5 1.5 1.4 -0.9 1.6 1.6 0.9 -1.5 0.8 0.0 1.0 1.5 1.2 1.6 1.8 1.5 1.5 1.1 1.8 1.4 1.4 2.1 1.7 1.1 1.2
Whole body fat mass 0.1 0.4 2.7 -0.6 -0.4 1.1 0.2 0.0 0.7 0.1 -0.4 -0.1 0.3 0.4 0.2 0.0 -0.2 1.1 0.2 -0.9 -1.6 -0.2 -0.4 -0.5 -0.5 -1.5 -0.5 0.2 -0.4 -0.1 -0.1 -0.5 0.6 0.4 -0.7 0.2 0.2 -0.3 0.4
Leg fat mass (right) 0.1 0.3 2.5 -0.4 -0.6 0.9 0.3 0.0 0.5 0.2 -0.7 -0.1 0.0 0.3 0.2 0.0 -0.2 0.6 0.2 -0.9 -1.4 0.0 -0.7 0.2 -0.5 -1.6 -0.4 0.2 -0.3 -0.1 -0.1 -0.5 0.4 0.3 -0.6 0.4 0.1 -0.2 0.3
Arm predicted mass (right) 1.5 7.8 13.1 -3.0 -3.5 -2.2 -2.5 -2.9 -2.2 -3.4 -3.1 -3.2 -2.2 -2.8 -2.9 -2.9 -3.1 -1.3 -2.9 -3.6 -2.4 2.7 -3.2 -2.7 -2.5 -3.6 -2.9 -2.9 -1.9 -2.6 -3.1 -2.9 -2.7 -2.6 -3.1 -1.6 -2.8 -2.7 -2.4
Pulse rate, automated reading 0.6 2.0 10.4 -1.3 -1.2 -2.6 -1.5 -1.4 -2.2 -0.5 0.4 -1.3 -1.7 -2.1 -1.4 -1.5 -1.2 -3.2 -1.3 -1.4 1.1 1.1 -0.9 -0.6 -1.1 -1.1 -0.2 -1.3 -0.6 -1.0 -1.3 -0.5 -1.7 -1.5 -0.5 -1.0 -1.4 -0.7 -1.8
Alcohol intake frequency. 2.6 6.0 9.7 3.0 2.8 1.9 2.5 2.8 2.6 2.6 1.7 2.5 2.5 1.8 3.0 2.7 2.8 0.9 2.9 1.9 2.2 -3.1 1.8 2.0 0.7 0.9 2.8 3.0 2.0 2.9 2.8 3.0 2.7 2.5 2.8 2.4 2.8 2.5 1.9
Comparative height size at age 10 0.4 2.2 7.1 -2.1 -1.4 -0.9 -0.8 -1.4 -1.3 -2.1 -2.3 -1.3 -0.7 -1.8 -1.4 -1.4 -1.5 0.6 -1.6 -1.9 -0.8 0.9 -1.8 -2.7 -0.7 -1.2 -1.3 -1.6 -1.7 -1.5 -1.5 -1.2 -1.5 -1.0 -1.5 -1.2 -1.4 -1.1 -1.1
Number of full sisters 0.3 0.3 1.1 0.4 0.2 -0.4 0.8 0.5 -0.1 1.1 0.3 0.9 -0.3 -0.0 0.7 0.5 0.4 -0.1 0.7 0.6 0.9 -0.9 -0.3 0.7 -0.3 0.1 1.0 0.8 0.8 0.1 0.4 0.9 0.0 0.4 0.9 0.5 0.5 0.6 -0.1
Suffer from ‘nerves’ 0.4 0.6 2.9 0.9 0.5 0.5 0.8 0.4 0.7 1.5 0.1 0.7 -0.0 0.1 0.7 0.5 0.4 0.2 0.5 0.8 1.1 -1.1 1.0 0.4 1.7 1.2 0.9 0.7 0.8 -0.1 0.3 1.0 0.1 0.8 0.9 1.2 0.6 1.0 0.4
Overall health rating 0.2 0.4 2.1 0.9 0.0 1.4 0.7 0.4 0.4 1.0 0.9 0.4 -1.0 1.3 0.7 0.3 0.5 -1.3 0.5 0.2 -0.2 -0.7 0.7 0.5 -0.0 0.7 0.2 0.6 -0.3 -0.2 0.3 0.5 0.5 0.8 0.2 -0.3 0.6 0.3 0.5
Chest pain or discomfort 1.2 1.7 4.3 -1.3 -1.2 0.7 -1.4 -1.6 -1.1 -0.7 0.8 -1.5 -1.8 0.2 -1.6 -1.5 -1.2 -1.7 -1.4 -0.3 -1.1 1.8 0.3 -1.8 -0.5 -0.1 -2.0 -1.6 -0.6 -1.3 -1.7 -2.1 -0.6 -1.2 -1.9 -0.5 -1.5 -1.6 -0.9
Had major operations 1.0 1.2 2.8 0.8 0.7 1.5 0.4 0.9 0.8 0.9 1.6 1.0 0.4 1.5 1.1 0.7 1.2 1.4 1.2 1.2 0.4 -1.2 1.5 0.9 -0.1 1.6 0.8 1.2 1.7 0.9 1.1 1.0 1.7 0.8 1.1 1.0 1.4 0.5 0.2
Age at last live birth 3.7 5.3 11.2 -2.0 -2.7 -2.9 -2.2 -2.5 -2.8 -2.7 -0.8 -2.6 -2.8 -2.2 -2.6 -2.3 -2.2 -2.2 -2.6 -2.6 -0.2 2.8 -1.8 -1.1 -1.1 -1.2 -1.9 -2.6 -2.1 -2.8 -2.4 -2.2 -3.4 -2.5 -2.0 -2.2 -2.7 -1.9 -2.1
Family relationship satisfaction 0.4 0.5 3.1 0.8 0.5 0.9 0.6 0.5 0.1 1.0 0.9 0.6 -0.1 0.5 0.6 0.5 0.6 -1.0 0.5 0.7 0.7 -0.8 1.8 1.2 0.0 1.0 0.7 0.6 0.4 0.4 0.4 0.8 0.6 0.8 0.6 0.4 0.6 0.7 0.6
Leg pain on walking 0.2 0.3 1.8 0.1 0.6 0.0 -0.0 0.3 0.2 -0.8 0.2 -0.0 0.9 0.5 0.1 0.3 -0.1 1.2 0.3 0.8 0.1 0.2 -0.6 1.2 -0.6 1.3 0.4 0.2 0.0 0.7 0.3 0.2 0.6 0.0 0.5 -0.2 0.3 0.3 0.1
Qualifications: NVQ or HND or HNC or equivalent 0.4 0.5 2.0 0.6 0.5 1.4 0.9 0.6 1.2 0.6 0.6 0.5 0.7 1.1 0.5 0.7 0.6 0.7 0.3 0.9 -0.3 -0.3 0.8 0.0 1.1 1.4 0.2 0.4 0.8 0.5 0.4 0.2 0.6 0.8 0.4 0.6 0.5 0.6 1.2
Commuting to job workplace: Car/motor vehicle 3.1 3.6 7.1 2.2 1.4 2.5 2.7 2.1 2.3 2.6 1.5 2.3 2.0 2.6 2.1 2.1 2.2 2.1 1.8 1.5 -0.4 -2.0 1.7 -0.1 2.0 1.1 1.2 2.0 0.8 1.5 1.9 1.3 1.8 2.5 1.2 1.3 2.1 1.6 2.5
Illness, injury, bereavement, stress in last 2 years 0.3 0.3 3.4 -0.6 0.2 -0.1 -0.4 -0.0 -0.3 -0.3 -0.4 -0.2 -0.2 -0.7 0.1 -0.2 -0.2 -0.1 0.2 -0.5 -0.2 -0.2 -0.3 1.9 -1.6 -1.2 0.0 0.1 -0.2 -0.2 0.0 0.1 0.0 -0.4 -0.1 0.4 0.0 -0.5 -0.9
Medication: Aspirin 0.3 0.3 2.4 0.3 0.3 1.5 0.4 0.1 1.0 0.1 0.1 -0.1 0.3 1.2 0.2 0.1 -0.0 0.4 0.0 0.5 -1.0 -0.1 0.3 0.8 -0.3 0.0 -0.5 0.1 0.3 0.5 0.1 -0.7 1.1 0.2 -0.5 1.2 0.4 -0.4 0.5
Supplements: Vitamin C 0.7 0.8 3.0 -0.6 0.2 -1.7 -1.2 -0.8 -0.8 -1.0 -1.2 -0.8 -0.2 -1.0 -0.9 -0.9 -0.8 -0.2 -0.8 -1.5 -0.3 0.8 -0.8 -0.3 -0.7 -0.7 -1.0 -0.9 -0.7 -0.3 -0.5 -0.7 -0.5 -1.1 -0.7 -1.5 -0.8 -1.1 -1.0
Knee pain experienced in last month 1.8 2.9 7.8 -1.7 -1.3 -2.8 -2.2 -1.9 -2.4 -2.5 -0.2 -1.4 -2.2 -1.6 -1.8 -1.9 -1.8 -1.8 -1.7 -1.5 0.4 1.8 -2.3 -0.9 -1.1 -0.7 -0.9 -1.7 -1.6 -1.8 -1.7 -1.1 -1.9 -1.9 -1.0 -1.6 -1.7 -1.1 -1.9
Hypertension (Self-reported) 1.0 2.9 14.1 2.2 0.8 3.8 1.7 1.6 2.9 2.1 1.1 1.4 1.2 1.9 1.6 1.7 1.5 0.5 1.8 1.5 -1.3 -1.4 2.0 1.2 1.2 0.2 0.4 1.6 1.5 1.4 1.3 0.4 2.2 2.2 0.4 2.1 1.8 0.9 2.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 2.4 2.8 5.6 2.0 1.4 0.7 1.7 1.8 0.7 1.8 2.4 2.0 1.2 1.8 1.8 1.8 1.9 0.3 1.8 1.7 2.0 -1.6 1.3 1.1 1.8 1.3 2.1 1.9 1.1 1.7 1.8 2.0 1.5 1.6 2.0 0.3 1.7 2.0 1.4
Illnesses of father: Heart disease 2.5 3.4 7.7 2.8 1.5 1.2 2.2 2.0 2.6 1.5 1.0 1.9 1.9 0.7 1.9 2.3 2.2 1.2 1.9 1.5 1.4 -1.7 1.1 1.7 2.2 0.4 2.1 2.0 1.4 1.7 1.7 1.8 1.2 2.3 1.8 2.2 1.7 2.5 2.6
Illnesses of siblings: Diabetes 0.2 0.2 1.4 -0.2 -0.6 -0.3 -0.1 -0.3 -0.2 0.3 -0.3 -0.1 -0.2 -0.8 -0.2 -0.1 -0.3 -0.2 -0.2 -0.1 0.9 0.2 -0.1 -0.7 1.2 -1.0 0.2 -0.2 -0.4 -0.5 -0.5 0.0 -0.9 -0.0 -0.2 -0.3 -0.5 0.4 0.1
Smoking status: Previous 0.3 0.4 1.2 -0.8 -0.7 -0.3 -0.6 -1.0 -1.0 -1.0 0.3 -0.5 -0.7 -0.7 -0.8 -0.8 -0.5 0.4 -0.9 -0.6 0.5 0.8 -0.5 -0.4 -0.4 0.5 -0.2 -0.8 -0.5 -1.1 -1.0 -0.5 -0.7 -0.5 -0.5 -0.3 -0.7 -0.0 -0.4
Forced expiratory volume in 1-second (FEV1), predicted 0.2 0.4 3.7 -0.8 -0.4 -0.7 0.1 -0.4 -0.3 -1.0 -0.1 -0.4 0.7 -0.5 -0.5 -0.3 -0.3 1.4 -0.8 -0.5 0.1 -0.0 -0.0 -1.9 0.9 0.6 -0.1 -0.7 -0.6 -0.3 -0.4 0.0 -0.5 -0.1 -0.1 -1.2 -0.5 0.3 -0.0
Whole body fat-free mass 1.5 8.3 14.5 -3.3 -3.8 -2.3 -2.5 -3.1 -2.6 -3.5 -3.0 -3.3 -2.4 -2.8 -3.0 -3.0 -3.2 -1.4 -3.0 -3.6 -2.0 2.6 -3.3 -3.1 -2.7 -3.3 -2.8 -3.0 -1.9 -2.8 -3.2 -2.8 -2.9 -2.8 -3.0 -1.6 -2.9 -2.8 -2.7
Leg fat-free mass (right) 1.8 9.4 15.1 -3.8 -3.9 -2.3 -2.8 -3.4 -2.8 -3.8 -2.7 -3.6 -2.6 -2.7 -3.4 -3.3 -3.6 -1.2 -3.3 -3.7 -2.4 3.0 -3.3 -3.2 -2.6 -2.9 -3.1 -3.4 -2.0 -3.1 -3.5 -3.1 -3.0 -2.9 -3.3 -2.1 -3.2 -2.9 -2.8
Arm fat percentage (left) 0.3 1.1 4.4 0.3 0.6 2.1 1.0 1.0 1.6 1.3 0.6 1.0 0.9 1.6 1.2 0.9 0.9 1.6 1.2 0.2 -1.3 -1.1 0.8 0.7 0.1 -0.3 0.4 1.2 0.5 0.7 0.8 0.4 1.7 1.4 0.2 1.0 1.2 0.6 1.2
Average weekly red wine intake 0.9 1.3 5.1 -0.6 -1.3 -1.1 -0.9 -0.9 -0.7 -1.5 -1.5 -0.9 -1.0 -1.6 -1.0 -0.8 -0.7 -0.5 -0.8 -1.7 -0.3 1.5 -1.5 -0.2 -0.8 -2.3 -0.8 -1.0 -1.9 -1.2 -0.8 -1.2 -1.6 -0.9 -1.2 -0.9 -1.1 -0.8 -0.5
Handedness (chirality/laterality): Left-handed 1.2 1.4 2.7 -1.5 -1.5 -0.2 -1.1 -1.4 -1.4 -1.2 0.4 -1.2 -1.5 -0.0 -1.5 -1.3 -1.3 -0.8 -1.6 -0.4 -1.0 1.6 -0.8 -1.4 -0.1 1.2 -1.5 -1.5 0.2 -1.4 -1.5 -1.4 -1.0 -0.8 -1.3 -1.3 -1.4 -1.1 -0.3
Mood swings 5.9 10.6 20.5 3.1 3.3 4.3 3.5 3.5 2.8 4.5 2.6 3.7 3.1 3.5 3.7 3.5 3.5 1.6 3.4 3.4 1.1 -3.5 4.3 1.3 3.8 2.8 2.4 3.7 2.5 3.3 3.4 2.8 3.7 3.8 2.7 1.5 3.6 2.8 3.8
Loneliness, isolation 0.9 1.3 3.4 1.4 1.2 1.8 1.2 1.0 1.1 1.3 1.2 1.0 0.8 1.0 1.2 1.0 0.9 0.5 1.1 1.3 0.3 -1.4 1.9 0.8 1.0 0.5 0.8 1.1 1.8 1.1 0.8 0.9 1.1 1.2 0.9 1.0 1.1 1.0 0.9
Long-standing illness, disability or infirmity 0.3 0.4 1.7 1.0 -0.0 1.3 0.6 0.6 0.1 0.6 0.8 0.3 0.1 1.0 0.7 0.6 0.7 -0.3 0.7 0.5 0.5 -0.4 0.7 1.3 -0.1 1.0 0.3 0.8 0.3 0.4 0.6 0.2 0.8 0.7 0.4 0.4 0.8 0.4 0.7
Ever had bowel cancer screening 0.2 0.2 1.1 -0.2 -0.3 1.0 -0.5 -0.0 -0.6 0.5 -0.6 -0.3 -0.9 0.5 0.0 -0.3 -0.4 -0.8 0.2 -0.7 -0.9 -0.3 0.6 -0.1 -0.2 0.3 -0.7 0.1 0.6 -0.1 0.1 -0.2 0.6 -0.1 -0.3 -0.1 0.3 -0.9 -0.5
Diabetes diagnosed by doctor 1.4 2.3 5.8 -1.4 -1.4 0.4 -1.1 -1.8 0.2 -1.0 -0.7 -1.8 -1.9 -1.5 -1.8 -1.6 -1.4 -1.3 -1.9 -1.4 -1.5 1.8 -0.8 0.7 -0.8 -1.5 -1.7 -1.8 -2.4 -2.3 -1.8 -2.0 -2.0 -1.1 -2.1 -1.1 -1.7 -1.4 -0.7
Ever had stillbirth, spontaneous miscarriage or termination 1.9 2.1 5.0 1.7 1.3 0.8 1.5 1.5 1.4 1.9 0.4 1.6 1.0 0.1 1.7 1.4 1.7 -0.3 1.9 0.8 1.5 -2.2 1.6 2.0 0.1 0.0 1.8 1.6 1.1 1.3 1.5 1.7 1.5 1.4 1.5 2.0 1.6 1.3 0.7
Friendships satisfaction 1.2 1.5 3.4 1.5 1.1 1.3 1.1 1.4 0.7 1.2 1.2 1.5 0.6 1.6 1.3 1.3 1.1 0.1 1.1 1.7 0.8 -1.2 1.5 1.0 0.4 1.8 1.4 1.4 0.6 0.9 1.3 1.5 1.2 1.4 1.4 -0.2 1.3 1.5 1.2
Qualifications: nursing, teaching 1.5 2.3 7.3 -1.1 -1.5 -2.7 -1.6 -1.3 -2.5 -2.3 -1.4 -1.8 -1.2 -1.8 -1.4 -1.5 -1.3 -1.7 -1.3 -2.1 0.2 0.9 -1.2 -0.5 -1.9 -1.2 -0.9 -1.5 -0.5 -0.7 -1.0 -0.9 -1.6 -2.0 -0.7 -1.3 -1.3 -1.4 -2.2
Commuting to job workplace: Walk 4.3 4.6 12.2 -2.2 -1.1 -1.5 -2.4 -2.3 -0.7 -2.0 -3.5 -2.7 -2.3 -2.2 -2.2 -2.3 -2.6 -2.4 -2.2 -2.5 -2.1 2.1 -1.4 -0.7 -1.5 -2.4 -2.4 -2.2 -1.3 -1.7 -2.2 -2.2 -1.8 -2.4 -2.4 -1.8 -2.3 -2.4 -2.3
Eye problems/disorders: Cataract 0.3 0.3 1.2 -0.2 -0.6 -0.7 -0.7 -0.6 -0.1 -0.7 0.4 -0.6 -1.1 -0.5 -0.5 -0.6 -0.2 -1.1 -0.6 -0.6 0.0 0.3 -0.4 -0.3 -0.9 -0.3 -0.1 -0.4 -0.8 -0.8 -0.7 0.0 -0.7 -0.5 -0.2 -1.0 -0.6 -0.1 -0.6
Mouth/teeth dental problems: Mouth ulcers 1.3 2.1 4.8 1.3 1.8 -0.0 1.2 1.6 0.8 1.7 0.0 1.4 1.0 0.9 1.8 1.5 1.4 0.8 1.8 1.1 1.6 -2.1 1.2 1.9 0.5 0.7 2.1 1.8 1.4 1.6 1.7 2.2 1.5 1.3 2.0 1.6 1.6 1.6 0.5
Medication for cholesterol 2.3 3.4 5.7 -2.0 -1.9 -2.4 -1.7 -2.2 -1.3 -2.1 -1.1 -2.3 -1.5 -1.8 -2.1 -2.1 -2.2 -0.0 -2.3 -2.1 -1.9 2.0 -1.6 -1.7 -1.0 -1.2 -1.9 -2.2 -0.9 -2.1 -2.2 -2.0 -2.1 -2.0 -1.9 -1.2 -2.2 -1.8 -1.6
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.3 0.3 4.9 -0.0 1.0 0.5 0.2 0.1 0.4 0.1 -0.2 -0.2 0.4 -0.2 0.2 0.0 -0.2 0.0 -0.0 0.3 -0.2 -0.2 -0.2 2.2 -1.0 1.2 0.1 0.2 0.3 0.6 0.3 0.3 0.3 -0.2 0.4 -0.5 0.2 -0.2 -0.2
Back pain experienced in last month 1.5 2.2 7.2 1.1 1.5 0.9 1.0 1.2 0.0 2.1 2.7 1.6 1.0 1.6 1.3 1.2 1.5 -0.1 1.2 1.8 1.7 -1.2 1.8 0.2 1.4 2.7 1.4 1.3 2.0 1.4 1.3 1.4 1.8 1.3 1.6 1.7 1.4 1.3 1.2
Mineral and other dietary supplements 0.1 0.1 0.7 0.1 0.0 0.5 0.2 0.0 0.6 0.4 0.2 0.1 -0.1 0.3 0.1 0.1 0.1 -0.8 0.0 0.2 0.5 -0.2 -0.6 -0.8 0.3 -0.1 0.2 0.0 -0.6 -0.2 -0.0 0.2 -0.3 0.2 0.2 0.3 0.0 0.2 0.0
Breast cancer (self-reported) 0.1 0.1 1.2 -0.2 -1.1 -0.1 0.1 -0.5 -0.2 -0.6 0.2 -0.4 -0.0 -0.2 -0.3 -0.3 -0.2 -0.2 -0.3 0.4 0.0 0.2 -0.3 -0.6 -0.4 0.6 -0.3 -0.3 0.4 -0.5 -0.3 -0.3 -0.2 -0.2 -0.2 0.8 -0.3 -0.2 0.1
Asthma (self-reported) 0.3 0.7 4.8 0.0 0.4 -1.6 -0.1 0.1 -1.0 -0.5 -0.4 -0.2 -0.5 -1.7 0.2 0.1 0.2 -1.6 0.4 -0.3 2.2 -0.4 -0.7 1.5 -0.1 -1.1 1.0 0.3 0.2 0.3 0.2 1.0 -0.7 -0.4 0.9 0.1 -0.1 0.5 -0.9
Osteoporosis (self-reported) 0.9 1.1 3.9 0.7 1.1 1.4 1.1 1.0 1.1 0.8 0.8 0.5 0.6 1.3 1.2 0.8 0.9 0.5 1.2 1.0 0.1 -1.6 1.3 0.1 -0.9 0.9 0.7 1.1 2.0 1.5 1.1 1.0 1.6 0.7 1.0 1.8 1.3 0.3 0.1
Osteoarthritis (self-reported) 0.7 0.9 2.8 -0.3 -0.6 -1.0 -0.6 -0.7 -0.8 -1.7 -1.5 -1.0 -1.4 -1.5 -0.6 -0.7 -0.5 -0.9 -0.7 -1.2 0.3 0.5 -1.4 1.5 -1.5 -1.3 -0.4 -0.5 -0.9 -0.8 -0.5 -0.2 -1.1 -0.9 -0.4 -0.5 -0.7 -0.6 -1.0
Medication: Aspirin 0.2 0.3 2.4 -0.0 0.0 1.6 0.2 -0.1 0.9 0.1 -0.3 -0.2 0.1 1.0 -0.1 -0.1 -0.2 0.2 -0.1 0.4 -1.2 0.2 0.2 0.5 -0.3 -0.1 -0.8 -0.1 0.3 0.2 -0.1 -0.9 0.9 0.1 -0.8 1.3 0.2 -0.6 0.4
Medication: Gliclazide 0.9 1.0 3.5 -0.6 -0.6 1.0 -0.7 -1.0 1.1 0.1 -1.3 -1.0 -1.0 -1.0 -1.0 -0.8 -0.9 -1.3 -0.9 -1.1 -1.9 1.0 -0.4 0.8 -0.5 -1.4 -1.3 -1.0 -1.4 -1.1 -1.0 -1.4 -0.9 -0.5 -1.6 -0.8 -0.9 -0.9 -0.2
Illnesses of father: None of the above (group 1) 0.2 0.3 1.2 -1.1 -0.1 -1.0 -0.6 -0.3 -0.7 -0.7 -0.8 -0.1 0.3 -0.5 -0.4 -0.4 -0.8 0.7 -0.4 -0.1 0.3 0.3 -0.2 -0.6 -0.1 0.2 0.3 -0.3 -0.8 -0.2 -0.1 0.1 -0.6 -0.8 0.2 -0.6 -0.3 -0.2 -1.0
Smoking status: Current 0.5 0.7 2.7 0.8 0.8 1.6 0.8 0.8 1.2 1.1 0.7 1.0 0.6 1.1 0.9 0.8 0.9 0.5 0.9 1.0 -0.2 -0.8 0.7 -0.0 0.8 0.7 0.5 0.9 0.3 0.7 0.7 0.5 1.0 1.1 0.6 0.8 0.9 0.8 1.0
Forced expiratory volume in 1-second (FEV1), predicted percentage 1.2 2.6 6.9 1.8 1.6 0.1 1.7 1.8 0.9 0.9 0.5 2.1 2.6 0.9 1.6 1.8 1.7 2.6 1.5 1.2 2.6 -1.5 0.1 -0.4 2.3 0.6 2.1 1.6 0.9 1.7 1.7 1.9 1.0 1.5 2.0 1.1 1.5 2.0 1.4
Whole body water mass 1.5 8.7 15.2 -3.4 -3.9 -2.4 -2.6 -3.2 -2.7 -3.6 -3.0 -3.4 -2.5 -3.0 -3.1 -3.1 -3.2 -1.4 -3.1 -3.7 -2.0 2.7 -3.3 -3.2 -2.6 -3.3 -2.9 -3.1 -1.9 -2.9 -3.3 -2.9 -3.0 -2.9 -3.1 -1.7 -3.0 -2.8 -2.8
Leg predicted mass (right) 1.8 9.6 15.6 -3.9 -4.0 -2.4 -2.8 -3.4 -2.9 -3.8 -2.7 -3.7 -2.6 -2.7 -3.4 -3.3 -3.6 -1.3 -3.4 -3.7 -2.4 3.0 -3.4 -3.2 -2.6 -2.9 -3.1 -3.4 -2.0 -3.1 -3.6 -3.2 -3.1 -3.0 -3.3 -2.1 -3.3 -2.9 -2.8
Arm fat mass (left) 0.1 0.3 2.9 -0.6 -0.4 1.2 0.2 0.0 0.7 0.1 -0.5 -0.1 0.1 0.4 0.2 -0.0 -0.1 0.8 0.2 -0.8 -1.7 -0.2 -0.4 -0.3 -0.6 -1.4 -0.5 0.2 -0.3 -0.1 -0.1 -0.4 0.7 0.5 -0.7 0.3 0.3 -0.3 0.4
Number of self-reported non-cancer illnesses 0.8 1.4 4.3 1.5 0.8 2.0 1.2 1.4 0.8 1.3 0.4 1.2 0.0 1.1 1.5 1.3 1.4 -0.7 1.6 0.8 0.6 -1.5 1.4 2.1 -0.1 0.1 0.8 1.6 0.3 1.1 1.4 1.1 1.3 1.4 0.9 0.3 1.5 0.7 1.2
Average weekly champagne plus white wine intake 0.1 0.2 1.0 -0.2 0.7 0.7 0.3 -0.1 0.5 -0.2 0.3 -0.3 0.1 0.3 -0.2 -0.1 -0.0 0.5 -0.1 -0.0 -0.9 0.1 1.0 -1.0 -0.4 -0.0 -0.6 -0.3 0.4 0.3 0.2 -0.5 0.1 -0.2 -0.4 -0.1 -0.0 -0.5 -0.0
Miserableness 1.3 2.3 8.2 1.7 1.2 1.6 1.9 1.6 0.6 2.9 1.0 1.8 1.3 1.4 1.6 1.6 1.4 1.0 1.4 1.6 1.1 -1.6 2.1 0.4 2.5 1.0 1.4 1.6 0.8 1.5 1.4 1.5 1.2 1.5 1.4 0.4 1.5 1.4 1.3
Guilty feelings 0.7 1.0 3.2 -0.8 -0.8 -0.0 -0.8 -0.7 -1.3 0.2 -1.7 -0.9 -0.9 -0.9 -0.7 -0.9 -1.4 -1.8 -0.7 -0.9 -0.9 0.3 0.8 -0.5 -0.4 -1.0 -1.3 -0.7 -1.6 -0.4 -0.7 -0.7 -0.3 -1.0 -1.1 -1.8 -0.8 -1.4 -1.3
Wears glasses or contact lenses 0.8 1.0 2.6 -1.3 -0.6 -1.2 -1.2 -1.1 -1.2 -1.6 -0.5 -1.0 -1.2 -0.9 -1.0 -1.1 -1.1 -0.2 -0.9 -1.3 -0.7 1.0 -1.3 -0.0 -1.4 -0.4 -0.8 -1.0 -0.3 -1.0 -1.0 -1.0 -0.6 -1.1 -0.9 -0.4 -0.9 -0.8 -1.1
Ever taken oral contraceptive pill 0.6 0.7 2.7 0.1 0.8 1.7 0.5 0.4 1.0 1.0 1.2 0.7 0.6 0.4 0.6 0.5 0.9 1.6 0.5 0.6 -0.1 -0.6 1.4 1.1 1.5 -0.1 0.2 0.6 1.0 0.0 0.3 0.1 0.6 0.9 0.1 1.0 0.6 0.6 1.0
Hearing aid user 1.5 1.7 4.4 1.2 1.5 0.6 1.3 1.4 0.8 0.6 1.6 1.4 1.8 1.4 1.1 1.4 1.2 1.8 1.2 1.8 2.1 -0.7 1.3 -0.6 1.9 1.2 1.6 1.1 0.7 1.4 1.4 1.2 1.0 1.0 1.4 1.0 1.1 1.5 1.1
Mother’s age at death 0.9 1.1 4.4 -0.6 -0.7 -1.6 -1.1 -1.1 -1.3 -2.1 -1.0 -1.3 -1.3 -0.3 -1.3 -1.1 -1.3 -0.9 -1.4 -0.8 -0.4 1.3 -0.6 -0.6 -1.1 0.6 -0.6 -1.3 -0.6 -0.9 -1.0 -0.8 -1.0 -1.1 -0.7 -1.4 -1.2 -0.6 -0.9
Financial situation satisfaction 0.5 0.6 3.9 0.3 -1.4 -1.3 -0.3 -0.5 -1.4 -0.2 0.7 -0.2 -0.9 -0.7 -0.5 -0.3 0.0 -0.7 -0.4 -0.7 2.0 0.7 -0.8 -1.4 0.4 0.0 0.2 -0.5 -0.4 -0.9 -0.4 0.0 -1.1 -0.6 0.1 -0.2 -0.6 0.3 -0.4
Tinnitus: Yes, now most or all of the time 0.3 0.3 1.7 0.0 -0.5 -1.1 0.3 -0.2 -0.2 -0.5 -0.6 -0.1 0.2 -1.3 -0.3 -0.0 0.1 0.4 -0.4 -0.1 0.9 0.3 -1.2 -1.3 1.1 -0.2 0.1 -0.3 -0.2 0.1 -0.2 0.0 -0.7 -0.3 0.1 0.1 -0.4 0.2 0.1
Commuting to job workplace: Public transport 0.6 0.7 2.0 -0.9 -0.2 -0.7 -1.3 -0.8 -0.8 -0.9 -0.1 -1.0 -1.0 -1.2 -1.1 -0.8 -0.9 -1.4 -0.8 -0.8 0.2 1.2 -0.5 0.1 -0.8 -0.4 -0.8 -1.0 -0.8 -0.4 -0.7 -0.9 -0.7 -1.0 -0.7 -1.4 -0.9 -0.8 -0.7
Eye problems/disorders: Glaucoma 0.3 0.4 1.9 0.1 -1.2 0.3 -0.5 -0.3 -1.4 -0.5 1.0 -0.3 -0.8 0.3 -0.6 -0.2 -0.4 -0.9 -0.7 0.4 0.8 0.9 0.4 -0.6 0.7 1.0 -0.1 -0.5 -0.8 -0.6 -0.4 -0.3 -0.8 -0.2 -0.1 -0.5 -0.6 0.2 0.2
Medication: Blood pressure 2.0 3.8 13.5 2.1 1.8 3.7 2.0 2.2 2.9 2.5 0.8 2.1 1.5 2.3 2.3 2.2 2.2 0.7 2.3 1.7 -0.3 -2.0 1.6 1.7 0.8 0.2 1.1 2.3 1.4 2.0 2.1 1.2 2.6 2.4 1.1 1.4 2.4 1.4 2.4
Pain type(s) experienced in last month: Hip pain 6.0 7.6 12.6 3.3 3.0 2.6 2.9 3.0 3.5 3.2 2.2 3.1 2.9 2.1 2.9 3.2 2.7 1.9 2.9 3.5 0.8 -2.1 1.9 2.6 2.6 2.4 2.7 2.9 1.8 2.8 2.9 2.5 2.6 3.0 2.7 2.7 2.8 3.1 3.3
Supplements: Fish oil (including cod liver oil) 1.5 2.0 3.4 -1.8 -1.0 -1.6 -1.6 -1.7 -1.1 -1.7 -1.5 -1.6 -1.4 -1.8 -1.5 -1.7 -1.6 -0.1 -1.6 -1.5 -1.6 1.4 -0.9 -0.5 -1.4 -0.9 -1.6 -1.5 -0.5 -1.6 -1.6 -1.5 -1.2 -1.5 -1.6 -0.7 -1.5 -1.6 -1.4
High cholesterol (Self-reported) 0.7 1.2 2.6 1.6 0.6 0.9 1.3 1.2 1.0 0.7 0.5 1.0 0.4 0.6 1.6 1.2 1.6 0.4 1.3 1.0 1.0 -1.6 0.7 1.1 -0.2 0.3 1.4 1.6 1.0 0.6 1.1 1.4 0.9 1.3 1.2 1.2 1.3 1.3 0.9
Medication: Bendroflumethiazide 0.5 0.7 4.7 0.2 0.3 2.2 0.5 0.5 1.2 1.8 -0.5 0.5 0.3 0.6 0.7 0.5 0.6 0.0 0.7 0.3 -1.5 -0.8 1.4 0.3 0.2 -1.5 -0.6 0.7 0.5 0.5 0.4 -0.4 1.3 0.9 -0.6 0.3 0.8 -0.3 1.0
Medication: Paracetamol 1.9 2.9 7.1 1.8 2.1 2.5 1.8 1.9 1.6 2.7 -0.1 1.9 1.4 2.1 1.9 1.9 1.6 -0.2 1.9 1.4 0.3 -1.9 1.8 -0.6 2.0 1.1 1.0 1.8 0.6 2.0 1.7 1.4 2.0 2.2 1.2 1.1 1.8 1.3 2.2
Medication: Lisinopril 0.9 1.2 2.8 1.2 0.5 1.4 0.9 1.0 1.4 1.3 1.1 1.1 0.7 1.0 1.1 0.9 1.5 -0.5 1.2 0.9 0.6 -1.4 1.2 1.7 0.6 0.6 1.0 1.1 0.3 1.0 1.0 1.0 1.4 1.3 0.9 1.0 1.3 1.1 1.0
Medication: Atorvastatin 0.2 0.3 1.8 0.7 0.4 0.9 0.2 0.2 0.7 -0.1 0.3 -0.1 -0.4 0.8 0.2 0.1 0.0 -0.3 0.1 0.0 -1.3 -0.2 0.9 0.5 -1.2 0.3 -0.4 0.2 -0.2 0.1 0.2 -0.1 0.9 0.5 -0.4 -0.1 0.3 -0.2 0.4
Illnesses of father: High blood pressure 0.5 0.6 3.1 1.3 0.6 1.3 0.9 0.4 0.7 1.0 1.4 0.7 0.1 1.5 0.5 0.5 0.8 -0.2 0.5 1.0 0.4 -0.5 1.3 0.2 0.6 1.8 0.2 0.5 0.5 0.5 0.4 0.2 1.1 0.8 0.2 0.5 0.6 0.5 0.9
Alcohol drinker status: Never 0.8 0.9 3.4 1.0 0.3 0.6 0.5 0.7 -0.6 -0.2 1.4 0.4 -0.3 1.3 0.9 0.4 0.8 -0.3 1.0 0.8 1.4 -1.1 0.9 1.9 -1.4 1.5 1.1 1.0 1.0 0.9 0.9 1.4 1.4 0.3 1.2 0.6 0.9 0.7 -0.4
Ever smoked 0.2 0.3 1.3 -0.9 -0.5 -0.1 -0.4 -0.8 -1.1 -0.1 0.5 -0.3 -0.6 -0.4 -0.6 -0.8 -0.3 -0.1 -0.7 0.0 0.4 0.5 0.1 -0.5 -0.5 1.2 -0.2 -0.7 -0.1 -0.8 -0.9 -0.4 -0.4 -0.5 -0.3 -0.2 -0.6 -0.2 -0.7
Basal metabolic rate 1.2 6.5 11.5 -3.1 -3.4 -1.7 -2.1 -2.7 -2.2 -3.1 -2.6 -3.0 -2.0 -2.4 -2.6 -2.7 -2.8 -0.9 -2.6 -3.2 -2.1 2.3 -2.9 -2.9 -2.4 -3.0 -2.6 -2.7 -1.6 -2.5 -2.8 -2.6 -2.4 -2.4 -2.8 -1.4 -2.6 -2.5 -2.3
Leg fat percentage (left) 0.2 0.8 2.7 0.6 0.5 1.7 0.9 0.9 1.5 1.3 0.0 0.9 0.5 1.1 1.1 0.9 0.7 1.0 1.2 0.0 -1.3 -0.7 0.1 1.4 0.3 -1.0 0.3 1.2 0.2 0.6 0.8 0.2 1.2 1.1 0.1 0.9 1.0 0.4 1.0
Arm fat-free mass (left) 1.2 6.3 10.6 -2.9 -3.2 -1.9 -2.2 -2.7 -1.9 -3.1 -2.7 -2.9 -2.0 -2.5 -2.6 -2.6 -2.8 -1.2 -2.5 -3.1 -2.1 2.4 -3.3 -2.6 -2.5 -3.0 -2.5 -2.6 -1.6 -2.4 -2.8 -2.6 -2.4 -2.4 -2.7 -1.3 -2.5 -2.5 -2.2
Number of operations (self-reported) 3.6 5.3 9.6 2.3 1.7 1.6 1.6 2.5 1.5 2.2 2.7 2.5 1.0 3.1 2.7 2.2 2.5 1.8 3.0 1.9 1.1 -2.6 2.7 2.5 0.8 2.6 2.4 2.8 2.5 2.2 2.7 2.6 3.0 2.1 2.7 1.9 2.9 1.9 1.4
Average weekly beer plus cider intake 0.3 0.4 1.1 -0.6 -0.9 -1.0 -0.7 -0.8 -0.7 -0.7 0.5 -0.5 -1.0 -0.3 -0.7 -0.7 -0.7 0.0 -0.7 -0.3 0.7 0.8 -0.6 0.4 0.3 0.7 -0.0 -0.7 0.5 -1.1 -0.9 -0.2 -0.8 -0.8 -0.2 -0.2 -0.8 0.1 -0.9
Irritability 3.3 5.6 8.9 2.6 2.4 2.1 2.6 2.8 1.1 3.0 2.6 2.8 2.4 2.0 2.5 2.7 2.6 0.8 2.6 2.5 2.2 -2.3 2.5 1.2 2.8 2.0 2.5 2.5 1.1 2.7 2.7 2.4 2.4 2.5 2.4 1.4 2.5 2.4 2.4
Risk taking 1.5 2.2 5.4 1.5 1.8 2.0 1.2 1.5 1.4 2.3 0.6 2.0 0.9 1.9 1.8 1.5 1.9 1.1 1.6 1.1 0.3 -1.6 1.9 0.8 2.3 0.9 0.9 1.8 0.5 1.0 1.4 1.0 1.9 1.9 0.9 0.5 1.7 1.2 1.8
Ever had prostate specific antigen (PSA) test 0.2 0.2 1.8 0.2 -0.3 -0.9 -0.2 -0.1 -0.8 -0.6 -0.5 0.1 0.2 -0.6 -0.1 -0.1 -0.1 0.8 -0.1 -0.6 1.0 0.1 0.1 0.2 1.4 0.0 0.4 -0.1 -0.3 -0.1 -0.0 0.5 -0.7 -0.4 0.5 -0.5 -0.0 0.1 -0.6
Fractured/broken bones in last 5 years 0.2 0.3 3.0 -0.3 -0.1 0.7 -0.3 -0.4 0.3 0.2 0.2 -0.5 -0.5 0.1 -0.2 -0.4 -0.1 -0.7 -0.2 -0.5 -0.6 0.4 -0.4 -0.1 -0.8 -1.7 -0.9 -0.2 0.2 -0.3 -0.3 -0.8 -0.4 -0.4 -0.9 -0.4 -0.4 -1.0 -0.3
Age started oral contraceptive pill 3.7 4.6 16.0 -2.3 -1.7 -1.9 -2.4 -2.2 -2.1 -2.4 -1.9 -2.5 -2.4 -1.7 -2.0 -2.4 -2.3 -2.0 -1.9 -2.5 -1.1 1.7 -2.7 -1.0 -4.0 -2.3 -2.1 -1.9 -0.7 -2.0 -2.1 -1.8 -1.8 -2.4 -2.1 -1.4 -2.1 -2.5 -2.7
Diastolic blood pressure, automated reading 0.2 0.5 3.6 0.1 -1.2 1.1 -0.6 -0.5 0.6 0.2 0.2 -0.5 -1.1 0.7 -0.3 -0.6 -0.5 -0.8 -0.3 -0.6 -1.9 0.5 0.1 -0.4 -1.1 -0.7 -1.1 -0.2 0.2 -0.9 -0.6 -0.9 0.2 -0.1 -1.1 -0.4 -0.2 -1.0 -0.1
Ever depressed for a whole week 1.5 1.8 8.2 0.7 1.0 2.7 0.6 0.8 0.9 0.7 2.6 1.1 0.5 2.5 0.9 1.0 1.2 1.1 0.9 2.2 0.2 -0.7 1.1 0.1 1.1 2.9 0.9 0.9 1.7 0.2 0.6 0.7 1.4 1.5 0.9 1.4 1.1 1.3 1.5
Unable to work because of sickness or disability 0.2 0.2 1.5 -0.2 0.2 0.9 0.1 -0.1 1.2 -0.2 1.2 -0.2 -0.1 0.8 0.0 -0.0 0.2 0.0 -0.0 0.2 -1.2 0.2 0.0 0.5 -0.4 0.5 -0.2 0.1 0.7 -0.2 -0.3 -0.4 0.4 0.3 -0.3 0.3 0.1 0.1 0.4
Commuting to job workplace: Cycle 1.5 1.8 4.0 -1.6 -0.7 -1.6 -1.7 -1.5 -2.0 -1.9 -1.0 -1.7 -1.2 -1.5 -1.6 -1.5 -2.0 -1.6 -1.5 -1.1 0.1 1.3 -1.0 -0.1 -1.5 0.2 -1.1 -1.4 -1.1 -0.7 -1.2 -0.8 -1.0 -1.7 -0.8 -1.5 -1.3 -1.2 -1.6
Myopia 0.8 1.2 4.3 -1.3 -1.2 -0.2 -0.8 -1.3 -0.6 -1.7 -1.1 -1.4 -1.1 -0.8 -1.2 -1.2 -1.6 -0.3 -1.4 -0.9 -2.1 0.8 -1.5 -0.9 -0.9 0.1 -1.3 -1.2 -0.5 -1.1 -1.2 -1.2 -0.7 -0.8 -1.2 -0.8 -0.9 -1.0 -0.6
Vascular/heart problems diagnosed by doctor 1.5 4.0 19.0 -2.3 -1.3 -4.4 -1.9 -1.9 -3.2 -2.6 -1.1 -1.7 -1.3 -2.4 -2.0 -1.9 -1.8 -1.2 -2.1 -1.9 1.2 1.8 -2.4 -1.9 -1.0 -0.7 -0.5 -2.0 -1.7 -1.6 -1.6 -0.7 -2.6 -2.6 -0.7 -2.3 -2.3 -1.0 -2.7
Cholesterol lowering medication 1.1 1.6 3.2 1.6 1.4 1.8 1.2 1.4 1.4 1.4 0.4 1.4 0.6 1.0 1.4 1.4 1.3 -0.5 1.5 1.5 0.7 -1.2 1.2 0.8 1.3 0.6 1.5 1.5 0.4 1.2 1.4 1.3 1.4 1.5 1.2 1.3 1.4 1.5 1.4
Medication: Omeprazole (e.g. Zanprol) 1.9 2.3 9.2 1.7 1.7 1.4 1.7 1.6 1.6 1.5 1.0 1.5 1.3 0.8 1.7 1.7 1.7 0.5 1.7 1.4 1.0 -1.5 1.1 3.0 1.3 0.8 1.7 1.7 1.6 1.4 1.6 1.5 1.3 1.5 1.6 1.2 1.7 1.6 1.3
Pain experienced in last month 0.4 0.7 4.2 -1.0 -0.6 -0.3 -0.8 -0.8 -0.1 -1.1 -1.0 -1.1 -0.1 -1.2 -0.8 -0.8 -0.8 0.4 -0.6 -0.7 -0.8 0.7 -1.1 0.9 -2.0 -1.1 -0.8 -0.8 0.2 -0.6 -0.7 -0.7 -0.7 -1.0 -0.7 -0.3 -0.7 -1.0 -1.2
Supplements: Calcium 0.5 0.5 2.7 0.5 0.4 0.8 0.7 0.8 0.2 -0.1 0.6 0.6 0.0 1.1 0.7 0.8 0.7 0.1 0.6 0.8 0.3 -0.5 0.6 0.2 0.5 1.6 0.7 0.7 0.6 0.6 0.8 0.7 0.7 0.9 0.8 -0.2 0.7 0.8 1.1
Basal cell carcinoma (self-reported) 0.9 1.0 2.2 -1.0 -1.1 -1.1 -1.5 -1.3 -0.5 -1.1 -0.8 -1.2 -1.1 -1.2 -1.2 -1.1 -1.1 -0.9 -1.2 -1.0 -0.4 1.2 -0.7 -0.8 -0.5 -0.6 -1.1 -1.1 -0.4 -1.4 -1.4 -1.0 -1.1 -1.0 -0.9 -0.2 -1.1 -0.8 -0.7
Heart attack/myocardial infarction (self-reported) 0.3 0.3 2.4 -0.2 0.5 1.5 0.5 0.2 1.1 0.5 -0.4 0.1 0.2 0.2 0.2 0.3 0.0 -0.1 0.3 0.4 -1.4 -0.3 0.8 0.2 0.4 -0.2 -0.5 0.2 -0.1 0.3 0.1 -0.5 0.8 0.7 -0.5 0.9 0.4 -0.2 0.9
Deep venous thrombosis (DVT) (self-reported) 3.6 4.7 7.3 -2.4 -2.4 -2.0 -2.5 -2.3 -1.8 -2.6 -1.4 -2.3 -2.1 -1.2 -2.4 -2.3 -2.1 -1.4 -2.3 -2.7 -1.6 2.4 -1.5 -2.7 -1.3 -1.8 -2.4 -2.4 -2.0 -2.3 -2.2 -2.3 -2.1 -2.2 -2.3 -2.4 -2.2 -2.2 -1.9
Heart disease (siblings) 1.7 2.1 6.5 -1.2 -1.3 0.8 -1.0 -1.4 -0.6 -0.9 0.4 -1.7 -1.6 -0.7 -1.6 -1.2 -1.1 -1.3 -1.7 -1.0 -1.9 2.1 -0.0 -1.5 -0.8 -1.4 -2.2 -1.6 -2.5 -1.6 -1.5 -2.3 -1.2 -0.7 -2.4 -1.4 -1.6 -1.6 0.2
Alcohol drinker status: Previous 1.5 1.7 3.5 1.5 1.9 0.8 1.7 1.5 1.5 1.0 1.3 1.4 1.5 1.1 1.3 1.5 1.5 1.2 1.2 1.2 0.9 -1.2 -0.1 1.3 0.5 1.1 1.7 1.3 0.7 1.6 1.4 1.4 1.1 1.3 1.5 1.4 1.3 1.7 1.2
Pack years of smoking 1.3 1.9 7.5 0.9 1.3 1.9 1.2 1.0 1.3 0.7 2.7 0.9 0.6 1.5 1.2 1.0 1.3 0.4 1.1 2.6 0.6 -1.2 1.3 2.1 -0.1 1.9 1.3 1.3 1.2 1.2 1.1 1.1 1.7 1.2 1.2 1.8 1.2 1.3 1.0
Impedance of whole body 2.4 12.0 22.3 3.1 4.7 3.3 3.5 3.8 3.3 3.7 3.3 3.9 4.4 3.4 3.6 3.6 3.7 4.4 3.4 3.7 2.0 -3.7 3.6 0.8 3.0 3.8 3.1 3.4 2.4 3.7 3.7 3.4 3.8 3.6 3.3 1.9 3.6 3.3 3.3
Leg fat mass (left) 0.1 0.4 3.0 -0.7 -0.7 0.7 -0.1 -0.2 0.4 -0.2 -0.7 -0.4 -0.3 0.1 -0.1 -0.2 -0.5 0.6 -0.0 -1.0 -1.7 0.3 -0.9 0.2 -0.6 -1.7 -0.6 -0.1 -0.3 -0.4 -0.4 -0.7 0.1 0.1 -0.9 0.2 -0.1 -0.4 0.1
Arm predicted mass (left) 1.2 6.1 10.6 -2.7 -3.3 -1.9 -2.1 -2.6 -2.0 -3.0 -2.6 -2.8 -1.9 -2.5 -2.5 -2.6 -2.7 -1.3 -2.5 -3.0 -2.0 2.3 -3.1 -2.7 -2.4 -3.1 -2.4 -2.5 -1.5 -2.3 -2.7 -2.6 -2.4 -2.3 -2.7 -1.2 -2.5 -2.4 -2.2