TWAS hub - NRG4

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.502	0.0440	0.0e+00	0.607	0.552	0.611	0.578	0.624	1.7e-93	1.0e-80	1.5e-94	1.3e-86	7.1e-98
2	GTEx	Brain Cerebellar Hemisphere	0.570	0.0940	4.3e-07	0.411	NA	0.362	NA	0.369	1.1e-11	NA	3.5e-10	NA	2.2e-10
3	GTEx	Brain Cerebellum	0.397	0.0860	3.0e-06	0.235	NA	0.375	NA	0.332	1.4e-07	NA	4.6e-12	NA	1.4e-10
4	GTEx	Pituitary	0.313	0.0920	1.1e-03	0.289	NA	0.185	NA	0.229	5.8e-08	NA	2.1e-05	NA	1.8e-06
5	GTEx	Prostate	0.437	0.0910	2.7e-05	0.252	NA	0.060	NA	0.191	5.0e-07	NA	1.3e-02	NA	1.5e-05
6	GTEx	Testis	0.710	0.0530	0.0e+00	0.323	NA	0.504	NA	0.508	6.2e-15	NA	1.9e-25	NA	1.1e-25
7	TCGA	Brain Lower Grade Glioma	0.102	0.0374	1.2e-09	0.078	0.076	0.061	NA	0.070	3.2e-09	5.4e-09	1.6e-07	NA	2.5e-08
8	TCGA	Prostate Adenocarcinoma	0.135	0.0472	1.8e-15	0.164	0.163	0.153	NA	0.151	8.4e-17	9.9e-17	9.4e-16	NA	1.6e-15
9	TCGA	Testicular Germ Cell Tumors	0.112	0.0600	5.5e-03	0.027	0.071	0.108	NA	0.069	3.7e-02	1.6e-03	1.3e-04	NA	2.0e-03

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Blood Red Count	13.8	133.3	193.2	-9.6	-13.9	-12.9	-9.9	10.9	-11.8	-13.4	10.7	-9.9
Gout (self-reported)	5.6	7.7	13.9	2.2	3.3	3.0	2.1	-2.7	2.7	3.7	-2.2	2.6
Alcohol drinker status: Never	5.4	6.4	9.7	-2.2	-3.1	-2.9	-2.4	2.3	-2.7	-3.0	2.3	-1.4
Diabetes (father)	4.6	5.7	8.8	-2.1	-2.8	-2.6	-1.9	2.3	-2.6	-3.0	2.0	-1.8
Depression (self-reported)	4.1	4.9	7.2	2.5	2.7	2.6	2.5	-0.9	2.4	2.3	-1.0	2.2
Ever unenthusiastic/disinterested for a whole week	3.8	4.7	6.8	2.6	2.5	2.5	2.6	-0.7	2.3	2.2	-0.8	2.1
Type 2 Diabetes (T2D) (2018)	3.6	6.8	13.2	-1.3	-2.8	-2.3	-1.2	3.6	-2.3	-3.1	3.4	-2.4
Illnesses of mother	3.6	4.4	7.1	-2.4	-2.7	-2.5	-2.6	1.3	-2.5	-1.9	0.8	-1.4
Medication: Allopurinol	3.5	4.6	7.7	1.7	2.5	2.3	1.6	-2.0	2.1	2.7	-1.3	2.8
Major Depression (MDD)	3.4	4.1	6.5	2.4	2.5	2.3	2.5	0.5	2.4	1.9	0.2	2.0
Serious illness, injury or assault to yourself	3.4	4.1	5.6	2.0	2.4	2.1	2.0	-1.3	2.3	2.2	-1.5	2.1
Diabetes (self-reported)	3.3	5.1	11.4	-0.9	-2.3	-1.8	-0.8	3.4	-1.7	-2.6	2.9	-2.5
Medication: Metformin	3.2	4.5	11.2	-0.6	-2.2	-1.6	-0.7	3.3	-1.6	-2.3	3.3	-1.5
Mouth/teeth dental problems: Dentures	3.2	5.4	10.9	-2.7	-2.4	-2.4	-2.6	0.6	-2.5	-2.3	0.3	-3.3
Loneliness, isolation	3.1	4.3	6.6	2.2	2.6	2.4	2.4	-1.1	2.2	2.6	-0.8	1.5
Seen a psychiatrist for nerves, anxiety, tension or depression	3.0	3.9	6.8	1.1	2.4	2.0	1.2	-2.6	1.9	2.3	-2.5	-0.8
Financial situation satisfaction	3.0	3.7	5.9	2.2	2.3	2.3	2.0	-1.0	2.4	2.3	-1.1	0.1
High blood pressure (mother)	2.8	3.9	6.0	1.9	2.4	2.4	1.9	-1.7	2.0	2.3	-1.6	1.4
Alzheimer’s Disease (in mother)	2.7	3.1	4.6	1.3	2.1	1.9	1.3	-2.1	1.7	2.1	-1.9	1.0
Rheumatoid Arthritis	2.7	3.8	7.2	2.7	1.9	2.1	2.6	0.7	2.5	1.5	0.4	1.8
Ever highly irritable/argumentative for 2 days	2.7	3.3	4.5	-2.1	-2.0	-2.1	-1.9	0.8	-1.9	-2.1	0.7	-1.9
Health satisfaction	2.7	3.5	5.9	1.9	2.4	2.2	1.9	-1.4	2.1	2.2	-1.2	0.8
Diabetes diagnosed by doctor	2.7	4.4	12.4	-0.5	-2.1	-1.5	-0.4	3.5	-1.4	-2.4	3.1	-1.7
Illnesses of father: High blood pressure	2.7	3.4	5.8	1.8	2.2	2.1	1.8	-1.4	1.9	2.4	-1.3	1.0
Number of treatments/medications taken	2.6	4.8	14.2	0.4	2.1	1.7	0.2	-3.5	1.6	2.4	-3.8	-0.9
Myopia	2.6	3.8	6.2	-2.3	-2.4	-2.3	-2.5	0.7	-2.2	-1.9	0.6	-1.6
Ever depressed for a whole week	2.4	3.0	4.7	1.4	2.2	1.9	1.5	-1.9	1.8	2.1	-1.8	0.4
Respiratory disease	2.2	4.9	8.0	2.5	2.6	2.5	2.8	-0.7	2.6	2.1	-0.5	2.0
Leg fat-free mass (left)	2.2	11.8	16.4	3.9	4.0	3.9	4.1	-1.2	3.8	3.7	-1.3	3.4
Leg predicted mass (left)	2.2	11.7	16.1	3.9	4.0	3.9	4.0	-1.3	3.8	3.7	-1.3	3.4
Pulse wave peak to peak time	2.2	2.6	3.7	1.5	1.9	1.8	1.4	-1.6	1.9	1.7	-1.4	1.4
Eye problems/disorders: None of the above	2.2	2.5	4.1	-1.0	-1.8	-1.5	-1.1	1.9	-1.4	-1.9	2.0	-1.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	2.2	2.6	5.2	2.3	1.5	1.7	2.2	0.9	2.2	1.0	0.6	0.9
Medication: Lisinopril	2.1	2.7	5.0	2.1	1.8	1.8	2.2	0.2	1.9	1.8	0.0	1.2
Arm fat-free mass (left)	2.1	10.6	17.4	3.7	3.6	3.5	3.9	-0.7	3.4	3.3	-0.7	4.2
Alzheimer’s Disease (including proxy)	2.0	2.9	4.3	1.5	2.1	2.0	1.5	-1.6	1.8	1.9	-1.7	1.0
Whole body fat-free mass	2.0	11.3	15.2	3.7	3.9	3.8	3.9	-1.3	3.6	3.5	-1.3	3.8
Whole body water mass	2.0	11.5	15.3	3.8	3.9	3.8	3.9	-1.3	3.6	3.6	-1.3	3.9
Basal metabolic rate	2.0	10.8	14.7	3.7	3.8	3.7	3.8	-1.2	3.6	3.5	-1.1	3.7
Arm fat-free mass (right)	1.9	9.9	15.5	3.6	3.5	3.4	3.7	-0.9	3.4	3.2	-0.9	3.9
Leg fat-free mass (right)	1.9	10.2	14.2	3.6	3.8	3.6	3.8	-1.2	3.5	3.3	-1.3	3.2
Leg predicted mass (right)	1.9	10.1	14.2	3.6	3.7	3.6	3.8	-1.2	3.5	3.3	-1.3	3.3
Fractured/broken bones in last 5 years	1.9	2.4	3.8	1.5	1.9	1.9	1.6	-1.2	1.7	2.0	-0.8	0.9
Arm predicted mass (left)	1.9	9.4	15.2	3.4	3.4	3.4	3.6	-0.8	3.2	3.2	-0.8	3.9
Trunk fat-free mass	1.8	10.4	14.1	3.4	3.7	3.6	3.6	-1.4	3.4	3.4	-1.4	3.8
Pulse wave Arterial Stiffness index	1.8	2.1	3.1	-1.2	-1.8	-1.6	-1.1	1.6	-1.7	-1.5	1.4	-1.0
Trunk predicted mass	1.8	10.4	13.9	3.5	3.7	3.6	3.6	-1.4	3.4	3.4	-1.4	3.7
Osteoporosis (self-reported)	1.8	2.2	6.0	-1.5	-1.6	-1.6	-1.7	0.4	-1.2	-1.5	0.0	-2.4
Supplements: Calcium	1.8	2.0	4.9	-1.1	-1.6	-1.6	-1.0	1.4	-1.1	-2.2	1.2	-1.2
Alcohol intake frequency.	1.7	3.9	13.2	2.3	1.4	1.5	2.2	1.0	1.7	1.5	1.4	3.6
Body Mass Index (BMI) (2010)	1.6	2.2	3.1	1.2	1.7	1.6	1.0	-1.6	1.6	1.7	-1.7	0.7
Arm predicted mass (right)	1.6	8.3	14.4	3.3	3.2	3.1	3.5	-0.6	3.0	2.7	-0.5	3.8
Average weekly beer plus cider intake	1.6	2.4	5.1	-2.1	-1.1	-1.2	-2.3	-1.4	-1.8	-0.4	-1.4	-1.3
Townsend deprivation index at recruitment	1.5	2.1	3.7	1.9	1.4	1.6	1.9	0.3	1.8	0.9	0.5	1.6
Alcohol drinker status: Previous	1.5	1.7	5.2	1.5	1.1	1.0	1.7	0.4	1.1	1.1	0.8	2.3
Fasting Glucose	1.4	1.7	4.8	-1.8	-1.6	-0.6	0.4	1.4	-2.2	-0.8	1.4	-0.2
Pain all over the body in last month	1.4	1.6	2.3	0.8	1.5	1.4	0.9	-1.4	1.1	1.5	-1.3	1.0
Alcohol intake versus 10 years previously	1.4	2.1	4.6	1.2	1.5	1.6	0.9	-1.2	1.5	2.1	-1.3	1.4
Pulse wave reflection index	1.4	1.7	2.6	-1.3	-1.6	-1.6	-1.3	1.0	-1.6	-1.4	1.0	-0.6
Medication: Omeprazole	1.4	1.6	5.3	0.3	1.2	0.9	0.1	-2.1	0.7	1.4	-2.3	0.0
Family relationship satisfaction	1.4	1.7	2.8	1.4	1.6	1.7	1.4	-0.9	1.5	1.4	-0.9	-0.5
Mineral and other dietary supplements	1.4	1.9	2.8	1.7	1.4	1.7	1.6	-0.1	1.6	1.6	0.0	1.3
Triglycerides	1.3	2.2	4.3	0.8	1.5	1.3	0.7	-1.7	1.2	2.1	-1.5	1.9
Supplements: Glucosamine	1.3	1.6	3.4	-1.3	-1.5	-1.6	-1.1	0.6	-1.6	-1.8	0.9	-0.6
Financial difficulties in last 2 years	1.3	1.8	3.7	1.9	1.2	1.4	1.9	0.7	1.4	0.9	0.6	1.4
Weight	1.3	6.2	9.2	2.9	2.9	2.7	3.0	-0.6	2.8	2.7	-0.6	2.6
Heart disease (mother)	1.3	1.6	3.4	1.6	0.9	1.0	1.8	0.9	1.2	0.3	1.3	1.6
Number of full sisters	1.3	1.6	4.6	-0.3	-1.2	-1.0	-0.4	2.2	-1.2	-1.3	2.0	0.1
Unable to work because of sickness or disability	1.3	1.7	3.8	1.6	1.3	1.2	1.9	0.7	1.1	0.7	0.9	1.5
HbA1C	1.2	1.3	2.7	-0.3	-0.5	-1.5	-0.7	1.4	-0.5	-1.6	1.5	-1.2
Height	1.2	22.3	38.8	4.8	5.2	5.2	4.9	-2.6	5.0	4.8	-2.7	6.2
Number of incorrect matches in round	1.2	2.0	6.0	-1.6	-1.1	-1.4	-1.6	-0.3	-1.4	-1.3	-0.5	-2.4
Frequency of tenseness / restlessness in last 2 weeks	1.2	1.8	3.4	0.6	1.4	1.1	0.6	-1.8	1.1	1.9	-1.7	1.2
Had other major operations	1.2	1.4	2.8	-1.2	-1.5	-1.7	-1.2	0.8	-1.4	-1.2	0.9	-0.4
Forced vital capacity (FVC)	1.2	4.4	7.9	2.1	2.2	2.3	2.2	-1.1	2.3	2.1	-1.3	2.8
Loud music exposure frequency	1.2	1.3	3.6	0.3	1.2	0.8	0.3	-1.9	0.5	1.2	-1.9	0.9
Fluid intelligence score	1.1	2.2	7.1	-0.2	-1.5	-1.2	-0.1	2.6	-0.6	-1.5	2.7	0.2
Standing height	1.1	10.6	16.3	3.2	3.6	3.6	3.2	-2.0	3.6	3.4	-2.1	4.0
Length of working week for main job	1.1	1.2	2.4	1.3	1.0	1.1	1.6	0.2	1.3	0.9	0.4	1.2
Forced vital capacity (FVC), Best measure	1.1	4.1	7.5	1.9	2.1	2.2	1.9	-1.3	2.2	2.2	-1.2	2.7
Number of children fathered	1.1	1.2	3.0	-1.3	0.0	-0.4	-0.9	-1.5	-1.2	-0.1	-1.7	-1.2
Emphysema/chronic bronchitis	1.1	1.2	2.8	0.9	1.3	1.2	1.0	-0.9	1.2	1.7	-1.0	0.5
Medication: Blood pressure	1.1	2.0	3.7	1.9	1.5	1.5	1.9	0.3	1.7	1.1	0.3	1.2
Comparative height size at age 10	1.1	6.1	8.2	1.9	2.9	2.6	1.9	-2.6	2.6	2.6	-2.5	2.5
Illness, injury, bereavement, stress in last 2 years	1.1	1.3	2.3	-1.5	-1.2	-1.3	-1.5	-0.5	-1.2	-0.6	-0.1	-1.4
Illnesses of siblings: Diabetes	1.1	1.4	2.1	-1.4	-1.3	-1.4	-1.1	0.7	-1.5	-1.3	0.6	-0.8
Eye problems/disorders: Glaucoma	1.1	1.3	1.8	1.1	1.3	1.3	1.2	-0.6	1.2	1.0	-1.0	1.3
Age at First Birth	1.0	1.5	2.9	1.0	1.4	1.6	0.9	-0.5	1.7	1.4	-1.5	0.3
Schizophrenia (2014)	1.0	2.3	3.7	-1.2	-1.7	-1.9	-1.2	1.3	-1.5	-1.9	1.6	-0.9
Hair/balding pattern: Pattern 2	1.0	1.3	3.8	0.2	1.2	0.9	0.2	-1.9	0.7	1.1	-1.9	0.4
Qualifications: None of the above	1.0	2.1	3.2	-1.8	-1.5	-1.7	-1.6	0.5	-1.8	-1.3	0.4	-1.8
Forced expiratory volume in 1-second (FEV1)	1.0	3.5	5.7	2.0	2.0	2.1	2.0	-0.7	2.0	1.9	-1.0	2.4
Forced expiratory volume in 1-second (FEV1), Best measure	1.0	3.1	5.0	1.8	1.9	2.0	1.8	-0.8	1.9	1.9	-0.9	2.2
Reason for reducing amount of alcohol drunk: Health precaution	1.0	1.2	2.0	-0.9	-1.3	-1.2	-0.8	1.0	-1.4	-1.4	1.1	0.6
Medication: Paracetamol	1.0	1.5	4.8	-0.0	1.0	0.6	-0.1	-2.2	0.6	1.5	-2.0	-0.8
Basal cell carcinoma (self-reported)	1.0	1.1	1.8	-1.1	-1.3	-1.1	-1.2	0.4	-1.4	-1.2	0.4	-1.0
Verbal and Numeric Reasoning (VNR)	0.9	2.2	4.9	-0.9	-1.8	-1.6	-0.8	2.0	-1.2	-1.5	2.2	-0.2
Coronary Artery Disease (CAD)	0.9	1.1	2.2	1.1	1.2	1.4	1.5	-0.8	1.3	1.1	-0.2	-0.0
Lung FEV1/FVC ratio	0.9	4.6	8.8	-2.5	-2.3	-2.2	-2.7	0.5	-3.0	-2.1	-0.0	-2.0
Allergy	0.9	2.0	3.7	-1.6	-1.8	-1.7	-1.9	0.6	-1.9	-1.1	0.6	0.1
Blood clot in the leg (DVT)	0.9	1.1	3.0	1.5	1.2	1.1	1.7	0.5	1.1	0.3	0.2	0.6
Medication: Amlodipine	0.9	1.3	2.8	1.3	1.4	1.2	1.4	-0.5	1.7	0.9	-0.6	0.4
Shortness of breath walking on level ground	0.9	1.0	1.7	-0.9	-1.2	-1.1	-0.9	0.9	-1.3	-1.1	0.9	-0.7
Eye problems/disorders: Cataract	0.9	1.1	2.8	-0.0	1.0	0.7	0.3	-1.7	0.4	1.2	-1.6	0.9
Medication: Gliclazide	0.9	1.0	3.8	-0.4	-0.9	-0.7	-0.4	1.1	-0.8	-1.0	0.9	-2.0
Ever taken oral contraceptive pill	0.9	1.0	1.6	-1.3	-1.1	-1.1	-1.2	0.2	-1.3	-0.7	0.2	-1.0
Hearing aid user	0.9	1.1	1.8	1.3	1.3	1.3	1.3	-0.3	1.2	1.0	-0.4	0.0
Pain type(s) experienced in last month: Hip pain	0.9	1.1	1.8	0.8	1.3	1.2	0.9	-1.2	1.1	1.2	-1.0	0.8
Supplements: Fish oil (including cod liver oil)	0.9	1.2	2.6	-1.3	-0.8	-1.1	-1.4	-0.6	-1.0	-0.9	-0.7	-1.6
Medication: Atorvastatin	0.9	1.1	2.1	-1.3	-1.1	-1.1	-1.3	0.2	-1.5	-1.0	-0.1	-1.1
HDL Cholesterol	0.8	1.3	2.0	-1.2	-1.4	-1.1	-1.2	0.8	-1.2	-1.2	0.7	-1.4
Chronotype (morning person)	0.8	1.9	3.2	-1.8	-1.5	-1.7	-1.8	0.1	-1.7	-1.2	0.2	-1.1
Impedance of leg (left)	0.8	3.8	6.6	-1.8	-2.6	-2.2	-1.9	1.7	-1.9	-2.4	1.7	-0.9
Past tobacco smoking	0.8	1.5	3.7	1.8	0.9	1.0	1.9	1.1	1.4	0.4	1.0	0.9
Mouth/teeth dental problems	0.8	1.2	1.8	1.1	1.2	1.2	0.9	-0.8	1.4	1.3	-0.7	1.0
Happiness	0.8	0.9	1.8	1.0	1.1	1.2	1.2	-0.5	1.3	0.9	-0.3	-0.6
Asthma	0.8	1.6	2.7	1.3	1.6	1.5	1.6	-0.5	1.4	1.3	-0.5	1.0
Seen doctor (GP) for nerves, anxiety, tension or depression	0.8	1.3	2.4	0.7	1.4	1.2	0.7	-1.6	1.1	1.2	-1.4	-0.2
Medication: Paracetamol	0.8	1.3	4.1	-1.0	0.1	-0.3	-1.0	-2.0	-0.4	0.7	-1.9	-1.2
Medication for cholesterol, blood pressure or diabetes	0.8	1.3	2.0	-1.1	-1.4	-1.3	-1.0	0.9	-1.4	-1.4	1.0	-0.5
High blood pressure (siblings)	0.8	1.1	3.9	-0.0	1.1	0.8	0.2	-1.7	0.6	1.0	-2.0	-0.2
Suffer from ‘nerves’	0.8	1.3	4.7	0.0	-1.0	-0.6	0.1	1.9	-0.6	-0.9	2.2	0.7
Qualifications: NVQ or HND or HNC or equivalent	0.8	1.0	3.4	0.1	1.0	0.8	0.1	-1.8	0.5	0.8	-1.6	0.4
Asthma (self-reported)	0.8	1.6	2.5	1.3	1.6	1.4	1.6	-0.5	1.4	1.3	-0.5	1.0
Commuting to job workplace: Public transport	0.8	1.0	1.7	1.2	1.2	1.2	1.2	-0.4	1.3	0.9	-0.4	-0.1
Medication: Bendroflumethiazide	0.8	1.2	2.0	0.9	1.4	1.2	1.0	-1.1	0.8	1.4	-1.2	0.9
Cholesterol lowering medication	0.8	1.1	2.2	-0.7	-1.3	-1.2	-0.9	1.2	-1.1	-1.5	0.9	-0.7
Breast Cancer	0.7	1.6	3.8	1.3	1.3	1.4	1.3	-0.4	1.4	1.2	-0.6	1.9
Type 2 Diabetes (T2D) (2012)	0.7	0.8	1.8	-1.1	-0.7	-0.8	-1.2	-0.7	-0.5	-0.3	-0.9	-1.3
Average weekly spirits intake	0.7	0.9	1.9	1.2	1.1	1.2	1.0	-0.5	1.4	0.8	-0.6	-0.0
Ever had hysterectomy (womb removed)	0.7	0.8	1.6	-0.2	-0.9	-0.9	-0.2	1.3	-0.7	-1.1	1.1	-0.9
Supplements: Zinc	0.7	0.8	2.6	0.5	-0.3	-0.1	0.7	1.5	-0.2	-0.7	1.6	0.9
Taking other prescription medications	0.7	1.0	2.3	0.4	1.1	0.9	0.4	-1.3	1.0	1.2	-1.5	0.4
Bilateral oophorectomy (both ovaries removed)	0.7	0.8	1.8	-0.8	-0.1	-0.4	-0.8	-1.3	-0.8	0.4	-1.2	-1.3
Lung cancer (father)	0.7	0.8	1.5	1.2	0.6	0.8	1.1	1.0	0.8	0.9	0.7	0.7
Whole body fat mass	0.7	2.7	4.9	2.1	1.8	1.7	2.2	0.2	2.0	1.6	0.2	1.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.7	0.8	1.2	-0.7	-1.1	-1.1	-0.7	1.1	-0.9	-0.9	1.0	-0.1
Illnesses of father: Heart disease	0.7	0.9	3.3	-0.3	0.6	0.5	-0.2	-1.6	0.3	0.6	-1.8	-1.2
Smoking status: Previous	0.7	1.0	2.4	-1.4	-0.8	-0.8	-1.6	-0.9	-1.1	-0.3	-0.9	-0.8
Back pain experienced in last month	0.7	1.0	2.8	0.2	1.0	0.8	0.1	-1.6	0.8	1.1	-1.7	0.1
Wears glasses or contact lenses	0.7	0.8	1.8	-1.1	-0.3	-0.4	-1.2	-1.4	-0.4	0.1	-1.3	-1.0
Ever had prostate specific antigen (PSA) test	0.7	0.8	1.7	-1.3	-0.4	-0.7	-1.0	-0.7	-1.1	-0.4	-0.7	-1.2
Impedance of whole body	0.7	3.3	5.7	-2.0	-2.4	-2.1	-2.1	1.0	-1.8	-2.0	0.9	-1.5
Schizophrenia vs Biploar Disorder	0.6	0.8	2.1	0.2	1.0	0.7	0.4	-1.4	0.9	0.8	-1.5	-0.8
Prostate Cancer	0.6	0.9	2.8	-0.2	-0.9	-0.6	-0.2	1.4	-0.6	-1.2	1.7	-0.0
Heel T-Score	0.6	4.7	15.9	1.8	-0.2	0.3	1.9	3.6	0.7	-0.5	4.0	2.3
Hypothyroidism (self reported)	0.6	1.3	1.9	1.1	1.3	1.4	1.4	-0.3	1.1	1.4	-0.3	1.4
Medication for hormone replacement therapy	0.6	0.7	2.2	-0.7	0.0	-0.3	-0.9	-1.5	-0.3	0.5	-1.4	0.5
Hayfever, allergic rhinitis or eczema	0.6	1.2	2.6	1.1	1.3	1.3	1.1	-0.8	1.6	0.8	-0.8	-0.6
Multivitamins +/- minerals	0.6	0.7	1.3	-1.1	-0.8	-0.8	-1.0	-0.1	-1.1	-0.4	-0.4	-1.1
Trunk fat mass	0.6	2.8	5.0	2.1	1.8	1.7	2.2	0.2	1.9	1.6	0.2	1.7
Hearing difficulty/problems with background noise	0.6	0.9	2.5	1.1	0.6	0.8	1.2	0.6	0.8	0.7	0.9	1.6
Illnesses of siblings	0.6	0.9	3.9	0.5	-0.5	-0.2	0.3	1.6	-0.1	-0.6	2.0	0.6
Medication: Ibuprofen (e.g. Nurofen)	0.6	0.8	1.5	-1.1	-1.1	-1.2	-1.2	-0.2	-1.2	-0.6	0.1	-0.2
Arm fat mass (right)	0.6	2.5	4.0	2.0	1.8	1.7	2.0	-0.1	1.8	1.8	0.0	1.5
Exposure to tobacco smoke at home	0.6	0.7	1.3	1.0	1.0	1.1	1.0	-0.3	0.9	0.7	0.2	0.8
Mouth/teeth dental problems: Bleeding gums	0.6	0.8	2.3	-0.1	-0.9	-0.7	-0.1	1.4	-0.6	-0.9	1.5	0.7
Wheeze or whistling in the chest in last year	0.6	1.0	1.9	0.6	1.4	1.0	1.0	-1.1	0.8	1.3	-0.9	0.6
Leg fat mass (right)	0.6	2.3	4.5	2.0	1.6	1.5	2.1	0.3	1.8	1.4	0.5	1.3
Supplements: Vitamin C	0.6	0.7	1.2	-0.5	-1.0	-1.0	-0.7	0.8	-0.8	-1.1	0.9	-0.8
Medication: Aspirin	0.6	0.8	2.0	1.4	0.6	0.9	1.1	0.9	1.1	0.4	0.7	0.6
Illnesses of father: None of the above (group 1)	0.6	0.7	3.2	-0.1	-0.6	-0.4	-0.4	0.8	-0.3	-0.3	1.2	1.8
Arm fat mass (left)	0.6	2.4	3.9	1.9	1.8	1.6	2.0	-0.1	1.8	1.7	0.1	1.5
Guilty feelings	0.6	0.8	1.4	1.1	0.9	1.0	1.2	0.2	0.8	1.2	0.2	1.0
Mother’s age at death	0.6	0.7	2.0	0.2	1.0	0.7	0.4	-1.3	0.9	0.7	-1.4	-0.4
Ever smoked	0.6	1.0	2.4	-1.5	-0.8	-0.8	-1.5	-0.8	-1.1	-0.4	-0.6	-0.8
Deep venous thrombosis (DVT) (self-reported)	0.6	0.7	2.2	1.2	0.8	0.7	1.5	0.8	0.7	-0.1	0.5	0.5
Intelligence (Savage-Jansen 2018)	0.5	1.4	5.4	0.3	-0.9	-0.5	0.2	2.2	-0.4	-0.9	2.3	0.6
Schizophrenia (2018)	0.5	1.0	3.5	0.7	-0.3	-0.5	0.8	1.8	0.1	-0.8	1.9	0.1
Ulcerative Colitis (UC)	0.5	1.0	1.7	-0.9	-1.2	-1.1	-1.2	0.8	-0.9	-1.3	0.7	-0.8
Blood Platelet Count	0.5	5.8	9.0	-1.4	-2.6	-2.4	-1.4	2.7	-2.0	-3.0	2.5	-2.9
BMI	0.5	3.1	6.8	2.5	1.8	1.9	2.6	0.9	1.8	1.6	0.8	1.1
Medication: Co-codamol	0.5	0.6	1.9	-0.0	0.9	0.7	0.2	-1.3	0.2	0.9	-1.4	-0.2
Impedance of leg (right)	0.5	2.6	4.8	-1.5	-2.2	-1.9	-1.7	1.3	-1.5	-1.8	1.5	-0.9
Tinnitus: Yes, but not now, but have in the past	0.5	0.5	1.3	0.8	0.2	0.3	0.8	1.1	0.4	-0.2	0.8	0.9
Chronic bronchitis/emphysema (father)	0.5	0.5	1.2	0.3	0.9	0.7	0.6	-1.1	0.4	0.9	-0.9	0.4
Medication: Ramipril	0.5	0.7	1.9	0.9	0.1	0.5	0.7	1.0	0.3	-0.1	1.3	1.4
Hair/balding pattern: Pattern 3	0.5	0.7	2.3	0.0	-0.9	-0.5	-0.0	1.5	-0.2	-0.9	1.5	-0.2
Noisy workplace	0.5	0.6	1.0	0.8	1.0	0.9	0.7	-0.5	0.9	1.0	-0.6	0.0
Medication: Cholesterol lowering	0.5	0.7	1.2	0.5	1.0	1.0	0.5	-0.9	0.9	1.1	-1.1	-0.2
Glaucoma (self-reported)	0.5	0.6	1.3	0.7	0.9	0.8	0.7	-0.7	0.9	0.7	-1.2	0.4
Neck or shoulder pain in last month	0.5	0.6	3.1	0.8	0.5	0.6	0.7	0.4	0.6	0.6	0.3	1.8
Forced expiratory volume in 1-second (FEV1), predicted	0.5	1.1	1.9	1.0	1.2	1.2	1.1	-0.7	0.9	1.4	-0.6	1.3
Handedness (chirality/laterality): Left-handed	0.5	0.5	1.4	0.8	0.2	0.3	1.0	1.2	0.4	-0.5	1.2	-0.3
Leg fat mass (left)	0.5	2.1	4.2	1.9	1.5	1.4	2.0	0.5	1.6	1.2	0.6	1.4
Mean Putamen Volume	0.4	0.4	1.5	0.8	0.5	0.7	0.5	-0.6	1.2	0.6	-0.3	-0.1
Neuroticism (2016)	0.4	0.6	1.8	-0.2	-0.7	-0.9	-0.2	1.3	-0.3	-0.9	0.9	-1.0
Primary Biliary Cirrhosis	0.4	0.6	1.0	-1.0	-0.6	-0.8	-1.0	-0.5	-0.7	-0.0	-0.6	-1.0
Blood Eosinophil Count	0.4	2.7	6.2	1.9	1.7	1.6	1.7	-0.3	1.8	1.8	0.0	2.5
Hearing difficulty/problems: Yes	0.4	0.6	1.0	1.0	0.5	0.8	0.9	0.5	0.8	0.4	0.6	0.9
Vitamin and mineral supplements	0.4	0.6	1.4	0.9	0.5	0.5	0.9	0.6	0.9	0.3	0.6	1.2
Severe depression (siblings)	0.4	0.5	0.8	0.4	0.8	0.7	0.4	-0.8	0.6	0.9	-0.8	0.4
Age when periods started (menarche)	0.4	1.1	1.5	0.9	1.1	1.2	0.7	-1.0	0.8	1.0	-1.2	1.2
Stomach or abdominal pain in last month	0.4	0.5	1.6	-0.1	-0.6	-0.5	0.0	1.3	-0.3	-0.7	1.2	-0.6
Medication: Levothyroxine sodium	0.4	0.6	1.3	0.7	0.9	0.9	0.9	-0.3	0.6	1.2	-0.2	0.9
Sitting height	0.4	3.1	8.1	1.2	1.8	1.6	1.2	-1.6	1.6	1.8	-1.5	2.9
Had menopause	0.4	0.5	1.1	-0.6	-0.8	-0.9	-0.6	0.7	-0.5	-1.0	0.9	0.1
Heel bone mineral density (BMD) T-score, automated (right)	0.4	0.9	1.6	1.1	0.4	0.6	1.1	0.9	0.9	0.6	1.3	1.1
Hip circumference	0.4	1.6	2.4	1.3	1.5	1.3	1.4	-0.6	1.5	1.6	-0.5	1.1
Worrier / anxious feelings	0.4	0.8	1.4	-0.5	-1.1	-1.0	-0.5	1.1	-0.5	-1.0	1.2	-0.9
Pulse rate	0.4	0.6	1.7	-0.6	0.1	0.0	-0.7	-1.3	-0.3	0.6	-1.3	-1.1
Impedance of arm (left)	0.4	1.7	3.5	-1.6	-1.5	-1.3	-1.8	-0.1	-0.9	-1.1	-0.2	-1.9
Hypothyroidism/myxoedema (self-reported)	0.4	0.8	1.8	0.9	0.9	0.9	1.1	0.1	0.7	1.0	0.3	1.3
Exposure to tobacco smoke outside home	0.4	0.5	1.0	1.0	0.7	0.8	1.0	0.4	1.0	0.4	0.2	0.4
Worry too long after embarrassment	0.4	0.6	1.8	0.7	-0.3	0.1	0.5	1.2	0.3	-0.2	1.4	1.2
Qualifications: College or University degree	0.4	1.3	2.9	1.2	1.1	1.1	1.4	0.1	1.3	1.2	0.2	1.7
Mean time to correctly identify matches	0.4	0.8	4.9	-0.8	-0.6	-0.6	-0.8	-0.1	-0.7	-0.6	-0.1	-2.2
Leg pain on walking	0.4	0.5	1.2	0.9	0.6	0.5	1.1	0.6	0.2	0.1	0.7	0.9
Medication: Aspirin	0.4	0.5	1.2	0.9	0.2	0.5	0.7	1.1	0.7	0.0	0.8	0.6
Hypertension (Self-reported)	0.4	1.1	2.2	1.4	0.7	0.7	1.5	0.9	1.0	0.2	1.1	1.4
Commuting to job workplace: Walk	0.4	0.4	1.2	0.2	-0.6	-0.2	-0.0	1.0	-0.3	-0.3	1.1	0.9
Risk taking	0.4	0.6	2.1	-0.0	0.6	0.6	-0.1	-1.5	0.4	1.0	-1.1	-0.5
Age started oral contraceptive pill	0.4	0.5	0.7	-0.4	-0.7	-0.7	-0.3	0.9	-0.5	-0.8	0.7	-0.9
Heart disease (siblings)	0.4	0.5	2.1	-0.5	0.2	-0.0	-0.6	-1.3	-0.1	0.3	-1.5	-0.3
Alzheimer’s Disease (in father)	0.3	0.3	0.9	0.8	0.5	0.7	0.6	0.1	0.9	0.4	-0.4	0.5
Reaction Time	0.3	0.6	3.7	-0.6	-0.4	-0.4	-0.7	-0.3	-0.4	-0.4	-0.2	-1.9
Ovarian Cancer	0.3	0.4	1.5	-0.1	0.3	0.4	-0.2	-0.8	0.2	0.5	-1.2	0.9
Crohns Disease (2012)	0.3	0.5	1.6	0.7	0.5	0.3	0.8	0.4	0.5	0.8	0.5	1.2
Blood White Count	0.3	2.3	3.3	-1.6	-1.7	-1.8	-1.8	0.4	-1.6	-1.5	0.9	-1.6
Cardiovascular Disease	0.3	0.8	1.7	1.1	0.4	0.5	1.2	1.1	0.7	0.0	1.3	1.1
Sensitivity / hurt feelings	0.3	0.4	1.4	-0.8	-0.6	-0.6	-0.8	-0.3	-0.7	-0.1	-0.2	-1.2
Relative age of first facial hair	0.3	0.6	2.0	-0.7	0.3	0.2	-0.5	-1.3	-0.3	0.5	-1.4	-0.6
Other serious medical condition/disability diagnosed by doctor	0.3	0.4	1.1	-0.7	-0.2	-0.4	-0.7	-0.8	-0.2	-0.2	-0.9	-1.0
Eye problems/disorders: Diabetes related eye disease	0.3	0.4	0.8	0.1	0.6	0.4	0.3	-0.9	0.4	0.8	-0.9	-0.5
Pack years adult smoking proportion	0.3	0.5	1.5	0.6	0.7	0.8	0.5	-0.5	1.2	0.7	-0.4	-0.7
Current tobacco smoking	0.3	0.4	1.5	0.3	0.7	0.6	0.4	-0.7	0.1	0.8	-0.2	1.2
Relative age voice broke	0.3	0.5	0.9	-1.0	-0.6	-0.7	-0.8	-0.2	-0.9	-0.6	-0.3	-0.9
Heel bone mineral density (BMD) T-score, automated (left)	0.3	0.7	1.3	0.9	0.3	0.6	1.0	0.9	0.5	0.5	1.1	1.0
High blood pressure	0.3	0.9	1.7	1.2	0.6	0.6	1.3	0.9	0.8	0.1	1.1	1.2
Body mass index (BMI)	0.3	1.5	2.9	1.5	1.4	1.2	1.7	0.2	1.3	1.3	0.3	0.9
Waist circumference	0.3	1.1	2.1	1.5	1.0	0.9	1.4	0.5	1.1	1.0	0.6	0.9
Impedance of arm (right)	0.3	1.3	3.1	-1.3	-1.2	-1.1	-1.5	-0.1	-0.8	-0.9	-0.2	-1.8
Falls in the last year	0.3	0.4	1.2	0.9	0.6	0.6	1.1	0.2	0.6	0.2	0.3	0.3
Birth weight of first child	0.3	0.5	1.1	-0.1	-0.8	-0.8	-0.3	1.1	-0.5	-1.0	0.9	0.4
Number of full brothers	0.3	0.3	0.6	-0.6	-0.7	-0.7	-0.7	0.3	-0.5	-0.5	0.5	0.6
Pulse rate, automated reading	0.3	0.8	1.9	1.2	1.0	1.1	1.4	0.2	0.8	0.9	0.3	0.1
Had major operations	0.3	0.3	1.0	-0.6	0.0	-0.1	-0.6	-0.7	-0.3	0.2	-0.7	-1.0
Commuting to job workplace: Car/motor vehicle	0.3	0.4	0.8	-0.9	-0.4	-0.7	-0.7	-0.5	-0.8	-0.4	-0.4	-0.3
Knee pain experienced in last month	0.3	0.5	1.5	0.9	0.6	0.4	1.2	0.6	0.5	0.2	0.7	-0.6
Osteoarthritis (self-reported)	0.3	0.4	1.0	0.5	-0.1	0.1	0.3	0.6	0.4	-0.6	1.0	1.0
Average weekly champagne plus white wine intake	0.3	0.4	1.1	0.7	0.2	0.1	0.9	0.9	0.6	0.2	1.1	0.1
Commuting to job workplace: Cycle	0.3	0.4	0.7	-0.4	-0.8	-0.6	-0.5	0.7	-0.4	-0.9	0.7	0.3
Medication: Omeprazole (e.g. Zanprol)	0.3	0.4	1.9	-0.0	0.4	0.2	-0.3	-1.1	0.2	0.4	-1.4	-0.0
Bipolar Disorder (2018)	0.2	0.3	0.8	-0.7	-0.6	-0.5	-0.8	-0.1	-0.9	-0.3	0.0	0.4
Bipolar Disorder or Schizophrenia	0.2	0.6	1.8	0.1	-0.6	-0.6	0.2	1.3	-0.4	-1.0	1.3	0.1
Worry (Nagel 2018)	0.2	0.4	1.3	-0.1	-0.7	-0.5	-0.1	1.1	-0.2	-0.6	1.1	-0.1
Bipolar Disorder (2011)	0.2	0.2	0.4	0.2	0.4	0.3	0.3	-0.6	0.4	0.4	-0.3	0.6
LDL Cholesterol	0.2	0.3	1.3	0.5	0.5	0.5	0.5	0.3	0.5	0.3	0.3	1.1
Neuroticism	0.2	0.6	1.5	0.3	0.7	0.6	0.3	-1.0	0.7	1.2	-1.0	0.0
Hand grip strength (left)	0.2	0.5	2.9	0.3	0.6	0.5	0.6	-0.4	0.2	0.4	-0.5	1.7
Diabetes (mother)	0.2	0.3	0.8	0.2	-0.3	-0.3	0.4	0.9	-0.4	-0.6	0.9	-0.3
Trunk fat percentage	0.2	0.9	1.8	1.2	0.8	0.7	1.4	0.7	1.1	0.7	0.7	0.8
Average weekly fortified wine intake	0.2	0.3	1.3	-0.4	0.2	0.0	-0.2	-0.9	-0.1	0.2	-1.1	-0.5
Medication: Atenolol	0.2	0.2	0.5	-0.6	-0.4	-0.4	-0.7	-0.3	-0.4	-0.3	-0.4	-0.4
Medication: Simvastatin	0.2	0.3	1.0	0.5	-0.0	0.1	0.5	1.0	0.4	-0.2	0.9	-0.2
Arm fat percentage (right)	0.2	0.7	1.4	1.1	1.0	0.8	1.2	0.2	1.0	1.0	0.4	0.2
Frequency of tiredness / lethargy in last 2 weeks	0.2	0.4	0.7	0.3	0.7	0.7	0.3	-0.8	0.5	0.8	-0.8	-0.3
Number of live births	0.2	0.4	0.6	0.3	0.8	0.6	0.5	-0.7	0.4	0.7	-0.7	0.4
Medication: Lansoprazole	0.2	0.2	1.5	-0.2	-0.2	-0.3	-0.1	0.4	-0.3	-0.2	0.5	1.2
Tense / ‘highly strung’	0.2	0.3	0.7	-0.4	-0.8	-0.7	-0.5	0.7	-0.4	-0.7	0.6	-0.2
Hair/balding pattern: Pattern 4	0.2	0.4	0.8	-0.8	-0.3	-0.5	-0.9	-0.9	-0.7	-0.2	-0.7	-0.5
Peak expiratory flow (PEF)	0.2	0.4	2.1	0.4	0.4	0.6	0.3	-0.1	-0.1	0.8	-0.3	1.4
Medication: Ventolin 100micrograms inhaler	0.2	0.3	0.6	0.3	0.5	0.5	0.3	-0.8	0.5	0.7	-0.7	-0.1
Chronic bronchitis/emphysema (mother)	0.2	0.2	0.5	0.4	0.7	0.4	0.6	-0.4	0.5	0.4	-0.4	0.6
Body fat percentage	0.2	0.7	1.6	1.1	0.7	0.6	1.3	0.8	0.9	0.5	0.8	0.6
Leg fat percentage (right)	0.2	0.6	1.2	1.0	0.4	0.4	1.1	1.0	0.6	0.4	1.1	0.1
Comparative body size at age 10	0.2	0.5	0.9	0.9	0.8	0.9	0.9	-0.0	0.8	0.7	0.0	-0.3
Age at first live birth	0.2	0.3	0.5	0.2	0.5	0.5	0.2	-0.7	0.5	0.7	-0.7	0.1
Medication for pain relief, constipation, heartburn	0.2	0.3	1.1	0.5	0.1	0.2	0.7	0.7	0.2	-0.3	0.8	1.0
Migraine (self-reported)	0.2	0.3	1.6	0.2	0.1	0.3	0.2	0.3	0.2	0.5	0.2	-1.3
Arm fat percentage (left)	0.2	0.7	1.3	1.1	0.9	0.7	1.1	0.3	1.1	0.9	0.3	0.2
Qualifications: nursing, teaching	0.2	0.3	0.8	0.7	0.4	0.5	0.7	0.3	0.6	0.3	0.5	0.9
Medication for cholesterol	0.2	0.3	0.8	0.7	0.3	0.5	0.9	0.6	0.5	0.2	0.8	0.3
Breast cancer (self-reported)	0.2	0.3	0.6	0.7	-0.0	0.1	0.5	0.8	0.7	-0.2	0.7	0.3
Smoking status: Current	0.2	0.3	1.3	0.2	0.7	0.6	0.4	-0.7	-0.0	0.6	-0.2	1.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.2	0.5	1.0	0.9	0.8	0.7	1.0	-0.1	0.7	0.6	-0.2	0.6
Miserableness	0.2	0.3	0.6	0.7	0.3	0.6	0.8	0.7	0.4	0.3	0.8	0.3
Tinnitus: Yes, now most or all of the time	0.2	0.2	0.8	0.3	-0.0	0.1	0.3	0.6	0.0	-0.0	0.5	0.9
Irritability	0.2	0.3	1.3	-0.1	-0.6	-0.5	-0.0	0.9	-0.1	-0.3	1.1	-0.3
Diastolic blood pressure, automated reading	0.2	0.7	1.4	0.6	1.1	0.9	0.8	-0.7	1.0	1.2	-0.8	-0.2
Vascular/heart problems diagnosed by doctor	0.2	0.4	0.8	-0.8	-0.4	-0.3	-0.9	-0.8	-0.5	-0.0	-0.9	-0.7
Pack years of smoking	0.2	0.4	1.1	0.3	0.5	0.5	0.3	-0.4	1.1	0.3	-0.4	-1.0
Depressed Affect (Nagel 2018)	0.1	0.3	0.7	0.1	0.6	0.6	0.2	-0.6	0.4	0.8	-0.7	-0.3
Neuroticism (Nagel 2018)	0.1	0.2	0.7	-0.0	-0.3	-0.1	0.1	0.8	-0.2	-0.1	0.7	-0.3
Irritable Bowel Disease (IBD)	0.1	0.2	0.3	-0.2	-0.5	-0.4	-0.4	0.6	-0.3	-0.6	0.6	0.0
Waist Hip Ratio (WHR)	0.1	0.6	2.3	0.8	-0.2	0.1	0.5	1.3	-0.1	-0.2	1.5	-0.1
Systolic Blood Pressure	0.1	0.4	1.1	0.6	0.0	0.1	0.4	0.7	0.4	-0.1	0.9	1.1
Smoking Status	0.1	0.2	0.6	-0.5	0.0	0.1	-0.5	-0.8	-0.3	0.2	-0.4	0.3
Allergy or Eczema	0.1	0.4	1.0	0.8	0.5	0.6	0.8	0.2	1.0	-0.2	0.2	-0.5
Lung FVC	0.1	0.4	0.8	-0.0	0.5	0.4	0.1	-0.9	0.4	0.8	-0.9	0.5
Hair Pigment	0.1	1.8	3.0	-1.5	-1.6	-1.4	-1.7	0.4	-1.5	-1.1	0.5	-1.7
Frequency of depressed mood in last 2 weeks	0.1	0.2	0.3	0.4	0.2	0.3	0.5	0.6	0.3	0.2	0.5	0.6
Ever used hormone-replacement therapy (HRT)	0.1	0.2	0.5	-0.7	-0.2	-0.5	-0.4	-0.5	-0.5	0.1	-0.4	0.0
Systolic blood pressure, automated reading	0.1	0.2	0.7	-0.1	-0.3	-0.4	-0.1	0.5	-0.0	-0.8	0.2	-0.8
Angina	0.1	0.1	0.3	0.0	-0.3	-0.4	-0.3	0.5	0.1	-0.3	0.2	-0.3
Hand grip strength (right)	0.1	0.3	1.7	-0.3	0.0	0.1	-0.1	-0.5	-0.2	0.3	-0.8	1.3
Maternal smoking around birth	0.1	0.2	0.7	0.5	0.2	0.3	0.3	0.3	0.4	0.1	0.5	0.8
Fed-up feelings	0.1	0.3	0.5	0.5	0.6	0.6	0.6	-0.1	0.7	0.7	0.0	-0.1
Frequency of unenthusiasm / disinterest in last 2 weeks	0.1	0.2	0.8	0.4	0.4	0.3	0.6	0.2	0.0	0.4	0.2	0.9
Qualifications: CSEs or equivalent	0.1	0.1	0.3	0.4	0.3	0.5	0.4	0.3	-0.0	0.5	0.0	-0.0
Diverticular disease/diverticulitis (self-reported)	0.1	0.1	0.7	-0.3	-0.2	-0.3	-0.4	0.0	0.1	-0.1	-0.5	-0.8
Nervous feelings	0.1	0.3	0.5	-0.4	-0.7	-0.6	-0.5	0.3	-0.5	-0.6	0.3	-0.4
Hayfever/allergic rhinitis (self-reported)	0.1	0.1	0.5	-0.1	-0.1	0.1	-0.2	-0.3	-0.0	-0.2	-0.4	-0.7
Neuroticism score	0.1	0.2	0.5	0.5	0.2	0.4	0.5	0.3	0.4	0.7	0.3	0.4
Time employed in main current job	0.1	0.1	0.4	0.3	0.4	0.2	0.2	-0.6	0.4	0.4	-0.0	-0.6
Father’s age at death	0.1	0.1	0.2	0.3	0.1	0.4	0.4	0.4	0.1	-0.2	0.4	0.2
Qualifications: A levels/AS levels or equivalent	0.1	0.2	0.5	-0.0	-0.4	-0.2	0.0	0.7	0.1	-0.6	0.7	-0.4
Serious illness, injury or assault of a close relative in last 2 years	0.1	0.1	0.6	-0.2	-0.1	-0.2	-0.2	0.1	-0.2	-0.2	-0.2	-0.8
Prospective memory result	0.1	0.2	0.7	-0.3	-0.3	-0.2	-0.4	0.1	-0.6	-0.3	-0.1	-0.8
Headache pain in last month	0.1	0.3	1.2	-0.1	0.2	0.1	-0.1	-0.7	0.1	1.1	-0.7	0.2
Birth weight	0.1	0.3	0.5	0.5	0.7	0.7	0.5	-0.5	0.4	0.4	-0.4	0.5
Angina (self-reported)	0.1	0.1	0.2	-0.0	-0.4	-0.4	-0.3	0.5	-0.0	-0.3	0.2	-0.0
Medication: Ibuprofen	0.1	0.1	0.3	-0.3	-0.2	-0.3	-0.5	-0.5	-0.3	0.3	-0.3	0.1
Medication: Seretide 50 evohaler	0.1	0.1	0.3	0.1	0.2	0.3	-0.1	-0.2	0.1	0.2	-0.1	0.6
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.1	0.1	0.4	0.0	-0.2	0.0	0.0	0.4	-0.2	-0.0	0.4	0.6
Overall health rating	0.1	0.3	0.9	0.0	0.6	0.3	0.2	-0.7	0.2	0.7	-0.5	-1.0
Chest pain or discomfort	0.1	0.2	0.5	-0.2	-0.6	-0.5	-0.3	0.6	-0.2	-0.5	0.7	0.2
Age at last live birth	0.1	0.2	0.5	0.1	0.4	0.4	0.2	-0.6	0.3	0.3	-0.7	0.1
Mood swings	0.1	0.2	0.5	-0.6	-0.1	-0.2	-0.6	-0.7	-0.3	0.3	-0.6	-0.1
Long-standing illness, disability or infirmity	0.1	0.2	0.7	0.3	0.6	0.4	0.5	-0.2	0.4	0.8	-0.3	-0.0
Ever had bowel cancer screening	0.1	0.1	0.5	-0.1	-0.0	-0.2	-0.0	0.0	0.4	0.0	0.0	-0.7
Friendships satisfaction	0.1	0.2	0.6	0.2	-0.2	0.2	0.2	0.6	0.3	-0.3	0.8	-0.6
Mouth/teeth dental problems: Mouth ulcers	0.1	0.2	0.5	-0.4	-0.4	-0.4	-0.2	0.3	-0.5	-0.7	0.3	-0.5
Number of self-reported non-cancer illnesses	0.1	0.3	1.0	-0.2	0.4	0.2	-0.1	-0.7	0.2	0.5	-1.0	-0.4
Medication: Blood pressure	0.1	0.2	0.6	0.2	-0.1	-0.0	0.2	0.7	-0.2	-0.3	0.7	0.8
Leg fat percentage (left)	0.1	0.5	1.2	0.9	0.3	0.3	1.0	1.1	0.5	0.1	1.1	0.2
Pain experienced in last month	0.1	0.2	0.4	0.5	-0.0	0.2	0.4	0.6	0.3	-0.3	0.7	0.4
Depression (Nagel 2018)	0.0	0.0	0.1	-0.1	0.1	-0.1	-0.0	0.2	-0.1	0.0	0.2	0.3
Crohns Disease (2017)	0.0	0.1	0.4	0.2	0.0	-0.1	0.2	0.3	0.1	0.1	0.4	0.6
Lupus	0.0	0.1	0.2	0.3	0.2	-0.2	0.4	0.1	0.1	0.0	-0.0	0.4
Ulcerative Colitis	0.0	0.0	0.2	-0.0	0.1	0.1	-0.2	-0.1	0.0	0.0	-0.4	-0.4
Tanning	0.0	0.1	0.3	0.3	0.4	0.3	0.6	-0.1	0.3	0.3	-0.3	0.5
Alcohol usually taken with meals	0.0	0.0	0.2	-0.0	0.0	-0.1	0.1	-0.2	-0.0	-0.0	-0.0	0.5
Heart attack	0.0	0.0	0.1	0.0	-0.1	-0.0	-0.0	0.3	-0.1	-0.2	0.1	-0.2
Breastfed as a baby	0.0	0.0	0.2	-0.1	0.1	0.0	0.1	-0.1	-0.1	-0.2	-0.2	-0.5
Qualifications: O levels/GCSEs or equivalent	0.0	0.1	0.1	-0.1	-0.3	-0.2	-0.3	-0.0	0.2	-0.3	-0.0	-0.4
Mouth/teeth dental problems: Loose teeth	0.0	0.0	0.1	-0.4	-0.2	-0.2	-0.2	0.0	-0.3	-0.1	-0.1	0.0
Average weekly red wine intake	0.0	0.1	0.2	-0.3	-0.1	-0.2	-0.1	-0.1	-0.3	-0.5	-0.4	-0.2
Ever had stillbirth, spontaneous miscarriage or termination	0.0	0.0	0.1	0.2	-0.1	0.0	-0.1	0.2	-0.2	0.1	0.2	0.2
High cholesterol (Self-reported)	0.0	0.1	0.3	-0.0	-0.1	-0.1	-0.1	0.2	0.2	-0.3	-0.1	-0.5
Number of operations (self-reported)	0.0	0.1	0.2	-0.3	-0.3	-0.4	-0.2	0.3	-0.2	-0.1	0.2	0.0
Heart attack/myocardial infarction (self-reported)	0.0	0.0	0.1	0.1	-0.2	-0.0	-0.0	0.4	-0.1	-0.2	0.2	-0.0

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