Hub : Genes

NSUN4

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.2430 0.0390 0.0e+00 0.340 0.350 0.379 0.369 0.383 8.6e-43 2.7e-44 1.1e-48 4.4e-47 2.8e-49
2 GTEx Adipose Subcutaneous 0.1160 0.0390 1.8e-05 0.097 NA 0.086 NA 0.075 2.7e-08 NA 1.7e-07 NA 1.0e-06
3 GTEx Adrenal Gland 0.2367 0.0718 5.8e-05 0.182 NA 0.144 NA 0.157 4.2e-07 NA 7.7e-06 NA 2.9e-06
4 GTEx Breast Mammary Tissue 0.2020 0.0580 1.1e-05 0.145 NA 0.133 NA 0.133 6.6e-08 NA 2.5e-07 NA 2.6e-07
5 GTEx Breast Mammary Tissue (Female) 0.1114 0.0673 6.0e-02 0.059 NA 0.054 NA 0.063 7.8e-03 NA 1.1e-02 NA 6.1e-03
6 GTEx Cells EBV-transformed lymphocytes 0.4270 0.0860 1.1e-08 0.288 NA 0.301 NA 0.324 5.2e-10 NA 1.9e-10 NA 3.0e-11
7 GTEx Cells Transformed fibroblasts 0.0590 0.0280 9.9e-03 -0.001 NA 0.003 NA 0.004 4.0e-01 NA 1.8e-01 NA 1.4e-01
8 GTEx Esophagus Mucosa 0.1250 0.0380 1.1e-05 0.132 NA 0.135 NA 0.123 4.2e-09 NA 2.5e-09 NA 1.4e-08
9 GTEx Esophagus Muscularis 0.0920 0.0430 9.5e-03 0.034 NA 0.040 NA 0.035 3.8e-03 NA 1.9e-03 NA 3.3e-03
10 GTEx Heart Left Ventricle 0.1293 0.0494 9.2e-04 0.104 NA 0.092 NA 0.103 3.6e-06 NA 1.3e-05 NA 3.9e-06
11 GTEx Muscle Skeletal 0.2102 0.0455 2.8e-16 0.205 NA 0.182 NA 0.192 8.4e-20 NA 1.4e-17 NA 1.7e-18
12 GTEx Pancreas 0.1450 0.0580 2.7e-03 0.065 NA 0.092 NA 0.085 1.0e-03 NA 1.0e-04 NA 1.9e-04
13 GTEx Testis 0.2770 0.0630 2.7e-08 0.261 NA 0.241 NA 0.251 6.0e-12 NA 4.4e-11 NA 1.6e-11
14 GTEx Whole Blood 0.1980 0.0460 6.2e-13 0.178 NA 0.182 NA 0.180 3.4e-16 NA 1.4e-16 NA 2.1e-16
15 METSIM Adipose 0.0570 0.0196 1.4e-06 0.073 0.045 0.060 0.059 0.065 4.6e-11 2.3e-07 2.7e-09 3.0e-09 5.1e-10
16 NTR Blood 0.0790 0.0205 0.0e+00 0.070 0.068 0.066 0.067 0.071 1.6e-21 5.6e-21 1.6e-20 1.1e-20 6.8e-22
17 YFS Blood 0.2147 0.0309 0.0e+00 0.369 0.346 0.370 0.366 0.370 1.2e-128 9.9e-119 5.2e-129 3.7e-127 4.3e-129
18 TCGA Bladder Urothelial Carcinoma 0.1080 0.0490 5.0e-11 0.133 0.129 0.124 NA 0.136 2.4e-11 4.6e-11 1.3e-10 NA 1.4e-11
19 TCGA Breast Invasive Carcinoma 0.0800 0.0273 0.0e+00 0.156 0.163 0.163 NA 0.167 1.2e-30 3.5e-32 4.7e-32 NA 6.6e-33
20 TCGA Cervical Squamous Cell Carcinoma 0.1370 0.0610 1.1e-06 0.124 0.117 0.090 NA 0.113 1.2e-06 2.3e-06 3.4e-05 NA 3.5e-06
21 TCGA Colon Adenocarcinoma 0.1760 0.0660 4.9e-15 0.273 0.269 0.264 NA 0.267 5.0e-16 8.7e-16 1.7e-15 NA 1.1e-15
22 TCGA Esophageal Carcinoma 0.1160 0.0810 5.4e-03 0.038 0.043 0.019 NA 0.030 2.4e-02 1.6e-02 7.9e-02 NA 4.0e-02
23 TCGA Glioblastoma Multiforme 0.0760 0.0480 8.0e-03 0.041 0.060 0.014 NA 0.053 2.2e-02 7.0e-03 1.2e-01 NA 1.0e-02
24 TCGA Head and Neck Squamous Cell Carcinoma 0.0607 0.0293 2.4e-09 0.091 0.084 0.070 NA 0.086 2.2e-10 1.2e-09 2.5e-08 NA 7.4e-10
25 TCGA Kidney Renal Clear Cell Carcinoma 0.0911 0.0389 6.5e-14 0.141 0.137 0.127 NA 0.138 1.3e-15 4.0e-15 3.9e-14 NA 2.7e-15
26 TCGA Kidney Renal Papillary Cell Carcinoma 0.0660 0.0390 2.2e-04 0.084 0.047 0.022 NA 0.056 1.5e-05 1.1e-03 1.9e-02 NA 3.9e-04
27 TCGA Brain Lower Grade Glioma 0.0528 0.0256 1.1e-06 0.047 0.052 0.053 NA 0.052 4.7e-06 1.5e-06 1.1e-06 NA 1.3e-06
28 TCGA Liver Hepatocellular Carcinoma 0.1300 0.0580 1.1e-06 0.139 0.149 0.124 NA 0.133 4.6e-07 1.7e-07 1.9e-06 NA 7.8e-07
29 TCGA Lung Adenocarcinoma 0.0480 0.0253 2.0e-07 0.062 0.053 0.054 NA 0.057 8.2e-08 7.0e-07 5.8e-07 NA 2.8e-07
30 TCGA Lung Squamous Cell Carcinoma 0.0783 0.0297 0.0e+00 0.182 0.171 0.176 NA 0.180 3.3e-20 5.6e-19 1.6e-19 NA 5.9e-20
31 TCGA Ovarian Serous Cystadenocarcinoma 0.0400 0.0240 2.6e-03 0.045 0.039 0.035 NA 0.037 5.4e-04 1.2e-03 2.1e-03 NA 1.5e-03
32 TCGA Pancreatic Adenocarcinoma 0.1670 0.0690 1.5e-09 0.195 0.189 0.181 NA 0.190 1.3e-08 2.2e-08 4.6e-08 NA 2.0e-08
33 TCGA Prostate Adenocarcinoma 0.1480 0.0471 0.0e+00 0.315 0.304 0.320 NA 0.318 1.4e-33 3.2e-32 4.1e-34 NA 6.1e-34
34 TCGA Rectum Adenocarcinoma 0.2510 0.1190 3.3e-04 0.140 0.115 0.114 NA 0.095 3.7e-04 1.2e-03 1.3e-03 NA 3.1e-03
35 TCGA Stomach Adenocarcinoma 0.0960 0.0480 3.5e-07 0.049 0.091 0.072 NA 0.084 1.8e-04 4.0e-07 7.0e-06 NA 1.1e-06
36 TCGA Thyroid Carcinoma 0.1570 0.0510 0.0e+00 0.294 0.303 0.298 NA 0.308 6.4e-29 6.6e-30 2.6e-29 NA 1.8e-30
37 TCGA Uterine Corpus Endometrial Carcinoma 0.1290 0.0980 7.2e-03 0.073 0.021 0.021 NA 0.035 4.4e-03 8.2e-02 8.2e-02 NA 3.8e-02

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37
Bipolar Disorder (2018) 7.1 11.2 17.7 2.8 2.8 3.0 3.5 3.3 3.3 -0.6 3.6 3.6 3.3 3.2 4.2 -3.8 -3.1 3.5 -3.2 -3.3 3.9 3.6 3.6 3.3 3.7 3.5 3.3 3.4 3.5 2.6 3.4 3.4 3.4 3.5 3.4 3.4 3.2 4.0 3.4 2.8
Bipolar Disorder or Schizophrenia 1.4 3.5 6.8 1.4 1.5 1.9 2.0 1.9 1.8 -0.1 2.1 1.6 2.3 2.0 2.6 -1.9 -1.7 2.1 -1.8 -1.8 2.1 1.9 2.0 1.9 2.0 1.9 1.9 2.0 1.9 1.4 1.7 2.0 2.0 1.9 1.8 1.9 1.8 2.0 1.9 1.5
Depressed Affect (Nagel 2018) 0.9 1.9 3.2 1.6 1.3 1.2 1.5 1.5 1.5 0.8 1.5 0.6 1.4 1.5 0.6 -1.3 -1.5 1.6 -1.5 -1.5 1.3 1.4 1.4 1.4 1.0 1.3 1.6 1.8 1.5 1.1 1.3 1.4 1.6 1.4 1.4 1.5 1.6 0.8 1.7 0.9
Depression (Nagel 2018) 0.6 1.0 1.9 1.2 1.2 1.3 0.9 1.0 1.1 0.9 0.9 -0.1 1.3 1.3 -0.1 -0.8 -1.2 1.0 -1.4 -1.0 0.9 0.9 1.1 1.1 0.6 0.8 1.0 1.0 0.9 1.1 0.7 0.9 1.1 0.8 1.0 1.0 1.1 0.4 1.1 0.9
Intelligence (Savage-Jansen 2018) 0.0 0.1 1.0 -0.6 0.0 -0.0 -0.0 -0.1 -0.1 -1.0 -0.5 0.7 -0.1 -0.1 0.4 -0.2 0.4 -0.1 -0.1 0.1 0.6 0.0 0.0 -0.0 0.5 0.2 -0.2 0.3 0.0 -0.8 -0.3 -0.1 -0.0 -0.0 -0.2 -0.0 -0.1 0.7 0.1 -0.5
Neuroticism (Nagel 2018) 0.1 0.2 0.6 0.8 0.4 0.6 0.4 0.5 0.5 0.4 0.8 -0.1 0.3 0.4 -0.0 -0.5 -0.5 0.5 -0.6 -0.4 0.3 0.3 0.5 0.7 0.2 0.3 0.6 0.8 0.4 0.3 0.5 0.5 0.5 0.3 0.4 0.5 0.7 -0.0 0.6 0.4
Schizophrenia (2018) 0.1 0.1 0.8 -0.4 -0.4 0.0 -0.2 -0.3 -0.4 0.4 -0.2 -0.9 0.2 -0.1 0.2 0.5 0.4 -0.1 0.3 0.4 -0.5 -0.4 -0.3 -0.2 -0.5 -0.4 -0.3 -0.2 -0.4 -0.3 -0.5 -0.2 -0.2 -0.5 -0.4 -0.4 -0.3 -0.7 -0.3 -0.4
Schizophrenia vs Biploar Disorder 2.3 3.1 7.7 -1.0 -1.2 -1.2 -1.7 -1.7 -1.5 0.4 -2.1 -2.8 -1.3 -1.3 -2.7 2.1 1.4 -1.6 1.4 1.6 -2.3 -2.1 -2.0 -1.5 -2.0 -1.9 -1.6 -2.0 -1.8 -0.6 -1.6 -1.7 -1.7 -2.0 -1.7 -1.8 -1.4 -2.6 -1.7 -1.0
Worry (Nagel 2018) 0.0 0.0 0.3 -0.1 -0.1 0.2 -0.1 -0.1 -0.1 0.0 0.2 0.3 -0.4 -0.2 -0.2 -0.1 -0.1 -0.1 0.0 0.1 -0.3 -0.0 0.3 0.2 0.1 0.0 -0.1 0.2 -0.1 -0.6 0.0 -0.1 -0.0 -0.2 -0.1 -0.0 -0.2 -0.1 0.0 -0.4
Alzheimer’s Disease (in mother) 0.1 0.1 1.4 -0.1 -0.2 -0.3 -0.2 -0.2 -0.3 -1.2 -0.4 -0.2 -0.0 -0.0 0.2 0.1 0.4 -0.2 -0.0 0.3 -0.3 -0.3 -0.3 -0.2 -0.2 -0.2 -0.3 -0.0 -0.5 0.0 -0.3 -0.0 -0.2 -0.2 -0.2 -0.2 -0.2 -0.2 -0.2 0.2
Alzheimer’s Disease (in father) 1.7 1.9 3.5 1.3 1.5 1.1 1.6 1.4 1.3 0.1 1.0 1.0 1.4 1.4 1.7 -1.0 -1.3 1.4 -1.9 -1.4 1.3 1.5 1.6 1.5 1.3 1.5 1.4 1.3 1.6 1.3 1.3 1.3 1.3 1.3 1.4 1.4 1.1 1.3 1.3 1.6
Alzheimer’s Disease (including proxy) 0.2 0.3 2.2 0.6 0.5 0.1 0.5 0.4 0.2 -1.5 0.1 -0.1 0.5 0.5 1.4 -0.3 -0.2 0.4 -0.9 -0.3 0.3 0.4 0.4 0.5 0.2 0.4 0.4 0.4 0.2 0.7 0.3 0.5 0.4 0.3 0.5 0.4 0.3 0.2 0.2 1.0
Crohns Disease (2017) 0.5 1.0 1.8 1.1 1.4 1.2 0.9 1.0 1.0 1.1 0.7 0.2 1.2 1.1 0.8 -1.0 -1.3 1.1 -0.9 -1.0 1.0 0.9 0.8 0.9 0.8 0.8 1.3 0.9 1.0 1.2 1.0 1.1 1.0 1.0 1.0 1.1 1.2 0.7 0.9 0.9
Irritable Bowel Disease (IBD) 1.9 4.6 8.0 2.5 2.8 2.3 2.3 2.3 2.2 1.9 1.8 0.8 2.2 2.4 1.8 -2.0 -2.2 2.3 -2.2 -2.2 1.9 2.0 1.7 2.2 1.6 1.9 2.6 2.3 2.2 2.3 2.0 2.4 2.3 2.0 2.2 2.3 2.7 1.1 2.2 2.0
Ulcerative Colitis (UC) 2.8 5.2 9.1 2.9 3.0 2.2 2.5 2.5 2.3 1.9 2.0 0.9 2.1 2.6 1.7 -2.0 -2.2 2.4 -2.5 -2.3 1.9 2.2 1.8 2.4 1.6 2.1 2.8 2.5 2.4 2.5 2.1 2.5 2.4 2.2 2.3 2.4 2.9 0.9 2.4 2.4
Major Depression (MDD) 0.1 0.1 1.0 0.3 0.1 -0.8 0.0 0.2 0.0 -1.0 0.1 0.1 -0.3 0.2 0.4 0.0 0.3 -0.0 -0.1 -0.1 0.1 0.1 0.0 0.1 0.1 0.0 0.0 -0.3 0.0 0.5 0.1 -0.1 -0.1 0.0 0.2 0.0 0.0 0.2 -0.1 0.6
Reaction Time 1.0 1.9 2.7 1.4 0.6 1.3 1.6 1.5 1.4 -0.8 1.1 0.5 1.3 1.5 1.3 -1.4 -1.6 1.6 -1.5 -1.5 1.0 1.5 1.4 1.6 1.3 1.6 1.5 1.6 1.5 1.1 1.4 1.5 1.5 1.4 1.6 1.5 1.5 0.9 1.5 1.2
Verbal and Numeric Reasoning (VNR) 0.8 1.8 4.7 -1.8 -1.0 -1.4 -1.3 -1.4 -1.4 -0.6 -2.2 0.0 -1.3 -1.3 -1.5 1.4 1.5 -1.4 1.1 1.4 -0.8 -1.3 -1.1 -1.2 -0.7 -1.0 -1.4 -1.1 -1.2 -1.9 -1.7 -1.4 -1.4 -1.4 -1.4 -1.3 -1.5 -0.7 -1.3 -2.0
Breast Cancer 7.4 17.9 22.0 4.5 4.1 4.5 4.6 4.5 4.3 2.2 4.5 2.0 4.5 4.7 3.3 -4.4 -4.3 4.5 -4.4 -4.4 4.2 4.3 3.9 4.4 4.1 4.4 4.5 4.5 4.5 4.0 3.9 4.6 4.4 4.3 4.5 4.4 4.7 3.4 4.5 3.7
Ovarian Cancer 0.0 0.0 0.2 -0.1 0.2 -0.1 0.1 -0.1 0.1 0.2 -0.3 -0.1 -0.1 -0.1 -0.1 -0.0 0.2 -0.0 0.3 -0.0 -0.1 -0.2 -0.2 -0.1 -0.1 -0.2 -0.1 -0.0 -0.1 -0.2 -0.1 0.1 0.0 -0.2 -0.1 -0.1 0.1 -0.4 0.1 -0.5
Prostate Cancer 4.4 6.2 9.3 -2.1 -2.4 -2.1 -2.5 -2.5 -2.5 -1.3 -2.4 -2.6 -2.5 -2.5 -1.5 2.7 2.1 -2.4 2.3 2.5 -2.9 -2.7 -2.7 -2.7 -3.0 -2.7 -2.5 -2.6 -2.5 -2.4 -2.6 -2.6 -2.5 -2.5 -2.5 -2.6 -2.3 -3.0 -2.5 -2.3
Age at First Birth 1.6 2.3 6.0 1.1 1.5 2.3 1.6 1.4 1.5 0.5 1.5 2.5 1.2 1.6 1.5 -1.6 -1.8 1.4 -1.4 -1.4 1.6 1.6 1.6 1.5 1.8 1.7 1.4 1.5 1.5 1.2 1.2 1.4 1.4 1.5 1.4 1.5 1.2 1.7 1.5 1.0
Bipolar Disorder (2011) 3.8 3.6 4.6 1.7 1.6 1.9 2.0 2.0 2.1 -0.4 2.0 1.4 2.1 2.0 1.3 -1.9 -2.0 2.1 -2.0 -2.0 2.1 2.0 2.0 2.0 2.0 2.1 2.0 2.1 2.0 1.6 1.7 2.1 2.1 2.0 2.0 2.0 1.9 1.8 2.2 1.5
Body Mass Index (BMI) (2010) 1.4 1.9 3.1 1.1 1.0 1.0 1.3 1.4 1.5 0.8 1.7 0.9 1.6 1.2 1.2 -1.5 -1.4 1.4 -1.6 -1.5 1.8 1.5 1.3 1.2 1.4 1.5 1.4 1.5 1.4 1.3 1.5 1.4 1.5 1.6 1.4 1.5 1.3 1.6 1.6 1.3
Coronary Artery Disease (CAD) 0.2 0.2 1.6 0.0 0.5 0.3 0.2 0.5 0.3 -0.5 0.4 1.3 -0.0 0.4 0.8 -0.8 -0.3 0.2 -0.1 -0.4 0.5 0.5 0.4 0.2 0.5 0.4 0.3 0.1 0.5 -0.3 0.5 0.2 0.4 0.6 0.5 0.4 0.0 0.7 0.2 0.2
Crohns Disease (2012) 0.3 0.5 4.0 1.2 0.7 0.9 0.2 0.5 0.6 2.0 0.3 -0.9 0.9 0.5 -1.0 -0.3 -0.7 0.5 -0.3 -0.6 0.0 0.1 -0.1 0.4 -0.2 0.0 0.5 -0.0 0.3 1.4 0.4 0.6 0.5 0.2 0.6 0.4 0.9 -0.6 0.3 0.8
Mean Putamen Volume 0.2 0.2 1.7 -0.4 -1.1 -0.4 -0.6 -0.5 -0.6 -1.3 -0.5 0.3 -0.4 -0.5 0.5 0.3 0.4 -0.4 0.3 0.5 -0.3 -0.3 -0.2 -0.4 0.0 -0.3 -0.4 -0.6 -0.3 -0.0 -0.0 -0.3 -0.4 -0.2 -0.5 -0.4 -0.6 0.3 -0.6 0.2
Fasting Glucose 0.6 0.7 1.6 -1.0 -0.9 -0.9 -0.9 -1.0 -0.9 -0.5 -0.7 0.0 -1.0 -1.1 -0.2 1.0 0.7 -1.0 0.9 1.0 -0.9 -0.7 -0.6 -0.9 -0.7 -0.8 1.3 -0.8 -1.0 -0.9 -0.6 -0.9 -0.9 -0.6 -1.0 -0.2 -1.1 -0.4 -0.9 -1.0
HbA1C 0.8 0.8 3.8 -0.2 -0.6 -0.5 -0.9 -0.9 -0.9 -0.2 -0.2 -0.6 -1.0 -1.0 -2.0 0.6 1.0 -0.9 1.2 0.9 -0.8 -1.1 -1.2 -0.9 -0.7 -1.3 -0.9 -1.7 -1.0 0.6 -0.2 -0.8 -0.9 -0.9 -0.9 -1.0 -0.3 -0.8 -1.3 0.1
HDL Cholesterol 2.8 4.6 8.1 2.0 2.7 2.1 1.7 2.0 2.1 2.0 2.8 2.0 1.9 2.1 2.4 -2.4 -2.2 2.1 -2.2 -2.1 2.1 2.1 2.1 2.1 2.2 2.0 2.1 2.2 2.1 2.0 2.1 2.2 2.2 2.2 2.1 2.1 2.1 2.2 2.2 2.0
LDL Cholesterol 1.1 1.8 3.7 -1.5 -0.9 -1.8 -1.2 -1.4 -1.5 -0.2 -1.9 -0.5 -1.0 -1.2 -1.7 1.5 1.1 -1.4 1.2 1.5 -1.7 -1.3 -1.5 -1.5 -1.3 -1.2 -1.4 -1.3 -1.4 -0.9 -1.3 -1.3 -1.3 -1.1 -1.5 -1.4 -1.7 -1.0 -1.5 -1.0
Lupus 0.4 0.5 4.2 0.7 0.6 0.3 0.4 0.7 0.9 2.1 0.5 0.2 0.6 0.8 -0.6 -0.5 -0.7 0.8 -0.8 -0.8 0.7 0.6 0.5 0.7 0.4 0.7 0.7 1.0 0.7 0.5 0.4 0.8 0.9 0.6 0.6 0.7 0.9 0.2 1.0 0.5
Neuroticism (2016) 1.3 1.8 3.3 1.6 1.3 1.8 1.5 1.3 1.2 -0.4 1.7 0.4 1.1 1.4 1.2 -1.5 -1.5 1.4 -1.4 -1.3 1.0 1.2 1.2 1.5 1.3 1.2 1.4 1.3 1.4 1.6 1.7 1.4 1.4 1.3 1.3 1.3 1.5 1.0 1.2 1.6
Primary Biliary Cirrhosis 0.5 0.7 1.4 -0.8 -0.6 -0.8 -1.2 -0.8 -0.9 -0.7 -0.9 0.3 -0.7 -0.9 -0.6 0.7 1.1 -0.9 0.9 0.8 -0.7 -0.9 -0.9 -0.9 -0.8 -0.9 -0.8 -0.9 -0.8 -0.9 -0.8 -0.9 -0.9 -0.8 -0.8 -0.9 -0.7 -0.7 -0.9 -0.7
Rheumatoid Arthritis 1.7 2.4 6.0 -1.6 -1.5 -1.6 -1.5 -1.6 -1.7 -2.5 -1.4 -0.7 -2.0 -1.9 -0.3 1.0 1.7 -1.6 2.0 1.6 -1.2 -1.5 -1.7 -1.8 -1.1 -1.5 -1.6 -1.6 -1.5 -1.3 -1.2 -1.6 -1.6 -1.3 -1.6 -1.6 -1.4 -0.8 -1.7 -1.4
Schizophrenia (2014) 0.0 0.1 0.5 0.2 0.0 0.5 0.3 0.1 0.0 -0.6 0.2 -0.5 0.7 0.3 0.7 -0.0 -0.1 0.2 -0.2 -0.0 -0.2 0.0 0.1 0.4 0.2 0.1 0.2 -0.0 0.1 0.5 0.2 0.2 0.1 -0.0 0.0 0.1 0.2 -0.1 0.0 0.5
Triglycerides 0.5 0.8 1.5 -0.8 -0.8 -1.0 -0.9 -0.9 -0.9 -0.6 -1.2 -0.4 -0.7 -0.9 -1.2 1.0 1.2 -1.0 0.7 0.9 -0.9 -0.9 -0.8 -0.8 -0.9 -0.8 -0.9 -1.0 -1.0 -0.9 -0.9 -0.8 -0.9 -1.0 -0.9 -0.9 -1.0 -1.1 -1.0 -0.8
Type 2 Diabetes (T2D) (2012) 0.2 0.2 1.3 -0.6 0.2 -0.9 -0.3 -0.4 -0.5 -1.1 -0.1 1.1 -0.5 -0.4 0.5 0.4 0.4 -0.4 0.1 0.4 -0.4 -0.3 -0.1 -0.3 -0.3 -0.2 -0.4 -0.1 -0.4 -0.9 -0.4 -0.4 -0.4 -0.4 -0.4 -0.4 -0.6 -0.2 -0.3 -0.2
Ulcerative Colitis 1.6 2.3 3.6 1.9 1.8 1.5 1.7 1.7 1.5 1.4 1.2 0.9 1.7 1.8 0.5 -1.2 -1.5 1.7 -1.5 -1.6 1.3 1.5 1.3 1.6 1.1 1.4 1.8 1.7 1.6 1.7 1.3 1.7 1.6 1.5 1.7 1.6 1.9 0.7 1.6 1.4
Blood Eosinophil Count 1.2 9.5 29.2 -0.9 -3.1 -2.4 -3.2 -2.8 -2.5 0.1 -2.6 -5.4 -2.4 -2.9 -4.2 3.5 2.8 -2.9 2.6 2.7 -3.5 -3.6 -4.0 -3.2 -4.5 -3.8 -2.9 -3.9 -3.0 -0.5 -2.3 -2.9 -2.8 -3.1 -2.8 -3.1 -1.9 -4.6 -3.2 -0.3
Blood Platelet Count 0.2 2.4 4.7 -2.0 -1.6 -0.8 -2.0 -1.7 -1.5 -1.6 -0.5 -1.4 -2.1 -1.6 0.9 1.6 0.6 -1.7 1.4 1.6 -1.7 -1.4 -1.4 -2.0 -1.9 -1.6 -1.7 -1.5 -1.3 -1.3 -1.5 -1.6 -1.6 -1.1 -1.7 -1.5 -2.2 -1.1 -1.5 -1.5
Blood Red Count 0.4 3.5 33.6 3.2 -0.3 2.6 0.2 0.2 0.4 1.4 -1.2 -5.2 0.9 0.3 -5.8 1.1 -0.2 0.2 0.2 -0.2 -1.5 -1.4 -1.3 0.3 -2.1 -1.6 0.2 -1.1 -0.4 2.9 0.5 0.3 0.2 -1.1 0.2 -0.5 1.9 -3.9 -0.3 1.9
Blood White Count 1.4 10.1 18.4 -2.2 -3.8 -2.6 -3.1 -3.1 -2.8 -1.0 -3.9 -4.3 -3.0 -3.0 -4.0 3.5 2.5 -3.0 3.1 2.9 -4.1 -3.4 -3.2 -3.1 -4.1 -3.4 -3.0 -3.3 -3.2 -2.3 -2.8 -3.0 -3.0 -3.2 -3.0 -3.1 -2.9 -4.2 -3.1 -2.3
Heel T-Score 1.3 10.3 17.5 -2.2 -4.2 -2.7 -3.0 -3.3 -3.1 -4.1 -2.9 -3.8 -3.0 -3.4 -2.8 2.9 3.5 -3.3 3.7 3.2 -2.8 -3.5 -3.5 -3.3 -3.1 -3.6 -3.2 -4.1 -3.0 -1.6 -2.5 -3.3 -3.3 -3.2 -3.3 -3.4 -2.5 -3.0 -3.6 -1.8
BMI 0.5 3.0 6.2 -2.0 -2.1 -2.5 -2.0 -2.0 -1.9 -1.7 -1.2 -1.5 -1.6 -1.9 0.4 1.6 1.9 -1.9 1.8 1.9 -1.3 -1.7 -2.0 -2.2 -1.6 -1.7 -1.9 -2.2 -1.1 -1.0 -1.5 -1.8 -1.8 -1.3 -2.0 -1.8 -2.0 -1.0 -2.0 -0.7
Height 0.2 3.2 14.6 2.7 1.5 3.8 1.9 1.8 1.8 -0.7 2.0 -0.5 1.6 1.9 1.1 -1.8 -2.0 1.7 -1.5 -1.8 1.2 1.4 1.2 1.9 1.6 1.4 1.7 1.2 1.4 2.6 1.9 1.7 1.7 1.4 1.9 1.6 2.2 0.9 1.5 2.5
Waist Hip Ratio (WHR) 0.1 0.5 2.8 -1.1 -1.3 -0.4 -0.6 -0.5 -0.5 -1.7 -1.2 0.1 -0.2 -0.8 -1.1 0.5 0.5 -0.6 0.8 0.5 -0.1 -0.3 -0.2 -0.6 -0.2 -0.3 -0.6 -0.5 -0.5 -1.2 -0.5 -0.6 -0.6 -0.4 -0.6 -0.4 -0.9 0.3 -0.5 -0.6
Systolic Blood Pressure 0.7 3.4 7.5 -2.5 -2.0 -1.0 -2.0 -1.9 -1.9 -2.7 -1.4 -0.2 -2.4 -1.7 1.3 1.6 1.3 -1.9 1.9 1.9 -1.6 -1.5 -1.5 -2.0 -1.2 -1.5 -1.9 -1.6 -1.8 -2.4 -2.2 -2.1 -2.0 -1.6 -1.9 -1.8 -2.3 -0.8 -1.9 -2.6
Smoking Status 0.3 0.8 10.0 -1.6 -1.7 -0.9 -0.7 -0.9 -0.4 -3.2 -0.5 0.2 -0.8 -0.9 0.8 0.2 0.2 -0.8 0.6 0.6 0.1 -0.2 -0.2 -0.9 0.1 -0.2 -0.7 -0.5 -0.5 -1.0 -0.5 -0.9 -0.6 0.0 -0.8 -0.4 -1.4 1.0 -0.4 -0.8
Allergy or Eczema 0.1 0.2 1.1 -0.7 0.3 -0.7 -0.2 -0.3 -0.7 1.1 -0.4 0.1 -0.3 -0.2 -0.9 0.5 0.7 -0.4 0.6 0.5 -0.2 -0.4 -0.5 -0.5 -0.4 -0.4 -0.3 -0.0 -0.5 -0.7 -0.8 -0.3 -0.5 -0.5 -0.4 -0.4 -0.3 -0.2 -0.4 -0.7
Cardiovascular Disease 0.5 1.6 7.6 -0.8 -1.7 0.7 -1.2 -1.3 -1.1 -2.8 -0.3 -2.2 -1.5 -0.9 0.4 1.1 0.5 -1.2 1.2 1.2 -1.4 -1.2 -1.5 -1.3 -1.2 -1.2 -1.2 -1.3 -1.4 -0.6 -1.4 -1.1 -1.2 -1.1 -1.2 -1.2 -1.0 -1.4 -1.2 -0.8
Hypothyroidism (self reported) 3.8 8.7 12.9 -2.8 -3.2 -3.5 -3.3 -3.1 -3.0 -2.3 -2.5 -1.9 -2.9 -3.1 -2.1 2.5 3.6 -3.2 3.3 3.1 -2.4 -3.0 -3.1 -3.2 -2.7 -3.1 -3.2 -3.3 -2.9 -2.2 -2.9 -3.1 -3.2 -2.9 -3.2 -3.1 -2.8 -2.3 -3.2 -2.6
Respiratory disease 2.2 4.8 8.4 2.0 1.6 2.3 2.3 2.2 1.9 0.6 2.9 1.9 2.3 2.1 2.2 -2.6 -2.1 2.2 -1.8 -2.1 2.3 2.3 2.3 2.1 2.4 2.1 2.2 2.0 2.2 2.3 2.5 2.2 2.1 2.4 2.2 2.2 2.1 2.7 1.9 2.4
Type 2 Diabetes (T2D) (2018) 3.6 6.8 10.4 -2.7 -3.2 -2.3 -3.0 -2.8 -2.8 -1.9 -2.5 -1.7 -2.7 -2.8 -1.3 2.6 2.7 -2.9 2.8 2.8 -2.5 -2.5 -2.6 -2.8 -2.3 -2.5 -2.9 -2.8 -2.4 -2.2 -2.5 -2.8 -2.8 -2.5 -2.9 -2.8 -3.0 -2.0 -2.9 -2.2
Lung FEV1/FVC ratio 0.8 3.9 14.7 0.9 2.4 1.3 1.4 1.8 2.3 1.3 2.0 2.2 1.2 2.0 3.8 -2.1 -2.2 1.8 -1.8 -2.1 2.4 2.2 2.4 1.7 2.0 2.2 1.8 2.4 2.0 0.8 1.2 1.9 2.0 2.2 1.8 2.1 1.2 2.3 2.5 0.3
Lung FVC 0.3 1.6 3.5 -0.8 -1.1 -1.9 -1.2 -1.1 -1.0 -0.7 -1.9 -1.5 -1.2 -1.0 -1.8 1.2 1.1 -1.2 0.9 1.0 -1.6 -1.2 -0.9 -1.0 -1.6 -1.3 -1.2 -0.7 -1.4 -1.3 -1.2 -1.3 -1.1 -1.4 -1.0 -1.2 -1.0 -1.7 -0.8 -1.5
Neuroticism 0.1 0.2 1.7 0.8 0.1 0.9 0.4 0.2 0.3 0.3 0.6 -1.3 0.1 0.4 -0.4 -0.1 -0.4 0.3 -0.4 -0.2 -0.0 -0.1 -0.1 0.3 -0.3 -0.1 0.3 0.3 0.5 0.6 0.1 0.3 0.3 -0.1 0.1 0.1 0.7 -0.8 0.3 0.3
Chronotype (morning person) 0.3 0.7 2.6 0.9 0.4 0.7 0.6 0.7 0.8 -1.0 1.1 0.2 0.5 0.7 0.6 -1.1 -0.8 0.7 -1.1 -0.8 0.8 0.7 0.4 0.7 0.8 0.7 0.7 0.6 0.7 1.1 1.0 0.8 0.8 0.9 0.7 0.7 1.0 1.0 0.7 1.6
Hair Pigment 0.0 0.2 2.9 -0.3 0.4 -0.0 0.4 0.3 0.3 -0.4 0.0 0.1 0.1 0.3 1.7 -0.5 -0.4 0.4 -0.0 -0.3 0.4 0.4 0.6 0.1 0.1 0.3 0.4 0.8 0.1 -0.6 -0.0 0.3 0.3 0.4 0.3 0.4 0.1 0.7 0.6 -0.6
Tanning 0.3 3.5 5.4 2.1 1.9 1.8 1.8 1.8 1.9 1.6 1.8 0.9 2.0 1.8 1.8 -2.3 -1.7 1.9 -1.7 -1.9 1.8 1.7 1.6 1.9 2.0 1.7 1.9 1.6 1.8 2.2 2.2 1.9 1.8 1.9 1.8 1.8 2.3 1.7 1.8 2.2
Hand grip strength (left) 0.2 0.6 2.4 1.6 0.6 0.8 0.8 0.7 0.7 -1.1 1.0 -1.0 0.3 0.7 0.4 -0.7 -0.2 0.6 -0.7 -0.7 0.5 0.3 0.1 0.7 0.3 0.2 0.7 0.3 0.6 1.6 0.8 0.6 0.7 0.4 0.7 0.5 1.4 -0.0 0.5 1.6
Number of treatments/medications taken 0.1 0.1 2.1 -0.1 -0.4 0.2 -0.2 -0.0 -0.1 -1.4 0.4 0.2 0.1 -0.1 0.7 -0.2 0.2 0.0 -0.2 0.0 0.4 0.1 0.2 0.2 0.5 0.1 -0.0 -0.1 0.2 0.2 0.3 0.1 0.0 0.1 -0.0 0.0 0.1 0.5 -0.0 0.6
Average weekly spirits intake 3.4 4.2 6.2 -1.6 -2.1 -2.5 -2.3 -2.1 -2.3 -0.9 -2.4 -1.6 -1.8 -2.0 -1.6 2.2 2.5 -2.1 1.9 2.2 -2.1 -2.3 -2.2 -2.1 -2.2 -2.3 -2.1 -2.3 -2.1 -1.0 -1.9 -2.0 -2.1 -2.1 -2.1 -2.2 -1.8 -2.1 -2.4 -0.9
Sensitivity / hurt feelings 0.5 0.8 1.8 -0.7 -1.0 -0.6 -0.9 -1.1 -0.8 -1.2 -0.3 -1.4 -0.9 -1.2 0.1 0.7 0.8 -1.0 0.6 0.9 -1.0 -1.2 -1.1 -0.8 -0.9 -1.1 -1.0 -1.0 -0.7 -0.9 -0.7 -0.8 -0.9 -1.1 -1.1 -1.0 -0.6 -1.2 -0.9 -0.7
Frequency of depressed mood in last 2 weeks 0.0 0.0 0.2 -0.2 0.4 0.2 -0.2 -0.1 0.1 0.5 0.1 0.4 0.3 0.1 0.2 -0.3 -0.2 -0.1 -0.3 0.0 0.1 -0.0 0.2 0.1 0.2 -0.0 -0.1 0.1 0.1 -0.1 -0.0 -0.2 0.0 -0.0 -0.1 -0.1 -0.1 0.3 0.1 -0.1
Hearing difficulty/problems: Yes 2.4 3.7 9.1 2.7 1.6 3.0 1.9 2.0 2.0 2.1 2.4 -0.0 2.1 2.2 -0.2 -1.9 -2.0 2.1 -1.5 -2.0 1.2 1.5 1.4 2.1 1.4 1.5 2.1 1.3 1.4 2.8 2.0 2.0 2.0 1.5 2.0 1.8 2.6 0.4 1.8 2.3
Relative age of first facial hair 0.0 0.1 0.7 0.0 -0.2 0.0 0.0 -0.2 -0.1 -0.9 -0.1 -0.8 -0.2 -0.3 -0.6 0.5 0.1 -0.1 0.0 0.1 -0.3 -0.3 0.1 0.0 -0.4 -0.3 -0.1 -0.1 -0.0 -0.2 0.0 -0.0 -0.1 -0.4 -0.2 -0.1 -0.2 -0.5 -0.1 -0.1
Other serious medical condition/disability diagnosed by doctor 0.2 0.3 1.3 0.1 -0.9 -0.0 -0.6 -0.5 -0.4 -0.5 -0.1 -1.1 -0.4 -0.4 0.5 0.1 0.9 -0.4 0.2 0.5 -0.0 -0.6 -0.7 -0.3 -0.4 -0.6 -0.5 -0.7 -0.5 0.3 -0.3 -0.5 -0.4 -0.6 -0.5 -0.6 0.0 -0.6 -0.5 0.3
Ever used hormone-replacement therapy (HRT) 0.5 0.7 1.3 1.0 1.1 1.1 1.0 0.9 0.9 0.2 0.8 0.0 0.6 0.8 0.5 -0.9 -0.8 0.8 -0.8 -0.9 0.5 0.7 0.8 1.0 0.7 0.7 0.9 0.4 0.5 1.0 1.0 0.9 0.9 0.7 0.9 0.8 1.1 0.2 0.7 1.1
Ever had hysterectomy (womb removed) 0.2 0.2 1.0 -0.2 -0.4 -0.3 -0.4 -0.5 -0.6 -0.8 -0.5 -0.2 -0.6 -0.6 0.3 0.3 0.8 -0.5 0.6 0.6 -0.1 -0.4 -0.4 -0.4 -0.0 -0.4 -0.5 -1.0 -0.4 0.4 -0.0 -0.4 -0.6 -0.4 -0.5 -0.5 -0.4 -0.0 -0.8 0.4
Systolic blood pressure, automated reading 1.9 5.5 9.0 -2.9 -2.5 -1.9 -2.4 -2.5 -2.6 -3.0 -2.3 -0.9 -2.7 -2.4 0.3 2.1 2.2 -2.5 2.6 2.5 -2.1 -2.2 -2.2 -2.6 -1.8 -2.1 -2.5 -2.5 -2.1 -2.5 -2.5 -2.7 -2.7 -2.1 -2.5 -2.4 -2.7 -1.3 -2.6 -2.5
Eye problems/disorders: Diabetes related eye disease 0.3 0.4 1.8 -0.6 -1.0 -0.1 -0.6 -0.6 -0.4 -0.9 -0.5 -1.3 -0.4 -0.5 0.4 0.5 0.2 -0.6 0.8 0.5 -0.6 -0.5 -0.6 -0.7 -0.5 -0.6 -0.5 -0.4 -0.7 -0.4 -0.6 -0.4 -0.5 -0.5 -0.5 -0.5 -0.5 -0.3 -0.4 -0.8
Angina 0.0 0.0 0.2 0.2 -0.2 0.0 -0.3 -0.1 0.1 -0.1 0.1 -0.4 -0.2 -0.0 -0.3 0.1 0.2 -0.1 0.2 -0.0 0.4 -0.2 -0.1 -0.1 -0.0 -0.3 -0.1 -0.3 -0.1 0.5 0.0 0.0 0.0 -0.1 -0.1 -0.1 0.1 0.1 -0.0 0.2
Medication for hormone replacement therapy 0.6 0.7 4.6 -0.0 -1.1 -0.6 -0.4 -0.5 -0.7 -1.7 -0.3 -2.1 -0.7 -0.4 -0.8 0.8 0.7 -0.6 0.5 0.6 -0.9 -0.8 -0.9 -0.6 -1.2 -0.9 -0.5 -0.9 -0.3 0.0 -0.6 -0.5 -0.6 -0.7 -0.5 -0.7 -0.1 -1.6 -0.8 -0.2
Vitamin and mineral supplements 0.1 0.2 0.5 0.3 0.6 0.4 0.5 0.5 0.4 0.3 0.2 0.5 0.2 0.4 0.6 -0.4 -0.5 0.4 -0.5 -0.4 0.5 0.3 -0.1 0.2 0.3 0.5 0.4 0.7 0.6 -0.1 -0.0 0.4 0.4 0.4 0.4 0.3 0.4 0.0 0.6 -0.2
Supplements: Zinc 0.6 0.6 1.4 -0.9 -0.5 -1.2 -1.1 -0.8 -0.9 0.2 -0.2 0.5 -0.7 -0.9 -0.5 0.9 0.9 -0.8 1.0 0.9 -0.7 -0.7 -0.6 -0.9 -0.6 -0.8 -0.8 -1.0 -1.1 -0.6 -0.6 -0.8 -0.9 -0.6 -0.8 -0.7 -0.9 -0.3 -1.0 -0.7
Medication: Co-codamol 0.2 0.3 1.3 -0.0 -0.8 -0.4 -0.7 -0.4 -0.7 -1.2 -0.6 -0.9 -0.5 -0.3 -0.7 0.6 0.7 -0.3 0.6 0.5 -0.4 -0.5 -0.4 -0.4 -0.5 -0.7 -0.4 -0.5 -0.7 0.4 -0.2 -0.3 -0.4 -0.4 -0.4 -0.5 -0.2 -0.5 -0.6 0.2
Medication: Metformin 2.7 3.8 6.0 -1.7 -2.4 -2.1 -2.0 -2.1 -1.9 -1.3 -2.0 -2.1 -2.0 -2.1 -1.4 2.0 2.3 -2.0 1.8 1.9 -1.6 -2.1 -2.2 -2.1 -2.0 -2.1 -2.0 -2.1 -2.0 -1.3 -1.8 -2.0 -1.9 -2.0 -2.1 -2.0 -1.8 -1.8 -2.0 -1.2
Diabetes (father) 2.3 2.8 4.0 -1.8 -1.8 -2.0 -1.8 -1.7 -1.7 -1.3 -1.8 -1.7 -1.9 -1.7 -0.2 1.6 1.8 -1.8 1.6 1.7 -1.4 -1.6 -1.8 -1.8 -1.7 -1.6 -1.7 -1.4 -1.3 -1.9 -2.0 -1.6 -1.7 -1.6 -1.7 -1.7 -1.6 -1.6 -1.6 -2.0
Diabetes (mother) 0.3 0.3 1.3 -0.1 0.1 -0.1 0.5 0.4 0.5 -0.7 0.9 0.7 0.6 0.3 0.7 -0.5 -0.7 0.5 -0.5 -0.5 0.3 0.7 0.7 0.4 0.5 0.8 0.5 1.2 0.5 -0.3 0.4 0.4 0.6 0.8 0.4 0.6 0.1 0.8 0.8 0.1
Severe depression (siblings) 0.1 0.1 2.2 0.4 0.1 0.4 0.3 0.2 0.2 -0.2 0.5 -0.2 0.3 0.1 -1.5 -0.0 -0.0 0.1 -0.2 -0.2 0.1 0.0 0.3 0.4 0.3 -0.0 0.1 -0.1 0.2 0.5 0.6 0.2 0.1 -0.1 0.1 0.1 0.2 0.0 0.1 0.5
Pack years adult smoking proportion 0.1 0.1 1.1 -0.3 -0.6 -0.1 -0.5 -0.2 -0.6 -1.0 0.1 -0.8 -0.1 -0.3 0.2 0.3 0.2 -0.2 0.4 0.4 -0.4 -0.3 -0.1 -0.3 -0.4 -0.4 -0.2 -0.3 -0.1 -0.1 -0.0 -0.1 -0.3 -0.2 -0.2 -0.3 -0.3 -0.1 -0.4 -0.2
Impedance of leg (right) 0.2 0.8 1.4 0.9 0.8 0.6 1.1 1.1 1.0 -0.1 0.3 0.5 0.7 1.1 -0.1 -0.7 -0.8 1.1 -1.0 -1.0 1.1 1.0 1.0 0.9 0.7 1.0 1.1 1.2 1.1 0.6 0.9 1.0 1.0 1.0 1.0 1.0 1.0 0.9 1.1 0.9
Leg fat-free mass (left) 0.0 0.2 1.0 -0.3 -0.1 0.6 -0.4 -0.4 -0.4 -1.0 0.7 -0.4 -0.1 -0.3 0.8 0.0 0.1 -0.4 0.3 0.4 -0.3 -0.4 -0.5 -0.4 -0.0 -0.3 -0.4 -0.5 -0.0 0.2 -0.2 -0.3 -0.4 -0.2 -0.3 -0.3 -0.3 0.0 -0.5 0.2
Trunk fat percentage 0.3 1.1 3.9 -1.4 -1.3 -1.0 -1.1 -1.1 -1.2 -2.0 -0.6 -1.3 -0.8 -1.1 0.1 0.9 1.0 -1.0 1.1 1.1 -0.6 -1.0 -1.2 -1.4 -1.0 -0.9 -1.1 -1.1 -0.5 -0.9 -1.1 -0.9 -1.0 -0.6 -1.1 -1.0 -1.2 -0.6 -1.1 -0.7
Hand grip strength (right) 0.5 1.5 3.5 1.9 1.6 1.1 1.5 1.3 1.4 -0.2 1.5 -0.7 0.9 1.4 0.6 -1.2 -0.9 1.3 -1.3 -1.4 1.0 0.9 0.7 1.3 0.7 0.8 1.3 1.1 0.8 1.6 1.2 1.2 1.4 0.9 1.3 1.1 1.8 0.3 1.3 1.5
Townsend deprivation index at recruitment 1.9 2.6 4.4 -2.1 -1.8 -1.6 -2.0 -1.7 -1.9 -0.7 -1.7 -0.5 -1.7 -1.6 -0.1 1.6 1.8 -1.7 1.9 1.8 -1.3 -1.5 -1.5 -1.8 -1.3 -1.4 -1.7 -1.6 -1.1 -1.7 -1.8 -1.7 -1.8 -1.6 -1.7 -1.6 -2.0 -1.0 -1.9 -1.9
Current tobacco smoking 0.2 0.4 1.9 -1.0 -1.4 -0.9 -0.4 -0.7 -0.4 -1.3 -0.5 -0.6 -0.6 -0.8 0.1 0.5 0.4 -0.7 0.3 0.5 -0.1 -0.3 -0.2 -0.7 -0.4 -0.4 -0.6 -0.5 -0.3 -0.5 -0.4 -0.8 -0.5 -0.3 -0.7 -0.5 -1.1 0.1 -0.5 -0.4
Average weekly fortified wine intake 1.1 1.2 5.5 2.0 0.7 1.6 1.2 1.0 0.7 0.2 1.4 -1.4 1.0 1.2 -1.0 -1.0 -0.7 1.1 -0.9 -0.8 0.6 0.7 0.5 0.9 0.4 0.5 1.2 0.5 0.9 2.3 1.2 1.1 1.0 0.9 1.1 0.8 1.7 0.1 0.6 2.2
Maternal smoking around birth 1.9 2.7 5.9 -2.0 -2.2 -2.2 -1.5 -1.6 -1.6 -1.5 -1.1 -1.4 -1.4 -1.7 -0.1 1.9 1.8 -1.6 1.3 1.6 -1.2 -1.4 -1.4 -2.0 -1.8 -1.5 -1.6 -1.3 -2.0 -2.4 -2.1 -1.6 -1.6 -1.4 -1.6 -1.5 -1.9 -1.0 -1.5 -1.9
Fed-up feelings 0.9 1.7 3.4 1.0 1.2 1.0 1.2 1.3 1.4 0.7 1.2 0.9 1.5 1.3 1.0 -1.3 -1.4 1.4 -1.5 -1.3 1.5 1.3 1.5 1.4 1.3 1.4 1.4 1.8 1.8 0.6 1.1 1.5 1.4 1.3 1.3 1.4 1.3 1.1 1.6 0.5
Frequency of unenthusiasm / disinterest in last 2 weeks 0.8 1.1 2.1 1.1 1.1 1.4 0.8 0.9 1.3 0.3 1.1 -0.2 1.3 1.1 -0.1 -1.1 -1.2 1.0 -1.2 -1.1 1.1 0.9 1.1 1.1 1.1 0.9 0.9 0.8 1.1 1.3 1.1 1.0 1.1 1.0 0.9 1.0 1.1 0.9 1.1 1.1
Relative age voice broke 0.1 0.1 1.1 0.4 -0.1 0.1 0.1 0.1 0.1 0.1 0.0 -0.8 0.1 -0.0 -1.1 0.1 0.1 0.2 0.1 -0.1 0.0 -0.1 0.1 0.1 -0.4 -0.1 0.2 0.5 0.2 -0.0 0.0 0.4 0.2 -0.1 0.1 0.1 0.3 -0.4 0.3 -0.2
Taking other prescription medications 0.2 0.3 1.2 0.5 0.3 0.3 0.2 0.4 0.5 -0.1 0.9 1.1 0.3 0.4 0.1 -0.7 -0.3 0.5 -0.5 -0.5 0.3 0.5 0.8 0.8 0.8 0.5 0.4 0.4 0.1 0.6 0.9 0.5 0.5 0.5 0.4 0.5 0.5 0.7 0.5 1.0
Age when periods started (menarche) 0.5 1.1 2.3 0.7 0.9 0.9 1.5 1.1 1.1 1.2 1.0 0.2 1.4 1.2 0.3 -0.8 -1.2 1.1 -1.0 -1.1 1.2 1.1 1.0 0.9 0.9 1.2 1.2 1.3 1.5 0.6 0.6 1.3 1.1 1.1 1.1 1.2 1.0 0.8 1.2 0.2
Bilateral oophorectomy (both ovaries removed) 2.8 3.3 5.8 -1.5 -1.4 -0.9 -1.9 -2.0 -1.9 -1.9 -1.8 -1.6 -2.1 -2.0 -0.8 1.6 1.8 -2.0 2.2 2.0 -2.0 -2.0 -1.7 -1.6 -1.5 -2.1 -2.0 -2.4 -2.1 -1.0 -1.3 -2.0 -2.0 -2.0 -2.0 -2.0 -1.6 -1.6 -2.2 -1.0
Heel bone mineral density (BMD) T-score, automated (left) 1.5 3.4 5.4 -1.1 -1.9 -1.9 -1.8 -1.8 -1.8 -1.6 -1.5 -2.1 -2.0 -1.8 -1.4 2.0 2.3 -1.8 1.9 1.8 -1.4 -2.0 -2.1 -2.2 -2.3 -2.2 -1.8 -2.1 -1.9 -1.2 -1.8 -1.9 -1.8 -1.8 -1.7 -1.9 -1.4 -2.0 -1.9 -1.4
Tinnitus: Yes, but not now, but have in the past 3.0 3.2 5.1 2.2 1.3 1.7 1.5 1.9 2.0 0.1 2.3 -0.1 1.7 1.9 1.9 -1.9 -1.7 1.9 -1.9 -2.0 1.8 1.7 1.8 1.9 1.4 1.5 1.9 2.2 1.6 1.8 1.7 2.0 2.0 1.8 1.9 1.9 2.2 1.2 2.1 1.6
Qualifications: CSEs or equivalent 0.7 0.9 1.7 -1.0 -1.0 -1.1 -1.0 -0.9 -1.0 -0.8 -0.5 -1.1 -1.0 -0.9 -0.7 1.1 0.6 -0.9 0.9 0.9 -1.0 -0.9 -0.9 -1.2 -1.3 -1.0 -0.9 -0.8 -0.5 -1.1 -1.1 -0.9 -1.0 -0.8 -0.9 -0.9 -1.0 -1.0 -1.0 -1.2
Serious illness, injury or assault to yourself 0.1 0.2 1.7 0.8 -0.2 0.5 0.1 0.2 -0.0 -0.0 0.0 -0.8 -0.1 0.2 -0.4 -0.3 0.1 0.1 -0.0 -0.0 -0.2 -0.1 -0.2 0.2 0.1 -0.2 0.1 -0.7 -0.3 1.2 0.5 -0.0 0.0 -0.0 0.1 -0.0 0.5 -0.1 -0.4 1.3
High blood pressure 0.1 0.3 5.3 -0.1 -0.3 1.5 -0.2 -0.1 -0.0 -1.4 1.2 -0.1 -0.1 0.1 2.3 -0.2 -0.5 -0.0 -0.1 0.0 -0.1 0.1 0.1 -0.0 0.1 0.1 -0.1 0.0 -0.1 -0.1 -0.2 -0.1 -0.0 0.1 0.0 0.0 -0.2 0.2 0.0 0.1
Hayfever, allergic rhinitis or eczema 0.1 0.2 1.0 0.1 1.0 0.2 0.5 0.4 0.1 1.0 0.4 0.5 0.4 0.5 -0.0 -0.3 0.0 0.4 -0.3 -0.3 0.5 0.3 0.2 0.3 0.2 0.3 0.4 0.8 0.3 0.0 -0.1 0.6 0.3 0.2 0.4 0.4 0.5 0.4 0.4 0.1
Multivitamins +/- minerals 1.7 2.2 3.2 -1.6 -1.7 -1.7 -1.6 -1.6 -1.7 -1.4 -0.9 -1.1 -1.3 -1.6 -1.0 1.3 1.7 -1.6 1.7 1.7 -1.5 -1.4 -1.3 -1.6 -1.2 -1.5 -1.6 -1.7 -1.6 -1.2 -1.2 -1.5 -1.6 -1.4 -1.6 -1.5 -1.6 -0.7 -1.8 -1.0
Stomach or abdominal pain in last month 1.2 1.5 7.8 1.7 1.0 0.8 1.1 1.2 1.2 2.8 0.8 -0.5 1.4 1.3 -0.1 -0.9 -1.1 1.2 -1.3 -1.2 0.8 0.9 1.0 1.3 0.6 0.9 1.3 0.6 1.2 1.8 1.3 1.2 1.2 1.0 1.2 1.1 1.5 0.1 1.0 1.7
Supplements: Glucosamine 0.3 0.3 1.3 -0.6 -0.5 -0.9 -0.6 -0.6 -0.6 -1.1 -0.4 0.5 -0.6 -0.7 0.5 0.4 0.7 -0.6 0.9 0.6 -0.5 -0.4 -0.4 -0.6 -0.2 -0.4 -0.6 -0.8 -0.6 0.1 -0.1 -0.7 -0.6 -0.2 -0.6 -0.5 -0.8 -0.0 -0.7 0.0
Diverticular disease/diverticulitis (self-reported) 0.1 0.1 1.7 0.4 -0.7 0.4 0.5 0.0 0.1 0.0 -0.1 -1.3 0.3 0.1 -0.7 0.1 -0.4 0.1 -0.2 -0.0 -0.3 -0.1 -0.1 0.0 -0.3 -0.1 0.1 -0.1 0.3 0.5 0.2 0.0 0.1 0.0 0.0 -0.0 0.2 -0.5 0.0 0.4
Medication: Atenolol 0.1 0.2 2.0 -0.3 -0.6 0.6 -0.1 -0.3 -0.1 -1.4 -0.0 0.1 -0.6 -0.2 0.3 -0.1 0.1 -0.3 0.6 0.2 0.2 -0.1 0.1 -0.0 0.5 -0.0 -0.3 -0.5 -0.1 -0.1 -0.1 -0.3 -0.3 -0.2 -0.3 -0.2 -0.4 0.4 -0.2 -0.5
Medication: Levothyroxine sodium 1.6 2.7 4.4 -1.3 -1.7 -2.0 -1.9 -1.7 -1.7 -0.7 -1.3 -1.5 -1.5 -1.6 -1.9 1.2 2.1 -1.7 2.0 1.7 -1.5 -1.8 -1.8 -1.7 -1.5 -1.9 -1.7 -1.7 -1.6 -1.1 -1.5 -1.7 -1.8 -1.7 -1.7 -1.8 -1.2 -1.6 -1.7 -1.5
Sitting height 0.7 4.9 17.5 2.9 2.3 4.2 2.4 2.2 2.4 0.9 2.3 -0.1 2.0 2.4 1.3 -2.1 -2.9 2.2 -2.2 -2.3 1.7 1.8 1.5 2.2 1.7 1.8 2.2 1.9 2.3 2.8 2.1 2.2 2.3 1.9 2.3 2.0 2.7 1.0 2.2 2.4
Chronic bronchitis/emphysema (father) 1.6 1.9 7.1 1.7 1.1 1.3 1.4 1.5 1.3 2.7 1.3 -0.2 1.7 1.6 0.2 -1.1 -1.4 1.6 -1.5 -1.4 0.9 1.2 1.2 1.4 0.7 1.1 1.5 1.4 1.3 1.4 1.2 1.5 1.5 1.1 1.5 1.4 1.7 0.2 1.5 1.2
High blood pressure (mother) 0.1 0.1 1.6 -0.4 -0.4 0.3 -0.4 -0.2 -0.2 -1.3 0.4 0.2 -0.1 -0.3 0.4 0.1 -0.1 -0.1 0.1 0.2 -0.3 -0.1 0.2 -0.0 -0.0 -0.1 -0.1 0.2 -0.3 -0.5 -0.2 -0.2 -0.1 -0.1 -0.2 -0.1 -0.3 0.1 -0.1 -0.4
Body mass index (BMI) 0.5 2.1 3.5 -1.8 -1.7 -1.8 -1.7 -1.6 -1.6 -1.9 -0.7 -1.3 -1.3 -1.6 0.4 1.1 1.5 -1.5 1.6 1.5 -1.0 -1.4 -1.5 -1.8 -1.3 -1.4 -1.6 -1.6 -0.9 -1.2 -1.4 -1.5 -1.5 -1.1 -1.6 -1.5 -1.7 -0.8 -1.6 -1.1
Impedance of leg (left) 0.1 0.5 1.1 0.7 0.5 0.2 1.0 0.9 0.8 -0.2 0.0 0.3 0.4 0.8 -0.4 -0.5 -0.5 0.9 -0.7 -0.8 1.0 0.9 0.7 0.7 0.6 0.8 0.9 0.8 0.8 0.4 0.7 0.8 0.8 0.8 0.8 0.8 0.9 0.7 0.9 0.7
Leg predicted mass (left) 0.0 0.2 0.9 -0.2 -0.1 0.6 -0.4 -0.4 -0.4 -1.0 0.6 -0.4 -0.1 -0.3 0.8 0.0 0.1 -0.4 0.3 0.4 -0.3 -0.4 -0.6 -0.4 -0.1 -0.3 -0.4 -0.5 -0.0 0.2 -0.2 -0.3 -0.4 -0.2 -0.3 -0.4 -0.3 -0.0 -0.5 0.2
Trunk fat mass 0.2 0.9 3.3 -1.3 -1.1 -0.8 -1.0 -1.0 -1.0 -1.8 -0.3 -1.2 -0.7 -1.0 0.3 0.7 0.9 -0.9 1.0 1.0 -0.5 -0.9 -1.1 -1.3 -0.8 -0.8 -1.0 -1.0 -0.4 -0.7 -0.9 -0.8 -0.9 -0.5 -1.0 -0.9 -1.1 -0.4 -1.0 -0.5
Waist circumference 0.4 1.4 4.8 -1.8 -1.6 -1.1 -1.4 -1.3 -1.3 -2.2 -0.6 -0.7 -1.0 -1.3 0.3 0.8 1.1 -1.2 1.3 1.2 -0.6 -1.0 -1.1 -1.4 -0.6 -0.9 -1.3 -1.3 -0.7 -1.2 -1.1 -1.2 -1.2 -0.7 -1.3 -1.1 -1.5 -0.0 -1.3 -0.8
Number of incorrect matches in round 0.3 0.5 2.5 1.4 0.2 1.0 -0.0 0.5 0.5 1.3 0.7 -1.4 0.6 0.6 -0.3 -0.4 -0.7 0.4 -0.0 -0.5 -0.4 0.1 0.2 0.6 -0.2 -0.2 0.4 -0.3 0.4 1.6 0.9 0.5 0.4 0.1 0.6 0.2 0.9 -0.8 0.1 1.0
Past tobacco smoking 0.4 0.6 2.9 1.4 1.3 0.7 0.7 0.9 0.6 1.7 0.7 -0.3 0.9 0.8 -0.7 -0.3 -0.6 0.8 -1.0 -0.7 0.1 0.4 0.5 1.1 0.1 0.4 0.8 0.7 0.7 0.9 0.8 0.9 0.8 0.2 0.8 0.6 1.1 -0.6 0.7 0.9
Alcohol usually taken with meals 0.5 0.7 1.6 -0.7 -0.8 -0.3 -0.6 -0.8 -0.8 -0.4 -1.1 -1.1 -0.8 -0.9 -1.3 0.8 1.1 -0.8 1.1 0.9 -0.9 -0.9 -0.7 -0.6 -0.6 -0.9 -0.8 -1.1 -1.1 -0.4 -0.5 -0.9 -0.9 -1.0 -0.9 -0.9 -0.7 -0.9 -0.9 -0.7
Nervous feelings 0.2 0.4 1.8 0.2 0.6 1.2 0.2 0.3 0.5 1.1 0.6 1.3 0.4 0.3 1.1 -0.9 -0.8 0.3 -0.6 -0.4 0.5 0.5 0.9 0.7 0.8 0.6 0.3 0.9 0.6 -0.4 0.4 0.4 0.4 0.3 0.3 0.5 0.3 0.7 0.7 -0.3
Frequency of tenseness / restlessness in last 2 weeks 0.3 0.4 1.0 0.8 1.0 1.0 0.7 0.5 0.8 0.8 0.4 -0.3 0.7 0.8 0.8 -0.6 -0.7 0.7 -0.9 -0.7 0.6 0.4 0.6 0.8 0.3 0.4 0.6 0.7 0.6 0.6 0.4 0.6 0.7 0.3 0.5 0.6 0.9 0.0 0.8 0.5
Hearing difficulty/problems with background noise 0.8 1.3 5.2 1.8 0.7 2.3 1.2 1.2 1.0 1.8 0.9 -1.0 1.6 1.4 -0.5 -0.8 -1.1 1.3 -1.0 -1.0 0.5 0.7 0.7 1.1 0.4 0.6 1.3 1.2 0.6 1.4 0.8 1.3 1.2 0.8 1.1 1.0 1.7 -0.1 1.1 1.2
Hair/balding pattern: Pattern 2 0.1 0.2 1.4 0.4 0.0 -0.3 -0.0 0.0 -0.2 0.9 -0.2 -1.2 0.0 0.4 -0.8 0.7 0.1 0.1 -0.1 0.1 -0.6 -0.3 -0.4 -0.2 -0.9 -0.3 0.1 0.2 0.3 0.1 -0.5 0.0 -0.0 -0.2 -0.0 -0.1 0.2 -1.0 -0.0 -0.1
Had menopause 4.7 5.8 9.0 2.5 2.1 3.0 2.6 2.5 2.8 2.2 1.9 1.5 2.9 2.6 2.0 -2.4 -2.5 2.6 -2.9 -2.6 2.4 2.3 2.3 2.7 2.3 2.5 2.5 2.5 2.0 2.1 2.0 2.6 2.7 2.2 2.5 2.5 2.6 1.5 2.8 1.9
Had other major operations 0.1 0.1 0.6 0.3 -0.2 0.4 0.4 0.2 0.3 -0.6 0.6 -0.2 0.1 0.1 0.1 -0.4 -0.1 0.2 0.1 -0.2 0.3 0.2 0.0 0.2 0.5 0.2 0.2 -0.2 -0.0 0.8 0.4 0.1 0.2 0.4 0.2 0.2 0.3 0.3 0.0 0.6
Forced vital capacity (FVC) 0.2 0.7 1.5 1.2 0.7 0.9 0.8 0.9 1.0 -0.4 0.9 -0.4 0.6 1.0 -0.3 -0.9 -1.1 0.8 -0.7 -1.0 0.5 0.7 0.8 0.9 0.6 0.5 0.8 0.6 0.5 1.2 1.0 0.6 0.8 0.7 0.9 0.8 1.0 0.5 0.8 1.0
Heel bone mineral density (BMD) T-score, automated (right) 2.5 5.7 7.8 -1.9 -2.4 -2.5 -2.6 -2.4 -2.4 -2.4 -1.9 -2.3 -2.6 -2.4 -1.7 2.4 2.8 -2.5 2.6 2.4 -2.0 -2.5 -2.5 -2.6 -2.5 -2.6 -2.4 -2.7 -2.3 -1.9 -2.4 -2.5 -2.5 -2.4 -2.4 -2.5 -2.1 -2.3 -2.5 -2.2
Ever unenthusiastic/disinterested for a whole week 2.4 2.9 4.9 1.5 1.8 1.7 1.5 1.6 1.6 1.4 2.2 1.8 1.7 1.5 1.0 -2.0 -1.8 1.6 -1.5 -1.6 1.5 1.8 1.9 1.7 1.9 1.6 1.6 1.7 1.5 1.6 2.2 1.6 1.6 1.9 1.6 1.7 1.5 2.1 1.6 1.9
Qualifications: None of the above 0.1 0.3 0.6 -0.6 -0.5 -0.8 -0.6 -0.5 -0.6 -0.1 -0.7 -0.1 -0.7 -0.5 -0.5 0.6 0.5 -0.5 0.6 0.5 -0.6 -0.5 -0.5 -0.5 -0.6 -0.5 -0.5 -0.4 -0.3 -0.6 -0.6 -0.6 -0.6 -0.5 -0.5 -0.5 -0.5 -0.5 -0.5 -0.6
Financial difficulties in last 2 years 2.2 3.0 4.9 -2.2 -1.7 -1.4 -1.9 -1.9 -1.7 -2.1 -1.4 -1.0 -1.9 -1.8 -0.4 1.5 1.5 -1.8 2.0 1.7 -1.6 -1.6 -1.8 -1.9 -1.4 -1.5 -1.8 -1.6 -1.8 -2.2 -2.0 -1.9 -1.7 -1.6 -1.8 -1.7 -1.9 -1.1 -1.6 -2.1
Mouth/teeth dental problems 0.9 1.3 2.7 1.5 1.7 1.1 1.3 1.1 1.0 0.8 1.2 1.5 1.0 1.2 -0.7 -0.8 -1.1 1.2 -1.3 -1.1 0.9 1.1 1.2 1.3 1.0 1.0 1.2 0.8 1.2 1.5 1.4 1.1 1.1 1.0 1.1 1.1 1.1 0.7 1.0 1.5
Heart attack 0.2 0.2 1.4 0.2 -0.6 -0.1 -0.3 -0.2 -0.1 0.7 -0.5 -1.2 -0.2 -0.1 -1.2 0.7 0.5 -0.2 0.3 0.2 -0.2 -0.5 -0.8 -0.4 -0.7 -0.5 -0.2 -0.7 -0.4 0.3 -0.5 -0.3 -0.2 -0.4 -0.2 -0.3 -0.0 -0.7 -0.3 0.3
Allergy 0.1 0.3 0.7 -0.6 -0.8 -0.6 -0.5 -0.5 -0.3 -0.7 -0.8 0.3 -0.5 -0.7 -0.1 0.5 0.2 -0.5 0.4 0.4 -0.7 -0.2 -0.1 -0.4 -0.2 -0.2 -0.5 -0.5 -0.5 -0.8 -0.2 -0.6 -0.5 -0.3 -0.5 -0.4 -0.9 -0.2 -0.4 -0.6
Pain all over the body in last month 2.3 2.5 4.8 2.0 1.1 2.0 1.7 1.5 1.8 1.2 1.8 0.5 1.5 1.7 0.9 -1.9 -1.4 1.6 -1.7 -1.7 2.0 1.3 1.2 1.5 1.4 1.2 1.6 1.3 1.3 2.2 1.5 1.5 1.7 1.5 1.5 1.5 2.0 1.2 1.6 1.7
Diabetes (self-reported) 6.1 9.5 12.2 -3.2 -3.3 -3.0 -3.4 -3.3 -3.4 -2.2 -3.4 -1.8 -3.1 -3.4 -1.3 3.1 3.5 -3.4 3.1 3.3 -2.8 -3.1 -3.1 -3.2 -2.8 -3.1 -3.4 -3.3 -2.9 -2.8 -2.9 -3.3 -3.3 -3.1 -3.3 -3.3 -3.4 -2.5 -3.4 -2.5
Hayfever/allergic rhinitis (self-reported) 0.9 1.2 1.8 -1.1 -0.5 -1.3 -0.9 -1.3 -1.2 0.3 -0.8 0.4 -1.3 -1.2 -1.0 1.1 1.1 -1.2 0.7 1.3 -1.1 -1.3 -1.3 -1.1 -0.9 -1.2 -1.2 -1.2 -1.1 -0.9 -1.0 -1.2 -1.2 -1.2 -1.3 -1.2 -1.0 -1.0 -1.2 -0.8
Medication: Ramipril 0.5 0.7 1.2 -0.9 -0.9 0.5 -1.1 -1.0 -1.0 -0.6 -0.0 -0.7 -0.9 -0.6 0.1 0.7 0.5 -0.9 1.0 1.0 -0.9 -0.9 -1.0 -0.8 -0.5 -0.8 -0.9 -0.7 -0.6 -0.7 -1.0 -0.9 -0.9 -0.8 -1.0 -0.9 -0.9 -0.7 -0.9 -1.0
Medication: Simvastatin 1.2 1.7 4.8 -1.3 -1.7 -0.6 -1.3 -1.4 -1.4 -2.2 -0.9 -1.3 -1.5 -1.3 -0.4 1.2 1.1 -1.4 1.6 1.4 -1.2 -1.3 -1.4 -1.5 -1.0 -1.2 -1.4 -1.7 -1.4 -0.8 -1.2 -1.4 -1.4 -1.1 -1.4 -1.3 -1.5 -0.8 -1.5 -1.0
Fluid intelligence score 0.6 1.2 2.5 -1.5 -0.8 -1.3 -1.2 -1.1 -1.0 -0.6 -1.2 -0.0 -1.0 -1.0 -1.6 0.9 1.5 -1.2 0.8 1.1 -0.4 -1.0 -1.0 -1.0 -0.4 -0.8 -1.1 -0.9 -1.2 -1.5 -1.4 -1.2 -1.1 -1.1 -1.1 -1.0 -1.1 -0.4 -0.9 -1.5
Illnesses of siblings 1.0 1.5 5.8 1.3 1.4 0.1 1.6 1.4 1.3 2.4 0.9 0.5 1.1 1.3 -0.1 -0.8 -1.0 1.3 -1.6 -1.4 1.0 1.2 0.9 1.0 0.6 1.2 1.3 1.6 0.9 0.7 0.8 1.2 1.3 1.3 1.4 1.3 1.3 0.7 1.5 1.2
Neuroticism score 0.1 0.2 0.7 0.6 0.4 0.8 0.4 0.1 0.4 0.1 0.6 -0.6 0.2 0.2 0.8 -0.5 -0.5 0.3 -0.6 -0.2 0.2 0.1 0.2 0.4 0.1 0.1 0.3 0.7 0.7 0.2 0.3 0.4 0.4 0.1 0.1 0.3 0.6 -0.2 0.5 0.1
Weight 0.1 0.4 2.7 -0.8 -0.7 -0.2 -0.8 -0.7 -0.6 -1.7 0.3 -1.0 -0.5 -0.6 0.6 0.3 0.4 -0.6 0.7 0.6 -0.3 -0.6 -0.8 -0.8 -0.3 -0.5 -0.7 -0.8 -0.1 -0.2 -0.5 -0.6 -0.6 -0.3 -0.6 -0.6 -0.6 -0.1 -0.7 -0.2
Impedance of arm (right) 0.0 0.1 0.7 0.0 0.2 0.5 0.0 0.2 0.1 0.3 -0.4 0.1 -0.1 0.2 -0.8 0.3 -0.1 0.2 -0.1 -0.1 0.2 0.1 0.2 0.1 -0.2 0.1 0.2 0.3 0.1 -0.5 -0.4 0.1 0.1 -0.0 0.1 0.1 0.0 -0.3 0.2 -0.4
Arm fat percentage (right) 0.6 2.3 4.1 -2.0 -1.7 -1.6 -1.8 -1.7 -1.6 -1.6 -0.9 -1.4 -1.4 -1.7 -0.1 1.4 1.6 -1.6 1.5 1.6 -1.0 -1.5 -1.7 -1.9 -1.5 -1.4 -1.7 -1.6 -1.0 -1.5 -1.7 -1.6 -1.5 -1.2 -1.7 -1.5 -1.8 -1.0 -1.6 -1.2
Trunk fat-free mass 0.0 0.1 0.6 -0.0 0.2 0.5 -0.1 -0.2 -0.1 -0.6 0.8 -0.1 -0.1 -0.1 0.6 -0.3 -0.1 -0.2 0.3 0.1 -0.1 -0.1 -0.2 -0.0 0.4 -0.1 -0.2 -0.4 -0.0 0.4 0.2 -0.2 -0.2 -0.0 -0.2 -0.2 -0.0 0.3 -0.3 0.4
Hip circumference 0.5 2.2 4.4 -1.6 -1.5 -1.4 -1.7 -1.7 -1.7 -2.1 -0.7 -1.4 -1.4 -1.6 0.2 1.3 1.6 -1.6 1.6 1.6 -1.1 -1.6 -1.7 -1.8 -1.3 -1.5 -1.6 -1.8 -1.1 -1.0 -1.3 -1.5 -1.6 -1.2 -1.6 -1.6 -1.5 -0.9 -1.7 -0.8
Time employed in main current job 0.6 0.7 1.5 -1.0 -1.2 -0.4 -0.7 -0.9 -0.6 -0.4 -1.0 -0.7 -1.0 -0.8 -1.1 1.0 0.5 -0.9 0.8 0.7 -0.5 -0.8 -0.8 -1.0 -0.8 -0.8 -0.9 -1.0 -0.9 -0.9 -1.0 -1.0 -0.8 -0.8 -0.8 -0.8 -1.1 -0.5 -0.7 -0.8
Alcohol intake versus 10 years previously 0.2 0.2 3.0 -0.2 -0.7 0.8 0.2 0.1 0.1 -1.7 0.4 0.2 0.4 -0.1 1.0 -0.6 -0.3 0.1 0.1 -0.1 0.4 0.4 0.4 0.1 0.8 0.4 0.1 0.2 0.4 -0.2 0.3 0.1 0.1 0.4 0.2 0.2 -0.1 1.0 0.1 -0.1
Father’s age at death 0.2 0.3 1.8 1.1 0.4 0.5 0.7 0.4 0.5 0.5 0.5 -1.3 0.2 0.5 -1.3 -0.1 -0.0 0.4 -0.6 -0.5 0.1 -0.0 0.0 0.6 -0.1 -0.0 0.3 -0.1 -0.1 1.0 0.4 0.4 0.4 -0.1 0.4 0.2 0.8 -0.6 0.3 1.1
Worrier / anxious feelings 0.3 0.5 3.6 0.8 0.8 1.2 0.5 0.5 0.6 -0.5 1.0 0.7 0.1 0.4 1.9 -1.0 -0.8 0.5 -0.7 -0.5 0.5 0.5 0.8 0.8 0.7 0.4 0.5 0.5 0.7 0.6 1.0 0.5 0.5 0.5 0.5 0.5 0.7 0.7 0.5 0.9
Frequency of tiredness / lethargy in last 2 weeks 0.0 0.1 0.4 -0.4 -0.1 -0.0 -0.1 -0.1 -0.1 -0.5 0.2 0.4 0.1 0.0 0.3 0.0 -0.1 -0.1 0.2 0.1 0.2 0.1 0.4 -0.0 0.3 0.0 -0.1 0.2 0.0 -0.3 -0.0 -0.0 -0.1 0.1 -0.1 0.0 -0.3 0.6 0.0 -0.4
Falls in the last year 0.1 0.1 1.0 0.4 -0.2 0.3 0.2 0.1 0.0 1.0 0.3 -0.2 0.4 0.4 -1.0 -0.1 -0.0 0.1 -0.2 -0.1 0.0 -0.0 -0.0 0.1 -0.0 -0.1 0.1 -0.3 0.1 0.7 0.1 0.1 0.1 0.0 0.1 0.0 0.3 -0.2 -0.1 0.6
Hair/balding pattern: Pattern 3 0.1 0.2 0.7 -0.5 0.3 -0.8 -0.2 -0.4 -0.3 0.6 -0.5 0.8 -0.6 -0.6 -0.6 0.2 0.5 -0.4 0.4 0.4 -0.2 -0.3 -0.2 -0.4 -0.3 -0.3 -0.4 -0.4 -0.3 -0.5 -0.2 -0.4 -0.4 -0.2 -0.4 -0.3 -0.4 -0.1 -0.3 -0.1
Number of live births 0.1 0.1 0.5 0.1 -0.2 0.1 -0.0 0.0 0.1 -0.6 0.2 0.3 0.0 -0.1 0.7 -0.5 -0.4 -0.0 0.0 -0.1 -0.2 0.3 0.4 0.2 0.3 0.1 0.0 -0.1 0.1 0.4 0.7 0.0 0.1 0.3 0.0 0.2 -0.2 0.5 0.0 0.7
Forced expiratory volume in 1-second (FEV1) 0.3 0.9 1.8 1.2 1.0 1.2 0.8 1.0 1.2 -0.5 1.3 -0.3 0.7 1.1 0.3 -1.0 -1.3 0.9 -0.8 -1.1 0.6 0.9 1.0 0.9 0.6 0.7 1.0 1.0 0.7 1.0 0.9 0.8 1.0 0.9 1.1 0.9 1.0 0.6 1.1 0.6
Pulse rate 0.7 1.2 6.2 -0.4 -1.3 -0.0 -0.7 -0.9 -1.0 0.5 -1.1 -2.5 -0.5 -0.8 -1.8 1.4 0.4 -0.8 0.7 1.0 -1.7 -1.2 -1.3 -1.0 -1.7 -1.1 -0.8 -1.1 -0.8 -0.4 -1.0 -0.9 -0.9 -1.1 -0.9 -1.0 -0.8 -2.0 -1.1 -0.5
Happiness 0.3 0.4 2.6 0.2 0.1 0.1 -0.4 -0.2 -0.2 1.6 -0.1 -1.5 -0.4 -0.0 -0.7 0.7 0.1 -0.2 -0.2 0.3 -0.7 -0.6 -0.5 -0.3 -1.1 -0.7 -0.2 -0.4 -0.4 -0.2 -0.7 -0.4 -0.2 -0.6 -0.3 -0.4 0.0 -1.4 -0.2 -0.3
Noisy workplace 1.6 1.9 3.6 1.5 1.2 1.3 1.2 1.4 1.7 -0.0 1.4 0.9 1.3 1.5 1.4 -1.9 -1.4 1.5 -1.0 -1.6 1.3 1.4 1.4 1.4 1.4 1.2 1.4 1.4 0.9 1.5 1.6 1.5 1.6 1.4 1.4 1.5 1.5 1.2 1.6 1.1
Qualifications: A levels/AS levels or equivalent 0.3 0.8 3.6 1.5 0.9 1.3 0.6 0.8 0.8 1.8 0.8 0.2 0.9 0.9 -0.7 -0.8 -0.7 0.7 -0.7 -0.8 0.7 0.4 0.1 0.7 0.6 0.5 0.8 0.3 0.5 1.9 0.9 0.7 0.8 0.7 0.8 0.6 1.2 0.2 0.5 1.6
Serious illness, injury or assault of a close relative in last 2 years 0.6 0.7 1.7 0.7 1.3 0.7 0.7 0.8 0.7 0.8 1.1 0.8 0.8 0.6 0.9 -1.0 -0.7 0.7 -0.9 -0.7 0.8 0.8 0.8 0.9 1.0 0.8 0.7 0.5 0.7 0.7 1.0 0.7 0.7 0.7 0.7 0.7 0.8 0.8 0.6 1.2
Mouth/teeth dental problems: Dentures 1.3 2.1 3.2 -1.4 -1.6 -1.0 -1.5 -1.6 -1.6 -0.6 -1.7 -1.8 -1.2 -1.4 -0.4 1.3 1.0 -1.5 1.6 1.6 -1.8 -1.5 -1.5 -1.7 -1.7 -1.6 -1.5 -1.4 -1.4 -1.1 -1.5 -1.3 -1.6 -1.4 -1.5 -1.5 -1.6 -1.4 -1.6 -1.5
Asthma 1.4 2.7 6.6 1.5 1.5 1.5 1.5 1.6 1.5 0.4 2.3 0.8 1.6 1.5 2.6 -2.2 -1.5 1.6 -1.4 -1.6 2.0 1.6 1.6 1.4 1.7 1.4 1.6 1.4 1.9 1.6 1.8 1.6 1.6 1.8 1.6 1.6 1.8 2.0 1.4 1.7
Medication: Ibuprofen (e.g. Nurofen) 0.1 0.1 0.8 -0.1 -0.1 -0.0 0.1 0.2 0.3 -0.5 0.1 0.9 0.1 -0.0 0.4 -0.1 -0.3 0.2 -0.6 -0.2 0.4 0.4 0.6 0.5 0.4 0.5 0.2 0.5 0.4 -0.4 0.2 0.1 0.3 0.2 0.2 0.3 -0.1 0.3 0.4 0.1
Medication: Cholesterol lowering 1.5 2.4 3.5 -1.1 -1.5 -0.9 -1.7 -1.6 -1.7 -1.2 -1.5 -1.4 -1.4 -1.4 -1.6 1.7 1.6 -1.5 1.8 1.6 -1.9 -1.6 -1.9 -1.6 -1.6 -1.6 -1.6 -1.8 -1.8 -0.8 -1.4 -1.4 -1.6 -1.5 -1.6 -1.6 -1.5 -1.6 -1.8 -0.8
Depression (self-reported) 0.4 0.5 1.1 -0.5 -0.6 -0.5 -0.7 -0.8 -0.5 0.0 -0.7 -1.0 -0.6 -0.9 -1.0 0.6 0.5 -0.8 0.5 0.6 -0.6 -0.9 -0.7 -0.7 -0.7 -0.9 -0.8 -1.0 -0.6 -0.8 -0.5 -0.8 -0.7 -0.8 -0.8 -0.8 -0.5 -0.8 -0.7 -0.5
Medication: Lansoprazole 0.1 0.1 0.6 -0.3 -0.1 0.1 0.2 0.1 -0.0 -0.8 0.1 -0.7 0.2 0.3 0.5 0.2 0.1 0.1 -0.4 -0.0 0.4 -0.0 -0.1 -0.1 -0.0 0.2 0.1 0.2 0.2 -0.3 -0.5 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.1 -0.2
Prospective memory result 0.5 0.6 2.3 -0.0 0.0 0.8 0.7 0.6 0.7 -0.4 0.8 1.0 0.7 0.4 1.0 -0.9 -1.2 0.7 -0.6 -0.6 0.7 1.0 1.1 0.7 1.1 1.1 0.7 1.0 0.8 -0.3 0.7 0.8 0.7 1.0 0.6 0.9 0.3 1.5 0.8 0.2
Lung cancer (father) 0.3 0.3 1.0 -0.8 -0.2 -0.8 -0.6 -0.6 -0.4 0.9 -0.3 0.1 -0.5 -0.7 0.3 0.5 0.3 -0.5 0.1 0.5 -0.4 -0.6 -0.8 -0.8 -0.8 -0.5 -0.6 -0.5 -0.6 -1.0 -0.7 -0.5 -0.5 -0.4 -0.7 -0.5 -0.7 -0.5 -0.4 -0.4
Illnesses of mother 1.1 1.3 10.8 1.3 1.6 0.9 1.2 1.0 1.1 3.3 0.7 0.4 1.0 1.2 0.3 -0.8 -1.1 1.0 -1.4 -1.1 0.9 0.8 0.5 1.0 0.7 0.9 1.0 0.7 1.3 1.5 0.8 1.0 1.0 0.9 1.1 0.9 1.2 0.3 0.9 1.4
Forced expiratory volume in 1-second (FEV1), Best measure 0.5 1.5 2.8 1.3 1.3 1.2 1.2 1.4 1.5 -0.5 1.3 0.4 0.9 1.4 1.0 -1.4 -1.7 1.2 -1.2 -1.4 0.9 1.3 1.3 1.2 1.0 1.1 1.3 1.5 1.0 1.1 1.3 1.1 1.3 1.3 1.4 1.3 1.3 1.1 1.5 0.9
Pulse wave Arterial Stiffness index 1.1 1.3 10.8 -0.7 -2.3 -0.3 -1.0 -0.9 -0.8 -3.3 -0.7 -1.8 -1.0 -1.0 -0.7 0.8 0.5 -1.0 1.2 0.9 -1.2 -0.9 -1.0 -1.1 -1.1 -1.0 -1.0 -1.0 -0.6 -0.6 -0.8 -1.0 -1.0 -0.8 -0.9 -1.0 -1.0 -0.9 -1.0 -0.9
Impedance of arm (left) 0.1 0.4 1.8 0.7 0.7 1.3 0.7 0.7 0.5 0.3 0.1 0.4 0.6 0.7 -0.4 -0.3 -0.7 0.7 -0.7 -0.6 0.6 0.6 0.7 0.6 0.3 0.6 0.7 0.9 0.6 0.3 0.3 0.7 0.7 0.5 0.7 0.7 0.6 0.3 0.7 0.4
Arm fat mass (right) 0.4 1.5 2.9 -1.6 -1.4 -1.2 -1.5 -1.4 -1.4 -1.7 -0.5 -1.1 -1.1 -1.4 0.1 1.0 1.2 -1.3 1.4 1.4 -0.8 -1.3 -1.4 -1.6 -1.1 -1.2 -1.4 -1.4 -0.7 -1.0 -1.2 -1.3 -1.3 -0.9 -1.4 -1.3 -1.5 -0.6 -1.4 -0.9
Trunk predicted mass 0.0 0.1 0.6 0.0 0.2 0.6 -0.1 -0.2 -0.1 -0.5 0.8 -0.1 -0.1 -0.1 0.5 -0.3 -0.1 -0.2 0.3 0.1 -0.1 -0.1 -0.2 -0.0 0.4 -0.1 -0.2 -0.4 0.0 0.5 0.3 -0.2 -0.2 -0.0 -0.1 -0.1 0.0 0.4 -0.3 0.4
Standing height 0.3 2.9 10.6 2.2 1.9 3.3 1.9 1.7 1.8 0.0 1.9 0.2 1.6 1.9 0.5 -1.6 -2.0 1.7 -1.6 -1.7 1.3 1.4 1.3 1.8 1.7 1.5 1.7 1.3 1.4 2.1 1.7 1.7 1.7 1.4 1.8 1.6 2.1 1.1 1.6 2.0
Length of working week for main job 0.6 0.7 2.2 -0.6 -1.2 -0.6 -1.1 -0.8 -0.6 -1.0 -0.5 -1.5 -0.9 -0.8 -0.2 0.8 0.7 -0.8 0.7 0.7 -0.3 -0.9 -0.9 -1.0 -1.1 -0.9 -0.8 -0.8 -0.3 -0.7 -0.9 -0.8 -0.7 -0.8 -0.8 -0.8 -0.6 -0.9 -0.7 -0.9
Exposure to tobacco smoke at home 1.5 1.7 4.4 -2.1 -0.9 -2.1 -1.5 -1.4 -1.5 -2.0 -1.0 1.6 -1.8 -1.5 1.0 0.9 1.2 -1.4 1.1 1.4 -0.6 -0.8 -0.5 -1.3 -0.4 -0.9 -1.4 -0.9 -0.9 -1.7 -0.8 -1.5 -1.4 -0.8 -1.4 -1.1 -1.9 0.7 -1.3 -1.1
Breastfed as a baby 0.2 0.3 0.6 -0.3 -0.4 -0.4 -0.8 -0.6 -0.6 -0.5 -0.5 0.1 -0.4 -0.7 0.1 0.5 0.7 -0.7 0.4 0.6 -0.4 -0.7 -0.5 -0.5 -0.5 -0.7 -0.7 -0.6 -0.6 -0.1 -0.3 -0.5 -0.6 -0.7 -0.7 -0.6 -0.5 -0.5 -0.6 -0.2
Tense / ‘highly strung’ 0.2 0.3 2.5 0.4 -0.7 0.1 -0.1 -0.4 -0.1 0.3 -0.2 -1.6 -0.3 -0.3 -0.7 0.4 0.1 -0.3 0.3 0.2 -0.8 -0.7 -0.4 -0.1 -0.8 -0.8 -0.3 -0.6 -0.1 0.3 -0.0 -0.2 -0.2 -0.6 -0.4 -0.4 0.1 -1.2 -0.3 0.1
Seen doctor (GP) for nerves, anxiety, tension or depression 3.5 5.3 11.6 1.7 2.1 2.0 2.5 2.3 2.4 0.6 2.3 1.7 2.4 2.0 3.4 -2.8 -2.3 2.3 -2.2 -2.4 2.4 2.4 2.5 2.4 2.6 2.5 2.3 2.5 2.2 1.4 2.5 2.4 2.4 2.4 2.3 2.4 2.2 2.5 2.6 1.7
Hair/balding pattern: Pattern 4 0.6 1.4 5.1 -0.8 -1.3 -0.6 -1.0 -1.1 -1.1 -0.5 -0.9 -2.2 -0.9 -1.1 -0.1 1.3 1.2 -1.0 1.0 1.1 -1.1 -1.2 -1.2 -1.2 -1.6 -1.3 -1.0 -0.9 -1.4 -1.2 -1.5 -1.1 -1.1 -1.3 -1.0 -1.2 -0.8 -1.7 -1.1 -1.5
Birth weight of first child 0.9 1.6 2.8 1.3 1.2 1.3 1.4 1.4 1.2 1.5 0.9 0.8 1.5 1.7 -0.6 -0.9 -1.4 1.4 -1.2 -1.3 1.1 1.3 1.5 1.6 1.3 1.4 1.4 1.4 1.1 1.3 1.2 1.4 1.4 1.1 1.4 1.4 1.2 1.0 1.4 1.1
Peak expiratory flow (PEF) 0.1 0.2 6.2 -0.2 -0.1 -0.1 -0.3 0.1 0.2 -2.5 0.6 0.2 -0.2 0.0 0.4 -0.2 -0.3 -0.0 0.2 -0.1 0.3 0.3 0.5 -0.1 0.1 0.1 0.0 0.3 0.2 -0.2 0.1 -0.0 0.0 0.2 0.1 0.1 -0.2 0.6 0.2 -0.5
Pulse wave reflection index 0.1 0.1 1.4 0.3 -0.5 0.2 0.1 0.1 0.3 -1.2 0.4 0.0 0.0 0.0 0.1 -0.5 -0.1 0.1 -0.1 -0.3 0.4 0.2 0.0 0.1 0.4 0.2 0.1 -0.1 0.4 0.4 0.4 0.1 0.1 0.2 0.2 0.1 0.3 0.4 0.1 0.3
Ever highly irritable/argumentative for 2 days 0.3 0.3 1.2 -0.9 -0.6 -0.7 -0.3 -0.5 -0.5 -1.1 -0.1 -0.0 -0.7 -0.8 0.5 0.3 0.6 -0.5 0.8 0.5 -0.1 -0.3 -0.3 -0.6 -0.2 -0.4 -0.5 -0.7 -0.6 -0.9 -0.3 -0.5 -0.5 -0.3 -0.6 -0.4 -0.7 0.1 -0.5 -0.6
Loud music exposure frequency 0.9 1.0 2.7 1.4 1.1 0.7 0.9 1.0 1.1 0.9 0.9 -0.4 0.8 0.9 1.6 -1.1 -0.5 0.9 -0.8 -1.0 1.3 0.6 0.6 0.9 0.7 0.5 0.9 0.6 1.0 1.4 1.1 1.0 1.0 0.7 0.9 0.8 1.6 0.5 0.9 1.3
Qualifications: O levels/GCSEs or equivalent 0.5 0.9 3.0 1.6 1.1 1.1 0.7 0.9 1.0 0.4 1.0 -0.6 0.7 1.0 0.5 -0.8 -0.5 0.9 -0.9 -1.0 1.1 0.6 0.3 0.8 0.5 0.5 0.9 0.6 0.7 1.7 0.8 1.0 0.9 0.7 1.0 0.8 1.5 0.2 0.8 1.5
Mouth/teeth dental problems: Bleeding gums 0.4 0.5 1.9 -1.1 -0.7 -0.7 -0.8 -0.6 -0.3 -1.1 -0.3 -0.7 -1.2 -0.6 1.2 0.2 0.6 -0.7 0.7 0.4 -0.1 -0.5 -0.8 -0.8 -0.2 -0.4 -0.7 -0.3 -0.7 -1.3 -1.1 -0.8 -0.6 -0.5 -0.6 -0.6 -0.7 -0.1 -0.3 -1.4
Blood clot in the leg (DVT) 0.4 0.5 2.9 0.3 -0.4 -0.2 -0.6 -0.5 -0.5 0.3 -0.5 -1.7 -0.3 -0.2 -1.7 0.7 0.4 -0.5 0.5 0.5 -0.8 -0.8 -0.9 -0.6 -1.1 -0.9 -0.5 -0.8 -0.2 0.5 -0.6 -0.5 -0.5 -0.7 -0.5 -0.7 -0.1 -1.4 -0.6 0.1
Medication: Paracetamol 0.3 0.4 1.1 1.0 0.6 0.4 0.4 0.6 0.5 -0.8 1.0 0.3 0.6 0.6 0.8 -0.5 -0.4 0.6 -1.0 -0.6 0.7 0.4 0.4 0.6 0.2 0.3 0.6 0.8 0.8 0.8 0.6 0.7 0.6 0.5 0.6 0.5 1.0 0.1 0.7 1.0
Headache pain in last month 3.2 5.5 8.4 1.9 2.3 2.2 1.9 2.3 2.4 1.0 2.3 2.6 2.3 2.2 2.0 -2.3 -2.7 2.4 -2.4 -2.4 2.0 2.6 2.9 2.5 2.4 2.5 2.4 2.8 2.5 1.6 2.5 2.5 2.4 2.5 2.3 2.5 2.0 2.5 2.6 2.1
Medication for cholesterol, blood pressure or diabetes 0.1 0.2 0.7 0.2 0.8 -0.5 0.4 0.4 0.5 0.8 0.0 0.6 0.1 0.3 -0.2 -0.4 -0.1 0.3 -0.6 -0.4 0.8 0.3 0.4 0.4 0.4 0.3 0.4 0.5 0.6 -0.2 0.1 0.2 0.4 0.2 0.4 0.4 0.5 0.3 0.5 -0.3
Glaucoma (self-reported) 1.2 1.4 3.3 0.9 1.2 1.6 1.3 0.9 1.1 0.7 1.1 1.7 1.2 0.9 1.8 -1.2 -1.1 1.0 -1.4 -1.1 1.5 1.1 1.1 1.1 1.4 1.1 1.0 1.1 1.1 1.1 1.3 1.1 1.1 1.1 1.0 1.1 1.0 1.4 1.1 1.4
Gout (self-reported) 1.1 1.5 2.1 -1.1 -1.4 -1.2 -1.3 -1.2 -1.2 -0.3 -1.4 -0.6 -1.0 -1.4 -0.7 1.4 1.4 -1.3 1.2 1.2 -1.0 -1.2 -1.3 -1.3 -1.2 -1.1 -1.3 -1.1 -1.4 -1.3 -1.4 -1.2 -1.2 -1.3 -1.2 -1.2 -1.2 -1.1 -1.2 -1.1
Hypothyroidism/myxoedema (self-reported) 3.3 6.5 10.4 -2.3 -2.6 -3.2 -2.9 -2.7 -2.6 -1.4 -2.3 -1.7 -2.5 -2.6 -2.5 2.2 3.2 -2.7 2.9 2.7 -2.2 -2.7 -2.7 -2.7 -2.4 -2.8 -2.7 -2.8 -2.5 -1.8 -2.4 -2.7 -2.7 -2.6 -2.7 -2.7 -2.2 -2.2 -2.7 -2.1
Medication: Amlodipine 0.2 0.2 1.9 -0.2 0.2 1.0 0.2 0.1 0.1 -1.4 1.0 0.4 0.1 0.4 1.1 -0.4 -0.9 0.2 -0.2 -0.1 0.1 0.3 0.3 0.1 0.4 0.4 0.1 0.6 0.4 -0.2 -0.1 0.3 0.2 0.4 0.1 0.2 -0.2 0.6 0.3 -0.5
Medication: Ventolin 100micrograms inhaler 0.3 0.4 2.1 0.2 0.7 0.3 0.4 0.5 0.5 0.7 1.0 1.4 0.8 0.5 1.2 -0.8 -0.6 0.6 -0.4 -0.5 0.5 0.7 0.8 0.6 0.8 0.7 0.6 0.7 0.5 0.2 0.7 0.6 0.6 0.6 0.5 0.6 0.3 1.0 0.6 0.2
Birth weight 1.9 4.2 6.2 1.6 2.2 2.1 2.2 2.1 2.0 -0.4 1.7 1.6 1.9 2.2 2.0 -2.4 -2.3 2.2 -2.0 -2.1 2.0 2.1 1.8 2.0 2.3 2.3 2.2 2.5 2.1 1.4 1.8 2.1 2.1 2.2 2.2 2.1 2.1 2.2 2.3 1.3
Chronic bronchitis/emphysema (mother) 0.3 0.3 1.4 0.2 -0.2 -0.1 0.1 -0.3 -0.7 0.0 -0.6 -1.2 -0.3 -0.1 -0.2 0.9 0.8 -0.3 0.4 0.5 -0.6 -0.7 -1.0 -0.6 -1.0 -0.7 -0.3 -0.5 -0.5 0.3 -0.7 -0.3 -0.5 -0.5 -0.3 -0.6 0.0 -1.1 -0.7 0.2
High blood pressure (siblings) 1.5 2.2 5.5 -1.8 -1.1 -0.5 -2.1 -1.8 -1.5 -2.4 -1.1 -0.2 -1.6 -1.7 0.5 1.3 1.1 -1.7 1.7 1.6 -1.6 -1.5 -1.2 -1.4 -1.0 -1.4 -1.7 -1.9 -1.6 -1.2 -1.3 -1.6 -1.6 -1.5 -1.7 -1.5 -1.9 -0.9 -1.7 -1.2
Forced vital capacity (FVC), Best measure 0.3 0.9 1.7 1.3 1.0 1.0 1.0 1.1 1.1 -0.7 0.9 0.1 0.6 1.1 0.1 -1.1 -1.3 0.9 -0.9 -1.1 0.5 0.9 0.9 1.1 0.8 0.7 1.0 0.8 0.6 1.2 1.2 0.8 1.0 0.9 1.1 0.9 1.2 0.7 1.0 1.2
Body fat percentage 0.2 0.9 3.0 -1.4 -1.2 -1.1 -1.1 -1.0 -1.0 -1.7 -0.5 -1.1 -0.7 -0.9 0.3 0.8 1.0 -0.9 1.0 1.0 -0.4 -0.8 -1.0 -1.3 -0.9 -0.7 -1.0 -0.9 -0.3 -0.9 -1.0 -0.8 -0.9 -0.4 -1.0 -0.9 -1.2 -0.3 -0.9 -0.6
Leg fat percentage (right) 0.1 0.5 2.7 -1.1 -1.0 -1.2 -0.8 -0.7 -0.6 -1.7 -0.1 -0.8 -0.7 -0.7 1.0 0.3 0.7 -0.6 0.6 0.6 0.0 -0.4 -0.6 -0.9 -0.5 -0.4 -0.6 -0.5 0.1 -0.6 -0.5 -0.6 -0.5 -0.1 -0.6 -0.5 -0.8 0.2 -0.6 -0.2
Arm fat-free mass (right) 0.0 0.1 0.9 0.1 0.1 0.7 0.1 -0.1 -0.1 -0.9 0.9 -0.2 0.2 0.0 0.6 -0.3 -0.3 -0.0 0.1 0.0 -0.1 0.0 -0.1 0.0 0.4 0.0 -0.1 -0.3 0.2 0.6 0.4 0.1 -0.0 0.2 -0.0 -0.0 0.1 0.5 -0.2 0.7
Exposure to tobacco smoke outside home 0.5 0.7 2.1 -0.6 -0.8 -1.4 -1.0 -0.7 -0.8 -1.4 -0.6 -1.4 -1.0 -0.6 0.5 1.0 0.9 -0.7 0.7 0.7 -0.7 -0.8 -0.7 -0.9 -1.2 -0.9 -0.7 -0.5 -0.6 -0.8 -1.0 -0.8 -0.7 -0.7 -0.7 -0.7 -0.7 -0.9 -0.7 -0.9
Comparative body size at age 10 0.3 0.9 2.5 0.9 0.6 0.6 0.8 0.9 0.7 -1.6 1.2 0.1 0.7 0.9 1.2 -1.1 -1.0 0.9 -0.9 -0.9 0.7 0.9 0.9 0.9 0.9 0.8 0.8 0.6 1.3 1.3 1.3 0.8 0.9 1.0 1.0 0.9 0.8 1.0 0.7 1.3
Number of full brothers 0.5 0.6 1.5 1.1 0.8 0.6 0.6 0.8 0.7 1.2 0.7 -0.0 0.8 0.6 -0.1 -1.0 -0.7 0.7 -0.5 -0.8 0.6 0.6 0.7 0.8 0.5 0.4 0.7 0.6 0.9 1.2 1.2 0.8 0.7 0.6 0.8 0.7 1.0 0.4 0.6 0.9
Worry too long after embarrassment 0.1 0.1 0.5 0.6 0.6 0.7 0.4 0.2 0.2 -0.3 0.7 -0.0 -0.1 0.2 0.1 -0.4 -0.5 0.2 -0.6 -0.1 -0.0 0.1 0.1 0.2 -0.1 0.1 0.2 0.5 0.6 0.2 0.3 0.3 0.2 0.2 0.1 0.2 0.5 -0.1 0.3 0.5
Seen a psychiatrist for nerves, anxiety, tension or depression 4.1 5.3 8.0 1.9 1.6 1.9 2.3 2.2 2.5 0.3 2.6 1.8 2.1 2.1 2.8 -2.8 -2.4 2.2 -2.4 -2.4 2.7 2.4 2.5 2.3 2.6 2.3 2.2 2.3 2.6 1.8 2.5 2.2 2.4 2.5 2.2 2.4 2.2 2.8 2.5 2.0
Wheeze or whistling in the chest in last year 0.2 0.4 1.3 0.5 0.5 0.5 0.4 0.4 0.6 0.1 1.1 0.7 0.5 0.3 1.0 -0.7 -0.7 0.5 -0.6 -0.5 0.9 0.5 0.5 0.3 0.6 0.4 0.5 0.3 0.9 0.8 1.0 0.6 0.6 0.9 0.4 0.6 0.5 1.1 0.5 1.1
Number of children fathered 0.5 0.5 1.3 1.1 0.4 0.7 0.9 0.8 1.0 0.6 0.5 -0.7 0.7 0.7 -0.4 -0.7 -0.4 0.7 -0.6 -0.9 1.0 0.5 0.5 0.7 0.3 0.4 0.7 0.4 0.7 1.1 0.6 0.6 0.8 0.5 0.8 0.7 1.0 0.0 0.8 0.8
Reason for reducing amount of alcohol drunk: Health precaution 1.3 1.5 3.2 1.8 1.4 1.7 1.3 1.4 1.1 1.7 1.0 0.6 1.4 1.5 0.1 -1.0 -1.4 1.3 -0.9 -1.2 0.4 1.2 1.2 1.5 0.9 1.1 1.3 1.1 1.1 1.7 1.4 1.3 1.2 1.0 1.3 1.2 1.4 0.2 1.1 1.2
Age at first live birth 0.5 0.9 2.1 0.8 1.2 0.8 0.7 1.1 1.0 0.0 1.2 1.5 1.0 1.0 -0.0 -1.0 -0.9 0.9 -0.8 -1.0 0.9 1.2 1.3 1.0 1.1 1.0 1.0 1.3 0.8 0.4 0.9 1.0 1.0 1.0 1.1 1.0 0.9 1.1 1.1 0.2
Pulse wave peak to peak time 1.6 1.9 11.4 0.9 2.6 0.7 1.3 1.2 1.1 3.4 1.1 2.0 1.3 1.3 0.7 -1.1 -0.9 1.3 -1.4 -1.2 1.4 1.2 1.2 1.4 1.4 1.3 1.3 1.2 0.9 0.9 1.1 1.3 1.3 1.1 1.2 1.3 1.2 1.2 1.2 1.2
Health satisfaction 1.3 1.7 2.9 -1.3 -1.4 -0.9 -1.4 -1.4 -1.3 -0.1 -0.9 -1.2 -1.1 -1.3 -0.9 1.6 1.2 -1.2 1.7 1.3 -1.2 -1.3 -1.2 -1.4 -1.3 -1.4 -1.3 -1.6 -1.1 -1.2 -1.4 -1.4 -1.3 -1.4 -1.4 -1.3 -1.4 -1.2 -1.4 -1.6
Shortness of breath walking on level ground 1.1 1.3 2.9 -0.5 -0.8 -0.8 -1.1 -1.1 -1.2 0.4 -1.3 -1.5 -0.8 -1.0 -1.6 1.4 1.3 -1.0 0.9 1.2 -1.2 -1.4 -1.6 -1.2 -1.6 -1.4 -1.0 -1.2 -1.4 -0.4 -1.2 -0.9 -1.1 -1.2 -1.1 -1.2 -0.7 -1.7 -1.2 -0.4
Qualifications: College or University degree 0.4 1.3 2.3 1.5 1.1 1.2 1.3 1.1 1.3 0.8 1.1 0.3 1.3 1.1 0.5 -1.2 -0.9 1.2 -1.4 -1.2 1.1 0.9 0.8 1.2 1.0 1.0 1.2 1.0 1.1 1.3 1.2 1.2 1.2 1.0 1.1 1.1 1.4 0.5 1.2 1.4
Eye problems/disorders: None of the above 0.6 0.7 1.8 -0.3 -0.4 -1.0 -0.9 -0.7 -0.8 -0.3 -0.7 -0.7 -0.8 -0.6 -0.9 0.5 1.0 -0.8 1.0 0.7 -1.3 -1.0 -1.0 -0.7 -0.9 -1.0 -0.8 -1.1 -1.3 -0.1 -0.6 -0.8 -0.8 -1.0 -0.7 -0.9 -0.5 -1.3 -0.9 -0.5
Mouth/teeth dental problems: Loose teeth 0.8 0.9 1.6 -1.2 -0.8 -1.0 -1.0 -1.0 -1.0 -0.2 -0.9 -0.4 -1.1 -1.1 -0.1 1.0 0.7 -1.0 0.6 1.0 -1.1 -0.9 -1.0 -1.0 -1.0 -0.9 -1.0 -0.9 -1.0 -1.3 -1.1 -1.1 -1.0 -0.9 -1.0 -1.0 -1.1 -0.9 -0.9 -0.9
Emphysema/chronic bronchitis 0.8 0.9 2.2 0.8 0.9 1.1 1.1 0.8 0.7 0.6 0.9 1.2 0.8 0.9 0.2 -1.1 -1.1 0.9 -0.7 -0.8 0.6 1.0 1.2 1.2 1.4 1.0 0.9 0.5 0.5 1.5 1.4 0.9 0.9 0.9 0.8 0.9 0.8 1.1 0.6 1.3
Medication for pain relief, constipation, heartburn 0.3 0.5 8.0 0.4 1.0 0.6 0.7 0.6 0.5 2.8 0.3 0.7 0.7 0.7 -0.5 -0.5 -0.7 0.6 -0.2 -0.6 0.3 0.6 0.6 0.5 0.6 0.6 0.6 0.7 0.5 0.3 0.4 0.5 0.5 0.6 0.6 0.6 0.5 0.5 0.6 -0.0
Neck or shoulder pain in last month 1.3 1.8 4.8 0.6 1.9 1.0 1.3 1.3 1.4 0.9 0.9 2.2 1.0 1.5 1.4 -1.1 -1.5 1.4 -1.5 -1.4 1.5 1.6 1.5 1.3 1.4 1.7 1.3 1.6 1.3 0.5 0.8 1.3 1.4 1.5 1.3 1.5 0.8 1.5 1.5 0.7
Medication: Blood pressure 0.1 0.1 1.3 -0.0 -0.4 0.7 -0.1 -0.1 -0.0 -1.0 0.7 -0.0 0.1 -0.1 1.1 -0.1 -0.3 -0.0 0.0 0.0 -0.1 0.1 0.2 -0.0 0.1 0.1 -0.1 -0.1 0.0 0.1 0.2 0.0 0.0 0.2 -0.0 0.0 -0.3 0.2 -0.0 0.3
Angina (self-reported) 0.0 0.0 0.3 0.3 -0.1 0.0 -0.2 -0.1 0.2 0.0 0.1 -0.5 -0.1 0.1 -0.4 0.1 0.2 -0.0 0.1 -0.0 0.4 -0.2 -0.1 -0.1 -0.0 -0.3 -0.1 -0.3 -0.0 0.5 0.1 0.1 0.1 -0.1 -0.1 -0.0 0.2 0.1 0.0 0.3
Migraine (self-reported) 0.1 0.1 2.4 -0.4 -0.2 0.5 0.2 -0.0 -0.2 -0.0 -0.1 1.6 0.2 -0.1 -0.5 -0.1 -0.4 0.0 0.0 0.1 0.0 0.2 0.5 0.1 0.3 0.2 0.0 -0.1 0.6 -0.3 0.4 0.1 -0.1 0.2 -0.0 0.1 -0.3 0.6 -0.1 0.3
Medication: Ibuprofen 1.0 1.2 2.3 0.6 0.5 1.0 1.0 1.0 1.2 -0.3 1.0 1.3 1.0 0.9 0.8 -1.0 -1.3 1.1 -1.4 -1.1 1.1 1.3 1.5 1.3 1.2 1.4 1.1 1.4 1.2 0.2 1.1 0.9 1.2 1.1 1.0 1.2 0.6 1.2 1.4 0.7
Medication: Allopurinol 0.6 0.9 1.9 -0.9 -1.3 -1.1 -0.9 -0.9 -0.8 -1.2 -1.4 -0.2 -0.8 -1.1 0.1 1.1 1.2 -0.9 1.0 0.9 -0.6 -0.7 -0.9 -1.0 -0.7 -0.7 -0.9 -0.8 -1.2 -1.1 -1.0 -0.9 -0.9 -0.8 -0.9 -0.9 -1.0 -0.5 -0.9 -0.8
Medication: Omeprazole 0.2 0.2 0.9 0.7 0.8 0.1 0.5 0.5 0.5 0.3 0.7 0.2 0.3 0.5 -0.1 -0.4 -0.3 0.6 -0.6 -0.5 0.3 0.4 0.5 0.4 0.2 0.3 0.5 0.2 -0.1 0.8 0.6 0.5 0.5 0.4 0.5 0.5 0.6 0.3 0.4 1.0
Medication: Seretide 50 evohaler 0.1 0.1 1.0 -0.2 0.3 -0.7 -0.4 -0.2 -0.2 -0.2 0.2 0.1 -0.4 -0.5 1.0 -0.2 0.2 -0.2 0.6 0.2 -0.2 -0.1 -0.1 -0.3 0.0 -0.2 -0.2 -0.4 -0.3 -0.1 0.2 -0.3 -0.2 -0.0 -0.2 -0.1 -0.1 0.2 -0.4 -0.2
Mean time to correctly identify matches 1.7 3.3 4.7 2.0 1.1 1.7 2.1 1.9 1.9 -0.4 1.2 0.8 1.8 1.9 1.7 -2.0 -2.0 2.0 -2.0 -2.0 1.5 1.9 1.8 2.2 1.9 2.0 1.9 1.8 1.8 1.8 1.9 2.0 2.0 1.8 2.0 1.9 2.0 1.3 1.9 1.9
Heart disease (mother) 0.2 0.3 2.0 0.3 -0.1 0.5 0.4 0.5 0.6 -1.4 0.1 -0.4 0.7 0.3 0.9 -0.7 -0.3 0.5 0.0 -0.5 0.7 0.5 0.9 0.4 0.5 0.3 0.5 0.2 0.4 0.3 0.7 0.5 0.4 0.5 0.5 0.5 0.4 0.8 0.5 0.2
Reproduciblity of spirometry measurement using ERS/ATS criteria 2.6 3.2 5.5 -2.2 -1.6 -1.7 -1.9 -1.9 -1.9 -1.7 -1.4 -0.9 -2.0 -1.8 -0.5 1.7 1.5 -1.9 1.4 1.9 -1.7 -1.7 -1.9 -2.1 -1.8 -1.6 -1.9 -1.4 -1.6 -2.4 -2.2 -1.9 -1.9 -1.6 -1.9 -1.8 -2.1 -1.3 -1.7 -2.0
Whole body fat mass 0.3 1.2 3.4 -1.4 -1.3 -1.0 -1.2 -1.2 -1.2 -1.9 -0.4 -1.3 -0.9 -1.1 0.1 0.9 1.1 -1.1 1.1 1.1 -0.7 -1.1 -1.3 -1.4 -1.0 -1.0 -1.2 -1.2 -0.6 -0.8 -1.1 -1.0 -1.1 -0.7 -1.1 -1.1 -1.2 -0.5 -1.2 -0.6
Leg fat mass (right) 0.2 0.6 2.9 -1.1 -1.0 -1.0 -0.9 -0.8 -0.8 -1.7 -0.1 -1.0 -0.7 -0.8 0.8 0.5 0.8 -0.7 0.7 0.8 -0.3 -0.7 -0.9 -1.1 -0.6 -0.6 -0.8 -0.8 -0.2 -0.5 -0.6 -0.7 -0.7 -0.3 -0.8 -0.7 -0.9 -0.1 -0.8 -0.1
Arm predicted mass (right) 0.0 0.1 1.3 -0.1 -0.1 0.5 -0.1 -0.3 -0.2 -1.1 0.8 -0.4 -0.1 -0.2 0.5 -0.2 -0.1 -0.2 0.3 0.2 -0.2 -0.2 -0.3 -0.2 0.3 -0.1 -0.3 -0.4 0.0 0.3 0.2 -0.2 -0.2 -0.0 -0.2 -0.2 -0.1 0.3 -0.3 0.3
Pulse rate, automated reading 0.3 1.0 5.4 0.5 -0.5 1.3 -0.5 -0.4 -0.6 2.3 -0.8 -2.3 0.3 -0.3 -0.9 1.2 -0.1 -0.4 0.2 0.5 -1.6 -0.9 -1.3 -0.8 -1.8 -0.9 -0.4 -0.8 -0.8 0.2 -0.9 -0.4 -0.5 -0.7 -0.4 -0.7 -0.2 -2.3 -0.7 0.0
Alcohol intake frequency. 0.1 0.1 0.8 -0.6 -0.1 0.1 0.1 -0.1 -0.2 -0.1 0.4 0.9 -0.1 -0.2 0.9 -0.3 0.1 -0.1 0.2 0.2 0.2 0.2 0.3 -0.0 0.5 0.2 -0.1 0.1 0.1 -0.7 -0.1 -0.2 -0.1 0.1 -0.1 -0.0 -0.4 0.7 -0.1 -0.5
Comparative height size at age 10 0.0 0.2 2.2 0.0 0.5 1.5 0.3 0.2 0.1 0.4 0.3 0.7 0.2 0.3 -0.5 -0.3 -0.4 0.2 0.1 -0.1 0.2 0.3 0.2 0.3 0.8 0.4 0.2 0.1 0.0 0.1 0.2 0.2 0.1 0.2 0.2 0.2 0.1 0.6 0.1 0.1
Number of full sisters 1.5 1.9 5.4 -2.1 -1.3 -1.5 -1.5 -1.4 -1.3 0.6 -1.4 0.4 -1.0 -1.4 -1.9 1.5 1.0 -1.3 1.3 1.4 -1.0 -1.2 -1.2 -1.5 -1.0 -1.1 -1.3 -1.0 -1.0 -2.2 -1.6 -1.3 -1.3 -1.2 -1.4 -1.2 -1.6 -0.6 -1.1 -2.3
Suffer from ‘nerves’ 0.2 0.4 1.5 -0.9 -0.6 -0.7 -0.6 -0.7 -0.6 -1.1 -0.4 -0.1 -0.8 -0.7 0.2 0.4 0.5 -0.6 0.4 0.7 -0.5 -0.5 -0.1 -0.3 -0.2 -0.4 -0.6 -0.1 -0.4 -1.2 -0.5 -0.5 -0.5 -0.6 -0.8 -0.5 -0.7 -0.2 -0.4 -1.1
Overall health rating 1.0 2.2 5.2 -1.8 -1.6 -0.9 -1.5 -1.6 -1.8 -1.0 -0.9 -1.0 -1.4 -1.3 -0.5 1.7 1.3 -1.4 1.7 1.7 -1.3 -1.5 -1.4 -1.6 -1.4 -1.5 -1.5 -1.2 -1.1 -1.9 -1.9 -1.4 -1.6 -1.5 -1.6 -1.5 -1.5 -1.2 -1.5 -2.3
Chest pain or discomfort 0.6 0.8 5.9 -1.1 -1.0 -0.2 -1.1 -1.1 -0.8 -2.4 -0.2 0.1 -1.0 -1.1 0.8 0.5 0.8 -1.0 1.1 0.9 -0.2 -0.8 -0.7 -0.9 -0.2 -0.9 -1.0 -1.1 -0.9 -0.7 -0.5 -0.9 -0.9 -0.7 -1.1 -0.8 -1.0 0.3 -0.9 -0.5
Had major operations 1.1 1.3 2.3 -1.4 -1.2 -1.4 -1.4 -1.2 -1.1 0.0 -1.2 -0.3 -1.1 -1.1 -0.5 1.4 1.2 -1.3 0.7 1.1 -0.7 -1.1 -1.1 -1.2 -1.2 -1.0 -1.2 -0.8 -0.8 -1.3 -1.5 -1.2 -1.2 -1.1 -1.2 -1.1 -1.4 -0.9 -1.0 -1.0
Age at last live birth 0.6 0.9 2.1 0.6 0.9 0.8 0.5 1.0 1.1 0.3 1.4 0.9 1.0 0.9 0.4 -1.1 -1.3 0.9 -0.7 -1.0 0.7 1.1 1.2 0.8 0.9 1.0 0.9 1.3 0.7 0.2 0.8 1.0 1.0 1.1 1.0 1.0 0.7 1.1 1.2 -0.1
Family relationship satisfaction 1.2 1.5 6.4 1.6 1.3 1.2 1.1 1.3 1.1 2.5 0.5 -0.0 1.4 1.5 -0.3 -1.0 -1.1 1.3 -1.0 -1.2 0.7 1.0 0.9 1.3 0.9 1.0 1.3 0.8 0.8 1.9 1.4 1.3 1.3 1.0 1.3 1.1 1.5 0.4 1.0 1.6
Leg pain on walking 8.4 10.5 13.6 -3.6 -3.4 -3.0 -3.3 -3.5 -3.4 -2.9 -3.3 -2.4 -3.2 -3.4 -0.9 3.1 3.3 -3.5 3.5 3.4 -3.2 -3.2 -3.1 -3.4 -3.0 -3.2 -3.5 -3.4 -3.7 -3.3 -3.2 -3.5 -3.4 -3.2 -3.5 -3.4 -3.6 -2.5 -3.4 -3.1
Qualifications: NVQ or HND or HNC or equivalent 1.8 2.1 4.0 -1.9 -1.1 -1.6 -1.7 -1.6 -1.5 0.7 -1.6 0.3 -1.4 -1.4 -0.9 1.4 1.5 -1.5 1.5 1.6 -1.4 -1.3 -1.1 -1.5 -1.3 -1.2 -1.5 -1.2 -1.4 -1.9 -1.7 -1.5 -1.5 -1.4 -1.6 -1.4 -2.0 -1.0 -1.4 -1.9
Commuting to job workplace: Car/motor vehicle 0.3 0.4 2.0 -0.0 0.5 0.9 0.5 0.4 0.7 -0.9 0.7 1.0 -0.4 0.3 1.4 -0.6 -0.8 0.4 -0.6 -0.5 0.7 0.5 0.6 0.5 0.7 0.6 0.4 0.8 0.2 -0.3 0.3 0.5 0.5 0.5 0.3 0.5 0.2 0.7 0.8 -0.1
Illness, injury, bereavement, stress in last 2 years 1.0 1.2 2.6 -1.4 -1.1 -1.4 -1.2 -1.2 -1.1 -1.1 -1.0 0.4 -1.1 -1.3 -0.7 1.1 1.0 -1.2 1.1 1.1 -1.0 -0.9 -0.8 -1.1 -0.9 -0.9 -1.1 -0.7 -0.9 -1.6 -1.1 -1.1 -1.1 -0.9 -1.1 -1.0 -1.4 -0.6 -0.9 -1.6
Medication: Aspirin 1.2 1.6 6.3 -0.7 -2.0 -0.3 -1.2 -1.2 -1.2 -2.4 -1.1 -2.5 -0.9 -1.0 -1.0 1.2 1.3 -1.1 1.4 1.2 -0.9 -1.3 -1.3 -1.2 -1.1 -1.3 -1.1 -1.7 -1.1 -0.1 -1.0 -1.0 -1.2 -1.2 -1.2 -1.2 -0.9 -1.1 -1.4 -0.4
Supplements: Vitamin C 1.3 1.5 3.8 1.5 1.3 1.3 1.3 1.2 1.2 1.1 1.1 0.8 1.5 1.1 0.8 -1.2 -1.1 1.3 -1.0 -1.2 1.0 1.2 1.3 1.3 1.2 1.0 1.3 0.7 0.7 1.9 1.8 1.3 1.2 1.2 1.2 1.2 1.4 1.1 0.9 1.9
Knee pain experienced in last month 0.0 0.1 0.6 0.1 0.8 -0.3 -0.5 -0.0 -0.2 0.1 -0.2 0.5 -0.2 0.0 0.6 0.0 0.1 -0.0 0.2 0.1 -0.3 -0.0 0.0 -0.0 -0.0 -0.1 -0.0 -0.2 -0.1 0.4 0.3 -0.0 -0.1 0.1 -0.1 -0.1 -0.0 0.1 -0.2 0.7
Hypertension (Self-reported) 0.2 0.5 5.8 -0.6 -0.8 1.0 -0.7 -0.6 -0.5 -2.0 0.6 -0.6 -0.6 -0.4 2.4 0.3 -0.1 -0.5 0.4 0.5 -0.5 -0.3 -0.4 -0.5 -0.3 -0.3 -0.6 -0.5 -0.5 -0.6 -0.7 -0.6 -0.5 -0.3 -0.5 -0.5 -0.7 -0.3 -0.5 -0.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 2.1 2.5 4.3 1.8 1.5 1.5 1.8 1.8 1.5 0.7 2.0 0.7 1.9 2.1 0.1 -1.0 -1.5 1.8 -1.9 -1.6 1.6 1.6 1.2 1.4 0.9 1.5 1.8 1.7 1.7 2.0 1.1 1.7 1.6 1.6 1.8 1.6 1.6 0.9 1.6 1.8
Illnesses of father: Heart disease 1.9 2.7 7.2 -0.8 -1.6 -1.0 -1.6 -1.4 -1.8 -1.9 -1.5 -2.7 -1.4 -1.3 -2.0 1.5 1.8 -1.5 2.0 1.6 -1.5 -1.8 -1.9 -1.7 -2.0 -1.9 -1.5 -1.8 -1.0 -0.7 -1.6 -1.5 -1.6 -1.7 -1.4 -1.7 -1.0 -2.1 -1.9 -1.3
Illnesses of siblings: Diabetes 2.1 2.6 4.5 -1.7 -1.6 -1.4 -2.1 -1.8 -1.8 -0.4 -1.9 -0.5 -1.5 -1.8 -1.4 1.6 1.6 -1.8 1.9 1.8 -1.5 -1.5 -1.1 -1.6 -1.4 -1.7 -1.7 -1.7 -1.4 -1.5 -1.3 -1.7 -1.8 -1.6 -1.8 -1.6 -1.9 -1.1 -1.8 -1.9
Smoking status: Previous 0.1 0.1 1.6 -0.4 -0.3 0.2 0.0 -0.1 0.1 -0.8 -0.1 0.6 -0.3 -0.1 1.3 -0.4 -0.1 -0.1 0.4 0.0 0.3 0.1 0.0 -0.2 0.5 0.1 -0.1 -0.1 -0.2 -0.2 -0.0 -0.1 -0.1 0.2 -0.1 0.0 -0.2 0.8 -0.0 -0.3
Forced expiratory volume in 1-second (FEV1), predicted 0.0 0.1 0.4 0.5 0.4 0.3 0.2 0.1 0.1 0.1 0.2 -0.6 0.0 0.2 -0.3 0.2 -0.1 0.1 -0.1 -0.1 0.0 -0.1 -0.3 0.1 -0.1 -0.1 0.1 0.1 0.1 0.4 0.0 0.2 0.1 -0.0 0.1 -0.0 0.5 -0.2 0.1 0.3
Whole body fat-free mass 0.0 0.1 0.6 -0.2 0.0 0.5 -0.2 -0.4 -0.3 -0.8 0.7 -0.2 -0.2 -0.3 0.6 -0.1 0.0 -0.3 0.4 0.3 -0.3 -0.3 -0.4 -0.2 0.2 -0.2 -0.3 -0.5 -0.1 0.3 0.1 -0.3 -0.3 -0.1 -0.3 -0.3 -0.2 0.2 -0.4 0.3
Leg fat-free mass (right) 0.0 0.2 0.9 -0.3 -0.2 0.4 -0.4 -0.5 -0.5 -1.0 0.5 -0.5 -0.3 -0.4 0.6 0.2 0.2 -0.5 0.5 0.5 -0.4 -0.5 -0.7 -0.5 -0.1 -0.4 -0.5 -0.7 -0.2 0.1 -0.3 -0.4 -0.5 -0.3 -0.4 -0.5 -0.3 -0.1 -0.6 0.1
Arm fat percentage (left) 0.5 1.9 3.3 -1.8 -1.6 -1.4 -1.7 -1.6 -1.6 -1.7 -0.8 -1.4 -1.2 -1.5 0.0 1.3 1.4 -1.4 1.4 1.5 -0.9 -1.4 -1.5 -1.8 -1.4 -1.3 -1.5 -1.4 -0.9 -1.2 -1.5 -1.4 -1.4 -1.0 -1.5 -1.4 -1.7 -0.8 -1.5 -1.0
Average weekly red wine intake 0.0 0.1 0.4 0.2 -0.0 -0.2 0.3 0.0 0.0 0.0 -0.2 -0.6 0.0 0.3 -0.1 0.0 0.3 0.0 0.1 -0.0 0.2 -0.2 -0.4 -0.0 -0.2 -0.2 -0.0 -0.2 0.5 0.5 -0.2 -0.0 -0.0 -0.1 -0.0 -0.1 0.3 -0.4 -0.0 0.1
Handedness (chirality/laterality): Left-handed 0.8 0.9 4.1 -0.3 -0.4 -0.7 -0.7 -0.7 -0.7 0.8 -1.2 -1.7 -0.8 -0.7 -1.4 1.1 1.0 -0.7 0.8 0.7 -1.1 -1.1 -1.1 -0.7 -1.4 -1.1 -0.7 -1.1 -0.7 -0.3 -0.9 -0.7 -0.8 -1.2 -0.7 -1.0 -0.4 -2.0 -0.9 -0.8
Mood swings 0.2 0.3 0.7 -0.5 -0.1 -0.6 -0.6 -0.6 -0.6 0.0 -0.4 -0.5 -0.4 -0.7 -0.0 0.4 0.3 -0.6 0.5 0.6 -0.8 -0.7 -0.6 -0.5 -0.7 -0.7 -0.6 -0.4 -0.2 -0.4 -0.3 -0.5 -0.6 -0.6 -0.6 -0.6 -0.5 -0.7 -0.5 -0.5
Loneliness, isolation 1.2 1.7 3.1 1.7 1.1 1.4 1.5 1.3 1.5 0.2 1.0 -0.0 1.0 1.3 0.4 -1.3 -1.4 1.4 -1.5 -1.4 1.5 1.1 1.1 1.4 1.1 1.1 1.4 1.3 1.7 1.4 1.3 1.2 1.5 1.2 1.3 1.3 1.8 0.7 1.4 1.3
Long-standing illness, disability or infirmity 0.2 0.3 0.9 0.4 0.0 1.0 0.3 0.3 0.3 -0.7 0.8 -0.3 0.2 0.5 0.7 -0.7 -0.2 0.4 -0.3 -0.3 0.7 0.3 0.4 0.5 0.8 0.3 0.3 0.0 0.5 0.9 0.6 0.3 0.3 0.4 0.2 0.3 0.5 0.7 0.2 0.9
Ever had bowel cancer screening 1.7 2.0 5.1 2.2 1.5 2.0 1.4 1.4 1.3 1.1 0.9 0.0 1.5 1.5 1.3 -1.4 -1.4 1.5 -1.5 -1.3 0.8 1.1 1.1 1.5 0.8 1.0 1.5 0.9 1.5 2.3 1.7 1.6 1.3 1.3 1.4 1.3 2.0 0.3 1.1 2.2
Diabetes diagnosed by doctor 5.4 8.9 12.4 -3.2 -3.2 -3.0 -3.5 -3.2 -3.2 -1.5 -3.1 -1.7 -3.0 -3.3 -1.6 3.0 3.3 -3.3 3.1 3.2 -2.8 -3.0 -2.9 -3.2 -2.8 -3.0 -3.3 -3.0 -2.9 -2.9 -2.9 -3.2 -3.2 -3.0 -3.2 -3.2 -3.3 -2.3 -3.2 -2.6
Ever had stillbirth, spontaneous miscarriage or termination 3.7 4.0 6.8 1.9 1.9 2.1 2.0 2.1 1.7 1.5 2.1 1.2 2.3 2.2 1.9 -1.8 -1.9 2.2 -2.0 -1.9 2.3 2.1 2.1 2.0 1.9 2.1 2.1 2.3 2.6 1.6 1.7 2.2 2.0 2.1 2.0 2.1 2.0 2.1 2.0 1.6
Friendships satisfaction 0.2 0.2 2.0 0.3 -0.2 -0.6 -0.1 -0.2 -0.4 1.4 -0.3 -0.4 -0.4 -0.2 -0.6 0.3 0.6 -0.2 0.2 0.3 -0.5 -0.4 -0.7 -0.2 -0.5 -0.4 -0.2 -0.5 -0.5 0.3 -0.1 -0.3 -0.2 -0.4 -0.2 -0.4 0.1 -0.6 -0.5 0.5
Qualifications: nursing, teaching 1.9 2.9 5.7 2.2 1.9 1.7 2.0 1.8 1.9 1.4 1.7 0.2 1.9 1.9 1.0 -1.6 -1.6 1.8 -1.9 -1.8 1.4 1.5 1.2 1.7 1.3 1.5 1.7 1.5 1.0 2.3 1.7 1.9 1.9 1.7 1.8 1.7 2.1 0.9 1.7 2.4
Commuting to job workplace: Walk 2.4 2.6 3.9 1.5 1.5 1.6 1.6 1.7 1.7 0.3 1.6 1.2 1.6 1.7 1.3 -1.8 -1.7 1.6 -1.5 -1.7 1.8 1.7 1.6 1.5 1.8 1.7 1.6 1.2 1.7 1.8 1.8 1.4 1.6 1.9 1.7 1.7 1.5 2.0 1.5 1.9
Eye problems/disorders: Cataract 0.2 0.2 1.0 -0.7 -0.8 -0.4 -0.1 -0.4 -0.3 -1.0 -0.9 -0.5 -0.5 -0.7 -0.0 0.5 0.4 -0.4 0.1 0.4 -0.1 -0.3 -0.1 -0.3 -0.1 -0.2 -0.4 -0.2 -0.2 -0.9 -0.2 -0.4 -0.4 -0.4 -0.5 -0.3 -0.6 0.1 -0.3 -0.5
Mouth/teeth dental problems: Mouth ulcers 2.5 4.0 6.5 2.0 1.6 1.6 2.1 2.2 2.2 1.5 1.9 0.7 2.6 1.8 1.6 -1.9 -1.9 2.2 -2.1 -2.2 2.1 2.1 1.9 1.9 1.8 2.1 2.2 2.0 1.6 1.7 2.1 2.2 2.2 2.2 2.2 2.2 2.2 2.0 2.1 2.3
Medication for cholesterol 2.3 3.5 9.5 1.7 2.1 1.1 2.1 1.8 1.9 3.1 1.3 2.3 2.3 1.6 -0.2 -1.7 -1.6 1.9 -1.7 -1.9 1.7 1.9 1.9 1.9 1.8 1.8 1.8 2.0 1.5 1.7 2.1 1.9 1.9 1.8 1.9 1.9 1.7 1.9 1.9 1.8
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.2 0.3 1.4 0.1 -0.6 -0.0 -0.3 -0.4 -0.3 0.6 -0.0 -1.1 -0.1 -0.2 -1.1 0.6 0.4 -0.3 0.3 0.3 -0.6 -0.6 -0.6 -0.3 -0.8 -0.6 -0.4 -0.6 -0.2 0.2 -0.5 -0.3 -0.3 -0.6 -0.4 -0.5 -0.1 -1.2 -0.4 -0.2
Back pain experienced in last month 0.5 0.7 3.8 0.1 0.8 0.2 0.9 0.6 0.5 0.9 0.6 1.7 0.4 0.7 1.9 -0.8 -0.2 0.7 -0.6 -0.5 1.4 0.8 0.7 0.6 1.3 1.0 0.6 0.6 0.7 0.5 0.5 0.4 0.6 0.9 0.6 0.7 0.4 1.7 0.5 0.8
Mineral and other dietary supplements 0.1 0.2 2.5 0.0 0.0 -0.6 0.3 0.1 -0.1 1.6 -0.1 -0.5 -0.0 0.1 -1.0 0.3 0.2 -0.0 -0.4 0.0 0.0 -0.2 -0.3 -0.2 -0.7 -0.1 0.0 0.4 0.2 -0.7 -0.6 0.1 -0.0 -0.2 0.1 -0.1 0.1 -0.6 0.1 -0.5
Breast cancer (self-reported) 3.2 3.9 5.9 -2.3 -1.6 -2.2 -2.2 -2.1 -2.0 -0.4 -2.4 -0.1 -2.2 -1.9 -1.2 2.1 2.1 -2.1 2.0 2.0 -1.8 -1.9 -1.8 -2.0 -1.7 -1.8 -2.1 -2.0 -2.1 -2.1 -2.2 -2.2 -2.0 -2.0 -2.0 -2.0 -2.3 -1.5 -2.0 -2.2
Asthma (self-reported) 1.4 2.9 7.3 1.6 1.4 1.5 1.5 1.6 1.5 0.2 2.4 0.8 1.5 1.4 2.7 -2.3 -1.5 1.6 -1.4 -1.6 2.0 1.7 1.6 1.5 1.8 1.5 1.6 1.4 1.8 1.7 1.9 1.6 1.6 1.8 1.6 1.7 1.8 2.2 1.5 1.8
Osteoporosis (self-reported) 1.5 1.8 5.6 1.1 1.9 1.4 1.2 1.3 1.1 2.4 1.4 2.2 1.2 1.3 0.8 -1.5 -1.1 1.2 -1.3 -1.1 1.4 1.4 1.2 1.3 1.6 1.4 1.2 1.7 1.1 0.8 1.2 1.2 1.2 1.3 1.2 1.2 1.2 1.6 1.3 0.9
Osteoarthritis (self-reported) 0.3 0.4 1.1 0.1 0.4 0.3 0.4 0.5 0.5 -0.4 1.0 0.8 0.5 0.4 1.1 -0.8 -0.5 0.5 -0.2 -0.5 0.4 0.7 0.9 0.7 0.9 0.6 0.5 0.6 0.3 0.3 0.7 0.6 0.6 0.6 0.5 0.6 0.4 0.8 0.5 0.3
Medication: Aspirin 1.1 1.4 5.5 -0.6 -1.9 -0.2 -1.2 -1.1 -1.1 -2.3 -1.0 -2.4 -0.9 -1.0 -0.9 1.1 1.2 -1.1 1.3 1.1 -1.0 -1.3 -1.2 -1.1 -1.1 -1.2 -1.1 -1.5 -1.1 -0.3 -0.9 -1.0 -1.1 -1.2 -1.1 -1.2 -0.9 -1.2 -1.3 -0.5
Medication: Gliclazide 0.3 0.4 2.2 0.5 -0.0 0.5 0.2 0.4 0.5 -0.6 0.8 0.8 0.4 0.2 1.5 -1.0 -0.1 0.5 -0.4 -0.4 0.7 0.6 0.7 0.6 0.8 0.5 0.5 0.5 0.6 0.6 0.9 0.5 0.5 0.6 0.4 0.5 0.6 0.9 0.4 0.9
Illnesses of father: None of the above (group 1) 0.4 0.5 3.4 -0.2 0.3 -0.1 0.7 0.4 0.9 0.0 0.5 1.8 0.3 0.1 0.9 -0.7 -0.8 0.4 -0.9 -0.7 1.0 0.8 0.9 0.6 1.0 0.9 0.4 0.6 0.5 -0.3 0.7 0.3 0.6 0.8 0.4 0.7 -0.0 1.3 0.9 0.4
Smoking status: Current 0.2 0.3 1.9 -0.9 -1.3 -0.9 -0.4 -0.6 -0.3 -1.4 -0.5 -0.4 -0.4 -0.7 -0.2 0.4 0.3 -0.6 0.2 0.4 0.0 -0.2 -0.0 -0.6 -0.2 -0.3 -0.5 -0.3 -0.2 -0.4 -0.2 -0.6 -0.4 -0.1 -0.6 -0.3 -1.0 0.4 -0.4 -0.3
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.2 0.4 1.1 -0.5 -0.7 -0.9 -0.7 -0.5 -0.4 -1.0 -0.8 -0.7 -0.6 -0.5 -0.9 0.5 0.5 -0.5 0.4 0.4 -0.7 -0.5 -0.2 -0.4 -0.6 -0.5 -0.6 -0.1 -0.7 -0.9 -0.5 -0.6 -0.4 -0.6 -0.5 -0.5 -0.5 -0.6 -0.3 -0.9
Whole body water mass 0.0 0.1 0.5 -0.2 -0.0 0.5 -0.3 -0.4 -0.3 -0.7 0.7 -0.3 -0.2 -0.3 0.5 -0.1 0.0 -0.3 0.4 0.3 -0.3 -0.3 -0.4 -0.2 0.1 -0.2 -0.4 -0.6 -0.1 0.3 0.0 -0.3 -0.3 -0.2 -0.3 -0.3 -0.2 0.1 -0.5 0.3
Leg predicted mass (right) 0.0 0.2 0.9 -0.4 -0.3 0.4 -0.5 -0.6 -0.6 -1.0 0.4 -0.5 -0.3 -0.5 0.5 0.2 0.3 -0.5 0.6 0.5 -0.4 -0.5 -0.8 -0.5 -0.2 -0.5 -0.5 -0.7 -0.3 0.0 -0.3 -0.5 -0.5 -0.4 -0.5 -0.5 -0.4 -0.2 -0.7 0.0
Arm fat mass (left) 0.4 1.7 3.9 -1.6 -1.5 -1.1 -1.5 -1.5 -1.4 -2.0 -0.6 -1.4 -1.2 -1.4 0.1 1.1 1.2 -1.4 1.3 1.4 -0.9 -1.3 -1.5 -1.6 -1.2 -1.3 -1.4 -1.5 -0.8 -1.0 -1.2 -1.3 -1.3 -1.0 -1.4 -1.3 -1.5 -0.8 -1.5 -0.8
Number of self-reported non-cancer illnesses 0.2 0.4 1.3 -0.6 -0.8 -0.0 -0.6 -0.7 -0.8 -1.1 0.2 -0.5 -0.5 -0.5 0.7 0.5 0.8 -0.5 0.6 0.8 -0.4 -0.5 -0.6 -0.6 -0.2 -0.5 -0.6 -0.8 -0.8 -0.1 -0.4 -0.5 -0.6 -0.4 -0.7 -0.6 -0.5 -0.1 -0.8 0.2
Average weekly champagne plus white wine intake 0.1 0.1 1.4 0.5 0.3 0.3 0.0 0.3 0.5 1.2 0.4 0.2 0.0 0.1 -0.9 -0.3 -0.1 0.2 -0.1 -0.4 0.6 0.2 0.2 0.0 0.0 0.1 0.3 0.1 0.1 0.4 0.2 0.1 0.4 0.3 0.3 0.2 0.3 0.3 0.3 0.3
Miserableness 0.7 1.2 3.2 0.6 1.1 0.7 0.9 0.9 1.0 1.2 1.4 1.8 1.0 1.0 1.2 -1.2 -1.2 1.1 -0.9 -1.0 1.1 1.1 1.2 0.9 0.9 1.1 1.0 1.6 1.5 0.4 0.8 1.1 1.1 1.1 0.9 1.1 0.8 1.1 1.4 0.1
Guilty feelings 0.5 0.7 3.1 1.8 0.9 1.7 0.6 0.6 1.0 0.8 0.8 -1.3 0.4 0.5 0.7 -0.9 -0.6 0.7 -0.8 -0.8 0.4 0.1 0.2 0.9 0.2 0.1 0.7 0.5 0.2 1.3 0.9 0.7 0.8 0.2 0.6 0.5 1.6 -0.5 0.8 1.4
Wears glasses or contact lenses 1.9 2.2 3.7 -1.9 -1.1 -1.5 -1.5 -1.8 -1.6 -1.3 -0.8 0.0 -1.6 -1.6 -0.3 1.2 1.7 -1.7 1.5 1.7 -1.2 -1.6 -1.5 -1.6 -1.0 -1.5 -1.7 -1.6 -1.6 -1.5 -1.5 -1.6 -1.7 -1.6 -1.8 -1.6 -1.7 -0.8 -1.6 -1.4
Ever taken oral contraceptive pill 0.2 0.2 1.0 -0.0 -0.1 0.0 -0.5 -0.5 -0.1 -1.0 -0.6 -0.7 -0.7 -0.5 -0.4 0.5 0.1 -0.4 0.3 0.3 -0.5 -0.6 -0.5 -0.3 -0.7 -0.6 -0.4 -0.6 -0.2 -0.1 -0.3 -0.5 -0.3 -0.5 -0.5 -0.4 -0.2 -0.9 -0.4 0.2
Hearing aid user 0.2 0.2 0.6 0.7 0.4 0.1 0.6 0.4 0.1 0.2 0.2 0.0 0.6 0.6 -0.8 -0.3 -0.1 0.6 -0.2 -0.3 -0.1 0.2 0.3 0.5 0.1 0.2 0.5 0.2 0.5 0.7 0.5 0.6 0.3 0.3 0.4 0.3 0.6 -0.2 0.2 0.6
Mother’s age at death 0.1 0.2 1.7 0.0 0.2 0.9 0.3 0.1 0.1 -1.3 -0.1 0.6 -0.2 0.1 0.3 -0.5 -0.5 0.1 -0.2 -0.1 0.3 0.3 0.6 0.4 0.6 0.2 0.1 0.3 0.4 0.3 0.6 0.1 0.2 0.2 0.1 0.2 0.1 0.6 0.2 0.3
Financial situation satisfaction 5.3 6.6 8.4 -2.8 -2.1 -2.3 -2.7 -2.8 -2.8 -1.6 -2.1 -1.2 -2.8 -2.7 -1.1 2.6 2.5 -2.7 2.9 2.8 -2.9 -2.7 -2.7 -2.8 -2.6 -2.7 -2.7 -2.8 -2.8 -2.3 -2.5 -2.8 -2.7 -2.6 -2.8 -2.8 -2.7 -2.4 -2.8 -2.2
Tinnitus: Yes, now most or all of the time 0.0 0.0 0.3 0.3 0.4 0.6 0.0 0.1 -0.1 -0.5 0.5 0.3 -0.1 0.3 -0.1 0.0 -0.1 0.0 0.1 0.0 -0.2 -0.1 0.0 0.2 0.2 -0.0 0.1 -0.3 0.1 0.4 0.1 0.0 -0.1 -0.1 0.1 -0.1 0.1 -0.0 -0.2 0.2
Commuting to job workplace: Public transport 1.0 1.2 2.0 -0.8 -1.2 -0.9 -1.1 -1.1 -1.2 -0.6 -1.4 -1.2 -0.9 -1.0 -0.5 1.2 1.1 -1.1 1.0 1.1 -1.4 -1.2 -1.4 -1.1 -1.2 -1.2 -1.1 -1.3 -1.2 -0.7 -1.2 -1.3 -1.2 -1.2 -1.0 -1.2 -1.0 -1.3 -1.3 -0.7
Eye problems/disorders: Glaucoma 2.0 2.3 8.1 1.0 1.5 1.8 1.2 1.2 1.3 0.6 1.4 2.8 1.2 1.1 2.1 -1.7 -1.4 1.3 -1.5 -1.3 1.8 1.5 1.6 1.4 1.8 1.5 1.3 1.5 1.7 1.1 1.7 1.4 1.4 1.6 1.2 1.4 1.2 2.1 1.4 1.6
Medication: Blood pressure 0.2 0.3 4.9 0.5 0.3 1.6 -0.1 0.3 0.2 -1.0 0.7 -0.7 -0.0 0.6 2.2 -0.4 -0.7 0.3 -0.4 -0.2 0.0 0.2 -0.0 0.3 0.2 0.3 0.3 0.1 0.3 0.4 -0.1 0.2 0.2 0.3 0.3 0.2 0.4 -0.1 0.2 0.4
Pain type(s) experienced in last month: Hip pain 0.1 0.2 0.5 0.7 -0.2 0.5 0.3 0.4 0.5 0.4 0.5 -0.4 0.5 0.5 -0.1 -0.2 -0.3 0.5 -0.5 -0.4 0.4 0.3 0.2 0.4 0.2 0.3 0.4 0.3 0.2 0.6 0.2 0.5 0.4 0.3 0.3 0.4 0.6 0.0 0.4 0.4
Supplements: Fish oil (including cod liver oil) 0.3 0.3 2.2 -0.3 -0.4 0.1 -0.8 -0.6 -0.5 -1.5 -0.5 -0.1 -0.6 -0.5 -0.0 0.2 0.5 -0.5 0.9 0.5 -0.5 -0.5 -0.4 -0.3 0.1 -0.5 -0.5 -1.2 -0.8 0.6 0.0 -0.6 -0.5 -0.4 -0.5 -0.5 -0.5 -0.1 -0.8 0.2
High cholesterol (Self-reported) 0.2 0.3 2.3 -0.3 -0.5 0.1 -0.2 -0.4 -0.6 -1.4 -0.4 -1.5 -0.4 -0.3 0.5 0.4 0.6 -0.4 0.5 0.5 -0.3 -0.5 -0.5 -0.4 -0.2 -0.4 -0.4 -0.8 -0.5 0.0 -0.5 -0.3 -0.5 -0.5 -0.5 -0.5 -0.2 -0.4 -0.7 -0.2
Medication: Bendroflumethiazide 0.4 0.6 3.7 0.6 0.6 1.6 0.7 0.6 0.7 -0.2 1.2 -0.4 0.7 0.8 1.9 -0.9 -1.0 0.6 -0.7 -0.7 0.5 0.7 0.5 0.6 0.7 0.8 0.6 0.5 0.7 0.6 0.4 0.6 0.6 0.8 0.7 0.6 0.5 0.5 0.6 0.7
Medication: Paracetamol 0.7 1.0 2.1 1.0 0.9 0.8 0.7 1.0 0.9 -0.3 1.4 1.2 1.0 0.9 1.1 -1.0 -0.9 1.0 -1.2 -0.9 1.2 1.0 1.1 1.0 0.9 0.8 1.0 1.1 1.4 0.9 1.1 1.1 1.0 1.0 1.0 1.0 1.1 1.0 1.0 1.3
Medication: Lisinopril 0.1 0.1 0.6 -0.1 -0.3 -0.0 -0.2 -0.2 -0.2 -0.8 -0.8 -0.6 -0.1 -0.3 0.3 0.3 0.4 -0.2 0.1 0.2 -0.1 -0.3 -0.3 -0.3 -0.3 -0.3 -0.2 -0.4 -0.4 -0.2 -0.3 -0.1 -0.3 -0.3 -0.2 -0.3 -0.2 -0.2 -0.3 0.1
Medication: Atorvastatin 2.7 3.3 7.6 -1.4 -1.7 -1.3 -1.8 -1.8 -1.9 -2.8 -2.0 -2.4 -1.8 -1.6 -0.9 1.8 2.0 -1.8 1.6 1.9 -1.8 -2.0 -2.1 -1.8 -1.9 -2.0 -1.8 -1.9 -1.6 -1.5 -2.0 -1.7 -1.9 -1.9 -1.8 -1.9 -1.4 -2.0 -1.9 -1.3
Illnesses of father: High blood pressure 0.8 1.0 5.0 -0.9 -1.1 -0.1 -1.0 -1.0 -1.3 -2.2 -0.1 -0.7 -1.2 -0.9 0.3 0.8 0.9 -0.9 1.1 1.2 -1.2 -0.8 -0.9 -1.1 -0.8 -0.8 -0.9 -0.9 -1.2 -0.7 -0.9 -0.9 -1.1 -0.8 -1.0 -1.0 -1.1 -0.5 -1.2 -0.6
Alcohol drinker status: Never 0.9 1.0 2.1 -0.9 -0.7 -1.4 -0.8 -1.1 -1.0 -0.4 -1.0 0.0 -1.1 -1.3 -0.8 1.0 1.4 -1.1 1.1 1.1 -0.7 -1.0 -0.9 -1.0 -0.8 -1.1 -1.1 -1.2 -1.3 -0.8 -0.8 -1.2 -1.1 -1.1 -1.1 -1.1 -0.9 -0.7 -1.2 -0.8
Ever smoked 0.7 1.2 4.2 -1.7 -1.8 -1.1 -0.9 -1.2 -0.9 -2.0 -1.2 -0.6 -1.2 -1.0 -0.2 0.7 0.9 -1.1 1.3 1.0 -0.4 -0.8 -0.9 -1.3 -0.5 -0.8 -1.1 -1.2 -1.0 -0.9 -1.1 -1.2 -1.0 -0.6 -1.2 -0.9 -1.5 0.0 -1.0 -1.1
Basal metabolic rate 0.0 0.2 1.1 -0.4 -0.2 0.3 -0.4 -0.5 -0.5 -1.1 0.6 -0.4 -0.3 -0.4 0.5 0.1 0.2 -0.5 0.5 0.5 -0.3 -0.4 -0.5 -0.4 0.0 -0.4 -0.5 -0.7 -0.1 0.1 -0.1 -0.4 -0.5 -0.2 -0.4 -0.4 -0.3 0.1 -0.6 0.1
Leg fat percentage (left) 0.1 0.5 2.6 -1.1 -1.0 -1.3 -0.7 -0.7 -0.6 -1.6 -0.1 -0.9 -0.7 -0.7 0.9 0.2 0.8 -0.6 0.7 0.6 0.0 -0.4 -0.7 -0.9 -0.4 -0.4 -0.6 -0.6 -0.0 -0.6 -0.5 -0.6 -0.5 -0.1 -0.6 -0.5 -0.8 0.2 -0.6 -0.2
Arm fat-free mass (left) 0.0 0.1 0.8 -0.1 -0.1 0.5 -0.1 -0.2 -0.1 -0.9 0.8 -0.4 0.1 -0.1 0.6 -0.3 -0.1 -0.1 0.2 0.1 -0.1 -0.1 -0.2 -0.1 0.3 -0.1 -0.2 -0.3 0.2 0.3 0.2 -0.0 -0.1 0.1 -0.1 -0.1 0.0 0.3 -0.2 0.3
Number of operations (self-reported) 0.4 0.5 1.3 0.7 0.6 0.7 0.6 0.7 0.8 0.4 0.6 0.4 0.6 0.6 1.1 -0.7 -0.3 0.7 -0.6 -0.7 1.1 0.7 0.7 0.7 0.8 0.7 0.7 0.5 0.7 0.9 0.8 0.7 0.7 0.7 0.6 0.7 0.8 0.8 0.7 1.1
Average weekly beer plus cider intake 0.1 0.1 1.2 -0.2 0.5 -0.1 0.1 0.1 -0.3 0.8 0.3 1.1 0.4 0.1 0.2 -0.2 0.1 0.1 -0.0 0.1 0.1 0.2 0.1 0.0 0.3 0.3 0.1 0.5 0.3 -0.3 -0.1 0.1 -0.1 0.2 0.1 0.1 -0.0 0.7 -0.0 -0.2
Irritability 0.7 1.2 2.8 -1.2 -1.1 -1.2 -1.1 -1.2 -1.2 -0.0 -1.2 -1.2 -0.8 -1.2 -0.6 1.3 1.3 -1.1 0.9 1.2 -1.0 -1.1 -0.8 -0.9 -1.0 -1.0 -1.1 -0.8 -0.8 -1.7 -1.2 -1.1 -1.1 -1.3 -1.2 -1.1 -1.1 -1.2 -1.0 -1.5
Risk taking 1.9 2.7 10.1 2.6 0.9 1.9 1.6 1.6 1.7 0.6 1.9 -0.9 1.5 1.5 0.3 -1.7 -1.5 1.6 -1.2 -1.7 1.3 1.2 1.0 1.6 1.3 1.1 1.6 0.7 1.5 3.2 2.4 1.6 1.7 1.5 1.7 1.5 2.3 0.9 1.2 3.0
Ever had prostate specific antigen (PSA) test 0.8 0.9 1.8 0.9 0.9 0.6 1.3 0.9 1.3 1.1 0.5 0.7 1.1 1.0 0.7 -0.9 -1.1 1.0 -1.2 -1.1 0.6 0.9 0.9 1.0 0.7 1.0 1.0 0.9 0.4 0.7 0.8 1.0 1.1 0.9 0.9 1.0 0.9 0.4 1.2 1.0
Fractured/broken bones in last 5 years 1.5 2.0 4.6 1.2 0.7 1.5 1.2 1.3 1.5 -0.3 1.4 1.2 1.3 1.3 1.3 -1.7 -1.4 1.3 -1.1 -1.4 1.7 1.5 1.7 1.4 1.8 1.5 1.3 1.2 1.1 1.5 1.7 1.3 1.4 1.6 1.4 1.4 1.1 2.1 1.3 1.6
Age started oral contraceptive pill 1.6 2.1 4.0 2.0 1.3 1.7 1.4 1.5 1.5 1.4 1.0 0.5 1.5 1.5 -0.2 -1.5 -1.1 1.6 -1.3 -1.5 1.3 1.3 1.8 2.0 1.4 1.2 1.5 1.2 1.2 1.7 1.8 1.5 1.5 1.0 1.6 1.4 1.8 0.8 1.4 1.5
Diastolic blood pressure, automated reading 0.2 0.5 1.3 -0.6 -0.9 0.5 -0.5 -0.7 -0.7 -1.2 -0.1 -0.8 -0.8 -0.6 0.4 0.5 -0.0 -0.7 0.9 0.7 -0.8 -0.6 -1.0 -1.0 -0.7 -0.7 -0.7 -1.0 -0.5 -0.2 -0.7 -0.9 -0.8 -0.3 -0.7 -0.7 -0.6 -0.5 -0.9 -0.4
Ever depressed for a whole week 2.5 3.1 5.9 1.8 1.7 2.2 1.8 1.8 1.8 1.1 2.4 0.9 1.5 1.8 1.7 -2.1 -1.8 1.8 -1.7 -1.8 1.8 1.8 1.4 1.7 1.9 1.7 1.8 1.5 1.7 1.9 1.8 1.6 1.8 1.9 1.8 1.7 1.9 1.6 1.7 1.9
Unable to work because of sickness or disability 0.0 0.1 0.6 0.3 -0.2 -0.1 -0.0 0.0 -0.1 -0.4 0.0 -0.8 0.0 0.1 -0.1 0.1 -0.2 0.1 0.1 0.0 -0.2 -0.1 0.0 0.0 -0.2 -0.2 0.0 -0.2 0.2 0.6 0.4 0.0 -0.0 0.0 0.0 -0.0 0.1 -0.0 -0.1 0.5
Commuting to job workplace: Cycle 1.1 1.4 2.9 0.9 1.3 0.6 0.8 1.3 0.9 1.5 0.8 1.4 1.3 1.2 0.8 -1.3 -0.8 1.2 -1.0 -1.1 1.6 1.3 1.3 1.2 1.5 1.3 1.2 1.3 1.7 0.6 0.9 1.2 1.1 1.2 1.3 1.2 1.1 1.6 1.1 0.4
Myopia 4.0 5.7 8.5 -2.7 -2.9 -2.5 -2.6 -2.5 -2.5 -2.2 -1.9 -1.8 -2.6 -2.4 -2.0 2.5 2.5 -2.5 2.3 2.5 -2.3 -2.4 -2.2 -2.3 -2.1 -2.2 -2.5 -2.2 -2.0 -2.7 -2.6 -2.4 -2.5 -2.5 -2.6 -2.5 -2.6 -2.1 -2.4 -2.5
Vascular/heart problems diagnosed by doctor 0.2 0.6 6.9 -0.3 -0.0 -2.0 -0.3 -0.3 -0.4 1.2 -1.5 -0.3 -0.3 -0.5 -2.6 0.6 0.9 -0.4 0.5 0.3 -0.3 -0.5 -0.4 -0.3 -0.6 -0.5 -0.3 -0.4 -0.3 -0.4 -0.2 -0.3 -0.4 -0.5 -0.4 -0.4 -0.2 -0.6 -0.4 -0.5
Cholesterol lowering medication 1.3 1.9 7.5 -1.3 -1.7 -0.9 -1.3 -1.4 -1.3 -2.7 -1.2 -1.7 -1.8 -1.3 0.2 1.2 1.4 -1.4 1.4 1.4 -0.8 -1.4 -1.4 -1.4 -1.0 -1.4 -1.4 -1.9 -1.2 -0.7 -1.3 -1.5 -1.5 -1.3 -1.4 -1.4 -1.3 -0.7 -1.6 -0.9
Medication: Omeprazole (e.g. Zanprol) 0.2 0.3 0.9 0.7 0.8 0.2 0.6 0.5 0.6 -0.1 0.6 0.1 0.4 0.6 0.0 -0.3 -0.5 0.6 -0.8 -0.6 0.3 0.4 0.6 0.5 0.1 0.3 0.6 0.3 0.1 0.8 0.6 0.6 0.6 0.5 0.5 0.5 0.6 0.2 0.5 1.0
Pain experienced in last month 1.8 3.1 5.5 -1.4 -2.2 -1.2 -1.7 -1.7 -1.7 -1.3 -1.8 -2.3 -1.4 -1.9 -1.6 1.7 1.6 -1.8 1.8 1.7 -1.9 -1.9 -1.9 -1.7 -1.9 -1.8 -1.8 -1.7 -1.6 -1.7 -1.8 -1.6 -1.7 -1.9 -1.7 -1.8 -1.5 -2.0 -1.7 -2.0
Supplements: Calcium 3.7 4.1 7.1 1.5 2.2 2.7 1.7 2.0 2.2 1.1 2.4 2.6 1.8 1.9 2.4 -2.2 -2.2 1.9 -1.8 -2.1 2.2 2.2 2.5 2.2 2.4 2.1 1.9 2.1 1.7 1.2 1.9 1.9 2.0 1.9 1.9 2.1 1.6 2.1 2.2 1.0
Basal cell carcinoma (self-reported) 1.7 2.0 4.5 1.9 1.3 1.5 1.3 1.5 1.6 -0.4 1.3 0.2 1.2 1.3 1.4 -1.5 -1.5 1.4 -1.2 -1.6 1.2 1.3 1.4 1.6 1.4 1.2 1.4 0.6 1.1 2.1 2.0 1.3 1.4 1.3 1.5 1.4 1.7 1.1 1.2 2.0
Heart attack/myocardial infarction (self-reported) 0.2 0.3 2.2 0.3 -0.6 -0.2 -0.3 -0.2 -0.2 0.5 -0.6 -1.5 -0.3 -0.1 -1.1 0.7 0.6 -0.2 0.4 0.2 -0.2 -0.6 -0.9 -0.5 -0.8 -0.6 -0.3 -0.8 -0.4 0.5 -0.5 -0.3 -0.2 -0.5 -0.2 -0.4 0.0 -0.9 -0.4 0.4
Deep venous thrombosis (DVT) (self-reported) 0.3 0.4 2.5 0.3 -0.3 -0.1 -0.4 -0.4 -0.4 0.1 -0.4 -1.6 -0.2 -0.1 -1.6 0.5 0.3 -0.4 0.4 0.4 -0.7 -0.7 -0.8 -0.5 -0.9 -0.8 -0.3 -0.6 -0.1 0.5 -0.5 -0.4 -0.4 -0.6 -0.4 -0.5 0.0 -1.1 -0.5 0.1
Heart disease (siblings) 0.3 0.3 2.7 0.6 -0.3 1.6 0.3 0.3 0.2 -1.6 0.5 -0.7 0.4 0.6 0.7 -0.5 -0.5 0.3 0.1 -0.3 0.4 0.2 0.1 0.3 0.5 0.1 0.2 -0.1 0.5 1.1 0.3 0.3 0.2 0.3 0.3 0.2 0.5 0.3 0.1 0.4
Alcohol drinker status: Previous 2.3 2.6 4.2 1.6 1.3 1.9 1.9 1.7 1.4 0.8 2.0 0.7 1.8 1.9 1.3 -1.8 -1.6 1.8 -1.4 -1.6 1.4 1.6 1.5 1.7 1.7 1.6 1.7 1.4 1.6 1.9 1.7 1.7 1.6 1.6 1.7 1.6 1.8 1.3 1.5 1.6
Pack years of smoking 0.0 0.1 0.7 -0.1 -0.3 0.0 -0.3 -0.0 -0.4 -0.9 0.2 -0.7 0.0 -0.1 0.3 0.2 0.0 -0.0 0.2 0.2 -0.3 -0.2 0.0 -0.1 -0.2 -0.2 -0.1 -0.2 0.0 0.1 0.1 0.0 -0.2 -0.1 -0.1 -0.1 -0.1 -0.1 -0.3 -0.0
Impedance of whole body 0.2 1.2 2.1 1.1 1.0 1.2 1.4 1.3 1.2 0.3 0.4 0.5 1.1 1.3 0.1 -0.8 -1.1 1.3 -1.2 -1.2 1.2 1.2 1.2 1.2 0.8 1.2 1.3 1.5 1.1 0.6 0.9 1.3 1.3 1.1 1.3 1.3 1.2 0.8 1.4 0.8
Leg fat mass (left) 0.2 0.8 3.0 -1.1 -1.1 -1.1 -1.0 -0.9 -0.9 -1.7 -0.1 -1.1 -0.9 -0.9 0.5 0.6 0.9 -0.9 0.9 0.9 -0.4 -0.8 -1.1 -1.2 -0.7 -0.7 -0.9 -1.0 -0.4 -0.5 -0.8 -0.9 -0.9 -0.4 -0.9 -0.8 -1.0 -0.3 -1.0 -0.3
Arm predicted mass (left) 0.0 0.1 0.7 -0.3 -0.2 0.4 -0.2 -0.3 -0.2 -0.8 0.7 -0.3 -0.1 -0.2 0.7 -0.2 -0.0 -0.3 0.3 0.2 -0.1 -0.2 -0.3 -0.2 0.3 -0.1 -0.3 -0.5 0.1 0.3 0.1 -0.2 -0.2 0.0 -0.2 -0.2 -0.2 0.4 -0.3 0.3