Hub : Genes

NT5E

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1850	0.0460	3.5e-11	0.105	0.101	0.087	0.112	0.121	1.0e-12	3.0e-12	9.3e-11	1.7e-13	1.6e-14
2	GTEx	Cells EBV-transformed lymphocytes	0.4360	0.1400	1.9e-03	0.037	NA	-0.008	NA	0.013	2.3e-02	NA	8.1e-01	NA	1.2e-01
3	GTEx	Liver	0.2580	0.1090	4.7e-03	0.289	NA	0.201	NA	0.282	1.0e-08	NA	2.7e-06	NA	1.6e-08
4	GTEx	Nerve Tibial	0.0741	0.0286	1.2e-04	0.033	NA	0.037	NA	0.032	2.0e-03	NA	1.2e-03	NA	2.3e-03
5	GTEx	Testis	0.1730	0.0640	1.3e-03	0.062	NA	0.002	NA	0.052	1.0e-03	NA	2.6e-01	NA	2.5e-03
6	GTEx	Thyroid	0.3680	0.0550	0.0e+00	0.389	NA	0.388	NA	0.390	2.0e-31	NA	2.2e-31	NA	1.5e-31
7	GTEx	Whole Blood	0.1150	0.0380	2.7e-05	0.049	NA	0.042	NA	0.036	2.5e-05	NA	8.7e-05	NA	2.7e-04
8	ROSMAP	Brain Pre-frontal Cortex	0.2413	0.0459	0.0e+00	0.170	0.166	0.206	0.201	0.209	2.8e-21	8.6e-21	5.6e-26	2.6e-25	2.3e-26
9	YFS	Blood	0.2494	0.0357	0.0e+00	0.239	0.269	0.271	0.268	0.269	3.8e-77	6.4e-88	8.8e-89	8.9e-88	4.5e-88
10	TCGA	Breast Invasive Carcinoma	0.0129	0.0075	2.2e-03	0.004	0.006	0.003	NA	0.005	4.1e-02	1.8e-02	5.8e-02	NA	2.9e-02
11	TCGA	Rectum Adenocarcinoma	0.2250	0.1200	7.9e-03	0.173	0.055	0.054	NA	0.123	7.3e-05	2.0e-02	2.2e-02	NA	8.3e-04
12	TCGA	Thyroid Carcinoma	0.0710	0.0330	1.4e-06	0.033	0.036	0.041	NA	0.025	3.1e-04	1.8e-04	6.7e-05	NA	1.6e-03

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12
Bipolar Disorder (2018)	0.7	1.0	3.1	0.5	-1.8	-1.8	-1.5	-1.2	0.1	-0.2	0.3	-0.6	0.1	1.3	0.2
Bipolar Disorder or Schizophrenia	1.0	2.5	13.2	-0.3	-0.2	-1.2	-3.6	-0.3	-0.8	0.5	-0.5	-0.4	-1.1	3.5	-0.5
Depressed Affect (Nagel 2018)	0.3	0.7	3.2	0.6	0.6	-0.1	1.3	-0.2	0.9	-0.2	0.7	-0.1	1.1	-1.8	0.7
Depression (Nagel 2018)	1.1	1.6	2.5	1.4	0.4	-1.6	-0.2	-1.5	1.4	-1.1	1.4	-1.5	1.5	-0.5	1.5
Intelligence (Savage-Jansen 2018)	1.3	4.0	6.5	2.2	-1.3	-2.5	-2.2	-2.6	1.5	-1.9	2.0	-2.5	1.3	1.9	1.5
Neuroticism (Nagel 2018)	0.4	0.9	3.1	1.4	-1.2	0.0	-0.4	-0.4	1.0	-0.6	1.8	-0.6	1.0	-0.1	0.8
Schizophrenia (2018)	1.3	2.7	12.0	-0.7	1.5	-0.1	-3.5	0.5	-1.1	0.8	-0.9	-0.1	-1.5	3.5	-0.8
Schizophrenia vs Biploar Disorder	0.4	0.5	2.5	-0.5	1.6	0.7	-0.6	0.9	-0.3	0.1	-0.4	0.1	-0.4	0.9	-0.4
Worry (Nagel 2018)	0.7	1.5	3.5	1.6	-1.8	-1.2	-0.5	-1.0	1.1	-0.9	1.9	-1.2	1.1	0.2	0.9
Alzheimer’s Disease (in mother)	2.4	2.8	6.6	1.4	-0.7	-2.1	-0.0	-1.9	1.8	-1.9	0.7	-2.2	2.0	-0.2	2.6
Alzheimer’s Disease (in father)	0.9	0.9	6.1	0.7	-2.5	-0.8	-0.3	-0.8	0.6	-0.5	0.9	-0.8	0.4	0.9	0.6
Alzheimer’s Disease (including proxy)	2.5	3.6	7.4	1.5	-2.1	-2.3	0.8	-2.0	2.1	-2.1	0.9	-2.2	2.2	-0.4	2.7
Crohns Disease (2017)	0.5	1.0	3.2	-0.8	-0.1	0.2	-1.4	0.4	-1.1	0.9	-0.9	0.5	-1.3	1.8	-1.0
Irritable Bowel Disease (IBD)	0.3	0.7	3.6	0.2	-0.4	0.1	-1.8	-0.3	-0.3	-0.1	0.1	-0.6	-0.5	1.9	-0.3
Ulcerative Colitis (UC)	0.3	0.6	2.6	0.5	-0.1	-0.0	-1.6	-0.4	0.1	-0.5	0.5	-0.9	-0.1	1.6	-0.1
Major Depression (MDD)	0.6	0.7	3.1	-0.0	1.8	-1.2	-1.2	-0.2	-0.2	0.5	-0.5	-0.4	-0.5	1.4	-0.1
Reaction Time	0.2	0.3	1.3	-0.0	1.0	-0.9	-0.4	-0.1	-0.4	-0.1	-0.0	-0.1	-0.4	1.1	-0.3
Verbal and Numeric Reasoning (VNR)	0.2	0.6	2.2	0.6	0.1	-1.5	-1.2	-0.9	0.1	-0.2	0.4	-0.7	0.0	1.1	-0.1
Breast Cancer	0.1	0.2	0.6	-0.2	-0.8	0.1	0.2	0.5	-0.0	0.2	-0.7	0.2	0.3	-0.4	0.6
Ovarian Cancer	1.0	1.3	4.0	1.4	-2.0	-1.3	-0.5	-1.3	1.1	-0.7	1.3	-1.0	0.7	0.4	0.6
Prostate Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Age at First Birth	0.6	0.9	4.5	0.7	0.0	-0.8	-2.1	-0.8	0.2	-0.7	0.6	-0.7	-0.1	1.8	0.3
Bipolar Disorder (2011)	0.1	0.1	0.4	0.1	0.3	-0.3	0.2	-0.6	0.2	-0.2	0.0	-0.2	0.3	0.0	0.3
Body Mass Index (BMI) (2010)	1.3	1.8	4.2	-1.6	0.9	0.8	2.1	0.9	-1.2	1.1	-1.6	1.7	-0.7	-1.8	-1.1
Coronary Artery Disease (CAD)	0.4	0.5	1.4	0.8	-1.0	-0.6	0.0	-0.8	0.5	-0.7	1.2	-0.8	0.6	0.5	0.7
Crohns Disease (2012)	0.7	1.1	2.3	-1.2	-0.0	1.2	-0.1	1.1	-1.2	1.0	-1.0	1.1	-1.4	0.8	-1.5
Mean Putamen Volume	1.2	1.4	7.6	0.3	-1.0	0.4	-2.8	0.4	-0.6	0.7	0.5	-0.5	-1.0	2.3	-0.7
Fasting Glucose	2.5	3.0	8.0	1.1	-1.3	-1.0	2.2	-2.1	1.9	-1.6	1.1	-1.1	2.1	-2.8	1.3
HbA1C	2.4	2.6	4.6	1.0	-1.6	-1.7	1.1	-1.8	2.1	-1.8	0.7	-2.0	2.1	-0.8	1.9
HDL Cholesterol	0.1	0.2	0.6	-0.1	0.3	-0.2	-0.6	0.5	-0.5	0.6	-0.4	0.2	-0.5	0.8	-0.5
LDL Cholesterol	0.2	0.3	0.6	0.6	0.5	-0.5	0.1	-0.6	0.6	-0.5	0.8	-0.2	0.5	-0.4	0.4
Lupus	1.1	1.7	3.8	1.2	-0.3	-0.8	1.5	-1.0	1.5	-1.2	0.7	-1.0	1.8	-2.0	1.8
Neuroticism (2016)	0.3	0.5	1.0	-0.8	-0.4	0.6	-0.2	0.8	-0.7	0.8	-0.7	0.6	-0.8	1.0	-0.9
Primary Biliary Cirrhosis	0.3	0.4	1.2	-0.5	-1.1	-0.2	-0.7	0.2	-0.9	0.9	-0.7	0.6	-0.5	0.4	-0.5
Rheumatoid Arthritis	0.4	0.6	2.5	-0.2	0.3	1.6	-0.5	1.3	-0.4	0.8	-0.1	0.8	-0.7	-0.0	-0.9
Schizophrenia (2014)	0.9	1.9	10.6	-0.1	1.5	-0.3	-3.3	-0.3	-0.5	-0.1	-0.1	-0.6	-0.7	3.0	-0.1
Triglycerides	0.5	0.8	1.6	0.9	-0.6	-0.3	0.5	-0.8	1.1	-1.3	1.1	-0.8	1.1	-1.0	0.9
Type 2 Diabetes (T2D) (2012)	0.6	0.7	2.4	-1.4	0.3	-0.5	1.4	0.0	-0.9	0.4	-1.6	0.6	-0.6	-0.5	-0.5
Ulcerative Colitis	0.8	1.2	3.9	0.9	-0.5	-0.5	-2.0	-1.2	1.0	-1.0	0.8	-1.5	0.7	1.3	0.9
Blood Eosinophil Count	0.1	0.4	2.3	-0.7	-0.5	0.6	1.5	0.5	-0.3	0.1	-0.7	0.6	-0.2	-0.6	-0.3
Blood Platelet Count	0.1	0.7	2.2	-0.7	0.0	1.3	0.9	1.5	-0.6	0.8	-0.7	0.7	-0.6	-0.3	-0.9
Blood Red Count	0.1	0.6	3.1	-0.0	0.1	0.1	1.8	0.7	-0.3	0.5	-0.4	0.7	0.0	-1.7	-0.1
Blood White Count	1.1	8.0	33.4	-2.5	-1.9	0.8	5.8	1.5	-1.2	1.8	-2.0	3.2	-0.3	-5.5	-1.1
Heel T-Score	0.7	5.5	14.7	2.6	0.4	1.7	-2.9	-1.1	2.7	-3.2	3.8	-2.6	1.5	1.7	1.4
BMI	0.7	4.1	11.0	-1.9	0.6	2.0	3.3	2.3	-1.6	2.1	-1.5	2.6	-0.9	-2.5	-1.4
Height	0.2	4.2	12.9	-0.2	-2.8	-2.4	1.9	-3.2	1.2	-1.1	-0.2	-1.0	1.9	-3.6	1.7
Waist Hip Ratio (WHR)	0.9	4.1	14.4	-0.7	3.6	1.0	-3.2	1.2	-1.4	1.0	-0.3	0.2	-1.9	3.8	-1.2
Systolic Blood Pressure	0.7	3.7	5.4	-2.2	2.3	1.8	2.0	2.0	-2.0	1.7	-1.8	2.1	-1.7	-1.0	-2.1
Smoking Status	0.2	0.4	2.2	0.6	-1.5	-0.1	0.1	-0.4	0.7	-0.2	1.2	-0.3	0.3	0.4	0.1
Allergy or Eczema	0.5	1.3	4.4	0.4	-1.4	-0.0	1.5	-0.3	1.1	-0.9	0.1	-0.6	1.5	-2.1	1.6
Cardiovascular Disease	0.8	2.7	12.8	0.2	-0.3	-0.6	3.6	-1.2	1.1	-1.3	0.4	-0.2	1.5	-3.4	0.9
Hypothyroidism (self reported)	0.2	0.4	1.6	0.6	-1.1	-1.3	-0.4	-0.5	0.4	-0.2	0.2	-0.4	0.3	0.5	0.4
Respiratory disease	0.3	0.6	1.3	-0.7	0.5	0.4	-0.2	0.9	-1.1	0.8	-0.3	0.8	-0.9	0.9	-0.9
Type 2 Diabetes (T2D) (2018)	0.8	1.5	4.7	0.4	-0.4	-1.0	2.2	-1.3	1.1	-1.4	0.4	-0.9	1.6	-1.7	1.2
Lung FEV1/FVC ratio	0.2	0.8	1.8	0.6	0.8	-1.4	0.9	-1.1	0.7	-0.4	0.2	-0.3	0.9	-1.3	1.2
Lung FVC	0.1	0.5	0.9	-0.8	-0.1	-0.1	-0.1	0.4	-0.9	0.9	-0.9	0.9	-0.9	-0.2	-0.8
Neuroticism	0.2	0.6	1.5	0.8	-0.9	-0.8	0.8	-0.7	0.7	-0.4	1.0	-0.2	0.9	-1.2	0.3
Chronotype (morning person)	0.4	0.8	2.6	0.7	-0.8	-0.1	1.6	-0.4	1.0	-1.0	0.6	-0.7	1.1	-0.8	1.0
Hair Pigment	0.0	0.3	1.3	0.2	0.1	0.5	1.1	-0.2	0.5	-0.3	0.4	-0.1	0.5	-1.1	0.2
Tanning	0.0	0.6	2.3	-0.6	-0.6	0.1	1.5	0.6	-0.5	0.5	-0.7	0.8	-0.5	-0.8	-0.9
Hand grip strength (left)	0.7	1.8	3.4	-1.3	-1.4	1.7	0.1	1.4	-1.4	1.8	-1.0	1.8	-1.4	-0.0	-1.3
Number of treatments/medications taken	0.2	0.3	0.7	0.5	-0.8	0.0	0.2	0.1	0.2	-0.5	0.7	-0.8	0.0	0.8	-0.4
Average weekly spirits intake	0.5	0.7	3.0	-0.1	-1.1	0.5	1.7	0.2	0.6	-0.2	-0.4	0.2	0.8	-1.5	0.5
Sensitivity / hurt feelings	0.2	0.3	0.9	0.0	-0.2	0.9	-0.5	0.9	-0.3	0.2	0.4	0.5	-0.5	0.4	-0.8
Frequency of depressed mood in last 2 weeks	0.4	0.5	2.4	0.8	0.0	-1.5	-0.7	-0.8	0.6	-0.2	0.9	-0.8	0.2	0.2	0.0
Hearing difficulty/problems: Yes	1.0	1.5	3.5	-1.4	1.9	1.1	1.4	1.1	-0.9	1.0	-1.1	1.2	-1.1	-0.2	-1.7
Relative age of first facial hair	2.9	6.1	9.7	3.1	-2.8	-1.5	-0.1	-2.0	3.0	-2.5	3.0	-2.5	2.9	-0.6	3.1
Other serious medical condition/disability diagnosed by doctor	1.2	1.6	3.3	-1.4	0.2	1.8	0.4	1.8	-1.1	1.0	-1.4	1.5	-1.2	-0.0	-1.4
Ever used hormone-replacement therapy (HRT)	0.4	0.5	1.0	0.5	-0.0	-0.8	-0.6	-1.0	0.7	-0.9	0.4	-0.9	0.4	0.8	0.4
Ever had hysterectomy (womb removed)	0.7	0.8	2.1	0.8	-0.7	0.3	-1.1	-0.6	0.9	-0.8	0.7	-1.2	0.7	1.4	0.9
Systolic blood pressure, automated reading	0.5	1.3	2.8	-1.3	1.2	1.7	0.9	1.4	-0.9	1.0	-1.1	1.4	-0.8	-0.8	-0.9
Eye problems/disorders: Diabetes related eye disease	1.1	1.2	2.8	-1.6	0.5	0.9	0.5	1.0	-1.1	1.1	-1.7	1.6	-0.9	-0.5	-0.7
Angina	0.7	0.9	2.6	1.2	-1.6	0.2	-0.3	-0.2	1.0	-0.7	1.3	-0.8	1.1	-0.5	1.2
Medication for hormone replacement therapy	0.8	0.9	2.0	1.0	-0.8	-1.0	-1.4	-0.9	0.4	-1.1	1.4	-0.8	0.2	1.0	0.7
Vitamin and mineral supplements	0.4	0.6	2.3	0.5	0.0	1.5	0.7	-0.0	0.3	-0.6	1.4	0.3	0.5	-0.8	0.6
Supplements: Zinc	0.3	0.3	2.0	0.6	0.0	-0.6	-1.4	-0.3	0.1	-0.3	0.5	-0.5	-0.2	0.7	0.0
Medication: Co-codamol	0.8	0.9	5.6	-0.0	-0.1	-0.6	1.7	0.0	0.6	-0.4	-0.4	-0.1	0.9	-2.4	0.7
Medication: Metformin	0.1	0.2	1.8	-0.4	0.0	-0.1	1.3	0.0	0.1	-0.2	-0.1	0.1	0.2	-0.4	-0.3
Diabetes (father)	0.7	0.9	1.6	0.9	0.9	-0.4	-0.9	-1.1	1.2	-0.9	0.9	-1.1	1.0	-0.2	1.2
Diabetes (mother)	1.6	2.0	3.5	-1.4	0.6	1.2	0.1	1.7	-1.9	1.7	-0.8	1.7	-1.8	1.1	-1.8
Severe depression (siblings)	1.0	1.2	3.6	1.0	-1.9	-1.3	-0.0	-1.2	1.3	-0.8	0.5	-0.7	1.1	-1.0	1.1
Pack years adult smoking proportion	0.4	0.6	1.1	-0.8	0.8	-0.3	1.0	0.1	-0.7	0.9	-0.8	1.0	-0.4	-1.0	-0.5
Impedance of leg (right)	0.5	2.2	11.9	0.9	0.8	-0.9	-3.5	-0.6	0.1	-0.4	0.2	-1.2	-0.6	3.2	0.3
Leg fat-free mass (left)	0.7	3.5	17.1	-1.6	0.1	0.0	4.1	0.1	-0.8	0.9	-0.9	1.8	0.1	-4.0	-0.8
Trunk fat percentage	0.8	3.1	8.2	-1.7	1.0	0.9	2.9	1.4	-1.2	1.9	-1.7	2.1	-0.6	-2.8	-1.1
Hand grip strength (right)	0.8	2.2	4.5	-1.5	-0.5	1.6	-0.8	1.4	-1.7	2.1	-1.1	1.9	-1.8	0.9	-1.5
Townsend deprivation index at recruitment	0.8	1.1	3.8	-0.1	1.5	0.7	-2.0	0.6	-0.7	0.4	0.2	0.2	-1.1	1.7	-0.9
Current tobacco smoking	0.8	1.3	5.7	0.9	-2.4	-0.8	1.3	-0.7	0.9	-0.8	1.3	-0.5	1.0	-1.1	0.7
Average weekly fortified wine intake	0.5	0.6	2.1	0.6	-1.4	-0.6	0.1	-1.0	0.8	-1.2	0.4	-0.9	0.4	-0.1	0.3
Maternal smoking around birth	0.2	0.3	0.8	0.2	-0.1	-0.1	-0.5	-0.8	0.7	-0.5	-0.0	-0.5	0.7	-0.3	0.9
Fed-up feelings	0.1	0.2	0.6	0.4	0.6	-0.4	0.1	-0.4	0.6	-0.5	0.5	-0.1	0.6	-0.8	0.4
Frequency of unenthusiasm / disinterest in last 2 weeks	1.3	1.8	6.2	1.2	1.2	-2.5	0.2	-1.9	1.2	-1.1	1.1	-1.4	1.3	-0.5	1.2
Relative age voice broke	1.1	1.6	5.3	1.5	-2.3	-0.1	1.2	-0.3	1.3	-0.9	1.4	-0.8	1.5	-1.1	1.4
Taking other prescription medications	0.2	0.4	1.0	1.0	-0.4	-0.3	-0.1	-0.3	0.5	-0.9	0.9	-0.8	0.5	0.3	0.2
Age when periods started (menarche)	0.4	0.9	3.3	-1.1	1.2	1.8	0.2	1.2	-0.6	0.6	-0.8	1.0	-0.7	0.0	-0.7
Bilateral oophorectomy (both ovaries removed)	0.4	0.5	1.3	0.6	-1.1	-0.2	-0.7	-0.6	0.4	-0.7	0.7	-0.8	0.4	1.0	0.6
Heel bone mineral density (BMD) T-score, automated (left)	2.1	4.7	10.6	2.7	-0.5	-0.2	-1.2	-1.9	3.0	-2.8	3.3	-2.8	2.2	0.4	1.9
Tinnitus: Yes, but not now, but have in the past	0.4	0.4	1.4	-0.6	-0.8	-0.9	0.1	-0.2	-0.6	0.4	-1.2	0.4	-0.5	0.5	-0.2
Qualifications: CSEs or equivalent	0.3	0.4	2.0	-0.5	1.4	0.4	0.9	0.1	-0.4	0.5	-0.3	0.8	-0.2	-0.8	-0.4
Serious illness, injury or assault to yourself	0.8	1.0	3.2	0.8	-0.1	-1.7	-1.8	-1.1	0.1	-0.7	0.9	-0.5	0.1	1.1	0.8
High blood pressure	0.2	0.6	2.8	0.2	0.3	-0.5	1.7	-0.7	0.4	-1.1	0.5	-0.2	0.7	-1.2	0.5
Hayfever, allergic rhinitis or eczema	0.3	0.6	2.7	0.3	-1.6	-0.1	1.1	-0.1	0.7	-0.3	0.0	-0.4	0.9	-1.2	0.9
Multivitamins +/- minerals	0.5	0.7	1.4	-0.6	0.6	0.0	-1.1	0.7	-0.6	1.2	-1.0	0.1	-0.9	1.1	-1.0
Stomach or abdominal pain in last month	0.4	0.5	1.4	0.9	-0.2	-0.1	-0.3	-0.4	1.1	-0.9	1.1	-1.2	0.4	0.4	0.1
Supplements: Glucosamine	0.2	0.3	1.9	0.4	0.2	-0.3	-1.4	-0.4	0.2	-0.0	0.3	-0.7	-0.0	0.8	-0.0
Diverticular disease/diverticulitis (self-reported)	0.4	0.5	1.3	1.1	-1.1	0.5	0.5	0.1	0.6	-0.9	1.1	-0.6	0.4	-0.1	-0.0
Medication: Atenolol	0.5	0.7	1.6	0.8	-0.5	0.4	1.1	0.2	0.6	-1.1	0.7	-0.5	1.1	-1.3	0.8
Medication: Levothyroxine sodium	0.2	0.3	1.5	-0.4	-1.2	0.2	0.8	0.3	0.0	0.3	-0.6	0.5	0.1	-0.7	-0.0
Sitting height	0.5	3.3	15.8	-1.8	-1.0	-1.5	3.0	-1.0	-0.8	1.2	-1.7	1.5	0.1	-4.0	-0.1
Chronic bronchitis/emphysema (father)	1.6	1.9	5.1	2.2	-1.5	0.1	-0.9	-0.2	1.4	-1.4	2.3	-1.4	1.4	0.4	1.3
High blood pressure (mother)	0.4	0.6	1.7	-1.1	0.7	-0.2	0.2	0.1	-1.0	0.7	-1.3	0.6	-0.9	0.2	-0.6
Body mass index (BMI)	0.7	3.2	11.5	-1.4	0.8	1.7	3.4	1.6	-1.0	1.5	-0.9	2.0	-0.4	-3.0	-1.1
Impedance of leg (left)	0.4	2.1	11.4	1.0	0.5	-1.1	-3.4	-0.9	0.4	-0.5	0.3	-1.3	-0.2	2.7	0.8
Leg predicted mass (left)	0.7	3.6	17.8	-1.6	0.1	0.0	4.2	0.2	-0.8	1.0	-0.9	1.9	0.1	-4.1	-0.8
Trunk fat mass	0.7	3.2	11.0	-1.6	0.7	0.7	3.3	1.1	-1.1	1.7	-1.4	2.1	-0.4	-3.3	-0.9
Waist circumference	0.7	2.5	3.8	-1.5	1.9	1.5	1.9	1.7	-1.4	1.8	-1.0	1.9	-1.0	-1.5	-1.5
Number of incorrect matches in round	0.4	0.7	2.4	0.6	-0.2	-0.8	-1.3	-0.2	0.4	-1.0	0.5	-0.7	0.3	1.6	0.8
Past tobacco smoking	0.3	0.6	1.2	0.5	-0.0	-0.8	0.4	-0.9	0.7	-1.0	0.2	-0.5	1.0	-0.9	1.1
Alcohol usually taken with meals	1.3	2.1	5.2	1.9	-2.3	-0.6	-0.6	-1.2	1.5	-1.3	1.9	-1.3	1.5	-0.2	1.5
Nervous feelings	0.2	0.3	1.8	0.5	-1.3	-0.0	-0.9	0.1	-0.1	0.3	0.5	0.0	-0.3	0.3	-0.4
Frequency of tenseness / restlessness in last 2 weeks	1.0	1.6	4.9	1.3	-0.7	-2.2	-0.8	-1.8	1.0	-1.2	1.4	-1.3	0.9	0.3	1.1
Hearing difficulty/problems with background noise	0.6	0.9	5.0	-0.7	-0.0	1.0	2.2	0.5	0.1	0.2	-0.4	0.9	0.1	-1.7	-0.6
Hair/balding pattern: Pattern 2	1.3	1.7	3.8	1.7	0.1	-1.2	-0.4	-1.6	1.4	-1.6	1.9	-1.6	1.1	0.1	1.0
Had menopause	0.1	0.1	0.2	0.2	-0.5	-0.1	0.4	-0.0	0.3	-0.3	-0.1	-0.2	0.4	-0.4	0.4
Had other major operations	1.5	1.8	3.0	1.3	-0.9	-1.0	-1.4	-1.7	1.7	-1.6	1.1	-1.6	1.2	0.5	1.6
Forced vital capacity (FVC)	0.2	0.7	1.7	-1.2	-0.4	-1.0	0.3	-0.5	-0.9	0.8	-1.3	1.1	-0.9	-0.9	-0.4
Heel bone mineral density (BMD) T-score, automated (right)	1.6	3.6	9.9	2.4	-0.5	0.9	-1.9	-1.0	2.1	-2.4	3.1	-2.4	1.3	1.8	1.1
Ever unenthusiastic/disinterested for a whole week	1.5	1.8	4.0	-1.4	2.0	0.4	0.1	1.1	-1.5	1.7	-1.8	1.4	-1.4	0.3	-1.4
Qualifications: None of the above	1.7	3.7	7.5	1.4	-2.0	-1.1	1.5	-1.6	2.4	-2.3	1.2	-1.8	2.7	-1.7	2.5
Financial difficulties in last 2 years	0.2	0.3	1.3	0.0	0.3	-1.1	0.9	-0.2	-0.3	0.2	-0.2	0.2	-0.1	-0.9	0.1
Mouth/teeth dental problems	0.1	0.2	0.9	-0.5	0.3	1.0	-0.1	0.6	-0.1	0.2	-0.3	0.1	-0.5	0.4	-0.8
Heart attack	2.4	3.0	5.0	2.1	-1.3	-1.8	0.2	-2.0	1.9	-1.8	1.9	-2.2	1.9	-0.2	1.8
Allergy	0.1	0.3	1.6	0.2	1.0	-0.1	-1.3	-0.5	0.1	-0.3	0.3	-0.0	-0.1	0.7	0.1
Pain all over the body in last month	0.7	0.8	3.5	-0.7	1.9	0.5	-0.2	0.5	-1.0	0.9	-0.9	1.0	-0.8	-0.1	-0.8
Diabetes (self-reported)	0.5	0.7	2.7	0.3	0.0	-0.6	1.6	-0.7	0.8	-0.7	0.4	-0.4	1.1	-1.5	0.6
Hayfever/allergic rhinitis (self-reported)	0.2	0.2	0.8	-0.1	0.8	-0.4	0.9	0.2	0.3	-0.4	-0.7	-0.4	0.4	-0.1	0.4
Medication: Ramipril	0.2	0.3	0.9	0.4	-0.7	0.6	1.0	0.2	0.5	-0.3	0.9	-0.1	0.6	-0.3	0.2
Medication: Simvastatin	1.7	2.6	7.1	0.8	-2.7	-0.9	2.2	-1.4	1.5	-1.3	0.9	-0.9	1.7	-2.3	1.2
Fluid intelligence score	0.2	0.3	1.2	0.7	-0.1	-0.6	-1.1	-0.1	-0.3	0.1	0.7	-0.1	-0.5	0.8	-0.5
Illnesses of siblings	1.0	1.4	2.8	-1.3	0.8	0.3	-0.5	1.0	-1.7	1.6	-1.4	1.1	-1.5	0.9	-1.4
Neuroticism score	0.4	0.8	1.4	1.2	-1.2	-1.0	-0.1	-0.8	0.9	-0.8	1.2	-0.7	1.0	-0.4	0.7
Weight	0.7	3.3	14.4	-1.5	0.2	0.4	3.8	0.6	-0.9	1.4	-1.0	2.0	-0.1	-3.8	-0.9
Impedance of arm (right)	0.6	2.7	11.2	-0.6	1.6	-1.2	-3.4	-0.3	-1.1	1.0	-1.3	-0.0	-1.7	2.9	-0.8
Arm fat percentage (right)	0.8	3.4	5.2	-1.8	1.8	1.4	2.2	1.8	-1.7	2.2	-1.6	2.3	-1.2	-1.9	-1.6
Trunk fat-free mass	0.5	2.6	14.0	-0.3	-0.8	-0.9	3.5	-1.0	0.2	-0.3	0.2	0.7	1.1	-3.7	0.4
Hip circumference	0.9	3.7	9.4	-1.7	1.0	1.7	2.8	1.6	-1.4	2.1	-1.2	2.5	-0.9	-3.1	-1.6
Time employed in main current job	1.8	2.0	3.4	-1.3	1.2	1.4	-1.3	1.4	-1.4	1.7	-1.1	1.4	-1.8	1.2	-1.6
Alcohol intake versus 10 years previously	0.2	0.3	1.5	0.4	1.2	0.4	-0.7	-0.1	0.1	-0.4	0.7	-0.3	-0.2	0.6	-0.4
Father’s age at death	0.5	0.7	2.1	0.9	1.1	-0.6	-1.4	-0.6	0.6	-0.6	0.7	-1.0	0.3	1.2	0.3
Worrier / anxious feelings	0.9	1.7	3.2	1.5	-1.7	-0.9	-1.5	-1.2	1.3	-1.4	1.8	-1.3	0.9	0.7	0.9
Frequency of tiredness / lethargy in last 2 weeks	1.4	2.3	4.1	2.0	1.3	-2.0	-0.8	-1.7	1.4	-1.3	1.6	-1.7	1.4	-0.1	1.6
Falls in the last year	0.2	0.3	1.7	0.1	0.3	-0.9	0.7	-0.5	0.1	-0.0	-0.1	0.3	0.3	-1.3	0.2
Hair/balding pattern: Pattern 3	2.6	3.8	7.5	-2.2	1.7	-0.0	-0.2	1.5	-2.7	2.5	-2.7	2.0	-2.4	0.6	-2.1
Number of live births	1.0	1.4	5.3	-1.5	-0.2	0.3	0.5	1.2	-1.2	1.5	-2.3	1.4	-1.0	0.1	-0.9
Forced expiratory volume in 1-second (FEV1)	0.2	0.8	2.3	-1.1	-0.0	-0.8	0.9	-0.5	-0.7	0.8	-1.4	1.2	-0.6	-1.5	-0.3
Pulse rate	0.4	0.7	2.0	-0.6	1.4	-0.1	1.2	0.5	-0.9	1.1	-0.4	0.8	-0.7	-0.2	-1.1
Happiness	0.2	0.3	1.4	-0.2	0.4	-0.4	0.9	0.1	0.1	0.2	-0.5	-0.1	-0.0	-1.2	-0.4
Noisy workplace	0.5	0.6	3.0	-0.1	1.7	-1.1	1.5	-0.4	0.1	-0.5	-0.2	-0.5	0.4	-0.3	0.2
Qualifications: A levels/AS levels or equivalent	0.6	1.3	3.2	-0.6	1.3	0.7	-1.8	0.9	-1.0	1.0	-0.4	0.4	-1.4	1.5	-1.4
Serious illness, injury or assault of a close relative in last 2 years	2.4	2.8	5.8	-1.1	-0.2	1.0	-2.0	1.8	-2.0	1.8	-0.9	1.5	-2.4	1.9	-2.0
Mouth/teeth dental problems: Dentures	0.5	0.9	2.2	-0.9	0.4	0.7	1.5	1.1	-0.7	1.1	-0.9	1.1	-0.5	-1.0	-0.8
Asthma	0.5	0.9	2.3	-0.6	-0.5	0.5	-0.9	0.9	-1.2	1.1	-0.4	0.7	-1.3	1.5	-1.1
Medication: Ibuprofen (e.g. Nurofen)	0.3	0.4	1.1	-0.1	1.0	-0.1	0.4	0.7	-1.0	0.6	-0.0	0.9	-0.7	-0.1	-0.6
Medication: Cholesterol lowering	1.3	2.0	8.5	1.1	-2.9	-1.0	0.9	-1.2	1.4	-1.6	1.2	-1.2	1.5	-0.8	1.2
Depression (self-reported)	1.3	1.6	3.1	1.4	-1.5	-0.9	-0.6	-1.4	1.6	-1.2	1.4	-1.8	1.1	0.4	0.9
Medication: Lansoprazole	0.3	0.4	1.3	0.6	1.1	-0.0	-0.3	-0.5	0.7	-0.6	0.9	-0.5	0.5	-0.6	0.4
Prospective memory result	0.3	0.4	1.7	-0.9	0.1	-0.1	0.5	0.7	-0.6	0.8	-1.3	0.8	-0.5	-0.0	-0.4
Lung cancer (father)	2.0	2.4	3.2	1.3	-1.5	-1.3	1.6	-1.7	1.7	-1.6	1.2	-1.4	1.8	-1.5	1.7
Illnesses of mother	0.1	0.2	0.4	0.4	-0.5	0.4	-0.5	0.1	0.2	-0.2	0.6	-0.5	-0.0	0.7	-0.4
Forced expiratory volume in 1-second (FEV1), Best measure	0.4	1.2	2.5	-1.3	-0.3	-0.9	0.9	-0.2	-1.1	1.1	-1.6	1.6	-0.9	-1.6	-0.5
Pulse wave Arterial Stiffness index	0.9	1.0	5.2	-0.8	0.2	0.0	2.3	0.3	-0.1	0.5	-1.2	0.6	0.2	-2.0	-0.0
Impedance of arm (left)	0.4	2.0	12.0	0.1	0.6	-1.3	-3.5	-0.5	-0.4	0.5	-0.7	-0.5	-1.1	2.7	-0.1
Arm fat mass (right)	0.9	3.5	11.1	-1.7	1.2	1.0	3.3	1.4	-1.3	1.9	-1.4	2.3	-0.6	-3.1	-1.2
Trunk predicted mass	0.4	2.4	12.8	-0.3	-0.8	-0.9	3.4	-1.0	0.2	-0.3	0.2	0.6	1.1	-3.6	0.4
Standing height	0.2	2.1	8.4	-0.2	-1.1	-2.9	1.6	-2.3	0.2	-0.3	-0.3	0.1	0.8	-2.5	0.8
Length of working week for main job	1.3	1.4	3.0	-0.8	1.7	0.8	-0.9	1.1	-1.2	0.8	-0.5	0.6	-1.5	1.6	-1.7
Exposure to tobacco smoke at home	0.5	0.5	1.3	-0.1	0.6	0.9	-0.5	1.0	-0.4	0.5	-0.2	0.3	-0.9	1.1	-1.1
Breastfed as a baby	1.2	1.4	3.0	1.4	-0.7	-1.3	-0.2	-1.5	1.2	-1.2	1.6	-1.7	1.2	0.4	0.9
Tense / ‘highly strung’	1.2	2.0	4.3	1.7	-2.1	-1.4	-1.5	-1.1	1.0	-1.1	2.0	-1.4	0.8	1.3	0.9
Seen doctor (GP) for nerves, anxiety, tension or depression	0.1	0.1	0.4	0.3	-0.5	-0.1	0.0	-0.2	0.4	-0.1	0.1	-0.2	0.4	-0.6	0.2
Hair/balding pattern: Pattern 4	2.8	6.8	12.4	-2.8	3.5	2.7	-0.4	3.0	-3.0	2.2	-2.6	2.5	-3.0	1.2	-2.7
Birth weight of first child	0.1	0.1	0.6	-0.3	-0.8	0.1	-0.2	-0.3	0.2	-0.5	-0.3	0.0	0.0	0.4	0.3
Peak expiratory flow (PEF)	0.4	0.9	1.7	-1.0	1.2	-0.3	0.4	0.2	-1.1	1.3	-1.2	1.1	-1.1	-0.4	-0.9
Pulse wave reflection index	0.6	0.7	3.1	-0.6	0.7	0.9	1.8	0.2	0.3	0.1	-0.6	0.2	0.6	-1.6	0.2
Ever highly irritable/argumentative for 2 days	0.5	0.6	3.1	-0.4	0.5	-0.7	1.6	-0.0	-0.3	0.6	-0.6	0.6	-0.0	-1.8	-0.2
Loud music exposure frequency	0.3	0.3	0.9	-0.5	0.3	0.2	-0.8	0.6	-0.4	0.9	-1.0	0.3	-0.5	0.2	-0.2
Qualifications: O levels/GCSEs or equivalent	4.5	7.1	10.7	-2.9	2.4	2.4	-0.4	2.8	-3.3	3.0	-2.5	3.1	-3.2	0.5	-3.2
Mouth/teeth dental problems: Bleeding gums	0.9	1.1	1.8	1.1	0.5	-1.3	0.3	-1.3	0.9	-1.0	1.0	-0.9	1.2	-1.3	1.2
Blood clot in the leg (DVT)	0.5	0.7	3.4	-0.8	-0.1	-0.3	1.7	-0.3	-0.3	0.4	-0.5	0.7	0.0	-1.8	-0.2
Medication: Paracetamol	0.3	0.4	1.0	0.1	0.9	0.4	-0.6	1.0	-0.6	0.4	0.1	0.1	-0.8	1.0	-0.8
Headache pain in last month	0.7	1.2	2.6	-0.3	1.4	0.3	-0.7	1.3	-1.3	0.7	-0.1	0.4	-1.6	1.6	-1.6
Medication for cholesterol, blood pressure or diabetes	0.5	0.8	4.8	-0.6	2.2	0.4	-0.6	0.5	-0.8	1.0	-0.9	0.8	-0.7	0.0	-0.2
Glaucoma (self-reported)	1.0	1.2	4.9	-0.2	1.2	0.2	-1.8	0.8	-0.9	0.7	0.1	0.1	-1.2	2.2	-1.1
Gout (self-reported)	0.5	0.7	1.5	0.6	1.1	0.1	1.0	-0.4	0.9	-1.2	0.8	-0.5	0.9	-1.0	0.6
Hypothyroidism/myxoedema (self-reported)	0.1	0.2	1.7	0.3	-1.3	-0.6	0.1	-0.0	0.1	-0.1	0.0	0.1	0.2	-0.0	0.2
Medication: Amlodipine	0.3	0.4	2.1	0.4	-0.8	-1.5	-0.3	-1.0	0.4	-0.3	0.2	-0.5	0.3	0.3	0.4
Medication: Ventolin 100micrograms inhaler	3.4	4.4	7.8	-2.3	1.2	1.8	0.7	2.6	-2.2	2.8	-2.4	2.7	-2.2	-0.4	-2.3
Birth weight	0.4	0.8	1.4	1.0	-1.0	-0.6	-1.2	-1.1	0.9	-0.8	1.0	-1.1	0.3	1.0	0.3
Chronic bronchitis/emphysema (mother)	0.2	0.2	0.7	-0.4	0.7	0.0	0.0	-0.3	0.2	0.1	-0.8	0.4	0.2	-0.6	0.5
High blood pressure (siblings)	0.5	0.8	1.8	0.8	-1.3	-0.2	0.3	-0.9	1.3	-1.0	0.7	-0.7	1.1	-0.5	1.1
Forced vital capacity (FVC), Best measure	0.5	1.7	3.6	-1.8	-0.3	-0.7	0.5	0.1	-1.6	1.5	-1.9	1.9	-1.5	-1.1	-1.0
Body fat percentage	0.8	3.1	6.1	-1.7	1.2	1.4	2.5	1.7	-1.4	2.0	-1.6	2.2	-0.9	-2.3	-1.3
Leg fat percentage (right)	0.6	2.0	3.6	-1.2	1.4	1.5	1.9	1.8	-1.2	1.6	-1.0	1.7	-0.9	-1.3	-1.3
Arm fat-free mass (right)	0.8	3.9	21.9	-0.7	-0.9	-0.1	4.5	-0.3	0.1	0.0	-0.1	1.2	1.2	-4.7	0.3
Exposure to tobacco smoke outside home	0.4	0.6	2.0	-1.0	1.4	0.4	0.2	0.3	-0.5	0.6	-1.4	0.6	-0.4	-0.5	-0.6
Comparative body size at age 10	1.8	5.1	8.0	-2.2	2.1	1.7	-2.3	1.9	-2.7	2.2	-1.6	1.7	-2.8	2.8	-2.5
Number of full brothers	0.2	0.2	0.4	-0.5	0.2	-0.6	0.5	0.2	-0.6	0.4	-0.2	0.5	-0.6	0.3	-0.5
Worry too long after embarrassment	0.7	1.1	4.5	1.2	-1.8	0.3	-2.1	0.3	-0.1	-0.1	1.3	-0.3	-0.2	1.5	-0.1
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.4	1.6	-0.5	1.2	0.4	0.7	0.7	-0.3	0.4	-0.2	0.4	-0.4	-0.4	-1.0
Wheeze or whistling in the chest in last year	0.9	1.7	3.9	-1.5	-0.5	0.4	2.0	1.4	-1.3	1.3	-1.6	1.5	-1.0	-0.6	-1.4
Number of children fathered	0.5	0.6	3.0	-0.8	-1.7	0.5	0.9	-0.2	-0.1	0.2	-0.8	0.5	0.3	-1.0	0.6
Reason for reducing amount of alcohol drunk: Health precaution	1.3	1.6	3.8	1.2	-0.5	-1.9	-0.3	-1.9	1.4	-1.0	1.0	-1.6	1.3	-0.3	1.2
Age at first live birth	0.9	1.5	3.6	1.1	0.4	-1.8	-1.6	-1.9	0.9	-1.2	0.9	-1.3	0.9	0.7	1.4
Pulse wave peak to peak time	0.9	1.0	5.2	1.0	-0.5	-0.3	-2.3	-0.5	0.2	-0.6	1.2	-0.7	-0.0	1.7	0.3
Health satisfaction	0.1	0.1	0.4	0.3	-0.7	0.0	0.7	0.4	-0.1	0.3	0.3	0.1	-0.1	-0.5	-0.4
Shortness of breath walking on level ground	1.2	1.4	3.0	-1.2	1.4	-0.7	0.5	0.7	-1.7	1.7	-1.4	1.2	-1.3	0.1	-1.2
Qualifications: College or University degree	0.2	0.6	1.3	-0.3	0.7	0.4	-0.8	0.7	-1.0	0.9	-0.1	0.4	-1.1	1.1	-1.1
Eye problems/disorders: None of the above	1.3	1.5	9.5	-0.2	-0.6	0.6	2.6	-0.1	0.6	-0.1	0.1	0.6	0.9	-3.1	0.3
Mouth/teeth dental problems: Loose teeth	0.8	0.9	1.8	-0.9	-0.0	0.9	-0.7	1.3	-1.2	1.0	-0.9	1.3	-1.2	0.7	-0.9
Emphysema/chronic bronchitis	0.5	0.6	2.7	-0.6	-0.2	-0.4	-0.4	0.5	-0.9	0.6	-0.5	0.3	-0.9	1.6	-1.1
Medication for pain relief, constipation, heartburn	0.1	0.2	1.3	-0.8	-0.2	0.5	-0.4	-0.0	0.0	0.5	-1.1	0.4	-0.1	-0.3	0.1
Neck or shoulder pain in last month	0.2	0.3	1.1	0.7	-0.7	-0.3	-0.0	-0.6	0.2	-0.7	1.0	-0.9	0.3	0.4	0.1
Medication: Blood pressure	0.2	0.4	0.7	-0.7	-0.6	0.8	0.8	0.8	-0.6	0.3	-0.4	0.8	-0.4	-0.2	-0.6
Angina (self-reported)	0.8	1.0	2.6	1.3	-1.6	0.3	-0.0	-0.2	1.1	-0.8	1.4	-0.9	1.2	-0.7	1.2
Migraine (self-reported)	2.2	2.7	5.9	-1.2	-0.1	0.7	-0.2	2.2	-2.0	2.2	-0.9	1.9	-2.4	1.0	-2.2
Medication: Ibuprofen	0.1	0.2	0.6	0.7	0.2	-0.4	0.4	0.3	-0.4	-0.1	0.8	0.2	-0.1	-0.1	-0.1
Medication: Allopurinol	0.4	0.6	1.7	0.7	1.3	0.2	0.9	-0.0	0.6	-1.1	0.8	-0.5	0.6	-0.8	0.4
Medication: Omeprazole	0.2	0.2	1.4	-0.0	0.5	-0.7	1.2	-0.1	0.1	0.1	-0.3	-0.0	0.0	-0.6	-0.5
Medication: Seretide 50 evohaler	0.2	0.2	0.5	-0.6	0.1	0.4	0.5	0.2	-0.2	0.6	-0.7	0.4	-0.1	-0.5	-0.3
Mean time to correctly identify matches	0.4	0.8	1.6	0.7	-0.3	-1.2	-0.4	-1.0	0.9	-1.2	0.5	-1.0	1.0	0.6	1.1
Heart disease (mother)	3.3	4.0	7.6	-2.0	1.4	2.7	0.0	2.4	-1.9	2.5	-1.8	2.8	-1.9	-1.1	-1.9
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.3	0.3	1.5	0.3	0.8	0.2	-1.2	0.2	-0.1	0.1	0.2	-0.1	-0.3	1.2	-0.3
Whole body fat mass	0.7	3.1	11.1	-1.5	0.7	0.9	3.3	1.2	-1.1	1.6	-1.3	2.1	-0.4	-3.2	-1.0
Leg fat mass (right)	0.8	3.1	10.2	-1.6	1.1	1.1	3.2	1.5	-1.3	1.7	-1.3	2.1	-0.7	-2.7	-1.3
Arm predicted mass (right)	0.6	3.2	18.1	-0.6	-0.8	-0.2	4.1	-0.3	0.1	0.1	0.0	1.1	1.1	-4.2	0.3
Pulse rate, automated reading	0.6	2.1	4.7	-1.5	0.7	0.7	0.8	1.4	-1.8	1.7	-1.1	1.8	-1.9	-0.1	-2.2
Alcohol intake frequency.	0.3	0.7	1.7	-0.2	1.1	0.9	-0.6	0.9	-0.7	0.8	0.1	0.6	-1.1	0.9	-1.3
Comparative height size at age 10	0.3	1.6	7.8	0.1	-1.2	-2.8	0.7	-2.1	0.2	-0.4	0.2	0.1	0.7	-1.9	0.8
Number of full sisters	1.0	1.2	2.6	-0.8	0.4	1.1	0.3	1.6	-1.4	1.3	-0.9	1.2	-1.4	-0.0	-1.4
Suffer from ‘nerves’	0.2	0.4	2.7	0.4	-1.6	-0.7	0.3	-0.4	0.3	-0.4	0.4	-0.6	0.4	-0.0	0.4
Overall health rating	0.9	1.9	5.2	1.8	-0.6	-0.4	-0.3	-1.1	1.5	-1.9	2.3	-1.7	1.4	-0.0	1.2
Chest pain or discomfort	0.4	0.5	2.6	-0.1	-0.1	-1.0	1.6	-0.6	0.3	-0.2	-0.2	-0.1	0.4	-1.4	0.2
Had major operations	2.1	2.5	4.9	-1.4	1.7	-0.3	-0.0	1.6	-2.2	1.9	-1.7	1.7	-1.9	1.1	-1.8
Age at last live birth	0.2	0.3	1.0	0.1	0.3	-0.4	-0.6	-0.9	0.3	-0.4	-0.3	-0.5	0.5	0.1	1.0
Family relationship satisfaction	0.9	1.1	5.2	-0.9	2.3	-0.3	-0.0	0.5	-0.8	1.2	-1.4	0.4	-1.1	0.3	-1.2
Leg pain on walking	3.1	3.9	6.7	-2.0	0.6	1.1	1.5	2.5	-2.2	2.4	-2.0	2.5	-2.2	-0.3	-2.6
Qualifications: NVQ or HND or HNC or equivalent	1.5	1.9	3.3	-1.5	1.0	1.2	-0.7	1.3	-1.5	1.7	-1.3	1.2	-1.8	1.0	-1.6
Commuting to job workplace: Car/motor vehicle	1.5	1.7	3.5	-1.2	-0.4	0.6	-0.5	1.4	-1.8	1.9	-1.2	1.3	-1.8	0.8	-1.6
Illness, injury, bereavement, stress in last 2 years	0.7	0.8	2.1	0.5	-0.4	0.1	1.4	-0.6	1.2	-1.1	0.5	-0.9	1.4	-1.1	0.7
Medication: Aspirin	2.1	2.8	4.9	1.6	-2.2	-1.7	1.4	-1.6	1.7	-2.1	1.9	-1.7	1.8	-0.7	1.3
Supplements: Vitamin C	0.6	0.7	1.5	-1.1	0.8	-0.3	0.4	0.7	-0.8	0.9	-1.2	0.5	-0.9	-0.1	-1.2
Knee pain experienced in last month	0.5	0.8	4.0	0.0	-0.5	0.2	-1.4	0.9	-0.3	0.2	0.1	0.0	-1.0	2.0	-1.0
Hypertension (Self-reported)	0.2	0.6	3.9	-0.2	0.4	-0.1	2.0	-0.4	0.1	-0.8	0.1	0.2	0.4	-1.3	0.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.5	0.5	3.0	0.0	0.7	-0.6	1.7	-0.3	0.3	-0.1	-0.1	0.0	0.4	-1.5	-0.3
Illnesses of father: Heart disease	1.9	2.7	4.0	-2.0	1.6	1.7	1.9	1.2	-1.2	1.4	-1.7	2.0	-1.1	-1.9	-1.5
Illnesses of siblings: Diabetes	0.1	0.1	0.6	0.0	-0.4	-0.8	-0.4	-0.0	-0.3	0.4	0.1	0.4	-0.4	0.1	-0.5
Smoking status: Previous	0.9	1.3	2.7	-1.1	0.8	1.4	-0.3	1.3	-1.2	1.4	-0.9	1.1	-1.4	0.7	-1.6
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.5	2.4	-0.5	-1.5	-0.2	0.7	-0.5	-0.0	0.2	-0.6	0.3	0.1	-1.3	0.3
Whole body fat-free mass	0.5	3.1	16.7	-0.9	-0.4	-0.5	4.0	-0.5	-0.2	0.2	-0.3	1.2	0.8	-4.1	-0.0
Leg fat-free mass (right)	0.7	3.7	18.2	-1.6	0.0	-0.1	4.3	0.0	-0.8	1.0	-0.9	1.8	0.2	-4.2	-0.7
Arm fat percentage (left)	0.8	3.2	5.2	-1.6	1.4	1.6	2.2	1.9	-1.5	2.2	-1.5	2.3	-1.1	-2.0	-1.5
Average weekly red wine intake	0.1	0.1	0.8	-0.1	-0.3	0.9	-0.0	0.5	-0.2	0.4	-0.0	0.4	-0.2	-0.0	-0.2
Handedness (chirality/laterality): Left-handed	0.6	0.7	1.5	-0.5	1.1	-1.1	0.1	0.1	-1.0	1.2	-0.7	0.6	-0.8	0.4	-1.2
Mood swings	0.1	0.2	0.4	0.6	-0.3	-0.7	-0.6	-0.2	0.2	0.3	0.4	-0.0	0.3	-0.2	0.2
Loneliness, isolation	0.7	0.9	4.2	-0.2	1.2	-0.5	2.1	-0.0	0.2	0.1	-0.3	0.0	0.7	-2.0	0.3
Long-standing illness, disability or infirmity	1.5	2.3	5.3	-1.2	1.1	1.2	-0.5	1.8	-2.0	1.5	-0.8	1.3	-2.2	1.2	-2.3
Ever had bowel cancer screening	0.5	0.5	1.6	0.2	-0.6	0.8	0.6	-0.2	1.0	-0.6	0.6	-0.3	1.0	-1.3	0.7
Diabetes diagnosed by doctor	0.5	0.8	1.5	0.6	-0.7	-0.7	1.1	-1.0	1.1	-1.0	0.8	-0.8	1.2	-0.9	0.8
Ever had stillbirth, spontaneous miscarriage or termination	0.1	0.1	0.4	0.3	-0.6	0.3	-0.4	-0.1	-0.2	0.2	0.6	0.3	-0.2	0.1	-0.2
Friendships satisfaction	0.1	0.1	0.4	0.4	0.4	-0.3	0.1	-0.2	0.4	-0.2	0.0	-0.7	0.4	-0.5	0.2
Qualifications: nursing, teaching	0.1	0.2	0.6	0.1	0.3	-0.0	-0.6	0.2	-0.4	0.6	0.4	0.2	-0.6	0.6	-0.8
Commuting to job workplace: Walk	0.4	0.5	1.5	-0.1	1.2	0.6	1.2	0.2	0.2	-0.2	-0.1	0.5	0.6	-1.2	0.3
Eye problems/disorders: Cataract	0.2	0.2	0.9	0.3	-0.7	-0.4	-1.0	-0.4	0.2	-0.1	0.1	-0.6	0.0	0.7	0.4
Mouth/teeth dental problems: Mouth ulcers	0.8	1.3	5.3	0.9	-0.5	-2.3	-1.3	-1.7	0.5	-0.6	0.5	-1.0	0.6	1.0	1.2
Medication for cholesterol	1.8	2.7	5.8	-1.9	0.3	1.0	-0.0	2.0	-2.0	2.4	-2.4	2.0	-1.6	-0.2	-1.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.1	0.1	0.3	0.4	-0.1	0.2	-0.4	-0.3	0.4	-0.2	0.6	-0.5	0.3	0.6	0.2
Back pain experienced in last month	0.2	0.4	1.7	-0.5	-0.2	-0.2	1.3	0.1	-0.2	-0.1	-0.5	0.5	0.1	-1.3	0.1
Mineral and other dietary supplements	0.5	0.7	1.6	-0.7	0.9	1.2	-0.6	0.7	-0.8	0.9	-0.2	1.3	-1.0	0.5	-0.6
Breast cancer (self-reported)	0.3	0.4	1.2	0.4	-0.7	-1.1	0.6	-0.7	0.5	-0.8	0.3	-0.8	0.5	-0.4	0.3
Asthma (self-reported)	0.6	1.3	3.6	-0.6	-0.2	0.7	-1.2	1.0	-1.4	1.3	-0.3	0.7	-1.5	1.9	-1.4
Osteoporosis (self-reported)	0.8	1.0	2.9	-0.2	1.1	0.6	-1.4	1.2	-0.9	0.7	0.0	0.5	-1.2	1.7	-1.2
Osteoarthritis (self-reported)	0.3	0.4	0.9	-0.3	0.9	0.9	-0.5	0.8	-0.2	0.4	-0.7	0.9	-0.4	-0.6	-0.5
Medication: Aspirin	1.2	1.6	3.1	1.2	-1.8	-1.1	1.1	-1.1	1.2	-1.6	1.6	-1.3	1.2	-0.3	0.7
Medication: Gliclazide	1.0	1.1	2.1	1.1	-0.3	-1.4	0.5	-0.9	1.0	-1.5	0.8	-1.3	1.2	0.3	1.3
Illnesses of father: None of the above (group 1)	0.4	0.5	2.1	1.0	-0.4	-1.4	-0.1	-0.4	0.2	-0.7	0.7	-0.8	0.6	0.6	0.7
Smoking status: Current	0.7	1.1	5.5	0.9	-2.3	-0.8	1.0	-0.6	0.8	-0.7	1.3	-0.5	0.8	-0.7	0.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.8	1.8	4.5	-2.0	1.1	0.6	0.1	0.8	-1.5	1.7	-2.1	1.7	-1.3	-0.4	-0.9
Whole body water mass	0.6	3.2	17.1	-1.0	-0.4	-0.4	4.1	-0.4	-0.3	0.3	-0.4	1.3	0.7	-4.1	-0.1
Leg predicted mass (right)	0.7	3.7	18.0	-1.6	0.1	-0.1	4.2	0.0	-0.8	1.0	-0.9	1.8	0.2	-4.2	-0.6
Arm fat mass (left)	0.8	3.4	10.0	-1.6	1.0	1.2	3.2	1.4	-1.3	1.9	-1.2	2.3	-0.6	-3.1	-1.2
Number of self-reported non-cancer illnesses	0.3	0.5	1.3	-0.5	-0.8	0.4	0.5	0.8	-0.7	0.5	-0.3	0.8	-0.9	-0.1	-1.1
Average weekly champagne plus white wine intake	0.0	0.0	0.1	0.1	0.2	-0.1	-0.1	-0.3	0.1	0.0	0.1	-0.2	-0.1	-0.1	-0.1
Miserableness	0.1	0.2	0.7	0.6	0.8	-0.5	-0.0	-0.5	0.3	0.1	0.5	-0.3	0.3	-0.5	0.1
Guilty feelings	0.6	0.9	1.7	-1.3	-0.4	-0.3	0.1	0.9	-1.3	1.0	-1.1	1.1	-1.3	0.7	-1.2
Wears glasses or contact lenses	0.5	0.6	2.0	0.4	-0.9	-1.4	-0.3	-0.8	0.5	-1.0	-0.1	-0.8	0.6	0.6	1.0
Ever taken oral contraceptive pill	0.1	0.1	0.2	-0.1	-0.1	0.4	0.3	-0.0	0.2	-0.4	0.0	0.2	0.2	-0.5	0.4
Hearing aid user	0.1	0.1	0.8	-0.0	0.2	0.9	0.3	0.1	0.3	0.2	0.5	-0.0	0.1	-0.3	-0.3
Mother’s age at death	0.4	0.5	1.3	0.7	-0.7	0.8	0.8	0.3	0.8	-1.1	0.7	-0.9	0.8	-0.0	0.5
Financial situation satisfaction	0.8	1.0	2.7	-1.1	1.6	0.2	-0.7	0.4	-1.0	1.3	-1.2	1.0	-1.3	0.1	-1.0
Tinnitus: Yes, now most or all of the time	1.3	1.6	3.1	-1.6	0.9	1.2	1.5	1.3	-0.8	1.1	-1.8	1.5	-0.8	-1.1	-1.0
Commuting to job workplace: Public transport	0.4	0.5	2.3	0.1	1.3	-0.2	1.0	-0.4	0.5	-0.4	-0.1	-0.1	0.6	-1.5	0.2
Eye problems/disorders: Glaucoma	2.0	2.4	11.8	0.1	1.6	-0.3	-2.7	0.8	-1.1	0.8	-0.0	-0.2	-1.6	3.4	-1.1
Medication: Blood pressure	0.4	0.7	2.1	1.1	-0.4	0.1	0.2	-0.7	1.0	-1.4	1.2	-0.9	0.8	0.1	0.8
Pain type(s) experienced in last month: Hip pain	0.1	0.1	0.4	-0.2	0.2	0.5	0.0	0.6	-0.3	0.3	-0.1	0.4	-0.5	0.2	-0.6
Supplements: Fish oil (including cod liver oil)	0.8	1.1	3.0	0.6	-1.7	-0.5	0.9	-0.9	1.2	-0.9	0.3	-1.2	1.4	-1.1	0.7
High cholesterol (Self-reported)	1.1	1.9	10.6	0.1	-1.7	0.1	2.6	-0.3	0.8	-0.4	0.3	0.3	1.1	-3.2	0.6
Medication: Bendroflumethiazide	0.4	0.6	2.0	0.1	-1.4	-0.6	1.3	-0.5	0.5	-0.9	-0.1	-0.8	0.6	-0.4	0.4
Medication: Paracetamol	0.3	0.4	1.7	1.1	0.3	-0.1	-0.5	0.3	0.2	-0.5	1.3	-0.9	0.1	1.0	0.1
Medication: Lisinopril	0.5	0.6	1.9	0.7	-0.6	-0.5	0.4	-1.3	0.9	-1.4	1.0	-0.7	0.5	0.2	0.3
Medication: Atorvastatin	0.4	0.5	1.3	0.5	0.4	-1.0	1.1	-0.7	0.4	-0.9	0.5	-0.5	0.7	-0.7	0.4
Illnesses of father: High blood pressure	0.7	0.9	1.8	-1.2	0.8	0.7	-0.7	0.4	-0.9	0.9	-1.2	0.9	-1.3	0.5	-1.1
Alcohol drinker status: Never	0.3	0.3	1.6	-0.4	0.4	0.4	0.9	0.3	0.1	0.1	-0.7	0.4	0.4	-1.3	0.2
Ever smoked	0.1	0.3	0.6	-0.5	-0.0	0.4	0.1	0.8	-0.6	0.7	-0.3	0.4	-0.7	0.1	-0.7
Basal metabolic rate	0.6	3.2	16.7	-1.1	-0.1	-0.2	4.0	-0.2	-0.5	0.6	-0.5	1.5	0.4	-4.1	-0.4
Leg fat percentage (left)	0.6	2.3	4.4	-1.3	1.2	1.6	2.1	1.7	-1.2	1.8	-1.1	1.8	-0.8	-1.8	-1.2
Arm fat-free mass (left)	0.6	3.0	16.4	-0.7	-0.2	-0.3	4.0	-0.2	-0.3	0.4	-0.2	1.3	0.6	-4.0	-0.2
Number of operations (self-reported)	0.1	0.1	0.6	-0.1	0.5	-0.7	0.6	-0.1	0.0	-0.2	-0.3	0.1	0.1	0.1	0.3
Average weekly beer plus cider intake	0.1	0.1	0.4	-0.1	0.6	0.5	-0.3	0.4	0.0	-0.1	0.1	0.6	-0.1	-0.1	0.1
Irritability	0.3	0.4	1.3	-0.3	-1.0	0.8	0.1	0.7	-0.3	0.8	-0.3	0.9	-0.1	-1.1	-0.4
Risk taking	0.5	0.7	1.5	-0.7	-0.3	1.2	-0.1	1.1	-0.6	1.0	-0.5	1.1	-0.9	-0.1	-1.0
Ever had prostate specific antigen (PSA) test	0.6	0.6	3.1	0.2	-1.8	-0.2	-1.2	-0.7	0.2	-0.1	0.5	-0.5	0.0	1.3	0.3
Fractured/broken bones in last 5 years	1.7	2.2	4.3	1.4	-0.4	-1.5	-0.3	-1.8	1.7	-2.1	1.3	-1.7	1.6	-0.3	1.8
Age started oral contraceptive pill	0.3	0.4	1.7	0.0	0.7	0.8	-0.9	0.3	-0.0	-0.2	0.3	-0.3	-0.3	1.3	-0.5
Diastolic blood pressure, automated reading	1.6	4.9	8.8	-2.6	2.2	3.0	1.7	2.6	-2.1	2.1	-2.4	2.7	-1.8	-1.1	-1.8
Ever depressed for a whole week	0.4	0.5	1.2	-0.6	0.6	-0.5	-0.4	0.2	-1.0	1.1	-0.8	0.5	-1.0	0.7	-0.8
Unable to work because of sickness or disability	0.3	0.4	1.1	0.8	0.3	0.4	-0.7	0.3	0.3	-0.7	1.1	-0.6	0.3	0.6	0.4
Commuting to job workplace: Cycle	1.0	1.2	6.5	-0.5	2.5	1.0	-0.9	1.0	-0.7	0.4	-0.2	0.6	-1.0	1.3	-1.0
Myopia	0.7	1.0	2.4	0.9	-1.6	-0.9	-0.8	-1.2	1.1	-0.7	1.1	-0.9	1.0	-0.0	1.1
Vascular/heart problems diagnosed by doctor	0.3	0.8	1.6	-0.7	-0.1	0.8	-1.2	1.0	-0.7	1.3	-0.9	0.6	-1.0	1.0	-0.8
Cholesterol lowering medication	1.1	1.6	6.8	0.5	-0.3	-0.3	2.5	-0.9	1.1	-0.7	0.6	-0.5	1.4	-2.6	0.9
Medication: Omeprazole (e.g. Zanprol)	0.1	0.1	0.6	0.0	-0.4	-0.7	0.3	0.1	-0.2	0.3	-0.1	0.1	-0.4	-0.0	-0.8
Pain experienced in last month	0.2	0.4	1.3	-0.8	-0.0	-0.1	0.7	-0.5	0.3	0.1	-1.1	0.3	0.5	-0.7	0.8
Supplements: Calcium	0.3	0.4	1.1	0.7	0.6	-0.3	-0.8	-0.0	0.3	-0.6	0.7	-0.9	0.1	1.0	0.3
Basal cell carcinoma (self-reported)	0.4	0.5	1.7	0.2	0.4	-0.3	-0.7	-1.0	1.0	-0.7	-0.1	-0.6	0.8	0.2	1.3
Heart attack/myocardial infarction (self-reported)	2.0	2.6	4.1	2.0	-1.1	-1.6	0.3	-1.9	1.8	-1.7	1.8	-2.0	1.8	-0.3	1.7
Deep venous thrombosis (DVT) (self-reported)	0.3	0.4	2.3	-0.4	-0.1	-0.5	1.2	-0.4	-0.1	0.2	-0.1	0.4	0.1	-1.5	0.1
Heart disease (siblings)	0.7	0.9	5.1	-0.5	-0.3	0.7	2.0	0.2	0.2	-0.4	-0.2	0.7	0.2	-2.3	-0.2
Alcohol drinker status: Previous	0.1	0.2	0.5	0.3	-0.2	-0.6	-0.5	-0.4	0.5	-0.3	0.2	-0.4	0.0	0.7	0.2
Pack years of smoking	0.3	0.4	1.1	-0.7	0.4	-0.3	1.1	0.1	-0.5	0.8	-0.8	0.9	-0.2	-0.9	-0.3
Impedance of whole body	0.4	2.1	12.3	0.6	0.6	-1.3	-3.5	-0.8	0.1	-0.0	-0.1	-1.0	-0.6	2.9	0.3
Leg fat mass (left)	0.8	3.1	10.7	-1.6	1.0	1.1	3.3	1.3	-1.2	1.6	-1.2	2.1	-0.5	-3.0	-1.1
Arm predicted mass (left)	0.6	2.8	15.6	-0.6	-0.5	-0.4	4.0	-0.4	-0.0	0.1	-0.1	1.0	0.9	-3.9	0.1