TWAS hub - NT5M

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1300	0.0380	5.6e-07	0.097	0.061	0.104	0.099	0.097	8.5e-12	6.4e-08	1.4e-12	4.1e-12	7.1e-12
2	GTEx	Heart Left Ventricle	0.1287	0.0536	1.3e-03	0.005	NA	0.023	NA	0.039	1.6e-01	NA	2.2e-02	NA	3.7e-03
3	GTEx	Whole Blood	0.4180	0.0480	0.0e+00	0.327	NA	0.327	NA	0.328	7.5e-31	NA	7.5e-31	NA	5.4e-31
4	METSIM	Adipose	0.1374	0.0371	3.7e-06	0.071	0.039	0.069	0.067	0.076	7.2e-11	1.6e-06	1.8e-10	2.5e-10	1.9e-11
5	NTR	Blood	0.0842	0.0185	3.7e-12	0.063	0.048	0.058	0.061	0.060	2.0e-19	2.4e-15	4.7e-18	5.5e-19	1.3e-18
6	ROSMAP	Brain Pre-frontal Cortex	0.0894	0.0349	1.3e-03	0.075	0.016	0.081	0.073	0.077	6.5e-10	3.4e-03	1.2e-10	9.8e-10	4.0e-10
7	YFS	Blood	0.3977	0.0346	0.0e+00	0.330	0.329	0.363	0.357	0.358	7.1e-112	9.8e-112	4.8e-126	3.0e-123	1.3e-123
8	TCGA	Head and Neck Squamous Cell Carcinoma	0.1176	0.0485	2.6e-04	0.056	0.027	0.056	NA	0.062	6.7e-07	4.5e-04	7.2e-07	NA	1.6e-07
9	TCGA	Kidney Renal Clear Cell Carcinoma	0.1373	0.0467	5.4e-04	0.040	0.028	0.040	NA	0.032	2.5e-05	3.4e-04	2.6e-05	NA	1.6e-04
10	TCGA	Brain Lower Grade Glioma	0.0803	0.0333	2.6e-04	0.024	0.036	0.035	NA	0.029	8.5e-04	5.3e-05	7.5e-05	NA	2.4e-04
11	TCGA	Soft Tissue Sarcoma	0.1590	0.0610	5.7e-04	0.002	0.047	0.026	NA	0.011	2.5e-01	8.4e-04	1.1e-02	NA	6.7e-02

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11
Schizophrenia vs Biploar Disorder	5.0	6.7	13.2	-3.0	0.6	-3.3	-2.1	-3.3	-2.4	-3.6	-2.1	-3.3	-0.3	-1.7
Ever smoked	3.5	6.1	15.3	2.4	-3.0	3.9	1.1	3.6	1.0	3.9	1.1	2.0	-0.4	1.3
Past tobacco smoking	3.2	5.8	16.3	-2.1	2.5	-4.0	-0.7	-3.7	-0.9	-4.0	-0.6	-1.9	0.5	-1.1
Pulse rate, automated reading	3.1	10.0	29.6	-5.4	-2.9	-3.0	-2.7	-3.3	-3.0	-3.9	-3.9	-0.3	-2.0	1.0
Tinnitus: Yes, but not now, but have in the past	3.0	3.2	7.1	-0.3	2.6	1.6	-1.0	1.8	-1.8	1.8	-1.8	-1.5	-2.7	1.5
Serious illness, injury or assault of a close relative in last 2 years	3.0	3.5	11.2	0.6	-1.8	3.2	-0.8	3.4	-0.7	3.0	-1.0	0.4	-0.9	1.0
Knee pain experienced in last month	3.0	4.6	9.4	-1.8	0.1	-2.0	-2.7	-1.8	-3.0	-2.1	-2.7	-3.1	-1.6	-1.0
Ever taken oral contraceptive pill	2.9	3.2	9.0	-1.6	1.2	0.7	-2.8	0.6	-3.0	0.8	-2.2	-1.8	-2.0	-0.7
Smoking status: Previous	2.8	4.2	12.9	1.8	-1.6	3.6	0.7	3.4	0.8	3.6	0.4	1.3	-0.6	0.3
Had major operations	2.7	3.2	7.5	2.7	-1.1	2.1	1.8	2.0	2.1	1.8	2.0	0.9	1.5	-0.0
Mother’s age at death	2.7	3.4	10.6	2.0	-1.4	2.5	0.5	2.9	1.0	3.3	1.0	1.0	1.6	-0.6
Medication: Gliclazide	2.5	2.8	4.6	-1.2	2.1	-1.7	-2.0	-1.6	-1.6	-1.8	-1.6	-2.1	-1.4	0.4
Pulse rate	2.3	3.8	8.4	-2.9	-1.8	-2.3	-1.6	-2.3	-1.8	-2.8	-1.8	-0.4	-1.1	1.4
Osteoporosis (self-reported)	2.3	2.9	8.5	1.4	-1.2	2.5	0.6	2.6	0.0	2.9	0.1	2.0	-0.1	1.6
Happiness	2.2	2.6	7.1	-1.8	1.4	0.1	-2.1	0.1	-2.7	-0.0	-2.5	-1.4	-1.9	-0.8
Eye problems/disorders: Cataract	2.2	2.6	7.3	1.1	-2.4	2.7	-0.9	2.6	0.1	2.3	0.1	0.8	0.8	-0.2
Ever unenthusiastic/disinterested for a whole week	2.1	2.6	7.3	0.5	-1.6	1.8	-1.3	2.2	-1.0	1.9	-0.7	0.7	-1.8	2.7
Diabetes (father)	1.9	2.4	6.0	-1.6	0.4	-2.4	-0.7	-2.4	-0.6	-2.4	-0.4	-1.5	-1.5	-0.8
Miserableness	1.9	3.4	9.0	-0.1	-0.6	2.0	-3.0	2.4	-1.8	1.3	-2.1	-2.4	-0.9	-1.2
Diverticular disease/diverticulitis (self-reported)	1.8	2.2	8.3	-1.5	0.5	-0.2	-1.7	-0.1	-2.0	-0.5	-2.3	-0.5	-2.9	0.9
Seen a psychiatrist for nerves, anxiety, tension or depression	1.8	2.4	5.5	-2.3	-1.5	-1.6	-1.3	-1.5	-1.3	-1.8	-1.5	-0.5	-1.7	1.3
Medication: Blood pressure	1.8	3.5	11.2	1.8	3.1	0.0	2.2	-0.2	3.4	-0.4	1.9	1.7	1.2	-1.1
Medication: Omeprazole (e.g. Zanprol)	1.8	2.2	4.8	-2.2	0.9	-1.8	-1.2	-1.6	-1.8	-1.7	-0.8	-1.9	-0.6	0.5
Number of full brothers	1.7	2.1	5.6	0.1	0.4	1.3	-2.4	1.3	-2.3	1.0	-2.1	-0.3	-0.9	1.5
Medication: Omeprazole	1.7	2.0	5.7	-1.9	0.8	-1.8	-0.8	-1.6	-1.6	-1.7	-0.4	-2.4	-0.3	0.0
Body Mass Index (BMI) (2010)	1.6	2.1	5.1	1.7	0.6	2.0	1.3	2.0	1.3	2.3	0.7	1.5	0.7	-0.5
HbA1C	1.6	1.8	4.6	-1.0	1.6	-0.9	-1.3	-1.0	-1.4	-1.3	-1.4	-2.1	-0.9	-1.2
Heel T-Score	1.6	12.7	28.6	5.3	2.6	3.3	2.4	3.5	3.2	4.4	4.2	-0.7	3.6	-3.7
Family relationship satisfaction	1.6	2.0	3.5	-0.6	1.4	1.9	-1.2	1.7	-1.6	1.2	-1.8	-0.8	-1.8	-0.7
Alcohol drinker status: Never	1.6	1.9	5.0	-0.8	-1.2	-1.9	1.6	-2.2	1.7	-1.2	1.7	0.6	0.9	-0.2
Pain experienced in last month	1.6	2.7	5.3	2.2	-0.9	1.3	1.9	1.2	1.6	1.9	2.1	2.3	1.0	0.6
Alcohol drinker status: Previous	1.6	1.8	5.1	-0.8	0.3	0.7	-2.1	0.9	-2.3	0.7	-1.7	-1.6	-1.5	0.0
Bipolar Disorder (2018)	1.5	2.4	7.6	0.6	-0.6	2.5	-0.2	2.8	0.0	2.3	-0.3	1.8	-0.8	1.7
Smoking Status	1.5	3.7	10.2	1.9	-1.8	3.1	0.7	3.2	0.3	3.1	0.6	0.9	-0.8	1.4
Medication: Co-codamol	1.5	1.8	5.0	-1.0	-1.4	-2.2	-0.9	-1.9	-0.8	-2.0	-0.5	-1.1	-0.6	0.8
Medication: Ramipril	1.5	2.0	6.0	0.4	2.0	-0.7	0.5	-1.2	1.3	-1.5	0.9	-0.6	2.1	-2.4
Gout (self-reported)	1.5	2.1	7.5	1.5	0.2	0.3	1.5	0.1	2.7	0.5	1.8	1.4	2.2	0.5
Number of full sisters	1.5	1.8	5.9	-0.8	0.9	0.6	-1.8	0.1	-1.4	0.2	-2.4	-1.0	-2.4	0.1
Medication: Aspirin	1.5	2.0	4.5	1.2	1.5	1.4	1.5	1.0	1.8	1.1	1.4	2.1	1.3	-0.7
Commuting to job workplace: Public transport	1.5	1.8	5.5	-1.6	0.3	-1.7	-1.0	-1.6	-1.3	-1.5	-1.0	-0.2	-0.0	2.3
Lung FEV1/FVC ratio	1.4	7.2	19.9	-4.5	0.6	-0.3	-4.0	-1.0	-3.2	-1.9	-4.3	-1.9	-2.1	-1.3
Sensitivity / hurt feelings	1.4	2.4	7.2	1.9	-0.3	2.7	-0.9	2.6	0.0	2.2	-0.0	0.8	1.3	-0.5
Alcohol intake versus 10 years previously	1.4	2.0	4.5	-1.7	0.9	-0.9	-2.1	-0.8	-2.0	-1.3	-1.6	-1.8	-1.2	0.2
Father’s age at death	1.4	1.8	3.8	-2.0	-1.8	-1.7	-0.4	-1.6	-0.9	-1.3	-1.0	0.5	-1.1	1.7
Pulse wave reflection index	1.4	1.7	4.5	1.9	1.0	-0.3	2.1	0.2	2.0	0.3	1.8	0.1	1.1	-0.8
Alzheimer’s Disease (in father)	1.3	1.4	4.1	1.3	-0.8	0.7	1.1	0.7	0.7	0.9	1.6	0.9	2.0	1.3
Coronary Artery Disease (CAD)	1.3	1.5	4.8	1.0	-0.3	1.1	0.8	1.0	2.1	0.7	1.1	1.5	-0.6	2.2
Exposure to tobacco smoke at home	1.3	1.5	5.2	-0.1	0.5	0.4	-1.6	0.5	-1.4	0.4	-1.3	-1.0	-2.3	1.6
Medication: Amlodipine	1.3	1.8	6.5	1.7	0.6	0.4	2.2	0.2	1.8	0.6	2.6	0.7	0.9	1.0
Health satisfaction	1.3	1.7	4.8	-2.2	0.3	-0.4	-2.1	-0.6	-1.8	-0.8	-1.7	-1.1	-0.9	-0.3
Emphysema/chronic bronchitis	1.3	1.5	6.2	-0.6	-2.5	-0.2	-1.0	0.1	-1.7	-0.3	-1.4	-1.0	-0.8	1.5
Illnesses of siblings: Diabetes	1.3	1.6	4.1	-0.6	-1.7	-1.9	0.8	-2.0	0.7	-1.6	1.0	0.2	0.8	0.9
Major Depression (MDD)	1.2	1.5	5.6	-2.4	0.1	-0.6	-1.6	-0.5	-1.8	-0.5	-2.0	0.0	0.0	0.0
Mean Putamen Volume	1.2	1.4	2.5	1.3	1.1	1.2	1.5	1.2	1.1	1.2	1.4	0.0	1.6	0.5
Other serious medical condition/disability diagnosed by doctor	1.2	1.5	4.8	-2.2	-0.4	-1.4	-0.9	-1.3	-1.3	-1.0	-0.8	-0.5	-1.1	1.7
Ever highly irritable/argumentative for 2 days	1.2	1.4	3.5	1.7	-0.7	1.6	0.9	1.9	0.7	1.8	1.3	0.5	-0.0	0.4
Glaucoma (self-reported)	1.2	1.4	4.9	-1.0	0.1	-0.2	-1.3	-0.1	-2.2	-0.5	-1.9	-0.8	-1.7	0.2
Loneliness, isolation	1.2	1.7	3.2	-0.4	-1.0	1.5	-1.6	1.6	-1.5	1.0	-1.8	-1.1	-1.2	-0.9
Friendships satisfaction	1.2	1.5	3.5	-0.3	-0.1	1.9	-1.4	1.9	-1.2	1.5	-1.7	-0.5	-0.8	0.2
Commuting to job workplace: Walk	1.2	1.2	2.6	-1.6	-0.7	-0.9	-1.3	-1.0	-1.5	-1.0	-1.0	-1.0	-0.5	1.2
Eye problems/disorders: Glaucoma	1.2	1.5	3.1	-1.4	-0.4	-1.7	-0.9	-1.6	-1.5	-1.8	-1.4	-0.7	-0.4	0.2
Medication: Atorvastatin	1.2	1.5	3.2	1.7	1.7	0.9	1.1	0.6	1.8	0.5	1.3	1.3	1.1	0.4
Supplements: Calcium	1.2	1.3	5.7	0.0	-1.0	0.7	-0.1	0.7	-0.8	0.6	-0.5	1.6	-1.8	2.4
Prostate Cancer	1.1	1.5	3.6	-1.2	-0.7	-1.5	-1.4	-1.3	-1.3	-1.8	-0.6	-1.9	0.1	-0.2
Ever used hormone-replacement therapy (HRT)	1.1	1.4	4.3	-1.3	-1.1	-0.7	-1.2	-0.6	-0.6	-0.5	-1.3	-2.1	0.4	-1.7
Supplements: Zinc	1.1	1.2	3.9	0.4	-0.2	1.8	-0.5	2.0	-0.8	1.8	-0.7	0.4	-0.8	0.6
Fed-up feelings	1.1	2.1	7.2	1.2	0.4	2.6	-1.2	2.7	0.0	2.2	-0.4	-0.6	0.0	-0.9
Supplements: Glucosamine	1.1	1.5	5.3	0.6	-0.9	-0.9	2.3	-0.6	1.8	-0.4	1.5	1.2	0.9	1.0
Had menopause	1.1	1.4	4.2	0.7	-0.7	0.4	2.0	0.2	2.0	0.7	1.1	1.8	0.8	0.7
Breastfed as a baby	1.1	1.3	3.1	-1.0	-0.0	1.4	-1.5	1.1	-1.8	1.0	-1.5	-0.5	-1.2	-0.5
Medication: Ventolin 100micrograms inhaler	1.1	1.4	3.3	1.0	-0.9	1.4	-0.2	1.8	-0.6	1.7	-0.1	0.5	-1.6	1.6
Comparative body size at age 10	1.1	2.9	6.7	2.6	1.4	2.0	0.6	2.4	1.2	2.6	1.6	0.9	0.7	-1.2
Reason for reducing amount of alcohol drunk: Health precaution	1.1	1.3	4.0	-0.1	-2.0	1.2	-0.5	1.1	-0.6	1.2	-0.4	2.0	-0.6	0.9
Medication for cholesterol	1.1	1.7	7.7	-1.1	-2.8	-0.1	-1.2	0.1	-2.2	0.4	-1.2	-1.1	-0.7	0.3
Medication: Aspirin	1.1	1.5	3.2	1.1	0.6	0.9	1.5	0.6	1.8	0.7	1.4	1.8	1.3	-0.7
Illnesses of father: None of the above (group 1)	1.1	1.4	3.9	2.0	0.6	0.1	1.7	0.5	1.8	0.7	1.6	0.4	-0.8	0.9
Tinnitus: Yes, now most or all of the time	1.1	1.3	4.7	0.1	-0.6	1.6	-1.6	1.2	-0.9	1.4	-0.3	-0.2	0.5	-2.2
Supplements: Fish oil (including cod liver oil)	1.1	1.5	3.7	1.4	0.1	0.1	1.9	0.1	1.8	-0.0	1.4	1.1	1.9	0.0
High cholesterol (Self-reported)	1.1	2.0	9.6	0.3	1.4	0.1	1.0	-0.2	1.9	-0.5	1.0	2.1	3.1	-0.7
Ever had prostate specific antigen (PSA) test	1.1	1.3	4.0	1.3	0.2	1.5	0.4	1.3	0.6	1.4	1.0	0.1	2.0	-1.2
Commuting to job workplace: Cycle	1.1	1.4	3.7	-1.2	-0.1	-0.9	-1.3	-1.1	-1.0	-1.2	-0.7	-1.9	-1.8	0.5
Lung FVC	1.0	5.2	12.1	2.7	2.3	0.9	3.5	0.8	3.0	1.5	3.0	1.6	2.8	-0.0
Frequency of depressed mood in last 2 weeks	1.0	1.3	4.4	0.0	-2.1	0.9	-1.3	1.5	-1.2	1.1	-0.9	-0.9	-1.0	-0.2
Eye problems/disorders: Diabetes related eye disease	1.0	1.1	2.9	-1.6	-1.7	-0.3	-1.5	-0.4	-0.5	-0.7	-1.5	0.9	-0.5	0.6
Townsend deprivation index at recruitment	1.0	1.4	6.0	-0.9	-0.3	-1.2	-1.2	-0.9	-1.2	-1.3	-0.7	-2.5	-0.8	0.0
Bilateral oophorectomy (both ovaries removed)	1.0	1.2	2.6	-1.6	-0.0	-1.6	-0.9	-1.3	-0.8	-1.2	-0.8	-1.0	-0.9	1.0
Heel bone mineral density (BMD) T-score, automated (left)	1.0	2.3	6.1	0.4	2.5	1.2	-1.7	1.2	-1.6	1.0	-1.1	-1.7	0.5	-2.3
Neuroticism score	1.0	2.1	6.1	0.4	0.4	2.1	-2.1	2.5	-1.4	1.7	-1.3	-0.9	-0.7	-0.5
Medication: Lansoprazole	1.0	1.2	5.1	0.4	-0.1	1.1	-1.3	0.6	0.8	0.8	-0.5	0.7	2.2	-1.5
Overall health rating	1.0	2.1	7.4	-1.1	0.5	0.3	-2.7	0.1	-2.5	-0.5	-1.8	-1.8	-1.0	-0.7
Leg pain on walking	1.0	1.2	3.5	1.2	0.1	1.2	-0.2	1.6	0.3	1.9	0.8	1.5	0.2	1.3
Supplements: Vitamin C	1.0	1.1	2.4	-1.5	-1.4	-1.0	-0.1	-1.2	-0.3	-1.5	-1.1	0.5	-1.1	0.9
Guilty feelings	1.0	1.4	5.4	0.8	0.5	2.3	-0.8	2.2	-0.0	1.9	-0.4	0.2	0.3	-0.3
Fractured/broken bones in last 5 years	1.0	1.3	5.1	-0.5	-2.3	0.7	-1.1	0.5	-0.9	0.5	-1.1	0.8	-1.2	1.5
Alzheimer’s Disease (including proxy)	0.9	1.3	3.5	1.2	-0.1	0.9	1.1	1.0	0.9	1.2	1.0	1.9	1.8	0.4
Ulcerative Colitis (UC)	0.9	1.6	3.8	1.8	-0.0	1.2	1.5	1.1	2.0	1.0	1.8	0.9	0.1	1.0
Ulcerative Colitis	0.9	1.3	3.0	1.7	-0.2	1.2	1.4	1.0	1.7	1.1	1.6	0.7	0.3	-0.1
Alcohol usually taken with meals	0.9	1.5	4.8	0.6	-1.6	0.7	1.3	0.5	1.8	0.5	1.1	1.1	2.2	0.3
Heel bone mineral density (BMD) T-score, automated (right)	0.9	2.2	5.2	0.1	2.1	1.0	-2.0	1.1	-1.6	1.0	-1.1	-2.3	-0.4	-1.8
Lung cancer (father)	0.9	1.1	3.2	1.0	-0.0	1.8	0.3	1.8	0.3	1.4	0.3	1.0	1.2	-0.1
Pulse wave peak to peak time	0.9	1.1	3.1	-0.6	1.3	0.8	-1.5	0.7	-1.8	0.5	-1.1	-1.2	-0.9	0.2
Suffer from ‘nerves’	0.9	1.4	3.5	1.7	0.8	1.7	-0.4	1.9	0.5	1.5	0.7	0.8	0.5	0.9
Qualifications: NVQ or HND or HNC or equivalent	0.9	1.1	3.2	-0.6	1.6	-1.8	0.2	-1.7	0.3	-1.6	0.3	-0.6	-0.2	0.1
Forced expiratory volume in 1-second (FEV1), predicted	0.9	1.9	8.2	-0.7	1.2	-0.4	-1.1	-0.1	-1.9	-0.5	-1.8	-0.9	-2.9	1.1
Pain type(s) experienced in last month: Hip pain	0.9	1.1	3.2	-0.3	-0.3	0.6	-1.4	0.9	-1.5	0.7	-1.0	-1.8	-1.3	0.7
Diastolic blood pressure, automated reading	0.9	2.9	9.2	-2.0	-0.6	-2.4	-1.1	-2.8	-0.7	-3.0	-1.6	0.0	-0.7	-0.4
Schizophrenia (2018)	0.8	1.6	3.7	-1.4	-0.6	-1.7	-0.5	-1.6	-0.8	-1.9	-1.0	-0.8	-1.9	0.1
Crohns Disease (2012)	0.8	1.3	3.3	1.1	-0.2	1.8	0.3	1.6	0.3	1.6	0.0	0.8	1.1	-1.5
Type 2 Diabetes (T2D) (2012)	0.8	0.9	2.4	1.2	0.8	1.0	0.8	0.6	1.2	0.9	1.2	1.6	0.3	0.5
Severe depression (siblings)	0.8	0.9	2.2	-0.4	1.3	1.0	-1.5	0.9	-1.4	0.7	-1.1	0.2	-0.6	0.5
High blood pressure (mother)	0.8	1.1	2.8	0.8	0.8	1.5	-1.1	1.2	-0.4	1.7	-0.3	0.7	-1.5	0.7
Had other major operations	0.8	0.9	2.8	-0.7	-1.7	0.5	-1.3	0.3	-1.0	0.6	-1.4	0.6	-1.2	0.1
Number of live births	0.8	1.1	9.2	-0.4	3.0	-0.4	-0.9	-0.6	-0.4	-0.2	-0.7	-0.6	-0.7	0.1
Noisy workplace	0.8	1.0	2.5	-0.4	0.3	-0.5	-1.5	-0.3	-1.6	-0.7	-1.4	-1.5	-1.1	0.0
Pulse wave Arterial Stiffness index	0.8	0.9	2.6	0.4	-1.4	-0.8	1.3	-0.8	1.6	-0.4	0.9	1.0	0.6	-0.0
Length of working week for main job	0.8	0.8	4.6	0.8	-2.1	0.5	0.7	0.5	0.6	0.8	0.7	1.0	0.5	0.4
Loud music exposure frequency	0.8	0.8	2.1	0.6	-0.0	1.3	-0.9	1.2	-1.1	1.5	-0.7	-0.3	-0.4	0.8
Shortness of breath walking on level ground	0.8	1.0	4.0	0.5	-0.4	0.4	0.1	1.0	0.3	1.3	1.0	0.7	-2.0	1.6
Eye problems/disorders: None of the above	0.8	0.9	4.9	-0.4	2.2	-0.9	0.7	-1.0	0.1	-0.8	-0.1	-1.2	-0.1	-0.9
Medication: Allopurinol	0.8	1.0	2.9	1.4	-1.1	0.4	0.3	0.4	1.7	0.5	1.3	1.1	1.4	-0.1
Illness, injury, bereavement, stress in last 2 years	0.8	1.0	3.2	0.1	0.4	-1.5	0.3	-1.6	-0.0	-1.4	0.3	-0.9	-0.2	-1.8
Illnesses of father: High blood pressure	0.8	1.1	2.7	-1.1	-0.8	0.8	-1.3	0.8	-1.4	0.5	-1.6	0.4	-1.2	0.3
Myopia	0.8	1.2	5.7	-1.0	-0.1	-0.4	-0.5	-0.7	-1.1	-0.9	-0.8	0.2	-2.4	1.5
Cholesterol lowering medication	0.8	1.2	6.7	-0.0	2.6	-0.0	0.4	-0.3	1.5	-0.5	0.4	0.8	1.2	-1.1
Irritable Bowel Disease (IBD)	0.7	1.8	3.1	1.1	0.4	1.8	1.4	1.7	1.7	1.7	1.6	1.0	1.0	-0.3
HDL Cholesterol	0.7	1.1	3.2	-0.7	0.2	-0.0	-1.5	0.2	-1.5	-0.1	-1.3	-1.8	-0.9	-1.3
Waist Hip Ratio (WHR)	0.7	3.0	13.5	-1.8	3.7	0.5	-2.5	-0.0	-0.2	-1.2	-1.9	-0.1	-2.1	0.2
Respiratory disease	0.7	1.6	6.1	-0.5	-1.1	0.0	-0.6	0.3	-0.8	0.3	-1.0	1.4	-2.5	2.4
Medication: Metformin	0.7	1.0	3.6	-0.5	0.3	-0.5	-1.9	-0.7	-1.0	-1.2	-1.1	-0.9	-0.8	0.8
High blood pressure	0.7	1.8	7.2	1.9	1.6	0.1	0.9	0.2	2.7	0.2	1.6	1.6	1.0	0.1
Medication: Atenolol	0.7	0.8	2.7	-0.2	0.9	-1.1	-0.4	-1.3	0.4	-1.6	-0.0	0.5	0.8	-1.1
Heart attack	0.7	0.9	1.8	0.6	1.2	-0.2	0.9	-0.7	1.0	-0.6	1.4	1.3	0.9	-0.9
Falls in the last year	0.7	0.9	2.8	0.9	-1.7	0.9	0.7	1.2	0.4	1.4	0.8	0.7	0.3	0.5
Illnesses of mother	0.7	0.9	3.6	-0.9	-0.8	-0.4	-0.4	-0.3	-1.3	-0.6	-1.1	-1.9	-0.9	-0.1
Tense / ‘highly strung’	0.7	1.2	4.4	2.1	0.6	1.3	0.4	1.9	0.1	1.3	0.4	1.0	0.3	-0.3
Birth weight of first child	0.7	1.3	7.2	-1.0	-0.4	0.3	0.2	0.4	-2.1	0.7	-0.8	-0.7	0.3	-2.7
Peak expiratory flow (PEF)	0.7	1.6	5.0	-2.2	1.4	-1.6	-0.8	-1.5	-0.9	-1.6	-1.1	-0.6	-1.0	0.0
Headache pain in last month	0.7	1.2	2.7	-1.6	0.7	-0.9	-1.0	-0.9	-0.9	-1.2	-1.2	-1.7	-0.2	-0.8
Worry too long after embarrassment	0.7	1.1	4.3	0.8	0.4	1.7	-0.1	2.1	-0.3	1.8	0.6	0.2	-0.7	0.0
Neck or shoulder pain in last month	0.7	1.0	2.9	-0.7	-0.3	0.5	-1.3	0.6	-1.7	0.2	-1.6	-1.0	-1.2	0.6
Medication: Seretide 50 evohaler	0.7	0.8	3.6	0.6	-1.9	0.9	0.1	1.1	0.3	0.9	0.1	1.0	-0.2	1.1
Comparative height size at age 10	0.7	3.6	12.7	-2.5	0.2	-1.6	-0.3	-1.4	-1.0	-1.1	-1.8	0.6	-3.6	3.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.7	0.8	1.7	-1.2	-1.0	-1.2	-0.3	-1.2	0.0	-1.3	-0.5	-0.6	1.1	0.4
Illnesses of father: Heart disease	0.7	1.0	3.2	-1.8	-0.1	-0.5	-1.0	-0.8	-1.3	-1.2	-1.3	-0.6	0.1	0.4
Osteoarthritis (self-reported)	0.7	0.9	2.3	0.9	0.7	-0.7	1.5	-0.5	1.1	-0.2	1.5	-1.0	0.7	-1.0
Age started oral contraceptive pill	0.7	0.9	2.8	0.4	0.3	-0.3	1.1	-0.8	1.4	-0.5	0.8	0.9	1.7	-1.3
Ever depressed for a whole week	0.7	0.9	2.6	-0.9	-0.8	0.6	-1.3	1.0	-0.6	0.5	-0.9	-0.4	-1.6	1.1
Vascular/heart problems diagnosed by doctor	0.7	1.9	6.6	-1.8	-1.4	-0.0	-1.0	-0.1	-2.6	-0.1	-1.7	-1.9	-0.5	-0.9
Heart attack/myocardial infarction (self-reported)	0.7	0.9	2.0	0.6	1.4	-0.1	0.8	-0.6	0.8	-0.6	1.1	1.3	1.1	-1.2
Depressed Affect (Nagel 2018)	0.6	1.3	3.7	-0.3	-1.9	1.2	-1.6	1.4	-0.7	0.7	-1.2	-1.3	-0.1	-0.6
Crohns Disease (2017)	0.6	1.4	3.1	0.0	1.1	1.8	0.2	1.7	0.5	1.8	0.7	0.6	1.1	-1.5
Bipolar Disorder (2011)	0.6	0.6	2.2	0.1	1.2	1.5	0.0	1.4	-0.6	0.9	0.0	0.0	0.0	0.0
Neuroticism (2016)	0.6	0.9	2.0	0.2	-1.4	0.9	-1.2	1.1	-0.6	1.3	-0.8	-0.6	-0.5	-0.7
Triglycerides	0.6	0.9	2.9	1.4	0.8	0.2	1.0	0.0	1.7	0.1	1.5	0.3	0.9	0.8
Blood Red Count	0.6	5.7	17.7	-0.9	1.7	-4.0	-1.5	-4.2	-0.3	-4.1	-0.7	-0.8	-2.0	-1.2
Diabetes (mother)	0.6	0.7	2.8	0.5	1.2	0.8	-0.1	0.9	0.1	0.8	0.1	-0.7	1.0	-1.7
Frequency of tenseness / restlessness in last 2 weeks	0.6	0.9	2.8	0.2	-1.7	1.1	-1.5	1.5	-0.8	0.8	-0.7	0.2	-0.1	0.0
Financial difficulties in last 2 years	0.6	0.8	2.5	0.0	1.6	0.9	-0.7	1.0	-0.5	0.6	-1.2	-0.1	-1.3	0.4
Hayfever/allergic rhinitis (self-reported)	0.6	0.8	2.5	-0.7	-0.5	-1.1	-0.5	-0.9	-1.1	-1.1	-0.5	-0.8	-1.6	0.4
Time employed in main current job	0.6	0.7	2.3	0.9	1.5	0.3	1.0	0.2	0.8	0.1	0.7	0.6	0.4	-1.3
Medication: Cholesterol lowering	0.6	1.0	3.1	0.8	0.7	0.2	0.5	-0.1	1.4	-0.2	0.9	1.8	1.7	0.7
Prospective memory result	0.6	0.8	2.4	1.6	-0.7	0.8	0.3	0.9	0.9	1.3	0.5	0.8	0.4	0.8
Migraine (self-reported)	0.6	0.8	2.9	-1.1	-0.6	-1.7	-0.1	-1.4	-0.7	-1.1	-0.1	-0.2	-0.5	-0.0
Commuting to job workplace: Car/motor vehicle	0.6	0.7	2.3	0.8	0.8	1.2	-0.2	1.0	0.1	0.9	-0.6	0.1	-0.1	-1.5
Average weekly red wine intake	0.6	1.0	2.3	1.1	-0.6	0.6	1.3	0.4	0.9	0.9	1.5	1.1	1.3	0.3
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.6	0.8	3.3	-0.9	0.3	-0.1	-1.4	-0.4	-1.8	0.1	-0.9	-1.0	-0.3	0.0
Mineral and other dietary supplements	0.6	0.8	3.8	-0.6	-0.1	0.3	-1.4	0.3	-1.4	0.4	-0.8	-0.4	-1.9	0.3
Average weekly champagne plus white wine intake	0.6	0.8	2.1	0.9	-1.3	1.3	-0.1	1.2	-0.6	1.4	-0.3	-0.3	0.3	-0.3
Wears glasses or contact lenses	0.6	0.7	3.4	-0.4	-1.8	-0.5	0.6	-0.5	0.3	-0.3	0.6	0.2	0.4	1.4
Financial situation satisfaction	0.6	0.8	2.5	1.2	1.6	1.0	-0.4	0.8	-0.6	1.0	-0.0	-0.7	-0.4	-0.9
Medication: Bendroflumethiazide	0.6	1.0	2.1	-0.1	1.0	-1.2	1.0	-1.4	1.0	-1.5	0.8	0.4	0.3	-1.1
Medication: Lisinopril	0.6	0.8	2.0	0.7	-0.9	0.6	0.8	0.3	1.1	0.8	1.3	1.4	0.4	-0.3
Irritability	0.6	0.9	2.2	1.5	-1.0	1.1	0.5	1.4	0.4	1.3	0.6	1.0	-0.2	-0.4
Ovarian Cancer	0.5	0.7	1.5	1.1	-0.8	0.6	-1.2	1.0	-1.1	0.4	-0.5	-1.0	-0.4	0.1
LDL Cholesterol	0.5	0.9	2.3	-0.7	1.0	-0.5	-1.3	-0.4	-0.8	-0.8	-1.5	-0.5	0.1	1.4
Lupus	0.5	0.8	4.5	0.2	0.7	0.6	-0.1	0.9	-0.5	0.7	-0.6	-0.2	-2.1	1.0
Schizophrenia (2014)	0.5	1.2	3.2	-1.3	-0.2	-1.5	-0.3	-1.3	-0.5	-1.8	-0.5	-0.6	-1.8	-0.4
Height	0.5	8.9	22.4	-4.7	1.5	-2.5	-2.8	-3.1	-2.8	-3.4	-3.9	-1.3	-3.6	0.1
Hand grip strength (right)	0.5	1.3	6.2	0.1	2.5	-0.3	1.7	-0.2	1.3	-0.1	0.7	1.4	-0.9	0.6
Qualifications: CSEs or equivalent	0.5	0.6	1.6	0.4	1.3	0.8	-0.0	0.9	0.9	0.4	0.1	-0.8	-1.3	0.1
Serious illness, injury or assault to yourself	0.5	0.6	2.5	-0.3	-0.1	1.1	-0.4	0.7	-0.3	0.7	-0.4	1.2	0.5	1.6
Hayfever, allergic rhinitis or eczema	0.5	1.0	4.2	0.8	1.1	0.9	0.4	0.9	0.4	0.8	1.0	0.9	-0.7	2.0
Medication: Levothyroxine sodium	0.5	0.8	3.1	0.2	1.1	-0.6	0.7	-0.1	1.8	-0.4	0.5	0.6	-0.5	1.7
Number of incorrect matches in round	0.5	0.8	2.5	1.6	-0.9	0.2	0.9	0.3	1.5	0.4	1.2	0.5	0.5	0.6
Medication: Simvastatin	0.5	0.7	4.4	-0.4	-0.3	0.2	-0.3	-0.0	1.0	-0.1	0.1	1.1	2.1	-0.7
Frequency of tiredness / lethargy in last 2 weeks	0.5	0.9	3.5	-0.0	0.3	0.6	-1.5	0.9	-0.9	0.4	-1.0	-0.8	-1.9	0.3
Medication: Ibuprofen (e.g. Nurofen)	0.5	0.6	2.1	0.6	-0.2	1.3	0.1	1.4	0.0	1.4	0.6	0.4	0.0	0.4
Forced expiratory volume in 1-second (FEV1), Best measure	0.5	1.5	13.2	-0.9	3.6	-0.3	0.1	-0.3	-0.4	-0.5	-0.8	-0.8	-0.8	0.1
Forced vital capacity (FVC), Best measure	0.5	1.7	14.2	0.2	3.8	-0.3	1.6	-0.3	0.7	0.0	0.5	0.5	0.3	0.9
Exposure to tobacco smoke outside home	0.5	0.7	3.0	0.1	0.8	-0.3	-1.0	0.2	-0.8	-0.3	-0.5	-0.8	-1.7	0.9
Mouth/teeth dental problems: Loose teeth	0.5	0.6	1.3	0.5	-0.1	0.2	1.1	0.3	1.1	0.7	0.9	1.1	-0.3	0.7
Medication for pain relief, constipation, heartburn	0.5	0.8	2.6	-1.0	-1.0	0.2	-1.4	0.1	-1.1	0.0	-1.6	-0.6	-0.8	0.3
Medication: Blood pressure	0.5	1.0	2.9	1.7	0.0	0.3	0.2	0.2	1.6	0.2	1.1	1.2	1.4	-0.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.5	0.6	2.0	-0.4	-1.3	0.4	-1.1	0.7	-1.4	0.3	-0.7	-0.3	-0.3	0.4
Chest pain or discomfort	0.5	0.8	3.9	0.6	0.7	0.8	-0.4	0.9	-0.2	1.1	0.2	0.2	-2.0	1.1
Hypertension (Self-reported)	0.5	1.5	5.7	1.7	1.8	0.1	0.7	0.1	2.4	0.0	1.3	1.3	0.8	-0.1
Mood swings	0.5	0.9	6.1	-0.4	-2.5	0.4	-1.3	0.7	-0.4	0.4	-0.9	-0.6	0.5	-0.1
Ever had bowel cancer screening	0.5	0.6	2.6	-0.2	-0.1	0.5	0.4	0.0	0.5	0.3	0.2	1.0	1.3	-1.6
Ever had stillbirth, spontaneous miscarriage or termination	0.5	0.5	1.2	0.9	0.3	1.1	-0.0	1.1	-0.4	0.9	-0.3	0.9	-0.3	0.7
Mouth/teeth dental problems: Mouth ulcers	0.5	0.8	2.3	-0.4	-1.5	0.3	-1.0	0.5	-1.5	0.4	-1.1	-0.2	-1.3	0.4
Asthma (self-reported)	0.5	0.9	4.4	-0.3	-0.9	-0.0	-0.4	0.4	-0.5	0.4	-0.2	1.2	-2.1	1.7
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.5	1.0	3.7	-1.2	0.9	1.2	-1.1	1.1	-0.4	0.9	-1.9	0.0	-0.4	0.6
Number of self-reported non-cancer illnesses	0.5	0.9	2.5	-0.7	0.1	-1.6	-0.0	-1.5	0.6	-1.6	-0.0	0.3	-0.4	1.1
Heart disease (siblings)	0.5	0.6	1.6	0.1	-0.7	0.7	-1.0	0.5	-1.2	0.3	-0.6	-1.3	0.1	-1.2
Intelligence (Savage-Jansen 2018)	0.4	1.3	3.3	-1.5	1.8	-0.6	-0.3	-0.7	-1.5	-0.2	-1.7	0.0	-1.7	0.1
Neuroticism (Nagel 2018)	0.4	0.9	3.3	1.1	-0.8	1.5	-0.4	1.8	0.2	1.2	0.2	-0.2	0.6	-0.5
Alzheimer’s Disease (in mother)	0.4	0.5	2.2	0.2	-0.1	0.2	0.6	0.5	0.7	0.5	0.0	1.2	1.5	-0.5
Reaction Time	0.4	0.8	1.5	-0.6	-0.8	-0.5	-1.1	-0.5	-1.2	-1.0	-1.2	-0.9	-1.2	0.5
Neuroticism	0.4	1.0	3.2	0.5	0.1	1.5	-1.2	1.8	-0.5	1.3	-0.5	-0.7	0.1	-0.9
Ever had hysterectomy (womb removed)	0.4	0.4	2.5	-0.2	0.3	0.1	-0.4	0.1	0.3	-0.1	-0.6	-0.0	1.6	-1.1
Average weekly fortified wine intake	0.4	0.5	2.0	0.3	-0.1	0.1	0.7	-0.1	0.7	-0.1	0.2	1.1	1.4	-0.9
Sitting height	0.4	3.1	9.4	-2.5	-1.4	-1.3	-1.1	-1.1	-1.5	-0.9	-2.3	0.5	-3.1	1.9
Allergy	0.4	0.9	4.4	-0.9	-0.7	-0.4	-0.6	-0.6	-0.4	-0.6	-1.1	-0.9	1.1	-2.1
Hair/balding pattern: Pattern 3	0.4	0.6	3.4	-0.4	1.9	-0.2	-0.0	-0.7	-0.4	-0.6	-0.5	-0.4	0.8	-1.0
Forced expiratory volume in 1-second (FEV1)	0.4	1.2	6.2	-1.6	2.5	-0.5	-0.6	-0.6	-0.6	-0.7	-1.2	-0.9	-0.8	0.2
Mouth/teeth dental problems: Dentures	0.4	0.7	1.3	-1.1	0.2	-0.7	-0.3	-0.6	-0.1	-0.9	-0.9	1.1	-1.1	0.9
Asthma	0.4	0.8	3.4	-0.1	-0.6	0.1	-0.4	0.4	-0.4	0.5	-0.1	1.4	-1.9	1.7
Depression (self-reported)	0.4	0.5	2.0	0.1	0.2	-0.7	1.0	-0.4	-0.0	-0.4	0.6	-0.6	1.1	-1.4
Standing height	0.4	4.2	16.6	-2.7	0.6	-1.0	-1.4	-1.0	-1.6	-0.9	-2.8	0.1	-4.1	2.5
Medication for cholesterol, blood pressure or diabetes	0.4	0.6	2.1	-1.2	0.1	-0.2	0.3	-0.0	-1.3	0.1	-0.6	-1.1	-1.4	-0.3
Hypothyroidism/myxoedema (self-reported)	0.4	0.7	2.0	-0.3	1.2	-1.1	0.7	-0.7	1.4	-0.9	0.4	0.3	-0.2	1.3
Arm fat-free mass (right)	0.4	2.2	11.8	-1.8	0.8	-1.2	-0.5	-0.6	-1.1	-0.7	-1.9	-0.5	-3.4	1.1
Number of children fathered	0.4	0.5	1.5	0.8	-1.2	0.3	-0.1	0.1	0.6	0.1	0.8	0.4	1.1	-0.7
Qualifications: College or University degree	0.4	1.2	8.9	-0.6	-3.0	-0.2	1.0	-0.1	0.2	0.0	0.4	1.5	0.5	0.7
Heart disease (mother)	0.4	0.5	1.3	-0.7	-0.5	-0.7	0.1	-0.9	0.0	-1.1	-0.4	0.6	0.6	1.1
Breast cancer (self-reported)	0.4	0.5	1.8	-0.1	0.4	1.1	-0.3	1.0	-1.3	0.9	-0.7	0.1	0.0	-0.5
Smoking status: Current	0.4	0.6	4.1	-0.1	-2.0	0.4	0.1	0.4	-0.3	0.3	0.2	-0.0	-0.2	1.3
Medication: Paracetamol	0.4	0.7	2.6	-0.7	-1.6	-0.5	-0.5	-0.5	-1.0	-1.0	-0.5	-1.0	0.0	-0.6
Arm fat-free mass (left)	0.4	1.9	8.9	-2.0	0.5	-1.3	-0.6	-0.8	-0.9	-0.8	-1.8	-0.3	-3.0	0.5
Number of operations (self-reported)	0.4	0.6	1.8	-0.2	-1.3	0.3	-0.8	0.3	-0.6	0.4	-0.7	-0.1	-1.2	1.1
Average weekly beer plus cider intake	0.4	0.6	2.1	-0.8	-0.3	-0.2	-0.5	-0.7	-1.5	-0.6	-0.7	-0.9	-0.7	-0.7
Risk taking	0.4	0.6	1.1	-0.8	-0.7	-0.4	-0.8	-0.2	-1.1	-0.8	-0.9	-0.9	-0.8	0.1
Arm predicted mass (left)	0.4	1.8	8.2	-2.0	0.3	-1.5	-0.4	-0.9	-0.8	-1.0	-1.5	-0.3	-2.9	0.7
Bipolar Disorder or Schizophrenia	0.3	0.8	4.0	-0.7	-0.9	0.3	-0.6	0.5	-0.6	-0.1	-0.9	0.6	-2.0	1.1
Verbal and Numeric Reasoning (VNR)	0.3	0.8	4.2	-0.3	2.0	-1.0	1.0	-0.9	0.9	-0.5	0.2	-0.2	0.2	-0.9
Breast Cancer	0.3	0.7	1.3	1.0	-0.2	0.7	0.9	0.9	1.0	1.1	1.0	0.3	0.7	-0.6
Age at First Birth	0.3	0.5	1.5	0.9	-0.2	-0.5	0.9	-0.2	0.5	0.0	1.2	-0.8	-0.6	0.5
Fasting Glucose	0.3	0.3	1.0	0.8	-0.6	0.2	1.0	0.4	0.3	0.4	0.6	0.7	0.6	0.0
Rheumatoid Arthritis	0.3	0.4	1.5	-0.2	-0.4	-0.4	0.6	-0.5	-0.3	-1.0	0.2	0.4	-1.2	-0.7
Blood Platelet Count	0.3	3.2	7.8	2.2	2.6	2.0	-0.6	2.8	-1.1	2.1	0.7	-2.1	-0.2	-0.8
Blood White Count	0.3	2.5	13.8	-1.0	3.7	-1.5	-0.7	-1.6	-0.5	-2.3	-0.2	-0.8	-1.0	0.1
Allergy or Eczema	0.3	0.9	5.3	0.3	1.4	-0.1	0.7	-0.2	0.1	-0.3	1.0	0.5	-0.4	2.3
Hypothyroidism (self reported)	0.3	0.6	2.5	-0.4	1.6	-1.0	-0.1	-0.7	0.5	-0.9	-0.3	-0.1	-0.7	0.9
Type 2 Diabetes (T2D) (2018)	0.3	0.5	2.6	0.1	-0.3	-0.7	-0.2	-0.8	0.6	-0.7	0.8	0.0	0.1	1.6
Hand grip strength (left)	0.3	0.9	4.3	0.2	2.1	-0.3	1.7	-0.0	1.3	-0.2	0.6	0.3	-0.6	-0.3
Average weekly spirits intake	0.3	0.4	1.6	0.5	-1.3	-0.5	-0.1	-0.3	0.9	-0.6	0.8	0.1	-0.2	0.8
Relative age of first facial hair	0.3	0.6	1.3	1.0	1.1	1.2	0.1	0.8	-0.2	0.8	0.5	0.6	1.1	0.5
Angina	0.3	0.5	1.6	0.4	-1.3	-0.2	0.3	-0.4	0.8	-0.5	1.1	0.1	0.8	-0.3
Pack years adult smoking proportion	0.3	0.4	1.4	0.9	-0.9	0.6	-0.5	0.6	0.1	0.2	0.0	1.2	-0.3	0.4
Maternal smoking around birth	0.3	0.4	1.5	0.2	0.2	1.1	-0.5	1.2	-0.2	0.9	-0.7	0.6	0.3	-0.1
Frequency of unenthusiasm / disinterest in last 2 weeks	0.3	0.4	1.1	0.4	-0.4	0.1	-0.9	0.5	-0.7	-0.1	-0.2	-1.1	-0.9	-0.2
Taking other prescription medications	0.3	0.5	1.0	-0.8	0.9	-1.0	-1.0	-0.8	-0.4	-0.9	-0.8	-0.1	-0.1	0.4
Multivitamins +/- minerals	0.3	0.3	0.7	0.7	0.6	0.8	0.2	0.7	0.5	0.7	0.1	-0.1	0.8	-0.4
Chronic bronchitis/emphysema (father)	0.3	0.4	0.9	0.6	0.3	0.6	-0.7	0.7	-0.2	0.7	-0.4	-1.0	-0.6	-0.3
Impedance of leg (left)	0.3	1.4	4.8	-1.1	-2.1	0.7	-1.7	0.0	-0.8	-0.5	-2.2	0.3	-0.1	0.8
Hearing difficulty/problems with background noise	0.3	0.5	1.6	1.3	0.8	0.7	-0.4	0.8	-0.1	0.6	0.5	-0.4	-0.5	-1.1
Hair/balding pattern: Pattern 2	0.3	0.3	2.2	-0.4	-1.5	-0.4	0.2	-0.2	0.1	-0.6	-0.3	0.5	-0.2	0.5
Mouth/teeth dental problems	0.3	0.4	1.3	1.1	-0.1	0.7	0.5	0.5	0.6	0.7	0.8	-0.6	0.6	-0.2
Pain all over the body in last month	0.3	0.4	1.0	0.2	-1.0	0.3	0.6	0.1	0.9	-0.0	1.0	0.5	0.6	0.2
Illnesses of siblings	0.3	0.4	1.2	0.3	1.1	0.5	-0.1	0.6	-0.4	0.5	-0.3	0.8	-0.9	0.6
Trunk fat-free mass	0.3	1.9	12.2	-1.6	1.0	-0.8	-0.2	-0.3	-0.8	-0.3	-1.4	-0.3	-3.5	1.3
Trunk predicted mass	0.3	1.8	12.0	-1.5	0.9	-0.8	-0.2	-0.3	-0.8	-0.2	-1.4	-0.3	-3.5	1.2
Hair/balding pattern: Pattern 4	0.3	0.6	1.4	0.7	1.0	-0.3	1.2	-0.1	0.8	0.1	1.1	-0.8	0.1	-1.1
Chronic bronchitis/emphysema (mother)	0.3	0.4	1.2	-0.3	0.0	-0.4	-1.1	-0.4	-0.9	-0.2	-0.7	-1.0	-0.7	-0.0
High blood pressure (siblings)	0.3	0.5	1.2	0.0	-0.6	0.9	0.1	1.0	1.1	0.9	-0.3	0.5	0.7	0.2
Angina (self-reported)	0.3	0.4	1.3	0.5	-1.1	-0.3	0.3	-0.5	1.0	-0.6	1.1	0.2	0.7	-0.3
Arm predicted mass (right)	0.3	1.7	10.4	-1.5	0.9	-0.8	-0.2	-0.3	-0.9	-0.4	-1.7	-0.0	-3.2	0.9
Whole body fat-free mass	0.3	1.6	10.4	-1.3	1.2	-1.0	-0.1	-0.4	-0.7	-0.3	-1.1	-0.3	-3.2	0.9
Handedness (chirality/laterality): Left-handed	0.3	0.3	1.0	-1.0	-0.9	-0.7	0.1	-0.5	-0.1	-0.4	0.1	0.3	0.8	0.4
Long-standing illness, disability or infirmity	0.3	0.4	1.0	-0.9	-0.4	-1.0	-0.4	-0.9	0.0	-1.0	0.2	-0.0	-0.5	-0.5
Whole body water mass	0.3	1.5	9.6	-1.4	1.2	-1.1	-0.2	-0.5	-0.7	-0.4	-1.1	-0.3	-3.1	0.8
Hearing aid user	0.3	0.4	1.1	-0.8	-0.7	-0.7	-1.0	-0.6	-0.7	-0.4	-0.4	0.2	-0.5	-0.3
Basal cell carcinoma (self-reported)	0.3	0.3	1.7	-0.6	-1.3	-0.8	0.1	-0.4	-0.4	-0.4	0.3	-0.6	0.2	-0.3
Pack years of smoking	0.3	0.4	2.1	1.0	-0.5	0.7	-0.3	0.7	0.3	0.3	0.3	1.4	0.2	0.0
BMI	0.2	1.2	3.5	1.5	-1.0	0.4	1.9	0.9	1.2	1.1	1.4	1.1	0.2	-0.1
Systolic Blood Pressure	0.2	1.2	4.0	1.7	1.7	0.9	-0.3	0.8	2.0	0.5	0.8	0.5	0.5	-0.0
Cardiovascular Disease	0.2	0.5	2.7	1.0	1.6	-0.0	-0.1	0.1	1.1	-0.2	0.4	0.6	0.1	-0.1
Chronotype (morning person)	0.2	0.5	3.0	0.3	1.7	-0.3	-0.9	-0.4	-0.5	-0.6	0.3	-1.0	-0.2	0.1
Hair Pigment	0.2	4.3	13.4	-3.0	-2.5	-0.3	-1.9	-0.4	-3.7	-0.6	-3.3	-0.9	-1.1	1.3
Hearing difficulty/problems: Yes	0.2	0.3	1.2	0.3	-0.1	-0.2	0.8	-0.2	0.5	0.5	1.1	0.8	0.3	-0.2
Systolic blood pressure, automated reading	0.2	0.5	1.4	0.4	0.8	-0.6	-0.2	-0.8	1.2	-0.7	0.3	-0.2	1.0	-0.6
Medication for hormone replacement therapy	0.2	0.2	1.7	0.5	1.3	-0.2	0.1	-0.2	0.3	0.0	0.2	-0.4	0.1	-0.2
Impedance of leg (right)	0.2	1.1	3.6	-1.1	-1.9	0.7	-1.4	-0.1	-0.6	-0.5	-1.9	0.4	0.1	0.8
Trunk fat percentage	0.2	0.8	2.8	0.6	-0.3	-0.9	0.9	-0.7	1.7	-0.4	0.9	1.5	0.5	-0.6
Current tobacco smoking	0.2	0.4	2.6	-0.2	-1.6	0.2	0.1	0.2	-0.2	0.1	0.3	-0.1	-0.2	1.0
Age when periods started (menarche)	0.2	0.6	1.9	0.1	1.4	-0.2	-1.0	-0.6	0.2	-0.9	0.0	0.3	-1.0	-1.1
Stomach or abdominal pain in last month	0.2	0.3	1.0	-0.4	0.7	-0.2	-1.0	0.2	-0.3	0.1	-0.1	-1.0	-0.0	-0.1
Body mass index (BMI)	0.2	0.9	2.5	0.9	0.2	-0.7	1.6	-0.1	1.6	0.1	1.3	0.8	0.2	-1.1
Waist circumference	0.2	0.7	2.7	-1.3	0.2	-0.9	-0.6	-0.7	0.1	-0.9	-1.1	0.3	-1.6	-0.1
Nervous feelings	0.2	0.5	1.6	0.6	0.6	0.5	-0.5	0.7	-0.7	0.3	0.1	-1.2	1.1	-0.4
Forced vital capacity (FVC)	0.2	0.9	8.4	-0.3	2.9	-0.1	1.0	-0.1	0.5	0.2	0.1	0.1	-0.1	0.6
Diabetes (self-reported)	0.2	0.3	1.3	0.3	-0.5	-0.2	-0.7	-0.3	0.0	-0.5	-0.2	0.1	-0.8	1.1
Fluid intelligence score	0.2	0.4	1.7	-0.2	0.3	-0.8	1.3	-0.7	0.6	-0.5	0.5	-0.2	0.5	-0.7
Impedance of arm (right)	0.2	0.8	2.8	1.0	-0.6	0.9	0.1	0.4	1.0	0.7	1.1	1.1	1.7	0.5
Arm fat percentage (right)	0.2	1.0	3.1	1.2	-0.5	-0.5	1.2	-0.1	1.8	0.2	1.7	1.0	0.3	-0.7
Impedance of arm (left)	0.2	0.9	3.2	1.2	-0.4	0.8	0.2	0.2	0.9	0.6	1.0	1.3	1.8	0.7
Seen doctor (GP) for nerves, anxiety, tension or depression	0.2	0.2	0.8	-0.3	-0.7	0.1	-0.1	0.5	0.7	0.3	0.2	0.9	0.4	-0.2
Qualifications: O levels/GCSEs or equivalent	0.2	0.3	2.7	-1.7	0.2	-0.3	-0.3	-0.4	-0.1	-0.0	-0.6	0.0	-0.1	-0.6
Mouth/teeth dental problems: Bleeding gums	0.2	0.2	1.3	-0.1	0.1	0.1	-0.2	0.4	-0.6	0.4	-0.4	0.2	0.2	-1.2
Medication: Paracetamol	0.2	0.4	1.3	-0.2	-1.1	-0.2	-0.5	-0.2	-0.7	-0.6	-0.4	-1.1	0.3	-0.7
Birth weight	0.2	0.5	1.1	0.0	-0.3	0.9	0.9	0.6	-0.3	0.8	0.2	1.1	-0.8	0.8
Body fat percentage	0.2	0.7	2.3	0.6	-0.8	-0.7	0.9	-0.4	1.5	-0.2	0.7	1.4	0.3	-0.5
Wheeze or whistling in the chest in last year	0.2	0.4	2.7	-0.1	-0.8	-0.2	0.2	-0.0	-0.3	0.1	0.3	1.1	-0.2	1.6
Medication: Ibuprofen	0.2	0.3	0.7	-0.1	-0.2	0.4	-0.2	0.8	-0.8	0.6	0.1	0.2	-0.6	0.9
Alcohol intake frequency.	0.2	0.6	2.0	-0.7	0.6	-0.5	-1.4	-0.3	-0.7	-0.4	-0.7	-1.1	-0.9	0.2
Age at last live birth	0.2	0.3	1.5	0.1	0.8	-0.2	-0.5	-0.1	-0.5	-0.5	-0.4	-0.2	-1.2	0.3
Leg fat-free mass (right)	0.2	0.9	5.6	-0.5	1.5	-1.0	0.3	-0.3	-0.2	-0.1	-0.3	-0.1	-2.4	0.5
Arm fat percentage (left)	0.2	1.0	2.7	1.4	-0.3	-0.3	1.3	0.1	1.6	0.4	1.6	1.2	0.3	-0.6
Diabetes diagnosed by doctor	0.2	0.3	1.4	-0.1	0.5	-0.2	-1.2	-0.3	-0.6	-0.6	-0.5	-0.4	-0.5	0.7
Qualifications: nursing, teaching	0.2	0.3	1.3	-0.3	-1.2	0.1	0.2	0.0	-0.0	-0.0	0.2	-0.2	-1.0	0.6
Leg predicted mass (right)	0.2	0.8	5.7	-0.4	1.5	-0.8	0.3	-0.1	-0.2	0.0	-0.3	-0.0	-2.4	0.5
Basal metabolic rate	0.2	1.3	8.6	-1.3	1.0	-1.1	-0.1	-0.5	-0.6	-0.4	-1.0	-0.2	-2.9	0.6
Deep venous thrombosis (DVT) (self-reported)	0.2	0.2	0.7	0.0	-0.4	-0.1	-0.7	0.2	-0.6	0.2	-0.8	-0.4	-0.3	-0.6
Depression (Nagel 2018)	0.1	0.2	1.1	-0.1	-0.7	-0.0	-0.1	0.3	-0.3	-0.1	0.1	-1.1	0.0	-0.2
Worry (Nagel 2018)	0.1	0.3	1.1	1.0	0.6	0.3	-0.0	0.7	0.4	0.2	0.6	0.0	0.8	0.1
Primary Biliary Cirrhosis	0.1	0.1	0.6	0.1	0.4	-0.0	0.2	-0.3	0.1	-0.4	0.1	0.8	0.6	0.0
Blood Eosinophil Count	0.1	1.1	2.9	1.1	0.0	1.7	-0.4	1.5	0.7	1.4	0.5	1.4	-0.9	-0.6
Tanning	0.1	1.5	5.0	0.8	-0.6	-1.0	1.5	-1.0	2.2	-0.5	2.2	0.5	1.1	-0.7
Number of treatments/medications taken	0.1	0.2	0.7	0.3	0.7	-0.0	0.3	0.0	0.8	0.1	0.7	0.5	0.8	0.1
Vitamin and mineral supplements	0.1	0.1	0.6	-0.3	0.6	-0.3	-0.3	-0.2	-0.3	-0.1	0.0	-0.2	-0.8	0.2
Leg fat-free mass (left)	0.1	0.8	4.7	-0.5	1.5	-0.9	0.3	-0.3	-0.1	-0.1	-0.2	0.0	-2.2	0.4
Leg predicted mass (left)	0.1	0.8	4.7	-0.5	1.5	-0.9	0.3	-0.3	-0.1	-0.1	-0.2	0.0	-2.2	0.4
Trunk fat mass	0.1	0.4	1.2	0.1	0.1	-0.9	0.6	-0.6	1.1	-0.4	0.2	1.1	-0.8	-0.1
Qualifications: None of the above	0.1	0.2	0.7	0.8	0.1	0.1	-0.1	0.2	-0.2	0.4	0.1	0.1	-0.3	0.8
Weight	0.1	0.6	2.8	-0.4	0.5	-1.2	0.8	-0.6	0.6	-0.4	-0.1	0.7	-1.7	0.2
Hip circumference	0.1	0.5	1.9	0.0	-0.8	-1.4	1.2	-0.8	0.7	-0.3	0.7	0.5	0.1	0.1
Worrier / anxious feelings	0.1	0.2	0.7	0.0	-0.5	-0.1	-0.4	0.4	-0.1	0.1	0.4	-0.3	-0.5	0.8
Qualifications: A levels/AS levels or equivalent	0.1	0.3	1.0	-1.0	-0.1	-0.4	0.2	-0.5	-0.7	-0.5	-0.6	-0.2	-0.0	-0.5
Arm fat mass (right)	0.1	0.5	1.6	0.5	-0.2	-0.6	0.9	-0.1	1.3	0.1	0.9	1.0	-0.6	-0.3
Blood clot in the leg (DVT)	0.1	0.1	0.4	0.1	0.2	-0.4	-0.4	0.0	-0.3	-0.0	-0.5	-0.7	0.0	-0.6
Leg fat percentage (right)	0.1	0.4	1.2	0.2	-1.1	-0.5	0.7	-0.2	1.1	-0.3	0.2	0.8	0.1	-0.3
Age at first live birth	0.1	0.2	1.2	-0.5	-0.1	-0.1	0.3	-0.2	-0.1	-0.5	-0.0	0.5	-0.5	-1.1
Whole body fat mass	0.1	0.2	0.9	0.1	0.2	-0.6	0.3	-0.1	0.7	0.0	0.0	0.9	-0.9	-0.2
Leg fat mass (right)	0.1	0.2	1.1	0.1	-0.5	-0.2	0.3	0.3	0.5	0.2	-0.2	0.6	-1.1	-0.1
Back pain experienced in last month	0.1	0.1	0.4	0.1	0.1	-0.1	-0.0	0.1	0.6	-0.2	-0.1	0.6	0.4	-0.0
Arm fat mass (left)	0.1	0.4	1.1	0.5	0.1	-0.5	0.8	0.0	1.1	0.3	0.7	0.9	-0.7	-0.3
Leg fat percentage (left)	0.1	0.4	1.1	0.3	-1.0	-0.5	0.5	-0.2	1.0	-0.3	0.1	0.8	-0.0	-0.6
Unable to work because of sickness or disability	0.1	0.1	0.4	0.4	-0.6	-0.0	-0.5	-0.1	-0.2	-0.1	0.5	-0.1	-0.1	0.2
Impedance of whole body	0.1	0.5	1.9	-0.0	-1.4	0.5	-0.8	-0.1	0.2	-0.2	-0.5	0.8	1.1	0.8
Leg fat mass (left)	0.1	0.2	1.2	0.1	-0.4	-0.3	0.2	0.3	0.5	0.2	-0.3	0.6	-1.1	-0.3
Relative age voice broke	0.0	0.1	0.3	0.0	-0.0	-0.2	-0.2	-0.3	-0.3	-0.2	-0.0	-0.5	0.1	0.5
Mean time to correctly identify matches	0.0	0.1	0.5	0.2	-0.7	-0.0	-0.2	-0.0	-0.1	-0.3	-0.1	-0.1	0.1	0.1

Hub : Genes

NT5M

Models

Trait associations