Hub : Genes

NUBP2

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0510	0.0200	5.9e-04	0.036	0.023	0.020	0.023	0.028	2.9e-05	7.8e-04	1.5e-03	6.5e-04	2.3e-04
2	GTEx	Brain Cortex	0.2150	0.0840	5.5e-03	-0.004	NA	-0.009	NA	-0.006	4.4e-01	NA	6.5e-01	NA	4.9e-01
3	GTEx	Skin Sun Exposed Lower leg	0.0950	0.0390	7.9e-04	0.071	NA	0.032	NA	0.055	1.8e-06	NA	1.0e-03	NA	2.2e-05
4	GTEx	Thyroid	0.0980	0.0380	3.5e-03	0.089	NA	0.076	NA	0.081	2.4e-07	NA	1.8e-06	NA	8.7e-07
5	ROSMAP	Brain Pre-frontal Cortex	0.0957	0.0275	2.0e-09	0.048	0.066	0.075	0.067	0.077	6.7e-07	6.2e-09	6.1e-10	5.6e-09	4.3e-10
6	YFS	Blood	0.1050	0.0217	0.0e+00	0.116	0.118	0.141	0.149	0.070	9.2e-36	1.7e-36	9.9e-44	2.7e-46	7.2e-22
7	TCGA	Lung Adenocarcinoma	0.0427	0.0266	4.3e-03	0.030	0.014	0.019	NA	0.023	1.9e-04	7.5e-03	2.3e-03	NA	9.7e-04
8	TCGA	Ovarian Serous Cystadenocarcinoma	0.0460	0.0290	2.1e-03	0.025	0.031	0.025	NA	0.027	8.1e-03	3.2e-03	7.9e-03	NA	6.0e-03

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8
Bipolar Disorder (2018)	0.9	1.5	3.6	1.9	0.3	-1.3	1.2	1.3	1.3	-0.6	1.1
Bipolar Disorder or Schizophrenia	1.7	4.2	8.4	2.9	-0.9	-2.3	1.5	2.4	2.9	0.2	1.5
Depressed Affect (Nagel 2018)	2.3	4.8	8.5	2.9	-0.2	-1.4	2.6	2.8	2.1	0.6	2.9
Depression (Nagel 2018)	0.5	0.8	3.0	0.4	0.0	-1.4	0.6	0.7	1.7	0.4	-0.2
Intelligence (Savage-Jansen 2018)	1.0	3.1	9.5	-0.9	0.5	-2.4	-1.9	1.0	0.2	-3.1	-1.9
Neuroticism (Nagel 2018)	0.6	1.5	3.3	1.2	1.0	-0.7	1.8	1.5	1.0	-0.0	1.5
Schizophrenia (2018)	1.5	3.0	7.1	2.2	-1.4	-1.9	0.9	2.0	2.7	0.8	1.1
Schizophrenia vs Biploar Disorder	0.4	0.5	3.4	-0.6	-1.8	-0.2	-0.3	-0.2	-0.2	-0.2	-0.6
Worry (Nagel 2018)	0.2	0.4	2.4	-0.1	1.5	-0.3	0.5	0.6	0.1	-0.5	0.5
Alzheimer’s Disease (in mother)	0.8	1.0	3.9	0.6	-2.0	-0.8	0.0	0.4	0.0	-1.7	0.1
Alzheimer’s Disease (in father)	0.6	0.6	1.8	0.5	-0.9	0.4	0.9	0.3	0.6	0.8	1.3
Alzheimer’s Disease (including proxy)	0.7	1.0	7.0	0.0	-2.6	-0.3	-0.3	0.2	0.2	-0.7	0.5
Crohns Disease (2017)	0.5	1.1	3.5	-1.7	-0.5	0.4	-0.7	-1.1	-0.8	-0.4	-1.9
Irritable Bowel Disease (IBD)	0.5	1.1	2.8	-1.6	-0.5	0.7	-0.9	-1.1	-0.8	-0.7	-1.7
Ulcerative Colitis (UC)	0.2	0.3	1.0	-0.6	0.1	1.0	-0.1	-0.9	-0.4	0.1	-0.3
Major Depression (MDD)	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.2	-0.5
Reaction Time	0.7	1.4	3.4	-1.2	1.8	0.9	-0.0	-1.4	-1.2	-1.0	-1.1
Verbal and Numeric Reasoning (VNR)	1.0	2.4	8.0	0.6	-0.1	-2.8	-0.7	1.9	1.7	-1.8	-0.4
Breast Cancer	0.5	1.2	7.7	-0.3	-2.8	0.4	0.2	-0.7	-0.6	-0.7	0.1
Ovarian Cancer	2.3	3.1	6.1	2.5	0.1	-0.9	2.0	1.7	1.9	1.2	2.3
Prostate Cancer	3.5	5.0	8.8	2.9	0.5	-1.3	1.8	2.5	2.7	2.0	3.0
Age at First Birth	0.4	0.6	1.8	-0.9	1.3	-0.2	-1.0	0.0	-0.2	-0.1	-0.9
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Body Mass Index (BMI) (2010)	1.1	1.5	4.4	-2.1	-0.2	0.9	-0.9	-1.2	-0.4	1.9	-1.0
Coronary Artery Disease (CAD)	1.0	1.2	4.2	-0.1	0.9	-2.1	-1.5	0.8	1.1	-0.2	-0.5
Crohns Disease (2012)	0.2	0.3	0.9	-0.3	1.0	0.1	0.4	0.1	0.3	0.9	0.5
Mean Putamen Volume	2.2	2.5	5.1	2.2	-1.2	-1.9	-0.4	2.2	1.5	-0.6	1.4
Fasting Glucose	1.2	1.5	3.6	1.2	1.9	-1.0	1.3	1.0	1.0	-0.4	1.4
HbA1C	0.3	0.3	0.6	0.7	0.3	-0.8	0.3	0.8	0.8	-0.2	0.6
HDL Cholesterol	0.6	1.1	3.6	0.9	-0.2	-1.9	-0.4	0.8	1.2	-1.3	-0.4
LDL Cholesterol	0.9	1.4	4.0	1.5	-0.0	-0.2	1.7	1.3	0.5	0.2	2.0
Lupus	0.5	0.7	1.9	0.2	-1.4	-0.7	-0.2	-0.1	0.2	-1.1	-1.3
Neuroticism (2016)	0.4	0.5	2.4	0.7	0.5	0.0	1.5	0.7	0.4	0.3	0.7
Primary Biliary Cirrhosis	0.4	0.5	1.9	0.6	0.2	-0.4	0.3	0.4	1.1	1.4	0.6
Rheumatoid Arthritis	1.2	1.7	5.6	-1.8	0.7	0.3	-1.1	-1.5	-0.6	-0.2	-2.4
Schizophrenia (2014)	1.6	3.5	7.5	2.4	-1.3	-1.8	1.4	2.1	2.7	1.1	1.4
Triglycerides	1.7	2.8	7.8	1.4	-0.3	0.9	2.4	1.2	0.7	2.0	2.8
Type 2 Diabetes (T2D) (2012)	0.5	0.6	2.0	1.0	1.4	0.2	0.5	0.6	-0.2	-0.5	0.8
Ulcerative Colitis	0.3	0.4	2.3	-0.5	1.5	0.5	-0.7	-0.4	0.0	0.2	-0.1
Blood Eosinophil Count	0.1	1.0	4.0	-0.2	0.6	1.5	0.7	-0.7	-2.0	-0.4	0.5
Blood Platelet Count	0.3	3.5	9.6	-1.6	-0.0	2.0	-0.9	-2.0	-3.1	-2.5	-0.7
Blood Red Count	0.5	5.1	10.2	-3.1	-2.6	0.5	-2.3	-1.6	-1.8	-1.5	-3.2
Blood White Count	0.4	3.0	6.7	-1.9	-0.8	0.6	-1.8	-1.2	-2.6	-2.4	-1.6
Heel T-Score	0.3	2.5	6.0	2.2	1.0	-0.3	2.4	1.3	1.8	0.8	1.6
BMI	0.4	2.2	5.9	-0.0	-0.2	-1.6	-2.0	0.8	0.3	-2.0	-2.4
Height	0.4	8.6	20.3	-3.5	1.5	1.5	0.1	-3.0	-4.5	-3.4	-3.4
Waist Hip Ratio (WHR)	0.2	0.7	1.5	0.8	-0.5	0.9	1.2	0.1	-1.0	-0.5	1.0
Systolic Blood Pressure	1.4	7.1	32.6	-2.8	5.7	0.5	-2.1	-1.1	-1.8	-2.0	-1.7
Smoking Status	0.3	0.8	4.0	0.9	-2.0	-0.6	0.6	0.6	0.7	-0.2	-0.2
Allergy or Eczema	0.4	1.0	2.7	1.0	-0.2	-1.6	-0.5	1.5	0.8	-1.1	0.3
Cardiovascular Disease	1.9	6.2	12.5	-3.5	3.1	1.1	-1.5	-2.0	-2.5	-1.8	-3.3
Hypothyroidism (self reported)	1.2	2.9	5.4	-2.2	1.3	0.6	-1.4	-1.3	-2.1	-1.6	-2.3
Respiratory disease	0.7	1.6	3.1	1.3	0.5	-1.6	-1.1	1.8	0.6	-1.7	0.8
Type 2 Diabetes (T2D) (2018)	1.4	2.6	5.5	1.8	0.0	-2.3	1.0	2.1	2.2	-0.5	1.2
Lung FEV1/FVC ratio	0.7	3.4	6.6	-1.9	-1.0	0.6	-0.8	-1.9	-2.3	-2.4	-2.6
Lung FVC	0.6	3.3	6.1	-2.5	-1.7	2.1	-1.1	-2.4	-2.3	0.0	-0.7
Neuroticism	0.1	0.3	0.9	0.3	0.0	-0.3	1.0	0.9	0.4	-0.3	0.3
Chronotype (morning person)	1.1	2.6	7.6	1.3	1.2	-1.1	-0.3	1.0	2.8	2.5	1.3
Hair Pigment	0.1	2.1	8.1	-1.4	2.8	0.9	-1.4	-1.1	-0.9	0.2	-1.4
Tanning	0.2	2.9	7.9	1.3	-1.9	-0.6	1.4	0.8	2.5	2.8	1.0
Hand grip strength (left)	0.4	1.0	2.0	1.2	0.9	-1.3	0.3	1.4	0.7	-0.1	1.3
Number of treatments/medications taken	0.2	0.3	1.1	0.3	-0.5	-0.5	0.1	1.1	0.5	0.1	0.5
Average weekly spirits intake	0.7	0.9	2.2	-0.8	-1.5	0.2	-0.2	-0.7	-0.9	-1.1	-1.3
Sensitivity / hurt feelings	0.9	1.5	4.5	1.3	0.6	0.3	1.6	1.1	0.6	1.1	2.1
Frequency of depressed mood in last 2 weeks	0.5	0.6	2.3	0.2	0.1	-0.4	1.1	0.4	1.0	1.5	0.5
Hearing difficulty/problems: Yes	2.5	3.8	7.1	2.3	-0.1	-2.7	1.4	2.6	2.4	-1.7	0.8
Relative age of first facial hair	0.8	1.5	3.5	1.1	1.9	-1.7	0.5	1.1	1.8	-0.4	0.1
Other serious medical condition/disability diagnosed by doctor	0.8	1.1	2.8	-0.8	-0.3	-0.2	-1.5	-0.3	-0.7	-1.5	-1.7
Ever used hormone-replacement therapy (HRT)	0.3	0.4	1.5	0.3	-1.2	0.0	0.9	0.0	0.6	0.5	-0.2
Ever had hysterectomy (womb removed)	0.8	0.9	2.2	0.8	0.1	-0.3	0.8	1.0	1.2	1.5	1.0
Systolic blood pressure, automated reading	1.4	4.1	14.4	-2.6	3.8	0.5	-1.9	-1.3	-1.3	-1.2	-1.7
Eye problems/disorders: Diabetes related eye disease	1.7	1.9	4.5	-0.0	-0.9	-2.1	-2.0	0.8	1.4	-1.2	-1.3
Angina	0.1	0.1	0.5	-0.1	-0.0	-0.1	-0.3	0.3	0.2	0.7	-0.3
Medication for hormone replacement therapy	0.4	0.4	2.8	-0.3	-1.7	-0.1	-0.5	0.0	0.1	-0.1	-0.5
Vitamin and mineral supplements	0.3	0.4	1.3	-0.7	0.1	0.6	-0.2	-1.1	-0.7	0.4	-0.6
Supplements: Zinc	0.4	0.4	0.9	0.8	0.3	-0.3	0.9	0.7	0.6	0.2	0.8
Medication: Co-codamol	2.2	2.5	11.0	1.2	-3.3	-1.1	-0.6	1.4	0.2	-1.9	0.9
Medication: Metformin	1.3	1.9	6.0	0.8	-0.3	-2.4	-0.2	1.8	1.5	-1.5	-0.2
Diabetes (father)	3.2	4.0	11.4	2.5	-1.3	-0.8	1.4	2.3	1.8	1.2	3.4
Diabetes (mother)	1.3	1.7	4.8	1.7	0.9	0.4	1.8	0.6	0.3	1.1	2.2
Severe depression (siblings)	2.0	2.2	3.6	1.8	-0.2	-1.1	1.4	1.6	1.9	1.2	1.9
Pack years adult smoking proportion	1.9	2.9	11.0	1.0	-0.6	-0.6	1.4	1.2	2.0	3.3	1.6
Impedance of leg (right)	1.0	5.0	12.7	-1.6	-3.6	3.1	-0.1	-2.5	-2.9	-0.1	0.7
Leg fat-free mass (left)	0.3	1.4	3.9	-0.4	2.0	-1.1	-1.1	0.2	-0.4	-1.1	-1.8
Trunk fat percentage	0.2	0.7	3.6	0.9	-1.9	0.1	0.4	0.5	-0.3	-0.7	0.3
Hand grip strength (right)	0.1	0.4	1.6	0.3	1.3	-0.8	-0.2	0.6	0.1	-0.4	0.2
Townsend deprivation index at recruitment	2.1	2.9	6.9	-1.4	-2.6	2.3	-0.6	-2.0	-2.1	0.3	-0.5
Current tobacco smoking	0.3	0.5	2.8	0.5	-1.7	-0.4	0.3	0.3	0.9	0.3	-0.2
Average weekly fortified wine intake	1.9	2.2	4.2	-1.4	-1.3	0.5	-2.1	-1.0	-1.7	-1.9	-1.5
Maternal smoking around birth	0.1	0.1	0.3	0.1	-0.5	0.3	0.5	-0.1	0.3	0.5	-0.0
Fed-up feelings	1.5	2.7	4.7	2.1	-0.4	-0.9	1.9	1.9	1.9	1.0	2.2
Frequency of unenthusiasm / disinterest in last 2 weeks	0.6	0.8	2.0	0.6	-0.1	-0.8	0.5	0.9	1.4	1.4	0.4
Relative age voice broke	0.3	0.5	1.3	-0.4	1.1	0.8	0.4	-0.8	-0.7	-0.4	-0.6
Taking other prescription medications	0.2	0.3	1.1	-0.0	-1.1	0.0	-0.3	0.4	-0.4	-0.7	0.1
Age when periods started (menarche)	0.3	0.8	2.2	-0.6	-1.4	0.1	-1.5	-0.5	-0.5	-0.8	-0.8
Bilateral oophorectomy (both ovaries removed)	0.9	1.1	3.5	0.2	-1.2	1.4	1.1	-0.1	0.1	1.9	0.6
Heel bone mineral density (BMD) T-score, automated (left)	1.5	3.4	9.7	3.1	-0.0	-1.7	1.0	2.6	2.1	-0.4	1.7
Tinnitus: Yes, but not now, but have in the past	1.9	2.0	7.5	-1.2	1.1	0.3	-2.7	-0.8	-0.8	-0.4	-2.0
Qualifications: CSEs or equivalent	0.6	0.9	2.8	1.0	-0.5	1.2	1.0	-0.1	-0.8	0.2	1.7
Serious illness, injury or assault to yourself	3.2	3.9	7.6	2.5	-1.2	-1.7	1.4	2.5	2.1	0.8	2.8
High blood pressure	1.2	3.4	5.5	-2.4	2.2	0.8	-1.3	-1.3	-1.8	-2.1	-2.3
Hayfever, allergic rhinitis or eczema	0.8	1.7	5.5	0.9	0.1	-1.9	-1.2	1.5	0.4	-2.4	0.1
Multivitamins +/- minerals	0.9	1.1	2.2	0.8	1.2	-0.5	1.1	1.1	1.3	0.8	1.5
Stomach or abdominal pain in last month	2.1	2.6	6.3	-1.7	0.5	1.8	-0.9	-1.6	-2.5	-1.4	-1.7
Supplements: Glucosamine	1.3	1.6	3.1	1.4	-1.1	-1.7	-0.1	1.8	1.6	-0.7	0.9
Diverticular disease/diverticulitis (self-reported)	1.1	1.3	2.6	-1.4	0.4	1.3	0.9	-1.6	-1.6	-0.4	-0.8
Medication: Atenolol	0.7	0.9	2.0	-1.4	0.8	0.2	1.2	-0.7	-0.3	-0.6	-1.4
Medication: Levothyroxine sodium	0.3	0.4	1.1	-0.6	-0.0	0.2	-0.5	-0.3	-1.1	-1.1	-0.6
Sitting height	0.1	0.7	4.5	-0.3	2.1	-0.2	0.2	-0.0	-0.8	-0.2	0.5
Chronic bronchitis/emphysema (father)	0.6	0.7	2.4	-0.7	-0.8	-0.2	-1.5	0.2	0.4	0.9	-0.9
High blood pressure (mother)	0.3	0.5	2.6	0.4	1.6	-0.2	0.5	0.1	0.5	-0.4	-0.5
Body mass index (BMI)	0.1	0.5	1.5	0.3	-0.6	-0.8	-0.9	0.6	0.5	-0.2	-1.2
Impedance of leg (left)	1.1	5.5	11.7	-2.1	-3.1	3.4	0.3	-2.9	-3.1	-0.2	0.1
Leg predicted mass (left)	0.3	1.4	3.9	-0.4	2.0	-1.1	-1.2	0.3	-0.3	-1.0	-1.9
Trunk fat mass	0.1	0.5	1.6	0.0	-1.3	0.1	-0.5	0.0	-0.8	-0.9	-0.9
Waist circumference	0.4	1.5	3.5	-0.8	-0.7	0.3	-1.2	-0.5	-1.7	-1.7	-1.9
Number of incorrect matches in round	1.5	2.5	9.5	-0.8	1.2	-1.1	-1.6	-0.3	-0.7	-3.1	-2.1
Past tobacco smoking	0.1	0.2	0.6	-0.0	0.8	-0.0	0.2	0.2	0.7	0.5	0.5
Alcohol usually taken with meals	0.8	1.3	5.6	1.2	2.4	0.2	1.2	0.6	0.2	0.4	1.3
Nervous feelings	0.4	0.7	2.4	0.4	0.1	-0.3	0.9	1.1	0.8	0.7	1.6
Frequency of tenseness / restlessness in last 2 weeks	0.3	0.4	2.2	0.4	0.1	-0.1	1.5	0.7	0.4	0.5	0.4
Hearing difficulty/problems with background noise	1.5	2.4	5.2	1.5	-1.3	-2.2	0.3	2.3	1.7	-1.4	0.5
Hair/balding pattern: Pattern 2	0.5	0.6	1.5	-0.1	-1.1	1.0	0.7	-0.4	-0.5	1.2	0.4
Had menopause	0.5	0.7	2.9	0.6	0.9	0.5	1.7	0.1	0.1	0.3	1.0
Had other major operations	1.8	2.1	8.4	-0.1	-0.2	-1.8	-1.9	1.2	-0.2	-2.9	-0.7
Forced vital capacity (FVC)	0.8	3.2	7.0	-2.5	-0.5	1.5	-0.8	-2.3	-2.6	-1.3	-1.5
Heel bone mineral density (BMD) T-score, automated (right)	0.7	1.7	3.9	1.9	-0.5	-1.5	0.1	2.0	1.5	-0.5	0.9
Ever unenthusiastic/disinterested for a whole week	0.8	0.9	2.2	-1.3	-1.5	0.2	-1.0	-0.7	-0.5	-0.2	-1.3
Qualifications: None of the above	1.7	3.6	9.9	0.9	-3.1	1.2	1.8	-0.0	0.8	2.9	2.0
Financial difficulties in last 2 years	0.3	0.4	1.5	0.5	-1.2	0.1	0.0	0.5	-0.1	0.5	1.0
Mouth/teeth dental problems	0.5	0.7	2.1	0.2	0.9	1.4	-0.3	-1.1	-0.9	0.6	0.6
Heart attack	0.7	0.8	2.8	0.1	-0.0	0.0	1.7	0.2	0.7	1.6	0.9
Allergy	0.3	0.6	2.9	-0.4	-0.1	0.8	0.8	-0.7	0.4	1.7	-0.1
Pain all over the body in last month	0.9	1.0	2.0	1.4	0.7	-0.3	1.4	0.8	1.1	0.7	1.0
Diabetes (self-reported)	0.8	1.3	2.1	1.4	0.1	-1.4	0.9	1.4	1.3	-0.6	1.2
Hayfever/allergic rhinitis (self-reported)	0.5	0.7	2.2	0.9	0.4	-0.8	-0.5	1.0	-0.0	-1.5	0.4
Medication: Ramipril	1.5	1.9	4.2	0.6	2.0	-2.0	0.1	1.8	1.1	-1.6	0.3
Medication: Simvastatin	0.8	1.1	2.0	-0.6	1.4	1.3	1.4	-1.2	-0.5	1.0	-0.2
Fluid intelligence score	1.5	3.1	9.7	0.2	1.9	-3.1	-0.8	1.8	2.0	-1.6	-0.7
Illnesses of siblings	1.8	2.5	4.9	2.0	1.5	-0.7	1.3	1.5	1.6	1.3	2.2
Neuroticism score	0.2	0.3	0.8	0.2	0.5	-0.3	0.9	0.9	0.3	-0.3	0.8
Weight	0.3	1.3	4.5	-0.9	0.2	-0.3	-1.4	-0.4	-1.1	-1.2	-2.1
Impedance of arm (right)	0.7	3.2	13.3	2.1	-0.2	0.8	2.5	0.8	-0.2	0.1	3.6
Arm fat percentage (right)	0.2	0.8	2.3	1.5	-1.0	-0.5	0.3	1.2	0.6	-0.4	0.5
Trunk fat-free mass	0.7	4.3	12.5	-2.6	1.4	0.1	-2.3	-1.6	-2.0	-1.4	-3.5
Hip circumference	0.6	2.4	6.5	-1.1	-0.6	-0.9	-2.2	-0.1	-1.2	-2.2	-2.5
Time employed in main current job	0.3	0.4	1.9	0.3	0.7	0.0	1.4	0.0	0.4	0.6	0.1
Alcohol intake versus 10 years previously	1.8	2.7	6.3	-2.0	-0.7	1.8	-1.2	-2.1	-2.5	-0.6	-1.3
Father’s age at death	0.5	0.7	2.1	0.4	0.1	0.6	0.6	-0.0	-1.2	-1.4	1.0
Worrier / anxious feelings	0.7	1.3	5.3	-1.5	2.3	0.0	-0.6	-0.3	-0.9	-0.9	-0.6
Frequency of tiredness / lethargy in last 2 weeks	0.5	0.8	1.8	-1.0	-0.3	1.4	0.3	-1.2	-0.8	0.7	-0.9
Falls in the last year	0.3	0.4	1.8	0.1	-0.5	0.9	1.4	-0.4	-0.6	0.2	-0.1
Hair/balding pattern: Pattern 3	0.2	0.3	1.0	-0.8	-0.9	0.2	-0.2	-0.5	-0.2	0.2	-1.0
Number of live births	2.2	3.1	6.9	1.8	-1.1	-2.6	-0.1	2.6	2.2	-0.4	1.3
Forced expiratory volume in 1-second (FEV1)	1.1	3.7	7.9	-2.4	-0.5	1.4	-1.3	-2.3	-2.8	-1.7	-1.9
Pulse rate	1.3	2.1	5.7	-1.2	1.0	2.4	0.9	-1.8	-1.8	1.3	0.3
Happiness	0.7	0.8	2.4	-0.2	1.3	-1.3	-1.5	0.6	0.3	-0.7	-0.4
Noisy workplace	0.4	0.4	1.0	0.5	-1.0	-1.0	0.2	0.8	0.9	-0.0	0.1
Qualifications: A levels/AS levels or equivalent	0.7	1.5	4.0	0.0	2.0	-1.8	-1.2	1.2	0.9	-1.2	-0.2
Serious illness, injury or assault of a close relative in last 2 years	0.8	0.9	1.9	-0.8	-0.6	0.5	-1.1	-0.7	-1.1	-1.1	-1.4
Mouth/teeth dental problems: Dentures	1.4	2.3	5.2	1.7	-1.4	-0.7	2.3	1.6	1.7	1.0	1.4
Asthma	0.4	0.7	1.7	0.9	-0.1	-0.6	-0.5	1.1	-0.3	-1.3	1.1
Medication: Ibuprofen (e.g. Nurofen)	0.4	0.5	1.8	-0.4	-0.2	-0.1	-1.4	-0.0	-0.6	-0.8	-1.1
Medication: Cholesterol lowering	0.1	0.2	0.7	0.1	0.7	0.2	0.8	-0.3	-0.2	-0.1	0.2
Depression (self-reported)	0.6	0.7	1.7	1.1	0.2	-1.2	-0.3	0.9	1.3	0.1	0.7
Medication: Lansoprazole	1.1	1.3	2.5	1.6	-0.6	-0.4	1.1	1.6	1.1	0.5	1.4
Prospective memory result	0.8	1.0	2.9	0.8	-0.9	-0.0	1.7	0.5	0.9	1.2	1.1
Lung cancer (father)	1.6	1.9	3.6	-1.1	-1.9	1.9	0.8	-1.3	-1.2	1.6	-0.6
Illnesses of mother	0.2	0.3	1.2	-1.1	0.4	0.2	-0.5	-0.2	-0.4	0.2	-0.5
Forced expiratory volume in 1-second (FEV1), Best measure	1.5	4.9	10.6	-2.9	0.4	1.5	-1.6	-2.4	-3.3	-2.0	-2.2
Pulse wave Arterial Stiffness index	1.0	1.1	3.2	0.8	1.1	0.9	1.6	-0.1	-0.3	0.5	1.8
Impedance of arm (left)	0.7	3.2	13.2	2.2	-0.1	0.7	2.5	1.0	-0.1	-0.2	3.6
Arm fat mass (right)	0.1	0.5	1.1	0.7	-0.4	-0.9	-0.6	0.9	0.2	-1.0	-0.7
Trunk predicted mass	0.8	4.4	12.9	-2.6	1.4	0.0	-2.3	-1.5	-2.0	-1.5	-3.6
Standing height	0.5	4.8	12.7	-2.5	1.7	0.9	-1.1	-2.1	-3.6	-2.5	-2.1
Length of working week for main job	2.4	2.6	4.9	-1.9	1.0	0.8	-1.9	-1.6	-1.9	-1.1	-2.2
Exposure to tobacco smoke at home	1.0	1.1	2.3	-0.8	-1.4	-0.4	-1.5	0.0	-0.5	-0.9	-1.5
Breastfed as a baby	0.3	0.3	0.9	-0.5	-0.6	0.3	-0.2	-0.4	-0.8	-1.0	-0.5
Tense / ‘highly strung’	0.2	0.3	0.7	0.3	0.4	-0.8	0.5	0.6	0.7	-0.5	0.5
Seen doctor (GP) for nerves, anxiety, tension or depression	0.6	0.9	1.7	1.3	-0.6	-0.7	1.2	1.2	0.9	-0.3	1.0
Hair/balding pattern: Pattern 4	0.1	0.2	0.6	0.7	0.3	0.3	0.4	0.2	0.3	0.4	0.4
Birth weight of first child	2.8	5.1	14.0	2.0	-1.0	-3.7	0.2	3.2	2.9	-1.7	0.9
Peak expiratory flow (PEF)	0.5	1.2	4.8	-1.1	-0.8	-0.2	-2.2	-0.5	-0.7	-0.4	-1.4
Pulse wave reflection index	0.1	0.2	0.5	0.1	-0.4	0.4	0.4	-0.0	-0.5	-0.1	0.7
Ever highly irritable/argumentative for 2 days	0.3	0.4	1.3	0.9	-0.4	0.1	-0.6	0.5	0.3	0.6	1.1
Loud music exposure frequency	1.0	1.1	2.8	1.2	0.5	-0.9	0.8	1.0	1.7	1.1	0.8
Qualifications: O levels/GCSEs or equivalent	0.4	0.6	2.5	-0.3	1.6	-0.8	-0.7	0.5	-0.1	-1.0	-0.2
Mouth/teeth dental problems: Bleeding gums	0.4	0.5	1.8	-0.4	1.3	-0.9	0.4	0.5	0.4	-0.5	-0.8
Blood clot in the leg (DVT)	1.2	1.5	3.2	-1.6	-0.3	0.6	-0.2	-1.5	-1.5	-1.0	-1.8
Medication: Paracetamol	0.7	1.2	3.8	0.8	-1.9	0.3	1.6	0.7	0.3	0.9	1.1
Headache pain in last month	1.1	1.8	5.6	-0.3	-2.4	-0.9	-2.1	0.7	-0.2	-1.7	-0.6
Medication for cholesterol, blood pressure or diabetes	0.3	0.5	2.1	0.4	-1.5	-0.6	-0.7	0.5	0.7	0.2	-0.1
Glaucoma (self-reported)	0.5	0.6	2.8	0.1	1.7	0.3	0.8	-0.1	-0.4	-0.8	0.7
Gout (self-reported)	0.5	0.7	2.1	-1.0	-0.3	-0.2	-1.4	-0.6	-0.2	-0.3	-1.5
Hypothyroidism/myxoedema (self-reported)	0.9	1.8	4.0	-1.8	0.5	0.6	-0.9	-1.2	-1.6	-1.4	-2.0
Medication: Amlodipine	0.8	1.1	2.6	-1.6	0.8	0.0	-0.7	-0.9	-0.8	-1.2	-1.5
Medication: Ventolin 100micrograms inhaler	0.9	1.1	2.1	0.9	-1.2	-1.3	-1.0	1.4	0.6	-1.1	0.8
Birth weight	1.3	2.9	6.2	1.8	-0.4	-1.3	2.0	1.7	2.5	1.4	1.7
Chronic bronchitis/emphysema (mother)	1.3	1.5	2.3	1.5	-1.1	-0.6	1.2	1.4	1.4	1.1	1.3
High blood pressure (siblings)	1.8	2.7	6.7	-1.7	-1.5	-0.2	-2.2	-0.8	-1.1	-1.7	-2.6
Forced vital capacity (FVC), Best measure	0.9	3.5	7.4	-2.7	0.4	1.4	-1.1	-2.2	-2.7	-1.4	-1.7
Body fat percentage	0.2	0.7	4.3	0.6	-2.1	0.3	0.1	0.3	-0.4	-0.5	-0.1
Leg fat percentage (right)	0.6	2.3	8.8	-1.0	-3.0	1.4	-1.2	-1.2	-1.6	-0.2	-1.3
Arm fat-free mass (right)	0.8	4.3	12.7	-2.5	0.9	-0.3	-2.7	-1.2	-1.6	-1.6	-3.6
Exposure to tobacco smoke outside home	0.4	0.5	1.7	-1.0	-0.2	0.6	-0.6	-0.3	-0.2	1.3	-0.9
Comparative body size at age 10	1.4	4.0	12.1	-2.6	-0.2	-0.0	-3.1	-1.8	-0.4	0.2	-3.5
Number of full brothers	1.7	2.2	4.6	-1.4	-1.1	2.1	-1.6	-1.8	-1.9	0.3	-0.5
Worry too long after embarrassment	1.7	2.9	6.8	-2.4	0.9	0.4	-2.1	-1.5	-1.2	-1.4	-2.6
Seen a psychiatrist for nerves, anxiety, tension or depression	0.4	0.5	1.6	0.5	-1.0	-0.5	1.2	0.4	0.4	-0.8	0.3
Wheeze or whistling in the chest in last year	0.8	1.4	3.2	1.1	-1.6	-1.5	-0.7	1.8	1.0	-0.8	0.4
Number of children fathered	0.7	0.8	2.0	0.6	-1.0	-0.4	0.7	0.6	1.4	1.4	0.4
Reason for reducing amount of alcohol drunk: Health precaution	1.2	1.3	2.4	1.6	0.9	-1.0	1.0	1.5	1.0	-1.1	1.1
Age at first live birth	2.8	5.0	10.8	-1.9	3.1	-1.1	-2.5	-0.9	-0.6	-3.3	-2.8
Pulse wave peak to peak time	1.1	1.2	4.0	-0.9	-0.9	-0.9	-1.7	-0.0	0.1	-0.7	-2.0
Health satisfaction	0.2	0.3	0.7	-0.8	0.5	-0.8	-0.4	0.1	0.1	-0.3	-0.8
Shortness of breath walking on level ground	0.5	0.6	3.3	-0.3	-1.0	0.1	-0.2	0.1	0.7	1.8	0.5
Qualifications: College or University degree	1.0	3.1	7.5	0.6	2.7	-2.5	-1.5	1.5	0.8	-2.3	-0.4
Eye problems/disorders: None of the above	1.3	1.5	2.6	-1.6	1.2	1.0	-0.2	-1.6	-1.4	0.0	-1.4
Mouth/teeth dental problems: Loose teeth	1.2	1.4	3.1	-1.2	-1.8	1.1	0.1	-1.6	-0.6	1.3	-1.1
Emphysema/chronic bronchitis	1.0	1.1	4.4	-0.7	-2.1	-0.8	-0.7	0.4	0.7	0.9	-1.0
Medication for pain relief, constipation, heartburn	0.2	0.4	1.2	0.2	0.8	-0.9	-1.1	0.2	0.7	-0.3	0.0
Neck or shoulder pain in last month	0.6	0.9	2.2	-1.3	-0.1	0.5	-1.3	-0.8	-0.5	-0.1	-1.5
Medication: Blood pressure	0.3	0.6	3.1	-0.5	1.8	0.6	0.0	-0.3	-0.8	-0.5	0.0
Angina (self-reported)	0.1	0.1	0.5	0.2	0.2	-0.2	-0.1	0.5	0.4	0.7	0.0
Migraine (self-reported)	1.0	1.3	6.3	-0.4	0.3	1.3	1.1	-0.8	0.1	2.5	0.3
Medication: Ibuprofen	0.6	0.7	1.7	-0.1	0.6	-1.0	-1.3	0.8	0.0	-1.1	-1.0
Medication: Allopurinol	0.2	0.3	1.1	0.4	1.1	-0.5	-0.6	0.2	0.7	0.1	-0.1
Medication: Omeprazole	0.9	1.0	2.4	-1.0	-0.6	1.2	0.2	-1.2	-1.5	-0.8	-0.9
Medication: Seretide 50 evohaler	0.7	0.8	3.1	1.1	-1.8	-0.2	0.3	0.8	0.5	0.3	0.8
Mean time to correctly identify matches	1.4	2.7	4.8	-2.1	1.5	1.2	-0.1	-2.2	-1.6	-1.1	-2.1
Heart disease (mother)	0.5	0.6	1.3	0.4	-0.1	-1.1	-0.9	0.7	0.8	-0.9	-0.6
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.3	0.4	1.5	-0.2	0.5	-0.4	-0.7	-0.1	-0.4	-1.2	-0.5
Whole body fat mass	0.2	0.7	2.1	-0.1	-1.4	0.1	-0.7	-0.1	-0.8	-0.9	-1.1
Leg fat mass (right)	0.3	1.3	2.8	-0.8	-1.5	0.5	-1.4	-0.7	-1.3	-0.7	-1.7
Arm predicted mass (right)	0.8	4.1	13.7	-2.4	0.8	-0.6	-2.7	-1.1	-1.3	-1.5	-3.7
Pulse rate, automated reading	0.3	0.9	2.4	0.1	0.8	1.6	0.4	-0.7	-0.9	1.1	1.2
Alcohol intake frequency.	0.6	1.4	4.2	0.1	-0.1	1.6	1.3	-0.4	-0.1	2.0	1.5
Comparative height size at age 10	0.4	2.0	7.2	-1.3	0.1	1.6	0.2	-1.9	-2.7	-0.2	-0.8
Number of full sisters	1.0	1.2	3.6	1.5	-0.7	0.2	1.5	0.9	0.2	0.2	1.9
Suffer from ‘nerves’	0.2	0.4	2.1	-0.2	0.1	-0.4	0.1	0.6	-0.5	-1.5	0.3
Overall health rating	0.3	0.5	2.8	-0.4	-0.6	-0.6	-0.2	0.0	0.3	-0.7	-1.7
Chest pain or discomfort	0.4	0.6	1.8	-1.3	-0.7	0.5	-0.8	-0.5	-0.8	-0.2	-0.7
Had major operations	0.3	0.3	1.8	-0.1	-1.3	-0.1	0.7	-0.1	0.1	-0.3	0.1
Age at last live birth	3.1	4.5	12.6	-1.6	1.6	-1.5	-2.8	-0.2	-0.7	-3.6	-2.8
Family relationship satisfaction	0.8	1.0	2.8	-0.7	0.7	-1.1	-1.7	0.0	0.1	-1.2	-1.1
Leg pain on walking	0.2	0.2	0.6	-0.0	-0.7	0.1	-0.4	0.4	-0.1	0.8	0.4
Qualifications: NVQ or HND or HNC or equivalent	0.2	0.2	0.6	-0.1	-0.4	-0.6	-0.1	0.2	0.8	0.8	-0.2
Commuting to job workplace: Car/motor vehicle	0.8	0.9	1.5	1.2	-0.3	-1.2	-0.8	1.2	0.8	-1.1	0.2
Illness, injury, bereavement, stress in last 2 years	1.0	1.2	2.5	0.9	1.2	-1.6	-0.2	1.2	1.0	-1.5	0.2
Medication: Aspirin	0.5	0.6	2.2	0.3	0.3	0.9	1.5	-0.0	-0.4	0.8	1.1
Supplements: Vitamin C	0.9	1.1	2.9	0.4	-1.3	1.7	1.4	-0.7	-0.9	0.6	0.5
Knee pain experienced in last month	0.6	0.9	2.9	0.1	-1.7	-0.4	-1.3	0.2	-0.3	-0.7	-1.3
Hypertension (Self-reported)	2.0	5.7	10.2	-3.2	2.5	1.2	-1.8	-2.0	-2.4	-2.2	-3.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.7	1.9	7.6	1.2	-1.7	0.6	2.8	0.3	0.3	0.8	1.6
Illnesses of father: Heart disease	2.9	4.1	8.9	-3.0	1.1	1.7	-1.1	-2.6	-1.5	0.9	-2.9
Illnesses of siblings: Diabetes	0.6	0.8	4.2	0.4	-2.0	-0.1	1.1	0.2	0.1	-0.6	0.4
Smoking status: Previous	0.6	1.0	2.4	-0.6	-1.0	1.4	0.4	-1.2	-1.6	0.2	-0.5
Forced expiratory volume in 1-second (FEV1), predicted	0.5	1.0	2.1	-1.0	1.0	-0.0	-0.7	-0.8	-1.1	-1.5	-1.3
Whole body fat-free mass	0.5	3.0	9.4	-1.8	1.7	-0.5	-1.9	-0.9	-1.4	-1.4	-3.1
Leg fat-free mass (right)	0.3	1.6	5.6	-0.4	2.4	-1.2	-0.9	0.3	-0.1	-0.9	-1.9
Arm fat percentage (left)	0.2	0.8	2.3	1.5	-0.9	-0.7	0.1	1.4	0.6	-0.7	0.4
Average weekly red wine intake	0.4	0.6	1.9	0.9	0.6	-1.1	-0.0	0.8	1.4	-0.1	-0.1
Handedness (chirality/laterality): Left-handed	3.2	3.9	9.2	2.0	-0.2	-3.0	-1.1	3.0	2.5	-1.1	0.1
Mood swings	0.4	0.6	1.2	0.9	0.7	-0.2	1.1	1.0	0.6	-0.1	1.1
Loneliness, isolation	1.0	1.4	3.3	1.6	-0.8	-1.4	0.5	1.8	1.4	0.3	0.9
Long-standing illness, disability or infirmity	0.7	1.1	2.4	1.4	-0.8	-0.6	1.5	1.3	0.8	-0.5	0.8
Ever had bowel cancer screening	0.8	1.0	3.5	-0.8	-1.9	0.1	0.0	-0.9	-0.2	-0.7	-1.5
Diabetes diagnosed by doctor	1.3	2.2	3.8	1.7	0.4	-1.9	1.2	1.9	1.9	-0.4	1.3
Ever had stillbirth, spontaneous miscarriage or termination	0.5	0.5	1.7	-0.3	0.3	-0.7	-1.0	0.1	-0.3	-1.3	-0.8
Friendships satisfaction	0.9	1.1	3.8	-0.9	-0.0	-1.5	-1.9	0.4	0.0	-1.1	-1.1
Qualifications: nursing, teaching	1.1	1.7	4.5	-0.7	2.1	-1.0	-1.2	0.3	-0.4	-2.0	-1.3
Commuting to job workplace: Walk	0.7	0.7	3.8	-0.0	1.9	-0.9	-0.3	0.6	0.4	-0.7	-0.6
Eye problems/disorders: Cataract	0.8	1.0	3.6	0.2	-1.1	-1.2	-0.8	0.4	0.3	-1.9	-0.9
Mouth/teeth dental problems: Mouth ulcers	0.7	1.2	4.2	-0.9	-0.9	-0.9	-2.0	0.3	-0.3	-1.3	-0.8
Medication for cholesterol	0.5	0.7	1.6	1.3	0.6	-1.1	-0.4	0.9	0.7	-0.5	0.9
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.1	0.1	0.4	0.0	0.0	-0.1	-0.5	0.1	-0.2	-0.6	-0.4
Back pain experienced in last month	0.5	0.7	2.1	0.7	-1.4	-0.6	-1.0	0.9	0.1	-0.7	0.0
Mineral and other dietary supplements	0.8	1.0	2.2	-1.3	-0.2	0.5	-1.2	-1.1	-1.5	-0.8	-0.9
Breast cancer (self-reported)	0.2	0.3	1.4	0.3	-0.6	-0.5	-1.2	0.2	0.2	-0.1	-0.1
Asthma (self-reported)	0.3	0.6	2.3	0.6	-0.1	-0.4	-0.7	0.8	-0.6	-1.5	0.8
Osteoporosis (self-reported)	0.1	0.2	0.5	-0.0	0.2	0.0	-0.4	-0.1	0.4	0.7	-0.6
Osteoarthritis (self-reported)	0.4	0.5	1.9	0.1	-0.6	-0.1	-0.9	-0.0	-0.2	-1.4	-1.1
Medication: Aspirin	0.3	0.4	1.6	0.4	0.5	0.2	1.3	0.4	0.1	0.3	0.9
Medication: Gliclazide	1.1	1.2	3.6	0.7	-0.1	-1.9	0.6	1.5	1.5	-0.6	0.3
Illnesses of father: None of the above (group 1)	0.3	0.4	0.8	0.5	0.9	-0.4	-0.7	0.4	-0.3	-0.9	0.4
Smoking status: Current	0.4	0.7	3.1	0.5	-1.8	-0.7	-0.3	0.5	0.9	-0.3	-0.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	2.0	4.3	10.3	-3.2	-0.6	1.6	-1.6	-2.5	-2.5	-0.3	-2.4
Whole body water mass	0.5	3.0	9.2	-1.8	1.8	-0.5	-2.0	-0.8	-1.4	-1.4	-3.0
Leg predicted mass (right)	0.3	1.7	6.0	-0.4	2.5	-1.3	-0.9	0.4	-0.1	-1.0	-1.9
Arm fat mass (left)	0.1	0.5	0.9	0.5	-0.6	-0.7	-0.7	0.8	-0.0	-1.0	-0.9
Number of self-reported non-cancer illnesses	0.5	0.8	2.2	-0.5	1.1	-0.6	-0.9	0.1	-0.2	-1.5	-1.4
Average weekly champagne plus white wine intake	0.7	0.9	2.0	1.0	0.7	-1.4	0.4	1.2	0.4	-1.4	0.4
Miserableness	1.3	2.3	6.9	2.2	-0.4	0.2	2.1	1.3	0.2	0.2	2.6
Guilty feelings	0.3	0.5	1.1	-1.0	0.0	0.9	0.4	-0.5	-0.5	1.0	-0.7
Wears glasses or contact lenses	0.4	0.5	1.1	1.1	-0.1	-0.5	0.6	0.7	0.1	-0.9	0.9
Ever taken oral contraceptive pill	0.8	0.9	2.0	1.4	1.1	-0.1	1.3	0.7	0.5	0.1	1.1
Hearing aid user	0.4	0.4	1.1	-0.6	0.6	0.7	1.0	-0.7	-0.7	0.1	-0.0
Mother’s age at death	0.9	1.1	2.4	1.3	0.7	-1.4	-0.1	1.2	1.6	0.0	0.8
Financial situation satisfaction	0.1	0.1	0.3	-0.4	-0.2	-0.2	-0.5	0.3	0.0	0.5	-0.2
Tinnitus: Yes, now most or all of the time	0.8	1.0	4.6	0.2	-0.3	0.5	1.5	-0.2	0.7	2.1	0.4
Commuting to job workplace: Public transport	0.6	0.7	2.5	0.6	0.7	-0.8	-0.1	1.6	0.7	0.5	0.9
Eye problems/disorders: Glaucoma	1.0	1.2	3.7	0.8	1.9	0.7	1.5	0.1	-0.1	0.0	1.5
Medication: Blood pressure	1.2	2.2	4.2	-2.0	1.3	1.0	-0.5	-1.5	-1.6	-1.2	-2.1
Pain type(s) experienced in last month: Hip pain	0.9	1.1	2.7	0.8	-0.9	-1.6	-0.7	1.6	1.2	-0.3	0.5
Supplements: Fish oil (including cod liver oil)	0.4	0.5	1.4	0.7	-0.4	0.0	1.0	0.2	1.2	0.9	0.2
High cholesterol (Self-reported)	0.2	0.4	1.0	-1.0	-0.1	0.5	0.4	-0.9	-0.4	0.2	-1.0
Medication: Bendroflumethiazide	2.3	3.5	6.3	-2.2	1.0	2.4	-0.1	-2.5	-2.5	0.3	-2.1
Medication: Paracetamol	1.0	1.5	3.4	1.4	-1.5	-0.1	1.8	1.1	0.9	0.9	1.3
Medication: Lisinopril	1.4	1.9	4.4	-1.1	1.9	1.9	-0.4	-1.3	-2.1	-0.2	-0.7
Medication: Atorvastatin	0.1	0.1	0.3	0.2	0.2	-0.2	-0.0	0.5	0.5	0.5	0.5
Illnesses of father: High blood pressure	0.1	0.2	0.5	-0.2	0.6	-0.3	0.6	0.1	0.4	-0.1	-0.7
Alcohol drinker status: Never	0.5	0.6	1.4	-0.3	-1.2	1.2	0.7	-0.7	-0.6	0.4	0.0
Ever smoked	0.7	1.3	3.6	-0.6	0.6	-1.0	-1.4	-0.2	-0.4	-1.7	-1.9
Basal metabolic rate	0.5	2.6	8.2	-1.6	1.3	-0.5	-1.9	-0.7	-1.3	-1.4	-2.9
Leg fat percentage (left)	0.7	2.4	6.0	-1.4	-2.4	1.5	-1.0	-1.5	-1.7	-0.2	-1.8
Arm fat-free mass (left)	0.8	4.1	13.5	-2.5	0.6	-0.4	-2.6	-1.2	-1.5	-1.4	-3.7
Number of operations (self-reported)	0.4	0.7	1.3	0.7	-0.9	-1.1	-0.1	1.0	0.6	-1.1	0.1
Average weekly beer plus cider intake	0.1	0.1	0.6	0.3	0.8	-0.0	0.6	0.0	0.2	-0.2	-0.0
Irritability	0.9	1.5	2.8	1.0	1.1	-1.1	1.7	1.5	1.4	0.4	1.2
Risk taking	0.3	0.4	1.7	-0.0	-0.5	-0.2	0.5	-0.4	-0.3	-1.0	-1.3
Ever had prostate specific antigen (PSA) test	0.6	0.7	1.6	-0.4	-0.7	-1.0	-0.8	-0.4	0.1	-1.3	-1.1
Fractured/broken bones in last 5 years	0.2	0.2	0.5	-0.5	-0.3	0.3	0.1	-0.7	-0.1	0.6	-0.6
Age started oral contraceptive pill	0.6	0.8	2.5	0.3	0.1	-0.7	-0.3	0.7	1.4	1.6	0.5
Diastolic blood pressure, automated reading	0.6	1.8	5.0	-2.0	0.9	-0.3	-2.2	-0.6	-0.7	-1.3	-1.5
Ever depressed for a whole week	1.3	1.6	4.4	-1.3	-1.4	-0.7	-1.8	-0.6	-0.1	-0.9	-2.1
Unable to work because of sickness or disability	0.8	1.1	5.9	0.6	-2.4	0.2	0.6	0.0	0.6	1.2	0.3
Commuting to job workplace: Cycle	0.5	0.6	2.2	-0.0	0.3	-1.0	-1.0	0.4	-0.2	-1.5	-0.3
Myopia	0.3	0.5	1.0	-0.1	-0.9	-1.0	-0.5	0.5	0.1	-0.9	-0.8
Vascular/heart problems diagnosed by doctor	0.9	2.4	4.7	2.1	-2.2	-1.0	0.8	1.2	1.5	1.0	1.9
Cholesterol lowering medication	0.3	0.4	1.8	-0.1	0.6	0.2	0.6	0.1	0.8	1.3	-0.4
Medication: Omeprazole (e.g. Zanprol)	0.6	0.7	2.9	-0.1	-0.2	1.2	1.7	-0.5	-0.7	0.5	0.3
Pain experienced in last month	1.1	1.8	5.6	0.5	2.4	0.5	2.2	-0.2	0.4	1.3	1.2
Supplements: Calcium	2.2	2.4	5.5	2.1	0.1	-0.6	1.4	1.9	1.4	1.2	2.4
Basal cell carcinoma (self-reported)	0.1	0.1	0.6	0.0	0.8	-0.2	-0.1	0.0	0.3	-0.1	0.2
Heart attack/myocardial infarction (self-reported)	0.7	0.9	3.1	0.0	0.2	0.1	1.8	0.1	0.7	1.8	0.8
Deep venous thrombosis (DVT) (self-reported)	1.2	1.6	3.1	-1.7	-0.1	0.8	-0.0	-1.6	-1.6	-0.8	-1.8
Heart disease (siblings)	2.1	2.6	6.1	-2.5	-0.4	1.3	-0.7	-2.1	-2.0	-0.5	-2.0
Alcohol drinker status: Previous	0.4	0.4	1.2	0.5	1.1	-0.1	0.7	0.7	0.4	0.1	0.8
Pack years of smoking	2.2	3.2	12.4	1.1	-0.6	-0.4	1.7	1.1	1.9	3.5	1.9
Impedance of whole body	0.4	2.0	6.5	0.6	-1.7	1.6	1.5	-0.4	-1.0	-0.1	2.5
Leg fat mass (left)	0.4	1.4	3.9	-1.0	-1.2	0.7	-1.2	-0.9	-1.4	-0.8	-2.0
Arm predicted mass (left)	0.8	4.1	13.2	-2.5	0.5	-0.3	-2.6	-1.3	-1.6	-1.5	-3.6