TWAS hub - OAS1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0850	0.0280	7.5e-07	0.088	0.060	0.076	0.076	0.087	7.2e-11	7.8e-08	1.3e-09	1.4e-09	1.0e-10
2	GTEx	Esophagus Mucosa	0.0910	0.0350	1.3e-03	0.053	NA	0.044	NA	0.049	1.8e-04	NA	6.1e-04	NA	3.1e-04
3	GTEx	Testis	0.1530	0.0700	9.9e-03	-0.006	NA	0.011	NA	-0.006	1.0e+00	NA	1.0e-01	NA	7.2e-01
4	METSIM	Adipose	0.1139	0.0326	5.6e-10	0.078	0.082	0.068	0.089	0.075	9.7e-12	2.5e-12	1.9e-10	3.0e-13	2.1e-11
5	NTR	Blood	0.0152	0.0062	7.2e-04	0.005	0.008	0.003	0.007	0.003	6.6e-03	8.7e-04	3.1e-02	1.7e-03	3.0e-02
6	YFS	Blood	0.1016	0.0239	1.7e-15	0.057	0.065	0.071	0.070	0.070	3.5e-18	1.6e-20	3.0e-22	9.3e-22	5.5e-22
7	TCGA	Bladder Urothelial Carcinoma	0.0630	0.0360	3.3e-05	0.042	0.051	0.059	NA	0.034	1.8e-04	4.0e-05	1.1e-05	NA	6.7e-04
8	TCGA	Breast Invasive Carcinoma	0.0484	0.0185	3.6e-13	0.081	0.068	0.066	NA	0.077	4.1e-16	8.2e-14	2.3e-13	NA	1.7e-15
9	TCGA	Glioblastoma Multiforme	0.0970	0.0540	2.7e-03	0.087	0.089	0.075	NA	0.085	1.3e-03	1.1e-03	2.7e-03	NA	1.5e-03
10	TCGA	Head and Neck Squamous Cell Carcinoma	0.0337	0.0172	6.4e-04	0.013	0.030	0.022	NA	0.015	1.1e-02	2.3e-04	1.5e-03	NA	6.4e-03
11	TCGA	Kidney Renal Clear Cell Carcinoma	0.0805	0.0266	3.1e-15	0.140	0.154	0.159	NA	0.152	1.5e-15	6.2e-17	1.5e-17	NA	8.9e-17
12	TCGA	Kidney Renal Papillary Cell Carcinoma	0.3000	0.0990	3.8e-11	0.211	0.199	0.215	NA	0.230	2.7e-12	1.4e-11	1.7e-12	NA	2.4e-13
13	TCGA	Brain Lower Grade Glioma	0.0894	0.0307	1.2e-15	0.172	0.140	0.156	NA	0.169	3.7e-19	1.4e-15	2.1e-17	NA	8.8e-19
14	TCGA	Lung Adenocarcinoma	0.0420	0.0242	4.8e-03	0.000	0.027	0.008	NA	-0.001	2.9e-01	3.8e-04	3.6e-02	NA	3.8e-01
15	TCGA	Ovarian Serous Cystadenocarcinoma	0.0730	0.0360	2.9e-05	0.061	0.063	0.062	NA	0.042	6.0e-05	4.4e-05	5.4e-05	NA	7.3e-04
16	TCGA	Pheochromocytoma and Paraganglioma	0.1200	0.0540	6.2e-05	0.125	0.134	0.084	NA	0.118	1.1e-05	5.4e-06	3.2e-04	NA	2.0e-05
17	TCGA	Prostate Adenocarcinoma	0.1315	0.0699	6.2e-09	0.074	0.076	0.082	NA	0.082	3.9e-08	2.3e-08	6.3e-09	NA	6.2e-09
18	TCGA	Soft Tissue Sarcoma	0.0620	0.0360	6.7e-03	0.019	0.019	0.009	NA	0.004	2.6e-02	2.4e-02	9.4e-02	NA	1.9e-01
19	TCGA	Testicular Germ Cell Tumors	0.2150	0.1060	2.2e-05	0.152	0.116	0.098	NA	0.146	5.0e-06	6.9e-05	2.5e-04	NA	7.7e-06
20	TCGA	Thyroid Carcinoma	0.0870	0.0280	9.4e-14	0.133	0.145	0.138	NA	0.143	6.4e-13	5.8e-14	2.6e-13	NA	8.8e-14

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20
Ever had stillbirth, spontaneous miscarriage or termination	12.8	13.7	20.2	4.2	-3.8	3.0	4.5	3.5	4.2	3.9	3.8	2.3	3.9	3.9	4.1	3.8	3.5	3.2	3.5	4.2	4.0	4.3
Reason for reducing amount of alcohol drunk: Health precaution	4.7	5.4	9.8	2.4	-2.4	1.6	2.3	3.0	3.1	2.4	2.5	1.5	2.4	2.6	2.3	2.4	1.8	2.5	2.2	2.0	2.3	2.9
Primary Biliary Cirrhosis	3.7	5.2	11.9	2.6	-2.6	0.9	1.2	0.9	3.4	0.0	2.9	2.9	2.7	2.2	2.6	0.0	3.3	2.7	2.8	1.1	2.6	2.5
Ever had bowel cancer screening	3.5	4.1	7.0	2.0	-2.2	1.5	1.6	2.3	2.4	2.0	2.6	2.1	2.2	2.3	2.1	1.2	2.4	2.4	1.8	1.5	2.2	2.2
Blood Platelet Count	3.0	34.9	71.9	6.7	-6.5	4.2	6.3	4.0	3.8	6.9	7.8	7.1	6.7	7.3	6.6	3.2	5.8	8.5	5.1	1.6	6.5	5.8
Blood Eosinophil Count	2.9	22.3	39.9	5.4	-5.3	1.9	3.9	4.0	4.3	5.2	6.3	5.2	5.0	6.2	5.4	3.4	4.5	6.3	4.4	2.2	5.3	5.0
Medication: Atenolol	2.8	3.5	6.4	1.9	-2.1	0.7	1.5	1.8	1.7	1.9	2.5	2.1	2.1	2.4	2.1	0.8	2.1	2.3	1.9	1.1	2.2	2.0
High blood pressure (mother)	2.8	3.9	6.7	2.6	-2.4	2.0	2.2	0.4	1.0	2.5	1.8	1.5	2.4	2.0	2.6	1.8	1.9	2.1	2.0	1.5	2.5	2.1
Hearing aid user	2.7	3.1	6.5	-1.7	1.7	-0.5	-2.6	-1.3	-1.9	-1.8	-2.0	-0.9	-1.9	-1.8	-1.8	-1.3	-2.2	-1.5	-1.7	-2.5	-1.9	-2.2
Blood White Count	2.5	18.4	33.4	4.9	-4.8	2.7	2.4	3.0	3.7	5.1	5.7	5.0	4.9	5.3	4.9	2.1	4.6	5.8	4.2	1.6	4.9	4.5
Tinnitus: Yes, but not now, but have in the past	2.3	2.5	5.0	2.0	-1.6	0.7	1.0	1.3	1.4	1.9	2.0	2.2	1.7	1.8	1.8	0.2	1.8	2.1	1.8	0.1	1.7	1.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	2.3	2.7	3.9	-1.6	1.9	-1.5	-1.9	-1.9	-1.5	-1.6	-1.9	-1.8	-1.8	-1.9	-1.5	-1.5	-1.4	-2.0	-1.6	-0.8	-1.6	-1.9
BMI	2.2	12.5	18.1	-4.3	4.2	-1.9	-3.4	-2.1	-3.5	-4.0	-3.5	-2.6	-4.1	-3.8	-4.2	-3.6	-3.4	-3.5	-4.0	-3.4	-4.2	-4.2
Mouth/teeth dental problems: Dentures	2.2	3.8	5.4	-2.0	2.3	-1.5	-1.9	-2.1	-2.2	-2.1	-1.8	-1.2	-2.1	-2.2	-2.1	-2.2	-1.8	-1.7	-1.6	-2.0	-2.2	-2.3
HbA1C	2.1	2.4	4.2	-1.8	2.0	-1.0	-0.7	-0.9	-1.4	-1.7	-1.9	-1.6	-1.6	-1.8	-2.0	-0.9	-1.7	-1.6	-1.9	-1.2	-1.8	-1.6
Body mass index (BMI)	2.1	8.7	12.7	-3.6	3.6	-2.0	-2.5	-1.9	-3.3	-3.5	-3.1	-2.7	-3.5	-3.1	-3.4	-2.5	-3.0	-3.1	-2.7	-2.3	-3.5	-3.4
Arm fat percentage (left)	2.1	8.3	12.8	-3.6	3.4	-2.4	-2.5	-1.8	-3.0	-3.6	-2.9	-2.6	-3.5	-3.0	-3.4	-2.3	-3.1	-2.8	-2.5	-2.4	-3.4	-3.2
Arm fat mass (left)	2.0	8.4	13.0	-3.6	3.6	-2.3	-2.4	-1.6	-3.0	-3.6	-2.9	-2.7	-3.5	-3.0	-3.4	-2.3	-3.1	-2.9	-2.7	-2.3	-3.5	-3.2
Hearing difficulty/problems: Yes	1.9	3.0	5.1	-1.8	2.1	-1.6	-1.6	-1.7	-0.8	-1.8	-1.8	-1.4	-1.9	-2.1	-1.9	-1.3	-1.9	-1.5	-2.3	-1.6	-1.9	-2.0
Arm fat mass (right)	1.9	8.0	12.6	-3.5	3.5	-2.2	-2.1	-1.5	-2.9	-3.5	-2.9	-2.8	-3.5	-2.9	-3.4	-2.0	-3.1	-2.9	-2.6	-2.0	-3.4	-3.1
Severe depression (siblings)	1.8	2.0	6.2	1.2	-1.8	1.3	1.7	1.0	1.0	1.5	1.1	0.2	1.6	1.2	1.2	2.1	1.5	0.8	1.1	2.5	1.3	1.8
Mouth/teeth dental problems: Mouth ulcers	1.8	2.9	8.3	1.9	-1.9	1.4	1.8	1.7	2.9	1.8	2.0	1.7	1.7	1.5	1.7	0.9	1.9	1.8	1.0	1.2	1.7	1.6
Medication: Omeprazole (e.g. Zanprol)	1.8	2.2	3.9	1.6	-1.5	1.5	1.7	2.0	1.8	1.5	1.7	1.2	1.3	1.8	1.4	1.3	1.1	1.5	1.3	0.9	1.3	1.6
Schizophrenia vs Biploar Disorder	1.7	2.3	4.1	-1.8	1.7	-1.6	-1.1	-0.7	0.0	-2.0	-1.6	-1.3	-1.9	-1.5	-1.9	-0.7	-1.6	-1.8	-1.9	-0.8	-2.0	-1.7
Waist Hip Ratio (WHR)	1.7	7.6	15.5	3.3	-3.2	2.4	2.1	1.8	2.1	3.1	3.4	3.4	3.1	3.1	3.2	1.2	2.8	3.9	3.0	0.5	3.1	2.8
Medication: Levothyroxine sodium	1.7	2.9	5.9	1.5	-2.0	1.5	1.1	1.9	1.1	1.8	2.4	1.9	2.0	2.1	1.4	1.3	1.5	2.4	1.6	0.6	1.6	2.0
Arm fat percentage (right)	1.7	6.8	10.8	-3.3	3.1	-2.1	-1.9	-1.5	-2.6	-3.3	-2.7	-2.7	-3.2	-2.7	-3.1	-1.7	-2.9	-2.6	-2.4	-1.8	-3.1	-2.8
Hip circumference	1.7	7.3	11.4	-3.3	3.4	-1.7	-2.2	-1.4	-3.3	-3.2	-2.8	-2.5	-3.3	-2.7	-3.1	-2.0	-2.9	-2.8	-2.5	-2.1	-3.2	-3.1
Hair/balding pattern: Pattern 4	1.7	4.0	6.6	2.0	-1.8	2.3	1.3	2.2	1.9	1.9	2.6	2.4	2.0	2.4	2.1	0.9	2.3	2.4	2.5	0.9	2.1	2.1
Whole body fat mass	1.7	7.2	11.8	-3.4	3.3	-2.1	-2.0	-1.5	-2.7	-3.4	-2.8	-2.6	-3.3	-2.9	-3.2	-2.1	-2.8	-2.8	-2.2	-1.9	-3.2	-2.9
Mineral and other dietary supplements	1.7	2.3	5.4	-1.6	1.5	-1.4	-1.2	-2.3	-1.1	-1.4	-2.0	-1.9	-1.4	-2.1	-1.6	-0.8	-1.5	-2.0	-1.6	-0.3	-1.5	-1.5
Alzheimer’s Disease (including proxy)	1.6	2.4	9.2	-1.3	1.5	-1.6	-0.2	-1.6	-0.3	-1.4	-2.1	-3.0	-1.6	-1.9	-1.1	0.2	-1.7	-2.7	-0.9	1.5	-1.2	-0.9
Number of full sisters	1.6	2.0	7.8	-1.3	1.1	-0.5	-1.9	-2.8	-0.8	-1.3	-1.4	-0.6	-1.1	-1.8	-1.2	-2.2	-0.8	-1.1	-1.1	-1.7	-1.2	-1.6
Supplements: Fish oil (including cod liver oil)	1.6	2.1	4.1	1.7	-1.5	1.1	0.8	1.7	1.3	1.4	1.9	1.9	1.4	1.8	1.6	0.4	1.7	2.0	1.7	0.2	1.5	1.4
Supplements: Calcium	1.6	1.8	4.6	1.4	-1.1	1.3	1.2	2.1	1.2	1.3	1.6	1.3	1.2	1.7	1.4	0.9	1.1	1.2	1.8	1.0	1.2	1.5
Leg fat mass (left)	1.6	6.2	9.9	-3.1	3.1	-1.8	-2.2	-1.1	-2.9	-3.1	-2.3	-1.9	-3.0	-2.4	-3.0	-2.5	-2.4	-2.3	-2.1	-2.3	-3.0	-2.8
Trunk fat mass	1.5	6.4	10.9	-3.3	3.1	-2.2	-1.5	-1.3	-2.5	-3.3	-2.7	-2.7	-3.1	-2.7	-3.1	-1.7	-2.8	-2.7	-2.0	-1.5	-3.1	-2.5
Number of incorrect matches in round	1.5	2.5	4.3	1.6	-1.6	0.5	1.6	2.0	1.6	1.4	2.1	1.9	1.6	1.9	1.7	0.3	1.9	1.9	1.6	0.8	1.7	1.6
Illnesses of mother	1.5	1.9	4.0	-2.0	1.8	-1.1	-1.5	0.2	-0.8	-1.9	-0.8	-0.6	-1.8	-1.0	-1.9	-1.6	-1.3	-1.1	-0.9	-1.6	-1.8	-1.4
Hypothyroidism/myxoedema (self-reported)	1.5	2.9	6.5	1.5	-1.9	1.2	1.3	2.2	0.8	1.5	2.4	1.8	1.9	2.4	1.5	1.4	1.3	2.5	1.7	0.6	1.7	2.1
Body fat percentage	1.5	6.1	10.5	-3.2	3.0	-2.1	-1.8	-1.3	-2.5	-3.2	-2.5	-2.4	-3.0	-2.6	-3.1	-1.9	-2.7	-2.4	-1.9	-1.9	-3.0	-2.6
Angina (self-reported)	1.5	1.9	3.3	1.4	-1.7	1.8	1.4	0.7	1.2	1.4	1.4	0.7	1.6	1.4	1.3	1.3	1.2	1.4	1.7	1.4	1.5	1.8
Leg fat mass (right)	1.5	6.0	9.6	-3.0	3.1	-1.9	-2.2	-1.0	-2.6	-3.1	-2.2	-1.8	-3.0	-2.4	-2.9	-2.7	-2.3	-2.3	-2.1	-2.4	-2.9	-2.8
Handedness (chirality/laterality): Left-handed	1.5	1.8	3.5	1.6	-1.6	0.9	1.2	1.0	1.3	1.9	1.4	1.0	1.7	1.4	1.5	0.8	1.6	1.3	1.4	1.2	1.5	1.5
Average weekly champagne plus white wine intake	1.5	2.1	4.5	1.6	-1.6	0.7	1.5	1.3	2.1	1.5	1.7	1.4	1.5	1.7	1.6	1.4	1.3	1.6	0.8	1.0	1.6	1.4
Risk taking	1.5	2.2	3.8	1.7	-1.6	1.6	1.4	1.2	0.8	1.6	1.6	1.6	1.5	1.9	1.8	1.2	1.3	1.7	1.8	0.5	1.7	1.4
Basal cell carcinoma (self-reported)	1.5	1.8	4.2	-1.5	1.5	-1.1	-1.4	-0.9	-2.0	-1.5	-1.0	-0.4	-1.4	-1.2	-1.5	-1.8	-1.3	-0.7	-0.9	-2.0	-1.5	-1.6
Intelligence (Savage-Jansen 2018)	1.4	4.3	6.4	2.3	-2.2	1.8	2.5	2.1	1.8	2.2	2.3	1.9	2.2	2.5	2.2	1.8	1.9	2.1	1.9	1.6	2.3	2.3
Chronotype (morning person)	1.4	3.3	6.1	2.2	-2.2	1.2	0.1	0.4	2.1	2.0	2.1	2.4	1.9	1.9	2.3	0.0	2.5	1.9	2.4	0.5	2.2	1.6
Trunk fat percentage	1.4	5.8	10.1	-3.2	2.9	-2.2	-1.6	-1.5	-2.2	-3.1	-2.6	-2.6	-2.9	-2.6	-3.0	-1.6	-2.7	-2.5	-1.7	-1.6	-2.9	-2.4
Diverticular disease/diverticulitis (self-reported)	1.4	1.7	3.0	1.6	-1.5	1.1	1.1	0.9	0.3	1.7	1.5	1.5	1.5	1.4	1.6	0.1	1.6	1.7	1.2	0.5	1.5	1.1
Medication: Amlodipine	1.4	1.9	3.6	-1.4	1.5	-0.7	-1.2	-1.1	-1.9	-1.4	-1.7	-1.5	-1.4	-1.5	-1.5	-0.3	-1.6	-1.7	-1.8	-0.6	-1.5	-1.5
Medication: Omeprazole	1.4	1.6	3.0	1.4	-1.2	1.5	1.3	1.6	1.7	1.2	1.5	1.5	1.1	1.6	1.2	0.6	1.2	1.4	1.3	0.3	1.1	1.3
Lupus	1.3	1.9	4.9	-1.5	1.2	-0.7	-2.2	-1.6	-1.5	-1.3	-1.5	-0.9	-1.2	-1.7	-1.5	-1.3	-1.1	-1.3	-1.5	-1.1	-1.4	-1.7
Angina	1.3	1.7	3.3	1.3	-1.6	1.8	1.0	0.5	1.2	1.3	1.4	1.0	1.6	1.3	1.3	0.9	1.3	1.5	1.6	1.0	1.4	1.6
Financial difficulties in last 2 years	1.3	1.8	3.2	-1.4	1.6	-1.2	-0.6	-1.2	-1.6	-1.6	-1.6	-1.8	-1.4	-1.5	-1.5	-0.2	-1.4	-1.6	-1.4	-0.1	-1.5	-1.3
Heart attack	1.3	1.6	3.8	1.2	-1.6	1.3	0.8	1.2	0.4	1.4	1.4	1.1	1.4	1.4	1.2	1.0	1.2	1.3	1.9	1.1	1.3	1.6
Blood clot in the leg (DVT)	1.3	1.7	3.0	1.6	-1.1	1.1	1.3	1.4	1.3	1.3	1.7	1.3	1.3	1.7	1.5	0.7	1.2	1.6	1.4	0.7	1.5	1.5
Family relationship satisfaction	1.3	1.6	4.0	1.3	-1.6	1.7	2.0	-0.1	0.4	1.6	1.0	0.8	1.7	0.8	1.3	0.9	1.3	1.0	1.3	1.4	1.4	1.5
Unable to work because of sickness or disability	1.3	1.7	7.8	-1.1	1.2	-0.6	-1.5	-1.3	-2.8	-1.0	-1.1	-0.5	-1.2	-1.2	-1.1	-1.5	-1.4	-0.6	-0.7	-2.0	-1.2	-1.5
Respiratory disease	1.2	2.7	10.6	-1.8	1.5	-1.0	-0.3	-1.1	-3.3	-1.8	-2.1	-2.5	-1.7	-1.4	-1.5	0.4	-2.5	-1.8	-1.4	-0.4	-1.5	-1.3
Ever unenthusiastic/disinterested for a whole week	1.2	1.4	3.2	-1.4	1.2	0.0	-1.4	-0.7	-1.6	-1.4	-1.1	-0.3	-1.2	-1.2	-1.3	-1.7	-1.1	-0.8	-0.9	-1.8	-1.3	-1.4
Leg fat percentage (right)	1.2	4.3	6.9	-2.6	2.5	-1.6	-1.8	-0.9	-2.3	-2.6	-1.8	-1.4	-2.5	-1.9	-2.4	-2.4	-1.9	-1.7	-1.8	-2.3	-2.4	-2.4
Age at first live birth	1.2	2.0	3.1	1.6	-1.6	1.8	1.1	0.9	1.6	1.7	1.0	1.0	1.6	1.4	1.7	1.6	1.4	1.1	1.5	1.5	1.7	1.6
Had major operations	1.2	1.4	4.2	-1.1	1.0	-0.3	-2.0	-0.7	-1.8	-0.9	-0.4	0.5	-0.9	-0.9	-1.1	-1.9	-0.5	-0.1	-1.3	-2.0	-1.0	-1.6
Breast cancer (self-reported)	1.2	1.5	4.7	1.3	-1.3	1.3	1.5	0.6	2.2	1.2	1.0	0.7	1.3	0.9	1.3	0.9	1.3	0.8	1.2	1.4	1.3	1.4
Ever taken oral contraceptive pill	1.2	1.3	3.0	1.2	-1.3	0.6	1.3	1.1	0.6	1.2	0.9	0.4	1.1	1.1	1.2	1.7	0.8	0.8	1.6	1.5	1.2	1.5
Leg fat percentage (left)	1.2	4.2	7.1	-2.7	2.4	-1.4	-1.9	-0.9	-2.6	-2.6	-1.9	-1.6	-2.4	-2.0	-2.4	-2.1	-2.0	-1.7	-1.7	-2.1	-2.4	-2.3
Ever depressed for a whole week	1.2	1.4	2.6	-1.6	1.2	-0.4	-1.1	-0.6	-1.2	-1.6	-1.2	-1.1	-1.4	-1.4	-1.6	-0.9	-1.3	-1.2	-1.1	-0.7	-1.5	-1.2
Myopia	1.2	1.7	6.5	1.5	-1.3	0.5	0.6	0.3	2.6	1.6	1.5	1.1	1.4	1.0	1.5	0.2	1.8	1.1	1.3	1.2	1.4	1.4
Deep venous thrombosis (DVT) (self-reported)	1.2	1.5	2.7	1.4	-1.0	1.2	1.1	1.4	1.1	1.1	1.6	1.2	1.3	1.6	1.4	0.7	1.1	1.4	1.3	0.6	1.4	1.4
Alzheimer’s Disease (in mother)	1.1	1.3	3.8	1.3	-1.3	0.8	1.5	0.9	1.0	1.2	0.9	-0.0	1.2	1.0	1.2	1.5	0.7	0.6	1.2	1.9	1.2	1.6
Major Depression (MDD)	1.1	1.4	2.9	-1.5	1.1	-0.9	-1.6	-0.2	0.0	-1.3	-1.1	-0.5	-1.2	-1.1	-1.5	-1.2	-1.3	-0.8	-1.1	-1.7	-1.4	-1.3
Triglycerides	1.1	1.8	4.1	-1.4	1.4	-0.8	-1.7	-1.1	-2.0	-1.5	-1.4	-1.4	-1.5	-1.3	-1.4	-0.3	-1.7	-1.3	-1.5	-0.7	-1.5	-1.4
Type 2 Diabetes (T2D) (2012)	1.1	1.2	5.7	1.3	-1.1	0.8	1.4	0.9	0.9	0.0	0.7	-0.2	1.2	0.8	0.8	2.1	0.9	0.3	0.6	2.4	1.0	1.4
Frequency of tenseness / restlessness in last 2 weeks	1.1	1.7	4.4	-1.5	1.2	-0.9	-0.6	-1.0	-2.1	-1.4	-1.2	-0.7	-1.4	-1.3	-1.4	-1.7	-1.1	-1.2	-1.1	-1.4	-1.4	-1.6
Weight	1.1	5.6	8.9	-2.9	3.0	-1.6	-1.2	-1.5	-2.7	-2.9	-2.5	-2.5	-2.9	-2.6	-2.8	-1.8	-2.5	-2.6	-2.0	-1.4	-2.9	-2.5
Birth weight of first child	1.1	2.1	4.1	-1.5	1.6	-2.0	-1.0	-1.0	-0.9	-1.6	-1.7	-1.8	-1.6	-1.7	-1.5	-1.0	-1.2	-1.8	-1.6	-0.3	-1.6	-1.5
Chest pain or discomfort	1.1	1.6	6.5	-1.4	1.2	-0.1	-1.0	-1.8	-2.5	-1.1	-1.1	-0.9	-1.1	-1.3	-1.3	-1.4	-1.1	-0.6	-0.9	-1.4	-1.2	-1.3
Forced expiratory volume in 1-second (FEV1), predicted	1.1	2.3	3.9	1.8	-1.6	1.6	2.0	0.1	1.4	1.8	1.4	0.8	1.8	1.2	1.7	1.1	1.6	1.4	1.7	1.7	1.7	1.8
Medication: Blood pressure	1.1	2.2	3.4	1.6	-1.6	0.9	1.3	1.0	1.8	1.6	1.8	1.5	1.6	1.7	1.7	0.5	1.7	1.7	1.6	0.9	1.7	1.5
Heart attack/myocardial infarction (self-reported)	1.1	1.5	3.1	1.1	-1.4	1.4	0.7	1.4	0.2	1.3	1.4	1.0	1.3	1.4	1.0	1.1	1.0	1.4	1.8	0.9	1.2	1.6
Qualifications: CSEs or equivalent	1.0	1.4	2.3	-1.2	1.2	-0.9	-1.1	-1.5	-1.5	-1.1	-1.3	-1.3	-1.1	-1.5	-1.3	-0.6	-1.3	-1.1	-1.2	-0.6	-1.3	-1.1
Supplements: Glucosamine	1.0	1.3	3.3	1.2	-1.0	1.8	0.5	1.2	0.9	1.1	1.4	1.6	1.0	1.5	1.3	0.3	1.4	1.2	1.1	0.3	1.2	1.0
Worrier / anxious feelings	1.0	1.9	3.7	1.6	-1.5	1.3	1.2	0.2	1.6	1.8	1.5	1.7	1.7	1.3	1.6	0.1	1.9	1.6	1.2	0.7	1.7	1.3
Number of live births	1.0	1.4	3.2	1.5	-1.4	0.8	0.7	1.3	0.4	1.0	1.6	1.8	1.2	1.6	1.4	0.1	1.3	1.5	1.2	-0.0	1.3	0.9
Illnesses of father: Heart disease	1.0	1.4	3.4	1.2	-1.2	1.2	0.4	1.7	1.3	1.2	1.5	1.8	1.2	1.5	1.1	0.3	1.3	1.7	0.9	-0.2	1.1	1.0
Long-standing illness, disability or infirmity	1.0	1.5	5.7	-1.2	1.1	-0.7	-1.7	-0.7	-1.7	-1.3	-0.3	0.4	-1.0	-0.9	-1.3	-2.1	-0.9	0.1	-0.8	-2.4	-1.2	-1.2
Medication: Bendroflumethiazide	1.0	1.5	5.7	-1.1	1.1	-1.1	-2.2	-0.8	-0.2	-1.1	-0.6	0.3	-1.2	-0.9	-1.0	-2.4	-0.5	-0.4	-0.9	-2.3	-1.1	-1.5
Alzheimer’s Disease (in father)	0.9	1.0	4.2	-0.2	0.6	-0.9	1.1	-1.2	0.8	-0.3	-1.3	-2.1	-0.6	-1.3	-0.3	0.6	-0.6	-1.8	0.0	1.9	-0.4	-0.1
Hypothyroidism (self reported)	0.9	2.0	6.5	1.1	-1.4	0.9	0.4	2.2	0.9	1.1	2.3	1.9	1.4	2.2	1.1	0.9	0.8	2.5	0.5	-0.4	1.2	1.4
Lung FVC	0.9	4.8	12.4	2.7	-2.4	1.9	0.7	1.8	1.5	2.5	2.8	3.5	2.4	2.6	2.4	0.2	2.5	3.0	2.2	-0.3	2.4	1.8
Average weekly spirits intake	0.9	1.1	5.5	-0.7	1.0	0.9	-1.4	-2.4	-0.5	-0.7	-1.2	-0.8	-0.9	-1.5	-0.9	-0.9	-0.5	-1.0	-0.8	-0.7	-1.0	-1.2
Serious illness, injury or assault to yourself	0.9	1.0	4.2	0.8	-0.5	0.1	0.5	2.0	0.0	0.5	1.6	1.7	0.5	1.7	0.8	-0.1	0.8	1.6	1.2	-0.6	0.7	0.6
Heel bone mineral density (BMD) T-score, automated (right)	0.9	2.1	4.7	1.7	-1.3	1.6	1.0	2.2	1.2	1.6	1.7	1.4	1.4	2.0	1.6	1.2	1.3	1.6	0.9	0.8	1.5	1.4
Hypertension (Self-reported)	0.9	2.5	6.3	1.6	-1.6	1.5	0.2	1.7	1.6	1.7	2.2	2.1	1.7	2.0	1.6	0.6	1.3	2.5	1.8	-0.2	1.6	1.6
Osteoporosis (self-reported)	0.9	1.2	3.2	0.7	-1.2	1.8	1.4	1.1	0.4	1.0	0.9	0.5	1.3	1.0	0.7	1.6	0.8	0.9	0.8	1.4	1.0	1.4
Medication: Atorvastatin	0.9	1.1	1.8	-1.1	1.2	-1.1	-1.0	-1.1	-0.3	-1.2	-1.2	-0.8	-1.3	-1.3	-1.2	-1.2	-0.7	-1.3	-1.0	-0.8	-1.3	-1.2
Age at First Birth	0.8	1.1	2.5	1.3	-1.4	1.6	0.5	0.5	0.9	1.2	1.0	0.8	1.2	1.3	1.2	1.1	0.7	1.2	0.6	0.6	1.2	1.2
Medication for hormone replacement therapy	0.8	0.9	3.1	1.0	-0.8	1.3	-0.3	0.5	0.9	0.9	1.1	1.8	0.8	0.8	1.0	-0.7	1.1	1.2	1.0	-0.7	0.9	0.4
Medication: Co-codamol	0.8	1.0	2.6	-1.0	0.8	-1.3	0.8	-1.6	-0.3	-0.9	-1.1	-1.4	-0.7	-1.4	-1.0	-0.0	-0.7	-1.2	-1.1	0.6	-0.9	-0.7
Leg predicted mass (left)	0.8	4.0	7.0	-2.4	2.6	-1.5	-1.0	-1.1	-1.8	-2.4	-2.2	-2.0	-2.6	-2.2	-2.4	-1.5	-2.1	-2.5	-1.9	-1.1	-2.5	-2.2
Waist circumference	0.8	3.0	6.8	-2.1	2.1	-1.1	-1.1	-0.9	-2.6	-2.2	-1.6	-1.4	-2.1	-1.7	-2.0	-1.5	-1.8	-1.3	-1.4	-1.6	-2.0	-1.9
Father’s age at death	0.8	1.1	3.7	0.8	-1.0	0.8	0.4	1.0	1.6	1.0	1.4	1.9	1.0	0.8	0.7	-0.9	1.7	1.3	0.6	-0.4	0.8	0.7
Comparative body size at age 10	0.8	2.2	6.6	-1.3	1.2	-0.6	-2.4	-2.6	-1.6	-1.3	-1.5	-0.8	-1.3	-1.8	-1.3	-2.0	-0.9	-1.2	-1.2	-1.6	-1.3	-1.7
Mood swings	0.8	1.4	3.6	1.1	-1.3	1.5	0.7	1.2	1.0	1.3	1.5	1.9	1.2	1.1	1.0	-0.6	1.6	1.3	1.4	-0.1	1.0	0.9
Loneliness, isolation	0.8	1.1	3.0	-1.2	1.0	-0.2	-1.4	-0.3	-1.5	-0.9	-0.8	-0.4	-1.1	-0.8	-1.2	-1.5	-1.0	-0.5	-1.2	-1.7	-1.2	-1.4
Medication for cholesterol	0.8	1.2	2.0	-1.3	1.2	-1.3	-0.7	-0.9	-0.4	-1.2	-1.2	-0.9	-1.3	-1.4	-1.3	-0.8	-0.9	-1.3	-1.3	-0.6	-1.3	-1.2
Back pain experienced in last month	0.8	1.2	2.2	-1.3	1.2	-1.5	0.4	-1.2	-0.9	-1.2	-1.1	-1.0	-1.2	-1.4	-1.4	-1.0	-0.9	-1.1	-0.9	-0.7	-1.4	-1.2
Fasting Glucose	0.7	0.8	3.2	0.9	-1.3	-0.2	0.7	-0.1	1.8	0.9	1.0	1.0	0.8	0.6	0.9	-0.1	1.5	0.9	1.0	0.6	0.9	0.9
Ever had hysterectomy (womb removed)	0.7	0.7	2.0	0.8	-0.9	0.9	0.2	0.9	1.0	0.6	1.1	1.4	0.9	0.8	0.8	-0.2	1.1	1.3	0.7	-0.4	0.9	0.6
Leg fat-free mass (left)	0.7	3.9	6.8	-2.4	2.6	-1.4	-1.0	-1.1	-1.9	-2.4	-2.1	-2.0	-2.5	-2.1	-2.3	-1.5	-2.0	-2.4	-1.8	-1.1	-2.4	-2.1
Heel bone mineral density (BMD) T-score, automated (left)	0.7	1.5	3.2	1.4	-1.3	1.8	1.3	1.5	0.7	1.4	1.2	0.6	1.2	1.6	1.4	1.7	0.9	1.1	0.5	1.3	1.3	1.3
Impedance of leg (left)	0.7	3.4	6.5	2.0	-2.3	1.0	1.3	1.5	1.6	2.0	2.3	2.0	2.2	2.2	2.0	1.0	1.9	2.5	2.0	0.7	2.1	2.1
Diabetes (self-reported)	0.7	1.1	2.9	0.9	-1.2	1.5	1.1	1.4	-0.0	1.0	1.5	1.2	1.1	1.3	0.8	0.7	0.8	1.7	0.9	0.0	1.0	1.1
Impedance of arm (right)	0.7	3.2	6.6	1.9	-2.1	0.3	2.6	0.9	2.5	1.8	1.7	0.9	2.0	1.6	1.8	2.2	1.4	1.8	1.7	2.0	1.9	2.3
Arm fat-free mass (right)	0.7	3.8	6.3	-2.3	2.5	-1.3	-1.4	-0.9	-2.4	-2.3	-2.0	-1.8	-2.4	-2.0	-2.3	-1.8	-1.9	-2.3	-1.7	-1.2	-2.3	-2.1
Health satisfaction	0.7	0.9	1.5	-1.1	0.9	-0.1	-0.6	-1.1	-1.0	-1.1	-0.9	-0.5	-1.0	-1.2	-1.1	-1.1	-1.0	-0.6	-0.8	-1.2	-1.1	-1.0
Heart disease (mother)	0.7	0.9	1.8	1.1	-1.2	0.0	0.3	0.8	1.3	1.0	1.1	1.1	1.2	0.8	1.1	0.2	1.2	1.1	0.8	0.6	1.1	1.1
Pulse rate, automated reading	0.7	2.2	4.8	-1.7	1.7	-0.3	-1.4	-1.1	-1.6	-1.6	-1.3	-0.8	-1.7	-1.4	-1.8	-1.3	-1.8	-1.0	-1.4	-2.2	-1.8	-1.7
Leg predicted mass (right)	0.7	3.5	5.8	-2.3	2.4	-1.1	-0.8	-1.2	-1.9	-2.2	-2.2	-2.2	-2.3	-2.1	-2.2	-1.0	-2.0	-2.4	-1.6	-0.7	-2.2	-1.9
Guilty feelings	0.7	1.0	2.9	0.9	-1.1	0.4	1.7	1.0	0.9	1.1	1.2	1.0	1.2	0.9	1.0	-0.0	1.1	1.3	1.1	0.3	1.1	1.1
Impedance of whole body	0.7	3.6	5.5	2.0	-2.3	0.7	1.9	1.2	2.3	2.0	2.1	1.7	2.3	2.0	2.0	1.6	1.8	2.4	2.2	1.2	2.1	2.4
Irritable Bowel Disease (IBD)	0.6	1.4	7.8	1.5	-1.0	0.9	0.8	0.6	2.8	1.2	1.1	1.2	1.0	1.0	1.3	0.6	1.2	1.0	1.2	0.3	1.2	1.1
Mean Putamen Volume	0.6	0.7	1.8	-1.0	0.9	-0.3	-0.5	0.0	-1.4	-1.1	-0.8	-1.0	-0.9	-0.6	-1.1	-0.0	-1.2	-0.9	-0.7	-0.3	-1.0	-0.6
Heel T-Score	0.6	4.7	7.2	2.4	-2.3	1.7	1.9	2.0	1.6	2.5	2.5	2.2	2.4	2.7	2.5	1.3	2.5	2.4	2.5	1.4	2.5	2.5
Eye problems/disorders: Diabetes related eye disease	0.6	0.6	1.5	-1.0	0.7	-0.5	-0.5	-0.6	-1.2	-0.9	-0.7	-0.4	-0.8	-0.8	-0.9	-1.0	-0.8	-0.6	-0.8	-1.1	-0.9	-0.9
Impedance of leg (right)	0.6	3.0	5.7	2.0	-2.0	0.6	1.2	1.6	1.8	1.8	2.3	2.3	1.9	2.1	1.9	0.5	2.0	2.4	1.7	0.3	1.9	1.8
Relative age voice broke	0.6	0.9	1.6	-1.2	0.9	-0.6	-1.0	-1.3	-0.5	-1.2	-1.0	-0.5	-1.1	-1.0	-1.0	-0.7	-0.9	-0.9	-0.7	-1.0	-1.0	-1.0
Bilateral oophorectomy (both ovaries removed)	0.6	0.7	1.3	-1.1	1.1	-0.9	-1.1	-0.7	0.3	-1.1	-1.0	-0.9	-1.0	-1.1	-0.9	-0.6	-0.8	-0.9	-0.3	-0.5	-1.0	-0.8
Chronic bronchitis/emphysema (father)	0.6	0.7	1.8	-1.0	0.9	-1.4	0.1	0.0	-0.3	-1.1	-0.9	-1.2	-0.9	-0.9	-1.0	0.0	-0.7	-1.3	-0.7	0.5	-0.9	-0.4
Had menopause	0.6	0.8	1.6	-1.1	1.1	-1.3	-0.9	0.2	-0.9	-1.3	-0.6	-0.8	-1.2	-0.6	-1.0	-0.8	-0.7	-1.1	-0.5	-0.3	-1.1	-0.9
Pain all over the body in last month	0.6	0.6	3.4	-0.5	0.6	0.4	-1.5	0.5	-1.0	-0.5	0.1	0.5	-0.7	0.1	-0.4	-1.2	-0.6	0.3	-0.5	-1.8	-0.5	-0.8
Medication: Simvastatin	0.6	0.8	4.4	0.2	-0.5	1.4	0.9	1.3	-1.3	0.4	0.3	-0.6	0.6	0.8	0.2	2.1	-0.9	0.8	0.9	0.6	0.4	1.2
Fluid intelligence score	0.6	1.3	2.4	1.3	-1.1	1.3	1.1	1.5	1.5	1.2	1.3	1.2	1.1	1.3	1.1	0.7	1.0	1.1	0.9	0.5	1.1	1.1
Illnesses of siblings	0.6	0.8	2.6	-0.8	1.2	-0.8	-0.4	-0.3	-0.4	-0.9	-1.2	-1.1	-1.0	-1.2	-1.0	-0.4	-0.7	-1.6	-0.9	0.1	-1.1	-1.0
Falls in the last year	0.6	0.8	2.9	-0.7	0.6	-0.7	-0.6	-1.6	-1.7	-0.7	-1.1	-1.1	-0.7	-1.0	-0.6	-0.6	-1.0	-0.7	-0.6	-0.5	-0.6	-0.9
Pulse rate	0.6	1.0	7.0	-0.7	0.8	0.8	-1.2	0.8	-1.5	-0.8	0.0	0.5	-0.8	0.2	-0.8	-0.7	-1.2	0.7	-1.2	-2.6	-0.8	-1.1
Qualifications: A levels/AS levels or equivalent	0.6	1.2	6.0	0.6	-1.2	1.2	2.4	1.2	1.3	0.9	0.9	0.5	1.1	0.9	0.7	1.2	1.0	0.5	0.6	1.6	0.8	1.2
Depression (self-reported)	0.6	0.7	2.5	-0.9	0.9	-1.6	-0.7	-0.2	-1.2	-0.9	-0.6	-0.3	-0.9	-0.7	-0.9	-1.1	-0.6	-0.8	-0.7	-0.8	-0.9	-1.1
Glaucoma (self-reported)	0.6	0.7	1.5	-0.9	0.6	-1.2	-0.1	-0.9	-0.6	-1.0	-0.9	-1.1	-0.8	-1.1	-1.0	-0.4	-0.7	-0.9	-1.1	-0.1	-1.0	-0.8
Birth weight	0.6	1.3	5.5	-0.8	1.0	-1.7	1.0	-0.3	0.1	-1.1	-1.4	-2.3	-1.0	-0.8	-0.8	1.0	-1.1	-1.9	-1.1	1.5	-0.8	-0.4
Pulse wave peak to peak time	0.6	0.8	2.5	0.7	-1.0	1.3	1.6	0.2	1.1	1.0	0.7	0.4	1.1	0.3	0.7	0.8	0.9	0.8	0.5	1.0	0.8	0.9
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.6	0.7	3.5	-0.9	0.9	0.0	-0.7	-0.1	-1.9	-0.9	-0.8	-0.4	-0.8	-0.5	-0.9	-0.7	-1.0	-0.6	-0.5	-1.0	-0.9	-0.8
Arm predicted mass (right)	0.6	3.2	5.5	-2.1	2.4	-1.1	-1.3	-0.9	-2.2	-2.2	-1.9	-1.8	-2.3	-1.8	-2.1	-1.6	-1.8	-2.1	-1.6	-1.0	-2.1	-2.0
Suffer from ‘nerves’	0.6	0.9	4.8	-0.5	0.5	0.6	-1.3	-0.5	-1.5	-0.3	-0.2	0.6	-0.4	-0.5	-0.6	-1.8	-0.5	0.4	-1.0	-2.2	-0.6	-1.2
Leg pain on walking	0.6	0.7	1.9	0.8	-0.6	1.2	0.1	0.2	1.0	0.9	1.0	1.4	0.7	0.7	1.0	-0.8	1.0	1.2	0.7	-0.7	0.9	0.3
Knee pain experienced in last month	0.6	0.9	3.8	0.7	-0.7	1.1	1.7	0.1	0.7	0.9	0.4	-0.6	0.8	0.4	0.7	1.7	0.4	0.2	1.0	1.9	0.7	1.2
Leg fat-free mass (right)	0.6	3.2	5.4	-2.2	2.3	-1.1	-0.8	-1.0	-1.9	-2.2	-2.0	-2.0	-2.2	-2.0	-2.1	-1.1	-1.9	-2.2	-1.6	-0.7	-2.2	-1.8
Basal metabolic rate	0.6	3.5	5.9	-2.2	2.4	-1.1	-0.8	-1.0	-2.2	-2.3	-2.0	-2.1	-2.3	-2.0	-2.2	-1.2	-1.9	-2.3	-1.8	-0.7	-2.2	-2.0
Arm fat-free mass (left)	0.6	2.8	5.1	-2.0	2.2	-0.8	-0.8	-0.6	-2.1	-2.0	-1.8	-1.8	-2.1	-1.7	-1.9	-1.3	-1.8	-1.9	-1.7	-0.9	-2.0	-1.9
Vascular/heart problems diagnosed by doctor	0.6	1.7	4.5	-1.2	1.2	-1.3	0.1	-1.1	-1.1	-1.4	-1.8	-1.8	-1.4	-1.5	-1.2	-0.1	-1.1	-2.1	-1.7	0.3	-1.3	-1.3
Arm predicted mass (left)	0.6	2.8	5.0	-2.0	2.2	-0.9	-0.6	-0.6	-2.2	-2.0	-1.8	-2.0	-2.1	-1.7	-1.9	-1.1	-1.8	-2.1	-1.5	-0.6	-2.0	-1.7
Neuroticism (Nagel 2018)	0.5	1.1	2.5	1.1	-1.2	0.7	1.4	0.5	1.0	0.8	1.3	1.6	1.0	0.8	1.0	-0.6	1.4	1.3	1.3	0.0	1.1	0.9
Verbal and Numeric Reasoning (VNR)	0.5	1.2	2.5	1.2	-0.9	1.6	1.0	1.5	1.2	1.1	1.3	1.4	0.9	1.4	1.1	0.5	0.8	1.3	0.8	-0.2	1.0	0.9
Allergy or Eczema	0.5	1.2	3.7	1.0	-0.9	1.2	1.9	1.3	0.5	0.9	0.7	0.2	1.0	1.1	1.1	1.4	0.8	0.6	1.6	1.5	1.1	1.4
Relative age of first facial hair	0.5	1.0	3.9	-1.3	1.0	-2.0	-0.8	-0.9	-0.3	-1.6	-0.8	-0.8	-1.2	-1.0	-1.1	-0.9	-0.6	-1.1	-0.8	-0.3	-1.1	-0.9
High blood pressure	0.5	1.4	4.0	1.1	-1.1	1.2	-0.3	0.9	1.1	1.2	1.6	1.7	1.2	1.4	1.1	0.0	0.9	2.0	1.4	-0.6	1.2	1.1
Hayfever, allergic rhinitis or eczema	0.5	1.2	3.7	1.0	-1.0	1.5	1.9	1.0	0.4	0.9	0.9	0.4	1.1	1.0	1.0	1.2	0.9	0.8	1.2	1.5	1.1	1.4
Hayfever/allergic rhinitis (self-reported)	0.5	0.7	2.4	-0.7	0.6	-0.7	-0.1	-1.2	-0.5	-0.7	-1.4	-1.1	-0.7	-1.2	-0.6	-0.4	-0.4	-1.5	-0.5	0.4	-0.6	-0.8
Happiness	0.5	0.6	3.1	0.7	-0.6	1.8	1.3	-0.7	-0.0	0.7	0.0	-0.2	0.9	0.1	0.7	0.7	0.3	0.1	1.0	1.0	0.8	0.9
Medication: Ibuprofen (e.g. Nurofen)	0.5	0.7	2.5	-0.8	0.8	-0.3	0.8	-0.3	-0.7	-0.8	-0.9	-1.6	-0.9	-0.6	-0.8	0.7	-1.0	-1.3	-0.8	0.9	-0.9	-0.4
Pulse wave Arterial Stiffness index	0.5	0.6	1.8	-0.5	0.9	-1.3	-1.3	-0.2	-0.9	-0.9	-0.6	-0.4	-1.0	-0.3	-0.5	-0.7	-0.8	-0.7	-0.4	-0.8	-0.7	-0.8
Tense / ‘highly strung’	0.5	0.9	2.1	-1.2	1.0	-0.2	-0.8	-0.0	-0.7	-1.1	-0.9	-0.2	-1.1	-0.9	-1.1	-1.3	-0.9	-0.9	-1.0	-1.4	-1.1	-1.3
Loud music exposure frequency	0.5	0.5	3.3	0.6	-0.5	0.1	1.2	-0.8	-0.1	0.7	-0.1	-0.7	0.6	-0.2	0.5	0.9	0.5	-0.4	0.9	1.8	0.5	0.8
Qualifications: O levels/GCSEs or equivalent	0.5	0.7	2.2	-0.9	0.6	0.1	0.9	-0.3	-1.1	-0.6	-1.3	-1.5	-0.6	-0.8	-0.8	1.0	-1.1	-1.3	-0.7	0.6	-0.7	-0.4
Number of children fathered	0.5	0.6	1.5	-0.8	1.0	-0.9	-0.8	-0.0	0.4	-1.1	-0.6	-0.6	-1.0	-0.8	-0.9	-0.5	-0.7	-0.8	-1.2	-0.4	-0.9	-0.8
Qualifications: College or University degree	0.5	1.7	5.6	1.2	-1.4	0.5	2.4	1.2	1.8	1.3	1.2	0.8	1.3	1.1	1.2	1.3	1.3	0.8	1.3	1.7	1.3	1.5
Eye problems/disorders: None of the above	0.5	0.5	1.8	0.8	-0.8	0.9	0.1	0.0	1.4	0.8	0.7	0.9	0.9	0.6	0.8	0.3	0.5	1.0	0.6	-0.2	0.8	0.7
Age at last live birth	0.5	0.7	3.0	0.8	-0.7	0.7	1.4	0.1	0.8	0.6	-0.0	-0.3	0.6	0.5	0.8	1.7	0.2	-0.2	0.9	1.7	0.7	1.0
Qualifications: NVQ or HND or HNC or equivalent	0.5	0.7	2.7	0.7	-0.8	0.6	1.3	0.4	0.5	0.6	0.3	-0.4	0.7	0.5	0.8	1.6	0.4	0.3	0.7	1.6	0.8	1.0
Whole body fat-free mass	0.5	2.6	4.6	-1.9	2.1	-0.9	-0.6	-0.8	-1.9	-1.9	-1.8	-1.9	-2.0	-1.7	-1.8	-1.0	-1.7	-2.1	-1.6	-0.5	-1.9	-1.7
Whole body water mass	0.5	2.6	4.7	-1.9	2.2	-0.9	-0.7	-0.8	-1.9	-2.0	-1.7	-1.8	-2.1	-1.7	-1.9	-1.1	-1.6	-2.1	-1.6	-0.5	-2.0	-1.7
Illnesses of father: High blood pressure	0.5	0.6	1.3	1.1	-0.8	0.0	0.8	0.3	0.9	1.1	0.9	1.1	0.9	0.9	1.0	0.1	0.8	0.8	0.6	0.1	0.9	0.7
Alcohol drinker status: Never	0.5	0.6	2.3	0.9	-0.6	0.2	-0.7	0.0	0.0	0.7	0.9	1.5	0.6	0.6	0.8	-1.3	1.2	1.2	0.0	-0.9	0.7	0.0
Average weekly beer plus cider intake	0.5	0.7	2.3	-0.7	0.8	0.8	-0.2	-1.0	-0.8	-0.5	-1.2	-1.5	-0.7	-0.8	-0.7	0.6	-1.3	-1.1	-1.2	0.2	-0.7	-0.7
Age started oral contraceptive pill	0.5	0.7	3.0	0.8	-0.6	-0.1	1.2	0.6	0.1	0.5	0.3	-0.4	0.6	0.7	0.7	1.7	0.2	0.1	1.3	1.6	0.7	1.1
Heart disease (siblings)	0.5	0.6	1.8	0.6	-0.5	-0.1	-0.6	0.1	0.8	0.3	0.9	1.3	0.4	0.8	0.8	-1.1	1.0	1.0	1.1	-0.7	0.7	0.4
Ovarian Cancer	0.4	0.5	3.1	-0.4	0.6	-0.5	-1.1	-0.5	0.2	-0.4	-0.1	0.8	-0.5	-0.5	-0.3	-1.8	0.3	-0.1	0.4	-1.6	-0.4	-0.8
Other serious medical condition/disability diagnosed by doctor	0.4	0.5	2.0	-0.7	0.8	-1.0	-0.7	-0.4	-0.7	-0.8	-0.2	-0.0	-0.8	-0.3	-0.6	-0.9	-0.7	0.0	-0.7	-1.4	-0.7	-0.8
Diabetes (mother)	0.4	0.5	2.8	0.6	-0.4	1.0	1.1	-0.7	-0.1	0.8	-0.4	-0.8	0.6	-0.2	0.4	1.7	-0.1	-0.2	-0.1	1.3	0.4	0.4
Current tobacco smoking	0.4	0.7	4.4	-0.5	0.7	0.3	-2.1	-0.4	-0.7	-0.5	0.1	0.6	-0.6	-0.2	-0.4	-1.5	-0.1	0.1	-1.1	-1.5	-0.5	-1.0
Age when periods started (menarche)	0.4	1.1	6.3	1.0	-0.9	-0.1	1.8	-0.3	0.8	0.9	0.5	-0.3	1.0	0.3	0.8	1.4	1.1	0.0	1.0	2.5	0.9	1.3
Sitting height	0.4	2.7	5.9	1.7	-1.4	1.6	2.4	2.2	1.4	1.5	1.7	1.0	1.6	1.8	1.6	1.7	1.4	1.4	1.7	1.7	1.6	2.1
Hair/balding pattern: Pattern 2	0.4	0.5	1.4	-0.6	0.7	-0.1	-0.5	-1.2	-0.5	-0.5	-0.9	-0.9	-0.5	-0.8	-0.7	0.0	-0.8	-0.7	-1.0	-0.4	-0.6	-0.7
Impedance of arm (left)	0.4	1.8	3.9	1.4	-1.7	-0.0	1.4	0.5	2.0	1.3	1.5	1.1	1.6	1.2	1.3	1.1	1.2	1.6	1.6	0.8	1.4	1.7
Exposure to tobacco smoke at home	0.4	0.4	1.5	0.8	-0.7	1.2	-0.1	-0.1	0.8	0.7	0.6	0.7	0.7	0.8	0.9	0.5	0.6	0.7	0.1	0.1	0.8	0.4
Forced vital capacity (FVC), Best measure	0.4	1.4	4.4	1.3	-1.2	1.7	0.8	0.2	0.6	1.2	1.4	2.1	1.3	1.0	1.2	-0.4	1.6	1.5	1.1	-0.3	1.2	0.8
Exposure to tobacco smoke outside home	0.4	0.6	1.0	0.8	-0.9	0.7	0.8	-0.3	0.6	1.0	0.8	0.6	0.9	0.7	0.8	0.2	0.9	0.9	1.0	0.5	0.9	0.8
Wheeze or whistling in the chest in last year	0.4	0.6	3.6	-0.3	0.5	-0.0	-1.9	-0.5	-1.9	-0.4	-0.0	0.2	-0.5	-0.1	-0.2	-1.2	-0.5	0.4	-0.3	-1.5	-0.3	-0.7
Mean time to correctly identify matches	0.4	0.9	4.7	-0.3	0.3	-1.1	-2.2	0.1	-1.1	-0.3	0.2	1.1	-0.4	-0.0	-0.3	-1.6	-0.2	0.5	-0.1	-2.1	-0.3	-0.8
Eye problems/disorders: Glaucoma	0.4	0.5	1.0	-0.7	0.4	-1.0	-0.3	-0.8	-0.7	-0.6	-0.8	-0.8	-0.6	-1.0	-0.7	-0.5	-0.5	-0.7	-1.0	-0.0	-0.7	-0.8
Schizophrenia (2018)	0.3	0.6	1.8	-0.7	0.8	-1.3	-0.2	-0.5	-0.1	-0.9	-0.8	-0.7	-0.9	-0.9	-0.9	-0.3	-0.3	-1.1	-1.0	0.2	-0.9	-0.8
Reaction Time	0.3	0.6	3.0	-0.2	0.1	-1.0	-1.7	-0.4	-0.9	-0.3	0.1	0.9	-0.3	-0.1	-0.2	-1.4	-0.1	0.3	-0.3	-1.6	-0.2	-0.7
Bipolar Disorder (2011)	0.3	0.3	0.9	0.6	-0.6	0.5	-0.1	-0.9	0.0	0.0	0.3	0.8	0.7	0.1	0.5	-0.4	0.5	0.9	0.2	-0.7	0.6	0.2
Body Mass Index (BMI) (2010)	0.3	0.4	2.3	0.6	-0.6	1.5	0.2	0.2	-0.5	0.7	0.5	0.3	0.7	0.7	0.6	0.9	0.2	0.8	0.3	0.3	0.7	0.6
HDL Cholesterol	0.3	0.5	2.7	0.3	-0.5	-0.5	1.1	-0.1	1.2	0.3	0.0	-0.6	0.5	-0.1	0.3	0.8	0.5	-0.2	0.8	1.6	0.4	0.8
Ulcerative Colitis	0.3	0.4	1.6	1.0	-0.7	1.3	0.4	-0.4	1.2	0.8	0.3	0.8	0.5	0.2	0.7	0.1	0.7	0.3	0.7	-0.2	0.6	0.3
Smoking Status	0.3	0.8	2.4	0.8	-0.9	1.4	-0.6	0.8	0.4	0.9	1.3	1.2	0.9	1.2	0.8	0.3	0.7	1.5	0.5	-0.3	0.8	0.6
Sensitivity / hurt feelings	0.3	0.5	2.8	0.3	-0.3	-0.0	0.1	0.1	0.5	0.2	0.7	1.7	0.4	0.3	0.3	-1.7	1.0	0.8	0.4	-1.3	0.3	-0.1
Medication: Metformin	0.3	0.5	2.8	0.4	-0.6	0.9	1.7	0.5	0.4	0.7	0.3	-0.3	0.5	0.2	0.4	1.0	0.2	0.3	0.9	1.0	0.4	0.8
Townsend deprivation index at recruitment	0.3	0.4	1.9	0.8	-0.8	0.9	-0.8	0.0	0.1	0.9	0.7	0.8	0.8	0.6	0.7	0.1	0.3	1.4	-0.1	-0.7	0.7	0.2
Alcohol usually taken with meals	0.3	0.6	2.4	0.3	-0.5	-0.5	1.3	1.2	0.2	0.2	0.5	-0.1	0.5	0.6	0.3	1.0	0.2	0.2	1.5	1.1	0.4	1.2
Had other major operations	0.3	0.3	1.0	0.4	-0.6	0.8	0.0	0.7	0.3	0.2	0.7	0.7	0.3	1.0	0.5	0.8	0.1	0.9	0.4	-0.3	0.5	0.4
Forced vital capacity (FVC)	0.3	1.3	3.7	1.3	-1.1	1.5	0.9	0.7	0.7	1.4	1.5	1.9	1.3	1.1	1.1	0.1	1.4	1.5	0.9	-0.1	1.1	0.9
Qualifications: None of the above	0.3	0.7	4.1	-0.4	0.5	-0.5	-1.8	-0.8	-0.7	-0.4	0.1	0.6	-0.3	-0.4	-0.5	-1.7	-0.2	0.6	-0.3	-2.0	-0.4	-0.8
Mouth/teeth dental problems	0.3	0.5	1.1	0.7	-0.7	0.7	0.8	1.0	0.9	0.8	0.4	0.3	0.8	0.8	0.7	1.0	0.5	0.4	0.6	0.7	0.7	0.9
Allergy	0.3	0.8	2.9	-0.6	0.8	-0.9	-1.7	-0.5	0.6	-0.5	-0.3	0.4	-0.7	-0.7	-0.7	-1.4	-0.3	-0.3	-1.1	-1.7	-0.8	-1.1
Alcohol intake versus 10 years previously	0.3	0.5	2.1	0.4	-0.8	0.5	0.4	0.2	0.0	0.5	0.9	1.4	0.8	0.3	0.4	-0.8	1.0	1.0	1.0	-0.4	0.6	0.5
Frequency of tiredness / lethargy in last 2 weeks	0.3	0.4	3.2	-0.4	0.3	0.9	-0.6	0.3	-0.4	-0.3	0.3	0.7	-0.3	-0.0	-0.4	-1.3	-0.3	0.6	0.1	-1.8	-0.4	-0.4
Serious illness, injury or assault of a close relative in last 2 years	0.3	0.4	2.4	0.1	-0.5	0.7	0.7	-0.3	1.6	0.4	0.1	-0.4	0.4	-0.3	-0.1	0.9	0.4	-0.1	-0.1	1.3	0.1	0.6
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.5	2.0	-0.9	0.6	-0.2	-0.7	-0.4	-1.4	-0.8	-0.9	-0.8	-0.8	-0.7	-0.8	-0.2	-0.9	-0.7	-0.3	-0.5	-0.8	-0.7
Peak expiratory flow (PEF)	0.3	0.6	1.2	-0.8	0.8	-0.8	-0.9	-1.0	-0.5	-0.7	-0.8	-0.2	-0.8	-1.1	-0.9	-1.1	-0.6	-0.5	-0.6	-1.1	-0.9	-0.9
Pulse wave reflection index	0.3	0.3	1.8	0.1	0.1	-1.3	-0.0	-0.7	-0.4	-0.1	-0.8	-1.0	-0.2	-0.3	0.1	0.4	-0.1	-1.1	-0.1	1.1	0.0	-0.1
Ever highly irritable/argumentative for 2 days	0.3	0.3	1.0	-0.6	0.7	-0.3	0.1	-0.7	-0.6	-0.4	-0.7	-1.0	-0.6	-0.6	-0.5	0.1	-0.9	-0.7	0.3	0.0	-0.5	-0.3
Medication for cholesterol, blood pressure or diabetes	0.3	0.4	2.1	0.0	-0.1	-0.6	1.2	-1.0	0.5	0.1	-0.6	-1.0	0.0	-0.5	0.1	0.5	0.2	-0.9	-0.4	1.5	0.1	-0.1
Mouth/teeth dental problems: Loose teeth	0.3	0.4	1.3	0.6	-0.4	-0.4	0.5	0.8	0.2	0.5	0.7	0.9	0.5	0.6	0.6	-0.2	0.8	0.6	1.1	0.1	0.5	0.5
Neck or shoulder pain in last month	0.3	0.4	0.8	-0.8	0.9	-0.5	-0.5	-0.9	-0.2	-0.7	-0.5	-0.6	-0.7	-0.8	-0.7	-0.6	-0.4	-0.7	-0.5	0.0	-0.7	-0.5
Medication: Ibuprofen	0.3	0.4	1.3	-0.6	0.6	-0.1	0.7	0.1	-0.8	-0.7	-0.6	-1.1	-0.7	-0.4	-0.6	0.6	-0.8	-1.0	-0.3	0.7	-0.7	-0.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.3	0.3	2.4	0.1	0.0	0.8	-0.3	1.5	0.7	0.1	0.4	0.8	-0.1	0.6	0.0	0.0	-0.2	0.4	-0.3	-1.0	-0.1	-0.1
Illnesses of siblings: Diabetes	0.3	0.4	1.3	0.2	-0.5	1.0	0.4	0.0	-0.0	0.5	0.9	1.1	0.7	0.4	0.2	-0.5	0.9	1.1	0.8	-0.3	0.4	0.5
Diabetes diagnosed by doctor	0.3	0.5	1.2	0.4	-0.8	0.7	1.1	0.6	-0.9	0.5	0.8	0.4	0.7	0.7	0.4	0.6	0.4	1.0	0.7	0.4	0.5	0.7
Smoking status: Current	0.3	0.4	2.9	-0.2	0.4	0.6	-1.7	-0.2	-0.6	-0.2	0.4	0.7	-0.3	0.2	-0.2	-1.2	0.1	0.5	-0.7	-1.2	-0.2	-0.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.3	0.5	1.5	0.8	-0.8	1.2	0.7	-0.0	0.8	0.8	0.6	1.2	0.9	0.3	0.6	-0.4	1.1	0.9	0.7	-0.3	0.7	0.5
Financial situation satisfaction	0.3	0.4	2.7	-0.2	0.3	0.4	0.3	-1.6	-1.2	-0.2	-0.8	-0.9	-0.2	-0.6	-0.1	0.1	-0.5	-0.7	-0.2	0.4	-0.2	-0.3
Number of operations (self-reported)	0.3	0.4	2.3	-0.5	0.6	-0.2	-1.2	0.3	-0.2	-0.5	0.0	0.7	-0.7	-0.1	-0.4	-1.0	-0.3	0.2	-0.6	-1.5	-0.5	-0.9
Irritability	0.3	0.5	1.5	-1.0	0.8	-0.2	-0.5	-0.7	-0.4	-0.8	-0.9	-0.9	-0.8	-1.0	-0.9	-0.5	-0.6	-1.2	-0.4	0.1	-0.9	-0.6
Ever had prostate specific antigen (PSA) test	0.3	0.4	2.1	0.4	-0.3	0.2	0.4	1.2	1.4	0.5	0.9	0.7	0.3	0.8	0.6	0.2	0.4	0.7	0.2	-0.1	0.5	0.4
Depressed Affect (Nagel 2018)	0.2	0.4	1.3	0.5	-0.4	0.4	0.8	0.5	0.2	0.5	0.7	1.1	0.4	0.3	0.3	-0.9	0.8	0.7	0.9	-0.4	0.3	0.3
Depression (Nagel 2018)	0.2	0.4	3.1	0.3	-0.1	-0.1	1.8	-1.2	0.3	0.2	-0.1	-0.3	0.3	-0.3	0.5	-0.5	0.6	-0.3	0.5	0.8	0.5	0.3
Worry (Nagel 2018)	0.2	0.5	1.6	0.6	-0.3	0.4	0.2	-0.6	0.4	0.7	0.6	1.3	0.7	0.2	0.6	-1.3	0.9	0.9	0.5	-0.7	0.6	0.1
Crohns Disease (2017)	0.2	0.5	2.0	0.8	-0.5	0.0	0.1	0.6	1.4	0.6	0.8	1.0	0.6	0.8	0.7	0.1	0.9	0.7	0.7	0.0	0.7	0.6
Ulcerative Colitis (UC)	0.2	0.3	4.2	0.8	-0.2	0.4	0.2	-0.0	2.0	0.4	0.2	0.4	0.1	-0.0	0.5	0.1	0.2	0.1	0.4	-0.1	0.3	0.2
Coronary Artery Disease (CAD)	0.2	0.2	1.6	-0.1	0.1	-1.3	0.3	0.3	0.8	0.0	0.2	0.5	-0.5	-0.2	-0.3	-0.9	0.5	-0.4	0.1	0.1	-0.3	-0.3
Crohns Disease (2012)	0.2	0.3	1.0	0.6	-0.6	0.4	-0.3	0.3	0.3	0.6	0.6	1.0	0.5	0.7	0.8	-0.2	0.7	0.6	0.3	-0.4	0.7	0.2
Neuroticism (2016)	0.2	0.4	1.1	0.3	-0.6	0.4	0.0	1.0	0.3	0.6	0.7	0.7	0.6	1.0	0.7	0.1	0.5	0.7	0.8	0.0	0.7	0.6
Height	0.2	3.2	7.7	1.9	-1.8	1.1	2.8	1.4	1.7	1.7	1.8	1.2	1.8	2.0	1.9	1.4	2.0	1.4	2.0	2.0	1.9	2.1
Systolic Blood Pressure	0.2	1.1	3.6	1.2	-0.7	-0.5	-0.8	0.4	0.6	1.2	1.6	1.9	0.8	1.8	1.2	0.1	0.8	1.9	0.2	-1.0	1.1	0.6
Type 2 Diabetes (T2D) (2018)	0.2	0.3	1.0	0.1	-0.1	1.0	0.6	0.9	-0.2	0.2	0.9	0.9	0.4	0.5	-0.0	-0.1	0.4	0.9	0.4	-0.4	0.1	0.4
Number of treatments/medications taken	0.2	0.4	1.7	0.1	-0.2	0.6	-0.2	0.9	-0.2	0.1	1.0	1.3	0.2	0.6	-0.1	-0.7	0.4	1.1	0.8	-1.0	-0.0	0.3
Pack years adult smoking proportion	0.2	0.2	1.4	0.2	-0.3	1.2	0.9	0.4	-0.8	0.2	-0.0	-0.4	0.1	0.2	0.1	0.9	-0.3	-0.1	0.5	0.7	0.1	0.4
Taking other prescription medications	0.2	0.3	0.8	-0.9	0.6	-0.6	-0.7	0.1	-0.7	-0.9	-0.2	-0.4	-0.6	-0.4	-0.9	-0.1	-0.9	0.1	-0.2	-0.7	-0.8	-0.2
Medication: Ramipril	0.2	0.2	1.3	0.2	-0.2	1.1	-0.8	0.7	0.0	0.1	0.5	0.7	0.1	0.5	0.1	-0.3	0.1	0.7	0.2	-0.8	0.1	0.1
Neuroticism score	0.2	0.5	2.6	0.3	-0.3	0.6	0.4	0.5	0.5	0.4	0.7	1.4	0.4	0.4	0.3	-1.6	0.9	0.8	0.5	-1.0	0.3	0.0
Trunk fat-free mass	0.2	1.4	2.7	-1.3	1.6	-0.6	-0.2	-0.3	-1.7	-1.4	-1.2	-1.5	-1.5	-1.1	-1.3	-0.6	-1.2	-1.6	-1.3	-0.1	-1.4	-1.3
Forced expiratory volume in 1-second (FEV1)	0.2	0.8	2.7	0.9	-0.9	1.4	0.6	-0.0	0.8	1.1	0.9	1.6	1.0	0.5	0.8	-0.4	1.2	1.1	0.9	-0.4	0.8	0.6
Asthma	0.2	0.3	3.2	-0.4	0.0	-0.3	0.2	-0.7	-1.8	-0.4	-0.7	-0.9	-0.3	-0.3	-0.1	0.0	-0.5	-0.6	0.0	0.4	-0.1	-0.2
Medication: Lansoprazole	0.2	0.2	1.1	0.3	-0.4	1.0	-0.0	0.6	-0.5	0.5	0.4	0.4	0.5	0.6	0.3	0.6	-0.2	1.0	-0.3	-0.6	0.3	0.1
Prospective memory result	0.2	0.2	0.9	0.4	-0.6	0.8	0.1	0.2	-1.0	0.3	0.4	0.4	0.5	0.5	0.4	0.4	0.5	0.5	0.5	0.3	0.4	0.4
Lung cancer (father)	0.2	0.2	1.0	-0.0	-0.2	0.4	0.8	0.3	0.6	0.0	-0.3	-1.0	0.1	-0.1	-0.0	0.9	-0.4	-0.4	-0.4	1.0	0.0	0.3
Forced expiratory volume in 1-second (FEV1), Best measure	0.2	0.7	2.3	0.8	-0.7	1.4	0.4	-0.5	0.6	0.8	0.8	1.5	0.8	0.3	0.7	-0.7	1.1	0.9	0.8	-0.5	0.7	0.4
Trunk predicted mass	0.2	1.4	2.6	-1.3	1.6	-0.6	-0.2	-0.2	-1.6	-1.4	-1.2	-1.5	-1.5	-1.1	-1.3	-0.6	-1.2	-1.5	-1.3	-0.1	-1.4	-1.3
Mouth/teeth dental problems: Bleeding gums	0.2	0.3	1.2	0.3	-0.5	-0.2	0.4	-0.3	-0.3	0.2	0.1	-0.5	0.3	0.4	0.4	1.0	0.2	0.1	0.9	1.1	0.4	0.7
Headache pain in last month	0.2	0.3	1.5	0.3	-0.5	1.0	1.2	-0.0	0.2	0.5	0.3	0.4	0.6	0.1	0.3	-0.3	0.5	0.6	0.5	0.0	0.4	0.5
Chronic bronchitis/emphysema (mother)	0.2	0.3	2.8	0.5	-0.2	-0.0	0.7	-1.7	-0.0	0.5	-0.3	-0.6	0.2	-0.4	0.4	0.4	-0.2	-0.1	0.2	0.6	0.3	0.1
High blood pressure (siblings)	0.2	0.2	0.6	0.4	-0.8	0.0	0.7	-0.8	0.4	0.5	0.3	0.1	0.6	0.5	0.5	0.7	0.3	0.5	0.2	0.4	0.6	0.6
Worry too long after embarrassment	0.2	0.3	1.0	0.5	-0.5	-0.1	0.9	0.5	1.0	0.5	0.5	0.5	0.4	0.6	0.6	0.1	0.6	0.4	0.9	0.4	0.5	0.7
Shortness of breath walking on level ground	0.2	0.3	2.1	0.4	-0.3	0.4	0.1	0.1	0.2	0.2	0.5	0.7	0.3	0.4	0.5	-0.6	0.7	0.4	1.4	-0.1	0.4	0.5
Medication: Blood pressure	0.2	0.4	1.6	0.2	-0.1	0.7	-1.2	1.0	0.2	0.0	0.8	1.2	0.1	0.6	0.1	-0.5	0.1	1.0	0.6	-1.2	0.1	0.3
Medication: Allopurinol	0.2	0.3	1.8	-0.5	0.3	-0.2	-1.3	-0.0	0.1	-0.4	0.1	0.3	-0.2	-0.4	-0.5	-1.0	-0.2	0.4	-0.0	-1.2	-0.4	-0.3
Alcohol intake frequency.	0.2	0.6	3.2	-0.4	0.2	-0.6	-0.9	-1.8	-1.4	-0.4	-0.5	-0.1	-0.2	-1.0	-0.5	-1.3	-0.1	0.1	-0.1	-0.9	-0.4	-0.7
Overall health rating	0.2	0.5	2.8	-0.5	0.6	0.6	-0.8	-0.7	-1.7	-0.5	-0.1	0.1	-0.6	-0.3	-0.5	-1.1	-0.7	0.3	-0.1	-1.5	-0.6	-0.6
Medication: Aspirin	0.2	0.2	1.2	-0.7	0.1	-0.4	0.6	1.1	-1.1	-0.5	0.4	-0.1	-0.1	0.2	-0.7	0.0	-0.2	0.3	0.4	0.1	-0.5	0.2
Qualifications: nursing, teaching	0.2	0.3	2.1	-0.0	-0.1	-0.3	1.5	-0.6	0.3	-0.0	-0.5	-0.6	0.1	-0.4	-0.1	0.6	-0.1	-0.7	0.2	1.0	0.0	0.3
Commuting to job workplace: Walk	0.2	0.2	0.8	-0.3	0.0	0.0	-0.2	-0.4	0.3	-0.2	-0.4	-0.9	0.0	-0.5	-0.3	0.7	-0.3	-0.4	-0.7	0.9	-0.2	0.1
Osteoarthritis (self-reported)	0.2	0.3	0.7	-0.9	0.5	0.3	0.1	-0.3	-0.7	-0.6	-0.5	-0.6	-0.5	-0.5	-0.8	-0.3	-0.6	-0.4	-0.7	-0.2	-0.7	-0.5
Medication: Aspirin	0.2	0.2	0.7	-0.3	-0.4	-0.0	0.9	0.8	-0.7	-0.1	0.7	0.3	0.3	0.3	-0.4	-0.1	0.4	0.6	0.7	0.4	-0.1	0.5
Medication: Gliclazide	0.2	0.3	2.0	-0.5	0.4	-0.2	0.5	-0.6	-1.4	-0.6	-0.3	-0.1	-0.4	-0.5	-0.4	-0.5	-0.4	-0.2	0.4	-0.3	-0.4	-0.3
Illnesses of father: None of the above (group 1)	0.2	0.2	1.2	-0.2	-0.2	0.8	0.8	0.8	-0.5	-0.0	0.0	-0.4	0.1	0.3	-0.1	1.1	-0.4	0.1	0.5	0.3	-0.0	0.4
Mother’s age at death	0.2	0.3	1.5	0.4	-0.4	0.7	0.5	-1.0	-0.1	0.4	-0.4	-0.6	0.3	-0.1	0.3	1.2	-0.2	-0.2	-0.8	0.8	0.3	0.1
Tinnitus: Yes, now most or all of the time	0.2	0.3	0.7	0.6	-0.4	0.1	0.7	0.0	0.5	0.4	0.7	0.6	0.4	0.4	0.6	-0.7	0.9	0.5	0.5	0.4	0.5	0.4
Commuting to job workplace: Public transport	0.2	0.2	0.9	-0.4	0.7	-0.4	-0.8	0.3	0.3	-0.4	0.1	0.4	-0.5	-0.2	-0.6	-0.9	-0.0	-0.2	-0.3	-0.5	-0.6	-0.4
Pain type(s) experienced in last month: Hip pain	0.2	0.3	1.4	-0.5	0.5	-0.5	0.5	-0.3	0.0	-0.4	-0.6	-1.2	-0.6	-0.5	-0.5	0.4	-0.5	-0.8	-0.1	0.7	-0.5	-0.2
Commuting to job workplace: Cycle	0.2	0.2	0.5	0.6	-0.4	0.1	0.4	-0.6	0.3	0.5	0.2	0.6	0.5	0.2	0.6	-0.3	0.7	0.4	0.2	-0.2	0.6	0.0
Cholesterol lowering medication	0.2	0.3	1.0	0.5	-0.6	0.6	0.5	-0.4	-0.4	0.3	0.1	-0.4	0.5	0.3	0.4	1.0	-0.0	0.2	0.8	0.9	0.4	0.8
Pain experienced in last month	0.2	0.3	1.8	0.5	-0.3	-0.1	-1.4	0.7	-0.5	0.2	0.5	0.9	0.1	0.9	0.5	0.1	-0.2	0.6	0.1	-0.9	0.4	-0.1
Pack years of smoking	0.2	0.4	1.4	0.5	-0.5	1.1	1.2	0.6	-0.5	0.4	0.2	-0.2	0.3	0.4	0.3	1.0	-0.0	0.1	0.8	0.9	0.3	0.6
Bipolar Disorder (2018)	0.1	0.2	0.5	0.7	-0.6	-0.1	0.4	-0.6	0.5	0.7	0.1	0.1	0.6	-0.1	0.5	0.1	0.6	0.3	0.4	0.5	0.5	0.4
Bipolar Disorder or Schizophrenia	0.1	0.2	1.3	-0.2	0.2	-1.1	0.0	-0.8	0.2	-0.3	-0.6	-0.5	-0.3	-0.8	-0.4	-0.1	0.1	-0.7	-0.4	0.5	-0.4	-0.3
LDL Cholesterol	0.1	0.2	1.3	-0.3	0.1	-0.5	0.7	0.9	1.1	-0.2	0.2	-0.2	-0.1	0.1	-0.3	0.6	0.2	-0.1	0.5	0.7	-0.2	0.5
Rheumatoid Arthritis	0.1	0.2	1.0	-0.4	0.4	-1.0	-0.3	-0.5	0.3	-0.4	-0.3	-0.0	-0.3	-0.4	-0.3	-0.6	0.3	-0.6	-0.4	0.1	-0.3	-0.4
Schizophrenia (2014)	0.1	0.1	1.0	-0.1	0.2	-1.0	0.4	-0.5	0.3	-0.3	-0.3	-0.1	-0.2	-0.3	-0.3	-0.2	0.3	-0.6	-0.4	0.4	-0.3	-0.3
Blood Red Count	0.1	1.0	5.0	-0.3	0.5	-1.9	-2.2	-0.7	-1.0	-0.5	0.3	1.0	-0.6	0.2	0.1	-1.7	-0.2	0.6	-0.1	-2.1	-0.1	-0.7
Cardiovascular Disease	0.1	0.5	2.0	0.7	-0.5	0.4	-0.2	0.6	0.1	0.8	1.1	0.9	0.7	0.9	0.6	0.6	0.2	1.4	0.5	-0.4	0.5	0.7
Lung FEV1/FVC ratio	0.1	0.6	1.9	-0.9	0.5	0.8	-0.4	-0.7	0.2	-0.7	-1.4	-1.1	-0.6	-1.2	-0.9	-0.0	-1.1	-1.1	-0.9	-0.4	-0.8	-0.6
Neuroticism	0.1	0.2	1.1	0.4	-0.3	0.2	0.8	-0.6	0.2	0.5	0.4	0.8	0.4	-0.1	0.3	-1.0	0.6	0.5	0.5	-0.4	0.3	0.1
Hair Pigment	0.1	1.5	4.5	1.3	-1.3	2.1	1.2	0.8	1.4	1.3	1.1	1.0	1.3	1.2	1.3	1.2	1.2	1.1	0.8	0.9	1.3	1.1
Frequency of depressed mood in last 2 weeks	0.1	0.2	1.3	-0.1	0.1	-0.1	0.5	-1.1	-0.6	-0.0	-0.3	-0.2	-0.1	-0.3	0.0	-0.9	-0.0	-0.2	-0.2	-0.3	-0.0	-0.3
Ever used hormone-replacement therapy (HRT)	0.1	0.1	0.4	0.1	0.0	0.6	-0.5	0.4	-0.3	-0.2	0.1	0.4	-0.2	0.0	0.0	-0.3	-0.1	0.1	0.6	-0.5	-0.1	-0.1
Systolic blood pressure, automated reading	0.1	0.3	1.6	0.0	0.5	-1.1	-1.3	-0.6	-0.3	-0.0	0.1	0.2	-0.3	0.3	0.1	-0.2	-0.6	0.4	-0.2	-1.1	-0.0	-0.3
Vitamin and mineral supplements	0.1	0.2	1.0	-0.5	0.2	0.2	-1.0	0.7	-0.5	-0.4	-0.1	0.3	-0.2	-0.1	-0.4	-0.4	-0.3	-0.0	-0.4	-0.9	-0.3	-0.4
Supplements: Zinc	0.1	0.1	0.6	-0.4	0.2	0.5	0.3	0.7	0.1	-0.3	-0.3	-0.3	-0.2	0.1	-0.3	0.8	-0.3	-0.4	-0.5	0.3	-0.2	-0.0
Diabetes (father)	0.1	0.1	0.4	0.4	-0.4	-0.4	-0.3	-0.6	0.6	0.4	0.3	0.1	0.3	-0.2	0.3	-0.2	0.6	0.2	0.5	0.4	0.3	0.3
Hand grip strength (right)	0.1	0.4	1.0	-0.6	0.6	0.2	-0.4	-0.7	-0.4	-0.7	-1.0	-0.9	-0.6	-0.9	-0.6	-0.3	-0.8	-1.0	-0.5	-0.2	-0.6	-0.5
Average weekly fortified wine intake	0.1	0.2	0.8	-0.3	0.3	0.1	-0.9	-0.6	-0.4	-0.5	-0.4	-0.6	-0.4	-0.3	-0.2	-0.1	-0.6	-0.2	-0.1	-0.2	-0.3	-0.2
Maternal smoking around birth	0.1	0.1	0.6	0.4	-0.3	0.0	0.6	-0.1	0.2	0.2	0.0	-0.3	0.1	0.1	0.2	0.6	-0.2	0.1	0.8	0.5	0.1	0.6
Fed-up feelings	0.1	0.2	1.6	0.3	-0.4	1.3	0.8	0.3	-0.1	0.5	0.3	0.3	0.5	0.2	0.3	-0.2	0.4	0.4	0.4	0.1	0.3	0.4
Frequency of unenthusiasm / disinterest in last 2 weeks	0.1	0.1	1.0	-0.1	0.2	0.0	0.8	0.1	-0.4	-0.2	0.2	0.2	0.0	-0.1	-0.1	-1.0	0.0	0.2	0.2	-0.5	-0.0	-0.0
Stomach or abdominal pain in last month	0.1	0.2	0.8	-0.1	-0.2	-0.1	-0.3	0.4	-0.3	0.2	0.4	0.5	0.3	0.2	0.0	-0.6	0.0	0.9	-0.2	-0.9	0.1	-0.0
Past tobacco smoking	0.1	0.1	0.6	-0.2	0.4	-0.5	0.1	0.0	-0.1	-0.4	-0.2	0.1	-0.3	-0.2	-0.2	-0.8	-0.1	-0.3	-0.1	-0.5	-0.2	-0.3
Nervous feelings	0.1	0.1	0.9	0.2	-0.3	-0.2	0.9	0.2	0.4	0.4	0.3	0.2	0.4	0.1	0.2	-0.4	0.4	0.2	0.3	0.2	0.2	0.3
Hearing difficulty/problems with background noise	0.1	0.2	0.7	0.1	0.1	0.3	0.6	0.1	0.8	0.1	0.7	0.7	0.2	0.1	-0.0	-0.5	0.4	0.6	0.2	-0.2	0.0	0.2
Hair/balding pattern: Pattern 3	0.1	0.1	0.6	0.1	0.1	-0.8	-0.2	-0.6	0.4	0.1	-0.4	-0.0	-0.2	-0.3	0.0	-0.4	-0.2	-0.2	-0.6	-0.5	-0.1	-0.5
Noisy workplace	0.1	0.2	0.7	-0.2	0.6	-0.4	0.3	-0.5	-0.1	-0.2	-0.4	-0.8	-0.4	-0.4	-0.3	0.4	-0.9	-0.4	-0.5	0.0	-0.4	-0.3
Medication: Cholesterol lowering	0.1	0.1	0.6	-0.3	0.0	0.7	-0.5	0.3	-0.7	-0.2	-0.1	0.1	-0.1	-0.0	-0.4	-0.0	-0.5	0.3	0.2	-0.8	-0.2	0.0
Standing height	0.1	1.1	5.5	1.0	-0.8	0.4	2.3	0.9	1.0	0.9	0.9	0.2	0.9	0.9	0.9	1.1	0.9	0.6	1.1	1.8	0.9	1.4
Length of working week for main job	0.1	0.1	0.8	-0.1	0.3	-0.8	-0.4	-0.9	0.2	-0.2	-0.0	0.1	-0.3	-0.1	0.1	-0.7	0.0	-0.2	-0.4	-0.4	-0.0	-0.5
Breastfed as a baby	0.1	0.1	0.8	0.1	-0.1	-0.3	0.7	-0.0	-0.4	-0.0	-0.1	-0.6	0.0	0.1	0.2	0.9	-0.2	-0.3	-0.0	0.9	0.2	0.1
Medication: Paracetamol	0.1	0.2	1.2	-0.4	0.3	-0.1	0.0	-1.1	-0.0	-0.3	-0.3	-0.4	-0.2	-0.8	-0.5	-0.5	-0.2	-0.1	0.2	-0.1	-0.4	-0.1
Gout (self-reported)	0.1	0.1	0.6	-0.2	0.2	0.2	-0.8	0.1	0.5	0.0	-0.1	-0.1	0.0	-0.3	-0.2	-0.0	-0.3	0.1	-0.5	-0.4	-0.1	-0.1
Medication: Ventolin 100micrograms inhaler	0.1	0.2	0.5	0.3	-0.3	0.7	-0.2	0.6	-0.3	0.4	0.6	0.6	0.2	0.5	0.2	-0.2	0.1	0.7	0.2	-0.6	0.2	0.2
Seen a psychiatrist for nerves, anxiety, tension or depression	0.1	0.1	0.6	0.0	-0.1	-0.2	-0.2	-0.8	0.1	0.1	-0.4	-0.3	-0.1	-0.4	0.1	-0.0	-0.2	-0.4	0.2	0.0	0.0	-0.2
Emphysema/chronic bronchitis	0.1	0.1	0.5	0.1	-0.1	0.2	0.5	0.5	-0.7	0.1	0.3	-0.0	0.2	0.2	-0.1	0.4	-0.1	0.3	0.1	0.3	0.0	0.3
Medication for pain relief, constipation, heartburn	0.1	0.2	1.3	0.3	-0.1	-0.3	-1.2	-0.6	0.1	0.2	-0.3	0.4	0.0	-0.0	0.5	-0.3	0.1	-0.2	-0.6	-0.5	0.3	-0.4
Migraine (self-reported)	0.1	0.2	0.9	-0.1	-0.1	0.5	-0.4	0.1	0.6	-0.1	0.4	0.8	0.1	0.0	-0.0	-1.0	0.7	0.4	0.2	-0.5	0.0	-0.0
Medication: Seretide 50 evohaler	0.1	0.1	0.7	0.1	-0.2	0.3	-0.3	0.8	-0.7	0.1	0.2	0.0	0.1	0.5	0.3	-0.0	-0.0	0.2	0.9	0.0	0.2	0.3
Comparative height size at age 10	0.1	0.7	2.1	0.9	-0.3	0.9	0.7	1.4	0.4	0.6	1.0	1.1	0.5	1.1	0.9	-0.1	0.6	1.0	1.2	-0.2	0.8	0.7
Commuting to job workplace: Car/motor vehicle	0.1	0.1	0.6	0.3	-0.3	-0.2	0.6	-0.8	0.0	0.1	-0.1	-0.3	0.2	0.2	0.5	0.7	-0.0	0.0	0.2	0.6	0.4	0.3
Illness, injury, bereavement, stress in last 2 years	0.1	0.2	0.6	0.5	-0.6	0.8	0.2	0.7	-0.1	0.6	0.0	0.2	0.5	0.3	0.6	0.4	0.1	0.1	0.4	0.2	0.6	0.4
Supplements: Vitamin C	0.1	0.1	1.5	-0.2	0.2	-1.2	0.5	-0.0	-0.5	-0.3	0.0	-0.1	-0.4	-0.1	-0.4	-0.0	-0.1	-0.1	0.0	0.1	-0.4	-0.0
Average weekly red wine intake	0.1	0.1	0.5	-0.3	0.5	-0.7	0.7	-0.4	0.2	-0.4	-0.2	-0.4	-0.4	-0.5	-0.4	-0.2	-0.1	-0.4	0.2	0.2	-0.4	-0.0
Friendships satisfaction	0.1	0.2	1.2	0.1	-0.3	1.1	0.9	0.5	-0.6	0.2	-0.0	0.0	0.3	0.0	0.0	0.6	-0.0	-0.3	0.3	0.5	0.1	0.3
Eye problems/disorders: Cataract	0.1	0.1	0.6	-0.2	0.3	-0.4	0.6	0.8	-0.6	-0.3	-0.0	-0.2	-0.2	0.1	-0.2	0.4	-0.1	-0.3	-0.2	0.6	-0.2	-0.0
Asthma (self-reported)	0.1	0.3	2.6	-0.3	-0.1	-0.3	0.4	-0.6	-1.6	-0.3	-0.7	-0.9	-0.2	-0.2	-0.1	0.2	-0.5	-0.6	0.1	0.5	-0.0	-0.1
Number of self-reported non-cancer illnesses	0.1	0.1	0.4	-0.3	0.1	-0.4	-0.2	0.6	-0.5	-0.3	0.3	0.3	-0.1	0.1	-0.3	-0.2	-0.2	0.5	0.5	-0.6	-0.2	0.2
Miserableness	0.1	0.2	1.3	-0.2	0.1	-0.5	-0.3	0.1	-0.3	-0.2	0.1	0.6	-0.2	-0.1	-0.3	-1.1	0.3	0.2	0.0	-0.8	-0.3	-0.3
Wears glasses or contact lenses	0.1	0.1	0.9	-0.4	0.3	-0.6	-0.0	0.6	-1.0	-0.4	-0.1	-0.3	-0.2	-0.2	-0.5	0.1	-0.3	-0.3	0.0	0.3	-0.4	-0.0
High cholesterol (Self-reported)	0.1	0.3	0.6	0.6	-0.6	0.6	0.3	0.4	-0.4	0.5	0.5	0.1	0.5	0.6	0.4	0.8	0.1	0.6	0.7	0.4	0.4	0.7
Medication: Lisinopril	0.1	0.1	0.4	0.2	-0.3	-0.3	-0.1	-0.2	-0.0	0.1	0.4	0.1	0.2	0.4	0.2	0.1	0.2	0.6	0.6	0.1	0.2	0.4
Ever smoked	0.1	0.2	0.7	0.4	-0.5	0.9	-0.4	0.3	0.7	0.4	0.5	0.5	0.4	0.4	0.4	0.5	0.4	0.5	-0.1	0.3	0.4	0.3
Fractured/broken bones in last 5 years	0.1	0.1	1.1	-0.1	-0.2	-0.3	0.0	1.1	0.5	-0.3	0.5	0.1	-0.1	0.3	-0.2	0.1	-0.2	0.5	-0.2	-0.2	-0.1	0.1
Diastolic blood pressure, automated reading	0.1	0.3	2.0	0.1	0.4	-0.8	-1.0	-0.3	-0.0	-0.0	0.3	0.6	-0.3	0.6	0.2	-0.1	-0.5	0.8	-0.3	-1.4	0.0	-0.4
Alcohol drinker status: Previous	0.1	0.1	0.5	0.1	-0.1	-0.1	0.7	-0.6	-0.6	0.2	-0.3	-0.4	0.1	-0.1	0.1	0.3	-0.5	0.2	0.2	-0.3	0.1	0.0
Breast Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Prostate Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Tanning	0.0	0.5	2.0	0.1	-0.3	0.1	-1.3	0.3	-0.1	0.1	0.9	1.4	0.1	0.5	0.0	-1.2	0.7	0.8	-0.4	-1.2	0.1	-0.4
Hand grip strength (left)	0.0	0.1	0.4	-0.1	0.0	0.3	0.0	0.1	-0.1	-0.1	-0.4	-0.5	-0.0	-0.2	-0.1	0.4	-0.1	-0.6	-0.4	0.6	-0.1	0.0
Multivitamins +/- minerals	0.0	0.0	0.2	0.2	0.1	0.2	0.0	-0.5	0.1	0.2	-0.1	0.0	-0.1	-0.1	0.2	-0.2	0.3	-0.3	-0.3	0.2	0.1	-0.3
Time employed in main current job	0.0	0.0	0.1	-0.1	0.3	0.0	-0.3	-0.0	0.0	-0.0	-0.3	-0.4	-0.2	-0.3	-0.1	-0.3	-0.2	-0.2	0.2	-0.1	-0.1	-0.1
Number of full brothers	0.0	0.0	0.1	-0.0	-0.1	0.1	0.1	0.3	0.4	-0.1	0.0	0.1	-0.1	0.4	0.2	-0.1	0.1	-0.1	0.1	-0.1	0.1	0.0
Smoking status: Previous	0.0	0.0	0.2	0.1	-0.4	-0.3	0.1	-0.1	0.3	0.2	0.1	-0.1	0.2	0.0	0.1	0.5	0.1	0.1	0.2	0.4	0.1	0.2
Medication: Paracetamol	0.0	0.1	0.6	-0.1	0.1	0.2	0.2	-0.8	-0.0	-0.1	0.0	-0.0	-0.1	-0.4	-0.3	-0.6	-0.0	0.2	0.1	-0.3	-0.2	-0.0

Hub : Genes

OAS1

Models

Trait associations