Hub : Genes

ODF3B

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Breast Mammary Tissue 0.1440 0.0580 2.3e-03 0.071 NA -0.003 NA 0.056 1.6e-04 NA 4.7e-01 NA 7.7e-04
2 GTEx Breast Mammary Tissue (Female) 0.1810 0.0706 7.0e-03 0.000 NA 0.002 NA -0.003 3.2e-01 NA 2.7e-01 NA 4.1e-01
3 METSIM Adipose 0.0933 0.0251 2.4e-07 0.068 0.054 0.060 0.054 0.064 2.0e-10 1.7e-08 2.1e-09 1.7e-08 6.4e-10
4 YFS Blood 0.0546 0.0133 1.1e-11 0.031 0.036 0.042 0.036 0.040 2.5e-10 5.1e-12 1.5e-13 6.7e-12 3.9e-13
5 TCGA Breast Invasive Carcinoma 0.0283 0.0112 8.2e-05 0.014 0.015 0.014 NA 0.019 5.1e-04 4.1e-04 4.9e-04 NA 5.7e-05
6 TCGA Glioblastoma Multiforme 0.1550 0.0780 5.2e-03 -0.007 0.067 0.059 NA 0.034 6.2e-01 4.6e-03 7.1e-03 NA 3.3e-02
7 TCGA Kidney Renal Clear Cell Carcinoma 0.0289 0.0158 9.9e-03 0.032 0.007 0.009 NA 0.014 1.4e-04 5.1e-02 3.1e-02 NA 9.0e-03
8 TCGA Lung Adenocarcinoma 0.0390 0.0206 6.7e-03 0.025 0.006 0.010 NA 0.009 5.6e-04 6.6e-02 2.2e-02 NA 2.5e-02
9 TCGA Testicular Germ Cell Tumors 0.1300 0.0630 5.6e-03 0.087 0.034 0.040 NA 0.048 5.3e-04 2.3e-02 1.6e-02 NA 8.4e-03

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bipolar Disorder (2018) 0.8 1.3 7.7 -0.5 -1.2 -1.1 -2.8 0.3 -0.3 0.1 0.8 0.3
Bipolar Disorder or Schizophrenia 0.9 2.2 5.6 -0.0 -2.4 0.4 -2.0 1.6 -0.6 1.1 1.5 1.8
Depressed Affect (Nagel 2018) 0.7 1.5 3.5 -0.4 1.3 0.8 1.4 1.6 1.9 1.2 1.3 -0.4
Depression (Nagel 2018) 0.9 1.4 4.1 -0.3 0.7 -1.7 -2.0 0.4 -1.3 -0.7 -1.1 -1.2
Intelligence (Savage-Jansen 2018) 0.7 2.0 9.1 0.2 -0.1 1.6 2.3 0.3 3.0 0.4 1.0 0.3
Neuroticism (Nagel 2018) 1.1 2.6 10.3 -0.3 2.2 -1.0 1.4 0.5 1.7 -0.7 -1.2 -3.2
Schizophrenia (2018) 0.8 1.7 3.9 0.4 -2.0 1.3 -0.4 1.7 -0.3 1.3 1.4 1.6
Schizophrenia vs Biploar Disorder 0.3 0.4 1.8 -0.3 -1.1 0.2 0.6 -1.3 0.0 0.0 0.0 0.0
Worry (Nagel 2018) 1.4 2.9 11.6 -1.3 1.0 -1.4 1.1 -0.2 1.0 -1.7 -2.2 -3.4
Alzheimer’s Disease (in mother) 1.0 1.2 3.7 -0.5 -1.9 -0.3 -1.3 1.1 -1.8 0.4 0.2 0.6
Alzheimer’s Disease (in father) 0.2 0.2 0.5 -0.3 -0.1 0.1 -0.2 0.6 0.2 0.7 0.6 0.6
Alzheimer’s Disease (including proxy) 0.7 1.0 2.8 -0.4 -1.0 0.3 -0.8 1.7 -1.3 1.1 0.8 0.9
Crohns Disease (2017) 0.5 1.0 2.0 0.1 0.6 -1.4 -1.3 -1.2 -1.2 -1.3 -0.8 0.2
Irritable Bowel Disease (IBD) 2.1 5.0 10.1 0.1 1.0 -3.0 -1.9 -2.7 -2.6 -3.2 -2.4 -1.0
Ulcerative Colitis (UC) 2.8 5.3 10.5 -0.4 0.6 -3.0 -1.8 -2.7 -2.9 -3.2 -2.6 -1.5
Major Depression (MDD) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
Reaction Time 1.8 3.4 8.9 -3.0 -2.8 -0.8 -2.4 1.2 -1.5 1.2 0.3 1.4
Verbal and Numeric Reasoning (VNR) 0.7 1.7 7.2 -0.8 0.2 1.1 2.4 -0.6 2.7 -0.1 0.3 -0.5
Breast Cancer 0.1 0.1 0.3 0.5 -0.3 -0.6 0.5 -0.5 -0.1 -0.3 -0.3 -0.1
Ovarian Cancer 2.8 3.7 7.1 -0.4 -0.7 -2.6 -1.9 -2.2 -1.7 -2.7 -2.3 -1.4
Prostate Cancer 1.1 1.6 3.7 -1.0 -0.8 -1.8 -1.9 -0.1 -1.6 -0.7 -0.8 -1.4
Age at First Birth 0.7 1.1 4.1 -0.1 1.1 0.7 0.3 2.0 -0.8 1.5 0.8 0.4
Bipolar Disorder (2011) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
Body Mass Index (BMI) (2010) 0.3 0.4 1.3 -0.3 1.1 -0.3 0.4 -0.7 0.7 -0.4 0.1 -0.8
Coronary Artery Disease (CAD) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
Crohns Disease (2012) 0.7 1.1 3.2 -0.0 0.3 -1.6 -1.8 -0.3 -1.0 -0.9 -1.3 0.0
Mean Putamen Volume 3.8 4.3 9.7 0.4 1.4 -2.1 0.9 -2.5 0.6 -3.1 -2.7 -2.9
Fasting Glucose 0.7 0.9 3.5 1.9 -0.8 -0.9 -0.8 -1.3 -0.4 -0.1 0.1 0.4
HbA1C 3.4 3.7 7.6 -0.3 0.1 -2.6 -0.3 -2.3 -0.9 -2.8 -2.5 -2.6
HDL Cholesterol 0.3 0.4 1.3 0.7 -0.6 0.8 -0.3 0.3 0.6 0.3 0.7 1.1
LDL Cholesterol 0.6 0.9 4.5 0.7 -2.1 0.8 1.3 0.4 0.6 0.1 0.6 -0.4
Lupus 0.3 0.4 1.4 0.9 -1.2 0.1 0.0 -0.0 1.0 0.3 0.5 0.0
Neuroticism (2016) 0.1 0.1 0.6 -0.1 0.1 0.1 0.7 0.1 -0.2 -0.5 -0.3 -0.5
Primary Biliary Cirrhosis 4.2 6.0 10.8 -2.3 -1.8 -3.3 -2.5 -2.4 -2.1 -2.6 -2.7 -1.9
Rheumatoid Arthritis 1.0 1.4 3.6 0.6 1.8 0.3 -0.7 0.6 -1.4 0.9 1.3 1.9
Schizophrenia (2014) 0.5 1.1 7.0 -0.1 -2.6 0.5 -1.0 0.7 -0.2 0.3 0.7 1.0
Triglycerides 0.6 1.0 2.8 0.4 -1.4 1.1 1.7 0.7 0.5 1.1 0.7 -0.1
Type 2 Diabetes (T2D) (2012) 0.5 0.6 4.6 -1.0 -2.1 0.1 -0.2 0.0 0.0 0.0 0.0 0.0
Ulcerative Colitis 2.9 4.3 7.6 -1.8 -0.4 -2.7 -2.5 -2.1 -2.5 -2.6 -1.8 -0.7
Blood Eosinophil Count 0.6 4.8 19.1 -1.2 0.2 -1.4 -4.4 0.4 -4.2 0.1 -0.3 1.6
Blood Platelet Count 0.2 1.9 3.3 1.7 -1.6 -1.8 -0.0 -0.3 -1.7 -0.9 -1.3 -1.7
Blood Red Count 25.0 241.3 542.9 1.7 -0.3 -23.3 -15.8 -14.7 -17.7 -17.1 -19.7 -12.9
Blood White Count 0.5 3.8 12.0 0.4 3.0 -1.3 -2.7 1.1 -3.5 0.2 -1.7 0.1
Heel T-Score 0.2 1.3 6.2 2.1 2.5 -0.5 -0.2 -0.1 0.6 -0.0 -0.3 0.1
BMI 0.5 3.1 11.2 -0.2 1.5 2.6 3.3 -0.3 1.9 0.6 1.6 1.1
Height 0.5 8.8 22.9 0.3 -0.3 4.0 0.7 3.1 0.6 3.1 4.4 4.8
Waist Hip Ratio (WHR) 0.5 2.4 6.2 1.0 2.3 -1.1 -0.6 -1.3 -2.5 -1.3 -2.0 -0.1
Systolic Blood Pressure 0.5 2.4 5.3 0.8 -0.1 1.8 0.1 1.6 0.9 2.1 2.3 2.0
Smoking Status 0.4 0.9 5.0 0.8 2.2 0.1 -0.5 0.8 0.8 0.8 0.2 -0.0
Allergy or Eczema 3.2 8.4 19.1 1.2 1.7 -4.4 -3.1 -2.3 -3.3 -2.9 -3.6 -2.5
Cardiovascular Disease 1.1 3.6 6.7 -1.0 -2.6 2.3 0.9 2.4 0.9 2.3 1.9 1.6
Hypothyroidism (self reported) 0.8 1.8 14.5 0.9 -3.8 -0.1 -0.3 -0.3 0.7 -0.4 -0.6 -0.3
Respiratory disease 2.1 4.7 9.4 1.6 1.6 -2.6 -0.6 -2.5 -2.9 -3.1 -2.0 -1.4
Type 2 Diabetes (T2D) (2018) 0.8 1.5 3.2 -0.7 -0.9 0.6 -1.0 1.7 -0.9 1.4 1.8 1.5
Lung FEV1/FVC ratio 0.2 0.8 5.1 0.3 -0.3 0.3 1.0 -0.7 2.2 -0.0 0.4 -0.5
Lung FVC 0.8 4.1 9.2 -0.5 -3.0 2.3 1.5 1.8 2.3 2.2 1.7 1.8
Neuroticism 0.9 2.1 9.7 -0.1 1.8 -1.6 0.6 0.8 0.8 -0.2 -1.3 -3.1
Chronotype (morning person) 0.9 2.2 4.2 -1.2 2.1 -1.5 -1.5 -0.5 -1.7 -1.1 -2.0 -1.0
Hair Pigment 0.0 0.6 2.1 0.1 0.7 -0.2 0.9 -1.4 1.2 -0.7 0.3 -0.2
Tanning 0.1 1.2 4.5 1.9 -0.4 0.5 1.3 -0.2 2.1 -0.1 -0.8 -0.3
Hand grip strength (left) 0.1 0.3 1.3 0.4 -0.4 -0.4 -0.5 -1.1 -0.7 -0.6 0.0 0.2
Number of treatments/medications taken 0.5 1.0 3.6 0.5 0.1 1.0 0.1 1.9 -0.7 1.2 0.9 1.2
Average weekly spirits intake 0.4 0.5 1.7 -1.3 0.2 0.7 0.7 0.0 0.9 0.1 -0.7 0.5
Sensitivity / hurt feelings 0.5 0.8 4.7 0.3 2.2 -0.5 0.1 0.6 -0.1 0.4 -0.5 -1.3
Frequency of depressed mood in last 2 weeks 1.2 1.7 4.3 0.4 0.5 -1.8 -1.4 0.0 0.1 -1.1 -2.1 -2.0
Hearing difficulty/problems: Yes 3.3 5.1 14.1 2.3 -0.2 -2.2 0.4 -2.7 -0.8 -2.7 -3.8 -2.4
Relative age of first facial hair 0.2 0.4 1.3 0.2 1.1 0.7 1.0 0.7 0.6 0.2 0.2 -0.2
Other serious medical condition/disability diagnosed by doctor 0.5 0.7 2.9 1.1 1.7 0.2 0.6 -0.3 -0.4 -0.8 -0.9 -0.2
Ever used hormone-replacement therapy (HRT) 0.3 0.4 1.6 -0.4 -0.1 0.0 0.7 0.4 -0.2 -0.5 -0.9 -1.3
Ever had hysterectomy (womb removed) 0.9 1.0 2.7 -0.4 -0.0 -0.5 1.0 -0.9 -0.6 -1.6 -1.6 -0.9
Systolic blood pressure, automated reading 0.7 2.1 3.8 -0.9 1.1 1.9 1.6 1.6 1.9 1.7 1.1 0.7
Eye problems/disorders: Diabetes related eye disease 0.7 0.8 5.8 -0.6 -2.4 0.2 -0.4 0.0 -0.2 0.0 0.9 0.4
Angina 1.5 2.0 6.2 -1.0 -1.8 0.4 -1.2 2.5 -0.4 2.3 0.4 0.5
Medication for hormone replacement therapy 2.8 3.1 9.1 1.6 1.0 -1.6 0.8 -1.6 -0.4 -2.1 -2.2 -3.0
Vitamin and mineral supplements 0.4 0.5 1.3 -1.0 0.8 -0.8 -0.0 -0.3 0.3 -0.5 -1.0 -1.1
Supplements: Zinc 1.2 1.3 3.3 1.8 -0.8 -0.8 0.1 -1.5 0.4 -0.9 -1.2 -1.4
Medication: Co-codamol 1.7 1.9 4.7 1.1 1.8 -0.2 2.2 -1.5 0.1 -1.1 -1.4 -1.7
Medication: Metformin 2.1 2.9 5.3 -1.1 -1.8 0.9 -2.0 1.9 -0.1 1.9 2.1 2.3
Diabetes (father) 1.5 1.9 4.0 -0.8 -1.5 -1.4 -1.2 -1.8 -1.2 -2.0 -1.0 -1.0
Diabetes (mother) 1.1 1.4 6.1 -1.5 -2.5 0.5 1.3 -0.2 1.4 -0.2 0.4 0.0
Severe depression (siblings) 1.2 1.3 4.7 -1.1 -0.8 0.3 -0.3 2.2 -0.1 2.0 1.1 0.3
Pack years adult smoking proportion 2.3 3.5 8.5 2.9 1.5 -0.5 1.4 -1.9 0.5 -2.1 -2.5 -2.1
Impedance of leg (right) 0.5 2.4 11.0 0.7 -2.2 -1.3 -3.3 1.3 -1.1 0.8 -0.4 0.4
Leg fat-free mass (left) 0.9 4.7 11.0 -0.0 1.9 3.3 3.2 0.5 1.4 1.3 3.0 2.1
Trunk fat percentage 0.9 3.6 7.3 0.1 2.3 2.4 1.2 1.7 0.3 2.5 2.7 1.7
Hand grip strength (right) 0.1 0.2 0.8 -0.5 -0.9 -0.0 -0.2 0.3 -0.3 0.3 0.4 0.3
Townsend deprivation index at recruitment 1.0 1.5 6.5 0.9 2.5 -0.5 -1.0 0.3 -1.9 0.4 0.4 0.7
Current tobacco smoking 0.4 0.6 3.7 0.3 1.9 0.6 -0.2 -0.0 -0.9 -0.1 -0.1 0.9
Average weekly fortified wine intake 1.6 1.9 8.7 0.1 -0.8 1.4 2.3 0.4 3.0 0.2 0.6 0.2
Maternal smoking around birth 1.0 1.5 3.8 1.9 -0.5 -1.6 -0.7 -1.8 -0.3 -1.1 -1.0 -0.6
Fed-up feelings 0.1 0.1 0.3 -0.3 -0.4 -0.2 -0.5 0.1 0.1 -0.4 -0.2 0.2
Frequency of unenthusiasm / disinterest in last 2 weeks 0.8 1.1 4.2 -1.2 -0.3 -1.3 -2.1 0.7 -1.1 -0.4 -0.2 -0.3
Relative age voice broke 0.3 0.4 1.4 -0.2 -1.0 -0.2 -0.2 0.1 0.5 -0.4 -1.2 -1.0
Taking other prescription medications 0.6 1.0 4.9 0.2 -0.9 -0.5 -1.2 0.1 -2.2 -0.5 -0.8 0.6
Age when periods started (menarche) 0.9 2.2 6.0 0.3 -1.3 -1.9 -0.9 -1.1 -1.3 -1.5 -2.4 -1.5
Bilateral oophorectomy (both ovaries removed) 3.4 3.9 9.2 -0.3 -2.4 -0.9 2.0 -1.6 1.3 -2.0 -2.7 -3.0
Heel bone mineral density (BMD) T-score, automated (left) 0.6 1.3 4.0 1.8 2.0 0.8 0.5 -0.3 0.0 0.1 1.3 1.3
Tinnitus: Yes, but not now, but have in the past 1.0 1.1 3.1 0.6 0.4 1.7 1.8 -0.2 1.4 0.2 0.3 1.0
Qualifications: CSEs or equivalent 0.6 0.7 2.9 0.8 -0.3 -1.3 -0.6 -0.2 -0.2 -0.4 -0.8 -1.7
Serious illness, injury or assault to yourself 0.2 0.2 0.6 -0.1 -0.4 -0.4 0.5 0.5 -0.0 -0.5 -0.8 -0.6
High blood pressure 0.6 1.7 3.2 0.1 -1.3 1.7 0.6 1.8 0.8 1.5 1.3 1.6
Hayfever, allergic rhinitis or eczema 1.5 3.2 7.8 1.1 0.8 -2.8 -2.3 -1.3 -2.2 -1.5 -1.9 -1.0
Multivitamins +/- minerals 0.7 0.8 2.2 1.1 -0.4 1.3 0.8 0.6 0.2 0.7 0.9 1.5
Stomach or abdominal pain in last month 0.1 0.1 0.3 0.5 -0.5 0.2 -0.2 0.3 -0.1 0.4 -0.2 0.4
Supplements: Glucosamine 0.9 1.2 7.2 2.7 0.3 0.5 0.1 0.4 0.7 1.0 1.1 0.3
Diverticular disease/diverticulitis (self-reported) 1.3 1.6 3.6 -0.1 1.3 -1.3 0.3 -1.9 -1.3 -1.4 -1.3 -1.2
Medication: Atenolol 0.9 1.2 7.6 -0.4 -2.7 1.0 -0.5 0.7 0.2 0.3 -0.1 0.8
Medication: Levothyroxine sodium 0.7 1.2 5.1 0.0 -2.3 1.4 0.6 1.4 0.2 0.7 -0.3 0.7
Sitting height 0.5 3.5 8.2 1.5 0.8 2.9 1.8 1.0 1.9 1.4 2.1 2.4
Chronic bronchitis/emphysema (father) 2.1 2.5 5.0 -0.8 0.6 2.2 2.2 0.7 2.0 1.0 1.9 1.7
High blood pressure (mother) 0.4 0.5 1.4 -1.0 0.5 1.2 0.3 0.8 -0.3 0.8 0.4 0.6
Body mass index (BMI) 0.8 3.4 7.7 -1.0 1.2 2.8 2.8 0.8 1.3 1.6 2.3 1.4
Impedance of leg (left) 0.4 2.1 9.2 0.4 -2.2 -1.2 -3.0 1.2 -0.9 0.9 -0.3 0.3
Leg predicted mass (left) 0.9 4.9 11.5 -0.0 1.8 3.4 3.2 0.5 1.4 1.4 3.1 2.2
Trunk fat mass 1.1 4.8 10.2 -0.1 1.9 3.2 2.0 1.7 0.8 2.5 3.2 2.3
Waist circumference 0.4 1.6 5.3 -0.3 1.3 1.9 2.3 -0.1 0.4 0.7 1.1 1.3
Number of incorrect matches in round 0.7 1.1 2.7 0.0 1.4 0.9 0.8 1.6 0.5 1.6 0.2 -1.1
Past tobacco smoking 1.0 1.9 5.4 -0.4 -1.0 -0.7 -0.3 -2.2 -1.4 -2.3 -1.7 0.5
Alcohol usually taken with meals 0.8 1.2 3.3 1.4 0.7 -0.7 0.6 -1.4 0.1 -1.0 -1.3 -1.8
Nervous feelings 0.8 1.5 4.3 -0.5 1.8 -1.1 0.3 -0.7 -0.1 -1.6 -1.3 -2.1
Frequency of tenseness / restlessness in last 2 weeks 0.9 1.3 3.3 1.1 -0.3 -1.8 -1.1 -0.4 -1.1 -1.2 -1.4 -1.2
Hearing difficulty/problems with background noise 0.6 0.9 3.5 0.4 -1.9 -0.8 0.1 -1.1 0.3 -0.6 -1.5 -0.6
Hair/balding pattern: Pattern 2 0.3 0.4 1.4 -0.0 -0.2 -0.6 -1.2 -0.7 0.2 -1.0 -0.3 0.5
Had menopause 0.7 0.9 1.7 -1.0 0.8 1.2 -0.2 1.3 -0.7 1.2 0.4 1.2
Had other major operations 1.6 2.0 4.0 0.7 1.1 -1.7 -0.6 -2.0 -1.4 -2.0 -1.3 -1.2
Forced vital capacity (FVC) 1.9 7.3 14.8 1.0 -2.6 3.8 3.2 1.2 2.9 2.1 3.1 3.0
Heel bone mineral density (BMD) T-score, automated (right) 0.4 0.9 2.8 1.7 0.9 1.0 0.1 0.5 -0.1 0.8 0.9 1.3
Ever unenthusiastic/disinterested for a whole week 0.9 1.1 3.1 1.7 0.7 -0.9 -1.8 0.6 -1.2 -0.8 -0.2 0.3
Qualifications: None of the above 0.9 1.9 7.6 -1.8 0.5 -0.2 -1.8 0.8 -2.8 0.0 -0.1 1.6
Financial difficulties in last 2 years 0.3 0.4 1.8 0.2 -0.1 0.2 0.3 -1.3 -0.3 -1.2 -0.5 0.2
Mouth/teeth dental problems 0.5 0.8 2.7 -1.0 -1.3 0.0 1.0 0.3 1.7 0.1 -0.2 -0.9
Heart attack 0.6 0.7 2.4 -0.5 -0.1 0.4 -0.6 1.5 -0.3 1.5 0.9 0.6
Allergy 1.0 2.3 5.0 -0.5 -0.6 2.2 1.0 1.5 2.1 1.8 1.8 1.0
Pain all over the body in last month 0.6 0.7 1.7 -0.8 -0.4 -1.3 -0.6 0.2 -1.0 -0.4 -0.7 -1.2
Diabetes (self-reported) 0.2 0.3 1.0 -0.1 -1.0 0.0 -0.5 0.3 -0.7 0.6 0.4 0.5
Hayfever/allergic rhinitis (self-reported) 2.4 3.2 7.0 0.1 -0.0 -2.7 -1.9 -2.1 -1.3 -2.3 -2.1 -1.5
Medication: Ramipril 0.7 0.9 3.2 0.0 0.7 -0.0 -1.0 1.8 0.1 1.7 0.7 0.1
Medication: Simvastatin 1.1 1.6 4.0 -0.5 -0.2 2.0 0.9 1.2 -0.5 1.2 1.9 1.6
Fluid intelligence score 1.3 2.7 12.0 -0.8 -0.8 1.5 2.9 -0.8 3.5 -0.2 0.1 0.1
Illnesses of siblings 0.3 0.5 1.3 0.5 0.6 0.9 1.0 -0.4 1.1 0.4 0.1 0.4
Neuroticism score 0.6 1.3 5.7 -0.7 0.9 -1.2 0.8 0.7 0.6 -0.4 -1.2 -2.4
Weight 1.2 6.1 15.3 -0.7 1.0 3.9 3.0 1.4 1.5 2.3 3.5 2.7
Impedance of arm (right) 0.4 2.0 8.0 0.9 1.1 -1.6 -2.8 1.3 -1.2 1.0 -0.6 -0.8
Arm fat percentage (right) 0.6 2.3 4.2 -0.4 1.9 2.0 1.7 1.3 0.6 1.9 1.8 1.0
Trunk fat-free mass 0.9 4.9 13.5 -0.7 -0.2 3.7 3.2 0.8 1.6 1.4 2.7 2.7
Hip circumference 1.0 4.4 10.4 -0.9 0.3 3.2 3.0 0.9 2.2 1.7 2.6 2.0
Time employed in main current job 0.8 0.9 3.0 -0.1 -0.7 -0.2 -1.6 1.7 -1.2 0.9 0.3 0.3
Alcohol intake versus 10 years previously 0.7 1.0 6.4 -0.0 -2.5 0.6 0.9 -0.4 0.1 -0.8 0.5 0.4
Father’s age at death 1.6 2.2 4.6 1.0 0.5 -2.0 -0.8 -2.1 -1.8 -1.4 -1.8 -0.9
Worrier / anxious feelings 1.1 2.0 8.0 -0.9 1.6 -1.4 0.3 1.0 0.8 -0.4 -1.8 -2.8
Frequency of tiredness / lethargy in last 2 weeks 0.7 1.1 2.7 0.1 -0.9 -1.6 -0.7 -1.1 -0.3 -1.4 -1.2 -1.2
Falls in the last year 1.1 1.4 3.6 0.0 1.9 -1.4 0.2 -0.6 0.0 -0.1 -1.8 -1.9
Hair/balding pattern: Pattern 3 0.6 0.9 2.8 1.3 1.7 0.9 1.6 -0.3 0.2 -0.1 -0.5 0.2
Number of live births 0.6 0.8 2.5 -1.4 0.5 1.0 0.3 -0.4 -0.9 0.1 0.8 1.6
Forced expiratory volume in 1-second (FEV1) 1.8 6.0 12.6 0.9 -2.4 3.1 3.4 0.1 3.5 1.4 2.7 2.1
Pulse rate 0.1 0.1 0.5 0.2 -0.3 -0.3 0.4 -0.2 -0.7 0.4 -0.4 -0.0
Happiness 1.1 1.4 5.3 0.0 1.3 -1.2 -0.8 -1.0 -2.3 -1.5 -0.1 0.1
Noisy workplace 0.1 0.2 0.5 0.7 -0.3 0.5 -0.1 -0.1 0.2 -0.4 -0.1 0.5
Qualifications: A levels/AS levels or equivalent 0.7 1.6 2.9 0.4 0.7 -1.7 -0.0 -1.6 -0.2 -1.6 -1.6 -1.7
Serious illness, injury or assault of a close relative in last 2 years 0.4 0.5 1.6 -1.3 -0.0 0.3 0.1 -0.7 0.7 -0.4 0.8 1.1
Mouth/teeth dental problems: Dentures 0.4 0.7 2.8 0.5 0.4 0.4 -0.8 1.3 -1.7 0.8 0.2 0.3
Asthma 0.9 1.7 4.2 0.2 0.7 -1.8 -0.7 -1.5 -2.0 -1.5 -1.3 -0.7
Medication: Ibuprofen (e.g. Nurofen) 0.3 0.4 1.0 0.3 0.3 -0.6 0.3 -0.7 -0.8 -1.0 -1.0 -0.3
Medication: Cholesterol lowering 1.1 1.7 4.7 -0.2 -1.0 1.6 0.2 2.2 -0.1 1.7 1.3 1.4
Depression (self-reported) 1.1 1.3 4.4 -1.2 -0.1 -1.3 -2.1 0.5 -1.7 -0.3 0.4 0.7
Medication: Lansoprazole 0.5 0.6 2.7 1.7 0.9 -0.1 -0.5 -0.1 -1.1 0.2 -0.3 0.1
Prospective memory result 0.8 0.9 6.9 0.6 2.6 0.5 0.3 0.9 -0.2 0.3 -0.1 -0.1
Lung cancer (father) 1.5 1.8 3.3 0.2 -1.1 -1.1 0.3 -1.7 1.8 -1.3 -1.6 -1.7
Illnesses of mother 1.0 1.2 2.3 1.2 1.5 -1.5 -0.1 -1.0 -0.3 -0.7 -1.1 -1.5
Forced expiratory volume in 1-second (FEV1), Best measure 1.5 4.9 10.1 1.2 -1.7 2.9 3.2 0.0 3.1 1.3 2.5 2.0
Pulse wave Arterial Stiffness index 0.5 0.6 1.8 -1.0 -1.3 0.7 0.2 0.8 -0.0 0.9 0.5 0.3
Impedance of arm (left) 0.3 1.6 5.5 1.7 1.1 -1.5 -2.3 0.5 -0.8 0.6 -0.7 -0.8
Arm fat mass (right) 0.9 3.6 8.5 -0.8 1.1 2.9 2.1 1.4 0.8 2.1 2.6 1.8
Trunk predicted mass 0.8 4.7 13.0 -0.7 -0.3 3.6 3.2 0.7 1.6 1.3 2.6 2.7
Standing height 0.4 3.6 9.1 0.8 -0.1 2.8 1.0 1.5 0.6 1.9 2.7 3.0
Length of working week for main job 0.7 0.7 1.7 0.8 0.6 -0.4 0.7 -1.3 0.5 -1.0 -1.2 -0.7
Exposure to tobacco smoke at home 0.6 0.6 3.4 -0.6 1.8 0.1 0.6 -0.7 -0.7 -0.4 0.6 0.1
Breastfed as a baby 0.6 0.7 3.6 0.2 0.0 1.4 1.9 -0.3 0.8 0.4 0.0 -0.1
Tense / ‘highly strung’ 2.5 4.1 11.4 0.9 1.3 -2.7 0.1 -1.5 0.1 -2.2 -3.0 -3.4
Seen doctor (GP) for nerves, anxiety, tension or depression 1.5 2.3 4.7 0.1 0.9 -1.8 -0.2 -1.9 -0.8 -2.0 -2.2 -2.0
Hair/balding pattern: Pattern 4 0.3 0.7 1.6 1.3 -0.9 -0.2 -0.8 0.6 -0.0 1.3 1.1 0.4
Birth weight of first child 1.7 3.0 6.7 1.3 1.7 -1.8 1.0 -2.6 -0.1 -1.9 -2.0 -2.0
Peak expiratory flow (PEF) 1.4 3.1 13.0 1.5 -1.4 1.6 2.5 0.4 3.6 1.2 0.9 0.3
Pulse wave reflection index 0.3 0.3 1.2 -0.5 -1.1 -0.4 -0.9 0.6 -0.3 0.2 -0.1 -0.2
Ever highly irritable/argumentative for 2 days 1.0 1.2 7.0 2.6 -0.2 0.0 0.2 -0.9 -0.1 -1.2 0.1 1.1
Loud music exposure frequency 0.6 0.7 2.1 0.7 -0.4 0.7 0.1 0.9 -0.4 0.9 1.5 1.1
Qualifications: O levels/GCSEs or equivalent 0.2 0.3 0.8 0.0 -0.9 -0.3 0.3 -0.9 0.2 -0.5 -0.4 -0.5
Mouth/teeth dental problems: Bleeding gums 0.9 1.2 3.1 1.8 1.2 -0.7 -1.0 -1.5 -1.0 -1.0 -0.4 0.8
Blood clot in the leg (DVT) 0.7 0.9 2.2 1.0 -0.3 0.2 1.5 -1.1 -0.9 -1.5 -0.8 -0.4
Medication: Paracetamol 0.3 0.5 1.2 -1.1 1.1 0.4 0.7 0.5 0.3 0.3 0.7 0.4
Headache pain in last month 0.7 1.2 2.8 1.2 -0.5 0.2 1.1 0.9 1.7 1.3 -0.7 -1.4
Medication for cholesterol, blood pressure or diabetes 0.4 0.7 1.6 -0.3 0.2 -1.2 -1.0 -1.3 -0.0 -1.1 -0.5 -0.7
Glaucoma (self-reported) 1.0 1.2 3.4 0.5 1.2 -1.2 0.7 -0.6 0.8 -0.7 -1.4 -1.8
Gout (self-reported) 0.7 1.0 3.9 0.4 -0.5 -0.8 0.3 -0.9 0.1 -0.9 -2.0 -1.4
Hypothyroidism/myxoedema (self-reported) 0.7 1.4 10.4 0.8 -3.2 0.6 -0.2 0.6 -0.1 0.2 -0.2 0.6
Medication: Amlodipine 0.9 1.2 4.3 0.2 -0.6 1.1 -0.5 0.9 -0.6 1.2 1.5 2.1
Medication: Ventolin 100micrograms inhaler 0.6 0.8 2.3 0.2 -0.8 -0.7 -0.6 -1.5 -1.2 -1.4 -0.4 0.1
Birth weight 0.9 1.9 6.0 0.6 0.5 -0.4 1.9 -2.4 0.1 -1.6 -1.0 -1.7
Chronic bronchitis/emphysema (mother) 0.2 0.3 1.3 1.1 -0.6 0.1 -0.2 0.5 0.2 0.2 0.5 0.4
High blood pressure (siblings) 0.3 0.5 1.4 -0.4 -1.2 -1.0 -0.9 0.1 -0.7 -0.4 -0.3 -0.5
Forced vital capacity (FVC), Best measure 1.2 4.4 8.9 1.2 -1.7 3.0 2.7 0.6 2.3 1.5 2.5 2.4
Body fat percentage 0.9 3.5 7.2 -0.2 1.8 2.6 1.5 1.6 0.6 2.4 2.7 1.7
Leg fat percentage (right) 0.7 2.5 6.3 -0.4 0.3 2.5 1.4 1.1 1.0 1.8 2.3 1.8
Arm fat-free mass (right) 0.8 4.2 11.8 -0.2 0.2 3.4 2.7 0.4 1.0 1.1 2.9 2.9
Exposure to tobacco smoke outside home 1.4 1.9 7.6 -0.2 2.1 0.6 0.4 1.0 0.3 1.8 2.8 0.7
Comparative body size at age 10 0.5 1.5 4.6 -0.6 1.2 -0.7 0.7 -2.1 0.7 -2.0 -0.6 -1.2
Number of full brothers 0.5 0.7 2.4 -0.4 -1.5 0.5 -0.1 0.9 0.9 1.1 0.3 0.6
Worry too long after embarrassment 1.5 2.5 12.2 -0.4 0.0 -2.0 -0.3 0.7 0.8 -0.1 -2.1 -3.5
Seen a psychiatrist for nerves, anxiety, tension or depression 3.4 4.4 8.1 2.4 0.3 -2.7 -0.4 -2.5 -0.3 -2.5 -2.5 -2.8
Wheeze or whistling in the chest in last year 1.0 1.7 3.0 -0.2 1.7 -1.6 -0.9 -0.5 -1.5 -1.3 -1.7 -1.4
Number of children fathered 2.1 2.4 6.5 -0.2 -0.2 2.1 2.2 1.7 2.5 1.5 1.0 -0.5
Reason for reducing amount of alcohol drunk: Health precaution 1.4 1.7 5.1 -1.0 0.0 1.7 0.9 0.2 0.5 0.8 2.1 2.2
Age at first live birth 0.3 0.5 0.8 -0.3 -0.9 -0.6 -0.1 -0.6 0.9 -0.9 -0.7 -0.7
Pulse wave peak to peak time 0.3 0.4 1.9 0.9 1.4 -0.3 0.1 -0.6 0.2 -0.6 -0.1 0.0
Health satisfaction 1.0 1.3 3.6 -0.1 -1.5 -1.2 -1.1 -1.3 -1.3 -1.9 -0.4 -0.1
Shortness of breath walking on level ground 1.1 1.2 4.0 0.1 -1.2 0.6 2.0 -1.0 2.0 -0.8 -0.2 -0.2
Qualifications: College or University degree 0.5 1.7 3.2 1.4 -0.0 -1.2 0.3 -1.7 1.1 -1.7 -1.0 -1.8
Eye problems/disorders: None of the above 2.2 2.5 5.2 0.5 0.7 2.3 1.2 1.1 2.1 1.6 1.8 2.0
Mouth/teeth dental problems: Loose teeth 0.5 0.6 1.6 -0.7 -0.1 0.6 -0.9 1.0 -0.3 0.6 0.7 1.3
Emphysema/chronic bronchitis 0.7 0.8 4.6 2.2 1.3 -0.1 0.3 -0.5 0.3 -0.4 0.7 -0.2
Medication for pain relief, constipation, heartburn 0.3 0.5 1.3 0.2 -0.8 -0.3 0.5 -1.2 0.8 -0.9 -0.6 -0.9
Neck or shoulder pain in last month 0.3 0.5 1.5 0.5 0.3 0.1 -0.6 -0.5 -1.2 0.1 -0.7 1.1
Medication: Blood pressure 0.7 1.3 3.5 1.2 0.2 1.5 0.6 1.9 0.5 1.4 0.9 1.2
Angina (self-reported) 1.6 2.1 6.2 -0.8 -2.1 0.5 -1.2 2.5 -0.5 2.2 0.4 0.5
Migraine (self-reported) 0.5 0.6 2.8 -0.4 -0.3 -1.2 -0.0 0.2 0.1 0.1 -0.8 -1.7
Medication: Ibuprofen 0.4 0.5 1.1 -0.6 -0.1 -0.7 0.1 -0.7 -1.0 -1.0 -0.8 -0.4
Medication: Allopurinol 0.7 0.9 2.9 0.5 0.1 -0.8 0.5 -1.2 -0.3 -1.0 -1.7 -1.3
Medication: Omeprazole 0.6 0.8 3.6 0.0 -1.9 0.6 0.0 1.1 0.4 0.7 0.5 0.9
Medication: Seretide 50 evohaler 0.2 0.2 0.6 0.6 0.4 0.4 0.8 -0.4 0.1 0.0 0.5 0.2
Mean time to correctly identify matches 1.7 3.2 8.9 -2.7 -3.0 -0.7 -2.4 1.6 -1.1 1.2 -0.3 0.9
Heart disease (mother) 1.0 1.2 3.4 -0.7 -1.1 1.8 1.0 0.5 1.4 0.8 0.5 1.2
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.2 0.2 0.9 -0.2 -0.3 -0.2 -0.4 -0.9 -0.1 -0.7 -0.2 -0.3
Whole body fat mass 1.1 4.6 10.5 -0.2 1.4 3.2 2.2 1.5 1.0 2.4 3.1 2.3
Leg fat mass (right) 1.1 4.3 11.4 -0.5 0.5 3.4 2.4 1.2 1.4 2.1 2.9 2.2
Arm predicted mass (right) 0.7 3.6 10.2 -0.3 0.2 3.2 2.6 0.2 0.9 0.7 2.7 2.7
Pulse rate, automated reading 0.1 0.2 0.6 0.2 0.8 -0.0 0.4 -0.3 -0.2 0.3 -0.6 0.2
Alcohol intake frequency. 0.4 1.0 3.1 -0.4 0.9 0.6 -0.8 1.2 -1.8 0.8 0.8 1.0
Comparative height size at age 10 0.7 3.7 12.1 -1.6 0.0 2.3 0.1 2.0 0.2 2.0 2.4 3.5
Number of full sisters 1.5 1.8 4.3 -1.5 -1.3 1.5 -0.2 1.5 -0.9 1.3 1.2 2.1
Suffer from ‘nerves’ 2.1 3.4 8.9 -1.4 -0.7 -2.5 -0.4 -0.6 -0.7 -2.0 -2.8 -3.0
Overall health rating 0.7 1.5 5.8 0.1 -0.0 -0.6 0.2 -1.5 -1.5 -2.4 -1.6 -0.7
Chest pain or discomfort 0.3 0.4 1.1 0.5 -0.3 -0.9 -1.0 -0.0 0.3 -0.7 -0.8 -0.7
Had major operations 2.2 2.6 5.0 2.0 2.2 -1.1 0.3 -1.7 -1.6 -1.6 -1.8 -1.5
Age at last live birth 0.2 0.3 1.0 0.3 -0.3 -0.7 0.0 -0.1 1.0 -0.5 -0.5 -0.8
Family relationship satisfaction 0.1 0.1 0.6 0.3 -0.4 -0.2 -0.0 -0.5 -0.2 -0.8 -0.3 0.0
Leg pain on walking 0.5 0.6 2.3 0.4 -0.8 0.1 -0.7 -0.8 -0.5 -0.2 0.7 1.5
Qualifications: NVQ or HND or HNC or equivalent 0.9 1.1 4.9 1.1 0.0 0.5 0.9 -1.1 2.2 -0.3 0.8 0.5
Commuting to job workplace: Car/motor vehicle 2.9 3.3 7.7 -0.0 -1.0 2.8 2.3 0.9 2.3 1.9 1.9 1.4
Illness, injury, bereavement, stress in last 2 years 0.3 0.4 1.5 0.6 1.2 0.4 -0.0 0.3 -0.4 0.9 0.3 -0.1
Medication: Aspirin 1.3 1.7 3.6 0.8 -1.3 0.8 -1.3 1.9 -0.6 1.7 1.0 1.5
Supplements: Vitamin C 1.6 1.9 5.7 1.0 -2.4 -1.7 -1.3 -1.0 -1.1 -0.7 -0.8 -1.4
Knee pain experienced in last month 0.5 0.8 1.6 -0.4 1.1 1.3 0.9 0.5 0.0 1.0 1.2 1.0
Hypertension (Self-reported) 0.8 2.1 4.3 -0.4 -1.6 2.0 0.8 2.1 0.9 1.6 1.2 1.7
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.5 0.5 2.3 0.7 -0.7 -0.6 0.4 0.7 0.4 0.4 -0.3 -1.5
Illnesses of father: Heart disease 3.0 4.2 8.6 -0.3 -1.3 2.6 0.7 2.9 0.7 2.0 2.8 2.9
Illnesses of siblings: Diabetes 2.8 3.5 7.2 0.9 0.7 -2.7 -2.2 -1.9 -2.1 -2.4 -1.5 -1.3
Smoking status: Previous 0.6 0.9 2.9 0.7 0.8 0.1 -0.2 1.4 1.0 1.7 1.1 -0.5
Forced expiratory volume in 1-second (FEV1), predicted 0.1 0.3 0.8 0.9 0.5 0.7 0.4 -0.3 0.2 -0.0 0.2 0.8
Whole body fat-free mass 0.9 5.0 13.4 -0.3 0.7 3.7 3.3 0.6 1.5 1.4 2.9 2.6
Leg fat-free mass (right) 0.8 4.4 11.2 0.0 1.9 3.1 3.4 0.1 1.5 1.0 2.9 1.9
Arm fat percentage (left) 0.6 2.3 4.3 -0.2 2.0 2.1 1.8 1.1 0.7 1.8 1.9 0.9
Average weekly red wine intake 2.6 3.8 12.0 -0.2 0.6 0.0 2.5 -0.9 3.1 -1.3 -1.7 -3.5
Handedness (chirality/laterality): Left-handed 0.8 1.0 2.9 0.3 1.7 0.9 1.6 -0.5 1.3 -0.5 0.6 0.0
Mood swings 0.3 0.6 1.5 -1.0 0.7 0.4 0.6 1.2 0.7 0.4 1.0 -0.3
Loneliness, isolation 0.5 0.6 1.6 -0.2 1.3 -1.0 -0.7 1.1 -0.4 0.5 -0.6 -0.7
Long-standing illness, disability or infirmity 1.5 2.3 9.7 0.1 1.4 -1.4 -2.0 -0.5 -3.1 -1.0 -1.2 0.2
Ever had bowel cancer screening 0.1 0.2 1.0 -0.1 -1.0 -0.2 -0.1 0.4 0.4 0.4 0.1 -0.2
Diabetes diagnosed by doctor 0.6 0.9 2.9 -0.3 -1.3 -0.6 -1.5 0.5 -1.7 0.5 0.5 0.6
Ever had stillbirth, spontaneous miscarriage or termination 0.8 0.9 4.7 0.2 0.4 -0.4 0.5 -1.3 0.2 -2.2 -0.9 -0.2
Friendships satisfaction 0.7 0.8 2.5 -0.2 -1.1 0.1 1.0 -1.1 -0.3 -1.6 -1.1 -0.2
Qualifications: nursing, teaching 0.5 0.7 3.2 -0.1 -1.2 0.4 0.7 0.5 1.8 0.7 -0.4 -0.5
Commuting to job workplace: Walk 2.8 3.0 6.3 1.9 1.3 -2.5 -1.3 -1.5 -1.2 -1.3 -1.9 -2.2
Eye problems/disorders: Cataract 0.4 0.5 0.9 0.3 -0.4 -0.8 -0.1 -0.6 -0.9 -0.8 -0.9 -0.8
Mouth/teeth dental problems: Mouth ulcers 0.5 0.7 2.5 1.0 0.7 -0.4 0.4 -0.8 0.5 -0.9 -1.6 -0.8
Medication for cholesterol 0.3 0.5 1.0 -0.7 0.3 0.2 -0.8 0.6 0.1 0.9 1.0 0.9
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.6 0.7 2.6 -0.2 1.6 -0.3 -0.7 0.9 0.7 1.1 0.1 -0.7
Back pain experienced in last month 0.9 1.3 2.7 0.7 0.3 0.2 1.6 -1.5 0.8 -1.4 -1.3 -1.4
Mineral and other dietary supplements 0.9 1.2 3.5 -1.3 -1.0 -0.9 -0.5 -1.4 -0.1 -1.9 -1.3 -0.6
Breast cancer (self-reported) 0.6 0.8 3.0 -0.3 0.6 0.5 1.4 -0.6 1.7 -0.6 -0.4 -0.4
Asthma (self-reported) 0.9 1.8 3.8 0.8 1.0 -1.9 -0.6 -1.6 -1.9 -1.5 -1.2 -0.8
Osteoporosis (self-reported) 1.1 1.4 2.5 -1.6 0.2 1.5 0.4 1.5 0.3 0.8 1.6 1.4
Osteoarthritis (self-reported) 0.9 1.1 3.8 -0.1 1.9 -1.1 -1.3 0.2 -1.9 0.1 -0.1 0.1
Medication: Aspirin 1.1 1.4 3.4 0.8 -1.0 1.1 -1.0 1.8 -0.4 1.7 0.9 1.4
Medication: Gliclazide 1.6 1.8 5.6 -0.9 -0.8 -0.9 -2.4 1.6 -2.1 0.9 0.0 0.7
Illnesses of father: None of the above (group 1) 1.2 1.4 3.8 0.3 1.4 -1.3 -1.0 -0.7 -0.3 -0.5 -2.0 -1.9
Smoking status: Current 0.3 0.5 2.2 -0.2 1.5 0.9 0.1 0.3 -0.7 0.0 0.2 1.0
Forced expiratory volume in 1-second (FEV1), predicted percentage 1.4 3.0 10.2 -1.5 -1.9 1.6 2.3 -0.2 3.2 0.5 1.5 0.8
Whole body water mass 0.8 4.8 13.2 -0.2 0.6 3.6 3.3 0.5 1.4 1.2 2.8 2.6
Leg predicted mass (right) 0.8 4.4 10.8 0.2 1.9 3.1 3.3 0.1 1.4 1.0 2.9 2.0
Arm fat mass (left) 0.8 3.5 7.8 -0.5 1.5 2.8 2.2 1.2 0.9 2.0 2.6 1.7
Number of self-reported non-cancer illnesses 1.2 2.1 5.6 1.6 1.3 -1.4 -0.5 -2.0 -1.2 -2.4 -1.1 -0.6
Average weekly champagne plus white wine intake 1.2 1.7 5.6 0.2 0.9 -1.4 -0.6 -2.4 -1.0 -2.0 -1.2 -0.4
Miserableness 0.5 0.8 2.3 0.6 -0.0 -1.5 -0.3 -0.8 0.7 -0.9 -0.9 -1.3
Guilty feelings 0.5 0.8 2.9 0.0 0.7 -0.9 0.8 -0.4 0.2 -0.7 -1.2 -1.7
Wears glasses or contact lenses 1.3 1.5 4.1 0.4 -0.5 1.2 1.1 1.7 2.0 1.7 0.1 -0.8
Ever taken oral contraceptive pill 0.2 0.3 0.9 0.5 -0.9 -0.1 0.2 -0.5 0.4 0.5 0.5 -0.6
Hearing aid user 2.0 2.2 6.0 0.1 -0.5 -2.2 -0.6 -0.5 -1.5 -1.2 -2.4 -2.1
Mother’s age at death 1.0 1.2 3.6 -1.9 0.8 0.3 -1.3 1.8 0.8 0.9 -0.2 0.6
Financial situation satisfaction 0.3 0.4 0.9 -0.4 -1.0 -0.7 0.3 -0.6 -0.2 -0.8 -0.6 -0.3
Tinnitus: Yes, now most or all of the time 0.7 0.9 4.0 1.4 -0.8 -0.4 0.1 -0.1 -0.2 -0.6 -2.0 -0.7
Commuting to job workplace: Public transport 0.7 0.8 2.8 -0.8 0.6 -0.2 -1.5 0.3 -1.7 -0.0 0.5 1.0
Eye problems/disorders: Glaucoma 1.0 1.1 3.2 -1.2 1.4 -1.6 -0.2 0.1 0.1 -0.3 -0.9 -1.8
Medication: Blood pressure 0.5 1.0 2.4 -0.8 -1.5 1.2 0.4 1.4 0.2 1.2 0.3 1.1
Pain type(s) experienced in last month: Hip pain 0.5 0.7 1.9 1.0 0.6 -0.4 -0.2 -0.8 -0.7 -1.4 -1.2 -0.1
Supplements: Fish oil (including cod liver oil) 0.8 1.1 2.3 0.2 0.5 0.2 -1.4 1.5 -1.0 1.3 1.0 1.1
High cholesterol (Self-reported) 0.3 0.5 1.8 0.2 0.1 1.3 1.4 0.1 0.3 -0.2 0.4 0.7
Medication: Bendroflumethiazide 1.1 1.7 7.5 0.5 -0.4 1.6 1.0 2.7 -0.3 1.7 0.4 0.9
Medication: Paracetamol 0.2 0.4 1.1 -1.0 1.0 0.2 0.8 0.4 -0.0 0.3 0.5 0.1
Medication: Lisinopril 0.1 0.1 0.3 0.3 0.4 0.5 0.2 -0.3 -0.0 0.2 -0.5 0.5
Medication: Atorvastatin 0.4 0.4 1.5 -0.4 -1.2 -0.5 -0.1 -0.4 0.0 -0.5 -0.9 -1.0
Illnesses of father: High blood pressure 0.6 0.7 2.7 0.1 -1.0 -1.7 -0.4 -0.6 -0.4 -1.0 -0.5 -0.9
Alcohol drinker status: Never 0.5 0.6 1.4 0.3 0.8 1.2 -0.3 1.2 -0.2 0.8 0.3 1.1
Ever smoked 0.6 1.0 2.6 0.2 1.5 0.7 0.8 1.2 0.7 1.6 1.1 -0.4
Basal metabolic rate 1.0 5.3 14.0 -0.5 0.7 3.7 3.3 0.8 1.6 1.6 3.2 2.6
Leg fat percentage (left) 0.7 2.6 6.2 -0.7 0.1 2.5 1.6 1.1 1.1 1.8 2.3 1.6
Arm fat-free mass (left) 0.9 4.8 13.3 -0.8 0.1 3.6 2.6 1.0 0.9 1.4 3.1 3.0
Number of operations (self-reported) 3.2 4.7 11.2 1.6 3.4 -2.3 -0.8 -1.9 -1.5 -2.1 -2.5 -2.5
Average weekly beer plus cider intake 0.8 1.2 3.2 -0.3 0.5 0.8 -0.0 0.5 1.7 1.2 1.8 1.4
Irritability 0.9 1.5 6.5 1.5 2.5 -0.1 1.6 -0.3 0.4 -0.8 0.1 -1.1
Risk taking 2.0 2.9 8.1 1.3 0.4 -1.5 1.1 -2.9 0.6 -2.3 -1.5 -2.3
Ever had prostate specific antigen (PSA) test 3.6 4.2 8.2 -0.6 1.2 -2.5 0.1 -2.8 0.4 -2.7 -2.5 -2.9
Fractured/broken bones in last 5 years 2.1 2.7 4.4 1.7 1.5 -2.0 -0.2 -1.4 -2.1 -1.6 -1.6 -1.8
Age started oral contraceptive pill 0.1 0.1 0.3 0.2 -0.0 0.6 0.5 -0.5 0.5 0.2 -0.2 0.4
Diastolic blood pressure, automated reading 1.3 4.0 6.8 -0.7 1.7 2.6 2.4 1.9 2.0 2.3 2.3 1.4
Ever depressed for a whole week 0.7 0.9 2.7 0.1 -1.2 -1.3 -0.3 0.5 -0.5 -0.8 -1.7 -1.1
Unable to work because of sickness or disability 0.6 0.7 3.9 2.0 0.2 0.0 1.1 -0.2 0.2 -0.1 -0.3 -1.2
Commuting to job workplace: Cycle 2.3 2.8 6.8 0.0 -0.3 -2.2 -0.7 -2.2 -0.8 -2.2 -1.7 -2.6
Myopia 0.3 0.5 1.0 0.4 1.0 -0.7 -0.2 -0.7 0.0 -0.9 -0.9 -0.6
Vascular/heart problems diagnosed by doctor 0.6 1.5 4.1 0.6 1.2 -1.5 -0.4 -2.0 -0.3 -1.6 -1.1 -1.3
Cholesterol lowering medication 0.3 0.5 1.8 -0.5 -1.4 0.6 0.2 -0.3 -0.9 -0.1 0.5 0.7
Medication: Omeprazole (e.g. Zanprol) 0.6 0.8 2.4 0.3 -1.5 0.6 0.8 1.2 1.3 0.6 0.2 0.3
Pain experienced in last month 0.4 0.7 2.0 -1.4 -1.0 0.0 -0.9 1.0 0.6 0.7 0.9 0.5
Supplements: Calcium 0.5 0.6 2.9 0.8 -1.7 -0.5 -0.1 -0.2 -0.8 -0.3 -0.7 -0.1
Basal cell carcinoma (self-reported) 0.2 0.2 0.6 0.0 -0.7 -0.2 0.3 -0.8 -0.1 -0.7 -0.2 -0.5
Heart attack/myocardial infarction (self-reported) 0.7 1.0 2.6 -0.6 -0.3 0.6 -0.7 1.6 -0.2 1.6 1.2 0.9
Deep venous thrombosis (DVT) (self-reported) 0.8 1.0 2.9 0.6 -0.7 -0.0 1.3 -1.4 -0.9 -1.7 -0.9 -0.5
Heart disease (siblings) 1.7 2.1 5.7 -0.8 1.0 2.4 2.0 1.8 0.8 1.0 1.4 0.9
Alcohol drinker status: Previous 0.5 0.6 1.8 -1.2 0.2 1.0 1.3 0.3 0.4 0.1 0.9 0.3
Pack years of smoking 1.7 2.5 5.4 2.3 1.3 -0.1 1.6 -1.3 0.7 -1.5 -2.3 -1.8
Impedance of whole body 0.4 2.3 12.5 1.0 -0.1 -1.8 -3.5 1.1 -1.4 0.8 -0.4 -0.1
Leg fat mass (left) 1.2 4.6 12.0 -0.6 0.4 3.5 2.6 1.3 1.6 2.1 3.0 2.2
Arm predicted mass (left) 0.9 4.5 12.9 -0.9 0.2 3.6 2.7 0.7 0.9 1.2 2.8 3.0