Hub : Genes

P2RY14

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Lung 0.0851 0.0369 4.4e-03 0.023 NA 0.044 NA 0.002 6.3e-03 NA 2.8e-04 NA 2.0e-01
2 GTEx Thyroid 0.1420 0.0460 4.0e-04 0.007 NA 0.045 NA 0.032 8.6e-02 NA 2.4e-04 NA 1.7e-03
3 NTR Blood 0.0241 0.0091 3.5e-04 0.008 0.008 0.016 0.011 0.019 1.2e-03 1.3e-03 3.5e-06 9.8e-05 8.6e-07
4 YFS Blood 0.0926 0.0227 6.6e-15 0.051 0.053 0.061 0.067 0.065 3.5e-16 9.1e-17 4.0e-19 5.0e-21 2.0e-20
5 TCGA Kidney Renal Clear Cell Carcinoma 0.0312 0.0188 6.7e-03 0.012 0.023 0.018 NA 0.022 1.3e-02 1.1e-03 3.8e-03 NA 1.4e-03
6 TCGA Ovarian Serous Cystadenocarcinoma 0.0390 0.0250 9.8e-03 0.013 0.019 0.011 NA 0.024 4.3e-02 1.7e-02 5.3e-02 NA 8.4e-03
7 TCGA Thyroid Carcinoma 0.0840 0.0370 1.8e-05 0.016 0.040 0.044 NA 0.025 9.0e-03 9.2e-05 3.9e-05 NA 1.7e-03
8 TCGA Uterine Corpus Endometrial Carcinoma 0.1510 0.0760 3.8e-03 0.050 0.047 0.046 NA 0.034 1.6e-02 1.9e-02 2.1e-02 NA 4.0e-02

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bipolar Disorder (2018) 0.5 0.8 2.0 0.8 0.2 -0.8 -1.2 0.9 -0.6 -1.4 0.6
Bipolar Disorder or Schizophrenia 0.2 0.4 1.2 0.7 0.4 -0.8 -1.1 0.5 -0.0 -0.6 0.4
Depressed Affect (Nagel 2018) 1.7 3.6 8.5 -2.4 -2.9 1.5 1.4 -1.9 -0.7 -0.7 -2.4
Depression (Nagel 2018) 2.2 3.3 6.3 -2.4 -2.0 2.5 2.5 -1.1 0.0 -0.5 -1.8
Intelligence (Savage-Jansen 2018) 0.4 1.2 3.3 1.0 -0.7 -1.6 -1.8 0.9 -0.0 -0.6 1.1
Neuroticism (Nagel 2018) 0.5 1.1 2.9 -1.3 -1.7 0.8 1.0 -0.7 0.6 1.0 -1.1
Schizophrenia (2018) 0.1 0.1 0.2 0.2 0.3 -0.4 -0.4 -0.2 0.5 0.3 0.0
Schizophrenia vs Biploar Disorder 0.3 0.4 1.2 0.7 1.0 0.0 0.0 0.8 0.5 0.2 1.1
Worry (Nagel 2018) 0.0 0.1 0.7 0.1 0.1 0.1 -0.0 -0.1 0.0 0.8 0.2
Alzheimer’s Disease (in mother) 0.1 0.2 0.4 -0.2 0.4 -0.4 -0.6 -0.6 -0.4 0.1 -0.2
Alzheimer’s Disease (in father) 2.2 2.4 5.2 -2.0 -0.8 1.0 1.5 -2.0 -1.3 0.3 -2.3
Alzheimer’s Disease (including proxy) 1.7 2.4 6.3 -2.5 -0.9 0.7 0.8 -2.2 -1.1 -0.4 -2.2
Crohns Disease (2017) 1.6 3.6 6.1 -2.4 -2.5 0.7 0.9 -1.8 -2.1 -2.1 -1.8
Irritable Bowel Disease (IBD) 1.2 2.8 5.0 -2.1 -1.5 0.5 0.7 -1.9 -2.2 -1.7 -1.9
Ulcerative Colitis (UC) 0.4 0.8 1.8 -1.1 -0.5 0.3 0.3 -1.0 -1.2 -0.8 -1.3
Major Depression (MDD) 0.4 0.5 1.3 0.8 -0.6 -0.8 -1.1 0.1 -0.8 -0.3 0.6
Reaction Time 1.0 1.9 4.0 2.0 0.2 -1.5 -1.2 1.8 1.2 0.6 1.6
Verbal and Numeric Reasoning (VNR) 0.2 0.4 0.7 0.6 -0.8 0.8 0.3 0.6 -0.0 -0.6 0.6
Breast Cancer 0.6 1.6 5.3 -0.3 1.5 0.6 0.9 0.7 1.8 2.3 0.1
Ovarian Cancer 0.4 0.6 2.1 0.6 1.4 -0.3 -0.4 0.7 0.1 0.9 0.6
Prostate Cancer 2.2 3.1 6.9 2.4 1.2 -1.6 -1.6 2.3 0.8 -0.0 2.6
Age at First Birth 0.9 1.3 2.3 0.8 -1.0 -0.8 -0.4 1.4 1.5 1.3 1.5
Bipolar Disorder (2011) 0.9 0.9 3.7 0.1 -1.9 0.3 0.1 1.4 0.0 -0.6 1.1
Body Mass Index (BMI) (2010) 0.5 0.6 1.6 -0.2 0.4 1.3 1.3 -0.7 0.0 0.1 -1.1
Coronary Artery Disease (CAD) 0.9 1.1 1.8 -1.2 0.7 1.2 1.2 -1.3 -1.0 -0.2 -1.2
Crohns Disease (2012) 1.0 1.6 4.0 -2.0 -0.8 1.2 1.0 -1.2 -1.0 -1.1 -1.4
Mean Putamen Volume 0.9 1.0 2.4 -0.4 1.4 -0.1 0.2 -1.0 -1.6 -1.4 -0.6
Fasting Glucose 0.5 0.6 3.9 -0.4 0.1 -0.3 -0.5 -0.3 -0.7 -2.0 -0.1
HbA1C 0.7 0.8 1.5 0.7 1.0 0.6 -0.0 1.2 0.8 0.9 1.1
HDL Cholesterol 0.9 1.6 3.2 -1.4 -1.4 0.4 0.6 -1.8 -0.8 -1.3 -1.6
LDL Cholesterol 1.8 2.8 5.5 2.4 0.5 -1.8 -1.6 1.2 2.0 2.2 0.9
Lupus 2.2 3.4 5.7 -1.7 0.0 2.3 2.0 -1.6 -2.2 -2.4 -1.5
Neuroticism (2016) 0.0 0.1 0.2 0.2 -0.1 -0.0 -0.2 0.4 0.5 -0.1 -0.0
Primary Biliary Cirrhosis 0.6 0.8 4.4 -0.7 -0.3 0.7 0.6 -0.3 -0.7 -2.1 -0.0
Rheumatoid Arthritis 1.1 1.5 3.2 0.8 -0.3 1.2 1.2 1.4 1.8 1.5 0.6
Schizophrenia (2014) 0.5 1.2 3.4 0.9 -0.2 -1.5 -1.9 1.1 0.3 -0.3 1.2
Triglycerides 2.7 4.4 10.4 1.4 -0.7 0.5 0.2 3.2 2.9 2.8 2.3
Type 2 Diabetes (T2D) (2012) 0.4 0.4 1.9 1.4 -0.7 0.3 0.1 0.4 -0.3 0.2 0.6
Ulcerative Colitis 0.2 0.3 0.8 -0.3 0.9 -0.6 -0.5 -0.3 -0.7 -0.2 -0.2
Blood Eosinophil Count 1.4 10.5 26.5 2.4 -0.2 1.1 0.8 4.0 4.9 5.1 3.2
Blood Platelet Count 0.1 1.5 2.8 0.2 1.1 -1.7 -1.6 -0.8 -1.4 -1.7 -0.4
Blood Red Count 0.4 4.2 8.5 2.9 0.7 -2.2 -2.7 1.8 0.9 0.5 2.9
Blood White Count 1.8 13.7 24.3 2.5 -2.8 -4.2 -4.2 4.9 3.2 1.4 4.9
Heel T-Score 0.2 1.6 4.6 0.0 -1.2 1.2 1.1 0.7 2.1 1.9 -0.4
BMI 0.8 4.4 8.9 2.5 1.5 -1.0 -0.7 2.5 3.0 2.4 1.9
Height 0.2 3.0 4.8 -1.3 -0.3 1.9 1.0 -2.0 -2.2 -2.0 -2.2
Waist Hip Ratio (WHR) 0.4 1.7 4.0 1.4 -0.9 -2.0 -1.4 1.4 1.1 -0.2 1.3
Systolic Blood Pressure 0.7 3.3 8.2 2.7 1.1 -0.8 -1.2 2.5 0.9 0.8 2.9
Smoking Status 1.4 3.4 10.0 2.8 0.8 -0.6 -1.2 2.6 0.2 -0.4 3.2
Allergy or Eczema 1.7 4.5 11.2 -2.1 -2.6 0.6 1.0 -3.3 -1.8 -0.7 -3.0
Cardiovascular Disease 0.6 2.0 4.0 1.9 0.8 -1.5 -2.0 0.9 0.6 1.8 1.1
Hypothyroidism (self reported) 2.1 4.7 13.8 -2.4 -0.9 1.0 1.3 -3.6 -1.3 0.1 -3.7
Respiratory disease 0.2 0.6 1.2 0.1 -0.7 -0.7 -0.7 -1.1 -0.5 0.7 -0.9
Type 2 Diabetes (T2D) (2018) 0.2 0.5 0.9 -0.0 -0.3 -0.7 -0.5 0.9 0.9 0.6 0.9
Lung FEV1/FVC ratio 0.2 1.2 4.5 0.9 0.3 -2.1 -1.9 0.3 -0.0 -0.2 0.9
Lung FVC 0.9 4.6 7.9 1.8 1.1 -1.9 -1.7 2.4 2.8 2.8 2.1
Neuroticism 1.0 2.3 6.0 -1.6 -2.5 1.3 1.7 -1.3 -0.5 0.4 -1.7
Chronotype (morning person) 1.0 2.3 6.2 -0.6 -2.1 2.4 2.5 1.0 1.0 0.4 0.3
Hair Pigment 0.2 4.8 19.1 0.2 -1.7 1.1 1.4 2.4 4.4 2.1 1.8
Tanning 0.0 0.3 0.5 -0.5 0.6 0.4 0.7 0.1 -0.4 -0.7 -0.5
Hand grip strength (left) 0.3 0.8 1.3 1.0 -0.4 0.9 1.1 -0.9 0.7 0.5 -1.1
Number of treatments/medications taken 0.6 1.0 1.5 -1.1 -0.8 0.8 1.1 -1.2 -1.0 0.3 -1.2
Average weekly spirits intake 0.5 0.6 2.5 -0.2 -0.6 -0.6 -0.5 0.5 0.7 1.6 0.5
Sensitivity / hurt feelings 0.5 0.9 3.9 -0.7 -2.0 0.5 1.0 -0.1 0.9 0.9 -0.5
Frequency of depressed mood in last 2 weeks 1.0 1.4 2.6 -1.6 -1.6 0.8 0.9 -1.1 -0.2 -1.0 -1.5
Hearing difficulty/problems: Yes 0.9 1.4 3.5 -1.6 -1.1 1.7 1.9 -0.8 -0.4 -0.1 -0.7
Relative age of first facial hair 0.3 0.7 1.6 0.6 -0.8 -1.0 -1.1 0.6 -0.4 -0.2 1.2
Other serious medical condition/disability diagnosed by doctor 0.5 0.7 3.6 0.0 -1.9 -0.1 -0.1 -0.2 0.5 1.3 -0.3
Ever used hormone-replacement therapy (HRT) 3.0 3.8 8.3 2.9 0.2 -1.8 -1.8 2.5 1.2 0.5 2.8
Ever had hysterectomy (womb removed) 0.4 0.4 0.9 0.3 0.7 0.9 0.6 0.9 0.1 -0.2 0.8
Systolic blood pressure, automated reading 0.9 2.8 7.3 2.7 0.7 -1.2 -1.4 2.0 0.9 1.1 2.2
Eye problems/disorders: Diabetes related eye disease 1.8 2.0 4.1 0.8 -1.4 0.2 0.0 2.0 2.0 1.8 1.4
Angina 0.6 0.8 1.8 -1.3 -0.5 0.8 0.9 -0.5 0.8 0.9 -0.8
Medication for hormone replacement therapy 3.5 3.9 10.0 2.4 0.3 -0.2 -0.3 3.2 2.2 1.3 3.0
Vitamin and mineral supplements 1.1 1.5 6.3 -1.0 -0.0 -0.3 -0.5 -1.0 -1.6 -2.5 -1.1
Supplements: Zinc 0.8 0.8 2.0 -0.8 0.7 0.6 0.4 -1.4 -1.0 0.1 -1.4
Medication: Co-codamol 1.3 1.4 4.6 -0.2 -0.8 2.1 2.1 -0.5 -0.2 1.3 -0.3
Medication: Metformin 0.3 0.5 1.7 0.7 -1.3 0.4 0.4 0.8 0.4 0.1 0.5
Diabetes (father) 0.5 0.6 0.9 -0.1 0.9 0.9 1.0 1.0 0.8 0.7 0.1
Diabetes (mother) 2.0 2.6 3.9 1.9 1.5 -1.2 -1.2 2.0 2.0 0.6 1.9
Severe depression (siblings) 0.5 0.6 1.7 1.3 0.3 -1.0 -0.8 0.6 0.0 0.4 0.9
Pack years adult smoking proportion 0.6 0.8 2.9 0.2 -0.1 1.6 1.7 0.6 0.5 -0.2 0.8
Impedance of leg (right) 0.3 1.6 6.0 -0.2 0.7 -1.2 -1.3 -0.4 -1.6 -2.4 0.5
Leg fat-free mass (left) 0.3 1.4 3.7 1.4 -0.3 1.1 0.6 1.0 1.8 1.9 0.3
Trunk fat percentage 1.8 7.0 11.3 3.3 2.3 -1.3 -1.6 3.3 2.5 2.7 3.4
Hand grip strength (right) 0.4 1.0 2.5 0.8 1.0 0.6 0.6 -1.5 -0.7 -0.4 -1.6
Townsend deprivation index at recruitment 0.8 1.1 4.5 -0.7 -1.1 0.1 0.1 -0.2 -2.1 -1.6 0.2
Current tobacco smoking 1.0 1.6 6.2 1.4 0.5 -0.4 -0.7 1.9 0.2 -0.7 2.5
Average weekly fortified wine intake 1.2 1.3 3.0 -1.5 -0.8 0.2 0.0 -1.7 -1.0 -0.9 -1.7
Maternal smoking around birth 1.2 1.7 4.1 0.9 0.8 -1.5 -1.5 2.0 0.7 0.5 1.7
Fed-up feelings 1.3 2.3 8.8 -2.0 -3.0 0.5 0.5 -1.1 -0.5 -0.9 -1.7
Frequency of unenthusiasm / disinterest in last 2 weeks 2.5 3.4 7.8 -2.6 -2.8 1.5 1.6 -1.5 -0.7 -0.7 -2.1
Relative age voice broke 0.1 0.2 0.3 -0.2 -0.4 -0.6 -0.3 -0.1 -0.6 -0.4 0.2
Taking other prescription medications 2.6 4.0 7.9 -2.8 -2.1 1.7 2.0 -2.4 -1.4 0.1 -2.2
Age when periods started (menarche) 0.1 0.2 0.5 0.4 0.4 -0.5 -0.7 -0.1 -0.1 -0.4 0.6
Bilateral oophorectomy (both ovaries removed) 0.8 0.9 2.0 0.9 -0.4 -1.1 -1.4 0.9 0.6 0.2 1.3
Heel bone mineral density (BMD) T-score, automated (left) 0.3 0.7 3.1 0.4 -0.7 -0.3 -0.4 0.3 1.8 1.1 -0.7
Tinnitus: Yes, but not now, but have in the past 3.4 3.6 12.7 1.3 -0.2 -3.6 -3.1 1.0 0.3 -0.5 1.8
Qualifications: CSEs or equivalent 1.1 1.5 4.3 0.0 -0.8 2.1 2.1 0.3 1.0 1.0 -0.6
Serious illness, injury or assault to yourself 0.6 0.8 3.9 0.6 -0.2 -0.2 0.3 0.3 1.2 2.0 0.3
High blood pressure 1.8 5.1 9.3 3.0 1.8 -1.6 -1.9 2.2 1.4 3.0 2.5
Hayfever, allergic rhinitis or eczema 2.7 5.9 11.8 -2.5 -3.4 0.8 1.2 -3.2 -2.4 -1.8 -2.9
Multivitamins +/- minerals 1.4 1.7 4.4 2.1 0.5 -0.4 -0.5 1.4 1.1 1.6 1.8
Stomach or abdominal pain in last month 3.4 4.2 8.9 -2.1 -2.2 0.4 0.6 -3.0 -2.4 -1.7 -2.4
Supplements: Glucosamine 1.2 1.6 2.8 1.7 0.3 -1.6 -1.4 1.6 0.7 0.7 1.4
Diverticular disease/diverticulitis (self-reported) 4.2 5.0 9.2 -2.1 0.1 1.5 1.6 -3.0 -2.6 -2.7 -2.8
Medication: Atenolol 0.4 0.5 1.3 -0.6 0.4 1.0 1.1 -0.6 -0.4 -0.0 -0.9
Medication: Levothyroxine sodium 3.3 5.7 15.2 -2.7 -1.3 1.3 1.6 -3.5 -2.2 -0.5 -3.9
Sitting height 0.1 0.5 1.1 1.0 -0.7 1.0 0.3 -0.9 -0.2 0.4 -0.8
Chronic bronchitis/emphysema (father) 0.1 0.1 0.4 0.6 0.2 -0.1 -0.3 0.4 0.0 0.2 0.6
High blood pressure (mother) 0.7 0.9 2.4 0.8 1.6 -1.2 -1.1 0.3 0.3 0.4 1.2
Body mass index (BMI) 1.0 4.4 9.2 2.4 1.6 -0.7 -0.8 2.4 2.5 3.0 2.1
Impedance of leg (left) 0.4 1.7 6.5 0.0 0.9 -1.1 -1.4 -0.5 -1.7 -2.5 0.4
Leg predicted mass (left) 0.3 1.4 3.8 1.4 -0.4 1.1 0.6 0.9 1.7 1.9 0.3
Trunk fat mass 1.4 6.0 11.2 3.3 1.9 -0.8 -1.2 3.0 2.6 2.8 2.8
Waist circumference 1.1 4.0 7.3 2.7 0.8 -1.1 -1.1 2.4 2.5 2.4 2.1
Number of incorrect matches in round 0.7 1.1 3.6 1.1 1.9 -0.6 -0.5 -0.4 -1.1 -1.5 -0.2
Past tobacco smoking 0.9 1.6 3.8 -1.6 -1.9 -0.3 -0.0 -1.7 0.1 0.5 -2.0
Alcohol usually taken with meals 1.0 1.6 7.2 -0.9 -2.7 0.8 0.8 -1.0 0.5 0.7 -1.1
Nervous feelings 0.3 0.6 1.4 -1.0 0.1 1.0 1.2 -0.8 -0.7 -0.4 -0.5
Frequency of tenseness / restlessness in last 2 weeks 0.5 0.7 4.6 -0.7 -2.1 0.4 0.5 -0.1 0.2 -0.0 -0.5
Hearing difficulty/problems with background noise 0.4 0.7 2.3 -0.9 0.3 1.5 1.5 0.2 0.0 -0.1 0.1
Hair/balding pattern: Pattern 2 1.4 1.7 2.8 1.4 1.2 -1.2 -1.4 1.7 1.2 0.5 1.6
Had menopause 1.0 1.3 4.8 2.2 1.4 -0.7 -0.8 1.0 -0.1 -0.1 1.2
Had other major operations 0.9 1.1 4.6 -0.5 -2.2 -1.3 -1.3 -0.2 -0.3 0.3 0.2
Forced vital capacity (FVC) 0.2 0.8 3.9 0.6 0.2 0.5 0.3 0.8 2.0 1.0 0.2
Heel bone mineral density (BMD) T-score, automated (right) 0.4 0.9 2.8 -0.1 0.6 0.9 0.9 0.3 1.7 1.3 -0.9
Ever unenthusiastic/disinterested for a whole week 0.8 0.9 2.1 -0.8 -1.5 -0.4 0.0 -1.3 -1.1 -0.5 -1.2
Qualifications: None of the above 0.6 1.3 2.6 -0.1 0.8 1.6 1.4 1.6 0.6 -0.3 1.5
Financial difficulties in last 2 years 0.4 0.5 1.3 -0.8 0.7 1.1 1.1 -0.1 -0.5 -0.6 0.1
Mouth/teeth dental problems 0.5 0.8 2.3 -0.6 -0.4 1.5 1.4 -0.5 -0.1 -0.6 -1.0
Heart attack 0.5 0.7 1.6 0.2 -0.2 0.6 1.3 0.4 1.3 1.1 0.2
Allergy 1.6 3.6 11.8 1.9 3.4 -0.3 -0.4 2.4 1.5 0.8 2.1
Pain all over the body in last month 0.8 0.9 4.2 -0.8 -2.0 0.8 1.1 -0.2 0.1 -0.3 -0.3
Diabetes (self-reported) 0.5 0.7 2.2 0.5 -0.1 0.6 0.4 1.5 1.2 0.6 1.0
Hayfever/allergic rhinitis (self-reported) 2.0 2.7 7.0 -1.4 -1.6 -0.2 0.1 -2.6 -1.6 -1.0 -2.5
Medication: Ramipril 0.5 0.7 1.3 1.1 0.6 -0.7 -0.6 0.6 1.1 1.1 0.1
Medication: Simvastatin 0.3 0.5 2.5 -0.2 -1.6 0.5 0.7 -0.2 -0.1 0.5 -0.5
Fluid intelligence score 0.2 0.4 2.3 0.5 -0.3 1.5 0.9 0.3 0.2 -0.2 -0.1
Illnesses of siblings 0.4 0.5 1.2 -1.1 0.1 0.3 0.2 -0.6 -1.1 -0.9 -0.6
Neuroticism score 0.5 1.1 2.4 -1.5 -1.3 0.7 1.1 -1.1 -0.2 -0.1 -1.4
Weight 0.6 2.7 6.2 2.5 0.9 -0.1 -0.6 1.7 2.0 2.4 1.4
Impedance of arm (right) 0.1 0.3 0.7 -0.5 -0.6 -0.1 -0.1 0.5 -0.2 -0.8 0.8
Arm fat percentage (right) 1.4 5.4 10.4 2.4 1.3 -0.8 -0.8 3.0 2.9 3.2 2.6
Trunk fat-free mass 0.2 1.0 1.9 0.9 -1.4 1.3 0.8 -0.5 0.8 1.0 -1.2
Hip circumference 0.8 3.3 8.1 2.5 1.2 -0.8 -1.3 1.5 1.9 2.8 1.5
Time employed in main current job 0.6 0.7 3.5 1.0 1.9 0.3 0.2 -0.0 -0.3 1.0 0.1
Alcohol intake versus 10 years previously 0.2 0.3 1.0 -0.3 -1.0 0.8 0.7 0.2 -0.4 -0.1 0.1
Father’s age at death 0.3 0.3 1.3 0.4 -1.1 -0.1 -0.4 -0.6 0.1 0.6 -0.6
Worrier / anxious feelings 0.1 0.3 0.7 -0.6 0.2 0.2 0.8 -0.6 -0.3 -0.0 -0.6
Frequency of tiredness / lethargy in last 2 weeks 2.5 4.0 18.7 -2.2 -4.3 1.0 1.4 -1.2 0.2 1.1 -1.6
Falls in the last year 0.1 0.1 0.4 0.5 -0.4 -0.6 -0.2 0.1 0.4 0.1 -0.1
Hair/balding pattern: Pattern 3 0.3 0.5 2.8 -0.2 1.7 -0.2 -0.1 0.3 0.4 0.8 0.0
Number of live births 1.0 1.5 4.4 -0.2 -0.2 -0.9 -0.8 -2.0 -1.3 -0.0 -2.1
Forced expiratory volume in 1-second (FEV1) 0.2 0.6 2.6 0.8 0.5 0.0 -0.1 0.5 1.6 1.1 0.2
Pulse rate 0.3 0.6 1.1 0.8 1.0 0.5 0.5 1.0 0.8 0.4 0.6
Happiness 2.1 2.6 5.0 -1.9 -2.2 0.0 0.2 -1.9 -1.4 -1.3 -2.2
Noisy workplace 2.0 2.5 4.8 -2.2 -0.5 1.5 1.5 -1.3 -1.3 -2.2 -1.4
Qualifications: A levels/AS levels or equivalent 0.8 1.7 7.2 1.1 -0.8 -2.7 -2.2 -0.3 0.1 0.0 -0.2
Serious illness, injury or assault of a close relative in last 2 years 0.5 0.6 1.5 1.0 -0.3 -1.0 -1.2 -0.3 -1.1 0.1 0.2
Mouth/teeth dental problems: Dentures 0.2 0.3 1.1 -0.7 -0.9 -0.3 -0.1 0.1 -1.0 -0.6 -0.1
Asthma 0.3 0.6 1.7 0.7 -0.9 -1.0 -1.3 0.2 0.2 0.8 0.4
Medication: Ibuprofen (e.g. Nurofen) 0.4 0.5 1.0 -0.8 -1.0 0.7 0.9 -0.8 -0.3 0.2 -0.7
Medication: Cholesterol lowering 1.0 1.6 3.7 -1.3 -0.2 1.8 1.9 -1.2 -0.0 1.0 -1.4
Depression (self-reported) 0.3 0.4 0.8 -0.7 -0.6 -0.6 -0.2 -0.7 -0.8 0.1 -0.9
Medication: Lansoprazole 4.2 4.8 6.7 -2.1 -1.4 2.6 2.6 -2.0 -2.5 -2.4 -1.7
Prospective memory result 0.7 0.8 2.2 0.2 -1.4 -1.5 -1.3 0.2 0.3 -0.6 0.2
Lung cancer (father) 0.7 0.9 5.4 0.7 2.3 0.2 -0.2 0.4 -0.3 0.0 0.8
Illnesses of mother 1.5 1.8 4.9 -0.7 -1.2 1.3 1.5 -0.3 1.3 2.2 -1.4
Forced expiratory volume in 1-second (FEV1), Best measure 0.3 0.8 3.0 1.0 0.4 -0.1 -0.3 1.1 1.7 0.9 0.8
Pulse wave Arterial Stiffness index 0.5 0.6 2.2 0.9 1.5 -0.9 -0.3 -0.5 0.4 0.3 0.1
Impedance of arm (left) 0.1 0.6 2.3 -0.8 -0.1 -0.4 -0.3 0.4 -0.7 -1.5 1.1
Arm fat mass (right) 1.2 4.8 9.5 2.6 1.2 -0.6 -0.8 2.6 2.8 3.1 2.2
Trunk predicted mass 0.2 1.0 1.8 0.9 -1.4 1.3 0.8 -0.5 0.8 1.0 -1.2
Standing height 0.1 0.8 1.4 0.6 -1.1 0.9 0.1 -1.1 -0.7 -1.1 -1.2
Length of working week for main job 2.3 2.5 7.4 1.0 -0.1 -0.6 -0.7 1.8 2.7 2.5 1.3
Exposure to tobacco smoke at home 0.3 0.4 1.3 -0.3 -0.1 -0.1 -0.0 -0.7 -0.8 -1.2 -0.5
Breastfed as a baby 0.4 0.5 1.3 -1.2 0.4 0.6 0.9 -0.9 0.3 0.5 -0.8
Tense / ‘highly strung’ 0.5 0.8 2.1 0.4 0.7 0.3 -0.0 1.3 1.4 0.7 1.2
Seen doctor (GP) for nerves, anxiety, tension or depression 0.4 0.7 1.7 -0.6 -1.2 0.4 0.9 -1.0 -0.0 -0.2 -1.3
Hair/balding pattern: Pattern 4 0.9 2.3 4.7 1.1 2.2 -0.9 -1.2 1.4 1.9 1.5 1.5
Birth weight of first child 0.2 0.3 0.6 0.4 -0.7 -0.5 -0.6 0.8 0.7 -0.4 0.1
Peak expiratory flow (PEF) 0.2 0.5 1.0 0.5 0.3 -1.0 -0.7 -0.7 0.3 0.9 -0.8
Pulse wave reflection index 0.1 0.2 0.6 -0.1 0.1 -0.3 0.3 -0.8 -0.0 0.8 -0.3
Ever highly irritable/argumentative for 2 days 0.8 1.0 1.9 1.0 -0.9 -1.2 -1.0 0.5 1.1 1.4 0.6
Loud music exposure frequency 1.2 1.3 3.7 -0.2 -1.3 1.7 1.9 0.8 1.2 0.6 0.1
Qualifications: O levels/GCSEs or equivalent 0.3 0.5 1.4 1.2 -0.5 -0.8 -0.8 0.5 0.5 0.5 0.7
Mouth/teeth dental problems: Bleeding gums 2.3 3.0 4.2 1.7 2.1 -1.3 -1.9 1.7 1.7 1.4 1.9
Blood clot in the leg (DVT) 0.2 0.2 0.5 -0.4 -0.7 0.0 -0.1 -0.7 -0.6 0.3 -0.4
Medication: Paracetamol 0.5 0.8 1.9 -1.4 -0.3 -0.7 -0.2 -1.2 -0.4 -0.9 -1.4
Headache pain in last month 0.6 1.1 2.1 -1.4 -1.3 0.0 0.5 -1.4 -0.7 -0.8 -1.2
Medication for cholesterol, blood pressure or diabetes 1.1 1.8 6.5 -0.1 -0.9 -1.5 -1.5 -0.5 -1.6 -2.5 0.1
Glaucoma (self-reported) 2.9 3.4 6.8 -1.2 -1.4 -2.4 -2.6 -1.5 -2.2 -1.9 -0.8
Gout (self-reported) 0.4 0.5 1.2 -0.1 -0.5 -1.1 -0.9 0.5 0.8 -0.2 0.9
Hypothyroidism/myxoedema (self-reported) 1.8 3.4 10.3 -2.3 -0.5 0.4 0.8 -3.1 -1.2 0.2 -3.2
Medication: Amlodipine 0.7 1.0 3.1 1.2 1.8 -1.1 -1.0 0.5 0.4 0.5 0.8
Medication: Ventolin 100micrograms inhaler 0.7 1.0 2.9 -0.4 -1.7 0.7 0.8 -1.3 -1.1 -0.3 -0.8
Birth weight 0.5 1.0 2.2 -0.7 0.1 1.5 1.4 -0.8 -1.0 -1.1 -1.0
Chronic bronchitis/emphysema (mother) 2.7 3.2 7.1 -2.5 -1.6 0.6 0.3 -1.4 -2.2 -2.7 -1.5
High blood pressure (siblings) 1.9 2.8 6.8 2.6 0.2 -0.9 -1.0 1.9 1.7 1.9 1.9
Forced vital capacity (FVC), Best measure 0.1 0.5 2.5 0.6 0.1 0.2 0.0 0.7 1.6 0.7 0.2
Body fat percentage 1.7 6.7 10.8 3.3 2.2 -1.3 -1.6 3.2 2.5 2.6 3.2
Leg fat percentage (right) 1.5 5.5 9.9 3.1 2.1 -1.9 -2.1 2.7 1.9 1.9 2.8
Arm fat-free mass (right) 0.2 0.8 2.8 1.7 -0.1 0.9 0.3 0.0 1.0 1.3 -0.4
Exposure to tobacco smoke outside home 0.8 1.1 2.9 0.7 0.9 -1.2 -1.2 0.4 -0.9 -1.7 0.8
Comparative body size at age 10 0.4 1.2 3.9 -0.6 0.0 1.0 1.5 0.2 1.4 2.0 -0.5
Number of full brothers 0.6 0.7 1.7 0.7 1.3 -1.3 -0.6 0.7 0.7 0.5 0.7
Worry too long after embarrassment 0.2 0.3 1.3 -0.3 0.8 -0.4 -0.1 -0.3 0.1 1.1 -0.5
Seen a psychiatrist for nerves, anxiety, tension or depression 0.9 1.1 3.3 -0.0 0.2 -1.5 -1.2 -0.7 -1.8 -1.3 -0.1
Wheeze or whistling in the chest in last year 0.5 0.8 3.2 -1.3 -1.8 0.5 0.3 -0.2 -0.1 1.1 -0.2
Number of children fathered 0.3 0.3 1.3 -0.7 -1.2 0.1 0.1 0.1 0.6 -0.5 0.0
Reason for reducing amount of alcohol drunk: Health precaution 0.3 0.4 1.0 0.2 0.2 1.0 1.0 -0.2 -0.2 -0.9 -0.2
Age at first live birth 0.5 0.9 2.4 -0.4 0.5 -1.6 -1.4 -1.2 -0.6 -0.2 -0.8
Pulse wave peak to peak time 0.5 0.5 1.4 -0.9 -1.2 1.0 0.4 0.3 -0.6 -0.6 -0.3
Health satisfaction 0.7 0.9 1.5 -1.1 -0.9 -0.7 -0.4 -1.2 -0.9 -0.7 -1.2
Shortness of breath walking on level ground 0.3 0.4 1.0 -0.1 -0.7 0.7 0.9 0.2 1.0 0.3 0.0
Qualifications: College or University degree 0.2 0.6 2.4 0.0 -0.0 -1.6 -1.1 -0.7 -0.2 -0.2 -0.8
Eye problems/disorders: None of the above 0.4 0.5 1.4 0.4 0.4 -1.2 -0.8 -0.7 -0.6 -0.7 0.2
Mouth/teeth dental problems: Loose teeth 0.7 0.9 1.6 1.1 0.6 0.7 0.5 1.2 0.6 1.3 1.1
Emphysema/chronic bronchitis 0.4 0.5 1.7 -0.2 0.1 0.6 0.9 -0.5 0.7 1.3 -0.5
Medication for pain relief, constipation, heartburn 1.2 2.0 3.8 2.0 0.7 -1.1 -1.4 1.6 1.4 1.1 1.7
Neck or shoulder pain in last month 2.3 3.3 11.0 -3.3 -2.8 0.8 0.9 -1.4 -0.8 -0.9 -1.6
Medication: Blood pressure 1.3 2.3 6.3 1.2 1.8 0.6 0.6 1.4 1.8 2.5 1.0
Angina (self-reported) 0.4 0.5 1.3 -1.1 -0.6 0.5 0.7 -0.1 1.1 0.8 -0.4
Migraine (self-reported) 0.7 0.9 1.8 -1.1 -0.0 0.4 0.6 -1.3 -1.1 -0.9 -1.1
Medication: Ibuprofen 0.5 0.6 1.1 -1.1 -1.0 0.5 0.8 -1.0 -0.2 -0.1 -0.7
Medication: Allopurinol 0.4 0.5 1.6 0.3 0.4 -0.9 -0.6 0.8 0.2 -0.8 1.3
Medication: Omeprazole 1.8 2.1 7.0 -2.4 -2.6 0.4 0.3 -1.2 -0.5 -0.3 -1.5
Medication: Seretide 50 evohaler 1.6 1.8 4.4 -1.1 -1.9 2.1 2.0 -0.7 -0.3 0.5 -0.8
Mean time to correctly identify matches 1.3 2.5 4.5 2.1 1.0 -1.5 -1.1 2.1 1.3 0.5 2.1
Heart disease (mother) 1.5 1.8 3.5 -1.7 -1.9 0.7 0.4 -1.3 -1.7 -1.4 -1.0
Reproduciblity of spirometry measurement using ERS/ATS criteria 1.6 1.9 3.9 2.0 0.5 0.2 0.4 1.4 1.5 2.0 1.6
Whole body fat mass 1.4 6.0 10.6 3.2 1.9 -0.9 -1.2 3.0 2.7 2.8 2.7
Leg fat mass (right) 1.4 5.5 10.2 3.2 1.9 -1.2 -1.4 2.8 2.4 2.5 2.6
Arm predicted mass (right) 0.2 1.1 2.8 1.7 -0.3 1.1 0.5 0.3 1.4 1.6 -0.3
Pulse rate, automated reading 0.6 2.1 4.8 1.3 1.4 -0.2 -0.1 2.2 1.7 0.9 2.1
Alcohol intake frequency. 0.6 1.4 3.8 -1.3 -0.7 1.7 1.9 -0.7 -1.2 0.4 -0.8
Comparative height size at age 10 0.0 0.3 0.9 0.1 0.1 1.0 0.2 -0.5 0.0 -0.3 -0.8
Number of full sisters 1.4 1.7 3.1 -0.9 0.9 1.4 1.8 -1.3 -1.2 -1.2 -1.5
Suffer from ‘nerves’ 0.2 0.3 0.7 0.5 -0.9 0.1 0.2 0.6 0.5 0.7 0.5
Overall health rating 0.9 1.9 5.4 -1.6 -2.3 1.4 1.8 -0.4 0.4 0.7 -1.0
Chest pain or discomfort 0.2 0.3 0.5 -0.6 -0.7 0.3 0.5 -0.5 -0.2 -0.5 -0.6
Had major operations 0.9 1.0 2.6 -1.1 -0.1 1.4 1.6 -1.0 -0.2 0.3 -1.2
Age at last live birth 0.9 1.4 3.0 -0.2 0.5 -1.2 -1.0 -1.7 -1.7 -1.1 -1.0
Family relationship satisfaction 0.2 0.2 0.4 -0.5 0.6 0.5 -0.1 -0.6 -0.3 -0.4 -0.7
Leg pain on walking 0.4 0.5 1.5 0.2 -1.2 -0.5 -0.1 0.5 1.0 1.0 -0.2
Qualifications: NVQ or HND or HNC or equivalent 0.3 0.4 1.0 -0.3 -0.4 -0.7 -0.4 -1.0 -0.1 0.6 -0.9
Commuting to job workplace: Car/motor vehicle 1.4 1.6 3.9 1.0 -0.8 0.2 0.2 1.8 2.0 1.5 1.4
Illness, injury, bereavement, stress in last 2 years 0.2 0.2 0.6 0.5 0.5 0.1 -0.0 0.7 0.6 -0.1 0.7
Medication: Aspirin 0.0 0.1 0.2 0.1 0.0 0.3 0.3 0.2 0.0 0.4 -0.1
Supplements: Vitamin C 0.4 0.5 3.1 -0.2 0.3 0.1 0.1 0.1 0.9 1.8 0.1
Knee pain experienced in last month 1.6 2.4 5.3 -2.3 -2.1 2.0 1.9 -0.8 -0.5 -0.6 -0.9
Hypertension (Self-reported) 1.3 3.5 6.3 2.4 1.4 -1.6 -2.0 1.7 1.0 2.5 2.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 6.6 7.8 20.8 -4.6 -1.2 2.5 2.6 -3.2 -2.0 -1.5 -3.2
Illnesses of father: Heart disease 0.6 0.8 2.3 -1.5 -1.0 0.8 1.4 -0.4 0.6 0.0 -0.8
Illnesses of siblings: Diabetes 0.4 0.5 1.4 -0.8 -1.0 -0.3 -0.2 -0.8 0.1 0.7 -1.2
Smoking status: Previous 1.0 1.5 3.8 1.4 2.0 0.1 0.1 1.6 0.6 0.3 1.7
Forced expiratory volume in 1-second (FEV1), predicted 0.4 0.7 5.2 -0.0 -2.3 0.3 0.3 -0.2 0.4 0.5 -0.4
Whole body fat-free mass 0.2 1.0 2.0 1.1 -0.9 1.3 0.8 0.1 1.2 1.4 -0.6
Leg fat-free mass (right) 0.2 1.3 3.5 1.3 -0.4 1.4 0.8 0.7 1.5 1.9 0.1
Arm fat percentage (left) 1.4 5.7 9.3 2.6 1.5 -0.9 -0.9 3.0 2.8 3.1 2.9
Average weekly red wine intake 1.6 2.3 5.2 -2.1 -1.4 0.6 0.7 -2.2 -0.9 -0.5 -2.3
Handedness (chirality/laterality): Left-handed 1.0 1.2 3.8 1.1 -0.4 0.5 0.1 1.6 1.9 0.6 1.2
Mood swings 1.1 2.0 5.9 -2.0 -2.4 1.4 1.3 -0.9 -0.3 -0.3 -1.3
Loneliness, isolation 0.3 0.4 1.3 0.1 -0.7 0.1 0.1 0.9 1.1 0.3 0.6
Long-standing illness, disability or infirmity 1.9 2.8 5.1 -1.9 -2.3 1.8 2.1 -1.5 -0.7 0.5 -1.8
Ever had bowel cancer screening 0.7 0.8 1.8 -1.4 -1.2 0.6 1.0 -0.7 -0.1 0.2 -1.0
Diabetes diagnosed by doctor 0.4 0.6 1.6 0.7 -0.4 -0.2 -0.2 1.2 1.3 0.8 0.9
Ever had stillbirth, spontaneous miscarriage or termination 0.6 0.6 2.2 -0.6 -1.5 0.1 -0.4 -0.7 -0.8 -0.2 -1.1
Friendships satisfaction 0.1 0.1 0.1 -0.2 -0.3 0.2 0.1 0.1 0.4 0.4 -0.0
Qualifications: nursing, teaching 1.1 1.8 5.6 0.4 -2.1 -1.1 -0.9 -0.2 1.2 2.4 -0.7
Commuting to job workplace: Walk 3.2 3.5 7.9 -2.4 -2.8 0.4 1.0 -2.0 -1.0 -1.3 -2.5
Eye problems/disorders: Cataract 0.7 0.8 2.3 0.3 0.4 1.2 0.9 1.5 1.1 0.7 0.5
Mouth/teeth dental problems: Mouth ulcers 0.2 0.3 1.2 -0.8 -1.1 -0.3 0.0 -0.4 -0.1 -0.3 0.4
Medication for cholesterol 2.6 3.9 9.8 -2.5 0.8 1.3 1.5 -2.5 -1.4 -1.5 -3.1
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.4 0.5 0.9 -0.6 0.2 0.3 0.2 -0.8 -0.9 -0.9 -1.0
Back pain experienced in last month 0.6 0.8 3.0 -0.6 -1.7 1.2 1.2 -0.1 0.1 0.6 0.0
Mineral and other dietary supplements 2.6 3.4 6.2 -2.4 -0.7 1.2 1.0 -2.2 -1.9 -2.5 -2.0
Breast cancer (self-reported) 0.1 0.1 0.3 -0.3 0.3 -0.6 -0.5 0.1 -0.1 -0.3 0.2
Asthma (self-reported) 0.3 0.6 1.6 0.6 -1.2 -1.0 -1.3 0.2 0.1 0.6 0.3
Osteoporosis (self-reported) 0.9 1.1 3.1 0.3 -0.7 -1.8 -1.5 -0.1 -1.4 -0.9 0.3
Osteoarthritis (self-reported) 0.2 0.3 1.0 0.1 -1.0 0.8 0.4 -0.4 -0.4 -0.4 -0.4
Medication: Aspirin 0.1 0.1 0.4 0.3 -0.1 0.1 0.0 0.6 0.4 0.6 0.2
Medication: Gliclazide 1.4 1.6 5.2 0.3 -2.3 0.5 0.3 0.9 1.5 1.6 1.2
Illnesses of father: None of the above (group 1) 0.9 1.1 2.4 1.2 1.6 -0.1 -0.7 1.4 -0.1 -0.4 1.5
Smoking status: Current 0.8 1.3 4.3 1.2 0.4 -0.5 -0.9 1.5 -0.3 -1.0 2.1
Forced expiratory volume in 1-second (FEV1), predicted percentage 1.0 2.2 5.2 0.6 0.6 -1.9 -1.6 1.4 2.3 1.4 1.2
Whole body water mass 0.2 1.1 2.0 1.2 -1.0 1.3 0.8 0.1 1.2 1.4 -0.7
Leg predicted mass (right) 0.3 1.4 3.6 1.3 -0.4 1.4 0.8 0.7 1.7 1.9 0.0
Arm fat mass (left) 1.3 5.3 10.5 2.8 1.4 -0.6 -0.8 2.7 2.9 3.2 2.3
Number of self-reported non-cancer illnesses 1.5 2.5 6.7 -1.9 -2.6 1.0 1.4 -1.5 -0.9 0.6 -1.8
Average weekly champagne plus white wine intake 0.4 0.6 1.5 0.4 0.7 -1.2 -0.8 -0.5 -0.5 -1.1 -0.4
Miserableness 2.9 5.0 11.7 -2.8 -2.4 0.2 0.7 -2.9 -1.8 -1.4 -3.4
Guilty feelings 0.3 0.5 2.1 -0.3 -0.4 0.0 0.5 0.3 1.4 1.1 -0.4
Wears glasses or contact lenses 0.4 0.4 1.5 0.2 0.2 -0.6 -0.5 0.8 0.4 0.7 1.2
Ever taken oral contraceptive pill 0.7 0.8 1.6 -0.7 -0.9 1.0 1.1 -0.6 0.3 1.2 -0.9
Hearing aid user 0.8 0.9 1.7 -1.0 -1.3 0.8 1.1 -0.7 -0.6 0.6 -1.2
Mother’s age at death 0.6 0.7 1.6 1.3 -0.4 -0.2 -0.4 0.7 1.0 1.2 0.9
Financial situation satisfaction 2.3 2.9 5.9 -2.1 -1.2 -0.2 -0.2 -1.9 -2.4 -2.1 -1.9
Tinnitus: Yes, now most or all of the time 0.0 0.0 0.1 -0.2 0.2 0.3 0.2 0.2 -0.3 -0.1 0.2
Commuting to job workplace: Public transport 0.8 1.0 3.4 0.6 1.1 -1.3 -0.9 -0.0 -0.6 -1.8 0.1
Eye problems/disorders: Glaucoma 1.4 1.7 2.5 -1.4 -1.1 -1.3 -1.6 -1.1 -1.4 -1.5 -1.0
Medication: Blood pressure 1.1 2.2 4.5 1.8 0.1 -1.6 -2.0 1.3 0.4 1.0 2.1
Pain type(s) experienced in last month: Hip pain 0.7 0.9 2.6 -0.3 0.3 1.6 1.6 0.1 1.0 0.7 -0.6
Supplements: Fish oil (including cod liver oil) 3.0 3.9 6.8 2.4 0.7 -1.8 -1.6 2.4 1.9 2.6 1.9
High cholesterol (Self-reported) 0.2 0.4 2.2 0.0 -1.5 0.4 0.4 -0.6 -0.4 0.3 -0.5
Medication: Bendroflumethiazide 0.5 0.8 2.2 0.9 -0.2 -1.4 -1.5 -0.2 -0.3 1.2 -0.0
Medication: Paracetamol 0.5 0.8 2.0 -1.4 0.2 -0.3 0.0 -1.3 -0.3 -0.6 -1.4
Medication: Lisinopril 0.8 1.0 2.4 0.5 1.0 -1.0 -1.6 0.5 -0.6 -1.3 1.1
Medication: Atorvastatin 0.7 0.8 3.1 -0.1 0.3 -0.2 -0.3 -1.1 -1.8 -1.4 -0.3
Illnesses of father: High blood pressure 0.5 0.7 1.8 0.3 0.8 -0.6 -0.7 -1.3 -0.9 0.7 -0.8
Alcohol drinker status: Never 0.7 0.8 2.9 0.0 0.3 1.0 1.0 0.8 1.0 1.7 -0.0
Ever smoked 0.6 1.1 3.8 1.0 0.8 -0.0 -0.3 1.4 -0.3 -1.2 1.9
Basal metabolic rate 0.2 1.3 3.1 1.6 -0.5 1.0 0.5 0.7 1.6 1.8 -0.0
Leg fat percentage (left) 1.6 5.8 11.2 3.4 2.2 -2.0 -2.3 2.6 1.9 1.9 2.8
Arm fat-free mass (left) 0.3 1.5 4.0 1.9 0.0 1.1 0.5 0.5 1.6 2.0 -0.3
Number of operations (self-reported) 0.9 1.4 3.4 -1.5 -1.8 0.4 0.6 -1.4 -0.8 0.2 -1.5
Average weekly beer plus cider intake 0.5 0.7 1.6 0.5 0.7 0.4 0.3 1.2 1.0 -0.6 1.2
Irritability 0.2 0.4 1.1 -0.7 0.8 -0.3 -0.1 -0.7 -0.3 -1.0 -0.4
Risk taking 0.3 0.5 1.2 0.9 0.5 -0.1 -0.2 0.6 0.9 1.1 0.6
Ever had prostate specific antigen (PSA) test 0.4 0.4 1.4 -1.2 -0.8 0.5 0.6 -0.4 -0.3 -0.0 -0.8
Fractured/broken bones in last 5 years 0.4 0.5 1.1 0.6 -1.1 -0.9 -0.8 0.3 0.2 0.0 0.9
Age started oral contraceptive pill 0.5 0.6 2.3 0.1 -0.1 0.3 0.3 -1.5 -1.0 -0.2 -1.3
Diastolic blood pressure, automated reading 1.3 4.1 8.7 2.9 1.2 -2.3 -2.5 1.9 1.0 1.4 2.2
Ever depressed for a whole week 1.1 1.4 4.0 0.1 0.0 -2.0 -1.9 -0.7 -1.4 -1.0 -0.0
Unable to work because of sickness or disability 2.3 3.0 5.7 1.6 0.0 -2.1 -1.9 2.2 1.4 0.9 2.4
Commuting to job workplace: Cycle 0.5 0.6 2.8 -0.7 -1.7 -0.5 -0.1 -0.6 0.2 0.5 -0.8
Myopia 0.4 0.6 1.4 0.8 1.0 -0.5 -0.4 0.7 0.3 1.0 1.2
Vascular/heart problems diagnosed by doctor 1.1 2.9 6.8 -2.3 -1.3 0.8 1.1 -1.7 -1.4 -2.6 -1.7
Cholesterol lowering medication 1.2 1.8 3.6 1.6 -1.9 -1.4 -1.5 1.1 -0.1 -0.5 1.5
Medication: Omeprazole (e.g. Zanprol) 3.1 3.7 10.6 -3.1 -3.2 1.1 1.1 -1.6 -0.8 -0.4 -2.0
Pain experienced in last month 2.9 4.8 8.5 2.9 2.9 -1.8 -2.3 2.0 1.4 1.5 2.1
Supplements: Calcium 0.6 0.6 2.2 -0.1 -1.5 0.8 0.6 -0.9 -0.9 -0.2 -0.2
Basal cell carcinoma (self-reported) 0.5 0.6 1.4 0.9 -0.4 -1.0 -0.9 -0.0 0.5 1.2 -0.1
Heart attack/myocardial infarction (self-reported) 0.6 0.8 2.4 0.4 -0.0 0.5 1.1 0.5 1.6 1.4 0.2
Deep venous thrombosis (DVT) (self-reported) 0.1 0.1 0.4 -0.2 -0.6 -0.1 -0.3 -0.5 -0.5 0.3 -0.1
Heart disease (siblings) 0.5 0.6 1.5 -0.8 -0.3 -0.5 -0.2 -1.2 -0.8 -0.9 -0.9
Alcohol drinker status: Previous 2.3 2.7 4.2 -2.0 -2.0 1.3 1.6 -1.6 -1.6 -1.3 -1.4
Pack years of smoking 0.4 0.5 1.7 0.1 -0.3 1.2 1.3 0.6 0.4 -0.2 0.6
Impedance of whole body 0.2 1.0 3.8 -0.2 0.7 -0.8 -0.8 0.3 -1.0 -2.0 1.1
Leg fat mass (left) 1.4 5.3 10.6 3.2 1.9 -1.1 -1.4 2.7 2.4 2.4 2.6
Arm predicted mass (left) 0.3 1.6 4.2 2.1 -0.1 0.9 0.3 0.6 1.7 2.1 -0.1