TWAS hub - PAFAH1B3

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Artery Tibial	0.059	0.0322	0.0049	0.021	NA	0.033	NA	0.026	0.0081	NA	0.0012	NA	0.0035
2	TCGA	Thyroid Carcinoma	0.020	0.0150	0.0040	0.006	0.018	0.014	NA	0.011	0.0850	0.0067	0.0140	NA	0.0270

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Relative age of first facial hair	5.9	12.2	23.8	-0.8	-4.9
Hair/balding pattern: Pattern 4	5.4	13.1	19.8	2.5	4.5
Ever unenthusiastic/disinterested for a whole week	5.0	6.1	7.6	2.8	2.1
Ever depressed for a whole week	5.0	6.2	8.8	3.0	1.9
Ever highly irritable/argumentative for 2 days	4.5	5.4	9.6	1.1	3.1
Heart disease (mother)	4.2	5.2	9.7	-3.1	-0.8
Major Depression (MDD)	4.1	4.9	9.7	3.1	-0.3
Blood White Count	4.0	29.9	57.5	-1.6	7.6
Breast Cancer	3.9	9.3	12.3	3.5	-2.5
Exposure to tobacco smoke outside home	3.8	5.1	7.8	1.5	2.8
Handedness (chirality/laterality): Left-handed	3.8	4.6	9.0	3.0	0.3
Rheumatoid Arthritis	3.7	5.1	10.2	0.2	3.2
Ever used hormone-replacement therapy (HRT)	3.7	4.7	4.8	-2.2	2.1
Pack years of smoking	3.7	5.4	7.8	1.7	2.8
Illnesses of siblings: Diabetes	3.6	4.4	6.3	-2.5	-1.6
Tinnitus: Yes, now most or all of the time	3.5	4.1	7.0	1.1	2.7
Medication: Ibuprofen (e.g. Nurofen)	3.4	4.3	8.2	-0.7	2.9
Noisy workplace	3.2	3.9	5.4	1.5	2.3
Tinnitus: Yes, but not now, but have in the past	3.1	3.3	3.7	1.9	1.7
Medication: Ibuprofen	3.1	3.8	6.8	-0.8	2.6
Pack years adult smoking proportion	3.0	4.6	5.5	1.9	2.3
Osteoporosis (self-reported)	3.0	3.7	6.6	-0.9	-2.6
Waist Hip Ratio (WHR)	2.9	13.2	26.4	-0.1	-5.1
Family relationship satisfaction	2.9	3.6	5.8	2.4	1.2
Forced vital capacity (FVC)	2.7	10.4	20.9	0.1	-4.6
Happiness	2.7	3.2	5.0	2.2	1.2
Irritability	2.7	4.5	8.1	-0.9	2.8
Friendships satisfaction	2.6	3.2	6.3	2.5	0.3
Leg fat percentage (left)	2.6	9.4	14.4	-2.1	3.8
Age at First Birth	2.5	3.7	4.6	1.6	2.1
Height	2.5	48.8	97.2	0.5	-9.9
Taking other prescription medications	2.5	3.9	6.4	2.5	1.2
Heel bone mineral density (BMD) T-score, automated (right)	2.5	5.6	7.4	2.7	2.0
Forced vital capacity (FVC), Best measure	2.5	9.2	18.4	0.1	-4.3
Emphysema/chronic bronchitis	2.4	2.7	5.3	0.3	2.3
Hearing aid user	2.4	2.7	3.3	1.5	1.8
Shortness of breath walking on level ground	2.3	2.8	5.1	2.3	0.6
Body Mass Index (BMI) (2010)	2.2	3.1	6.1	0.2	2.5
Blood Eosinophil Count	2.2	17.1	25.4	-3.0	5.0
Hearing difficulty/problems with background noise	2.2	3.5	3.8	-2.0	1.8
Time employed in main current job	2.2	2.6	4.4	0.8	-2.1
Forced expiratory volume in 1-second (FEV1), Best measure	2.2	6.9	13.7	0.3	-3.7
High blood pressure (siblings)	2.2	3.1	5.6	0.8	2.4
Leg fat percentage (right)	2.2	7.9	13.1	-1.6	3.6
Alcohol intake frequency.	2.1	5.0	8.8	1.1	-3.0
Basal cell carcinoma (self-reported)	2.1	2.5	3.0	-1.7	1.4
Bipolar Disorder (2018)	2.0	3.2	5.3	2.3	-1.0
Allergy or Eczema	2.0	5.3	8.3	1.5	2.9
Medication: Ventolin 100micrograms inhaler	2.0	2.6	4.5	2.1	0.8
Eye problems/disorders: Cataract	2.0	2.3	4.0	-2.0	-0.8
Unable to work because of sickness or disability	2.0	2.6	4.9	0.5	2.2
Chronotype (morning person)	1.9	4.4	8.3	0.8	-2.9
Medication for hormone replacement therapy	1.9	2.1	4.2	2.0	-0.2
Vitamin and mineral supplements	1.9	2.5	3.9	-2.0	-1.1
Allergy	1.9	4.3	5.5	-1.8	-2.4
Medication: Simvastatin	1.8	2.7	4.0	-2.0	-1.2
Forced expiratory volume in 1-second (FEV1)	1.8	6.1	12.2	-0.2	-3.5
Financial situation satisfaction	1.8	2.3	3.2	1.8	1.1
Schizophrenia vs Biploar Disorder	1.7	2.3	2.9	-1.7	1.3
Frequency of unenthusiasm / disinterest in last 2 weeks	1.7	2.2	2.9	1.7	1.2
Qualifications: CSEs or equivalent	1.7	2.3	2.3	-1.5	1.5
Body fat percentage	1.7	6.8	9.6	-2.0	3.1
Migraine (self-reported)	1.7	2.1	3.8	1.9	-0.7
Qualifications: nursing, teaching	1.7	2.6	5.1	-0.3	-2.3
Prostate Cancer	1.6	2.2	4.4	-0.3	-2.1
Schizophrenia (2014)	1.6	3.5	6.4	0.8	2.5
Triglycerides	1.6	2.5	4.8	2.2	-0.5
Illnesses of siblings	1.6	2.2	4.1	-0.6	-2.0
Standing height	1.6	15.7	29.8	1.2	-5.5
Blood Platelet Count	1.5	16.9	33.4	-0.7	5.8
Lung FVC	1.5	7.9	13.8	-1.4	-3.7
Diabetes (father)	1.5	1.8	3.4	1.8	0.5
Diabetes (self-reported)	1.5	2.3	4.6	-2.1	-0.2
Wheeze or whistling in the chest in last year	1.5	2.7	4.4	0.9	2.1
Age at last live birth	1.5	2.1	4.3	-0.1	-2.1
Hypertension (Self-reported)	1.5	4.3	6.5	-1.4	2.5
Average weekly red wine intake	1.5	2.1	2.3	-1.4	-1.5
Number of self-reported non-cancer illnesses	1.5	2.7	4.7	2.2	-0.8
Pain type(s) experienced in last month: Hip pain	1.5	1.9	3.8	-1.9	0.2
Commuting to job workplace: Cycle	1.5	1.8	3.2	1.8	-0.6
Bipolar Disorder or Schizophrenia	1.4	3.3	6.1	2.5	0.7
Trunk fat percentage	1.4	5.6	6.6	-2.2	2.6
Multivitamins +/- minerals	1.4	1.8	2.6	1.6	1.0
Hair/balding pattern: Pattern 2	1.4	1.8	2.0	1.4	1.3
Had menopause	1.4	1.7	3.2	-1.8	-0.4
Medication: Paracetamol	1.4	2.2	3.1	1.2	1.8
Medication: Paracetamol	1.4	2.1	3.4	0.9	1.8
Deep venous thrombosis (DVT) (self-reported)	1.4	1.8	2.2	1.2	1.5
Fasting Glucose	1.3	1.6	3.0	1.7	-0.4
LDL Cholesterol	1.3	2.0	3.2	0.9	-1.8
Hearing difficulty/problems: Yes	1.3	2.0	2.8	1.1	1.7
Current tobacco smoking	1.3	2.1	4.3	-0.2	2.1
Blood clot in the leg (DVT)	1.3	1.6	1.7	1.3	1.3
Had major operations	1.3	1.5	3.0	1.7	0.1
Leg pain on walking	1.3	1.6	3.2	-0.1	1.8
Arm fat percentage (left)	1.3	5.2	7.0	-1.8	2.6
Loneliness, isolation	1.3	1.8	2.3	1.5	1.1
Osteoarthritis (self-reported)	1.3	1.7	2.6	-0.9	-1.6
Medication: Aspirin	1.3	1.7	2.2	-1.1	-1.5
Alcohol drinker status: Never	1.3	1.5	2.3	0.9	-1.5
Schizophrenia (2018)	1.2	2.4	3.2	1.3	1.8
Sitting height	1.2	8.2	15.7	-0.8	-4.0
Pain all over the body in last month	1.2	1.3	2.2	1.5	0.7
Arm fat percentage (right)	1.2	4.8	7.3	-1.5	2.7
Medication: Aspirin	1.2	1.6	2.2	-1.5	-1.0
Knee pain experienced in last month	1.2	1.9	2.2	-1.2	-1.5
Guilty feelings	1.2	1.8	3.1	0.7	1.8
Medication: Lisinopril	1.2	1.5	3.0	-1.7	0.2
Ulcerative Colitis (UC)	1.1	2.2	2.6	1.6	1.3
Ulcerative Colitis	1.1	1.6	2.2	1.0	1.5
Heel bone mineral density (BMD) T-score, automated (left)	1.1	2.6	3.3	1.8	1.4
High blood pressure	1.1	2.9	4.4	-1.2	2.1
Hayfever, allergic rhinitis or eczema	1.1	2.3	3.9	0.9	2.0
Body mass index (BMI)	1.1	4.6	8.7	-0.7	2.9
Frequency of tiredness / lethargy in last 2 weeks	1.1	1.7	3.1	1.8	0.7
Length of working week for main job	1.1	1.2	1.6	0.9	-1.3
Tense / ‘highly strung’	1.1	1.8	3.0	-0.9	1.7
Pulse wave reflection index	1.1	1.4	2.8	0.0	1.7
Mouth/teeth dental problems: Bleeding gums	1.1	1.4	1.8	1.3	1.1
Birth weight	1.1	2.4	3.1	1.3	-1.8
Neck or shoulder pain in last month	1.1	1.6	2.9	-0.5	1.7
Medication: Blood pressure	1.1	2.0	2.3	-1.3	1.5
Miserableness	1.1	1.9	3.1	1.8	-0.8
Myopia	1.1	1.7	2.2	-1.5	-1.0
Leg fat mass (left)	1.1	4.3	7.2	-1.2	2.7
Number of incorrect matches in round	1.0	1.6	2.6	-0.8	1.6
Pulse wave peak to peak time	1.0	1.2	1.8	-0.8	-1.3
Eye problems/disorders: None of the above	1.0	1.2	1.3	1.1	1.1
Leg fat mass (right)	1.0	3.9	6.8	-1.0	2.6
Smoking status: Current	1.0	1.5	3.1	-0.0	1.8
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.0	2.1	4.0	-0.5	-2.0
Medication: Bendroflumethiazide	1.0	1.5	2.1	-0.9	1.5
Illnesses of father: High blood pressure	1.0	1.2	1.4	-1.0	1.2
BMI	0.9	5.1	10.2	-0.3	3.2
Type 2 Diabetes (T2D) (2018)	0.9	1.6	3.2	-1.8	0.2
Diabetes (mother)	0.9	1.1	1.8	-1.4	-0.7
Chronic bronchitis/emphysema (father)	0.9	1.0	1.9	1.4	-0.4
Alcohol usually taken with meals	0.9	1.4	2.9	0.2	-1.7
Medication: Ramipril	0.9	1.1	1.9	0.6	1.4
Comparative height size at age 10	0.9	5.0	9.8	0.3	-3.1
Average weekly beer plus cider intake	0.9	1.3	1.7	0.9	1.3
Lupus	0.8	1.2	2.2	1.5	-0.3
Heel T-Score	0.8	6.5	12.2	0.8	3.5
Respiratory disease	0.8	1.8	3.3	0.6	1.8
Number of treatments/medications taken	0.8	1.4	2.4	1.5	0.6
Other serious medical condition/disability diagnosed by doctor	0.8	1.1	2.0	1.4	0.3
Qualifications: O levels/GCSEs or equivalent	0.8	1.3	1.9	-1.4	0.8
Headache pain in last month	0.8	1.4	2.3	1.5	-0.7
Health satisfaction	0.8	1.1	1.3	1.1	0.9
Medication for pain relief, constipation, heartburn	0.8	1.4	2.4	-0.6	-1.6
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.8	1.0	1.9	-1.4	-0.2
Whole body fat mass	0.8	3.3	5.2	-1.2	2.3
Illness, injury, bereavement, stress in last 2 years	0.8	1.0	1.9	0.3	-1.4
Breast cancer (self-reported)	0.8	1.0	2.0	0.1	-1.4
Depressed Affect (Nagel 2018)	0.7	1.6	2.9	1.7	-0.4
Depression (Nagel 2018)	0.7	1.1	2.2	1.5	-0.1
Ever had hysterectomy (womb removed)	0.7	0.8	1.2	-1.1	0.7
Trunk fat mass	0.7	2.9	3.3	-1.6	1.8
Trunk fat-free mass	0.7	4.1	4.7	1.9	-2.2
Mouth/teeth dental problems: Dentures	0.7	1.2	2.4	-1.5	0.3
Asthma	0.7	1.4	1.6	1.1	1.3
Trunk predicted mass	0.7	4.0	4.6	1.9	-2.1
Reason for reducing amount of alcohol drunk: Health precaution	0.7	0.9	1.1	-1.1	0.8
Qualifications: College or University degree	0.7	2.3	4.4	2.1	-0.4
Mouth/teeth dental problems: Loose teeth	0.7	0.8	1.3	-0.5	-1.1
Number of full sisters	0.7	0.9	1.7	0.4	1.3
Overall health rating	0.7	1.5	3.0	-0.1	1.7
Diabetes diagnosed by doctor	0.7	1.1	1.6	-1.3	-0.8
Arm fat mass (left)	0.7	2.7	3.8	-1.3	1.9
Risk taking	0.7	1.0	1.9	1.4	0.1
Irritable Bowel Disease (IBD)	0.6	1.5	1.7	1.3	1.1
Blood Red Count	0.6	6.1	7.4	2.2	2.7
Average weekly spirits intake	0.6	0.7	1.2	-1.1	0.5
Hand grip strength (right)	0.6	1.7	3.2	0.5	-1.8
Hayfever/allergic rhinitis (self-reported)	0.6	0.8	1.4	0.5	-1.2
Hip circumference	0.6	2.7	5.1	-0.6	2.3
Pulse rate	0.6	1.0	2.0	-1.4	0.1
Medication: Lansoprazole	0.6	0.7	1.2	0.4	-1.1
Pulse wave Arterial Stiffness index	0.6	0.7	0.8	0.9	0.8
Arm fat mass (right)	0.6	2.5	3.9	-1.0	2.0
Loud music exposure frequency	0.6	0.6	1.1	-0.5	1.0
Glaucoma (self-reported)	0.6	0.8	1.5	0.1	1.2
Gout (self-reported)	0.6	0.8	1.1	1.1	-0.6
Suffer from ‘nerves’	0.6	1.0	1.9	0.1	1.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.6	0.7	1.4	1.2	-0.0
Medication: Blood pressure	0.6	1.1	1.6	-1.3	0.7
Supplements: Calcium	0.6	0.7	1.1	0.5	1.0
HbA1C	0.5	0.6	1.1	1.0	-0.2
Townsend deprivation index at recruitment	0.5	0.7	1.3	1.2	0.0
Diverticular disease/diverticulitis (self-reported)	0.5	0.6	1.3	-1.1	-0.1
Frequency of tenseness / restlessness in last 2 weeks	0.5	0.8	1.6	0.3	1.3
Medication for cholesterol, blood pressure or diabetes	0.5	0.9	1.3	0.7	-1.2
Worry too long after embarrassment	0.5	0.8	1.0	-1.0	-0.7
Supplements: Vitamin C	0.5	0.6	1.0	0.5	1.0
Whole body fat-free mass	0.5	2.7	3.0	1.5	-1.7
Whole body water mass	0.5	2.9	3.4	1.5	-1.9
Eye problems/disorders: Glaucoma	0.5	0.5	1.1	0.0	1.0
Age started oral contraceptive pill	0.5	0.6	0.7	0.7	0.8
Alcohol drinker status: Previous	0.5	0.6	0.9	0.9	-0.5
Worry (Nagel 2018)	0.4	0.8	1.5	0.3	1.2
HDL Cholesterol	0.4	0.7	1.2	-1.1	0.4
Cardiovascular Disease	0.4	1.2	2.3	-0.3	1.5
Hand grip strength (left)	0.4	1.0	1.3	1.1	-0.9
Systolic blood pressure, automated reading	0.4	1.1	1.7	-0.7	1.3
Eye problems/disorders: Diabetes related eye disease	0.4	0.5	1.0	-0.0	-1.0
Angina	0.4	0.5	1.1	-0.1	-1.0
Medication: Atenolol	0.4	0.5	1.0	1.0	0.2
Qualifications: None of the above	0.4	0.8	0.8	0.9	0.9
Neuroticism score	0.4	0.8	1.3	0.6	1.1
Father’s age at death	0.4	0.5	0.9	0.4	0.9
Falls in the last year	0.4	0.5	0.8	0.9	0.4
Lung cancer (father)	0.4	0.4	0.8	0.1	0.9
Impedance of arm (left)	0.4	2.0	3.0	-1.7	-1.0
Number of full brothers	0.4	0.5	0.9	-0.2	1.0
Angina (self-reported)	0.4	0.6	1.1	-0.2	-1.1
Pulse rate, automated reading	0.4	1.4	2.6	-1.6	0.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.4	0.5	1.0	-0.0	-1.0
Asthma (self-reported)	0.4	0.8	1.2	0.6	1.1
Wears glasses or contact lenses	0.4	0.5	0.7	-0.9	-0.4
Mother’s age at death	0.4	0.5	0.7	0.5	0.9
Ever had prostate specific antigen (PSA) test	0.4	0.5	1.0	1.0	0.0
Vascular/heart problems diagnosed by doctor	0.4	1.1	1.5	1.2	-0.9
Cholesterol lowering medication	0.4	0.6	0.6	-0.8	-0.8
Impedance of whole body	0.4	1.9	3.7	-1.9	-0.4
Alzheimer’s Disease (in mother)	0.3	0.3	0.5	-0.7	-0.3
Coronary Artery Disease (CAD)	0.3	0.3	0.6	-0.8	0.0
Mean Putamen Volume	0.3	0.3	0.4	0.7	-0.4
Hypothyroidism (self reported)	0.3	0.7	1.0	0.6	-1.0
Hair Pigment	0.3	7.2	13.0	1.1	-3.6
Severe depression (siblings)	0.3	0.3	0.5	-0.7	0.4
Relative age voice broke	0.3	0.4	0.6	-0.8	-0.5
Age when periods started (menarche)	0.3	0.6	0.7	0.7	-0.9
High blood pressure (mother)	0.3	0.4	0.8	-0.3	0.9
Impedance of leg (left)	0.3	1.6	2.9	-1.7	0.5
Had other major operations	0.3	0.4	0.6	0.8	0.3
Fluid intelligence score	0.3	0.6	1.0	0.4	-1.0
Worrier / anxious feelings	0.3	0.6	1.1	1.1	0.4
Hair/balding pattern: Pattern 3	0.3	0.4	0.8	-0.9	-0.2
Illnesses of mother	0.3	0.4	0.7	0.8	-0.4
Hypothyroidism/myxoedema (self-reported)	0.3	0.6	0.8	0.6	-0.9
Commuting to job workplace: Car/motor vehicle	0.3	0.4	0.7	0.3	-0.8
Forced expiratory volume in 1-second (FEV1), predicted	0.3	0.6	1.2	0.1	-1.1
Leg fat-free mass (right)	0.3	1.4	2.3	0.7	-1.5
Mood swings	0.3	0.5	0.7	0.6	0.8
Mineral and other dietary supplements	0.3	0.4	0.8	-0.1	0.9
Medication: Gliclazide	0.3	0.3	0.7	-0.8	-0.1
Leg predicted mass (right)	0.3	1.4	2.2	0.7	-1.5
Medication: Omeprazole (e.g. Zanprol)	0.3	0.4	0.5	0.7	-0.6
Alzheimer’s Disease (in father)	0.2	0.2	0.4	0.2	0.6
Crohns Disease (2017)	0.2	0.5	0.9	0.9	0.2
Crohns Disease (2012)	0.2	0.4	0.7	0.9	-0.2
Neuroticism (2016)	0.2	0.4	0.7	-0.1	-0.8
Primary Biliary Cirrhosis	0.2	0.4	0.4	0.6	0.6
Systolic Blood Pressure	0.2	1.0	1.3	-0.8	1.1
Tanning	0.2	2.2	2.9	-1.2	1.7
Sensitivity / hurt feelings	0.2	0.3	0.5	0.3	0.7
Medication: Co-codamol	0.2	0.2	0.4	0.7	-0.1
Medication: Metformin	0.2	0.2	0.4	-0.1	-0.6
Leg fat-free mass (left)	0.2	1.2	1.6	1.0	-1.3
Average weekly fortified wine intake	0.2	0.2	0.2	0.5	-0.4
Supplements: Glucosamine	0.2	0.2	0.2	0.5	-0.5
Leg predicted mass (left)	0.2	1.3	1.7	0.9	-1.3
Mouth/teeth dental problems	0.2	0.4	0.7	-0.1	-0.9
Alcohol intake versus 10 years previously	0.2	0.3	0.6	0.0	-0.8
Prospective memory result	0.2	0.3	0.5	0.7	-0.0
Peak expiratory flow (PEF)	0.2	0.4	0.7	-0.3	-0.8
Medication: Amlodipine	0.2	0.3	0.5	0.7	-0.3
Arm fat-free mass (right)	0.2	1.0	1.2	0.8	-1.1
Number of children fathered	0.2	0.2	0.4	-0.6	-0.4
Medication: Seretide 50 evohaler	0.2	0.3	0.5	-0.3	0.7
Arm predicted mass (right)	0.2	1.2	1.8	0.7	-1.3
Chest pain or discomfort	0.2	0.2	0.4	0.7	-0.2
Qualifications: NVQ or HND or HNC or equivalent	0.2	0.3	0.4	0.6	0.4
Illnesses of father: Heart disease	0.2	0.3	0.6	-0.8	0.0
Smoking status: Previous	0.2	0.3	0.4	0.4	-0.7
Long-standing illness, disability or infirmity	0.2	0.3	0.4	0.5	-0.7
Ever had stillbirth, spontaneous miscarriage or termination	0.2	0.2	0.3	0.5	0.4
Commuting to job workplace: Walk	0.2	0.3	0.3	-0.5	-0.5
Mouth/teeth dental problems: Mouth ulcers	0.2	0.4	0.7	0.8	-0.2
Illnesses of father: None of the above (group 1)	0.2	0.2	0.3	0.5	-0.3
Ever taken oral contraceptive pill	0.2	0.2	0.4	-0.6	0.0
Supplements: Fish oil (including cod liver oil)	0.2	0.3	0.6	0.1	-0.8
High cholesterol (Self-reported)	0.2	0.4	0.7	-0.2	-0.8
Basal metabolic rate	0.2	1.2	1.4	1.0	-1.2
Arm fat-free mass (left)	0.2	0.8	1.0	1.0	-0.9
Pain experienced in last month	0.2	0.3	0.6	-0.7	0.1
Arm predicted mass (left)	0.2	0.9	1.2	1.1	-0.8
Intelligence (Savage-Jansen 2018)	0.1	0.2	0.3	0.6	-0.0
Neuroticism (Nagel 2018)	0.1	0.3	0.3	0.5	0.6
Alzheimer’s Disease (including proxy)	0.1	0.2	0.3	-0.5	0.3
Verbal and Numeric Reasoning (VNR)	0.1	0.2	0.3	0.1	-0.6
Ovarian Cancer	0.1	0.1	0.2	0.2	-0.5
Smoking Status	0.1	0.3	0.5	0.4	0.7
Neuroticism	0.1	0.2	0.2	0.3	0.5
Frequency of depressed mood in last 2 weeks	0.1	0.2	0.2	0.4	0.4
Supplements: Zinc	0.1	0.1	0.1	0.2	0.3
Impedance of leg (right)	0.1	0.6	1.1	-1.1	0.2
Maternal smoking around birth	0.1	0.1	0.2	-0.0	0.4
Fed-up feelings	0.1	0.2	0.3	0.1	-0.6
Serious illness, injury or assault to yourself	0.1	0.1	0.3	0.0	-0.5
Stomach or abdominal pain in last month	0.1	0.1	0.2	0.1	0.5
Medication: Levothyroxine sodium	0.1	0.1	0.3	-0.5	-0.2
Nervous feelings	0.1	0.2	0.3	-0.3	0.6
Impedance of arm (right)	0.1	0.4	0.5	-0.7	-0.5
Number of live births	0.1	0.1	0.2	0.4	-0.1
Medication: Cholesterol lowering	0.1	0.2	0.2	-0.4	-0.4
Depression (self-reported)	0.1	0.1	0.2	0.5	0.2
Exposure to tobacco smoke at home	0.1	0.1	0.2	-0.1	-0.4
Breastfed as a baby	0.1	0.2	0.3	0.1	0.5
Birth weight of first child	0.1	0.2	0.4	-0.2	-0.6
Seen a psychiatrist for nerves, anxiety, tension or depression	0.1	0.1	0.3	-0.5	0.0
Age at first live birth	0.1	0.2	0.3	-0.4	-0.6
Medication: Allopurinol	0.1	0.1	0.1	0.4	-0.4
Mean time to correctly identify matches	0.1	0.2	0.4	-0.6	0.0
Medication for cholesterol	0.1	0.1	0.1	0.3	-0.4
Average weekly champagne plus white wine intake	0.1	0.2	0.3	-0.5	0.3
Commuting to job workplace: Public transport	0.1	0.1	0.2	-0.1	0.4
Medication: Atorvastatin	0.1	0.1	0.3	0.1	0.5
Ever smoked	0.1	0.2	0.4	0.2	0.6
Fractured/broken bones in last 5 years	0.1	0.2	0.4	-0.6	0.1
Diastolic blood pressure, automated reading	0.1	0.4	0.7	-0.4	0.8
Heart attack/myocardial infarction (self-reported)	0.1	0.1	0.2	-0.4	-0.0
Reaction Time	0.0	0.1	0.2	-0.0	-0.4
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0
Type 2 Diabetes (T2D) (2012)	0.0	0.0	0.0	-0.2	0.0
Lung FEV1/FVC ratio	0.0	0.2	0.5	0.1	-0.7
Bilateral oophorectomy (both ovaries removed)	0.0	0.0	0.0	0.1	0.0
Waist circumference	0.0	0.2	0.3	-0.3	0.5
Past tobacco smoking	0.0	0.1	0.1	-0.0	0.4
Financial difficulties in last 2 years	0.0	0.1	0.1	0.3	0.2
Heart attack	0.0	0.0	0.0	-0.2	0.1
Weight	0.0	0.1	0.1	-0.1	0.4
Qualifications: A levels/AS levels or equivalent	0.0	0.0	0.0	0.0	-0.0
Serious illness, injury or assault of a close relative in last 2 years	0.0	0.0	0.1	0.0	0.3
Seen doctor (GP) for nerves, anxiety, tension or depression	0.0	0.0	0.0	-0.0	0.2
Chronic bronchitis/emphysema (mother)	0.0	0.1	0.1	0.1	0.3
Comparative body size at age 10	0.0	0.0	0.1	0.3	0.1
Medication: Omeprazole	0.0	0.0	0.1	0.2	0.1
Ever had bowel cancer screening	0.0	0.0	0.0	-0.2	-0.1
Back pain experienced in last month	0.0	0.0	0.0	0.1	-0.1
Number of operations (self-reported)	0.0	0.0	0.0	0.1	0.0
Heart disease (siblings)	0.0	0.1	0.1	-0.3	-0.1

Hub : Genes

PAFAH1B3

Models

Trait associations