Hub : Genes

PAK1

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.0670 0.0260 2.9e-04 0.043 0.019 0.046 0.025 0.032 4.7e-06 2.1e-03 2.6e-06 4.5e-04 7.6e-05
2 GTEx Artery Aorta 0.1060 0.0410 9.5e-04 0.129 NA 0.076 NA 0.110 1.4e-07 NA 5.4e-05 NA 1.2e-06
3 GTEx Artery Coronary 0.1520 0.0620 2.8e-03 0.018 NA -0.007 NA 0.013 8.0e-02 NA 6.6e-01 NA 1.1e-01
4 GTEx Artery Tibial 0.1719 0.0412 6.6e-10 0.129 NA 0.197 NA 0.196 2.8e-10 NA 2.4e-15 NA 2.9e-15
5 GTEx Esophagus Mucosa 0.2880 0.0660 2.3e-11 0.148 NA 0.210 NA 0.207 4.4e-10 NA 4.3e-14 NA 7.1e-14
6 GTEx Testis 0.1710 0.0640 5.4e-04 0.096 NA 0.074 NA 0.088 5.0e-05 NA 3.3e-04 NA 9.8e-05
7 GTEx Thyroid 0.5830 0.0610 1.7e-16 0.194 NA 0.216 NA 0.249 8.6e-15 NA 1.7e-16 NA 5.0e-19
8 GTEx Uterus 0.3340 0.1000 3.1e-04 0.042 NA 0.099 NA 0.086 5.0e-02 NA 4.9e-03 NA 8.3e-03
9 METSIM Adipose 0.0802 0.0286 6.5e-06 0.030 0.040 0.034 0.040 0.023 2.3e-05 1.2e-06 6.7e-06 1.2e-06 1.8e-04
10 NTR Blood 0.0177 0.0098 7.7e-03 -0.001 0.004 0.003 0.004 0.000 7.0e-01 1.2e-02 3.8e-02 1.1e-02 2.7e-01
11 ROSMAP Brain Pre-frontal Cortex 0.0970 0.0329 8.1e-07 0.045 0.047 0.024 0.048 0.031 1.5e-06 9.5e-07 4.3e-04 7.3e-07 6.4e-05
12 YFS Blood 0.1826 0.0458 3.4e-07 0.028 0.018 0.034 0.035 0.025 1.8e-09 9.7e-07 1.8e-11 1.3e-11 1.2e-08
13 TCGA Prostate Adenocarcinoma 0.0595 0.0379 7.1e-04 0.022 0.024 0.010 NA 0.024 1.9e-03 1.4e-03 2.7e-02 NA 1.5e-03
14 TCGA Thyroid Carcinoma 0.0430 0.0330 8.2e-03 0.013 0.019 0.003 NA 0.025 1.6e-02 5.4e-03 1.6e-01 NA 1.5e-03

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
Bipolar Disorder (2018) 0.4 0.7 2.9 0.2 -0.2 -1.0 -0.4 0.2 0.3 -0.4 -0.6 -0.2 -1.7 0.5 -1.4 1.6 -0.0
Bipolar Disorder or Schizophrenia 0.1 0.1 0.5 -0.1 -0.2 -0.4 0.0 -0.1 0.0 -0.4 0.0 0.7 0.3 0.4 0.3 0.7 -0.4
Depressed Affect (Nagel 2018) 0.6 1.3 5.7 0.9 -0.8 -1.7 -1.0 -1.0 -0.2 -0.1 -0.3 0.5 -1.5 -0.3 -1.8 2.4 0.3
Depression (Nagel 2018) 1.8 2.7 5.3 1.6 -0.8 -1.2 -1.9 -2.0 -0.1 2.0 -0.9 -1.1 -2.0 1.5 -1.9 1.9 2.3
Intelligence (Savage-Jansen 2018) 0.6 1.8 5.6 2.2 0.5 0.6 -0.6 -1.6 -0.8 2.4 -1.0 -1.1 -0.8 2.1 -0.7 -0.1 1.7
Neuroticism (Nagel 2018) 1.5 3.5 7.7 2.3 -0.9 -1.9 -1.9 -2.0 -0.2 1.2 -1.4 -1.1 -2.8 1.6 -2.6 2.8 1.5
Schizophrenia (2018) 0.3 0.6 3.4 -0.3 -0.0 0.2 0.3 -0.3 -0.2 -0.2 0.6 1.1 1.8 0.1 1.5 -0.4 -0.5
Schizophrenia vs Biploar Disorder 1.4 1.8 7.7 -0.2 1.2 1.3 1.1 0.2 -2.0 -0.4 0.6 0.8 2.8 -0.2 1.8 -2.0 -0.9
Worry (Nagel 2018) 1.4 3.0 6.3 2.5 -1.0 -1.5 -1.8 -1.6 -0.1 1.4 -2.0 -1.5 -1.8 1.9 -2.0 2.2 1.7
Alzheimer’s Disease (in mother) 0.3 0.3 2.8 -0.3 -0.0 0.4 -0.0 -0.1 -0.3 -0.4 0.7 0.5 1.7 0.5 -0.2 -0.5 0.1
Alzheimer’s Disease (in father) 0.6 0.7 3.6 0.2 1.0 0.9 -0.0 0.1 -0.0 1.5 0.2 -0.5 -1.9 0.2 -0.5 -0.4 1.0
Alzheimer’s Disease (including proxy) 0.1 0.1 0.4 -0.1 -0.1 0.4 -0.3 -0.2 0.1 0.3 0.5 0.3 0.4 0.5 0.1 -0.2 0.6
Crohns Disease (2017) 0.1 0.3 0.8 -0.4 -0.6 -0.6 -0.5 -0.3 0.5 0.9 -0.7 0.1 -0.6 0.1 0.6 0.3 0.5
Irritable Bowel Disease (IBD) 0.2 0.4 1.2 -0.2 -0.6 -0.7 -0.6 -0.6 0.8 1.1 -0.5 0.0 -0.9 -0.0 0.7 0.3 0.6
Ulcerative Colitis (UC) 0.2 0.4 1.7 0.2 -0.3 -0.8 -0.5 -0.8 0.4 0.7 -0.5 -0.0 -1.3 0.0 0.4 0.5 0.6
Major Depression (MDD) 0.7 0.8 2.7 0.2 -0.8 -0.5 -0.9 -0.3 0.2 0.7 0.2 -0.1 -1.6 1.4 -1.1 1.3 1.1
Reaction Time 0.7 1.3 5.5 0.5 1.4 0.7 0.3 -0.5 1.1 2.3 -0.3 -1.7 -1.8 0.2 -0.9 -0.4 1.2
Verbal and Numeric Reasoning (VNR) 0.9 2.0 5.6 2.2 1.2 1.4 -0.3 -0.9 -0.9 2.4 -0.6 -1.2 -1.4 2.2 -1.3 -0.4 1.7
Breast Cancer 1.1 2.7 6.3 -2.4 2.5 1.5 2.2 1.5 0.8 -0.4 1.6 1.1 -0.6 -2.3 0.4 -2.1 -1.5
Ovarian Cancer 0.7 0.9 2.9 0.7 -1.7 -0.9 -1.5 -0.8 0.2 0.3 -1.2 -0.4 1.0 1.2 -0.1 0.9 0.8
Prostate Cancer 0.5 0.8 1.8 -0.6 -0.6 -1.0 -0.6 0.0 1.3 -0.8 -1.4 -1.3 -0.8 -1.2 0.2 0.4 -0.6
Age at First Birth 0.6 0.9 3.3 0.9 -0.6 0.1 -1.0 -1.3 -1.1 1.1 -0.3 -0.3 1.0 1.8 0.3 -0.1 1.3
Bipolar Disorder (2011) 0.6 0.6 4.1 -0.6 1.0 0.6 0.3 0.3 0.6 1.0 0.6 0.1 -2.0 0.6 -0.3 0.2 0.3
Body Mass Index (BMI) (2010) 0.5 0.7 2.6 -0.8 -1.0 -1.6 -1.1 -0.9 1.1 -0.8 0.1 0.0 -0.9 -0.2 -0.0 1.1 0.4
Coronary Artery Disease (CAD) 1.4 1.7 4.8 -1.4 0.6 0.5 1.6 1.8 0.0 -1.7 0.8 1.9 0.9 -1.4 0.1 -0.6 -2.2
Crohns Disease (2012) 1.1 1.8 4.3 -1.3 1.2 1.5 1.6 1.1 -0.2 -0.6 1.4 2.1 0.9 -1.2 1.9 -1.7 -1.3
Mean Putamen Volume 0.7 0.8 2.7 0.1 -1.1 -1.6 -0.5 0.8 0.3 -0.2 -1.0 -0.6 -0.3 0.4 -1.4 1.5 0.2
Fasting Glucose 0.3 0.4 1.8 -0.2 0.1 -0.3 0.2 -0.0 0.1 -0.5 0.0 0.8 1.0 -1.4 0.8 -0.7 -0.3
HbA1C 0.4 0.4 2.6 -0.9 -0.2 0.3 0.1 0.3 0.5 -0.5 1.6 0.6 0.7 -0.2 0.3 -0.5 0.3
HDL Cholesterol 0.9 1.4 7.1 -1.3 -0.3 -0.2 0.8 0.2 -0.1 -1.6 0.6 1.6 2.7 -2.0 0.2 -0.4 -0.9
LDL Cholesterol 0.4 0.6 2.4 -0.5 0.4 0.5 0.2 0.0 -0.3 -0.7 1.5 1.1 1.3 0.3 1.4 -0.4 -0.2
Lupus 0.8 1.2 3.4 -1.1 0.7 1.3 1.2 1.8 0.7 -1.1 -0.1 0.9 0.6 -1.1 0.8 -1.4 -1.5
Neuroticism (2016) 0.4 0.5 1.9 0.7 0.9 1.4 0.6 0.2 -1.0 0.4 0.9 1.1 0.2 -0.1 0.7 -0.5 0.1
Primary Biliary Cirrhosis 0.2 0.3 3.1 0.5 -0.4 -0.2 -0.4 0.4 -0.4 0.3 -0.5 -0.2 -0.2 1.8 -0.1 -0.1 0.8
Rheumatoid Arthritis 0.4 0.6 2.6 -0.2 -0.2 -1.6 -0.7 -1.6 -0.2 0.0 -0.8 -0.2 -0.3 -0.5 -0.7 0.5 1.0
Schizophrenia (2014) 0.3 0.7 2.0 0.6 -0.2 -0.3 -0.6 -1.4 -1.2 1.0 0.6 -0.1 0.7 1.1 1.4 0.3 1.0
Triglycerides 0.2 0.3 0.9 0.7 0.3 -0.2 -0.2 -0.3 0.2 0.4 0.6 -1.0 -0.6 0.9 0.6 -0.7 0.5
Type 2 Diabetes (T2D) (2012) 0.6 0.7 2.6 -1.1 0.1 -0.9 0.0 -0.4 0.0 -1.3 1.6 0.7 0.8 -1.2 0.4 0.0 -0.7
Ulcerative Colitis 1.0 1.5 3.8 1.4 -1.3 -1.3 -1.7 -2.0 -0.5 1.1 -0.8 -0.4 -1.0 0.8 0.9 1.1 1.5
Blood Eosinophil Count 0.7 5.7 20.7 -2.6 -0.1 -0.8 1.8 2.5 1.1 -4.2 0.9 2.4 2.1 -4.5 0.3 -0.1 -3.5
Blood Platelet Count 1.3 14.9 34.2 3.2 -3.8 -5.2 -4.9 -5.1 -0.5 2.2 -3.7 -2.9 -4.8 1.4 -1.7 5.8 4.1
Blood Red Count 0.1 0.7 3.1 -1.8 -1.2 -1.1 -0.6 0.4 1.0 -0.1 -0.6 0.2 0.1 0.0 -0.7 1.4 0.4
Blood White Count 0.2 1.7 5.5 -0.2 -1.6 -1.7 -1.5 -1.1 1.5 -0.4 -2.3 -1.5 -0.6 -0.1 -0.3 2.0 0.3
Heel T-Score 0.8 6.5 19.4 2.4 -3.5 -4.4 -3.4 -2.6 -2.4 0.5 -2.7 -1.9 -0.8 0.6 -1.1 3.6 1.9
BMI 0.8 4.5 11.5 -2.4 1.2 0.7 2.2 0.9 0.1 -2.9 2.3 2.0 0.9 -3.4 2.7 -1.3 -3.4
Height 0.9 16.8 34.0 -5.7 3.1 4.4 4.7 5.8 2.3 -3.0 3.3 3.4 5.3 -2.4 1.0 -5.1 -4.5
Waist Hip Ratio (WHR) 0.3 1.4 4.5 0.2 -0.9 -1.6 -1.0 -1.3 2.1 0.4 -2.1 -0.7 -1.8 -0.3 -0.2 0.9 0.4
Systolic Blood Pressure 0.3 1.6 7.0 -1.6 -0.2 -0.1 0.8 0.6 0.7 -1.9 -0.3 2.6 0.8 -1.1 1.8 -0.3 -1.6
Smoking Status 0.4 1.1 4.7 -1.2 -0.4 -1.1 0.2 0.9 0.5 -2.2 -0.8 0.9 0.3 -1.7 -0.5 0.8 -1.1
Allergy or Eczema 1.2 3.2 9.9 1.2 -1.5 -1.7 -1.9 -2.2 -1.7 1.4 -0.5 -0.2 -1.5 1.3 -2.1 3.1 2.5
Cardiovascular Disease 0.5 1.8 10.6 -1.1 -0.1 -1.2 0.3 -0.2 1.5 -1.5 -1.3 1.2 -0.6 -3.2 0.0 0.2 -1.9
Hypothyroidism (self reported) 0.4 0.9 5.7 -0.4 -0.8 -1.1 -0.2 0.2 -0.8 -0.7 -0.9 0.5 -0.7 -0.6 -2.4 1.2 -0.6
Respiratory disease 0.9 2.1 6.4 1.5 -1.3 -1.7 -1.8 -2.2 -1.1 0.7 -1.3 -0.4 -1.6 0.3 -0.4 2.5 1.3
Type 2 Diabetes (T2D) (2018) 0.3 0.6 2.5 0.1 -0.8 -1.0 -0.1 0.1 0.2 -1.3 -0.6 -0.1 0.0 -1.6 1.0 -0.1 -1.2
Lung FEV1/FVC ratio 0.3 1.7 4.2 -1.8 -1.5 -1.8 -0.1 0.3 1.5 -2.1 0.2 1.7 0.4 -1.5 0.2 1.0 -1.1
Lung FVC 0.2 1.2 5.2 1.7 0.6 0.9 -0.4 -0.6 -0.6 1.4 -0.2 -2.3 -1.4 1.2 0.1 0.3 0.9
Neuroticism 0.7 1.6 4.9 1.4 -0.6 -0.9 -1.3 -0.9 0.6 1.1 -1.3 -0.7 -2.2 1.5 -1.7 1.3 1.1
Chronotype (morning person) 1.2 2.9 6.4 -2.3 1.9 1.6 2.2 1.6 -0.4 -1.6 0.3 1.4 1.3 -2.0 1.5 -1.3 -2.5
Hair Pigment 0.2 6.6 17.6 0.9 -3.3 -3.6 -2.9 -2.3 4.2 1.6 -3.2 -2.6 -2.5 0.0 -0.8 2.3 2.3
Tanning 0.1 0.8 1.9 -1.3 1.1 1.4 1.1 1.3 0.4 -0.2 0.5 0.3 0.7 -0.6 -0.8 -1.0 -0.8
Hand grip strength (left) 0.7 1.8 7.9 -0.1 1.2 1.8 0.9 0.2 -0.8 0.2 2.3 0.4 2.0 -0.2 0.9 -2.8 0.1
Number of treatments/medications taken 0.5 1.0 3.9 -0.6 -0.2 -0.9 -0.2 -0.7 0.8 -1.1 -0.4 0.8 -2.0 -1.7 0.6 0.9 -1.1
Average weekly spirits intake 0.5 0.6 1.6 -0.9 0.6 0.2 0.8 0.7 0.7 -1.1 0.6 0.9 -0.4 -1.3 0.4 -0.1 -1.1
Sensitivity / hurt feelings 1.5 2.6 12.1 0.1 -0.7 -1.4 -0.3 1.3 2.8 -0.5 -2.2 -0.3 -2.5 0.3 -3.5 1.0 0.5
Frequency of depressed mood in last 2 weeks 1.0 1.4 3.8 0.6 -0.5 -1.1 -1.4 -1.0 0.1 1.5 -0.8 -0.4 -1.9 0.7 -1.2 1.4 1.8
Hearing difficulty/problems: Yes 0.9 1.4 5.9 0.2 0.3 1.4 0.0 0.2 -0.9 2.0 -1.1 0.6 1.4 2.4 -0.8 0.0 1.2
Relative age of first facial hair 0.3 0.7 2.3 0.3 0.7 1.5 0.4 0.9 -0.1 0.8 1.3 -0.1 0.6 1.1 -0.7 -0.5 0.7
Other serious medical condition/disability diagnosed by doctor 0.6 0.7 2.5 0.5 -0.9 -1.1 -1.2 -1.6 -0.6 0.1 0.5 -0.5 -0.6 -0.3 -0.4 1.3 0.9
Ever used hormone-replacement therapy (HRT) 0.2 0.3 1.6 0.7 0.3 0.3 -0.0 -0.5 -1.1 0.1 0.3 0.2 -0.1 0.1 -1.3 0.1 0.1
Ever had hysterectomy (womb removed) 0.4 0.4 1.2 0.4 0.7 1.1 0.5 -0.2 -1.0 0.5 1.0 0.5 1.0 -0.2 -0.1 -0.5 0.1
Systolic blood pressure, automated reading 0.2 0.7 2.6 -0.2 0.4 0.5 0.7 0.4 -0.3 -1.2 -0.1 1.6 -0.3 -0.9 1.2 -0.5 -1.1
Eye problems/disorders: Diabetes related eye disease 0.2 0.2 1.0 0.0 -0.1 0.1 0.2 -0.0 0.7 -0.2 -0.1 0.2 0.1 -1.0 0.3 -0.8 -0.3
Angina 1.0 1.3 2.9 -0.5 1.6 1.2 1.7 1.6 -0.7 -0.9 1.4 0.5 0.2 -1.1 -0.2 -1.2 -1.7
Medication for hormone replacement therapy 0.4 0.4 1.4 -0.9 -0.4 -0.5 0.1 0.3 0.5 -0.5 0.6 1.2 -0.4 -0.1 -0.7 1.1 -0.3
Vitamin and mineral supplements 1.9 2.6 7.0 -0.9 2.1 2.0 2.3 1.9 -1.1 0.3 2.6 0.3 1.7 -1.4 -1.0 -1.7 -1.0
Supplements: Zinc 0.5 0.5 2.1 -1.3 -0.3 -0.5 -0.0 0.9 -0.4 -1.4 0.9 0.9 0.4 -0.1 -0.4 0.1 -0.5
Medication: Co-codamol 0.2 0.3 1.6 -0.5 -0.1 -0.2 0.1 0.1 0.1 -0.6 1.0 0.5 0.2 -1.3 -0.2 0.1 -0.3
Medication: Metformin 0.4 0.6 3.0 0.2 0.3 0.2 0.3 -0.4 -1.7 -0.4 1.0 0.0 1.0 -0.8 1.2 -0.3 -0.6
Diabetes (father) 1.1 1.4 7.2 -1.1 -1.1 -1.3 -0.1 0.9 2.7 -0.4 -0.4 -0.3 0.8 -0.9 -2.1 0.8 0.3
Diabetes (mother) 0.8 1.1 2.6 1.4 -1.2 -0.9 -1.6 -1.5 0.5 0.6 -0.9 -0.5 -0.9 0.5 -0.1 1.0 1.5
Severe depression (siblings) 1.4 1.5 5.4 0.5 -1.2 -1.8 -1.4 -1.3 1.0 -0.4 -1.2 -0.2 -2.3 0.4 -0.6 2.0 0.6
Pack years adult smoking proportion 0.7 1.0 3.9 0.3 -0.4 -1.0 -0.7 -0.8 2.0 0.2 -0.9 -0.8 -1.5 -1.2 -1.0 0.8 0.7
Impedance of leg (right) 0.2 0.9 4.2 0.7 -1.2 -0.7 -1.1 -0.8 -0.9 0.4 -0.2 -0.1 1.0 2.0 -0.4 1.1 1.0
Leg fat-free mass (left) 1.4 7.4 14.4 -3.2 2.3 2.2 3.4 2.9 0.8 -2.8 2.6 2.4 1.8 -3.4 2.0 -3.1 -3.8
Trunk fat percentage 2.4 9.6 23.9 -3.2 0.7 1.2 2.5 2.0 -1.9 -4.9 2.8 3.9 3.3 -3.1 4.0 -1.3 -4.9
Hand grip strength (right) 1.5 4.0 14.3 -0.9 2.0 2.6 2.2 1.6 -0.8 -0.5 2.5 1.6 3.1 -0.9 1.3 -3.8 -1.1
Townsend deprivation index at recruitment 1.1 1.5 6.7 1.4 -1.1 -1.7 -1.2 -1.7 -1.6 -0.3 -0.3 -0.2 -0.8 0.7 -0.5 2.6 0.5
Current tobacco smoking 0.2 0.3 1.7 0.3 -0.0 -0.5 -0.4 -0.4 1.3 0.1 -0.8 -0.2 -0.7 -0.8 0.1 0.3 0.5
Average weekly fortified wine intake 0.6 0.7 3.1 -0.8 -0.6 -0.0 0.4 0.7 0.1 -1.2 1.1 1.0 1.8 -0.6 -0.3 -0.4 -0.7
Maternal smoking around birth 0.5 0.8 3.2 0.3 1.3 0.4 0.8 0.6 -1.8 -0.6 1.1 -0.3 -0.9 -0.6 -0.9 0.6 -0.8
Fed-up feelings 0.7 1.3 4.6 -0.3 -1.1 -2.1 -0.8 -0.3 0.8 -0.8 0.1 0.6 -1.8 -1.2 -0.8 2.0 -0.1
Frequency of unenthusiasm / disinterest in last 2 weeks 1.1 1.4 3.0 1.3 -1.0 -1.6 -1.3 -1.5 1.0 0.9 -1.2 -0.6 -1.0 0.1 -1.1 1.7 1.5
Relative age voice broke 1.2 1.9 9.1 0.7 2.0 3.0 1.4 1.1 0.2 1.2 1.9 -0.3 0.1 0.7 0.4 -1.9 -0.1
Taking other prescription medications 0.9 1.3 4.8 -1.3 1.1 0.5 1.3 0.9 0.9 -1.1 0.5 1.4 -0.2 -2.2 0.7 -0.6 -1.8
Age when periods started (menarche) 0.9 2.2 8.3 -2.9 0.9 0.6 0.9 0.1 1.3 -0.3 1.4 1.8 2.8 -0.9 1.2 -1.8 -0.7
Bilateral oophorectomy (both ovaries removed) 1.3 1.5 3.3 -1.2 0.2 0.0 1.4 1.2 -0.3 -1.4 1.6 1.6 1.8 -1.6 -0.5 -0.4 -1.6
Heel bone mineral density (BMD) T-score, automated (left) 0.5 1.2 4.5 1.3 -1.2 -1.2 -0.9 -0.6 -1.3 0.4 -2.1 -1.2 -0.6 0.9 0.1 1.2 0.4
Tinnitus: Yes, but not now, but have in the past 3.3 3.5 9.1 -2.8 1.3 0.5 1.9 3.0 0.8 -1.9 1.6 2.4 0.2 -2.2 -2.4 -0.6 -1.8
Qualifications: CSEs or equivalent 1.9 2.4 6.8 -1.9 -0.1 0.2 1.3 2.1 1.7 -2.6 -0.3 2.2 1.7 -1.2 -0.0 -1.1 -2.0
Serious illness, injury or assault to yourself 0.5 0.6 1.5 -0.7 -0.8 -0.5 0.2 -0.5 0.3 -1.2 0.4 1.2 1.2 -0.5 1.1 0.6 -0.7
High blood pressure 0.4 1.0 4.8 0.2 -0.1 -0.9 -0.4 -0.9 1.0 -0.0 -1.6 -0.7 -2.2 -1.6 0.8 0.1 -0.8
Hayfever, allergic rhinitis or eczema 0.8 1.6 6.3 0.1 -1.3 -1.5 -1.1 -1.4 -0.7 0.5 -0.5 0.4 -1.1 0.6 -2.2 2.5 1.5
Multivitamins +/- minerals 3.3 4.2 8.8 1.3 -2.9 -2.9 -3.0 -1.9 1.8 -0.2 -2.9 -0.6 -2.3 1.6 0.7 2.4 1.4
Stomach or abdominal pain in last month 1.0 1.2 3.2 -1.0 -0.6 -1.2 0.5 1.7 1.3 -1.8 -0.7 0.4 -0.9 -1.2 -0.2 0.3 -1.6
Supplements: Glucosamine 0.6 0.7 3.9 1.3 0.3 0.3 -0.6 -0.5 0.8 0.3 -0.4 -1.1 -2.0 1.2 0.6 -0.2 0.3
Diverticular disease/diverticulitis (self-reported) 0.9 1.1 6.9 1.0 0.2 0.8 -0.3 -0.4 -2.6 0.4 0.8 0.6 0.4 2.3 -0.0 0.3 0.4
Medication: Atenolol 0.6 0.7 5.8 0.1 -0.2 -0.7 -0.3 0.2 1.0 0.3 -0.8 0.3 -2.4 -0.1 -1.1 0.6 0.4
Medication: Levothyroxine sodium 0.6 1.1 4.3 0.4 -1.3 -1.4 -1.0 -0.3 -1.1 -0.2 -0.8 -0.2 -0.6 0.4 -2.1 1.7 0.5
Sitting height 1.0 6.8 14.5 -3.8 2.0 1.6 3.1 3.0 0.2 -2.5 2.2 3.3 2.9 -3.5 -0.3 -2.0 -2.9
Chronic bronchitis/emphysema (father) 0.9 1.0 5.9 0.6 -0.8 -1.4 -0.9 -0.5 -0.5 -1.5 -2.4 -0.3 -0.1 -0.9 0.1 0.7 -0.4
High blood pressure (mother) 1.7 2.3 8.1 0.3 -2.5 -2.5 -1.7 -0.9 2.9 -0.9 -1.5 0.2 -0.6 -0.4 0.6 2.0 0.6
Body mass index (BMI) 0.8 3.4 8.8 -1.6 0.5 0.4 1.4 0.5 -0.8 -2.9 1.7 1.9 0.8 -2.9 3.0 -0.7 -2.9
Impedance of leg (left) 0.2 0.8 3.4 0.3 -1.1 -0.4 -0.8 -0.4 -1.2 -0.2 -0.1 0.5 1.8 1.6 -0.1 0.8 0.5
Leg predicted mass (left) 1.3 6.9 13.5 -3.1 2.2 2.1 3.2 2.8 0.8 -2.7 2.5 2.3 1.7 -3.3 1.9 -3.0 -3.7
Trunk fat mass 2.4 10.2 25.4 -3.5 1.3 1.6 2.9 2.3 -0.9 -4.8 2.9 3.7 3.0 -3.6 4.0 -2.0 -5.0
Waist circumference 1.2 4.3 10.6 -2.2 1.2 0.9 1.9 1.0 -0.4 -2.9 1.8 2.2 1.0 -3.1 3.0 -1.2 -3.3
Number of incorrect matches in round 0.9 1.6 8.1 -0.2 1.7 1.8 0.7 -0.5 -0.7 1.1 1.6 0.0 -0.2 -0.1 2.9 -1.6 -0.0
Past tobacco smoking 0.4 0.8 2.7 -0.0 0.8 1.6 1.0 0.6 0.5 0.8 0.9 0.7 1.2 0.2 0.6 -1.7 0.0
Alcohol usually taken with meals 2.3 3.7 8.5 -1.6 2.3 2.3 2.9 2.7 -0.1 -1.0 1.6 1.6 1.7 -1.5 -1.1 -2.6 -2.1
Nervous feelings 0.9 1.6 4.0 1.8 -0.8 -1.4 -1.4 -1.5 -0.1 0.9 -0.5 -0.4 -1.1 1.1 -2.0 1.6 1.6
Frequency of tenseness / restlessness in last 2 weeks 1.1 1.8 6.0 2.5 0.1 -0.4 -0.9 -2.0 -1.6 2.1 -0.1 -0.3 -0.9 1.2 -0.7 0.8 1.7
Hearing difficulty/problems with background noise 0.7 1.2 5.4 -0.0 0.3 1.1 -0.5 -1.0 -1.0 1.6 -0.5 0.7 0.9 2.3 -1.1 0.2 1.4
Hair/balding pattern: Pattern 2 1.7 2.2 8.6 -1.9 0.4 0.1 1.6 1.9 1.0 -1.5 0.8 2.9 0.1 -1.7 -1.6 -0.1 -1.7
Had menopause 0.5 0.6 3.9 2.0 -0.4 0.4 -0.6 -0.8 -0.4 0.8 -0.5 -0.7 -0.4 0.9 0.1 -0.0 0.6
Had other major operations 1.1 1.3 3.3 1.0 -1.8 -1.1 -1.7 -1.4 -1.1 0.4 -1.3 -0.6 0.8 0.9 0.8 0.8 1.4
Forced vital capacity (FVC) 0.6 2.5 7.2 -0.8 1.8 2.7 2.0 2.2 -0.9 -0.4 1.3 0.7 1.7 0.1 1.1 -2.3 -1.4
Heel bone mineral density (BMD) T-score, automated (right) 0.7 1.7 4.4 1.4 -1.4 -1.3 -1.5 -1.1 -1.9 1.0 -2.1 -0.8 -0.1 1.1 -0.2 1.4 1.4
Ever unenthusiastic/disinterested for a whole week 0.6 0.7 2.1 0.6 1.5 1.1 0.7 -0.2 -0.1 1.2 0.4 -0.6 -0.9 -1.4 -1.1 -0.0 0.1
Qualifications: None of the above 0.8 1.7 6.1 -0.9 -1.6 -1.6 -0.6 -0.1 1.0 -2.5 -0.5 1.1 0.6 -1.4 1.0 1.9 -1.4
Financial difficulties in last 2 years 0.3 0.4 2.3 -1.5 -0.7 -0.7 -0.3 0.6 0.6 -0.1 0.3 -0.2 -0.1 0.4 -1.1 0.4 0.2
Mouth/teeth dental problems 1.6 2.5 5.9 -2.2 1.4 1.6 1.7 0.9 0.9 -0.8 2.4 0.9 0.5 -1.2 2.4 -2.2 -1.4
Heart attack 2.8 3.6 6.9 -2.6 2.0 1.6 2.5 2.3 0.3 -1.8 2.4 1.7 0.9 -2.4 -0.2 -0.8 -2.5
Allergy 1.8 4.2 13.8 -1.8 2.5 2.8 2.5 3.0 1.2 -0.7 1.1 0.3 1.3 -0.9 1.4 -3.7 -2.2
Pain all over the body in last month 0.2 0.3 1.2 0.7 0.4 0.5 0.4 -0.1 -0.7 -0.2 -0.2 0.3 1.1 -0.4 -0.7 -0.1 -0.2
Diabetes (self-reported) 0.5 0.7 2.5 0.6 -1.2 -1.6 -1.0 -0.9 -1.1 -0.6 -0.8 0.2 -0.3 -0.4 0.3 1.1 -0.1
Hayfever/allergic rhinitis (self-reported) 0.5 0.7 3.1 -0.4 -0.5 -1.0 -0.4 0.4 0.5 -0.2 -0.2 0.8 -1.3 -0.2 -1.8 1.3 0.9
Medication: Ramipril 0.3 0.4 1.8 -0.7 0.6 -0.1 0.5 0.3 0.8 -0.6 -0.0 0.2 -0.9 -1.0 0.2 -0.3 -1.3
Medication: Simvastatin 1.1 1.6 2.7 -1.3 1.3 1.3 1.5 0.7 -1.2 -1.1 1.1 1.2 1.5 -1.5 0.6 -1.3 -1.6
Fluid intelligence score 1.2 2.4 7.5 1.0 2.0 2.2 0.6 -0.1 -1.1 2.7 0.1 -0.8 -0.6 2.4 -1.7 -1.9 1.4
Illnesses of siblings 0.5 0.8 2.2 -0.6 0.7 1.1 1.0 0.7 1.0 0.1 0.6 -0.6 1.0 -0.2 1.2 -1.5 -0.9
Neuroticism score 1.1 2.2 5.2 1.8 -1.1 -1.8 -1.5 -1.2 0.8 1.0 -1.4 -0.7 -2.3 1.0 -2.1 1.8 1.4
Weight 1.8 8.7 18.8 -3.3 1.8 2.0 3.1 2.4 -0.4 -3.7 2.9 3.1 2.6 -3.7 3.3 -2.7 -4.3
Impedance of arm (right) 0.4 1.9 7.3 -1.7 -0.3 0.7 0.6 1.9 -1.8 -1.2 0.1 1.9 2.7 0.9 -1.0 0.3 -1.1
Arm fat percentage (right) 1.9 7.4 19.4 -3.0 0.9 0.8 2.3 1.8 -1.5 -4.4 2.2 3.6 2.1 -3.6 2.8 -0.9 -4.4
Trunk fat-free mass 0.7 3.8 9.4 -1.9 2.2 1.9 2.4 1.8 2.2 -1.2 1.6 0.8 0.2 -2.6 1.4 -3.1 -2.0
Hip circumference 2.1 8.9 17.8 -3.0 2.2 2.1 3.3 2.4 -1.6 -3.6 3.2 3.9 2.4 -3.8 2.7 -2.2 -4.2
Time employed in main current job 1.4 1.6 4.3 2.1 -1.0 -1.2 -0.9 -0.7 0.5 0.7 -1.2 -0.3 -1.8 0.3 -1.7 1.8 1.3
Alcohol intake versus 10 years previously 1.0 1.5 5.9 -1.1 -0.6 -1.2 0.5 1.0 0.3 -1.5 0.5 1.1 2.0 -2.4 -0.8 0.5 -1.4
Father’s age at death 0.8 1.1 8.9 -0.5 -0.4 -0.3 -0.4 -0.1 3.0 -0.9 -0.6 -0.8 0.0 -0.1 2.0 -0.4 -0.4
Worrier / anxious feelings 0.8 1.4 8.5 0.8 -0.3 -1.0 -0.6 0.1 2.1 -0.2 -2.0 -0.7 -2.9 -0.3 -0.3 0.4 0.1
Frequency of tiredness / lethargy in last 2 weeks 1.1 1.8 8.1 0.7 -1.4 -2.2 -1.6 -1.5 -0.6 -0.3 -0.5 0.3 -1.3 0.8 -0.4 2.8 0.9
Falls in the last year 0.5 0.6 2.6 0.1 -1.6 -0.9 -1.0 -0.5 0.1 -0.3 -0.0 0.2 -0.3 0.7 1.6 0.9 0.4
Hair/balding pattern: Pattern 3 0.1 0.2 0.9 0.3 0.5 0.4 0.5 -0.0 -0.2 -0.8 -0.1 0.1 0.1 -0.6 0.2 0.4 -1.0
Number of live births 0.4 0.6 2.3 1.2 0.3 0.0 -0.2 -1.1 -1.0 1.5 -0.2 -0.6 0.1 -0.1 -0.9 0.3 1.1
Forced expiratory volume in 1-second (FEV1) 0.5 1.6 4.3 -0.5 0.5 1.8 1.3 1.7 -0.9 -0.7 1.2 0.8 2.1 0.5 1.4 -1.6 -1.3
Pulse rate 0.4 0.8 3.5 0.9 -0.9 -0.7 -0.4 -0.8 -1.7 -0.5 0.4 0.7 1.9 0.3 -0.1 0.6 0.3
Happiness 0.5 0.6 4.4 0.6 -0.2 0.0 0.1 0.2 -2.1 -0.4 -0.1 0.9 1.3 0.4 -0.5 0.1 -0.5
Noisy workplace 0.4 0.5 1.3 -1.1 -0.6 -1.0 -0.1 0.1 0.0 -1.1 0.1 1.1 -0.2 -0.6 0.3 0.9 -0.9
Qualifications: A levels/AS levels or equivalent 0.9 2.1 7.7 1.4 1.0 1.1 -0.2 0.6 -1.0 2.8 -0.3 -2.1 -0.6 1.7 -1.4 -1.2 2.1
Serious illness, injury or assault of a close relative in last 2 years 0.9 1.0 1.7 1.2 -0.7 -1.1 -1.0 -1.2 0.6 0.8 -1.3 0.7 -0.9 1.2 -0.7 1.1 0.9
Mouth/teeth dental problems: Dentures 0.9 1.5 5.0 2.2 -1.5 -1.2 -1.4 -1.0 0.4 1.0 -1.9 -0.9 -0.1 0.3 -0.5 1.4 1.1
Asthma 2.0 3.9 10.6 2.4 -1.9 -2.4 -2.5 -3.3 -1.8 0.9 -1.1 -0.9 -1.5 1.1 -0.1 3.0 2.1
Medication: Ibuprofen (e.g. Nurofen) 0.5 0.7 1.7 0.9 -0.9 -1.0 -1.0 -1.2 -0.4 0.3 -0.7 -0.1 -1.0 1.3 -0.1 0.8 0.6
Medication: Cholesterol lowering 1.6 2.5 4.0 -1.9 1.5 1.2 1.7 1.0 -1.1 -1.2 1.6 1.0 1.8 -1.9 2.0 -1.8 -2.0
Depression (self-reported) 0.6 0.7 2.2 -0.7 0.3 -0.3 0.8 1.5 0.1 -0.9 -0.1 0.4 1.4 -1.1 -1.2 -0.4 -0.7
Medication: Lansoprazole 1.0 1.2 3.4 0.5 -1.7 -1.9 -1.3 -0.9 -0.2 -1.2 -1.3 -0.7 -0.4 -0.1 1.6 1.0 -0.4
Prospective memory result 0.5 0.6 2.8 -1.1 -0.1 -0.6 0.1 0.1 1.7 -0.8 -0.3 0.5 -0.3 -1.5 0.5 0.4 -0.6
Lung cancer (father) 0.7 0.8 2.4 1.6 -0.6 -0.3 -0.8 -1.0 -0.5 1.4 -0.1 -1.1 -0.6 1.1 0.6 0.3 1.1
Illnesses of mother 0.5 0.7 3.8 -0.2 1.0 0.7 0.8 0.7 -1.9 0.7 0.2 -0.5 0.4 -0.3 -0.2 -1.2 -0.3
Forced expiratory volume in 1-second (FEV1), Best measure 0.6 2.0 4.5 -1.1 0.5 1.6 1.7 2.1 -0.2 -1.6 1.6 1.2 1.7 -0.2 1.4 -1.5 -2.0
Pulse wave Arterial Stiffness index 1.4 1.6 5.4 -1.5 0.3 0.4 1.5 2.3 0.6 -1.4 0.7 1.3 0.9 -1.2 0.2 -0.8 -2.3
Impedance of arm (left) 0.5 2.4 12.4 -1.7 -0.4 0.7 0.8 1.9 -1.9 -1.6 0.5 2.0 3.5 0.8 -0.4 0.2 -1.4
Arm fat mass (right) 2.0 8.1 20.1 -3.1 1.5 1.4 2.8 2.1 -0.6 -4.1 2.6 3.2 2.1 -3.9 3.2 -1.9 -4.5
Trunk predicted mass 0.7 3.8 9.1 -2.0 2.2 1.8 2.4 1.8 2.2 -1.3 1.6 0.9 0.2 -2.7 1.3 -3.0 -2.1
Standing height 1.0 10.3 18.3 -4.0 2.7 3.5 3.9 4.3 1.4 -2.4 2.5 2.8 3.8 -2.4 1.0 -4.3 -3.6
Length of working week for main job 0.5 0.6 1.5 -0.9 0.3 0.1 0.6 0.6 0.6 -0.8 1.2 0.4 0.0 -0.7 1.1 -1.0 -1.0
Exposure to tobacco smoke at home 0.3 0.3 1.4 0.4 -0.7 -1.2 -0.6 -0.4 0.2 -0.7 -0.4 0.2 -0.6 -0.2 -0.2 1.0 0.1
Breastfed as a baby 0.4 0.5 4.4 0.0 0.2 0.4 0.3 0.2 2.1 0.0 -0.4 -0.1 0.6 -0.9 0.3 -1.1 -0.4
Tense / ‘highly strung’ 2.5 4.1 11.9 2.0 -0.1 -1.1 -1.8 -2.2 -1.4 1.9 -1.5 -1.4 -2.4 1.9 -3.5 2.8 2.3
Seen doctor (GP) for nerves, anxiety, tension or depression 0.4 0.7 3.1 -0.6 -0.1 0.2 0.5 0.7 0.0 -0.3 1.7 1.8 1.4 0.2 -0.6 -0.3 -0.0
Hair/balding pattern: Pattern 4 0.3 0.7 3.0 0.1 0.4 1.0 -0.3 -0.4 -1.1 1.7 0.1 -0.3 0.9 0.3 0.4 -1.2 1.1
Birth weight of first child 0.4 0.7 2.8 0.0 -0.3 1.7 0.1 1.0 -0.2 0.0 -0.4 0.2 1.6 0.8 1.2 -1.0 -0.2
Peak expiratory flow (PEF) 0.6 1.4 5.9 -0.6 -0.9 0.1 0.3 1.0 -1.2 -1.6 0.7 1.2 2.0 -0.0 2.4 -0.8 -1.1
Pulse wave reflection index 0.2 0.2 1.2 -0.3 -1.1 -0.6 -0.2 0.5 0.1 0.1 -0.4 0.1 -0.5 0.4 0.5 0.4 -0.2
Ever highly irritable/argumentative for 2 days 0.2 0.3 1.3 -0.4 0.3 -0.3 -0.1 0.2 -1.1 0.4 -0.8 0.3 -0.1 0.0 -0.7 0.8 0.1
Loud music exposure frequency 1.0 1.1 4.4 1.3 0.2 0.7 -0.1 0.2 -1.4 1.7 -0.7 0.2 0.6 2.1 -1.4 -0.2 1.1
Qualifications: O levels/GCSEs or equivalent 0.6 0.9 4.0 -0.1 0.8 0.4 -0.1 0.5 0.4 1.1 -1.0 -0.9 -1.4 1.2 -2.0 -0.8 0.8
Mouth/teeth dental problems: Bleeding gums 0.9 1.2 3.3 0.6 -0.6 -1.2 -1.1 -0.5 -0.7 0.9 -0.5 -0.8 -1.3 0.5 -1.8 1.8 1.3
Blood clot in the leg (DVT) 0.7 0.9 2.3 1.3 -0.3 -0.0 -0.9 -1.1 -0.4 1.3 -0.7 -1.0 -0.4 1.5 0.0 0.7 1.4
Medication: Paracetamol 1.0 1.7 3.4 1.8 -1.8 -1.6 -1.7 -1.7 0.1 0.4 -1.1 0.2 -1.3 1.3 -0.1 1.6 1.3
Headache pain in last month 3.1 5.3 14.8 1.2 -3.1 -3.9 -2.4 -1.0 1.1 -0.5 -3.6 -0.9 -2.4 1.0 -2.9 3.4 0.9
Medication for cholesterol, blood pressure or diabetes 0.3 0.5 3.9 0.6 -0.6 -0.2 -0.3 0.4 0.4 0.1 -0.3 -0.5 0.1 0.8 -2.0 0.5 1.0
Glaucoma (self-reported) 1.3 1.5 5.4 -0.0 1.6 2.3 1.5 0.8 -0.8 0.9 1.7 0.1 1.6 0.1 0.3 -1.7 -0.2
Gout (self-reported) 0.9 1.2 4.0 -1.1 1.1 0.2 1.5 1.2 0.4 -0.8 0.7 1.2 0.3 -1.6 -2.0 0.4 -1.3
Hypothyroidism/myxoedema (self-reported) 0.8 1.5 5.8 0.3 -1.2 -1.5 -1.2 -0.8 -1.0 0.2 -1.6 -0.4 -1.1 0.4 -2.4 1.8 0.8
Medication: Amlodipine 1.0 1.5 4.5 0.6 -1.3 -1.1 -1.6 -1.2 -0.4 0.8 -2.1 -0.2 -1.0 1.7 -0.6 1.4 1.2
Medication: Ventolin 100micrograms inhaler 0.5 0.6 2.6 -0.8 0.3 -0.4 0.2 -0.5 -1.6 0.2 0.3 1.1 0.3 -0.4 -1.3 1.2 0.2
Birth weight 0.8 1.7 6.0 -1.1 0.7 1.1 1.3 1.8 -0.1 -2.4 0.7 1.1 1.6 -0.9 0.0 -1.4 -1.9
Chronic bronchitis/emphysema (mother) 1.0 1.2 3.4 0.5 -0.1 -0.3 -0.9 -1.6 1.1 1.9 -0.9 -1.2 -1.8 0.2 -0.8 0.6 1.3
High blood pressure (siblings) 1.0 1.5 3.9 0.9 -1.9 -1.8 -1.7 -1.0 -0.4 0.1 -1.7 0.3 -0.4 0.8 -0.6 2.0 1.1
Forced vital capacity (FVC), Best measure 1.0 3.5 7.2 -1.5 2.0 2.7 2.5 2.7 -0.2 -1.1 1.8 1.1 1.7 -0.7 1.2 -2.6 -2.2
Body fat percentage 2.1 8.4 22.1 -3.0 0.6 0.9 2.1 1.5 -1.8 -4.7 2.6 3.7 3.0 -3.1 3.9 -1.0 -4.6
Leg fat percentage (right) 1.0 3.5 10.2 -1.6 0.1 0.1 1.1 0.4 -1.3 -3.2 1.8 2.5 1.4 -2.2 3.0 -0.4 -2.9
Arm fat-free mass (right) 0.7 3.8 7.7 -1.7 1.6 1.5 2.2 1.6 1.5 -1.9 1.9 1.2 0.8 -2.8 2.2 -2.8 -2.5
Exposure to tobacco smoke outside home 1.0 1.3 5.9 1.1 -1.4 -1.9 -1.2 -0.8 0.0 -0.4 -1.4 -0.3 -2.4 0.6 -0.3 1.2 -0.0
Comparative body size at age 10 1.2 3.4 8.6 -0.8 1.2 1.2 2.0 1.3 2.5 -1.6 0.9 0.8 0.6 -2.2 2.7 -2.9 -2.5
Number of full brothers 0.4 0.5 2.2 -0.8 -0.3 -0.3 0.4 1.4 0.1 -1.5 -0.2 0.5 0.4 -0.0 0.1 0.1 -0.9
Worry too long after embarrassment 0.4 0.7 2.5 1.0 0.4 0.4 -0.2 -0.6 0.2 1.2 0.0 -1.2 -1.1 1.6 -1.0 -0.2 0.8
Seen a psychiatrist for nerves, anxiety, tension or depression 0.6 0.8 2.8 -1.1 0.5 0.3 1.0 1.0 0.5 -0.4 1.7 1.2 1.3 -0.8 -0.8 -0.1 -0.3
Wheeze or whistling in the chest in last year 0.6 1.1 2.4 -0.6 -0.6 -1.4 -0.5 -1.5 0.1 -1.3 0.3 1.3 -0.3 -1.6 1.5 1.5 -0.5
Number of children fathered 0.4 0.4 0.9 -0.8 -0.1 -0.5 0.0 0.9 0.7 -1.0 -0.3 -0.8 -0.9 -0.5 -0.6 0.2 -0.7
Reason for reducing amount of alcohol drunk: Health precaution 3.0 3.5 7.3 -1.7 2.0 2.6 2.2 2.7 -0.8 -0.5 2.7 1.6 1.5 -1.0 1.1 -2.5 -1.3
Age at first live birth 1.4 2.6 8.0 -1.1 2.0 2.8 1.7 1.8 -1.4 1.0 2.1 -0.0 1.6 0.8 0.5 -2.4 -0.3
Pulse wave peak to peak time 1.0 1.1 4.1 1.2 -0.1 -0.2 -1.3 -2.0 -0.8 1.1 -0.3 -1.2 -0.6 1.0 -0.0 0.6 1.9
Health satisfaction 1.1 1.5 10.7 1.4 0.8 1.0 0.1 -0.6 -3.3 1.0 1.9 0.1 -0.0 0.7 -0.4 0.7 0.4
Shortness of breath walking on level ground 0.4 0.5 3.0 -0.1 0.4 0.6 0.3 0.3 -1.3 0.5 1.7 0.5 0.5 -0.1 0.4 0.1 0.2
Qualifications: College or University degree 0.6 2.0 7.9 1.0 1.0 2.0 0.5 0.4 -2.3 2.0 1.4 -0.2 0.5 2.8 -0.3 -1.2 1.0
Eye problems/disorders: None of the above 0.3 0.4 1.1 0.9 -0.0 -0.2 -0.3 -0.0 -0.4 0.5 -0.0 -0.8 -0.7 1.0 -0.8 0.7 0.5
Mouth/teeth dental problems: Loose teeth 0.2 0.3 0.8 -0.3 -0.1 -0.7 -0.3 -0.3 -0.6 -0.2 -0.9 0.8 0.0 -0.6 -0.8 0.4 0.1
Emphysema/chronic bronchitis 0.5 0.6 3.6 -0.1 -0.6 -0.8 0.1 -0.1 0.5 -1.1 0.1 1.9 0.2 -0.8 0.0 0.5 -0.9
Medication for pain relief, constipation, heartburn 1.0 1.8 6.2 -0.6 1.5 2.5 1.4 1.7 -0.2 1.0 1.2 -0.1 2.2 -0.0 0.3 -2.0 0.0
Neck or shoulder pain in last month 2.3 3.2 8.3 1.3 -1.9 -2.6 -2.1 -1.1 0.3 -0.5 -2.7 -0.6 -2.8 0.9 -1.1 2.9 0.8
Medication: Blood pressure 0.4 0.6 2.9 -0.6 0.8 0.2 0.1 -0.6 1.0 0.2 -0.1 0.2 -1.4 -0.9 1.7 -0.2 -0.7
Angina (self-reported) 1.1 1.5 3.6 -0.5 1.7 1.2 1.8 1.7 -0.3 -0.9 1.5 0.4 -0.0 -1.2 0.1 -1.3 -1.9
Migraine (self-reported) 0.5 0.6 1.7 0.7 -1.3 -0.8 0.1 0.8 0.8 -1.2 -1.0 -0.2 1.0 0.2 0.7 -0.3 -1.0
Medication: Ibuprofen 0.1 0.2 0.8 0.5 0.0 0.0 -0.2 -0.5 -0.5 0.3 -0.1 0.1 -0.9 0.8 -0.3 0.2 0.3
Medication: Allopurinol 2.1 2.8 6.4 -2.2 1.3 0.2 1.9 2.1 1.5 -1.2 0.5 2.2 -0.4 -2.5 -2.4 0.4 -1.7
Medication: Omeprazole 1.1 1.3 3.7 1.4 -1.4 -1.5 -1.4 -0.8 0.5 0.2 -1.9 -0.9 -1.0 0.8 0.1 1.4 0.8
Medication: Seretide 50 evohaler 1.0 1.1 7.7 0.6 -0.4 0.3 -0.0 -0.5 -2.8 0.8 1.6 0.3 1.4 1.0 0.7 0.4 0.6
Mean time to correctly identify matches 1.1 2.1 8.9 1.0 2.1 1.6 0.5 -0.6 1.2 3.0 -0.3 -2.1 -1.8 0.2 -0.5 -1.0 1.3
Heart disease (mother) 0.5 0.6 3.0 -0.4 -0.4 0.1 0.5 1.3 0.5 -1.7 0.2 0.5 0.9 -0.6 0.2 -0.1 -1.1
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.7 0.9 2.8 -0.8 1.7 1.7 1.0 0.8 0.2 0.1 -0.3 0.8 -0.1 0.6 -0.5 -1.5 -0.5
Whole body fat mass 2.3 9.5 24.3 -3.3 1.2 1.4 2.7 2.0 -0.9 -4.7 2.8 3.6 2.7 -3.6 3.9 -1.8 -4.9
Leg fat mass (right) 1.4 5.4 13.4 -2.4 0.9 0.9 2.0 1.1 -0.3 -3.5 2.3 2.6 1.7 -3.0 3.4 -1.5 -3.7
Arm predicted mass (right) 0.9 4.6 9.2 -1.9 1.9 1.7 2.5 1.9 1.6 -2.1 2.2 1.4 1.1 -2.9 2.2 -3.0 -2.8
Pulse rate, automated reading 0.8 2.6 9.4 1.0 -2.3 -2.5 -2.4 -3.1 -1.1 -0.5 -0.9 0.2 0.3 0.1 0.6 2.1 1.4
Alcohol intake frequency. 1.7 3.9 12.6 -1.2 -1.3 -1.8 1.1 2.1 2.2 -3.5 0.4 2.2 2.0 -3.2 0.7 0.2 -2.4
Comparative height size at age 10 0.3 1.6 6.0 -1.9 -0.9 -0.5 0.3 0.7 0.6 -1.7 0.5 1.9 2.4 -1.5 -0.7 -0.1 -0.8
Number of full sisters 2.7 3.3 9.6 1.3 -2.9 -2.8 -2.3 -2.3 -1.6 -0.2 -1.1 0.1 0.0 1.6 -0.5 3.1 0.7
Suffer from ‘nerves’ 1.5 2.4 9.4 2.2 -0.1 -0.3 -1.0 -1.1 -0.1 3.1 -1.2 -1.4 -0.9 1.8 -1.7 0.9 2.6
Overall health rating 0.4 0.9 3.8 0.3 -0.4 -1.4 -0.4 -0.8 -0.3 -1.0 0.3 0.4 -1.4 -1.6 -0.2 1.9 -0.7
Chest pain or discomfort 0.9 1.3 4.3 0.5 0.1 -1.0 -0.8 -1.6 -0.5 1.1 -0.8 -0.0 -1.6 0.2 -2.1 2.0 0.8
Had major operations 0.8 1.0 6.4 -2.5 0.6 0.1 0.8 0.5 -0.3 -1.1 0.9 0.7 1.0 -0.9 0.6 -0.4 -1.1
Age at last live birth 0.8 1.2 3.0 -0.7 1.0 1.7 0.9 0.9 -1.4 1.2 1.4 0.4 1.1 1.3 -0.5 -1.4 0.1
Family relationship satisfaction 0.6 0.7 2.1 -1.1 0.5 -0.0 0.7 0.7 -1.0 -0.9 0.2 1.5 0.6 -1.1 -0.7 -0.2 -1.1
Leg pain on walking 0.6 0.8 3.1 -0.5 -0.9 -0.4 -0.0 1.0 0.4 -1.8 0.4 1.1 -0.6 -0.0 -0.9 1.6 -0.8
Qualifications: NVQ or HND or HNC or equivalent 0.7 0.8 3.9 0.4 0.3 -0.1 -0.5 -0.9 0.2 2.0 -0.7 -0.6 -0.8 1.1 -1.5 -0.1 1.3
Commuting to job workplace: Car/motor vehicle 0.3 0.3 1.2 -0.1 0.6 0.4 0.7 1.1 0.0 -0.2 0.7 0.8 -0.3 -0.5 -0.4 -0.3 -0.5
Illness, injury, bereavement, stress in last 2 years 0.5 0.6 2.1 0.7 1.1 1.2 0.5 0.6 -1.2 0.6 0.0 -0.6 0.5 -0.2 -0.4 -1.5 0.4
Medication: Aspirin 2.0 2.7 6.5 -2.3 1.6 1.0 2.0 1.6 1.0 -2.0 1.2 1.0 0.5 -2.5 0.4 -1.5 -2.3
Supplements: Vitamin C 0.5 0.6 3.1 -0.2 -0.6 -0.7 -0.4 -0.4 -0.6 -0.8 -1.7 1.4 0.6 -0.4 -0.3 0.5 -0.1
Knee pain experienced in last month 1.1 1.7 3.4 1.8 -1.8 -1.1 -1.6 -1.4 -1.4 0.1 -0.8 -1.3 -0.7 1.6 0.2 1.7 0.7
Hypertension (Self-reported) 0.3 0.8 3.6 0.1 0.6 -0.1 0.1 -0.7 0.5 0.3 -1.1 -0.3 -1.9 -1.8 0.6 -0.3 -0.9
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.4 0.4 1.7 0.1 -0.0 -0.6 0.1 -0.5 1.3 -0.6 -0.9 0.2 -0.5 -1.0 0.9 0.5 -0.8
Illnesses of father: Heart disease 1.5 2.1 6.6 -1.7 0.9 1.4 1.7 2.3 -0.1 -1.5 1.3 2.6 0.8 -0.8 -1.0 -0.6 -1.5
Illnesses of siblings: Diabetes 1.4 1.7 7.2 0.1 -2.4 -2.7 -1.5 -0.4 0.2 -1.6 -1.5 -0.1 -0.4 -0.9 -0.2 1.8 0.2
Smoking status: Previous 0.5 0.7 2.7 -0.8 -0.8 -1.3 -0.3 0.2 -0.7 -1.6 -0.3 0.3 0.1 -1.0 0.1 1.3 -0.9
Forced expiratory volume in 1-second (FEV1), predicted 2.0 4.2 15.4 -2.3 1.5 2.1 2.9 3.9 1.4 -1.5 1.3 1.3 1.4 -1.2 -0.4 -2.2 -2.6
Whole body fat-free mass 0.9 5.0 9.8 -2.4 2.2 2.0 2.8 2.2 1.6 -1.9 2.0 1.5 0.9 -3.0 1.7 -3.1 -2.8
Leg fat-free mass (right) 1.5 8.0 15.4 -3.3 2.2 2.3 3.5 3.2 0.8 -3.0 2.5 2.6 2.2 -3.5 1.9 -3.2 -3.9
Arm fat percentage (left) 1.9 7.7 19.5 -2.8 0.9 0.9 2.4 1.8 -1.6 -4.4 2.5 3.5 2.5 -3.5 3.1 -1.1 -4.4
Average weekly red wine intake 0.6 0.8 3.5 -0.5 1.2 1.6 1.0 0.9 0.7 0.6 0.2 -0.1 -0.6 0.3 0.4 -1.9 -0.6
Handedness (chirality/laterality): Left-handed 0.4 0.5 4.3 0.2 -0.3 -0.1 -0.3 -1.1 0.0 0.1 -0.6 -0.1 -0.3 -0.1 2.1 -0.9 0.0
Mood swings 1.6 2.8 10.1 0.8 -2.2 -3.2 -2.1 -2.0 -0.4 -0.3 -0.8 0.8 -1.6 -0.5 -0.8 3.2 0.8
Loneliness, isolation 0.7 1.0 3.6 1.8 -0.7 -0.8 -0.6 -0.1 0.4 0.3 -1.0 -0.5 -1.9 0.5 -1.1 1.6 0.3
Long-standing illness, disability or infirmity 0.4 0.6 4.0 -0.3 0.0 -0.3 -0.6 -1.0 0.1 -0.1 0.5 -0.6 -0.9 -0.9 2.0 0.3 -0.1
Ever had bowel cancer screening 0.3 0.4 1.9 0.4 0.9 0.7 0.2 0.3 0.2 0.4 -0.8 -0.7 -0.5 -0.3 0.3 -1.4 -0.4
Diabetes diagnosed by doctor 0.4 0.7 2.6 0.0 -1.2 -1.6 -0.9 -1.0 -0.7 -0.9 -0.3 0.4 -0.0 -1.2 0.3 0.9 -0.2
Ever had stillbirth, spontaneous miscarriage or termination 0.5 0.5 2.1 -0.1 0.2 0.5 -0.2 0.5 0.1 1.0 -0.0 -0.5 -0.6 1.2 -1.4 0.4 1.0
Friendships satisfaction 0.4 0.5 2.3 1.0 -0.7 -0.3 -0.6 -0.8 -1.5 0.4 0.3 -0.1 1.0 0.8 0.3 0.1 0.6
Qualifications: nursing, teaching 0.4 0.6 2.7 0.5 0.4 0.6 0.3 0.3 -0.2 1.5 0.3 -0.8 -0.1 0.7 -1.7 -0.6 0.6
Commuting to job workplace: Walk 0.4 0.4 1.3 -0.5 -0.0 -0.7 -0.4 -0.9 -0.8 -0.2 -0.8 -0.2 -0.2 -0.6 -1.0 1.1 0.1
Eye problems/disorders: Cataract 0.2 0.2 2.4 -0.1 -0.2 -0.3 -0.3 -0.1 0.1 -0.2 -1.5 0.4 -0.3 -0.1 0.5 0.1 -0.1
Mouth/teeth dental problems: Mouth ulcers 1.6 2.6 11.9 1.1 -0.9 -0.9 -1.4 -0.0 -1.2 0.9 -1.6 -0.9 -1.4 2.5 -3.5 1.6 1.7
Medication for cholesterol 0.7 1.1 4.4 1.0 0.6 1.0 -0.2 -0.3 0.2 1.5 0.2 -1.1 0.2 2.1 1.8 -1.0 1.0
Medication: Laxatives (e.g. Dulcolax, Senokot) 1.2 1.5 5.2 -1.4 -0.1 -1.1 0.2 -0.3 1.8 -2.0 0.2 0.5 -0.4 -2.3 1.2 -0.2 -1.7
Back pain experienced in last month 0.4 0.6 1.7 -1.3 0.8 0.6 1.0 0.7 1.3 -0.4 0.1 1.0 0.0 -0.8 -0.4 -0.5 -0.9
Mineral and other dietary supplements 0.9 1.3 4.2 -1.9 -0.1 -0.6 0.9 0.5 -0.5 -1.3 0.8 1.2 1.8 -2.1 -0.4 0.3 -1.0
Breast cancer (self-reported) 0.3 0.3 1.0 0.1 0.8 0.9 0.5 -0.1 0.4 0.6 1.0 0.4 0.5 0.2 0.5 -0.7 0.0
Asthma (self-reported) 1.8 3.6 9.3 2.2 -1.8 -2.3 -2.4 -3.0 -1.9 1.0 -1.2 -0.9 -1.3 0.9 -0.3 3.0 2.0
Osteoporosis (self-reported) 0.3 0.4 0.7 0.6 -0.8 -0.7 -0.8 -0.1 -0.1 0.4 -0.3 -0.8 -0.7 0.7 0.4 0.7 0.5
Osteoarthritis (self-reported) 0.5 0.6 2.2 0.3 -0.9 -0.4 -1.0 -1.5 -0.8 -0.3 0.7 -0.2 1.4 0.1 0.9 0.1 0.7
Medication: Aspirin 1.6 2.1 6.6 -2.0 1.5 0.7 1.7 0.9 0.6 -1.9 1.1 0.8 0.6 -2.6 0.4 -1.1 -2.1
Medication: Gliclazide 1.0 1.2 4.2 -0.6 1.2 1.4 1.3 0.9 0.0 0.1 0.9 0.6 0.5 -0.8 1.4 -2.1 -1.3
Illnesses of father: None of the above (group 1) 1.3 1.6 5.7 1.7 -0.6 -0.3 -1.0 -1.5 0.5 1.7 -0.0 -2.0 -0.5 1.0 2.4 -0.7 1.1
Smoking status: Current 0.2 0.3 1.3 0.1 0.1 -0.4 -0.4 -0.3 1.1 0.1 -0.7 -0.2 -1.1 -0.7 0.0 0.3 0.4
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.1 0.3 1.1 -0.2 -0.5 0.1 -0.0 1.0 0.2 -0.8 -0.1 0.3 -0.6 1.1 -0.0 0.3 -0.5
Whole body water mass 1.0 5.4 10.6 -2.5 2.3 2.1 2.9 2.4 1.6 -1.9 2.1 1.6 1.0 -3.0 1.7 -3.2 -2.9
Leg predicted mass (right) 1.6 8.3 15.8 -3.4 2.3 2.4 3.5 3.2 0.9 -3.0 2.5 2.6 2.2 -3.6 1.9 -3.3 -4.0
Arm fat mass (left) 2.0 8.1 20.2 -3.1 1.4 1.3 2.8 1.9 -0.6 -4.2 2.6 3.3 2.0 -3.9 3.2 -1.8 -4.5
Number of self-reported non-cancer illnesses 0.2 0.4 2.5 -0.4 0.5 -0.6 0.1 -0.2 -0.6 -0.3 -0.6 0.1 -0.7 -1.6 0.2 0.2 -0.8
Average weekly champagne plus white wine intake 1.6 2.3 4.6 -1.4 1.0 2.1 2.0 2.1 -0.1 -1.1 1.9 1.4 1.8 -0.5 0.9 -1.5 -1.6
Miserableness 0.7 1.3 5.0 -0.3 -1.1 -1.6 -0.6 -0.1 0.7 -0.8 0.2 1.6 -0.9 -0.6 -1.8 2.2 0.1
Guilty feelings 1.2 1.8 4.5 1.8 -0.0 -0.1 -1.0 -1.7 -0.4 2.1 0.2 -0.8 -1.6 2.1 -1.0 0.9 1.7
Wears glasses or contact lenses 0.2 0.2 1.2 -0.4 0.3 0.3 0.3 0.3 -1.1 -0.4 -0.0 -0.0 0.0 -0.2 0.1 0.5 -0.6
Ever taken oral contraceptive pill 0.1 0.1 0.7 -0.5 0.2 -0.1 0.1 0.1 -0.8 -0.2 0.2 0.5 0.4 0.2 -0.1 0.1 -0.4
Hearing aid user 1.0 1.1 3.4 -0.3 -0.7 0.0 -0.1 1.8 -1.2 0.2 -1.1 0.6 0.9 1.7 -1.5 1.5 0.4
Mother’s age at death 0.5 0.6 4.2 0.1 0.3 0.9 0.2 0.5 2.1 -0.1 -1.0 -0.6 -0.7 0.2 0.1 -0.6 -0.6
Financial situation satisfaction 1.5 1.8 4.6 -2.1 1.1 1.4 1.7 2.1 -1.1 -0.8 0.6 1.6 0.6 0.3 0.4 -0.7 -2.0
Tinnitus: Yes, now most or all of the time 0.8 0.9 2.2 -0.0 -1.3 -1.5 -1.0 -1.2 -0.6 -1.1 -0.2 1.2 0.9 -0.1 1.0 1.2 0.3
Commuting to job workplace: Public transport 0.8 0.9 2.7 0.6 -1.3 -1.0 -1.3 -1.6 -0.2 0.2 -0.4 -1.0 -0.4 0.3 1.6 1.0 0.6
Eye problems/disorders: Glaucoma 1.0 1.1 4.6 0.1 1.4 2.1 1.1 0.6 -0.7 1.5 1.3 -0.3 1.2 -0.0 -0.5 -1.2 0.3
Medication: Blood pressure 0.2 0.3 1.4 0.6 0.3 0.2 0.1 -0.2 0.1 0.1 -1.0 -0.5 -1.2 -0.9 0.1 -0.5 -0.3
Pain type(s) experienced in last month: Hip pain 0.7 0.9 2.2 0.5 -0.8 -0.5 -1.3 -1.2 -0.7 1.3 0.3 -0.3 -1.0 1.4 0.5 0.9 1.5
Supplements: Fish oil (including cod liver oil) 0.9 1.2 2.9 1.7 1.2 1.6 0.1 0.0 0.3 1.4 -0.4 -1.5 -1.4 1.0 0.6 -1.3 0.6
High cholesterol (Self-reported) 1.1 2.0 7.5 -2.7 0.8 0.5 1.3 1.2 -0.3 -1.6 -0.1 1.8 1.4 -1.7 0.2 -1.3 -2.0
Medication: Bendroflumethiazide 0.4 0.6 3.3 -0.5 -0.6 -0.5 0.0 -0.4 -0.2 -1.8 0.4 0.7 0.5 -0.9 0.3 0.3 -1.5
Medication: Paracetamol 0.3 0.5 2.1 0.6 -0.4 -0.6 -0.3 -0.8 1.0 0.2 -0.5 0.7 -1.5 0.1 -0.5 0.7 0.5
Medication: Lisinopril 0.5 0.7 4.8 0.1 0.5 -0.4 0.4 -0.6 -1.6 0.1 -0.6 -0.2 0.7 -2.2 0.4 -0.0 -0.5
Medication: Atorvastatin 0.9 1.1 3.8 -1.2 -1.5 -1.9 -0.9 0.1 -0.0 -1.4 -1.3 0.8 0.8 -1.0 0.5 1.1 -0.4
Illnesses of father: High blood pressure 0.4 0.5 1.6 -1.1 0.5 0.2 0.9 1.3 0.3 -0.5 0.2 0.7 0.5 -0.7 -0.6 -0.1 -0.6
Alcohol drinker status: Never 0.7 0.9 4.4 0.7 -0.6 -0.8 -0.4 -0.3 1.8 -0.7 -2.1 -0.6 -1.1 -1.0 -0.1 0.3 -0.3
Ever smoked 0.6 1.1 3.1 0.4 -0.3 -1.3 -1.1 -0.7 -0.6 0.2 -0.5 -1.5 -1.6 0.4 -1.5 1.8 0.3
Basal metabolic rate 1.2 6.4 11.6 -2.9 2.2 2.0 3.0 2.5 1.2 -2.6 2.4 2.0 1.4 -3.4 2.1 -3.2 -3.4
Leg fat percentage (left) 1.2 4.4 12.7 -1.8 0.3 0.3 1.3 0.6 -1.4 -3.6 1.8 2.8 1.9 -2.5 3.3 -0.7 -3.2
Arm fat-free mass (left) 0.8 4.3 9.2 -2.3 1.9 1.4 2.4 1.8 1.7 -2.0 1.7 1.5 0.6 -3.0 1.7 -2.8 -2.6
Number of operations (self-reported) 0.3 0.5 2.2 -1.5 0.4 0.7 0.6 0.5 0.1 0.3 0.2 0.6 1.0 -1.0 0.4 -0.9 0.0
Average weekly beer plus cider intake 2.0 2.9 7.7 1.3 -1.9 -2.6 -2.4 -2.8 -0.8 0.9 -1.9 -0.9 -0.1 1.1 -0.0 2.2 1.6
Irritability 1.9 3.3 6.2 2.2 -1.1 -2.0 -2.3 -2.3 -0.6 1.3 -1.9 -1.7 -2.5 1.8 -1.0 1.9 1.6
Risk taking 0.9 1.3 4.8 0.1 -0.9 -0.8 -0.8 -0.8 -2.1 0.4 0.3 0.4 -0.4 1.6 -1.4 2.2 0.8
Ever had prostate specific antigen (PSA) test 0.7 0.8 6.2 -0.7 0.2 -0.0 0.5 0.9 2.5 -0.3 -1.1 0.1 -0.8 -0.8 -0.5 -0.3 0.0
Fractured/broken bones in last 5 years 0.5 0.6 2.2 -0.9 -0.6 0.4 -0.4 0.2 -0.6 0.1 0.9 1.2 1.5 0.7 0.6 -0.8 1.0
Age started oral contraceptive pill 1.2 1.5 5.1 2.2 -0.8 -0.3 -1.1 -1.2 -2.2 1.1 -0.7 -0.8 0.3 2.1 -0.4 0.2 0.7
Diastolic blood pressure, automated reading 1.1 3.3 14.7 -2.3 0.5 -0.2 1.6 0.9 1.1 -2.2 1.3 3.0 0.2 -3.8 0.4 -0.4 -2.1
Ever depressed for a whole week 0.2 0.2 1.1 -0.3 0.3 0.0 0.1 -0.1 -0.3 1.1 -0.7 0.1 0.6 0.2 -0.8 0.2 0.3
Unable to work because of sickness or disability 1.2 1.6 5.5 0.6 -1.1 -1.7 -1.6 -2.3 0.9 0.7 -0.3 -0.7 -1.0 -0.1 -0.2 1.6 1.9
Commuting to job workplace: Cycle 1.6 1.9 6.4 -1.2 0.2 1.0 1.6 2.5 0.4 -1.5 -0.3 1.0 2.3 -0.7 -0.9 -1.5 -1.7
Myopia 0.4 0.6 2.1 0.7 -0.2 -0.4 -0.6 -0.4 -0.1 0.4 -0.8 -1.0 -1.1 1.2 1.4 0.5 0.0
Vascular/heart problems diagnosed by doctor 0.5 1.4 7.8 1.1 -0.4 0.6 -0.5 0.0 -0.9 1.2 0.7 -0.4 1.4 2.8 -1.0 0.3 1.9
Cholesterol lowering medication 0.6 0.8 2.8 -1.1 0.2 0.3 0.7 0.6 -0.7 -1.1 -0.2 1.1 1.3 -1.7 -0.6 -0.8 -1.1
Medication: Omeprazole (e.g. Zanprol) 3.0 3.6 7.3 2.5 -2.4 -2.5 -2.3 -1.3 0.6 0.2 -2.7 -1.8 -1.9 1.9 -0.0 2.4 1.3
Pain experienced in last month 0.7 1.1 2.6 -0.4 1.3 1.4 1.0 0.4 -1.0 0.0 1.5 0.4 1.4 -0.1 1.6 -1.5 -0.3
Supplements: Calcium 0.3 0.3 1.0 0.9 -0.6 -0.4 -0.4 -0.2 0.8 0.7 -1.0 -0.2 -0.8 0.5 -0.1 0.1 0.4
Basal cell carcinoma (self-reported) 0.4 0.4 2.2 -0.3 0.7 0.7 0.5 1.0 -0.1 -0.7 0.1 -0.3 0.5 -0.7 -1.5 0.1 -0.2
Heart attack/myocardial infarction (self-reported) 2.8 3.6 7.2 -2.7 2.4 1.8 2.6 2.4 0.4 -1.5 2.2 1.4 0.7 -2.5 -0.4 -1.1 -2.3
Deep venous thrombosis (DVT) (self-reported) 0.8 1.0 3.1 1.5 -0.4 0.0 -1.0 -1.2 -0.7 1.4 -0.5 -1.1 -0.3 1.8 0.3 0.6 1.4
Heart disease (siblings) 0.6 0.7 2.0 0.6 -0.8 -1.2 -1.3 -0.9 -0.0 -0.2 -0.4 -0.5 -0.8 0.3 -1.1 1.4 0.7
Alcohol drinker status: Previous 2.1 2.4 6.8 -0.6 -0.9 -1.3 0.6 0.5 -1.6 -2.6 1.7 2.1 1.8 -2.0 1.4 0.9 -1.9
Pack years of smoking 0.7 1.1 4.8 0.3 -0.5 -1.1 -0.7 -0.7 2.2 -0.0 -0.9 -0.8 -1.5 -1.2 -1.0 1.0 0.5
Impedance of whole body 0.3 1.5 8.8 -0.9 -0.7 0.4 0.1 1.0 -2.0 -0.9 0.2 1.5 3.0 1.5 -0.3 0.5 -0.5
Leg fat mass (left) 1.5 6.0 14.4 -2.5 1.0 1.0 2.1 1.2 -0.5 -3.7 2.4 2.6 1.9 -3.2 3.6 -1.7 -3.8
Arm predicted mass (left) 0.8 4.3 9.2 -2.1 2.0 1.6 2.5 1.8 1.7 -1.9 1.8 1.3 0.6 -3.0 1.8 -2.9 -2.7