Hub : Genes

PAK1

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0670	0.0260	2.9e-04	0.043	0.019	0.046	0.025	0.032	4.7e-06	2.1e-03	2.6e-06	4.5e-04	7.6e-05
2	GTEx	Artery Aorta	0.1060	0.0410	9.5e-04	0.129	NA	0.076	NA	0.110	1.4e-07	NA	5.4e-05	NA	1.2e-06
3	GTEx	Artery Coronary	0.1520	0.0620	2.8e-03	0.018	NA	-0.007	NA	0.013	8.0e-02	NA	6.6e-01	NA	1.1e-01
4	GTEx	Artery Tibial	0.1719	0.0412	6.6e-10	0.129	NA	0.197	NA	0.196	2.8e-10	NA	2.4e-15	NA	2.9e-15
5	GTEx	Esophagus Mucosa	0.2880	0.0660	2.3e-11	0.148	NA	0.210	NA	0.207	4.4e-10	NA	4.3e-14	NA	7.1e-14
6	GTEx	Testis	0.1710	0.0640	5.4e-04	0.096	NA	0.074	NA	0.088	5.0e-05	NA	3.3e-04	NA	9.8e-05
7	GTEx	Thyroid	0.5830	0.0610	1.7e-16	0.194	NA	0.216	NA	0.249	8.6e-15	NA	1.7e-16	NA	5.0e-19
8	GTEx	Uterus	0.3340	0.1000	3.1e-04	0.042	NA	0.099	NA	0.086	5.0e-02	NA	4.9e-03	NA	8.3e-03
9	METSIM	Adipose	0.0802	0.0286	6.5e-06	0.030	0.040	0.034	0.040	0.023	2.3e-05	1.2e-06	6.7e-06	1.2e-06	1.8e-04
10	NTR	Blood	0.0177	0.0098	7.7e-03	-0.001	0.004	0.003	0.004	0.000	7.0e-01	1.2e-02	3.8e-02	1.1e-02	2.7e-01
11	ROSMAP	Brain Pre-frontal Cortex	0.0970	0.0329	8.1e-07	0.045	0.047	0.024	0.048	0.031	1.5e-06	9.5e-07	4.3e-04	7.3e-07	6.4e-05
12	YFS	Blood	0.1826	0.0458	3.4e-07	0.028	0.018	0.034	0.035	0.025	1.8e-09	9.7e-07	1.8e-11	1.3e-11	1.2e-08
13	TCGA	Prostate Adenocarcinoma	0.0595	0.0379	7.1e-04	0.022	0.024	0.010	NA	0.024	1.9e-03	1.4e-03	2.7e-02	NA	1.5e-03
14	TCGA	Thyroid Carcinoma	0.0430	0.0330	8.2e-03	0.013	0.019	0.003	NA	0.025	1.6e-02	5.4e-03	1.6e-01	NA	1.5e-03

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14
Bipolar Disorder (2018)	0.4	0.7	2.9	0.2	-0.2	-1.0	-0.4	0.2	0.3	-0.4	-0.6	-0.2	-1.7	0.5	-1.4	1.6	-0.0
Bipolar Disorder or Schizophrenia	0.1	0.1	0.5	-0.1	-0.2	-0.4	0.0	-0.1	0.0	-0.4	0.0	0.7	0.3	0.4	0.3	0.7	-0.4
Depressed Affect (Nagel 2018)	0.6	1.3	5.7	0.9	-0.8	-1.7	-1.0	-1.0	-0.2	-0.1	-0.3	0.5	-1.5	-0.3	-1.8	2.4	0.3
Depression (Nagel 2018)	1.8	2.7	5.3	1.6	-0.8	-1.2	-1.9	-2.0	-0.1	2.0	-0.9	-1.1	-2.0	1.5	-1.9	1.9	2.3
Intelligence (Savage-Jansen 2018)	0.6	1.8	5.6	2.2	0.5	0.6	-0.6	-1.6	-0.8	2.4	-1.0	-1.1	-0.8	2.1	-0.7	-0.1	1.7
Neuroticism (Nagel 2018)	1.5	3.5	7.7	2.3	-0.9	-1.9	-1.9	-2.0	-0.2	1.2	-1.4	-1.1	-2.8	1.6	-2.6	2.8	1.5
Schizophrenia (2018)	0.3	0.6	3.4	-0.3	-0.0	0.2	0.3	-0.3	-0.2	-0.2	0.6	1.1	1.8	0.1	1.5	-0.4	-0.5
Schizophrenia vs Biploar Disorder	1.4	1.8	7.7	-0.2	1.2	1.3	1.1	0.2	-2.0	-0.4	0.6	0.8	2.8	-0.2	1.8	-2.0	-0.9
Worry (Nagel 2018)	1.4	3.0	6.3	2.5	-1.0	-1.5	-1.8	-1.6	-0.1	1.4	-2.0	-1.5	-1.8	1.9	-2.0	2.2	1.7
Alzheimer’s Disease (in mother)	0.3	0.3	2.8	-0.3	-0.0	0.4	-0.0	-0.1	-0.3	-0.4	0.7	0.5	1.7	0.5	-0.2	-0.5	0.1
Alzheimer’s Disease (in father)	0.6	0.7	3.6	0.2	1.0	0.9	-0.0	0.1	-0.0	1.5	0.2	-0.5	-1.9	0.2	-0.5	-0.4	1.0
Alzheimer’s Disease (including proxy)	0.1	0.1	0.4	-0.1	-0.1	0.4	-0.3	-0.2	0.1	0.3	0.5	0.3	0.4	0.5	0.1	-0.2	0.6
Crohns Disease (2017)	0.1	0.3	0.8	-0.4	-0.6	-0.6	-0.5	-0.3	0.5	0.9	-0.7	0.1	-0.6	0.1	0.6	0.3	0.5
Irritable Bowel Disease (IBD)	0.2	0.4	1.2	-0.2	-0.6	-0.7	-0.6	-0.6	0.8	1.1	-0.5	0.0	-0.9	-0.0	0.7	0.3	0.6
Ulcerative Colitis (UC)	0.2	0.4	1.7	0.2	-0.3	-0.8	-0.5	-0.8	0.4	0.7	-0.5	-0.0	-1.3	0.0	0.4	0.5	0.6
Major Depression (MDD)	0.7	0.8	2.7	0.2	-0.8	-0.5	-0.9	-0.3	0.2	0.7	0.2	-0.1	-1.6	1.4	-1.1	1.3	1.1
Reaction Time	0.7	1.3	5.5	0.5	1.4	0.7	0.3	-0.5	1.1	2.3	-0.3	-1.7	-1.8	0.2	-0.9	-0.4	1.2
Verbal and Numeric Reasoning (VNR)	0.9	2.0	5.6	2.2	1.2	1.4	-0.3	-0.9	-0.9	2.4	-0.6	-1.2	-1.4	2.2	-1.3	-0.4	1.7
Breast Cancer	1.1	2.7	6.3	-2.4	2.5	1.5	2.2	1.5	0.8	-0.4	1.6	1.1	-0.6	-2.3	0.4	-2.1	-1.5
Ovarian Cancer	0.7	0.9	2.9	0.7	-1.7	-0.9	-1.5	-0.8	0.2	0.3	-1.2	-0.4	1.0	1.2	-0.1	0.9	0.8
Prostate Cancer	0.5	0.8	1.8	-0.6	-0.6	-1.0	-0.6	0.0	1.3	-0.8	-1.4	-1.3	-0.8	-1.2	0.2	0.4	-0.6
Age at First Birth	0.6	0.9	3.3	0.9	-0.6	0.1	-1.0	-1.3	-1.1	1.1	-0.3	-0.3	1.0	1.8	0.3	-0.1	1.3
Bipolar Disorder (2011)	0.6	0.6	4.1	-0.6	1.0	0.6	0.3	0.3	0.6	1.0	0.6	0.1	-2.0	0.6	-0.3	0.2	0.3
Body Mass Index (BMI) (2010)	0.5	0.7	2.6	-0.8	-1.0	-1.6	-1.1	-0.9	1.1	-0.8	0.1	0.0	-0.9	-0.2	-0.0	1.1	0.4
Coronary Artery Disease (CAD)	1.4	1.7	4.8	-1.4	0.6	0.5	1.6	1.8	0.0	-1.7	0.8	1.9	0.9	-1.4	0.1	-0.6	-2.2
Crohns Disease (2012)	1.1	1.8	4.3	-1.3	1.2	1.5	1.6	1.1	-0.2	-0.6	1.4	2.1	0.9	-1.2	1.9	-1.7	-1.3
Mean Putamen Volume	0.7	0.8	2.7	0.1	-1.1	-1.6	-0.5	0.8	0.3	-0.2	-1.0	-0.6	-0.3	0.4	-1.4	1.5	0.2
Fasting Glucose	0.3	0.4	1.8	-0.2	0.1	-0.3	0.2	-0.0	0.1	-0.5	0.0	0.8	1.0	-1.4	0.8	-0.7	-0.3
HbA1C	0.4	0.4	2.6	-0.9	-0.2	0.3	0.1	0.3	0.5	-0.5	1.6	0.6	0.7	-0.2	0.3	-0.5	0.3
HDL Cholesterol	0.9	1.4	7.1	-1.3	-0.3	-0.2	0.8	0.2	-0.1	-1.6	0.6	1.6	2.7	-2.0	0.2	-0.4	-0.9
LDL Cholesterol	0.4	0.6	2.4	-0.5	0.4	0.5	0.2	0.0	-0.3	-0.7	1.5	1.1	1.3	0.3	1.4	-0.4	-0.2
Lupus	0.8	1.2	3.4	-1.1	0.7	1.3	1.2	1.8	0.7	-1.1	-0.1	0.9	0.6	-1.1	0.8	-1.4	-1.5
Neuroticism (2016)	0.4	0.5	1.9	0.7	0.9	1.4	0.6	0.2	-1.0	0.4	0.9	1.1	0.2	-0.1	0.7	-0.5	0.1
Primary Biliary Cirrhosis	0.2	0.3	3.1	0.5	-0.4	-0.2	-0.4	0.4	-0.4	0.3	-0.5	-0.2	-0.2	1.8	-0.1	-0.1	0.8
Rheumatoid Arthritis	0.4	0.6	2.6	-0.2	-0.2	-1.6	-0.7	-1.6	-0.2	0.0	-0.8	-0.2	-0.3	-0.5	-0.7	0.5	1.0
Schizophrenia (2014)	0.3	0.7	2.0	0.6	-0.2	-0.3	-0.6	-1.4	-1.2	1.0	0.6	-0.1	0.7	1.1	1.4	0.3	1.0
Triglycerides	0.2	0.3	0.9	0.7	0.3	-0.2	-0.2	-0.3	0.2	0.4	0.6	-1.0	-0.6	0.9	0.6	-0.7	0.5
Type 2 Diabetes (T2D) (2012)	0.6	0.7	2.6	-1.1	0.1	-0.9	0.0	-0.4	0.0	-1.3	1.6	0.7	0.8	-1.2	0.4	0.0	-0.7
Ulcerative Colitis	1.0	1.5	3.8	1.4	-1.3	-1.3	-1.7	-2.0	-0.5	1.1	-0.8	-0.4	-1.0	0.8	0.9	1.1	1.5
Blood Eosinophil Count	0.7	5.7	20.7	-2.6	-0.1	-0.8	1.8	2.5	1.1	-4.2	0.9	2.4	2.1	-4.5	0.3	-0.1	-3.5
Blood Platelet Count	1.3	14.9	34.2	3.2	-3.8	-5.2	-4.9	-5.1	-0.5	2.2	-3.7	-2.9	-4.8	1.4	-1.7	5.8	4.1
Blood Red Count	0.1	0.7	3.1	-1.8	-1.2	-1.1	-0.6	0.4	1.0	-0.1	-0.6	0.2	0.1	0.0	-0.7	1.4	0.4
Blood White Count	0.2	1.7	5.5	-0.2	-1.6	-1.7	-1.5	-1.1	1.5	-0.4	-2.3	-1.5	-0.6	-0.1	-0.3	2.0	0.3
Heel T-Score	0.8	6.5	19.4	2.4	-3.5	-4.4	-3.4	-2.6	-2.4	0.5	-2.7	-1.9	-0.8	0.6	-1.1	3.6	1.9
BMI	0.8	4.5	11.5	-2.4	1.2	0.7	2.2	0.9	0.1	-2.9	2.3	2.0	0.9	-3.4	2.7	-1.3	-3.4
Height	0.9	16.8	34.0	-5.7	3.1	4.4	4.7	5.8	2.3	-3.0	3.3	3.4	5.3	-2.4	1.0	-5.1	-4.5
Waist Hip Ratio (WHR)	0.3	1.4	4.5	0.2	-0.9	-1.6	-1.0	-1.3	2.1	0.4	-2.1	-0.7	-1.8	-0.3	-0.2	0.9	0.4
Systolic Blood Pressure	0.3	1.6	7.0	-1.6	-0.2	-0.1	0.8	0.6	0.7	-1.9	-0.3	2.6	0.8	-1.1	1.8	-0.3	-1.6
Smoking Status	0.4	1.1	4.7	-1.2	-0.4	-1.1	0.2	0.9	0.5	-2.2	-0.8	0.9	0.3	-1.7	-0.5	0.8	-1.1
Allergy or Eczema	1.2	3.2	9.9	1.2	-1.5	-1.7	-1.9	-2.2	-1.7	1.4	-0.5	-0.2	-1.5	1.3	-2.1	3.1	2.5
Cardiovascular Disease	0.5	1.8	10.6	-1.1	-0.1	-1.2	0.3	-0.2	1.5	-1.5	-1.3	1.2	-0.6	-3.2	0.0	0.2	-1.9
Hypothyroidism (self reported)	0.4	0.9	5.7	-0.4	-0.8	-1.1	-0.2	0.2	-0.8	-0.7	-0.9	0.5	-0.7	-0.6	-2.4	1.2	-0.6
Respiratory disease	0.9	2.1	6.4	1.5	-1.3	-1.7	-1.8	-2.2	-1.1	0.7	-1.3	-0.4	-1.6	0.3	-0.4	2.5	1.3
Type 2 Diabetes (T2D) (2018)	0.3	0.6	2.5	0.1	-0.8	-1.0	-0.1	0.1	0.2	-1.3	-0.6	-0.1	0.0	-1.6	1.0	-0.1	-1.2
Lung FEV1/FVC ratio	0.3	1.7	4.2	-1.8	-1.5	-1.8	-0.1	0.3	1.5	-2.1	0.2	1.7	0.4	-1.5	0.2	1.0	-1.1
Lung FVC	0.2	1.2	5.2	1.7	0.6	0.9	-0.4	-0.6	-0.6	1.4	-0.2	-2.3	-1.4	1.2	0.1	0.3	0.9
Neuroticism	0.7	1.6	4.9	1.4	-0.6	-0.9	-1.3	-0.9	0.6	1.1	-1.3	-0.7	-2.2	1.5	-1.7	1.3	1.1
Chronotype (morning person)	1.2	2.9	6.4	-2.3	1.9	1.6	2.2	1.6	-0.4	-1.6	0.3	1.4	1.3	-2.0	1.5	-1.3	-2.5
Hair Pigment	0.2	6.6	17.6	0.9	-3.3	-3.6	-2.9	-2.3	4.2	1.6	-3.2	-2.6	-2.5	0.0	-0.8	2.3	2.3
Tanning	0.1	0.8	1.9	-1.3	1.1	1.4	1.1	1.3	0.4	-0.2	0.5	0.3	0.7	-0.6	-0.8	-1.0	-0.8
Hand grip strength (left)	0.7	1.8	7.9	-0.1	1.2	1.8	0.9	0.2	-0.8	0.2	2.3	0.4	2.0	-0.2	0.9	-2.8	0.1
Number of treatments/medications taken	0.5	1.0	3.9	-0.6	-0.2	-0.9	-0.2	-0.7	0.8	-1.1	-0.4	0.8	-2.0	-1.7	0.6	0.9	-1.1
Average weekly spirits intake	0.5	0.6	1.6	-0.9	0.6	0.2	0.8	0.7	0.7	-1.1	0.6	0.9	-0.4	-1.3	0.4	-0.1	-1.1
Sensitivity / hurt feelings	1.5	2.6	12.1	0.1	-0.7	-1.4	-0.3	1.3	2.8	-0.5	-2.2	-0.3	-2.5	0.3	-3.5	1.0	0.5
Frequency of depressed mood in last 2 weeks	1.0	1.4	3.8	0.6	-0.5	-1.1	-1.4	-1.0	0.1	1.5	-0.8	-0.4	-1.9	0.7	-1.2	1.4	1.8
Hearing difficulty/problems: Yes	0.9	1.4	5.9	0.2	0.3	1.4	0.0	0.2	-0.9	2.0	-1.1	0.6	1.4	2.4	-0.8	0.0	1.2
Relative age of first facial hair	0.3	0.7	2.3	0.3	0.7	1.5	0.4	0.9	-0.1	0.8	1.3	-0.1	0.6	1.1	-0.7	-0.5	0.7
Other serious medical condition/disability diagnosed by doctor	0.6	0.7	2.5	0.5	-0.9	-1.1	-1.2	-1.6	-0.6	0.1	0.5	-0.5	-0.6	-0.3	-0.4	1.3	0.9
Ever used hormone-replacement therapy (HRT)	0.2	0.3	1.6	0.7	0.3	0.3	-0.0	-0.5	-1.1	0.1	0.3	0.2	-0.1	0.1	-1.3	0.1	0.1
Ever had hysterectomy (womb removed)	0.4	0.4	1.2	0.4	0.7	1.1	0.5	-0.2	-1.0	0.5	1.0	0.5	1.0	-0.2	-0.1	-0.5	0.1
Systolic blood pressure, automated reading	0.2	0.7	2.6	-0.2	0.4	0.5	0.7	0.4	-0.3	-1.2	-0.1	1.6	-0.3	-0.9	1.2	-0.5	-1.1
Eye problems/disorders: Diabetes related eye disease	0.2	0.2	1.0	0.0	-0.1	0.1	0.2	-0.0	0.7	-0.2	-0.1	0.2	0.1	-1.0	0.3	-0.8	-0.3
Angina	1.0	1.3	2.9	-0.5	1.6	1.2	1.7	1.6	-0.7	-0.9	1.4	0.5	0.2	-1.1	-0.2	-1.2	-1.7
Medication for hormone replacement therapy	0.4	0.4	1.4	-0.9	-0.4	-0.5	0.1	0.3	0.5	-0.5	0.6	1.2	-0.4	-0.1	-0.7	1.1	-0.3
Vitamin and mineral supplements	1.9	2.6	7.0	-0.9	2.1	2.0	2.3	1.9	-1.1	0.3	2.6	0.3	1.7	-1.4	-1.0	-1.7	-1.0
Supplements: Zinc	0.5	0.5	2.1	-1.3	-0.3	-0.5	-0.0	0.9	-0.4	-1.4	0.9	0.9	0.4	-0.1	-0.4	0.1	-0.5
Medication: Co-codamol	0.2	0.3	1.6	-0.5	-0.1	-0.2	0.1	0.1	0.1	-0.6	1.0	0.5	0.2	-1.3	-0.2	0.1	-0.3
Medication: Metformin	0.4	0.6	3.0	0.2	0.3	0.2	0.3	-0.4	-1.7	-0.4	1.0	0.0	1.0	-0.8	1.2	-0.3	-0.6
Diabetes (father)	1.1	1.4	7.2	-1.1	-1.1	-1.3	-0.1	0.9	2.7	-0.4	-0.4	-0.3	0.8	-0.9	-2.1	0.8	0.3
Diabetes (mother)	0.8	1.1	2.6	1.4	-1.2	-0.9	-1.6	-1.5	0.5	0.6	-0.9	-0.5	-0.9	0.5	-0.1	1.0	1.5
Severe depression (siblings)	1.4	1.5	5.4	0.5	-1.2	-1.8	-1.4	-1.3	1.0	-0.4	-1.2	-0.2	-2.3	0.4	-0.6	2.0	0.6
Pack years adult smoking proportion	0.7	1.0	3.9	0.3	-0.4	-1.0	-0.7	-0.8	2.0	0.2	-0.9	-0.8	-1.5	-1.2	-1.0	0.8	0.7
Impedance of leg (right)	0.2	0.9	4.2	0.7	-1.2	-0.7	-1.1	-0.8	-0.9	0.4	-0.2	-0.1	1.0	2.0	-0.4	1.1	1.0
Leg fat-free mass (left)	1.4	7.4	14.4	-3.2	2.3	2.2	3.4	2.9	0.8	-2.8	2.6	2.4	1.8	-3.4	2.0	-3.1	-3.8
Trunk fat percentage	2.4	9.6	23.9	-3.2	0.7	1.2	2.5	2.0	-1.9	-4.9	2.8	3.9	3.3	-3.1	4.0	-1.3	-4.9
Hand grip strength (right)	1.5	4.0	14.3	-0.9	2.0	2.6	2.2	1.6	-0.8	-0.5	2.5	1.6	3.1	-0.9	1.3	-3.8	-1.1
Townsend deprivation index at recruitment	1.1	1.5	6.7	1.4	-1.1	-1.7	-1.2	-1.7	-1.6	-0.3	-0.3	-0.2	-0.8	0.7	-0.5	2.6	0.5
Current tobacco smoking	0.2	0.3	1.7	0.3	-0.0	-0.5	-0.4	-0.4	1.3	0.1	-0.8	-0.2	-0.7	-0.8	0.1	0.3	0.5
Average weekly fortified wine intake	0.6	0.7	3.1	-0.8	-0.6	-0.0	0.4	0.7	0.1	-1.2	1.1	1.0	1.8	-0.6	-0.3	-0.4	-0.7
Maternal smoking around birth	0.5	0.8	3.2	0.3	1.3	0.4	0.8	0.6	-1.8	-0.6	1.1	-0.3	-0.9	-0.6	-0.9	0.6	-0.8
Fed-up feelings	0.7	1.3	4.6	-0.3	-1.1	-2.1	-0.8	-0.3	0.8	-0.8	0.1	0.6	-1.8	-1.2	-0.8	2.0	-0.1
Frequency of unenthusiasm / disinterest in last 2 weeks	1.1	1.4	3.0	1.3	-1.0	-1.6	-1.3	-1.5	1.0	0.9	-1.2	-0.6	-1.0	0.1	-1.1	1.7	1.5
Relative age voice broke	1.2	1.9	9.1	0.7	2.0	3.0	1.4	1.1	0.2	1.2	1.9	-0.3	0.1	0.7	0.4	-1.9	-0.1
Taking other prescription medications	0.9	1.3	4.8	-1.3	1.1	0.5	1.3	0.9	0.9	-1.1	0.5	1.4	-0.2	-2.2	0.7	-0.6	-1.8
Age when periods started (menarche)	0.9	2.2	8.3	-2.9	0.9	0.6	0.9	0.1	1.3	-0.3	1.4	1.8	2.8	-0.9	1.2	-1.8	-0.7
Bilateral oophorectomy (both ovaries removed)	1.3	1.5	3.3	-1.2	0.2	0.0	1.4	1.2	-0.3	-1.4	1.6	1.6	1.8	-1.6	-0.5	-0.4	-1.6
Heel bone mineral density (BMD) T-score, automated (left)	0.5	1.2	4.5	1.3	-1.2	-1.2	-0.9	-0.6	-1.3	0.4	-2.1	-1.2	-0.6	0.9	0.1	1.2	0.4
Tinnitus: Yes, but not now, but have in the past	3.3	3.5	9.1	-2.8	1.3	0.5	1.9	3.0	0.8	-1.9	1.6	2.4	0.2	-2.2	-2.4	-0.6	-1.8
Qualifications: CSEs or equivalent	1.9	2.4	6.8	-1.9	-0.1	0.2	1.3	2.1	1.7	-2.6	-0.3	2.2	1.7	-1.2	-0.0	-1.1	-2.0
Serious illness, injury or assault to yourself	0.5	0.6	1.5	-0.7	-0.8	-0.5	0.2	-0.5	0.3	-1.2	0.4	1.2	1.2	-0.5	1.1	0.6	-0.7
High blood pressure	0.4	1.0	4.8	0.2	-0.1	-0.9	-0.4	-0.9	1.0	-0.0	-1.6	-0.7	-2.2	-1.6	0.8	0.1	-0.8
Hayfever, allergic rhinitis or eczema	0.8	1.6	6.3	0.1	-1.3	-1.5	-1.1	-1.4	-0.7	0.5	-0.5	0.4	-1.1	0.6	-2.2	2.5	1.5
Multivitamins +/- minerals	3.3	4.2	8.8	1.3	-2.9	-2.9	-3.0	-1.9	1.8	-0.2	-2.9	-0.6	-2.3	1.6	0.7	2.4	1.4
Stomach or abdominal pain in last month	1.0	1.2	3.2	-1.0	-0.6	-1.2	0.5	1.7	1.3	-1.8	-0.7	0.4	-0.9	-1.2	-0.2	0.3	-1.6
Supplements: Glucosamine	0.6	0.7	3.9	1.3	0.3	0.3	-0.6	-0.5	0.8	0.3	-0.4	-1.1	-2.0	1.2	0.6	-0.2	0.3
Diverticular disease/diverticulitis (self-reported)	0.9	1.1	6.9	1.0	0.2	0.8	-0.3	-0.4	-2.6	0.4	0.8	0.6	0.4	2.3	-0.0	0.3	0.4
Medication: Atenolol	0.6	0.7	5.8	0.1	-0.2	-0.7	-0.3	0.2	1.0	0.3	-0.8	0.3	-2.4	-0.1	-1.1	0.6	0.4
Medication: Levothyroxine sodium	0.6	1.1	4.3	0.4	-1.3	-1.4	-1.0	-0.3	-1.1	-0.2	-0.8	-0.2	-0.6	0.4	-2.1	1.7	0.5
Sitting height	1.0	6.8	14.5	-3.8	2.0	1.6	3.1	3.0	0.2	-2.5	2.2	3.3	2.9	-3.5	-0.3	-2.0	-2.9
Chronic bronchitis/emphysema (father)	0.9	1.0	5.9	0.6	-0.8	-1.4	-0.9	-0.5	-0.5	-1.5	-2.4	-0.3	-0.1	-0.9	0.1	0.7	-0.4
High blood pressure (mother)	1.7	2.3	8.1	0.3	-2.5	-2.5	-1.7	-0.9	2.9	-0.9	-1.5	0.2	-0.6	-0.4	0.6	2.0	0.6
Body mass index (BMI)	0.8	3.4	8.8	-1.6	0.5	0.4	1.4	0.5	-0.8	-2.9	1.7	1.9	0.8	-2.9	3.0	-0.7	-2.9
Impedance of leg (left)	0.2	0.8	3.4	0.3	-1.1	-0.4	-0.8	-0.4	-1.2	-0.2	-0.1	0.5	1.8	1.6	-0.1	0.8	0.5
Leg predicted mass (left)	1.3	6.9	13.5	-3.1	2.2	2.1	3.2	2.8	0.8	-2.7	2.5	2.3	1.7	-3.3	1.9	-3.0	-3.7
Trunk fat mass	2.4	10.2	25.4	-3.5	1.3	1.6	2.9	2.3	-0.9	-4.8	2.9	3.7	3.0	-3.6	4.0	-2.0	-5.0
Waist circumference	1.2	4.3	10.6	-2.2	1.2	0.9	1.9	1.0	-0.4	-2.9	1.8	2.2	1.0	-3.1	3.0	-1.2	-3.3
Number of incorrect matches in round	0.9	1.6	8.1	-0.2	1.7	1.8	0.7	-0.5	-0.7	1.1	1.6	0.0	-0.2	-0.1	2.9	-1.6	-0.0
Past tobacco smoking	0.4	0.8	2.7	-0.0	0.8	1.6	1.0	0.6	0.5	0.8	0.9	0.7	1.2	0.2	0.6	-1.7	0.0
Alcohol usually taken with meals	2.3	3.7	8.5	-1.6	2.3	2.3	2.9	2.7	-0.1	-1.0	1.6	1.6	1.7	-1.5	-1.1	-2.6	-2.1
Nervous feelings	0.9	1.6	4.0	1.8	-0.8	-1.4	-1.4	-1.5	-0.1	0.9	-0.5	-0.4	-1.1	1.1	-2.0	1.6	1.6
Frequency of tenseness / restlessness in last 2 weeks	1.1	1.8	6.0	2.5	0.1	-0.4	-0.9	-2.0	-1.6	2.1	-0.1	-0.3	-0.9	1.2	-0.7	0.8	1.7
Hearing difficulty/problems with background noise	0.7	1.2	5.4	-0.0	0.3	1.1	-0.5	-1.0	-1.0	1.6	-0.5	0.7	0.9	2.3	-1.1	0.2	1.4
Hair/balding pattern: Pattern 2	1.7	2.2	8.6	-1.9	0.4	0.1	1.6	1.9	1.0	-1.5	0.8	2.9	0.1	-1.7	-1.6	-0.1	-1.7
Had menopause	0.5	0.6	3.9	2.0	-0.4	0.4	-0.6	-0.8	-0.4	0.8	-0.5	-0.7	-0.4	0.9	0.1	-0.0	0.6
Had other major operations	1.1	1.3	3.3	1.0	-1.8	-1.1	-1.7	-1.4	-1.1	0.4	-1.3	-0.6	0.8	0.9	0.8	0.8	1.4
Forced vital capacity (FVC)	0.6	2.5	7.2	-0.8	1.8	2.7	2.0	2.2	-0.9	-0.4	1.3	0.7	1.7	0.1	1.1	-2.3	-1.4
Heel bone mineral density (BMD) T-score, automated (right)	0.7	1.7	4.4	1.4	-1.4	-1.3	-1.5	-1.1	-1.9	1.0	-2.1	-0.8	-0.1	1.1	-0.2	1.4	1.4
Ever unenthusiastic/disinterested for a whole week	0.6	0.7	2.1	0.6	1.5	1.1	0.7	-0.2	-0.1	1.2	0.4	-0.6	-0.9	-1.4	-1.1	-0.0	0.1
Qualifications: None of the above	0.8	1.7	6.1	-0.9	-1.6	-1.6	-0.6	-0.1	1.0	-2.5	-0.5	1.1	0.6	-1.4	1.0	1.9	-1.4
Financial difficulties in last 2 years	0.3	0.4	2.3	-1.5	-0.7	-0.7	-0.3	0.6	0.6	-0.1	0.3	-0.2	-0.1	0.4	-1.1	0.4	0.2
Mouth/teeth dental problems	1.6	2.5	5.9	-2.2	1.4	1.6	1.7	0.9	0.9	-0.8	2.4	0.9	0.5	-1.2	2.4	-2.2	-1.4
Heart attack	2.8	3.6	6.9	-2.6	2.0	1.6	2.5	2.3	0.3	-1.8	2.4	1.7	0.9	-2.4	-0.2	-0.8	-2.5
Allergy	1.8	4.2	13.8	-1.8	2.5	2.8	2.5	3.0	1.2	-0.7	1.1	0.3	1.3	-0.9	1.4	-3.7	-2.2
Pain all over the body in last month	0.2	0.3	1.2	0.7	0.4	0.5	0.4	-0.1	-0.7	-0.2	-0.2	0.3	1.1	-0.4	-0.7	-0.1	-0.2
Diabetes (self-reported)	0.5	0.7	2.5	0.6	-1.2	-1.6	-1.0	-0.9	-1.1	-0.6	-0.8	0.2	-0.3	-0.4	0.3	1.1	-0.1
Hayfever/allergic rhinitis (self-reported)	0.5	0.7	3.1	-0.4	-0.5	-1.0	-0.4	0.4	0.5	-0.2	-0.2	0.8	-1.3	-0.2	-1.8	1.3	0.9
Medication: Ramipril	0.3	0.4	1.8	-0.7	0.6	-0.1	0.5	0.3	0.8	-0.6	-0.0	0.2	-0.9	-1.0	0.2	-0.3	-1.3
Medication: Simvastatin	1.1	1.6	2.7	-1.3	1.3	1.3	1.5	0.7	-1.2	-1.1	1.1	1.2	1.5	-1.5	0.6	-1.3	-1.6
Fluid intelligence score	1.2	2.4	7.5	1.0	2.0	2.2	0.6	-0.1	-1.1	2.7	0.1	-0.8	-0.6	2.4	-1.7	-1.9	1.4
Illnesses of siblings	0.5	0.8	2.2	-0.6	0.7	1.1	1.0	0.7	1.0	0.1	0.6	-0.6	1.0	-0.2	1.2	-1.5	-0.9
Neuroticism score	1.1	2.2	5.2	1.8	-1.1	-1.8	-1.5	-1.2	0.8	1.0	-1.4	-0.7	-2.3	1.0	-2.1	1.8	1.4
Weight	1.8	8.7	18.8	-3.3	1.8	2.0	3.1	2.4	-0.4	-3.7	2.9	3.1	2.6	-3.7	3.3	-2.7	-4.3
Impedance of arm (right)	0.4	1.9	7.3	-1.7	-0.3	0.7	0.6	1.9	-1.8	-1.2	0.1	1.9	2.7	0.9	-1.0	0.3	-1.1
Arm fat percentage (right)	1.9	7.4	19.4	-3.0	0.9	0.8	2.3	1.8	-1.5	-4.4	2.2	3.6	2.1	-3.6	2.8	-0.9	-4.4
Trunk fat-free mass	0.7	3.8	9.4	-1.9	2.2	1.9	2.4	1.8	2.2	-1.2	1.6	0.8	0.2	-2.6	1.4	-3.1	-2.0
Hip circumference	2.1	8.9	17.8	-3.0	2.2	2.1	3.3	2.4	-1.6	-3.6	3.2	3.9	2.4	-3.8	2.7	-2.2	-4.2
Time employed in main current job	1.4	1.6	4.3	2.1	-1.0	-1.2	-0.9	-0.7	0.5	0.7	-1.2	-0.3	-1.8	0.3	-1.7	1.8	1.3
Alcohol intake versus 10 years previously	1.0	1.5	5.9	-1.1	-0.6	-1.2	0.5	1.0	0.3	-1.5	0.5	1.1	2.0	-2.4	-0.8	0.5	-1.4
Father’s age at death	0.8	1.1	8.9	-0.5	-0.4	-0.3	-0.4	-0.1	3.0	-0.9	-0.6	-0.8	0.0	-0.1	2.0	-0.4	-0.4
Worrier / anxious feelings	0.8	1.4	8.5	0.8	-0.3	-1.0	-0.6	0.1	2.1	-0.2	-2.0	-0.7	-2.9	-0.3	-0.3	0.4	0.1
Frequency of tiredness / lethargy in last 2 weeks	1.1	1.8	8.1	0.7	-1.4	-2.2	-1.6	-1.5	-0.6	-0.3	-0.5	0.3	-1.3	0.8	-0.4	2.8	0.9
Falls in the last year	0.5	0.6	2.6	0.1	-1.6	-0.9	-1.0	-0.5	0.1	-0.3	-0.0	0.2	-0.3	0.7	1.6	0.9	0.4
Hair/balding pattern: Pattern 3	0.1	0.2	0.9	0.3	0.5	0.4	0.5	-0.0	-0.2	-0.8	-0.1	0.1	0.1	-0.6	0.2	0.4	-1.0
Number of live births	0.4	0.6	2.3	1.2	0.3	0.0	-0.2	-1.1	-1.0	1.5	-0.2	-0.6	0.1	-0.1	-0.9	0.3	1.1
Forced expiratory volume in 1-second (FEV1)	0.5	1.6	4.3	-0.5	0.5	1.8	1.3	1.7	-0.9	-0.7	1.2	0.8	2.1	0.5	1.4	-1.6	-1.3
Pulse rate	0.4	0.8	3.5	0.9	-0.9	-0.7	-0.4	-0.8	-1.7	-0.5	0.4	0.7	1.9	0.3	-0.1	0.6	0.3
Happiness	0.5	0.6	4.4	0.6	-0.2	0.0	0.1	0.2	-2.1	-0.4	-0.1	0.9	1.3	0.4	-0.5	0.1	-0.5
Noisy workplace	0.4	0.5	1.3	-1.1	-0.6	-1.0	-0.1	0.1	0.0	-1.1	0.1	1.1	-0.2	-0.6	0.3	0.9	-0.9
Qualifications: A levels/AS levels or equivalent	0.9	2.1	7.7	1.4	1.0	1.1	-0.2	0.6	-1.0	2.8	-0.3	-2.1	-0.6	1.7	-1.4	-1.2	2.1
Serious illness, injury or assault of a close relative in last 2 years	0.9	1.0	1.7	1.2	-0.7	-1.1	-1.0	-1.2	0.6	0.8	-1.3	0.7	-0.9	1.2	-0.7	1.1	0.9
Mouth/teeth dental problems: Dentures	0.9	1.5	5.0	2.2	-1.5	-1.2	-1.4	-1.0	0.4	1.0	-1.9	-0.9	-0.1	0.3	-0.5	1.4	1.1
Asthma	2.0	3.9	10.6	2.4	-1.9	-2.4	-2.5	-3.3	-1.8	0.9	-1.1	-0.9	-1.5	1.1	-0.1	3.0	2.1
Medication: Ibuprofen (e.g. Nurofen)	0.5	0.7	1.7	0.9	-0.9	-1.0	-1.0	-1.2	-0.4	0.3	-0.7	-0.1	-1.0	1.3	-0.1	0.8	0.6
Medication: Cholesterol lowering	1.6	2.5	4.0	-1.9	1.5	1.2	1.7	1.0	-1.1	-1.2	1.6	1.0	1.8	-1.9	2.0	-1.8	-2.0
Depression (self-reported)	0.6	0.7	2.2	-0.7	0.3	-0.3	0.8	1.5	0.1	-0.9	-0.1	0.4	1.4	-1.1	-1.2	-0.4	-0.7
Medication: Lansoprazole	1.0	1.2	3.4	0.5	-1.7	-1.9	-1.3	-0.9	-0.2	-1.2	-1.3	-0.7	-0.4	-0.1	1.6	1.0	-0.4
Prospective memory result	0.5	0.6	2.8	-1.1	-0.1	-0.6	0.1	0.1	1.7	-0.8	-0.3	0.5	-0.3	-1.5	0.5	0.4	-0.6
Lung cancer (father)	0.7	0.8	2.4	1.6	-0.6	-0.3	-0.8	-1.0	-0.5	1.4	-0.1	-1.1	-0.6	1.1	0.6	0.3	1.1
Illnesses of mother	0.5	0.7	3.8	-0.2	1.0	0.7	0.8	0.7	-1.9	0.7	0.2	-0.5	0.4	-0.3	-0.2	-1.2	-0.3
Forced expiratory volume in 1-second (FEV1), Best measure	0.6	2.0	4.5	-1.1	0.5	1.6	1.7	2.1	-0.2	-1.6	1.6	1.2	1.7	-0.2	1.4	-1.5	-2.0
Pulse wave Arterial Stiffness index	1.4	1.6	5.4	-1.5	0.3	0.4	1.5	2.3	0.6	-1.4	0.7	1.3	0.9	-1.2	0.2	-0.8	-2.3
Impedance of arm (left)	0.5	2.4	12.4	-1.7	-0.4	0.7	0.8	1.9	-1.9	-1.6	0.5	2.0	3.5	0.8	-0.4	0.2	-1.4
Arm fat mass (right)	2.0	8.1	20.1	-3.1	1.5	1.4	2.8	2.1	-0.6	-4.1	2.6	3.2	2.1	-3.9	3.2	-1.9	-4.5
Trunk predicted mass	0.7	3.8	9.1	-2.0	2.2	1.8	2.4	1.8	2.2	-1.3	1.6	0.9	0.2	-2.7	1.3	-3.0	-2.1
Standing height	1.0	10.3	18.3	-4.0	2.7	3.5	3.9	4.3	1.4	-2.4	2.5	2.8	3.8	-2.4	1.0	-4.3	-3.6
Length of working week for main job	0.5	0.6	1.5	-0.9	0.3	0.1	0.6	0.6	0.6	-0.8	1.2	0.4	0.0	-0.7	1.1	-1.0	-1.0
Exposure to tobacco smoke at home	0.3	0.3	1.4	0.4	-0.7	-1.2	-0.6	-0.4	0.2	-0.7	-0.4	0.2	-0.6	-0.2	-0.2	1.0	0.1
Breastfed as a baby	0.4	0.5	4.4	0.0	0.2	0.4	0.3	0.2	2.1	0.0	-0.4	-0.1	0.6	-0.9	0.3	-1.1	-0.4
Tense / ‘highly strung’	2.5	4.1	11.9	2.0	-0.1	-1.1	-1.8	-2.2	-1.4	1.9	-1.5	-1.4	-2.4	1.9	-3.5	2.8	2.3
Seen doctor (GP) for nerves, anxiety, tension or depression	0.4	0.7	3.1	-0.6	-0.1	0.2	0.5	0.7	0.0	-0.3	1.7	1.8	1.4	0.2	-0.6	-0.3	-0.0
Hair/balding pattern: Pattern 4	0.3	0.7	3.0	0.1	0.4	1.0	-0.3	-0.4	-1.1	1.7	0.1	-0.3	0.9	0.3	0.4	-1.2	1.1
Birth weight of first child	0.4	0.7	2.8	0.0	-0.3	1.7	0.1	1.0	-0.2	0.0	-0.4	0.2	1.6	0.8	1.2	-1.0	-0.2
Peak expiratory flow (PEF)	0.6	1.4	5.9	-0.6	-0.9	0.1	0.3	1.0	-1.2	-1.6	0.7	1.2	2.0	-0.0	2.4	-0.8	-1.1
Pulse wave reflection index	0.2	0.2	1.2	-0.3	-1.1	-0.6	-0.2	0.5	0.1	0.1	-0.4	0.1	-0.5	0.4	0.5	0.4	-0.2
Ever highly irritable/argumentative for 2 days	0.2	0.3	1.3	-0.4	0.3	-0.3	-0.1	0.2	-1.1	0.4	-0.8	0.3	-0.1	0.0	-0.7	0.8	0.1
Loud music exposure frequency	1.0	1.1	4.4	1.3	0.2	0.7	-0.1	0.2	-1.4	1.7	-0.7	0.2	0.6	2.1	-1.4	-0.2	1.1
Qualifications: O levels/GCSEs or equivalent	0.6	0.9	4.0	-0.1	0.8	0.4	-0.1	0.5	0.4	1.1	-1.0	-0.9	-1.4	1.2	-2.0	-0.8	0.8
Mouth/teeth dental problems: Bleeding gums	0.9	1.2	3.3	0.6	-0.6	-1.2	-1.1	-0.5	-0.7	0.9	-0.5	-0.8	-1.3	0.5	-1.8	1.8	1.3
Blood clot in the leg (DVT)	0.7	0.9	2.3	1.3	-0.3	-0.0	-0.9	-1.1	-0.4	1.3	-0.7	-1.0	-0.4	1.5	0.0	0.7	1.4
Medication: Paracetamol	1.0	1.7	3.4	1.8	-1.8	-1.6	-1.7	-1.7	0.1	0.4	-1.1	0.2	-1.3	1.3	-0.1	1.6	1.3
Headache pain in last month	3.1	5.3	14.8	1.2	-3.1	-3.9	-2.4	-1.0	1.1	-0.5	-3.6	-0.9	-2.4	1.0	-2.9	3.4	0.9
Medication for cholesterol, blood pressure or diabetes	0.3	0.5	3.9	0.6	-0.6	-0.2	-0.3	0.4	0.4	0.1	-0.3	-0.5	0.1	0.8	-2.0	0.5	1.0
Glaucoma (self-reported)	1.3	1.5	5.4	-0.0	1.6	2.3	1.5	0.8	-0.8	0.9	1.7	0.1	1.6	0.1	0.3	-1.7	-0.2
Gout (self-reported)	0.9	1.2	4.0	-1.1	1.1	0.2	1.5	1.2	0.4	-0.8	0.7	1.2	0.3	-1.6	-2.0	0.4	-1.3
Hypothyroidism/myxoedema (self-reported)	0.8	1.5	5.8	0.3	-1.2	-1.5	-1.2	-0.8	-1.0	0.2	-1.6	-0.4	-1.1	0.4	-2.4	1.8	0.8
Medication: Amlodipine	1.0	1.5	4.5	0.6	-1.3	-1.1	-1.6	-1.2	-0.4	0.8	-2.1	-0.2	-1.0	1.7	-0.6	1.4	1.2
Medication: Ventolin 100micrograms inhaler	0.5	0.6	2.6	-0.8	0.3	-0.4	0.2	-0.5	-1.6	0.2	0.3	1.1	0.3	-0.4	-1.3	1.2	0.2
Birth weight	0.8	1.7	6.0	-1.1	0.7	1.1	1.3	1.8	-0.1	-2.4	0.7	1.1	1.6	-0.9	0.0	-1.4	-1.9
Chronic bronchitis/emphysema (mother)	1.0	1.2	3.4	0.5	-0.1	-0.3	-0.9	-1.6	1.1	1.9	-0.9	-1.2	-1.8	0.2	-0.8	0.6	1.3
High blood pressure (siblings)	1.0	1.5	3.9	0.9	-1.9	-1.8	-1.7	-1.0	-0.4	0.1	-1.7	0.3	-0.4	0.8	-0.6	2.0	1.1
Forced vital capacity (FVC), Best measure	1.0	3.5	7.2	-1.5	2.0	2.7	2.5	2.7	-0.2	-1.1	1.8	1.1	1.7	-0.7	1.2	-2.6	-2.2
Body fat percentage	2.1	8.4	22.1	-3.0	0.6	0.9	2.1	1.5	-1.8	-4.7	2.6	3.7	3.0	-3.1	3.9	-1.0	-4.6
Leg fat percentage (right)	1.0	3.5	10.2	-1.6	0.1	0.1	1.1	0.4	-1.3	-3.2	1.8	2.5	1.4	-2.2	3.0	-0.4	-2.9
Arm fat-free mass (right)	0.7	3.8	7.7	-1.7	1.6	1.5	2.2	1.6	1.5	-1.9	1.9	1.2	0.8	-2.8	2.2	-2.8	-2.5
Exposure to tobacco smoke outside home	1.0	1.3	5.9	1.1	-1.4	-1.9	-1.2	-0.8	0.0	-0.4	-1.4	-0.3	-2.4	0.6	-0.3	1.2	-0.0
Comparative body size at age 10	1.2	3.4	8.6	-0.8	1.2	1.2	2.0	1.3	2.5	-1.6	0.9	0.8	0.6	-2.2	2.7	-2.9	-2.5
Number of full brothers	0.4	0.5	2.2	-0.8	-0.3	-0.3	0.4	1.4	0.1	-1.5	-0.2	0.5	0.4	-0.0	0.1	0.1	-0.9
Worry too long after embarrassment	0.4	0.7	2.5	1.0	0.4	0.4	-0.2	-0.6	0.2	1.2	0.0	-1.2	-1.1	1.6	-1.0	-0.2	0.8
Seen a psychiatrist for nerves, anxiety, tension or depression	0.6	0.8	2.8	-1.1	0.5	0.3	1.0	1.0	0.5	-0.4	1.7	1.2	1.3	-0.8	-0.8	-0.1	-0.3
Wheeze or whistling in the chest in last year	0.6	1.1	2.4	-0.6	-0.6	-1.4	-0.5	-1.5	0.1	-1.3	0.3	1.3	-0.3	-1.6	1.5	1.5	-0.5
Number of children fathered	0.4	0.4	0.9	-0.8	-0.1	-0.5	0.0	0.9	0.7	-1.0	-0.3	-0.8	-0.9	-0.5	-0.6	0.2	-0.7
Reason for reducing amount of alcohol drunk: Health precaution	3.0	3.5	7.3	-1.7	2.0	2.6	2.2	2.7	-0.8	-0.5	2.7	1.6	1.5	-1.0	1.1	-2.5	-1.3
Age at first live birth	1.4	2.6	8.0	-1.1	2.0	2.8	1.7	1.8	-1.4	1.0	2.1	-0.0	1.6	0.8	0.5	-2.4	-0.3
Pulse wave peak to peak time	1.0	1.1	4.1	1.2	-0.1	-0.2	-1.3	-2.0	-0.8	1.1	-0.3	-1.2	-0.6	1.0	-0.0	0.6	1.9
Health satisfaction	1.1	1.5	10.7	1.4	0.8	1.0	0.1	-0.6	-3.3	1.0	1.9	0.1	-0.0	0.7	-0.4	0.7	0.4
Shortness of breath walking on level ground	0.4	0.5	3.0	-0.1	0.4	0.6	0.3	0.3	-1.3	0.5	1.7	0.5	0.5	-0.1	0.4	0.1	0.2
Qualifications: College or University degree	0.6	2.0	7.9	1.0	1.0	2.0	0.5	0.4	-2.3	2.0	1.4	-0.2	0.5	2.8	-0.3	-1.2	1.0
Eye problems/disorders: None of the above	0.3	0.4	1.1	0.9	-0.0	-0.2	-0.3	-0.0	-0.4	0.5	-0.0	-0.8	-0.7	1.0	-0.8	0.7	0.5
Mouth/teeth dental problems: Loose teeth	0.2	0.3	0.8	-0.3	-0.1	-0.7	-0.3	-0.3	-0.6	-0.2	-0.9	0.8	0.0	-0.6	-0.8	0.4	0.1
Emphysema/chronic bronchitis	0.5	0.6	3.6	-0.1	-0.6	-0.8	0.1	-0.1	0.5	-1.1	0.1	1.9	0.2	-0.8	0.0	0.5	-0.9
Medication for pain relief, constipation, heartburn	1.0	1.8	6.2	-0.6	1.5	2.5	1.4	1.7	-0.2	1.0	1.2	-0.1	2.2	-0.0	0.3	-2.0	0.0
Neck or shoulder pain in last month	2.3	3.2	8.3	1.3	-1.9	-2.6	-2.1	-1.1	0.3	-0.5	-2.7	-0.6	-2.8	0.9	-1.1	2.9	0.8
Medication: Blood pressure	0.4	0.6	2.9	-0.6	0.8	0.2	0.1	-0.6	1.0	0.2	-0.1	0.2	-1.4	-0.9	1.7	-0.2	-0.7
Angina (self-reported)	1.1	1.5	3.6	-0.5	1.7	1.2	1.8	1.7	-0.3	-0.9	1.5	0.4	-0.0	-1.2	0.1	-1.3	-1.9
Migraine (self-reported)	0.5	0.6	1.7	0.7	-1.3	-0.8	0.1	0.8	0.8	-1.2	-1.0	-0.2	1.0	0.2	0.7	-0.3	-1.0
Medication: Ibuprofen	0.1	0.2	0.8	0.5	0.0	0.0	-0.2	-0.5	-0.5	0.3	-0.1	0.1	-0.9	0.8	-0.3	0.2	0.3
Medication: Allopurinol	2.1	2.8	6.4	-2.2	1.3	0.2	1.9	2.1	1.5	-1.2	0.5	2.2	-0.4	-2.5	-2.4	0.4	-1.7
Medication: Omeprazole	1.1	1.3	3.7	1.4	-1.4	-1.5	-1.4	-0.8	0.5	0.2	-1.9	-0.9	-1.0	0.8	0.1	1.4	0.8
Medication: Seretide 50 evohaler	1.0	1.1	7.7	0.6	-0.4	0.3	-0.0	-0.5	-2.8	0.8	1.6	0.3	1.4	1.0	0.7	0.4	0.6
Mean time to correctly identify matches	1.1	2.1	8.9	1.0	2.1	1.6	0.5	-0.6	1.2	3.0	-0.3	-2.1	-1.8	0.2	-0.5	-1.0	1.3
Heart disease (mother)	0.5	0.6	3.0	-0.4	-0.4	0.1	0.5	1.3	0.5	-1.7	0.2	0.5	0.9	-0.6	0.2	-0.1	-1.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.7	0.9	2.8	-0.8	1.7	1.7	1.0	0.8	0.2	0.1	-0.3	0.8	-0.1	0.6	-0.5	-1.5	-0.5
Whole body fat mass	2.3	9.5	24.3	-3.3	1.2	1.4	2.7	2.0	-0.9	-4.7	2.8	3.6	2.7	-3.6	3.9	-1.8	-4.9
Leg fat mass (right)	1.4	5.4	13.4	-2.4	0.9	0.9	2.0	1.1	-0.3	-3.5	2.3	2.6	1.7	-3.0	3.4	-1.5	-3.7
Arm predicted mass (right)	0.9	4.6	9.2	-1.9	1.9	1.7	2.5	1.9	1.6	-2.1	2.2	1.4	1.1	-2.9	2.2	-3.0	-2.8
Pulse rate, automated reading	0.8	2.6	9.4	1.0	-2.3	-2.5	-2.4	-3.1	-1.1	-0.5	-0.9	0.2	0.3	0.1	0.6	2.1	1.4
Alcohol intake frequency.	1.7	3.9	12.6	-1.2	-1.3	-1.8	1.1	2.1	2.2	-3.5	0.4	2.2	2.0	-3.2	0.7	0.2	-2.4
Comparative height size at age 10	0.3	1.6	6.0	-1.9	-0.9	-0.5	0.3	0.7	0.6	-1.7	0.5	1.9	2.4	-1.5	-0.7	-0.1	-0.8
Number of full sisters	2.7	3.3	9.6	1.3	-2.9	-2.8	-2.3	-2.3	-1.6	-0.2	-1.1	0.1	0.0	1.6	-0.5	3.1	0.7
Suffer from ‘nerves’	1.5	2.4	9.4	2.2	-0.1	-0.3	-1.0	-1.1	-0.1	3.1	-1.2	-1.4	-0.9	1.8	-1.7	0.9	2.6
Overall health rating	0.4	0.9	3.8	0.3	-0.4	-1.4	-0.4	-0.8	-0.3	-1.0	0.3	0.4	-1.4	-1.6	-0.2	1.9	-0.7
Chest pain or discomfort	0.9	1.3	4.3	0.5	0.1	-1.0	-0.8	-1.6	-0.5	1.1	-0.8	-0.0	-1.6	0.2	-2.1	2.0	0.8
Had major operations	0.8	1.0	6.4	-2.5	0.6	0.1	0.8	0.5	-0.3	-1.1	0.9	0.7	1.0	-0.9	0.6	-0.4	-1.1
Age at last live birth	0.8	1.2	3.0	-0.7	1.0	1.7	0.9	0.9	-1.4	1.2	1.4	0.4	1.1	1.3	-0.5	-1.4	0.1
Family relationship satisfaction	0.6	0.7	2.1	-1.1	0.5	-0.0	0.7	0.7	-1.0	-0.9	0.2	1.5	0.6	-1.1	-0.7	-0.2	-1.1
Leg pain on walking	0.6	0.8	3.1	-0.5	-0.9	-0.4	-0.0	1.0	0.4	-1.8	0.4	1.1	-0.6	-0.0	-0.9	1.6	-0.8
Qualifications: NVQ or HND or HNC or equivalent	0.7	0.8	3.9	0.4	0.3	-0.1	-0.5	-0.9	0.2	2.0	-0.7	-0.6	-0.8	1.1	-1.5	-0.1	1.3
Commuting to job workplace: Car/motor vehicle	0.3	0.3	1.2	-0.1	0.6	0.4	0.7	1.1	0.0	-0.2	0.7	0.8	-0.3	-0.5	-0.4	-0.3	-0.5
Illness, injury, bereavement, stress in last 2 years	0.5	0.6	2.1	0.7	1.1	1.2	0.5	0.6	-1.2	0.6	0.0	-0.6	0.5	-0.2	-0.4	-1.5	0.4
Medication: Aspirin	2.0	2.7	6.5	-2.3	1.6	1.0	2.0	1.6	1.0	-2.0	1.2	1.0	0.5	-2.5	0.4	-1.5	-2.3
Supplements: Vitamin C	0.5	0.6	3.1	-0.2	-0.6	-0.7	-0.4	-0.4	-0.6	-0.8	-1.7	1.4	0.6	-0.4	-0.3	0.5	-0.1
Knee pain experienced in last month	1.1	1.7	3.4	1.8	-1.8	-1.1	-1.6	-1.4	-1.4	0.1	-0.8	-1.3	-0.7	1.6	0.2	1.7	0.7
Hypertension (Self-reported)	0.3	0.8	3.6	0.1	0.6	-0.1	0.1	-0.7	0.5	0.3	-1.1	-0.3	-1.9	-1.8	0.6	-0.3	-0.9
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.4	0.4	1.7	0.1	-0.0	-0.6	0.1	-0.5	1.3	-0.6	-0.9	0.2	-0.5	-1.0	0.9	0.5	-0.8
Illnesses of father: Heart disease	1.5	2.1	6.6	-1.7	0.9	1.4	1.7	2.3	-0.1	-1.5	1.3	2.6	0.8	-0.8	-1.0	-0.6	-1.5
Illnesses of siblings: Diabetes	1.4	1.7	7.2	0.1	-2.4	-2.7	-1.5	-0.4	0.2	-1.6	-1.5	-0.1	-0.4	-0.9	-0.2	1.8	0.2
Smoking status: Previous	0.5	0.7	2.7	-0.8	-0.8	-1.3	-0.3	0.2	-0.7	-1.6	-0.3	0.3	0.1	-1.0	0.1	1.3	-0.9
Forced expiratory volume in 1-second (FEV1), predicted	2.0	4.2	15.4	-2.3	1.5	2.1	2.9	3.9	1.4	-1.5	1.3	1.3	1.4	-1.2	-0.4	-2.2	-2.6
Whole body fat-free mass	0.9	5.0	9.8	-2.4	2.2	2.0	2.8	2.2	1.6	-1.9	2.0	1.5	0.9	-3.0	1.7	-3.1	-2.8
Leg fat-free mass (right)	1.5	8.0	15.4	-3.3	2.2	2.3	3.5	3.2	0.8	-3.0	2.5	2.6	2.2	-3.5	1.9	-3.2	-3.9
Arm fat percentage (left)	1.9	7.7	19.5	-2.8	0.9	0.9	2.4	1.8	-1.6	-4.4	2.5	3.5	2.5	-3.5	3.1	-1.1	-4.4
Average weekly red wine intake	0.6	0.8	3.5	-0.5	1.2	1.6	1.0	0.9	0.7	0.6	0.2	-0.1	-0.6	0.3	0.4	-1.9	-0.6
Handedness (chirality/laterality): Left-handed	0.4	0.5	4.3	0.2	-0.3	-0.1	-0.3	-1.1	0.0	0.1	-0.6	-0.1	-0.3	-0.1	2.1	-0.9	0.0
Mood swings	1.6	2.8	10.1	0.8	-2.2	-3.2	-2.1	-2.0	-0.4	-0.3	-0.8	0.8	-1.6	-0.5	-0.8	3.2	0.8
Loneliness, isolation	0.7	1.0	3.6	1.8	-0.7	-0.8	-0.6	-0.1	0.4	0.3	-1.0	-0.5	-1.9	0.5	-1.1	1.6	0.3
Long-standing illness, disability or infirmity	0.4	0.6	4.0	-0.3	0.0	-0.3	-0.6	-1.0	0.1	-0.1	0.5	-0.6	-0.9	-0.9	2.0	0.3	-0.1
Ever had bowel cancer screening	0.3	0.4	1.9	0.4	0.9	0.7	0.2	0.3	0.2	0.4	-0.8	-0.7	-0.5	-0.3	0.3	-1.4	-0.4
Diabetes diagnosed by doctor	0.4	0.7	2.6	0.0	-1.2	-1.6	-0.9	-1.0	-0.7	-0.9	-0.3	0.4	-0.0	-1.2	0.3	0.9	-0.2
Ever had stillbirth, spontaneous miscarriage or termination	0.5	0.5	2.1	-0.1	0.2	0.5	-0.2	0.5	0.1	1.0	-0.0	-0.5	-0.6	1.2	-1.4	0.4	1.0
Friendships satisfaction	0.4	0.5	2.3	1.0	-0.7	-0.3	-0.6	-0.8	-1.5	0.4	0.3	-0.1	1.0	0.8	0.3	0.1	0.6
Qualifications: nursing, teaching	0.4	0.6	2.7	0.5	0.4	0.6	0.3	0.3	-0.2	1.5	0.3	-0.8	-0.1	0.7	-1.7	-0.6	0.6
Commuting to job workplace: Walk	0.4	0.4	1.3	-0.5	-0.0	-0.7	-0.4	-0.9	-0.8	-0.2	-0.8	-0.2	-0.2	-0.6	-1.0	1.1	0.1
Eye problems/disorders: Cataract	0.2	0.2	2.4	-0.1	-0.2	-0.3	-0.3	-0.1	0.1	-0.2	-1.5	0.4	-0.3	-0.1	0.5	0.1	-0.1
Mouth/teeth dental problems: Mouth ulcers	1.6	2.6	11.9	1.1	-0.9	-0.9	-1.4	-0.0	-1.2	0.9	-1.6	-0.9	-1.4	2.5	-3.5	1.6	1.7
Medication for cholesterol	0.7	1.1	4.4	1.0	0.6	1.0	-0.2	-0.3	0.2	1.5	0.2	-1.1	0.2	2.1	1.8	-1.0	1.0
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.2	1.5	5.2	-1.4	-0.1	-1.1	0.2	-0.3	1.8	-2.0	0.2	0.5	-0.4	-2.3	1.2	-0.2	-1.7
Back pain experienced in last month	0.4	0.6	1.7	-1.3	0.8	0.6	1.0	0.7	1.3	-0.4	0.1	1.0	0.0	-0.8	-0.4	-0.5	-0.9
Mineral and other dietary supplements	0.9	1.3	4.2	-1.9	-0.1	-0.6	0.9	0.5	-0.5	-1.3	0.8	1.2	1.8	-2.1	-0.4	0.3	-1.0
Breast cancer (self-reported)	0.3	0.3	1.0	0.1	0.8	0.9	0.5	-0.1	0.4	0.6	1.0	0.4	0.5	0.2	0.5	-0.7	0.0
Asthma (self-reported)	1.8	3.6	9.3	2.2	-1.8	-2.3	-2.4	-3.0	-1.9	1.0	-1.2	-0.9	-1.3	0.9	-0.3	3.0	2.0
Osteoporosis (self-reported)	0.3	0.4	0.7	0.6	-0.8	-0.7	-0.8	-0.1	-0.1	0.4	-0.3	-0.8	-0.7	0.7	0.4	0.7	0.5
Osteoarthritis (self-reported)	0.5	0.6	2.2	0.3	-0.9	-0.4	-1.0	-1.5	-0.8	-0.3	0.7	-0.2	1.4	0.1	0.9	0.1	0.7
Medication: Aspirin	1.6	2.1	6.6	-2.0	1.5	0.7	1.7	0.9	0.6	-1.9	1.1	0.8	0.6	-2.6	0.4	-1.1	-2.1
Medication: Gliclazide	1.0	1.2	4.2	-0.6	1.2	1.4	1.3	0.9	0.0	0.1	0.9	0.6	0.5	-0.8	1.4	-2.1	-1.3
Illnesses of father: None of the above (group 1)	1.3	1.6	5.7	1.7	-0.6	-0.3	-1.0	-1.5	0.5	1.7	-0.0	-2.0	-0.5	1.0	2.4	-0.7	1.1
Smoking status: Current	0.2	0.3	1.3	0.1	0.1	-0.4	-0.4	-0.3	1.1	0.1	-0.7	-0.2	-1.1	-0.7	0.0	0.3	0.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.1	0.3	1.1	-0.2	-0.5	0.1	-0.0	1.0	0.2	-0.8	-0.1	0.3	-0.6	1.1	-0.0	0.3	-0.5
Whole body water mass	1.0	5.4	10.6	-2.5	2.3	2.1	2.9	2.4	1.6	-1.9	2.1	1.6	1.0	-3.0	1.7	-3.2	-2.9
Leg predicted mass (right)	1.6	8.3	15.8	-3.4	2.3	2.4	3.5	3.2	0.9	-3.0	2.5	2.6	2.2	-3.6	1.9	-3.3	-4.0
Arm fat mass (left)	2.0	8.1	20.2	-3.1	1.4	1.3	2.8	1.9	-0.6	-4.2	2.6	3.3	2.0	-3.9	3.2	-1.8	-4.5
Number of self-reported non-cancer illnesses	0.2	0.4	2.5	-0.4	0.5	-0.6	0.1	-0.2	-0.6	-0.3	-0.6	0.1	-0.7	-1.6	0.2	0.2	-0.8
Average weekly champagne plus white wine intake	1.6	2.3	4.6	-1.4	1.0	2.1	2.0	2.1	-0.1	-1.1	1.9	1.4	1.8	-0.5	0.9	-1.5	-1.6
Miserableness	0.7	1.3	5.0	-0.3	-1.1	-1.6	-0.6	-0.1	0.7	-0.8	0.2	1.6	-0.9	-0.6	-1.8	2.2	0.1
Guilty feelings	1.2	1.8	4.5	1.8	-0.0	-0.1	-1.0	-1.7	-0.4	2.1	0.2	-0.8	-1.6	2.1	-1.0	0.9	1.7
Wears glasses or contact lenses	0.2	0.2	1.2	-0.4	0.3	0.3	0.3	0.3	-1.1	-0.4	-0.0	-0.0	0.0	-0.2	0.1	0.5	-0.6
Ever taken oral contraceptive pill	0.1	0.1	0.7	-0.5	0.2	-0.1	0.1	0.1	-0.8	-0.2	0.2	0.5	0.4	0.2	-0.1	0.1	-0.4
Hearing aid user	1.0	1.1	3.4	-0.3	-0.7	0.0	-0.1	1.8	-1.2	0.2	-1.1	0.6	0.9	1.7	-1.5	1.5	0.4
Mother’s age at death	0.5	0.6	4.2	0.1	0.3	0.9	0.2	0.5	2.1	-0.1	-1.0	-0.6	-0.7	0.2	0.1	-0.6	-0.6
Financial situation satisfaction	1.5	1.8	4.6	-2.1	1.1	1.4	1.7	2.1	-1.1	-0.8	0.6	1.6	0.6	0.3	0.4	-0.7	-2.0
Tinnitus: Yes, now most or all of the time	0.8	0.9	2.2	-0.0	-1.3	-1.5	-1.0	-1.2	-0.6	-1.1	-0.2	1.2	0.9	-0.1	1.0	1.2	0.3
Commuting to job workplace: Public transport	0.8	0.9	2.7	0.6	-1.3	-1.0	-1.3	-1.6	-0.2	0.2	-0.4	-1.0	-0.4	0.3	1.6	1.0	0.6
Eye problems/disorders: Glaucoma	1.0	1.1	4.6	0.1	1.4	2.1	1.1	0.6	-0.7	1.5	1.3	-0.3	1.2	-0.0	-0.5	-1.2	0.3
Medication: Blood pressure	0.2	0.3	1.4	0.6	0.3	0.2	0.1	-0.2	0.1	0.1	-1.0	-0.5	-1.2	-0.9	0.1	-0.5	-0.3
Pain type(s) experienced in last month: Hip pain	0.7	0.9	2.2	0.5	-0.8	-0.5	-1.3	-1.2	-0.7	1.3	0.3	-0.3	-1.0	1.4	0.5	0.9	1.5
Supplements: Fish oil (including cod liver oil)	0.9	1.2	2.9	1.7	1.2	1.6	0.1	0.0	0.3	1.4	-0.4	-1.5	-1.4	1.0	0.6	-1.3	0.6
High cholesterol (Self-reported)	1.1	2.0	7.5	-2.7	0.8	0.5	1.3	1.2	-0.3	-1.6	-0.1	1.8	1.4	-1.7	0.2	-1.3	-2.0
Medication: Bendroflumethiazide	0.4	0.6	3.3	-0.5	-0.6	-0.5	0.0	-0.4	-0.2	-1.8	0.4	0.7	0.5	-0.9	0.3	0.3	-1.5
Medication: Paracetamol	0.3	0.5	2.1	0.6	-0.4	-0.6	-0.3	-0.8	1.0	0.2	-0.5	0.7	-1.5	0.1	-0.5	0.7	0.5
Medication: Lisinopril	0.5	0.7	4.8	0.1	0.5	-0.4	0.4	-0.6	-1.6	0.1	-0.6	-0.2	0.7	-2.2	0.4	-0.0	-0.5
Medication: Atorvastatin	0.9	1.1	3.8	-1.2	-1.5	-1.9	-0.9	0.1	-0.0	-1.4	-1.3	0.8	0.8	-1.0	0.5	1.1	-0.4
Illnesses of father: High blood pressure	0.4	0.5	1.6	-1.1	0.5	0.2	0.9	1.3	0.3	-0.5	0.2	0.7	0.5	-0.7	-0.6	-0.1	-0.6
Alcohol drinker status: Never	0.7	0.9	4.4	0.7	-0.6	-0.8	-0.4	-0.3	1.8	-0.7	-2.1	-0.6	-1.1	-1.0	-0.1	0.3	-0.3
Ever smoked	0.6	1.1	3.1	0.4	-0.3	-1.3	-1.1	-0.7	-0.6	0.2	-0.5	-1.5	-1.6	0.4	-1.5	1.8	0.3
Basal metabolic rate	1.2	6.4	11.6	-2.9	2.2	2.0	3.0	2.5	1.2	-2.6	2.4	2.0	1.4	-3.4	2.1	-3.2	-3.4
Leg fat percentage (left)	1.2	4.4	12.7	-1.8	0.3	0.3	1.3	0.6	-1.4	-3.6	1.8	2.8	1.9	-2.5	3.3	-0.7	-3.2
Arm fat-free mass (left)	0.8	4.3	9.2	-2.3	1.9	1.4	2.4	1.8	1.7	-2.0	1.7	1.5	0.6	-3.0	1.7	-2.8	-2.6
Number of operations (self-reported)	0.3	0.5	2.2	-1.5	0.4	0.7	0.6	0.5	0.1	0.3	0.2	0.6	1.0	-1.0	0.4	-0.9	0.0
Average weekly beer plus cider intake	2.0	2.9	7.7	1.3	-1.9	-2.6	-2.4	-2.8	-0.8	0.9	-1.9	-0.9	-0.1	1.1	-0.0	2.2	1.6
Irritability	1.9	3.3	6.2	2.2	-1.1	-2.0	-2.3	-2.3	-0.6	1.3	-1.9	-1.7	-2.5	1.8	-1.0	1.9	1.6
Risk taking	0.9	1.3	4.8	0.1	-0.9	-0.8	-0.8	-0.8	-2.1	0.4	0.3	0.4	-0.4	1.6	-1.4	2.2	0.8
Ever had prostate specific antigen (PSA) test	0.7	0.8	6.2	-0.7	0.2	-0.0	0.5	0.9	2.5	-0.3	-1.1	0.1	-0.8	-0.8	-0.5	-0.3	0.0
Fractured/broken bones in last 5 years	0.5	0.6	2.2	-0.9	-0.6	0.4	-0.4	0.2	-0.6	0.1	0.9	1.2	1.5	0.7	0.6	-0.8	1.0
Age started oral contraceptive pill	1.2	1.5	5.1	2.2	-0.8	-0.3	-1.1	-1.2	-2.2	1.1	-0.7	-0.8	0.3	2.1	-0.4	0.2	0.7
Diastolic blood pressure, automated reading	1.1	3.3	14.7	-2.3	0.5	-0.2	1.6	0.9	1.1	-2.2	1.3	3.0	0.2	-3.8	0.4	-0.4	-2.1
Ever depressed for a whole week	0.2	0.2	1.1	-0.3	0.3	0.0	0.1	-0.1	-0.3	1.1	-0.7	0.1	0.6	0.2	-0.8	0.2	0.3
Unable to work because of sickness or disability	1.2	1.6	5.5	0.6	-1.1	-1.7	-1.6	-2.3	0.9	0.7	-0.3	-0.7	-1.0	-0.1	-0.2	1.6	1.9
Commuting to job workplace: Cycle	1.6	1.9	6.4	-1.2	0.2	1.0	1.6	2.5	0.4	-1.5	-0.3	1.0	2.3	-0.7	-0.9	-1.5	-1.7
Myopia	0.4	0.6	2.1	0.7	-0.2	-0.4	-0.6	-0.4	-0.1	0.4	-0.8	-1.0	-1.1	1.2	1.4	0.5	0.0
Vascular/heart problems diagnosed by doctor	0.5	1.4	7.8	1.1	-0.4	0.6	-0.5	0.0	-0.9	1.2	0.7	-0.4	1.4	2.8	-1.0	0.3	1.9
Cholesterol lowering medication	0.6	0.8	2.8	-1.1	0.2	0.3	0.7	0.6	-0.7	-1.1	-0.2	1.1	1.3	-1.7	-0.6	-0.8	-1.1
Medication: Omeprazole (e.g. Zanprol)	3.0	3.6	7.3	2.5	-2.4	-2.5	-2.3	-1.3	0.6	0.2	-2.7	-1.8	-1.9	1.9	-0.0	2.4	1.3
Pain experienced in last month	0.7	1.1	2.6	-0.4	1.3	1.4	1.0	0.4	-1.0	0.0	1.5	0.4	1.4	-0.1	1.6	-1.5	-0.3
Supplements: Calcium	0.3	0.3	1.0	0.9	-0.6	-0.4	-0.4	-0.2	0.8	0.7	-1.0	-0.2	-0.8	0.5	-0.1	0.1	0.4
Basal cell carcinoma (self-reported)	0.4	0.4	2.2	-0.3	0.7	0.7	0.5	1.0	-0.1	-0.7	0.1	-0.3	0.5	-0.7	-1.5	0.1	-0.2
Heart attack/myocardial infarction (self-reported)	2.8	3.6	7.2	-2.7	2.4	1.8	2.6	2.4	0.4	-1.5	2.2	1.4	0.7	-2.5	-0.4	-1.1	-2.3
Deep venous thrombosis (DVT) (self-reported)	0.8	1.0	3.1	1.5	-0.4	0.0	-1.0	-1.2	-0.7	1.4	-0.5	-1.1	-0.3	1.8	0.3	0.6	1.4
Heart disease (siblings)	0.6	0.7	2.0	0.6	-0.8	-1.2	-1.3	-0.9	-0.0	-0.2	-0.4	-0.5	-0.8	0.3	-1.1	1.4	0.7
Alcohol drinker status: Previous	2.1	2.4	6.8	-0.6	-0.9	-1.3	0.6	0.5	-1.6	-2.6	1.7	2.1	1.8	-2.0	1.4	0.9	-1.9
Pack years of smoking	0.7	1.1	4.8	0.3	-0.5	-1.1	-0.7	-0.7	2.2	-0.0	-0.9	-0.8	-1.5	-1.2	-1.0	1.0	0.5
Impedance of whole body	0.3	1.5	8.8	-0.9	-0.7	0.4	0.1	1.0	-2.0	-0.9	0.2	1.5	3.0	1.5	-0.3	0.5	-0.5
Leg fat mass (left)	1.5	6.0	14.4	-2.5	1.0	1.0	2.1	1.2	-0.5	-3.7	2.4	2.6	1.9	-3.2	3.6	-1.7	-3.8
Arm predicted mass (left)	0.8	4.3	9.2	-2.1	2.0	1.6	2.5	1.8	1.7	-1.9	1.8	1.3	0.6	-3.0	1.8	-2.9	-2.7