Hub : Genes

PAMR1

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.2260	0.0500	2.9e-06	0.072	0.060	0.130	0.121	0.140	3.9e-09	7.6e-08	1.7e-15	1.8e-14	1.1e-16
2	GTEx	Cells Transformed fibroblasts	0.2320	0.0570	2.5e-05	0.123	NA	0.114	NA	0.117	1.8e-09	NA	6.7e-09	NA	4.2e-09
3	GTEx	Skin Sun Exposed Lower leg	0.1070	0.0440	4.4e-03	0.018	NA	0.006	NA	0.014	1.2e-02	NA	9.2e-02	NA	2.3e-02
4	ROSMAP	Brain Pre-frontal Cortex	0.0931	0.0333	1.2e-03	0.047	0.008	0.039	0.040	0.045	9.2e-07	2.6e-02	7.9e-06	5.4e-06	1.5e-06
5	TCGA	Breast Invasive Carcinoma	0.0611	0.0205	1.3e-04	0.001	0.011	0.015	NA	0.017	2.3e-01	1.8e-03	4.2e-04	NA	1.4e-04
6	TCGA	Colon Adenocarcinoma	0.1060	0.0440	1.8e-03	0.002	0.048	0.001	NA	-0.002	2.4e-01	9.1e-04	2.7e-01	NA	4.4e-01
7	TCGA	Kidney Renal Clear Cell Carcinoma	0.0955	0.0322	4.3e-04	0.060	0.040	0.043	NA	0.057	2.5e-07	2.4e-05	1.2e-05	NA	5.1e-07
8	TCGA	Lung Squamous Cell Carcinoma	0.0592	0.0249	3.2e-03	0.001	0.026	0.022	NA	0.018	2.3e-01	4.9e-04	1.3e-03	NA	3.6e-03

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8
Bipolar Disorder (2018)	0.6	1.0	4.8	-0.3	1.4	0.4	-0.3	0.8	-0.5	-2.2	-0.5
Bipolar Disorder or Schizophrenia	0.9	2.2	10.4	-0.1	2.3	0.1	-0.5	0.8	-1.0	-3.2	-0.2
Depressed Affect (Nagel 2018)	0.8	1.8	4.1	-0.3	-1.6	-1.4	-0.7	-0.5	-1.1	1.9	-2.0
Depression (Nagel 2018)	0.5	0.7	2.6	-0.3	-0.3	-0.4	-1.0	0.9	0.5	0.9	-1.6
Intelligence (Savage-Jansen 2018)	0.8	2.5	5.0	2.0	-0.0	-0.8	2.1	2.2	2.1	0.8	-1.0
Neuroticism (Nagel 2018)	0.6	1.4	3.8	0.7	-1.3	-1.6	0.4	0.5	-0.3	1.5	-1.9
Schizophrenia (2018)	0.6	1.3	5.7	0.2	1.9	-0.2	-0.4	0.4	-0.8	-2.4	0.1
Schizophrenia vs Biploar Disorder	0.8	1.1	3.0	1.3	-1.2	-0.1	0.6	1.2	0.9	1.7	-0.0
Worry (Nagel 2018)	0.5	1.1	2.5	0.8	-0.9	-1.3	0.7	0.9	0.3	1.1	-1.6
Alzheimer’s Disease (in mother)	1.2	1.4	4.1	-1.2	-0.9	-0.8	-1.4	-1.4	-2.0	0.0	0.1
Alzheimer’s Disease (in father)	0.9	1.0	4.6	0.4	0.2	-1.3	0.6	2.1	-0.2	-1.0	-0.2
Alzheimer’s Disease (including proxy)	0.3	0.5	1.3	-0.7	0.3	-1.0	-0.7	0.2	-0.5	-1.1	0.4
Crohns Disease (2017)	1.0	2.1	5.4	-2.1	0.8	-1.3	-2.3	-0.2	-1.0	-1.5	1.2
Irritable Bowel Disease (IBD)	1.2	2.9	7.6	-2.5	0.9	-0.8	-2.8	-1.4	-1.9	-1.3	0.9
Ulcerative Colitis (UC)	1.3	2.4	6.4	-2.3	0.7	-0.1	-2.5	-1.8	-1.9	-0.5	0.3
Major Depression (MDD)	0.3	0.4	1.4	0.5	-0.1	-0.7	0.0	0.7	-0.5	-0.3	-1.2
Reaction Time	1.0	1.9	3.9	1.7	-1.6	-1.7	0.9	0.6	-0.1	-1.2	-2.0
Verbal and Numeric Reasoning (VNR)	0.7	1.6	4.0	2.0	1.5	0.6	1.7	1.5	0.6	-0.7	-0.4
Breast Cancer	3.0	7.2	17.2	-3.4	-2.3	-1.3	-2.6	-4.2	-3.5	0.6	-1.4
Ovarian Cancer	0.8	1.0	2.1	0.2	-0.3	-1.0	1.2	-0.5	-1.4	-1.0	1.5
Prostate Cancer	0.5	0.7	1.6	-0.9	-0.9	-1.3	-1.0	-1.0	0.6	0.6	0.0
Age at First Birth	0.3	0.4	1.4	0.6	-0.5	-1.2	0.2	-0.6	-0.3	0.5	-0.6
Bipolar Disorder (2011)	0.5	0.5	1.6	0.1	0.4	0.6	0.4	-1.2	-1.1	-0.5	-0.1
Body Mass Index (BMI) (2010)	1.2	1.7	5.5	-2.3	0.0	0.5	-2.4	-1.2	-0.3	0.5	0.6
Coronary Artery Disease (CAD)	0.9	1.1	3.0	0.2	1.7	1.0	0.8	1.1	-0.2	0.0	1.6
Crohns Disease (2012)	0.5	0.8	2.4	-1.1	0.0	-1.4	-1.5	0.8	-0.6	-0.1	0.3
Mean Putamen Volume	0.4	0.5	2.1	0.5	-0.3	-1.5	-0.2	-0.2	-0.3	-0.0	-1.1
Fasting Glucose	0.8	1.0	2.9	0.2	-1.7	0.3	0.6	1.6	0.4	1.2	-0.5
HbA1C	2.0	2.2	4.8	-2.1	-0.1	-2.2	-1.7	0.3	-1.8	0.2	1.4
HDL Cholesterol	0.7	1.1	5.9	0.7	0.3	0.1	0.6	2.4	-0.2	0.4	1.5
LDL Cholesterol	0.4	0.6	2.7	-0.2	-1.6	0.3	-0.4	-0.3	0.8	0.9	-0.6
Lupus	0.2	0.4	1.0	0.8	-0.4	0.2	1.0	0.6	-0.3	-0.1	0.7
Neuroticism (2016)	1.5	2.1	9.4	0.9	-1.1	-0.7	0.7	-0.3	0.7	2.0	-3.1
Primary Biliary Cirrhosis	0.1	0.2	0.4	-0.5	-0.5	-0.1	0.1	-0.6	-0.4	0.5	0.6
Rheumatoid Arthritis	0.2	0.3	0.7	-0.7	-0.0	0.6	-0.8	0.3	0.0	0.7	0.3
Schizophrenia (2014)	0.3	0.6	2.0	0.3	1.0	0.0	-0.2	1.0	-0.5	-1.4	0.3
Triglycerides	0.2	0.4	0.8	-0.9	0.6	-0.1	-0.9	-0.5	-0.3	-0.2	0.7
Type 2 Diabetes (T2D) (2012)	1.3	1.5	2.7	-1.4	1.2	-0.4	-1.6	-1.6	0.1	-0.9	1.6
Ulcerative Colitis	1.7	2.5	5.7	-2.3	1.1	0.6	-2.4	-1.7	-1.1	-1.3	1.1
Blood Eosinophil Count	0.1	0.9	2.3	0.5	-1.4	0.7	0.0	-1.4	-1.5	0.6	-0.5
Blood Platelet Count	0.2	2.6	7.2	-1.1	-2.7	-1.4	-1.3	-0.8	-0.5	2.6	-1.0
Blood Red Count	0.0	0.3	0.9	-0.1	-0.5	-0.3	0.4	-0.4	0.5	0.4	-1.0
Blood White Count	0.1	1.1	2.9	1.4	-0.8	-0.3	1.7	0.4	0.4	1.5	0.8
Heel T-Score	0.5	4.4	11.6	3.2	-1.3	-1.6	3.4	1.3	0.3	-0.0	-2.6
BMI	0.7	3.9	10.3	-2.0	-0.9	-1.0	-2.3	-3.0	-3.2	0.2	-0.6
Height	0.7	14.4	54.6	5.7	1.4	-0.5	7.4	4.2	2.1	-1.7	0.5
Waist Hip Ratio (WHR)	0.2	0.8	1.8	-0.8	-1.1	-1.2	-0.8	0.5	-1.4	0.1	-0.0
Systolic Blood Pressure	0.2	1.2	4.2	0.1	-1.4	-2.0	0.6	0.8	1.0	-0.1	-1.0
Smoking Status	0.4	1.0	3.9	1.1	0.0	0.1	0.9	0.3	-2.0	0.9	1.2
Allergy or Eczema	1.7	4.5	9.6	-2.0	-1.6	-2.6	-3.1	-1.7	-2.8	-0.4	-1.6
Cardiovascular Disease	0.4	1.5	3.8	-0.3	-1.6	-1.7	-0.5	0.6	-1.1	1.9	0.8
Hypothyroidism (self reported)	0.2	0.6	1.4	0.8	-0.0	-0.2	1.0	-0.8	-1.2	0.7	-0.2
Respiratory disease	1.5	3.4	6.6	-1.9	-1.1	-2.5	-2.6	-0.8	-2.2	-1.7	-1.1
Type 2 Diabetes (T2D) (2018)	0.3	0.5	2.2	1.5	0.2	1.2	0.5	0.3	0.4	0.2	0.0
Lung FEV1/FVC ratio	0.5	2.3	6.8	1.6	-0.7	-1.4	2.6	-0.3	1.6	-0.1	-2.0
Lung FVC	0.3	1.4	3.7	1.1	0.3	-0.5	1.3	1.9	1.8	-1.0	0.4
Neuroticism	0.8	1.8	4.7	-0.1	-1.8	-1.5	-0.0	0.7	-0.0	2.0	-2.2
Chronotype (morning person)	0.3	0.7	2.7	-1.3	0.4	0.0	-1.6	-0.4	0.7	-0.4	-0.1
Hair Pigment	0.0	1.3	5.0	0.9	0.8	-0.2	1.2	0.1	-1.5	-2.2	-0.0
Tanning	0.1	1.4	3.8	-1.7	-0.4	0.1	-2.0	-1.7	-1.1	-0.3	-0.3
Hand grip strength (left)	0.7	1.8	3.9	1.6	1.8	-0.7	1.8	-0.2	-0.3	-2.0	0.5
Number of treatments/medications taken	1.4	2.6	7.2	0.2	-2.4	-2.7	-0.4	-0.7	-1.7	1.0	-1.7
Average weekly spirits intake	1.2	1.5	4.1	1.7	-0.6	-1.7	1.4	-2.0	0.3	0.1	-0.0
Sensitivity / hurt feelings	1.6	2.8	5.3	1.7	-1.7	-1.3	1.7	2.3	1.3	1.6	-1.7
Frequency of depressed mood in last 2 weeks	0.7	1.0	5.0	0.5	0.3	-0.0	-0.0	2.2	1.4	0.4	-0.7
Hearing difficulty/problems: Yes	0.2	0.3	0.8	-0.6	-0.5	0.1	-0.4	-0.1	-0.9	0.7	-0.6
Relative age of first facial hair	0.4	0.8	3.7	-0.4	0.4	-0.4	-0.5	-1.2	-1.9	-0.2	-0.2
Other serious medical condition/disability diagnosed by doctor	0.5	0.7	1.5	-0.4	0.5	-1.1	-0.5	-1.1	-0.8	-0.4	-1.2
Ever used hormone-replacement therapy (HRT)	2.8	3.6	11.8	-0.1	-2.6	-3.4	-0.8	-1.3	-2.1	0.4	-1.9
Ever had hysterectomy (womb removed)	0.9	1.0	2.2	0.2	1.2	-1.3	-0.0	-0.4	-1.2	-1.5	1.1
Systolic blood pressure, automated reading	0.3	0.7	3.5	-0.2	-1.1	-1.9	-0.2	0.5	0.1	-0.2	-0.9
Eye problems/disorders: Diabetes related eye disease	1.4	1.5	4.5	-2.1	-0.0	0.3	-2.1	-1.4	-0.4	1.0	-0.2
Angina	2.5	3.3	9.8	2.2	-2.1	0.6	1.7	0.5	0.4	3.1	-1.9
Medication for hormone replacement therapy	0.6	0.7	3.3	0.7	-0.6	-0.3	0.3	0.4	-0.4	0.9	-1.8
Vitamin and mineral supplements	0.2	0.2	0.7	-0.8	0.4	0.3	-0.5	-0.6	-0.5	-0.3	0.2
Supplements: Zinc	0.8	0.9	2.6	1.6	0.6	-0.1	1.4	0.9	0.1	0.6	1.1
Medication: Co-codamol	1.2	1.4	3.0	0.8	-1.5	-1.6	0.8	-0.1	-1.7	1.4	-0.7
Medication: Metformin	0.2	0.2	0.7	0.2	0.3	0.7	-0.3	-0.1	0.8	-0.3	-0.5
Diabetes (father)	0.7	0.9	2.4	-1.0	0.5	0.4	-1.4	-1.5	-0.8	-0.2	0.7
Diabetes (mother)	0.9	1.2	2.9	-0.5	-0.8	-1.4	-0.7	1.6	1.7	0.7	-0.1
Severe depression (siblings)	0.4	0.5	1.5	-0.3	0.9	-0.1	-0.3	-0.7	-1.2	-0.4	-0.7
Pack years adult smoking proportion	1.4	2.1	8.2	2.3	-0.2	-0.6	2.9	1.5	0.2	-0.8	-0.1
Impedance of leg (right)	0.1	0.3	1.1	-0.3	-0.2	0.3	-0.3	0.1	-0.8	0.4	1.1
Leg fat-free mass (left)	0.1	0.8	2.5	0.5	1.5	-0.1	1.0	-0.4	-0.3	-1.6	0.3
Trunk fat percentage	0.2	0.7	1.7	-1.1	-0.9	0.2	-1.3	-1.0	-0.7	0.3	-0.5
Hand grip strength (right)	0.6	1.6	4.0	1.6	1.4	-0.5	1.7	-1.0	-0.3	-2.0	0.4
Townsend deprivation index at recruitment	0.3	0.5	1.6	0.7	0.4	0.7	0.4	1.3	0.9	-0.3	0.5
Current tobacco smoking	0.6	1.0	6.5	0.0	-0.1	-0.5	0.7	-0.6	-2.5	0.4	-0.1
Average weekly fortified wine intake	0.8	1.0	5.5	0.1	-0.9	-0.3	-0.5	-0.9	-0.4	0.4	-2.4
Maternal smoking around birth	0.4	0.6	1.7	1.1	-0.6	0.6	0.8	0.8	-0.0	1.3	-0.1
Fed-up feelings	0.3	0.5	2.1	-1.1	0.2	-0.3	-1.4	0.7	-0.4	0.4	-0.2
Frequency of unenthusiasm / disinterest in last 2 weeks	0.6	0.8	2.1	-0.8	-0.8	-1.4	-0.9	0.1	-0.4	-0.6	-1.2
Relative age voice broke	2.1	3.2	10.2	-3.2	0.9	-0.2	-2.2	-2.5	-1.8	-0.1	0.7
Taking other prescription medications	1.0	1.5	4.5	0.1	-1.4	-2.1	-0.5	-1.0	-1.5	1.0	-0.8
Age when periods started (menarche)	1.3	3.0	8.4	-0.9	-1.9	-1.8	-0.6	-2.1	-2.9	1.8	-0.4
Bilateral oophorectomy (both ovaries removed)	0.6	0.7	3.6	-0.3	-0.8	-1.9	-0.8	0.3	0.2	-0.2	-0.9
Heel bone mineral density (BMD) T-score, automated (left)	0.7	1.7	6.4	1.1	-0.2	-2.0	1.0	0.5	-0.2	-0.5	-2.5
Tinnitus: Yes, but not now, but have in the past	0.4	0.4	1.3	-0.9	0.1	-0.1	-0.2	-1.1	-0.6	-0.5	0.7
Qualifications: CSEs or equivalent	0.7	0.9	3.1	-1.8	-0.6	-0.2	-1.3	-0.6	-0.8	-0.2	0.9
Serious illness, injury or assault to yourself	1.8	2.2	4.5	-1.0	-1.6	-1.6	-1.8	-1.9	-2.1	0.4	-0.3
High blood pressure	0.6	1.6	5.4	0.6	-1.6	-1.4	0.4	1.6	-0.2	2.3	0.3
Hayfever, allergic rhinitis or eczema	2.0	4.4	7.6	-1.6	-1.6	-2.7	-2.6	-2.0	-2.8	-1.0	-1.8
Multivitamins +/- minerals	0.1	0.2	0.4	0.7	-0.1	0.2	0.2	0.6	0.5	0.7	0.0
Stomach or abdominal pain in last month	0.4	0.5	2.0	-0.9	-0.4	-0.1	-1.4	-0.6	0.2	-0.5	0.2
Supplements: Glucosamine	1.3	1.7	5.0	1.3	-1.9	0.1	0.9	0.9	0.3	2.2	-1.4
Diverticular disease/diverticulitis (self-reported)	0.3	0.3	0.7	-0.8	0.5	0.6	-0.9	-0.4	-0.4	0.2	0.6
Medication: Atenolol	0.3	0.4	1.5	0.1	-0.2	-1.2	-0.1	1.1	-0.0	-0.4	0.3
Medication: Levothyroxine sodium	0.5	0.9	2.6	0.2	-1.2	-1.6	0.5	-0.5	-0.5	1.2	-0.7
Sitting height	0.4	2.6	10.8	2.5	0.6	-1.1	3.3	0.4	0.5	-1.4	0.4
Chronic bronchitis/emphysema (father)	0.6	0.7	2.4	0.0	0.2	-1.4	-0.0	1.6	0.8	-0.8	-0.1
High blood pressure (mother)	0.8	1.2	3.1	0.7	-0.6	-0.8	1.0	1.7	0.8	1.8	-0.5
Body mass index (BMI)	0.5	2.0	4.9	-1.8	-0.8	-0.7	-2.2	-1.9	-1.5	0.3	-0.9
Impedance of leg (left)	0.1	0.3	0.7	0.4	-0.6	0.6	0.4	0.3	-0.5	0.8	0.4
Leg predicted mass (left)	0.1	0.8	2.4	0.6	1.3	-0.2	1.1	-0.4	-0.4	-1.6	0.3
Trunk fat mass	0.1	0.3	1.1	-0.5	-0.4	-0.2	-0.5	-0.8	-1.0	-0.2	-0.2
Waist circumference	0.2	0.7	1.9	-0.8	-0.7	-1.1	-1.4	-0.2	-1.1	0.3	-0.6
Number of incorrect matches in round	0.7	1.2	2.0	-0.7	-1.1	-1.4	-1.2	-0.8	-1.3	-0.1	-1.4
Past tobacco smoking	0.3	0.5	2.0	-1.4	0.3	-0.3	-1.1	-0.3	0.2	-0.7	0.1
Alcohol usually taken with meals	0.7	1.2	3.0	0.2	0.5	-1.1	-0.1	-1.7	-1.1	-0.9	-1.7
Nervous feelings	0.4	0.7	1.4	1.2	-0.0	-0.0	1.2	1.2	1.1	0.6	-0.3
Frequency of tenseness / restlessness in last 2 weeks	0.3	0.5	1.8	-0.1	-1.1	-0.6	-0.4	0.1	0.3	0.6	-1.3
Hearing difficulty/problems with background noise	0.1	0.2	0.7	0.2	-0.6	-0.4	0.3	-0.3	-0.8	0.5	-0.2
Hair/balding pattern: Pattern 2	1.2	1.5	4.0	-1.0	1.4	-0.6	-0.9	-1.5	-1.1	-2.0	0.7
Had menopause	0.8	1.0	4.9	0.2	-0.0	-1.0	-0.1	-1.2	-2.2	0.3	0.7
Had other major operations	0.5	0.6	1.9	0.6	-0.7	-0.3	0.6	-0.4	-1.4	0.9	-0.9
Forced vital capacity (FVC)	0.5	1.9	5.5	2.0	0.6	-0.1	2.4	1.7	1.0	-0.8	0.8
Heel bone mineral density (BMD) T-score, automated (right)	0.5	1.2	4.2	0.8	-0.4	-1.7	0.8	1.0	0.3	0.0	-2.0
Ever unenthusiastic/disinterested for a whole week	1.1	1.4	3.1	0.3	1.8	0.8	-0.3	1.7	0.0	-1.3	1.5
Qualifications: None of the above	1.3	2.7	10.4	0.4	-2.1	0.1	0.6	1.9	1.2	3.2	-1.1
Financial difficulties in last 2 years	0.4	0.5	1.4	0.7	1.1	1.2	0.1	-0.1	0.3	-0.8	-0.1
Mouth/teeth dental problems	0.3	0.5	1.5	-1.2	0.8	-0.3	-0.7	-0.3	-0.8	-0.4	0.4
Heart attack	2.3	3.0	8.6	2.9	-0.8	-1.3	2.5	1.8	1.2	0.8	-1.2
Allergy	2.5	5.7	10.8	1.9	1.8	3.3	2.7	1.9	3.2	1.6	2.0
Pain all over the body in last month	0.5	0.5	1.5	-0.8	0.7	0.6	-0.4	1.0	0.2	1.2	-0.3
Diabetes (self-reported)	0.1	0.2	0.5	0.5	0.3	0.4	0.2	0.7	-0.0	-0.1	0.5
Hayfever/allergic rhinitis (self-reported)	2.3	3.1	9.5	-1.1	-1.0	-0.4	-2.1	-3.1	-2.6	-1.1	-0.8
Medication: Ramipril	0.4	0.5	1.9	0.7	-0.5	-0.8	0.3	0.2	0.4	1.4	-0.7
Medication: Simvastatin	0.4	0.7	1.8	-0.1	-1.4	-1.2	-0.4	-0.4	-0.8	0.8	-0.5
Fluid intelligence score	0.5	1.1	2.9	1.6	1.3	-0.1	1.7	0.8	0.7	-0.8	-0.2
Illnesses of siblings	0.5	0.8	3.9	0.4	-0.2	2.0	0.4	-0.7	1.1	0.4	-0.1
Neuroticism score	0.7	1.5	4.3	0.1	-1.4	-1.4	0.0	1.2	0.4	2.1	-1.4
Weight	0.1	0.4	1.2	0.1	0.2	-0.7	0.2	-0.8	-1.1	-0.6	-0.1
Impedance of arm (right)	0.3	1.6	3.4	1.4	0.0	1.9	1.2	1.8	1.4	1.0	-0.0
Arm fat percentage (right)	0.3	1.3	3.0	-1.2	-1.3	0.2	-1.7	-1.1	-1.0	1.0	-1.0
Trunk fat-free mass	0.3	2.0	4.8	1.4	1.3	-1.6	2.2	-0.5	-1.4	-1.7	0.1
Hip circumference	0.1	0.3	0.8	-0.1	0.0	-0.5	-0.9	-0.6	-0.8	-0.4	-0.3
Time employed in main current job	0.6	0.7	1.9	-0.9	0.2	1.0	-1.4	-0.7	0.6	0.3	0.9
Alcohol intake versus 10 years previously	0.5	0.8	2.9	0.6	-1.1	-0.7	0.7	0.5	0.7	0.3	-1.7
Father’s age at death	0.4	0.6	2.1	0.0	0.5	-0.0	1.0	-1.4	-0.2	-1.1	-0.2
Worrier / anxious feelings	0.2	0.4	1.3	-0.5	-0.5	-1.2	-0.7	0.3	0.9	0.1	-0.6
Frequency of tiredness / lethargy in last 2 weeks	1.1	1.8	5.5	-0.2	-2.3	-1.3	-0.7	0.5	1.2	1.8	-1.3
Falls in the last year	1.2	1.6	6.9	-0.4	-1.4	-0.1	-0.2	-1.0	-1.7	2.6	0.3
Hair/balding pattern: Pattern 3	2.0	3.0	6.8	2.0	-1.6	0.0	2.1	2.6	0.3	1.2	-2.2
Number of live births	0.8	1.1	3.0	0.7	-0.5	1.4	0.5	0.3	0.3	1.7	-1.7
Forced expiratory volume in 1-second (FEV1)	0.6	2.1	5.7	2.1	0.2	-0.7	2.4	1.5	1.8	-1.0	-0.1
Pulse rate	0.2	0.4	0.8	0.2	-0.6	0.2	0.9	0.8	0.4	0.9	-0.0
Happiness	1.6	1.9	5.5	0.6	1.6	0.5	0.8	2.3	1.8	-1.7	0.2
Noisy workplace	0.3	0.4	1.2	-0.9	0.4	0.8	-1.1	-0.1	-0.5	-0.1	0.2
Qualifications: A levels/AS levels or equivalent	0.2	0.4	1.7	0.5	-0.3	0.1	-0.0	-0.0	0.8	0.8	-1.3
Serious illness, injury or assault of a close relative in last 2 years	1.2	1.4	4.9	-0.3	-1.9	-2.2	-0.2	-0.7	-0.2	0.8	-1.2
Mouth/teeth dental problems: Dentures	0.4	0.7	1.8	1.2	-0.3	0.6	1.4	1.1	0.7	0.3	0.5
Asthma	1.4	2.8	5.5	-1.4	-1.5	-2.2	-2.3	-0.2	-1.3	-1.0	-2.4
Medication: Ibuprofen (e.g. Nurofen)	0.7	0.9	1.5	-0.8	-0.3	-0.7	-1.2	-1.2	-1.2	-0.9	-0.8
Medication: Cholesterol lowering	0.7	1.1	3.6	-0.0	-1.8	-1.9	0.4	-0.1	-0.9	0.3	-0.9
Depression (self-reported)	0.6	0.7	1.9	0.1	-0.5	-1.0	0.3	0.7	0.0	1.4	-1.3
Medication: Lansoprazole	1.3	1.5	4.8	-0.7	-1.5	-0.2	-0.8	-1.2	0.3	2.2	-1.5
Prospective memory result	1.5	1.8	5.3	-0.1	-2.3	-1.8	-0.2	-1.1	-0.8	0.7	-1.8
Lung cancer (father)	0.8	0.9	3.1	-1.8	-0.6	-0.1	-1.6	-0.6	-0.3	-0.5	-0.6
Illnesses of mother	1.1	1.3	3.4	-1.1	0.6	0.9	-1.2	-1.6	-0.8	-1.8	0.4
Forced expiratory volume in 1-second (FEV1), Best measure	0.6	1.8	4.1	2.0	-0.4	-0.4	2.0	1.4	1.9	-0.1	-0.7
Pulse wave Arterial Stiffness index	1.2	1.4	2.8	-1.4	-1.7	-1.0	-0.8	-1.3	-0.6	1.4	-0.9
Impedance of arm (left)	0.2	0.9	1.9	1.1	-0.4	1.2	1.0	1.1	1.4	0.2	-0.3
Arm fat mass (right)	0.2	1.0	2.0	-1.0	-0.7	-0.6	-1.2	-1.4	-1.3	0.1	-0.7
Trunk predicted mass	0.4	2.0	4.5	1.3	1.3	-1.7	2.1	-0.5	-1.5	-1.8	0.1
Standing height	0.7	6.8	26.8	3.7	1.9	-0.3	5.2	1.7	0.6	-2.1	1.6
Length of working week for main job	0.4	0.5	0.9	-0.9	0.3	0.9	-0.7	-0.8	-0.6	0.7	0.4
Exposure to tobacco smoke at home	0.8	0.9	2.1	-1.5	0.4	0.8	-1.2	-1.4	-0.1	-0.2	0.4
Breastfed as a baby	0.6	0.8	2.3	1.1	-0.3	-0.3	1.1	-0.5	1.5	0.0	-1.0
Tense / ‘highly strung’	0.6	1.1	2.2	0.8	-0.8	-1.5	1.2	1.3	-0.7	0.6	-1.1
Seen doctor (GP) for nerves, anxiety, tension or depression	0.5	0.7	2.6	0.4	-0.3	-1.6	-0.5	0.2	-1.5	-0.4	-0.2
Hair/balding pattern: Pattern 4	0.5	1.3	3.0	-1.6	1.5	1.7	-1.2	-0.6	0.0	-0.3	0.9
Birth weight of first child	0.2	0.4	1.0	-0.5	0.6	1.0	-0.3	-0.1	-0.5	0.4	0.9
Peak expiratory flow (PEF)	0.1	0.3	1.4	0.4	-0.0	-0.5	0.4	0.6	1.2	-0.7	-0.1
Pulse wave reflection index	0.6	0.7	2.0	-0.8	0.4	-0.3	-0.9	-1.4	-1.4	-0.4	0.2
Ever highly irritable/argumentative for 2 days	0.3	0.3	1.3	-0.1	0.5	0.5	-0.1	-0.4	-0.1	-0.7	-1.1
Loud music exposure frequency	0.4	0.5	2.3	0.3	0.6	0.8	0.4	1.5	0.4	-0.0	-0.0
Qualifications: O levels/GCSEs or equivalent	0.2	0.3	1.5	-0.3	-0.1	-0.7	-0.4	0.0	0.3	0.4	-1.2
Mouth/teeth dental problems: Bleeding gums	0.5	0.7	2.2	1.3	-0.3	-0.5	0.6	0.3	0.7	-0.4	-1.5
Blood clot in the leg (DVT)	2.5	3.2	9.5	0.6	1.2	-1.4	1.1	-1.7	-3.1	-2.8	0.4
Medication: Paracetamol	0.7	1.2	4.8	-0.9	-1.2	-0.0	-2.2	-0.9	0.4	0.3	-1.1
Headache pain in last month	2.1	3.5	6.9	-0.9	-2.6	-2.1	-1.9	-1.7	-2.5	0.7	-1.6
Medication for cholesterol, blood pressure or diabetes	1.1	1.9	8.2	-0.4	2.9	1.2	-0.6	-0.1	0.0	-2.1	0.6
Glaucoma (self-reported)	0.3	0.4	1.7	-0.2	0.1	1.3	-0.2	-0.8	-0.3	0.6	-0.4
Gout (self-reported)	1.0	1.3	4.9	-0.8	1.2	1.1	-0.7	1.1	0.4	-0.7	2.2
Hypothyroidism/myxoedema (self-reported)	0.6	1.1	4.2	0.8	-0.7	-2.0	0.9	-0.7	-1.3	0.7	-0.5
Medication: Amlodipine	0.6	0.8	2.6	-0.7	0.3	-1.1	-0.4	-1.6	-0.5	-0.9	0.8
Medication: Ventolin 100micrograms inhaler	0.6	0.8	2.7	-0.7	-1.6	-0.9	-1.1	-0.4	-0.7	0.3	0.7
Birth weight	0.4	0.9	2.6	0.4	0.5	1.4	0.8	1.2	1.6	0.5	0.2
Chronic bronchitis/emphysema (mother)	0.5	0.6	1.8	-0.6	-1.2	-0.4	-0.4	0.4	-0.2	1.3	-0.8
High blood pressure (siblings)	0.4	0.5	3.1	0.3	0.7	-0.4	0.1	1.8	0.5	-0.0	-0.3
Forced vital capacity (FVC), Best measure	0.5	1.9	5.6	2.4	-0.2	0.2	2.3	1.6	1.3	0.4	0.3
Body fat percentage	0.3	1.0	3.1	-1.3	-1.1	-0.2	-1.8	-0.8	-1.1	0.5	-0.5
Leg fat percentage (right)	0.6	2.2	7.3	-2.0	-0.9	-0.6	-2.7	-1.2	-1.7	0.7	-0.3
Arm fat-free mass (right)	0.3	1.5	3.8	0.4	1.4	-1.3	1.2	-0.9	-1.3	-1.9	0.5
Exposure to tobacco smoke outside home	1.1	1.5	7.5	0.8	-1.6	-0.4	0.9	0.6	0.1	2.7	-0.2
Comparative body size at age 10	1.0	2.7	11.8	0.3	3.4	2.6	-0.4	-0.6	0.2	-1.2	1.2
Number of full brothers	1.3	1.6	4.9	-0.0	-0.5	0.1	-0.6	-2.2	-1.7	1.8	-1.2
Worry too long after embarrassment	0.9	1.5	4.0	0.7	-0.6	-0.5	1.5	1.7	2.0	1.1	-0.7
Seen a psychiatrist for nerves, anxiety, tension or depression	1.8	2.3	8.0	2.0	-0.4	-1.9	1.6	0.2	-0.5	0.4	-2.8
Wheeze or whistling in the chest in last year	0.3	0.6	1.4	-0.7	-1.2	-0.9	-0.4	0.2	-1.1	0.4	-0.5
Number of children fathered	1.3	1.4	4.9	-0.1	-1.6	-0.6	0.2	-0.9	-1.0	2.2	-1.3
Reason for reducing amount of alcohol drunk: Health precaution	0.6	0.7	2.4	1.0	1.2	0.6	0.5	0.8	0.3	0.0	1.5
Age at first live birth	0.4	0.8	2.8	-1.7	0.9	0.2	-0.8	-0.3	-0.4	-1.2	-0.1
Pulse wave peak to peak time	1.4	1.6	2.8	1.7	1.7	1.0	1.1	1.5	0.8	-1.3	0.8
Health satisfaction	0.2	0.2	0.6	0.2	-0.3	0.1	0.2	-0.5	0.5	0.8	0.7
Shortness of breath walking on level ground	1.1	1.3	2.9	-1.7	1.0	1.1	-1.1	-0.6	1.0	0.8	1.5
Qualifications: College or University degree	0.5	1.7	5.4	1.2	1.5	0.1	1.4	-1.4	-0.8	-2.3	0.1
Eye problems/disorders: None of the above	1.4	1.6	4.6	1.3	1.2	-0.1	2.1	1.6	0.8	-1.4	0.4
Mouth/teeth dental problems: Loose teeth	1.4	1.6	5.2	0.9	-1.9	0.0	0.7	0.3	1.0	2.3	-1.3
Emphysema/chronic bronchitis	0.7	0.8	3.3	0.1	0.1	-0.4	0.2	1.6	1.8	0.4	-0.3
Medication for pain relief, constipation, heartburn	0.7	1.2	3.8	0.7	1.9	1.4	1.2	0.5	0.8	-1.0	0.5
Neck or shoulder pain in last month	1.3	1.9	3.6	-0.6	-1.5	0.7	-0.8	-1.8	-1.4	1.6	-1.9
Medication: Blood pressure	0.8	1.4	4.4	0.8	-2.1	-0.7	1.2	0.5	0.2	1.9	-0.2
Angina (self-reported)	2.4	3.2	8.2	2.3	-2.0	0.5	1.8	0.5	0.4	2.9	-2.0
Migraine (self-reported)	0.3	0.4	1.6	-0.4	-0.4	0.4	-0.4	-0.3	-1.3	0.8	0.5
Medication: Ibuprofen	0.7	0.8	2.0	-0.4	0.4	-0.8	-1.1	-0.1	-1.4	-1.4	0.2
Medication: Allopurinol	0.2	0.3	0.7	-0.6	0.4	0.1	-0.7	0.7	-0.4	0.2	0.8
Medication: Omeprazole	1.3	1.5	3.6	-1.9	0.4	-1.4	-1.2	-0.2	-1.3	0.5	1.7
Medication: Seretide 50 evohaler	1.2	1.4	6.4	-1.5	0.1	0.1	-2.5	-1.2	-1.0	0.2	0.4
Mean time to correctly identify matches	1.2	2.3	3.7	1.9	-1.6	-1.7	1.6	1.2	0.9	-0.8	-1.9
Heart disease (mother)	0.6	0.8	2.0	0.0	0.9	-0.8	0.8	0.9	0.9	-0.5	1.4
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.5	0.5	1.2	0.6	-1.1	-0.7	0.6	0.4	0.5	-0.7	-1.0
Whole body fat mass	0.2	0.6	1.9	-0.8	-0.6	-0.6	-1.0	-0.9	-1.4	-0.1	-0.2
Leg fat mass (right)	0.3	1.1	2.8	-1.2	-0.5	-0.6	-1.5	-1.3	-1.7	-0.1	-0.2
Arm predicted mass (right)	0.3	1.3	3.1	0.7	1.3	-1.1	1.4	-0.6	-1.2	-1.8	0.5
Pulse rate, automated reading	0.1	0.4	1.2	-1.1	-0.0	0.5	-1.0	0.8	0.1	-0.1	0.3
Alcohol intake frequency.	0.2	0.4	0.7	-0.4	-0.8	-0.5	-0.8	0.3	0.1	0.6	-0.8
Comparative height size at age 10	0.4	2.1	6.9	1.7	1.6	0.0	2.6	0.7	-0.1	-1.3	1.4
Number of full sisters	0.6	0.8	2.1	-0.2	-0.7	-0.3	-0.1	1.4	-0.3	1.2	1.4
Suffer from ‘nerves’	1.4	2.2	6.0	0.9	-1.6	-2.5	1.0	1.0	-0.2	2.1	-1.5
Overall health rating	0.9	2.0	7.8	-0.8	-1.9	-0.4	-0.9	-0.4	-1.0	2.8	-1.2
Chest pain or discomfort	1.6	2.3	9.9	0.8	-1.8	-2.1	-0.4	0.2	0.0	0.6	-3.1
Had major operations	0.7	0.8	3.1	0.3	-0.4	-0.6	0.3	-0.3	-1.8	-0.8	-1.5
Age at last live birth	0.8	1.2	4.3	-1.3	1.4	2.1	-0.6	-0.7	-0.3	-0.4	-0.0
Family relationship satisfaction	0.7	0.9	3.8	0.0	0.0	-1.7	-0.4	-0.7	-0.3	-1.9	-0.3
Leg pain on walking	0.2	0.3	0.7	-0.8	0.7	0.7	-0.6	-0.2	-0.0	0.1	-0.3
Qualifications: NVQ or HND or HNC or equivalent	0.4	0.5	1.7	-0.3	1.3	0.3	-0.7	-0.4	-0.5	-0.1	1.1
Commuting to job workplace: Car/motor vehicle	1.1	1.3	2.9	-1.7	-1.3	-1.3	-1.2	-1.2	-0.9	0.2	-0.7
Illness, injury, bereavement, stress in last 2 years	1.2	1.4	5.1	-0.2	1.7	2.3	0.3	0.7	0.8	-1.1	1.0
Medication: Aspirin	0.8	1.1	3.5	0.4	-1.7	-1.2	0.4	0.5	-0.6	1.9	0.0
Supplements: Vitamin C	0.2	0.2	0.3	-0.4	-0.5	-0.4	-0.5	-0.2	-0.5	0.1	-0.6
Knee pain experienced in last month	0.5	0.7	2.7	0.1	-1.5	0.2	0.0	-0.3	-0.4	1.7	-0.6
Hypertension (Self-reported)	0.6	1.6	4.5	0.1	-1.5	-1.5	-0.3	1.6	-0.5	2.1	0.9
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.8	0.9	2.3	-1.3	-0.1	0.9	-0.3	-0.7	1.3	1.5	0.5
Illnesses of father: Heart disease	1.1	1.5	4.5	-1.9	-0.5	-0.2	-1.5	-0.9	0.4	2.1	0.4
Illnesses of siblings: Diabetes	1.9	2.3	9.7	-0.5	-0.6	-3.1	-0.6	-0.5	-2.4	-1.4	-0.3
Smoking status: Previous	0.5	0.7	2.7	1.6	-0.4	0.6	1.0	0.8	0.4	0.8	-0.1
Forced expiratory volume in 1-second (FEV1), predicted	0.8	1.7	7.0	1.8	0.6	0.3	2.7	1.3	0.5	-1.1	0.0
Whole body fat-free mass	0.2	1.3	2.8	1.0	1.3	-1.0	1.6	-0.5	-1.0	-1.7	0.2
Leg fat-free mass (right)	0.2	1.0	2.6	1.1	1.3	0.1	1.6	0.1	0.1	-1.4	0.1
Arm fat percentage (left)	0.4	1.6	3.5	-1.4	-1.5	-0.4	-1.9	-1.4	-1.1	0.6	-1.2
Average weekly red wine intake	0.9	1.4	3.2	1.4	1.3	0.7	1.4	0.1	1.8	-1.3	-0.2
Handedness (chirality/laterality): Left-handed	0.8	1.0	3.0	0.3	1.0	1.3	-0.1	1.7	0.9	0.3	1.1
Mood swings	1.1	1.9	4.2	-0.1	-2.1	-2.0	-0.6	-0.3	-1.3	1.3	-1.8
Loneliness, isolation	0.6	0.8	3.7	0.2	0.2	-1.3	0.1	1.9	0.8	0.7	-0.2
Long-standing illness, disability or infirmity	1.6	2.5	7.2	-1.9	-0.6	-0.3	-2.7	-1.8	-1.6	1.6	-0.8
Ever had bowel cancer screening	0.3	0.4	1.5	-0.7	0.6	0.4	-1.2	-0.5	-0.2	-0.0	-0.3
Diabetes diagnosed by doctor	0.1	0.1	0.6	0.1	0.3	0.8	-0.4	0.1	0.0	0.2	0.2
Ever had stillbirth, spontaneous miscarriage or termination	1.1	1.2	4.3	1.0	-0.9	-1.3	1.0	0.5	0.1	0.8	-2.1
Friendships satisfaction	0.9	1.1	4.2	1.2	-0.5	0.3	0.8	0.4	1.3	0.7	-2.0
Qualifications: nursing, teaching	0.7	1.0	2.8	-0.1	-0.8	-0.8	-0.4	-1.3	-1.4	0.6	-1.7
Commuting to job workplace: Walk	1.8	2.0	5.8	1.1	1.1	2.4	0.8	-0.8	-0.4	0.9	2.3
Eye problems/disorders: Cataract	1.1	1.3	4.0	-1.9	-0.1	0.1	-2.0	-1.2	-0.8	0.4	-0.4
Mouth/teeth dental problems: Mouth ulcers	0.4	0.6	1.7	-0.6	-1.1	-0.2	-0.4	-1.3	-0.0	1.3	-0.1
Medication for cholesterol	0.9	1.4	5.9	-0.9	0.9	1.1	0.1	-1.6	0.5	-2.4	0.5
Medication: Laxatives (e.g. Dulcolax, Senokot)	2.2	2.6	8.4	-1.5	2.0	2.9	-1.5	-1.1	1.3	-0.8	0.6
Back pain experienced in last month	0.4	0.6	1.5	-0.2	-0.5	-0.6	-0.1	-1.0	-1.2	0.8	-0.9
Mineral and other dietary supplements	1.4	1.8	6.4	-0.6	1.9	0.5	0.2	-0.3	-1.1	-2.5	1.7
Breast cancer (self-reported)	2.7	3.2	7.3	2.6	0.4	0.2	2.7	2.4	1.8	1.1	1.1
Asthma (self-reported)	1.3	2.5	6.0	-1.6	-1.4	-1.8	-2.4	-0.3	-1.3	-0.7	-2.1
Osteoporosis (self-reported)	0.3	0.3	1.1	-0.2	-0.6	-1.0	-0.2	-0.1	-1.0	0.3	-0.1
Osteoarthritis (self-reported)	0.2	0.3	0.9	-0.2	-0.4	-0.0	-0.2	-0.1	-0.9	0.6	0.9
Medication: Aspirin	0.8	1.0	3.6	0.6	-1.3	-1.0	0.7	0.7	-0.4	1.9	0.1
Medication: Gliclazide	0.7	0.8	2.5	0.7	-0.2	0.0	0.9	1.6	1.3	0.2	-1.0
Illnesses of father: None of the above (group 1)	0.4	0.5	2.4	0.9	-0.7	0.3	0.2	-0.7	-1.5	0.3	-0.1
Smoking status: Current	0.7	1.0	6.8	0.1	0.2	-0.6	0.6	-0.8	-2.6	0.1	-0.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.6	1.2	4.3	1.2	0.4	-0.1	1.2	1.1	2.1	0.5	-0.7
Whole body water mass	0.2	1.3	3.0	1.0	1.4	-0.8	1.7	-0.4	-0.9	-1.6	0.3
Leg predicted mass (right)	0.2	1.0	2.6	1.1	1.4	0.1	1.6	0.1	0.2	-1.5	0.1
Arm fat mass (left)	0.2	0.9	1.8	-0.7	-0.8	-0.8	-0.9	-1.4	-1.3	-0.2	-0.9
Number of self-reported non-cancer illnesses	0.7	1.3	2.8	0.5	-1.5	-1.6	-0.2	-0.6	-1.7	1.1	-0.8
Average weekly champagne plus white wine intake	0.1	0.2	0.5	-0.4	0.1	-0.6	-0.2	0.0	-0.7	-0.6	0.3
Miserableness	1.1	1.8	5.4	-0.7	-1.8	-1.6	-0.5	-0.4	-0.8	2.3	-1.5
Guilty feelings	0.8	1.2	3.5	-1.2	-0.7	0.1	-1.6	0.6	1.2	1.9	-0.4
Wears glasses or contact lenses	0.5	0.6	1.4	0.2	0.4	-1.0	1.1	-0.9	-0.3	-1.2	-0.1
Ever taken oral contraceptive pill	1.4	1.5	4.8	0.9	-1.4	-0.9	1.4	1.2	0.4	0.5	-2.2
Hearing aid user	0.7	0.7	1.8	-0.7	0.1	1.1	-0.7	-1.1	-0.7	1.3	-0.4
Mother’s age at death	0.4	0.4	1.3	1.1	-0.2	0.2	1.0	-0.6	0.3	-0.6	-0.5
Financial situation satisfaction	0.5	0.6	2.5	-0.2	1.1	-0.2	-0.4	0.1	-0.7	-1.6	-0.5
Tinnitus: Yes, now most or all of the time	0.7	0.8	2.1	-1.1	-0.2	-0.2	-0.4	-1.4	-1.5	0.7	0.6
Commuting to job workplace: Public transport	1.1	1.4	3.6	-0.3	1.4	1.6	-0.7	-0.2	1.2	-0.7	1.9
Eye problems/disorders: Glaucoma	1.0	1.1	4.2	-0.8	-0.0	0.7	-1.0	-2.0	-1.6	0.0	0.5
Medication: Blood pressure	0.7	1.4	3.6	0.6	-1.1	-1.9	-0.2	1.5	-0.5	1.9	0.2
Pain type(s) experienced in last month: Hip pain	0.4	0.5	2.3	-0.0	-0.2	0.9	-0.3	-0.4	-0.8	1.5	-0.5
Supplements: Fish oil (including cod liver oil)	2.0	2.6	6.7	1.0	-2.0	-0.2	-0.4	0.0	1.9	2.3	-2.6
High cholesterol (Self-reported)	0.5	0.9	4.7	-0.4	-1.1	-2.2	-0.0	0.2	-0.9	-0.2	-0.4
Medication: Bendroflumethiazide	0.6	0.9	1.7	-0.5	-0.4	-1.3	-1.1	0.8	-1.1	1.3	0.9
Medication: Paracetamol	0.4	0.7	2.5	-0.4	-0.9	-0.4	-1.6	0.1	0.9	0.1	-0.9
Medication: Lisinopril	0.6	0.8	2.2	-0.2	0.3	-0.8	-1.0	1.5	-1.0	-0.9	0.8
Medication: Atorvastatin	0.9	1.1	3.9	1.5	-0.3	-0.7	2.0	-0.0	-0.5	-0.4	-1.2
Illnesses of father: High blood pressure	2.7	3.4	11.6	0.3	1.7	2.4	0.8	1.8	3.4	-0.4	1.5
Alcohol drinker status: Never	1.0	1.2	4.2	-1.7	-0.8	1.0	-2.0	0.0	0.8	0.8	0.2
Ever smoked	0.1	0.3	0.8	0.6	0.3	-0.2	0.7	0.3	-0.9	0.2	0.5
Basal metabolic rate	0.2	1.0	2.2	0.7	1.1	-0.8	1.4	-0.6	-1.0	-1.5	0.2
Leg fat percentage (left)	0.5	1.7	5.2	-1.6	-1.0	-0.2	-2.3	-1.1	-1.4	0.9	-0.7
Arm fat-free mass (left)	0.2	1.1	2.7	0.4	1.2	-0.7	1.1	-1.0	-1.6	-1.2	0.5
Number of operations (self-reported)	0.7	1.0	4.7	1.1	-0.6	-1.1	0.5	0.6	-2.2	0.1	-0.5
Average weekly beer plus cider intake	1.0	1.4	2.7	1.0	-0.4	0.8	0.9	1.5	1.6	1.1	-1.6
Irritability	1.1	1.9	5.2	-1.2	-2.3	-1.1	-1.4	-0.7	-0.8	2.0	-0.9
Risk taking	2.5	3.7	13.4	-1.8	0.2	-1.7	-1.5	-2.3	-3.7	-0.9	-1.2
Ever had prostate specific antigen (PSA) test	1.4	1.6	4.2	1.3	0.1	1.7	1.1	1.4	2.1	0.3	-0.9
Fractured/broken bones in last 5 years	1.2	1.6	4.7	-2.2	-0.2	-0.0	-2.1	-0.9	-1.1	-0.3	-1.3
Age started oral contraceptive pill	1.0	1.2	3.2	-0.2	-1.3	-1.6	-0.8	-0.3	0.2	1.3	-1.8
Diastolic blood pressure, automated reading	0.6	1.7	5.5	-2.3	-0.6	-1.2	-2.3	-0.4	-0.8	-0.6	-0.2
Ever depressed for a whole week	0.7	0.9	2.6	-0.5	1.1	0.7	-1.0	-0.3	-0.7	-1.6	1.1
Unable to work because of sickness or disability	0.5	0.6	1.7	-0.9	0.0	0.6	-1.2	-0.0	0.3	0.8	-1.3
Commuting to job workplace: Cycle	0.7	0.9	3.7	0.9	-0.7	-0.8	0.7	0.0	0.2	-0.8	-1.9
Myopia	0.4	0.5	2.4	-0.3	1.6	1.1	-0.3	0.1	0.5	0.3	0.3
Vascular/heart problems diagnosed by doctor	0.9	2.4	8.4	-1.3	1.9	1.3	-0.8	-1.7	0.4	-2.9	-0.1
Cholesterol lowering medication	0.7	1.0	4.9	0.7	-1.2	-0.6	0.4	0.4	-0.3	2.2	-0.8
Medication: Omeprazole (e.g. Zanprol)	1.4	1.7	3.8	-2.0	-0.3	-1.8	-1.3	-0.4	-1.7	0.7	1.3
Pain experienced in last month	0.5	0.8	3.1	-0.3	0.5	0.1	0.2	0.5	1.8	-0.8	1.3
Supplements: Calcium	0.5	0.5	1.5	0.6	0.7	-0.2	0.8	1.2	0.2	0.8	0.6
Basal cell carcinoma (self-reported)	0.6	0.7	3.5	0.4	-0.0	-1.9	0.0	-0.2	-0.9	-0.8	-0.0
Heart attack/myocardial infarction (self-reported)	2.8	3.6	12.0	3.5	-0.6	-1.2	2.8	1.8	1.2	0.7	-1.2
Deep venous thrombosis (DVT) (self-reported)	1.9	2.4	7.3	0.6	1.2	-1.2	0.8	-1.4	-2.7	-2.5	0.4
Heart disease (siblings)	0.5	0.6	1.7	-0.5	1.2	-0.5	-0.8	-0.4	-1.3	-0.1	0.2
Alcohol drinker status: Previous	0.5	0.5	2.1	1.4	0.7	0.3	1.0	0.4	-0.5	-0.3	0.1
Pack years of smoking	1.5	2.2	7.4	2.3	-0.7	-1.3	2.7	1.4	0.1	-0.6	-0.2
Impedance of whole body	0.1	0.6	1.8	0.6	-0.2	1.3	0.8	1.0	0.7	0.4	0.3
Leg fat mass (left)	0.2	0.8	2.2	-1.0	-0.4	-0.3	-1.2	-1.3	-1.5	-0.0	-0.3
Arm predicted mass (left)	0.2	1.1	2.5	0.8	1.3	-0.9	1.6	-0.6	-1.4	-1.2	0.4