TWAS hub - PANX1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1490	0.0400	4.9e-11	0.134	0.114	0.179	0.162	0.185	5.8e-16	1.1e-13	2.6e-21	3.2e-19	4.9e-22
2	GTEx	Adipose Subcutaneous	0.0840	0.0330	1.8e-03	0.056	NA	0.015	NA	0.028	2.2e-05	NA	2.0e-02	NA	2.2e-03
3	GTEx	Artery Tibial	0.0884	0.0306	5.9e-04	0.050	NA	0.058	NA	0.059	8.3e-05	NA	2.5e-05	NA	2.0e-05
4	GTEx	Brain Cerebellar Hemisphere	0.2500	0.0970	6.3e-03	0.041	NA	0.020	NA	0.032	3.3e-02	NA	1.0e-01	NA	5.3e-02
5	GTEx	Cells Transformed fibroblasts	0.1430	0.0450	2.2e-05	0.004	NA	0.035	NA	0.031	1.5e-01	NA	1.2e-03	NA	2.1e-03
6	GTEx	Esophagus Muscularis	0.1480	0.0510	1.7e-04	0.127	NA	0.071	NA	0.125	4.1e-08	NA	3.9e-05	NA	5.4e-08
7	GTEx	Heart Left Ventricle	0.1206	0.0530	7.8e-03	0.011	NA	0.044	NA	0.008	8.4e-02	NA	2.2e-03	NA	1.2e-01
8	GTEx	Nerve Tibial	0.1095	0.0483	4.5e-03	0.092	NA	0.076	NA	0.073	4.5e-07	NA	4.9e-06	NA	7.2e-06
9	GTEx	Testis	0.2310	0.0960	8.8e-03	0.083	NA	0.037	NA	0.085	1.6e-04	NA	9.3e-03	NA	1.3e-04
10	GTEx	Uterus	0.3210	0.1220	7.5e-03	-0.007	NA	0.062	NA	0.050	4.7e-01	NA	2.2e-02	NA	3.5e-02
11	GTEx	Whole Blood	0.0720	0.0300	2.6e-03	0.062	NA	0.045	NA	0.046	2.3e-06	NA	4.9e-05	NA	4.1e-05
12	METSIM	Adipose	0.0484	0.0214	8.4e-04	0.022	0.021	0.029	0.028	0.022	2.7e-04	3.1e-04	2.7e-05	4.2e-05	2.1e-04
13	NTR	Blood	0.0325	0.0115	8.5e-06	0.022	0.013	0.018	0.017	0.023	7.3e-08	2.6e-05	1.5e-06	2.4e-06	5.1e-08
14	ROSMAP	Brain Pre-frontal Cortex	0.0935	0.0346	3.0e-05	0.026	0.048	0.056	0.047	0.054	2.5e-04	8.5e-07	8.7e-08	9.8e-07	1.8e-07
15	YFS	Blood	0.0279	0.0112	8.4e-05	0.028	0.015	0.027	0.033	0.025	1.2e-09	8.0e-06	2.7e-09	5.7e-11	1.2e-08
16	TCGA	Breast Invasive Carcinoma	0.0617	0.0337	8.4e-03	0.002	0.003	0.008	NA	0.003	9.3e-02	6.5e-02	6.0e-03	NA	7.0e-02
17	TCGA	Lung Adenocarcinoma	0.0270	0.0172	7.2e-03	0.012	0.016	0.008	NA	0.014	1.2e-02	5.0e-03	3.6e-02	NA	8.8e-03
18	TCGA	Lung Squamous Cell Carcinoma	0.0367	0.0212	9.3e-03	-0.002	0.016	0.007	NA	-0.002	9.8e-01	4.9e-03	4.8e-02	NA	7.3e-01
19	TCGA	Prostate Adenocarcinoma	0.2613	0.0809	1.7e-05	0.049	0.041	0.068	NA	-0.002	7.0e-06	3.7e-05	1.1e-07	NA	5.3e-01
20	TCGA	Thyroid Carcinoma	0.4340	0.0940	3.8e-10	0.042	0.116	0.116	NA	0.077	5.3e-05	2.1e-11	2.4e-11	NA	6.2e-08

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	17	18	19	20
Hypothyroidism (self reported)	3.9	9.1	26.8	-4.2	-3.0	-4.3	-3.6	-1.1	-4.6	0.6	-0.8	-0.8	-2.2	3.4	-1.4	3.7	-5.2	3.1	4.2	2.4	0.8	-2.3
Diverticular disease/diverticulitis (self-reported)	3.1	3.7	12.4	-1.9	-3.4	-3.5	-2.4	-0.9	-3.0	1.1	-1.2	1.0	-0.4	2.7	0.2	2.9	-1.6	0.8	2.4	-0.2	1.2	0.3
Tinnitus: Yes, but not now, but have in the past	2.8	3.0	10.2	2.3	2.0	2.1	1.4	0.2	2.2	1.1	1.8	2.3	1.3	-1.0	1.9	-0.8	3.2	-0.5	-2.3	-2.2	0.3	1.3
Average weekly beer plus cider intake	2.7	3.9	9.7	2.1	1.8	2.8	2.9	0.6	3.1	-2.2	0.4	-0.3	-0.3	-2.5	0.9	-2.5	2.9	-1.7	-3.0	-1.5	-1.2	0.8
Father’s age at death	2.6	3.5	9.8	-0.8	-1.9	-2.4	-2.4	-0.4	-2.3	2.4	1.4	2.1	1.4	3.0	0.4	3.1	-1.4	2.2	2.5	0.1	1.4	0.8
Exposure to tobacco smoke at home	2.6	2.9	6.5	-0.2	-2.0	-1.9	-1.2	0.5	-1.6	2.5	1.5	1.2	1.3	2.0	1.7	2.5	1.2	2.3	1.3	-0.5	2.5	2.5
Chest pain or discomfort	2.4	3.4	8.2	1.8	2.9	2.9	2.7	1.6	2.8	-1.9	0.3	0.3	0.4	-2.0	1.5	-2.2	2.4	-0.8	-2.5	-0.1	-1.0	1.4
Average weekly spirits intake	2.3	2.8	8.4	2.9	1.7	1.2	0.2	-0.9	1.6	1.6	1.6	2.9	2.4	-0.1	1.1	0.0	2.4	-0.5	-1.7	-2.6	1.3	1.7
Hearing difficulty/problems with background noise	2.0	3.2	9.4	2.4	2.6	2.4	1.3	-0.1	2.6	-0.4	2.0	1.6	3.1	-1.0	1.8	-1.2	2.8	-0.8	-1.8	-1.1	-0.5	1.4
Primary Biliary Cirrhosis	1.9	2.6	6.8	-1.5	-1.3	-1.7	-2.0	0.5	-2.2	1.4	0.4	1.2	1.7	2.1	1.3	2.5	-1.0	2.6	2.3	1.1	0.9	1.8
Respiratory disease	1.8	4.1	10.7	1.8	2.5	2.7	3.2	2.2	2.5	-1.8	-0.4	-1.5	0.5	-2.9	0.3	-3.3	1.7	-2.1	-2.4	0.2	-2.0	-1.1
Qualifications: CSEs or equivalent	1.8	2.4	7.1	2.7	2.5	2.2	1.1	-0.9	2.2	-0.8	2.6	1.4	0.9	-1.0	0.5	-1.0	1.9	-0.6	-2.1	-1.0	-0.0	0.7
Hypothyroidism/myxoedema (self-reported)	1.8	3.5	11.2	-2.8	-1.7	-2.7	-2.5	-0.8	-2.9	0.5	-0.3	-0.5	-1.7	2.1	-0.9	2.5	-3.3	1.7	2.4	0.6	0.4	-1.5
Number of full sisters	1.8	2.2	7.1	0.5	0.9	1.6	2.7	0.1	1.1	-2.1	-1.0	-1.7	0.4	-2.1	-1.8	-2.3	0.5	-0.8	-0.9	1.5	-1.5	-1.8
Illnesses of siblings: Diabetes	1.8	2.2	6.2	1.3	1.6	1.9	2.1	-1.1	1.7	-0.8	0.2	-0.6	-0.2	-2.2	-0.8	-2.2	1.6	-1.9	-2.5	-1.3	-0.7	-1.3
Average weekly champagne plus white wine intake	1.8	2.5	7.0	-0.9	-2.1	-2.0	-2.6	0.3	-1.9	1.0	1.1	1.3	-0.4	2.5	0.9	2.5	-0.3	1.8	2.1	0.8	1.9	-0.1
Eye problems/disorders: Diabetes related eye disease	1.7	1.9	6.0	1.9	1.6	1.6	0.5	0.3	1.9	-1.4	0.7	1.7	0.5	-1.0	1.6	-1.0	2.5	-1.0	-1.8	-1.7	0.0	1.1
Prostate Cancer	1.6	2.2	6.2	1.2	1.6	2.2	2.3	0.7	1.9	-0.5	-0.8	-0.7	-0.2	-2.4	-0.7	-2.3	0.9	-1.7	-2.5	-1.3	-0.7	-0.5
Severe depression (siblings)	1.6	1.8	8.5	1.5	1.7	1.4	1.7	2.9	1.9	-1.5	1.1	0.1	-0.8	-0.8	0.7	-1.5	1.4	-1.4	-0.9	-0.3	-1.6	-0.5
Noisy workplace	1.6	2.0	10.5	1.8	1.1	1.0	1.4	0.2	1.3	0.6	3.2	1.7	0.7	-0.2	1.6	-0.1	2.3	-0.4	-1.4	-2.5	0.8	0.4
Mouth/teeth dental problems: Loose teeth	1.6	1.9	6.2	0.6	0.9	1.1	1.8	-0.6	1.3	-0.9	-2.0	-1.4	0.4	-1.7	-1.5	-2.1	0.1	-2.5	-1.4	-1.0	-2.2	-0.7
Myopia	1.6	2.3	6.6	-1.0	-1.3	-1.8	-1.7	0.6	-1.9	-0.3	1.0	0.8	0.8	2.6	1.0	2.3	-1.4	1.7	2.3	2.0	1.9	-0.7
Allergy or Eczema	1.5	4.0	10.8	2.1	2.2	2.8	2.3	1.5	3.3	-1.1	-0.4	-0.5	1.5	-2.2	0.5	-2.8	2.6	-2.8	-2.5	-1.0	-2.4	0.2
Hair/balding pattern: Pattern 2	1.5	1.9	7.6	0.3	-1.3	-1.1	-1.0	-0.2	-0.1	2.5	1.1	2.1	1.0	1.8	1.1	1.8	0.7	-0.3	-0.0	-2.8	1.9	1.1
Hair/balding pattern: Pattern 3	1.5	2.2	5.4	1.9	2.0	2.2	2.3	1.9	2.1	-1.5	0.0	-0.1	0.1	-1.6	0.1	-2.0	1.3	-0.9	-1.6	0.5	-1.7	0.2
Medication for cholesterol, blood pressure or diabetes	1.5	2.5	10.4	0.3	-0.9	-0.9	-1.9	-1.2	-0.4	1.6	0.9	2.2	1.3	2.1	1.7	2.2	1.3	1.5	0.8	-0.9	2.2	3.2
Reason for reducing amount of alcohol drunk: Health precaution	1.5	1.7	9.3	-1.2	-0.8	-0.3	0.7	-0.6	-0.9	-0.2	-1.1	-2.1	-0.5	-1.2	-3.0	-0.9	-2.0	-0.3	0.1	0.4	-0.3	-2.8
Relative age voice broke	1.4	2.1	6.9	1.8	1.9	1.6	0.6	0.3	1.8	0.2	1.9	2.6	1.1	-0.2	2.2	-0.1	2.0	-0.4	-1.3	-2.2	0.7	0.9
Hayfever, allergic rhinitis or eczema	1.4	3.1	7.3	1.4	2.0	2.6	2.3	1.0	2.7	-1.1	0.1	-0.6	1.4	-2.4	0.4	-2.7	2.1	-2.1	-2.3	-0.9	-2.0	0.2
Medication: Levothyroxine sodium	1.4	2.3	7.0	-2.3	-1.0	-2.3	-2.6	-0.3	-2.1	1.1	-0.1	-0.4	-1.3	1.7	-0.3	1.9	-2.6	1.3	1.8	0.5	0.3	-1.0
Chronic bronchitis/emphysema (father)	1.4	1.6	5.0	2.2	1.4	1.7	1.0	0.3	2.0	-0.6	1.6	1.3	1.2	0.1	1.7	-0.5	1.6	-1.2	-1.5	-1.3	-0.4	0.7
Frequency of tenseness / restlessness in last 2 weeks	1.4	2.2	6.4	-2.4	-2.3	-2.5	-1.8	-1.2	-2.1	-0.0	-1.2	-0.6	-2.0	1.1	-0.5	1.2	-1.7	0.5	1.9	0.7	-1.0	-0.7
Loud music exposure frequency	1.4	1.5	5.2	0.7	1.6	1.6	2.3	0.6	1.4	-0.4	-0.1	-0.5	0.2	-2.0	-0.8	-2.0	0.7	-1.1	-1.9	-0.1	-0.8	-1.4
Asthma (self-reported)	1.4	2.8	6.7	0.9	2.2	2.4	2.4	1.0	2.1	-2.4	-0.6	-1.6	0.3	-2.5	0.0	-2.6	1.4	-1.3	-2.1	0.1	-1.8	-0.3
Wears glasses or contact lenses	1.4	1.6	5.6	-1.6	-0.7	-0.3	0.3	1.0	-0.7	-1.9	-1.7	-2.0	-1.8	-0.2	-1.3	-0.3	-2.4	-0.2	0.7	1.2	-0.7	-1.8
Unable to work because of sickness or disability	1.4	1.9	5.2	0.1	0.7	1.4	1.5	-2.3	1.2	0.3	-1.5	-1.9	-0.5	-2.1	-1.7	-2.1	0.3	-1.6	-1.9	-0.6	-0.8	-0.6
Allergy	1.3	2.9	7.4	-0.9	-1.8	-2.3	-2.2	-0.8	-2.2	0.9	1.0	1.1	-1.1	2.7	-0.0	2.7	-1.8	2.2	2.5	1.3	1.9	-0.0
Friendships satisfaction	1.3	1.6	4.2	-0.6	-1.7	-1.3	-1.6	0.3	-1.5	-0.6	0.9	0.4	-1.6	1.8	0.8	1.6	-0.8	1.6	2.0	1.6	1.1	-0.6
Medication: Blood pressure	1.3	2.6	9.8	-2.5	-1.2	-0.6	0.8	0.3	-1.1	-2.7	-1.9	-3.1	-1.4	-0.9	-1.1	-0.7	-1.8	0.8	1.1	2.7	-1.5	-1.2
Medication: Atorvastatin	1.3	1.7	5.0	-1.5	-2.2	-2.0	-1.0	1.0	-2.0	0.3	-0.6	-0.7	-1.7	1.1	-0.1	0.9	-1.8	-0.0	1.6	0.7	-0.0	-2.0
Ever had prostate specific antigen (PSA) test	1.3	1.5	5.3	-1.5	-0.2	-0.1	0.3	-0.1	-0.5	-0.5	-2.1	-2.3	-0.2	-1.2	-2.1	-1.1	-1.6	-0.3	0.3	1.1	-1.8	-1.6
Ulcerative Colitis	1.2	1.7	4.6	-0.2	1.1	1.7	1.7	0.3	1.1	-1.3	-1.8	-2.0	-0.7	-2.1	-1.1	-2.0	0.2	-0.9	-1.3	0.4	-1.5	-1.1
Townsend deprivation index at recruitment	1.2	1.6	4.8	0.6	1.0	1.6	2.2	1.2	1.3	-1.6	0.4	-0.8	-0.9	-1.9	0.3	-1.9	0.8	-1.3	-1.9	-0.8	-1.5	-1.0
Medication: Atenolol	1.2	1.5	5.4	1.4	1.6	1.7	2.3	1.1	1.8	-0.6	0.2	-0.3	0.4	-1.6	0.1	-2.0	1.0	-1.1	-1.2	0.2	-1.2	-0.5
Weight	1.2	6.0	20.6	-4.5	-3.5	-3.1	-1.6	-0.4	-3.4	-1.6	-2.9	-2.8	-3.5	0.6	-1.7	1.1	-3.8	0.8	2.2	1.9	-0.6	-1.3
Hip circumference	1.2	5.1	19.0	-4.4	-3.1	-2.8	-1.9	-0.2	-3.3	-1.1	-2.4	-2.4	-3.0	1.1	-1.2	1.6	-3.6	1.4	2.4	1.9	-0.3	-0.7
Length of working week for main job	1.2	1.3	3.6	1.1	0.4	1.4	1.9	0.3	1.2	-0.6	-1.8	-0.5	-0.8	-1.6	-1.0	-1.7	1.3	-1.4	-1.9	-0.3	-0.5	0.1
Comparative body size at age 10	1.2	3.3	11.7	-2.8	-1.9	-2.4	-0.7	0.5	-2.8	-1.8	-2.4	-1.4	-0.9	0.7	-1.5	1.1	-3.4	1.0	2.5	1.7	-1.1	-1.2
Ever had stillbirth, spontaneous miscarriage or termination	1.2	1.3	3.3	-0.3	-0.6	-1.1	-0.7	1.0	-1.1	0.9	1.5	0.9	1.4	1.7	1.3	1.8	-0.3	1.8	1.6	0.8	1.0	0.8
Qualifications: nursing, teaching	1.2	1.8	5.8	-2.0	-1.1	-2.1	-2.4	-0.6	-2.2	0.5	0.0	0.3	-0.5	1.0	-0.0	1.6	-2.2	1.3	1.9	0.4	0.9	0.3
Commuting to job workplace: Walk	1.2	1.3	4.5	-0.6	-0.4	0.4	1.1	2.0	-0.3	-1.0	-1.1	-2.0	-1.4	-1.4	-0.8	-1.4	-0.5	-0.7	-0.3	1.2	-0.4	-2.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.2	1.4	7.4	-1.2	-0.7	0.1	-0.3	-2.7	-0.1	0.0	-2.1	-1.4	-1.9	-1.1	-2.0	-0.5	-0.4	-0.5	-1.0	-1.3	-0.8	-0.5
Alzheimer’s Disease (in mother)	1.1	1.3	5.4	-1.0	-0.5	0.7	1.9	1.0	-0.2	-2.3	-1.6	-1.6	0.3	-1.3	-1.0	-1.1	-0.4	0.6	-0.1	2.0	-0.6	-1.0
Fasting Glucose	1.1	1.3	4.7	1.5	2.0	1.0	0.9	-1.1	1.2	-0.3	0.8	0.8	1.3	-0.6	0.0	-0.7	1.8	-0.7	-2.2	-0.9	0.0	1.6
Number of treatments/medications taken	1.1	2.0	4.7	0.4	1.1	1.6	2.2	2.0	1.4	-1.5	-1.0	-2.1	0.1	-1.9	-0.3	-2.2	0.3	-1.1	-1.0	1.0	-1.9	-1.0
Leg fat-free mass (left)	1.1	5.7	19.3	-4.4	-3.4	-2.7	-1.1	-0.2	-3.1	-1.5	-3.1	-3.0	-4.0	-0.1	-2.2	0.4	-3.6	0.4	1.8	1.8	-1.3	-1.6
Leg predicted mass (left)	1.1	5.7	19.1	-4.4	-3.4	-2.7	-1.1	-0.2	-3.1	-1.5	-3.2	-3.0	-4.0	-0.2	-2.1	0.3	-3.5	0.4	1.8	1.9	-1.3	-1.6
Diabetes (self-reported)	1.1	1.7	5.4	0.6	1.2	1.1	1.4	0.2	1.4	-1.7	-1.3	-1.2	-1.1	-1.6	-0.6	-2.2	0.5	-2.3	-1.5	0.1	-1.7	-1.3
Asthma	1.1	2.1	5.4	0.3	1.7	1.9	2.1	1.0	1.5	-2.3	-1.0	-1.8	0.1	-2.3	-0.2	-2.2	0.9	-1.1	-1.7	0.2	-1.5	-0.5
Arm fat mass (right)	1.1	4.6	16.8	-4.1	-2.8	-2.6	-1.3	0.1	-3.0	-2.3	-2.3	-2.6	-2.9	0.3	-1.1	0.8	-3.5	1.0	1.9	1.9	-0.6	-1.2
Breastfed as a baby	1.1	1.3	4.9	-0.6	-1.0	-1.4	-1.5	0.1	-1.1	1.1	-0.3	0.6	0.8	2.2	-0.0	1.9	-0.8	1.5	1.8	1.2	0.9	1.1
Birth weight of first child	1.1	2.0	4.9	1.1	1.5	2.1	2.0	-1.2	1.7	-1.4	-0.2	-0.4	1.3	-2.1	-0.8	-2.2	1.1	-1.5	-2.1	-0.7	-0.9	-0.6
Exposure to tobacco smoke outside home	1.1	1.4	5.4	1.3	1.1	1.0	1.0	1.2	1.0	0.6	1.6	1.3	1.4	-0.7	1.5	-0.3	2.3	0.4	-1.2	-1.1	0.6	1.8
Breast cancer (self-reported)	1.1	1.3	7.5	-0.0	1.3	1.2	1.6	0.8	0.5	-0.5	-0.2	-1.0	2.7	-1.5	-1.4	-1.2	-0.4	-1.0	-1.2	-0.7	-0.6	-0.9
Arm fat mass (left)	1.1	4.4	15.6	-4.0	-2.6	-2.3	-1.1	0.1	-2.8	-2.4	-2.5	-2.7	-3.0	0.1	-1.2	0.6	-3.3	0.7	1.7	1.8	-0.7	-1.2
Medication: Omeprazole (e.g. Zanprol)	1.1	1.3	3.5	0.4	1.4	1.7	1.3	-0.3	1.6	0.2	-0.5	-1.2	0.5	-1.8	-1.2	-1.9	0.9	-1.3	-1.5	-0.6	-1.2	-0.8
Relative age of first facial hair	1.0	2.1	5.0	-1.0	-1.1	-1.4	-1.7	0.7	-1.4	1.5	1.2	1.9	0.2	1.6	2.0	2.2	0.3	2.2	1.3	-0.8	1.9	1.5
Diabetes (mother)	1.0	1.3	5.9	-1.2	-1.4	-1.3	0.1	0.8	-1.1	-1.6	-1.1	-1.1	-0.5	0.3	-1.1	0.1	-1.6	-1.1	1.0	-0.1	-1.5	-2.4
Trunk fat mass	1.0	4.5	14.4	-3.8	-2.9	-2.8	-1.5	-0.2	-3.0	-2.2	-1.9	-2.2	-3.2	0.7	-0.9	1.0	-3.5	0.5	2.0	1.4	-0.3	-1.5
Alcohol usually taken with meals	1.0	1.5	6.4	-1.6	-1.2	-1.6	-1.6	0.8	-1.3	0.4	-1.3	-0.4	-0.2	1.6	-0.7	1.3	-2.5	0.3	2.2	0.9	-0.6	0.0
Hayfever/allergic rhinitis (self-reported)	1.0	1.3	3.5	0.6	1.2	1.8	1.8	1.2	1.9	-0.9	0.6	-0.3	0.4	-1.2	1.3	-1.3	1.7	-0.8	-1.4	-0.4	-0.8	0.9
Time employed in main current job	1.0	1.2	7.5	-0.6	-0.3	-0.3	0.1	-1.6	-0.5	0.3	-1.3	-1.3	0.8	-0.2	-2.7	-0.3	-1.8	-0.6	-0.1	0.4	-1.0	-1.8
Illnesses of mother	1.0	1.2	6.4	1.2	0.5	0.6	-1.0	-2.5	0.8	0.8	1.1	1.9	-0.1	0.9	0.3	0.8	0.8	0.3	-0.5	-1.3	1.6	1.7
Medication: Seretide 50 evohaler	1.0	1.2	3.8	1.5	1.6	1.2	0.3	0.4	1.4	-0.1	1.0	1.3	0.6	0.1	1.9	0.1	1.8	0.2	-0.8	-0.5	0.5	1.9
Hypertension (Self-reported)	1.0	2.7	9.7	-1.5	-0.2	0.5	2.1	1.3	-0.2	-3.1	-1.4	-2.9	-1.4	-1.9	-0.7	-1.8	-0.8	0.2	0.1	2.6	-2.2	-1.9
Leg fat-free mass (right)	1.0	5.3	18.0	-4.2	-3.1	-2.6	-0.9	0.1	-2.8	-1.6	-3.0	-3.1	-3.8	-0.2	-1.9	0.2	-3.5	0.2	1.7	1.7	-1.7	-1.7
Leg predicted mass (right)	1.0	5.1	17.2	-4.2	-3.1	-2.5	-0.9	0.1	-2.8	-1.6	-2.9	-3.0	-3.8	-0.2	-1.9	0.2	-3.4	0.1	1.7	1.6	-1.7	-1.7
Medication: Bendroflumethiazide	1.0	1.6	6.4	-1.2	0.1	0.5	1.4	1.9	-0.1	-1.6	-0.7	-2.5	-1.3	-1.5	-0.4	-1.5	-0.8	0.3	0.0	2.5	-0.6	-1.3
Worry (Nagel 2018)	0.9	1.9	4.5	-1.9	-1.8	-1.8	-0.6	-1.1	-1.8	0.1	-1.1	-1.0	-1.4	0.7	-1.5	0.5	-2.1	0.2	1.9	1.3	-1.3	-1.8
Major Depression (MDD)	0.9	1.1	5.1	1.2	0.1	0.3	0.7	-0.3	0.5	1.1	2.2	1.6	1.5	0.6	1.0	0.7	1.3	1.4	-0.3	-0.2	0.8	1.3
Coronary Artery Disease (CAD)	0.9	1.1	4.7	-1.2	-0.4	-1.3	-2.2	-0.8	-1.2	1.1	-0.2	0.6	1.6	1.1	0.6	1.5	-0.3	1.4	0.7	-0.2	0.0	0.9
HbA1C	0.9	1.0	3.9	-1.3	-0.6	0.9	-0.3	-0.4	-0.1	-0.8	-1.8	-1.7	-0.3	-0.8	-1.2	-0.6	-1.2	-0.4	-0.0	0.4	-1.3	-2.0
Triglycerides	0.9	1.6	4.4	0.3	1.1	1.4	2.1	0.6	1.0	-1.0	-0.9	-1.7	-1.2	-1.9	-1.1	-1.9	-0.4	-1.0	-1.4	0.5	-1.5	-1.4
Hand grip strength (right)	0.9	2.5	6.5	-1.2	-1.8	-2.1	-1.7	-1.0	-2.1	2.6	1.2	0.8	0.3	2.0	0.9	2.4	-0.8	1.9	1.6	-0.0	2.2	1.0
Average weekly fortified wine intake	0.9	1.1	4.0	-0.4	0.6	0.4	1.2	-0.3	0.3	-2.0	-1.5	-1.7	0.1	-0.7	-1.8	-1.0	-0.8	-0.6	0.1	0.7	-1.9	-1.0
Stomach or abdominal pain in last month	0.9	1.2	4.6	-0.3	-0.4	0.4	0.5	-1.3	0.3	-2.1	-1.4	-0.9	-1.8	-1.4	-1.2	-1.3	-0.0	-1.5	-0.9	-0.7	-1.2	-0.6
Impedance of leg (left)	0.9	4.2	11.9	3.5	2.2	1.7	0.7	-1.0	2.2	1.4	3.3	3.0	3.2	0.8	2.0	0.3	2.9	-0.3	-1.5	-2.2	1.6	1.7
Waist circumference	0.9	3.2	10.7	-3.3	-2.4	-2.3	-1.5	0.2	-2.5	-1.6	-1.6	-1.6	-3.1	0.8	-0.2	1.2	-2.5	1.0	1.8	1.5	0.1	-0.5
Medication: Ramipril	0.9	1.1	3.0	0.4	1.4	1.1	1.6	1.5	1.0	-1.7	-0.6	-1.7	-0.5	-0.9	-0.5	-1.4	-0.3	-1.3	-1.0	0.5	-0.7	-0.8
Serious illness, injury or assault of a close relative in last 2 years	0.9	1.0	3.8	-0.7	-1.2	-0.9	-1.1	-2.0	-1.0	1.6	-0.4	1.1	-0.2	1.1	-0.2	1.4	-0.9	0.6	0.5	-1.1	1.1	0.6
Seen a psychiatrist for nerves, anxiety, tension or depression	0.9	1.2	4.8	0.3	-0.2	-0.5	-0.7	0.9	-0.3	-0.3	0.8	1.0	2.2	1.1	1.4	1.1	0.8	1.8	1.3	1.2	0.8	1.7
Number of children fathered	0.9	1.1	4.4	1.2	-1.1	-0.7	-0.7	2.1	-0.2	0.9	1.0	1.1	0.3	1.9	1.1	1.3	0.6	0.4	1.2	0.6	1.1	0.3
Whole body fat mass	0.9	3.9	13.1	-3.6	-2.8	-2.6	-1.3	-0.2	-2.8	-2.0	-1.9	-2.1	-3.0	0.5	-1.0	0.9	-3.2	0.5	1.8	1.3	-0.4	-1.2
Leg fat mass (right)	0.9	3.6	11.5	-3.4	-2.9	-2.4	-1.1	-0.4	-2.6	-1.4	-2.1	-2.2	-2.7	0.5	-1.4	0.8	-3.0	0.7	1.7	1.6	-0.3	-1.2
Leg pain on walking	0.9	1.1	3.8	1.2	1.7	1.5	1.9	0.8	1.5	0.2	0.6	0.5	-0.4	-0.9	0.8	-1.0	1.1	-0.6	-1.3	-1.0	-1.2	0.2
Arm fat percentage (left)	0.9	3.5	12.0	-3.5	-2.2	-2.2	-1.2	0.5	-2.7	-2.7	-1.9	-2.1	-2.8	0.4	-0.4	0.8	-3.0	0.9	1.7	1.6	-0.2	-0.9
Osteoarthritis (self-reported)	0.9	1.2	4.9	-1.0	-0.5	-0.2	-0.1	-1.1	-0.2	0.0	-1.5	-2.2	-1.2	-0.6	-1.9	-0.7	-1.5	-0.8	-0.3	0.6	-1.1	-1.9
Hearing aid user	0.9	1.0	4.9	1.2	-0.1	-0.6	-1.1	-0.5	0.0	2.2	0.7	1.2	1.8	1.2	1.2	0.7	0.6	-0.9	-0.1	-1.4	0.4	0.2
Medication: Lisinopril	0.9	1.2	8.9	-1.2	0.0	0.5	1.0	1.6	-0.2	-0.7	-0.6	-2.0	-0.8	-1.2	-0.1	-1.0	-0.3	1.2	0.4	3.0	-0.2	-0.4
Basal metabolic rate	0.9	4.9	18.0	-4.2	-3.2	-2.5	-1.0	-0.4	-2.9	-1.2	-2.8	-2.9	-3.3	-0.2	-2.2	0.4	-3.3	0.6	1.7	1.8	-1.1	-1.3
Commuting to job workplace: Cycle	0.9	1.1	5.8	1.0	0.4	0.2	0.4	1.2	0.4	0.3	2.0	1.6	2.4	0.5	1.4	0.3	1.6	0.3	0.3	0.2	0.5	0.7
Leg fat mass (left)	0.9	3.4	11.0	-3.3	-2.7	-2.3	-0.9	-0.1	-2.5	-1.6	-1.9	-2.4	-2.6	0.4	-1.4	0.7	-2.9	0.6	1.6	1.6	-0.5	-1.2
Schizophrenia vs Biploar Disorder	0.8	1.1	3.6	1.3	1.4	0.7	0.1	0.1	0.9	1.3	1.9	1.6	1.9	0.7	0.7	0.3	1.0	-0.3	-0.6	-0.8	0.7	1.2
Body Mass Index (BMI) (2010)	0.8	1.1	4.5	-1.3	-0.3	-0.0	0.5	-0.1	-0.7	-1.0	-1.5	-1.9	-0.2	-1.2	-2.1	-0.8	-1.3	0.3	0.2	1.4	-0.4	-1.3
Crohns Disease (2012)	0.8	1.3	4.0	-1.6	-1.1	-1.3	-0.3	0.3	-1.6	-1.8	-1.1	-1.3	-0.7	0.6	-0.6	0.7	-2.0	0.7	1.2	1.5	-0.8	-1.1
Cardiovascular Disease	0.8	2.7	8.9	-0.3	0.7	1.3	2.6	1.0	0.7	-3.0	-1.0	-2.4	-1.2	-2.5	-0.8	-2.4	0.1	-0.7	-0.9	1.4	-2.7	-1.8
Chronotype (morning person)	0.8	2.0	8.1	-1.9	-1.0	-2.0	-1.9	-1.7	-1.8	2.8	-0.6	0.0	0.6	1.4	-0.3	1.8	-1.8	0.7	1.4	-0.9	0.6	0.2
Medication: Metformin	0.8	1.2	4.1	1.1	0.7	0.8	1.1	0.8	1.3	-1.6	-0.5	0.1	-1.0	-0.9	0.9	-1.5	1.6	-2.0	-1.1	-0.5	-1.3	0.3
Pack years adult smoking proportion	0.8	1.2	5.8	1.1	-0.9	-0.1	0.1	0.3	0.3	2.4	0.6	0.9	-0.2	0.4	1.2	0.4	1.8	-0.1	-0.6	-1.2	2.1	1.7
Impedance of leg (right)	0.8	3.7	9.7	3.1	1.8	1.5	0.4	-1.7	1.8	2.0	2.9	3.0	2.7	0.8	1.5	0.5	2.7	-0.1	-1.4	-2.2	2.1	1.6
High blood pressure	0.8	2.1	7.1	-1.7	-0.9	-0.2	1.6	1.2	-0.8	-2.5	-1.4	-2.7	-1.2	-1.2	-0.5	-1.1	-1.1	0.6	0.8	2.6	-1.6	-1.7
Body mass index (BMI)	0.8	3.2	10.8	-3.3	-2.1	-1.9	-0.7	0.5	-2.2	-2.1	-2.3	-2.6	-2.3	-0.1	-1.3	0.3	-2.8	0.8	1.6	2.1	-0.7	-1.0
Arm fat percentage (right)	0.8	3.2	10.7	-3.3	-2.0	-2.0	-1.0	0.7	-2.4	-2.9	-1.9	-2.1	-2.5	0.1	-0.4	0.6	-2.8	0.7	1.5	1.7	-0.4	-1.1
Frequency of tiredness / lethargy in last 2 weeks	0.8	1.2	4.8	0.4	1.0	0.9	2.2	1.9	0.7	-1.6	0.1	-0.3	1.3	-1.2	1.1	-1.2	0.9	0.5	-0.1	1.6	-1.4	-0.1
Falls in the last year	0.8	1.1	3.2	0.3	1.0	1.2	1.4	-1.5	1.1	-1.3	-0.4	-0.8	-0.2	-1.8	-0.5	-1.7	0.4	-1.0	-1.4	-0.7	-1.2	-0.3
Seen doctor (GP) for nerves, anxiety, tension or depression	0.8	1.2	4.0	0.9	0.6	-0.1	-0.3	1.2	-0.1	-0.2	2.0	1.7	1.5	1.6	1.6	1.2	0.1	1.6	1.0	1.1	0.9	0.9
Glaucoma (self-reported)	0.8	0.9	3.9	0.0	0.9	1.0	1.5	0.1	0.9	-2.0	0.0	-0.5	0.1	-1.1	-1.0	-1.3	-0.0	-1.2	-0.5	-0.6	-1.4	-1.0
Medication: Amlodipine	0.8	1.1	6.5	-0.7	0.3	0.6	2.5	1.6	0.0	-1.3	-0.6	-1.7	-0.1	-1.6	-1.1	-1.2	-0.1	-0.2	-0.7	0.3	-0.9	-0.9
Medication: Ventolin 100micrograms inhaler	0.8	1.1	3.3	1.3	1.8	1.0	0.1	-1.2	1.6	-0.0	0.4	0.9	0.9	-0.2	0.4	-0.5	1.1	-1.1	-1.1	-1.7	-0.7	1.3
Commuting to job workplace: Car/motor vehicle	0.8	0.9	3.5	1.3	1.2	0.8	-0.2	-1.2	1.2	0.2	1.0	1.0	0.5	0.3	0.9	0.1	1.7	0.3	-0.8	-0.8	0.5	1.9
Whole body fat-free mass	0.8	4.5	16.5	-4.1	-3.1	-2.4	-1.0	-0.4	-2.7	-0.8	-2.8	-2.7	-3.2	-0.2	-2.2	0.3	-3.1	0.5	1.6	1.6	-1.1	-1.2
Whole body water mass	0.8	4.6	16.5	-4.1	-3.1	-2.3	-1.1	-0.5	-2.7	-0.8	-2.8	-2.8	-3.4	-0.3	-2.3	0.3	-3.2	0.4	1.6	1.5	-1.2	-1.2
Alcohol drinker status: Never	0.8	0.9	3.6	0.2	-1.3	-1.4	-0.7	0.3	-0.8	1.9	0.2	1.5	0.5	1.3	0.7	1.4	0.3	0.6	0.5	-0.7	1.6	0.5
Ever smoked	0.8	1.4	5.5	2.3	-0.1	0.3	0.3	1.0	0.7	-0.1	1.4	2.3	0.8	1.4	1.4	0.5	2.2	-0.1	0.3	-0.1	1.1	1.6
Schizophrenia (2018)	0.7	1.4	5.0	2.2	1.8	0.9	0.2	1.4	1.1	0.9	1.4	1.8	1.0	0.7	1.2	0.3	1.6	-0.4	-0.9	-1.0	0.7	1.4
Hand grip strength (left)	0.7	1.9	6.6	-0.3	-1.1	-1.4	-1.1	-0.9	-1.3	2.6	1.8	1.1	1.5	1.6	0.8	2.0	-0.2	1.7	0.8	-0.3	2.1	1.3
Trunk fat percentage	0.7	2.7	8.6	-2.9	-2.0	-2.1	-1.3	-0.2	-2.4	-2.4	-1.3	-1.7	-2.4	0.6	-0.3	0.8	-2.9	0.4	1.5	1.0	-0.2	-1.3
Maternal smoking around birth	0.7	0.9	3.8	-0.6	1.4	0.6	2.0	0.3	0.2	-0.6	-0.2	-1.0	1.6	-1.1	-1.4	-0.8	-1.2	0.1	-0.4	0.3	-1.4	-0.9
Taking other prescription medications	0.7	1.1	4.5	-1.5	-0.0	-0.2	0.6	0.3	-0.3	-1.0	-1.9	-2.1	-1.1	-0.8	-1.6	-0.7	-1.7	-0.7	0.2	-0.1	-1.5	-0.9
Age when periods started (menarche)	0.7	1.7	9.3	1.8	0.0	0.5	-0.9	-0.3	0.9	3.0	1.5	1.7	-1.0	1.2	1.5	1.0	1.4	0.1	-0.3	-1.8	1.2	1.1
Ever unenthusiastic/disinterested for a whole week	0.7	0.9	4.1	0.2	-0.6	-0.1	0.1	0.2	-0.5	-0.2	1.6	0.6	0.5	1.0	1.3	0.8	0.9	2.0	0.9	1.8	0.5	0.6
Fluid intelligence score	0.7	1.5	4.0	-1.0	-0.8	-1.5	-1.8	0.9	-1.4	-0.9	0.7	0.7	-0.9	1.5	2.0	1.7	-0.5	1.7	1.6	1.1	0.7	0.8
Trunk fat-free mass	0.7	4.1	15.1	-3.9	-3.2	-2.4	-1.2	-0.6	-2.7	-0.2	-2.5	-2.3	-2.8	0.1	-2.3	0.6	-3.0	0.8	1.7	1.5	-0.7	-0.9
Medication: Ibuprofen (e.g. Nurofen)	0.7	0.8	3.2	0.7	-0.1	0.1	-1.0	1.4	-0.3	0.5	1.2	1.1	-0.3	1.1	1.8	1.0	0.9	1.1	0.6	0.5	1.2	0.9
Pulse wave Arterial Stiffness index	0.7	0.9	4.0	-1.2	-0.4	-0.9	-0.4	-0.9	-0.9	-2.0	-0.1	-0.6	-0.8	-0.4	-1.5	-0.2	-1.8	-0.3	0.4	0.0	-0.2	-1.4
Trunk predicted mass	0.7	3.9	14.4	-3.8	-3.1	-2.3	-1.2	-0.7	-2.6	-0.2	-2.5	-2.3	-2.8	0.1	-2.2	0.6	-2.8	0.7	1.6	1.4	-0.7	-0.9
Hair/balding pattern: Pattern 4	0.7	1.6	6.8	-1.1	0.1	0.4	1.3	1.3	0.0	-1.6	-0.9	-2.2	0.2	-1.4	-1.0	-1.4	-0.8	0.3	0.5	2.6	-1.7	-1.7
Mouth/teeth dental problems: Bleeding gums	0.7	0.9	5.1	-0.0	1.6	0.9	0.9	-0.2	0.7	-0.6	0.0	-0.6	1.1	-2.3	-0.7	-1.5	0.7	-0.1	-1.4	-0.6	-1.1	0.1
High blood pressure (siblings)	0.7	1.0	2.3	0.9	1.5	1.2	1.1	-1.4	1.2	0.4	-0.2	0.2	1.2	-1.3	-1.0	-1.1	0.5	-1.1	-1.5	-1.2	-0.2	0.6
Body fat percentage	0.7	2.8	8.8	-3.0	-2.2	-2.2	-1.2	-0.0	-2.4	-2.3	-1.5	-1.8	-2.4	0.7	-0.4	0.9	-2.8	0.5	1.6	1.3	-0.1	-1.1
Arm fat-free mass (right)	0.7	3.4	11.6	-3.4	-3.0	-2.3	-1.3	-0.7	-2.5	-0.3	-1.9	-2.2	-2.8	0.2	-2.1	0.6	-2.8	0.4	1.6	1.3	-0.7	-0.9
Medication for pain relief, constipation, heartburn	0.7	1.1	3.7	-0.9	-0.7	-1.9	-1.4	-0.3	-1.3	1.3	0.5	1.3	1.0	1.6	0.8	1.6	-0.5	0.3	1.4	-0.7	0.3	0.7
Heart disease (mother)	0.7	0.8	3.5	0.4	0.8	0.7	1.6	1.9	0.6	-0.1	-1.0	-1.1	-0.6	-1.3	-0.4	-1.3	0.1	-0.8	-1.0	0.3	-0.6	-0.6
Arm predicted mass (right)	0.7	3.8	13.0	-3.6	-3.1	-2.4	-1.3	-0.9	-2.6	-0.4	-2.1	-2.4	-2.8	0.2	-2.1	0.6	-2.9	0.6	1.8	1.5	-0.7	-0.9
Alcohol intake frequency.	0.7	1.5	4.8	-1.8	-1.7	-1.5	-1.2	-2.2	-1.3	1.1	-1.6	-1.2	-1.9	0.4	-1.1	0.7	-1.8	-0.1	0.4	-0.5	0.3	-0.5
Overall health rating	0.7	1.5	6.6	0.7	0.7	1.5	2.6	0.3	1.4	-0.7	-0.9	-1.2	-0.1	-2.1	-0.1	-2.1	1.0	-1.1	-1.7	-0.3	-1.2	-0.2
Guilty feelings	0.7	1.1	2.6	0.3	-0.5	-0.6	-1.5	0.8	-0.2	0.9	1.6	1.5	0.1	1.6	1.4	1.3	1.1	1.0	1.4	0.3	0.3	1.2
Mother’s age at death	0.7	0.8	3.0	-0.1	-1.3	-1.2	-1.5	-0.9	-0.7	0.3	0.6	0.8	-1.7	1.2	-0.1	1.2	-0.9	0.7	1.1	0.3	0.8	0.1
Tinnitus: Yes, now most or all of the time	0.7	0.9	3.6	-0.2	-0.8	-0.1	-0.2	-1.9	-0.1	-1.4	-1.7	-1.0	-0.0	-0.2	-1.6	-0.3	-1.3	-0.8	-0.1	0.3	-0.6	-1.3
Supplements: Fish oil (including cod liver oil)	0.7	0.9	4.1	2.0	1.0	0.8	0.0	-0.8	1.2	0.8	0.5	1.2	1.3	-0.1	0.2	-0.6	1.0	-1.3	-1.0	-1.2	0.4	0.2
Arm fat-free mass (left)	0.7	3.6	12.4	-3.5	-2.7	-1.8	-0.6	-0.5	-2.2	-0.9	-2.5	-2.8	-2.6	-0.4	-2.4	0.0	-2.9	0.3	1.3	1.6	-1.1	-1.2
Vascular/heart problems diagnosed by doctor	0.7	1.9	7.3	1.5	0.8	-0.1	-1.8	-1.3	0.6	2.1	1.4	2.7	1.6	1.3	0.6	1.1	1.0	-0.4	-0.4	-2.2	1.2	1.5
Heart disease (siblings)	0.7	0.9	4.2	-0.9	-1.1	-1.3	-2.1	-0.7	-1.1	0.8	0.4	0.3	1.0	1.2	0.3	1.4	-0.0	0.3	0.8	-0.6	0.7	1.0
Pack years of smoking	0.7	1.0	6.4	1.1	-0.8	-0.1	0.1	0.2	0.3	2.5	0.4	0.7	-0.4	0.4	0.9	0.3	1.6	-0.3	-0.7	-1.2	2.0	1.5
Arm predicted mass (left)	0.7	3.6	13.3	-3.6	-2.7	-1.9	-0.6	-0.5	-2.2	-0.8	-2.4	-2.8	-2.4	-0.4	-2.4	0.0	-2.9	0.5	1.5	1.9	-1.2	-1.2
Depressed Affect (Nagel 2018)	0.6	1.4	4.7	-1.3	-0.4	-0.7	0.1	1.0	-0.8	-0.8	-0.7	-1.3	-2.1	-0.5	-1.0	-0.6	-1.4	0.3	1.4	1.7	-2.2	-1.6
Reaction Time	0.6	1.2	4.4	1.7	0.9	1.1	0.9	0.2	1.8	-1.4	-0.1	-0.3	1.0	-1.0	-0.7	-1.6	0.8	-2.1	-1.5	-0.5	0.2	-0.1
Age at First Birth	0.6	0.8	2.0	-0.3	-0.8	-1.0	-1.3	1.1	-1.1	-0.2	0.6	0.2	0.6	1.2	1.3	1.1	0.0	1.0	1.4	1.3	1.0	0.0
Mean Putamen Volume	0.6	0.7	2.8	0.4	0.6	0.7	1.1	-0.3	0.8	-0.5	0.3	0.0	-0.4	-1.7	-0.7	-1.4	0.8	-1.0	-1.7	-1.1	0.1	-0.6
Lupus	0.6	0.9	4.5	0.9	0.7	1.7	0.4	0.7	1.7	-0.2	0.2	0.5	0.3	-0.7	1.1	-0.9	2.1	-0.5	-1.1	-0.4	-0.4	0.7
Rheumatoid Arthritis	0.6	0.9	3.6	-0.3	-0.5	-0.7	-1.2	-1.3	-0.2	1.9	1.3	1.0	1.8	0.7	0.7	0.6	0.4	-0.3	0.6	-0.9	-0.1	-0.7
Medication for hormone replacement therapy	0.6	0.7	3.6	0.5	-1.1	-0.3	-0.5	-0.6	-0.1	0.3	1.3	1.9	0.3	1.4	0.2	1.3	-0.2	0.4	0.7	-0.9	0.8	0.6
Medication: Co-codamol	0.6	0.7	2.9	-1.7	-1.5	-1.1	-0.4	1.1	-1.2	1.2	-0.8	-1.2	-0.5	0.2	-0.0	0.3	-0.5	-0.1	1.0	0.1	-0.4	-0.5
Fed-up feelings	0.6	1.0	3.0	-1.5	-1.2	-0.9	0.1	0.2	-1.2	-0.7	-1.3	-1.4	-1.1	-0.5	-1.0	-0.5	-1.2	0.0	1.0	1.0	-1.7	-1.3
High blood pressure (mother)	0.6	0.8	5.4	-0.0	0.5	0.1	0.9	2.3	0.3	-1.3	0.7	-0.7	-0.5	-0.6	0.9	-0.7	0.4	0.1	0.3	1.2	-1.6	-0.5
Number of incorrect matches in round	0.6	1.0	3.3	1.8	1.4	1.2	0.2	0.0	1.5	-0.1	1.7	1.0	0.8	-0.6	0.7	-1.0	1.2	-1.1	-0.8	-0.3	-0.5	-0.4
Had other major operations	0.6	0.8	2.9	-0.7	0.4	0.7	1.2	0.1	0.2	-1.3	-0.7	-1.2	0.6	-1.7	-0.4	-1.4	-0.5	-0.6	-0.6	-0.1	-0.8	-1.4
Medication: Cholesterol lowering	0.6	1.0	3.7	0.6	1.0	0.7	1.3	1.4	0.7	-1.1	0.5	-0.6	-0.6	-1.0	-0.3	-1.3	-0.4	-1.6	-0.8	-0.5	-1.4	-1.9
Medication: Lansoprazole	0.6	0.7	1.7	0.6	0.9	0.8	0.9	-0.6	1.3	-1.1	0.2	0.7	0.8	-0.8	0.2	-0.9	1.2	-1.0	-1.1	-0.9	-0.6	0.3
Lung cancer (father)	0.6	0.7	5.9	-0.2	-0.6	-0.2	0.7	1.2	0.4	-2.4	-0.9	-0.5	-1.8	0.3	0.2	-0.0	-0.1	-0.5	0.0	0.2	-1.0	0.1
Ever highly irritable/argumentative for 2 days	0.6	0.7	3.6	1.2	0.3	0.3	-0.1	1.5	0.7	-0.4	1.1	1.1	0.0	0.6	1.9	0.2	1.0	0.4	0.2	0.9	0.7	0.8
Headache pain in last month	0.6	1.0	3.5	-1.2	-0.4	-0.3	0.2	-1.3	-0.4	-0.1	-1.4	-1.2	-1.9	-0.5	-1.8	-0.2	-1.4	-0.8	-0.5	-1.2	-0.8	0.3
Chronic bronchitis/emphysema (mother)	0.6	0.6	2.5	0.5	0.3	0.6	0.6	-0.7	0.9	-0.4	-0.4	-0.5	-0.1	-0.6	-0.8	-0.9	0.2	-1.6	-0.9	-1.6	-1.5	-0.2
Leg fat percentage (right)	0.6	2.0	6.0	-2.4	-2.2	-1.8	-0.8	-0.7	-1.9	-1.4	-1.5	-1.7	-1.9	0.3	-1.2	0.6	-2.2	0.6	1.3	1.2	-0.0	-0.9
Wheeze or whistling in the chest in last year	0.6	1.0	3.0	1.2	0.7	0.9	1.3	0.6	1.4	-0.2	0.4	0.9	1.0	-0.6	1.4	-0.8	1.7	-1.1	-1.2	-1.4	-0.4	0.5
Pulse wave peak to peak time	0.6	0.7	4.0	1.0	0.4	0.8	0.3	0.9	0.8	2.0	-0.1	0.4	0.6	0.3	1.4	0.1	1.5	0.2	-0.3	0.0	0.1	1.3
Shortness of breath walking on level ground	0.6	0.7	2.6	0.9	0.9	0.8	0.7	-0.8	0.9	-0.5	1.6	0.5	-0.4	-1.1	0.4	-1.1	1.3	-0.8	-1.2	-0.8	-0.7	-0.4
Qualifications: College or University degree	0.6	1.9	5.6	-1.4	-0.5	-1.5	-1.5	1.8	-1.9	-1.5	0.5	-0.0	0.4	1.4	0.9	1.4	-1.9	1.5	2.3	2.4	0.3	-0.4
Medication: Blood pressure	0.6	1.1	4.0	0.0	0.6	1.0	1.6	1.6	0.4	-1.1	0.1	-1.2	0.1	-1.3	-0.2	-1.6	-0.1	-0.5	-0.3	1.5	-1.2	-2.0
Migraine (self-reported)	0.6	0.8	4.9	-1.0	-0.9	-0.4	1.4	1.0	-0.6	-2.2	-0.3	-1.2	-0.6	-0.1	-0.8	0.1	-1.2	0.6	0.7	0.8	0.1	-0.3
Comparative height size at age 10	0.6	3.5	10.3	-3.2	-2.9	-2.4	-1.2	-1.1	-2.3	-1.8	-2.4	-2.3	-2.0	0.4	-1.4	0.4	-3.0	-0.6	1.4	1.1	-1.2	-1.7
Age at last live birth	0.6	0.9	5.0	0.4	-0.3	-0.9	-0.9	-0.1	-0.8	-0.1	1.0	1.4	-0.0	2.2	1.2	1.7	-0.1	0.6	1.5	0.3	0.6	0.5
Illness, injury, bereavement, stress in last 2 years	0.6	0.7	3.0	-0.1	0.3	-0.3	0.0	0.6	0.1	-0.1	-1.3	-1.7	-0.4	0.0	-1.1	-0.5	-0.8	-0.4	0.4	1.7	-1.6	-0.5
Mood swings	0.6	1.2	5.6	-1.5	-0.5	-0.2	0.4	0.2	-0.7	-0.7	-1.4	-1.4	-1.0	-0.7	-1.2	-0.7	-1.8	0.2	0.9	1.3	-2.4	-1.1
Diabetes diagnosed by doctor	0.6	1.0	4.3	0.5	0.6	0.6	1.0	-0.1	1.0	-1.3	-0.3	-0.7	-1.7	-1.0	-0.1	-1.5	0.7	-2.1	-1.2	-0.5	-0.8	-0.8
Back pain experienced in last month	0.6	0.9	3.6	-1.0	-1.5	-0.7	0.3	1.3	-0.9	0.4	-1.9	-1.5	-0.4	0.3	-0.1	0.3	-0.6	1.2	0.9	1.6	0.2	0.5
Miserableness	0.6	1.1	6.2	-0.3	0.5	-0.0	0.7	2.1	0.0	-0.7	0.0	-1.2	-0.3	-0.5	-0.1	-0.9	-0.6	0.1	1.1	1.9	-2.5	-1.2
Medication: Paracetamol	0.6	1.0	4.3	-0.3	-0.3	0.8	0.7	-0.6	0.4	-0.8	-1.7	-2.1	-1.8	-1.3	-1.4	-1.1	-0.4	-0.3	-0.5	0.7	-1.0	-0.7
Irritability	0.6	1.0	4.2	-0.9	-0.5	-0.5	-0.9	1.6	-0.9	0.8	0.2	-0.2	-1.1	0.7	0.6	0.7	-0.7	1.8	1.6	2.1	-0.1	0.3
Risk taking	0.6	0.9	1.9	0.2	0.9	1.2	1.3	1.0	0.6	-1.3	-1.1	-1.4	0.7	-1.2	-0.8	-1.2	-0.1	0.2	-0.6	1.1	-0.8	-0.5
Ever depressed for a whole week	0.6	0.8	3.6	-0.7	-0.7	-0.8	-0.5	-0.8	-1.1	-0.1	1.0	0.1	0.7	0.9	0.8	1.0	-0.1	1.9	1.4	1.3	0.6	0.5
Supplements: Calcium	0.6	0.7	3.3	1.3	0.7	0.8	0.7	0.1	0.9	-0.6	-0.5	0.1	1.3	-0.5	-0.6	-1.0	0.3	-1.8	-1.1	-1.0	-0.2	-0.3
Intelligence (Savage-Jansen 2018)	0.5	1.5	5.1	-1.1	-0.7	-1.3	-2.3	-0.1	-1.3	-1.3	0.1	0.5	-2.1	1.2	1.4	1.5	-1.0	1.6	1.5	0.9	0.8	0.4
Alzheimer’s Disease (including proxy)	0.5	0.7	2.2	-1.1	0.1	0.4	1.0	0.2	-0.4	-1.5	-1.5	-1.0	1.0	-0.6	-0.7	-0.1	-0.4	1.4	0.2	1.4	0.1	0.6
Verbal and Numeric Reasoning (VNR)	0.5	1.2	3.9	0.3	-0.5	-0.8	-1.7	0.2	-0.5	-1.0	1.1	1.5	-1.4	1.8	2.0	1.7	0.2	1.2	0.9	0.1	0.8	1.0
Bipolar Disorder (2011)	0.5	0.5	3.6	0.1	-0.3	-0.3	-0.1	1.9	-0.3	-0.7	0.1	0.4	-0.5	0.9	1.4	0.7	-0.3	0.7	0.6	0.7	-0.2	-0.7
Schizophrenia (2014)	0.5	1.1	4.9	1.4	1.3	0.7	0.6	2.2	0.6	0.1	1.3	1.4	1.6	0.4	1.5	0.0	1.2	0.0	-0.2	0.1	0.1	0.8
Blood White Count	0.5	3.6	11.8	0.6	-0.8	-1.1	-2.0	-0.9	-0.6	1.4	3.0	3.0	-0.0	2.0	3.4	2.3	1.9	2.0	0.7	-0.4	2.8	2.8
Lung FEV1/FVC ratio	0.5	2.6	14.3	-1.6	-1.6	-1.7	-2.1	-2.6	-1.5	0.1	-1.7	-0.4	-3.8	1.0	-1.8	1.0	-2.2	-0.7	0.6	-0.5	-0.3	-1.0
Sensitivity / hurt feelings	0.5	0.8	4.2	0.5	0.8	0.3	-0.8	-0.8	0.3	0.1	1.2	1.6	0.0	0.3	1.7	0.6	1.2	1.2	0.0	0.0	0.8	2.0
Ever had hysterectomy (womb removed)	0.5	0.6	4.7	-0.1	-0.1	0.6	-0.2	-1.8	0.5	-2.2	-0.2	-0.5	-0.5	-0.8	-0.2	-0.7	0.4	-0.6	-0.9	-0.1	-0.5	0.1
Angina	0.5	0.6	1.7	1.2	1.0	0.9	0.5	0.9	1.3	-0.5	0.7	0.6	0.2	-0.2	1.0	-0.5	1.1	-0.7	-0.9	-0.6	0.1	0.8
Diabetes (father)	0.5	0.6	2.2	0.5	1.2	1.0	0.6	-1.5	1.1	0.1	1.1	0.1	0.3	-0.8	-0.6	-0.8	0.6	-0.3	-1.4	-0.4	0.5	-0.3
Had menopause	0.5	0.7	2.4	0.5	-0.4	-0.0	-0.7	-1.5	0.3	1.1	0.1	0.9	1.0	0.7	0.9	0.6	0.7	-0.4	-0.6	-1.1	1.5	1.1
Financial difficulties in last 2 years	0.5	0.7	2.6	0.1	0.5	1.3	1.3	0.4	0.5	-1.3	-0.3	-0.6	-1.0	-1.6	0.4	-1.1	0.6	-0.3	-1.2	-0.7	-0.0	-0.1
Medication: Simvastatin	0.5	0.7	3.0	0.9	1.1	0.7	1.4	1.7	1.2	-0.7	0.6	-0.2	0.5	-0.1	0.9	-0.7	0.6	-0.9	-0.4	0.3	-1.2	0.0
Illnesses of siblings	0.5	0.7	2.4	-0.5	-0.9	-0.8	-0.3	1.5	-0.8	0.1	0.1	-0.1	-0.2	1.1	0.9	1.0	-0.3	1.5	1.2	1.4	0.7	0.4
Alcohol intake versus 10 years previously	0.5	0.7	2.7	-0.9	-1.0	-1.3	-1.6	-0.6	-0.9	1.0	0.0	-0.3	-1.7	0.6	0.0	0.8	-0.6	-0.2	0.5	-0.8	0.1	-0.5
Worrier / anxious feelings	0.5	1.0	2.6	-1.4	-1.2	-1.6	-1.1	-0.5	-1.4	1.0	-0.4	-0.6	-0.9	0.5	-0.7	0.4	-1.5	0.2	1.5	0.7	-0.7	-0.7
Qualifications: A levels/AS levels or equivalent	0.5	1.1	4.8	-1.5	-0.3	-0.5	0.1	2.2	-1.1	-1.6	-1.1	-1.3	-2.0	-0.2	-0.3	-0.0	-1.4	0.5	0.7	1.1	-0.4	-0.7
Depression (self-reported)	0.5	0.6	3.2	-0.5	-0.3	-0.6	-1.1	-0.2	-0.9	-0.9	0.0	-0.1	-0.5	0.8	0.5	0.7	-0.9	1.1	1.4	1.8	0.0	-0.2
Forced expiratory volume in 1-second (FEV1), Best measure	0.5	1.7	4.4	-1.8	-2.1	-1.9	-0.7	-0.6	-2.1	1.4	-0.7	-0.8	0.2	1.1	-1.3	1.1	-1.7	1.2	1.9	1.5	-0.2	-0.8
Pulse wave reflection index	0.5	0.6	2.2	-1.0	-0.6	-0.7	-0.2	-0.5	-1.0	-0.4	-0.9	-0.9	0.3	-0.6	-1.1	-0.5	-1.1	-0.3	0.4	0.5	-0.8	-1.5
Gout (self-reported)	0.5	0.7	4.0	0.6	1.2	1.0	0.5	2.0	1.0	-1.0	0.2	-0.5	-0.1	-0.1	0.8	-0.5	0.9	0.1	-0.1	1.5	-0.7	0.9
Medication: Omeprazole	0.5	0.6	1.7	0.0	1.0	1.0	0.6	-0.1	0.9	0.1	-0.3	-1.1	0.2	-1.2	-0.7	-1.3	0.7	-0.8	-0.7	-0.1	-1.3	-0.6
Mean time to correctly identify matches	0.5	1.0	5.2	1.2	0.6	0.7	0.1	-0.8	1.4	-0.8	-0.7	-0.5	0.9	-0.9	-1.2	-1.4	0.2	-2.3	-1.4	-0.9	0.2	-0.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.5	0.6	1.9	-1.0	-1.4	-1.4	-0.4	0.1	-1.3	0.2	0.9	0.2	-0.0	0.7	0.3	1.1	-0.4	1.1	0.7	0.3	1.0	-0.1
Suffer from ‘nerves’	0.5	0.8	3.2	-0.9	-1.8	-1.3	-0.5	-0.7	-1.3	1.2	0.1	0.7	-0.9	0.9	-0.5	0.9	-1.1	0.4	1.3	-0.4	-0.0	-1.1
Family relationship satisfaction	0.5	0.6	3.1	-0.6	-0.7	-0.9	-1.8	-0.8	-1.1	0.3	0.5	0.6	-0.5	1.1	0.2	1.1	-0.5	0.5	1.2	0.3	-0.3	-0.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.5	0.6	2.1	-1.2	-1.3	-1.5	-0.7	-0.9	-1.1	-0.4	-0.6	-0.1	0.8	0.7	-0.5	0.7	-0.8	-0.2	0.9	0.0	-0.1	-0.6
Smoking status: Previous	0.5	0.7	3.3	1.0	0.5	1.0	0.9	1.1	1.0	-1.8	-0.9	-0.1	0.2	0.0	-0.6	-0.8	0.4	-0.4	0.2	1.6	-0.8	0.1
Loneliness, isolation	0.5	0.7	2.5	-0.3	-0.6	-1.1	-0.2	0.9	-0.9	1.6	1.2	1.5	-0.3	0.8	0.7	0.9	-0.2	0.3	0.7	-1.2	0.1	0.0
Ever had bowel cancer screening	0.5	0.6	2.1	-0.8	-1.3	-0.9	-0.7	-0.2	-1.0	0.3	-1.3	-0.2	0.4	0.4	-1.0	0.3	-0.9	-0.1	0.8	0.8	0.2	-1.5
Mineral and other dietary supplements	0.5	0.7	3.0	-0.3	-0.3	-0.2	-0.3	0.7	-0.2	-0.1	1.3	0.7	-0.8	0.9	1.6	1.1	0.7	1.4	0.4	-0.0	0.5	1.7
Osteoporosis (self-reported)	0.5	0.7	3.4	0.4	-0.1	-0.2	0.3	-0.3	0.4	0.6	-0.5	-0.3	-1.4	-0.0	-0.9	-0.4	-1.0	-1.9	-0.6	-1.8	0.2	-1.2
Medication: Gliclazide	0.5	0.6	1.4	0.6	0.8	0.7	0.9	0.1	0.8	-0.2	0.6	0.5	-0.9	-0.8	0.6	-0.7	1.2	-0.9	-1.2	-1.1	0.6	0.2
Number of self-reported non-cancer illnesses	0.5	0.9	4.9	-0.7	-0.1	0.2	0.8	0.7	-0.1	-1.9	-1.2	-2.2	-1.7	-0.7	-0.4	-0.7	-0.6	0.3	0.1	1.6	-0.3	0.0
Commuting to job workplace: Public transport	0.5	0.5	1.9	-0.5	-1.4	-1.4	-1.3	-0.2	-1.1	0.7	0.0	0.2	-0.3	0.8	-0.2	0.7	-0.7	-0.3	1.1	-0.0	0.2	-0.7
Age started oral contraceptive pill	0.5	0.6	2.6	-0.7	-1.1	-0.8	-0.8	-0.5	-0.6	1.6	-0.4	-0.1	0.4	0.8	0.6	1.0	-0.4	0.3	0.4	-0.7	1.6	0.7
Basal cell carcinoma (self-reported)	0.5	0.7	2.4	0.3	0.3	0.7	0.7	-0.1	0.9	-1.1	-0.2	0.1	-1.1	-0.7	0.1	-0.8	0.1	-1.6	-1.2	-1.3	-1.0	-1.0
Impedance of whole body	0.5	2.5	7.0	2.6	1.8	1.1	0.1	-0.7	1.4	0.5	2.5	2.6	2.0	1.0	2.2	0.6	2.0	-0.5	-1.1	-2.2	1.6	1.0
Bipolar Disorder or Schizophrenia	0.4	1.0	4.3	2.1	1.8	0.7	0.3	1.4	0.9	0.2	1.1	1.8	0.4	0.8	1.2	0.2	1.1	-0.3	-0.5	-0.6	0.8	0.6
Neuroticism (Nagel 2018)	0.4	1.0	3.9	-1.0	-0.8	-1.3	-0.9	0.2	-1.2	0.7	0.5	0.1	-1.8	0.8	0.1	0.7	-1.0	1.0	2.0	1.3	-0.9	-0.4
HDL Cholesterol	0.4	0.6	2.7	-0.2	0.6	-0.1	0.1	0.0	0.2	-0.8	-0.4	-1.1	0.7	-0.8	-1.2	-1.0	-0.2	-1.7	-0.3	-0.4	-1.5	-1.1
Type 2 Diabetes (T2D) (2012)	0.4	0.5	1.7	-0.7	-0.8	-0.5	-0.8	-0.6	-0.9	0.7	1.0	0.3	0.4	0.4	0.8	0.8	0.2	1.3	0.8	0.6	0.8	0.3
Blood Red Count	0.4	4.0	10.0	-1.8	-1.8	-2.6	-2.7	-0.7	-2.3	3.1	1.7	1.5	0.1	2.8	1.5	3.2	-1.2	2.1	1.8	-0.2	2.8	1.4
BMI	0.4	2.5	6.4	-2.4	-1.6	-1.6	-1.2	0.2	-2.1	-2.4	-1.7	-2.2	-2.0	0.2	-1.0	0.5	-2.5	0.8	1.3	2.2	0.5	-0.5
Systolic Blood Pressure	0.4	1.9	6.0	-0.9	0.4	0.9	2.4	0.1	0.6	-1.5	-1.9	-2.5	1.0	-2.0	-1.3	-1.9	-0.4	-0.6	-0.6	1.0	-2.0	-1.5
Type 2 Diabetes (T2D) (2018)	0.4	0.8	3.2	0.7	0.4	0.8	1.2	0.9	1.1	-1.8	0.2	-0.4	-1.2	-0.7	0.2	-1.3	0.6	-1.2	-0.8	0.8	-0.7	-0.5
Neuroticism	0.4	1.0	3.3	-0.9	-1.2	-1.4	-0.7	0.9	-1.2	-0.1	0.5	-0.2	-1.6	0.9	0.3	0.6	-1.1	0.6	1.8	1.3	-1.0	-0.9
Hearing difficulty/problems: Yes	0.4	0.6	3.3	1.2	-0.1	0.8	0.3	-0.4	0.9	0.6	0.9	0.6	1.8	-0.2	-0.0	-0.5	0.7	-1.0	-0.5	-1.0	-0.2	-0.7
Bilateral oophorectomy (both ovaries removed)	0.4	0.4	2.0	0.4	0.2	0.6	0.6	1.4	0.5	-1.3	0.9	-0.3	0.2	-0.4	0.8	-0.4	0.8	0.5	0.2	1.0	-0.2	-0.1
Supplements: Glucosamine	0.4	0.5	1.9	0.5	0.6	0.6	0.4	0.3	0.6	-1.4	-0.7	-0.5	0.2	-0.5	-0.8	-0.9	-0.1	-0.7	-0.3	1.0	-0.7	-1.1
Heel bone mineral density (BMD) T-score, automated (right)	0.4	1.0	2.9	1.5	1.3	1.2	-0.0	0.9	1.6	-0.0	1.3	0.8	1.0	-0.6	1.2	-0.8	1.7	-0.5	-0.7	-0.1	-0.7	0.6
Mouth/teeth dental problems	0.4	0.7	3.5	-0.4	-0.6	-0.7	-0.9	0.6	-0.9	-0.7	-0.1	0.3	-1.9	1.4	0.2	1.1	-0.6	0.3	0.9	0.4	1.4	-0.0
Pain all over the body in last month	0.4	0.4	1.9	0.4	-0.2	0.5	0.9	0.7	0.8	-0.1	-0.2	0.1	0.4	-0.7	-0.6	-0.8	0.5	-1.4	-0.8	-1.1	0.0	-0.7
Neuroticism score	0.4	0.7	2.7	-1.1	-0.9	-1.0	-0.4	1.1	-1.0	-0.2	0.1	-0.3	-0.9	0.4	0.3	0.3	-0.8	0.7	1.6	1.3	-1.4	-0.6
Number of live births	0.4	0.5	3.2	-0.9	-0.1	-0.3	-0.3	-0.0	-0.6	0.1	0.9	0.3	1.0	0.6	1.1	1.0	-0.1	1.8	1.1	0.5	0.4	0.6
Pulse rate	0.4	0.7	2.7	0.3	0.8	1.2	1.6	0.8	1.3	-0.8	1.2	0.4	-0.1	-1.1	0.6	-1.0	1.0	-0.0	-1.1	-0.5	-0.3	0.1
Prospective memory result	0.4	0.5	3.7	0.2	-0.7	-0.2	-0.6	-0.6	0.4	0.6	0.2	0.0	0.8	0.2	-0.2	-0.4	-0.2	-1.3	0.2	-0.4	-1.9	-1.3
Standing height	0.4	3.7	11.5	-3.0	-3.4	-2.9	-2.3	-1.8	-2.8	1.1	-1.5	-0.6	-2.7	1.6	-1.1	1.8	-2.6	0.3	1.8	0.0	0.5	-0.7
Tense / ‘highly strung’	0.4	0.7	1.9	-1.3	-0.8	-0.8	-0.2	0.1	-0.8	-0.9	0.5	-0.6	-1.4	0.4	-0.3	0.3	-1.3	0.6	1.2	0.8	-1.3	-1.2
Medication: Paracetamol	0.4	0.7	2.8	-0.8	-0.7	0.4	0.1	-1.1	0.1	-0.1	-1.4	-1.7	-1.7	-0.9	-1.5	-0.5	-0.6	0.1	-0.4	-0.0	-0.4	-0.5
Number of full brothers	0.4	0.5	4.6	-0.3	-0.2	-0.4	0.1	-1.0	-0.5	0.5	0.8	0.6	2.1	0.2	-0.1	0.3	-0.1	-0.3	0.2	-0.9	-1.1	-0.1
Worry too long after embarrassment	0.4	0.7	2.7	0.8	-0.1	-0.7	-0.9	0.4	-0.6	1.2	1.2	1.2	0.8	1.2	1.6	0.9	0.7	0.6	0.7	0.5	0.8	0.5
Health satisfaction	0.4	0.5	2.1	-1.0	-0.2	0.0	1.2	0.2	-0.3	-0.4	0.1	-0.9	-1.3	-0.9	-0.4	-0.5	-0.2	-0.2	-0.5	-0.8	-0.5	-1.5
Emphysema/chronic bronchitis	0.4	0.4	1.3	0.7	0.3	0.6	0.5	-1.1	0.9	-0.1	-0.9	0.4	0.9	-0.3	-0.2	-0.5	0.7	-0.9	-0.7	-0.9	-0.4	0.7
Angina (self-reported)	0.4	0.5	1.3	1.0	1.1	0.8	0.5	0.6	1.1	-0.5	0.8	0.6	0.2	-0.4	0.9	-0.5	1.0	-0.6	-0.9	-0.7	0.1	0.7
Medication: Allopurinol	0.4	0.5	2.1	-0.6	-0.1	-0.2	-0.6	1.0	-0.3	-0.2	-0.5	-0.3	-0.1	0.5	1.0	0.6	0.1	1.4	0.8	1.4	0.0	1.2
Supplements: Vitamin C	0.4	0.5	4.4	0.6	-0.2	-0.4	-0.8	-1.5	0.2	0.3	-0.2	1.3	2.1	0.7	-0.1	0.3	0.2	-0.6	0.3	-0.2	0.1	-0.1
Knee pain experienced in last month	0.4	0.7	2.4	0.9	0.9	1.1	1.1	0.3	1.1	-0.5	0.1	-0.9	-0.6	-1.2	-0.2	-1.2	1.1	-0.5	-1.6	-0.1	0.5	0.1
Medication for cholesterol	0.4	0.7	2.6	1.2	1.6	0.5	-1.0	-0.7	0.7	0.6	0.5	1.1	-0.2	-0.2	0.3	-0.2	0.6	-1.0	-1.2	-1.4	0.5	-0.1
Medication: Aspirin	0.4	0.5	1.3	1.1	0.9	1.0	1.0	0.7	1.0	-0.6	0.4	-0.1	0.2	-0.8	-0.2	-1.1	0.2	-1.0	-0.9	0.4	-0.1	-0.8
Ever taken oral contraceptive pill	0.4	0.5	1.3	-0.4	-0.4	-1.0	-0.7	0.1	-1.1	-0.4	-0.3	0.2	0.9	0.8	-0.6	0.7	-1.1	0.7	1.1	1.0	0.1	0.2
Leg fat percentage (left)	0.4	1.6	4.7	-2.2	-1.8	-1.5	-0.4	-0.1	-1.5	-1.7	-1.1	-1.9	-1.7	0.2	-0.9	0.3	-2.0	0.4	1.1	1.2	-0.3	-0.8
Deep venous thrombosis (DVT) (self-reported)	0.4	0.5	1.5	-0.2	-0.5	-0.5	-0.7	0.3	-0.3	1.2	0.5	1.1	-0.6	0.8	0.7	1.0	0.3	0.5	0.0	-1.1	0.7	1.1
Depression (Nagel 2018)	0.3	0.4	1.3	-0.3	0.3	0.1	0.5	0.8	-0.1	-0.9	0.7	-0.4	-0.8	0.0	0.8	-0.1	0.1	0.9	0.8	1.2	-0.9	-0.1
Alzheimer’s Disease (in father)	0.3	0.3	2.1	-0.2	0.7	0.2	-0.1	-0.7	-0.0	0.3	-0.3	0.1	0.9	0.2	-0.1	0.7	0.1	1.0	0.1	-0.4	0.4	1.5
Crohns Disease (2017)	0.3	0.6	5.0	-0.0	0.2	0.1	1.3	0.7	-0.0	-2.2	-0.3	-0.8	0.0	-0.7	-0.1	-0.6	-0.2	-0.5	-0.3	0.4	-1.1	-1.0
Breast Cancer	0.3	0.7	4.7	-0.3	-0.3	-0.3	-0.3	1.5	-0.4	-0.2	-0.0	-1.1	-1.4	0.2	0.8	-0.0	-0.1	0.9	0.7	2.2	0.7	0.4
Neuroticism (2016)	0.3	0.4	2.5	0.0	-0.5	-0.8	-0.6	-1.2	-0.4	0.0	0.6	0.7	-1.6	0.7	-0.4	0.8	-0.1	0.1	0.4	-0.5	0.6	0.5
Heel T-Score	0.3	2.7	7.3	2.7	2.1	2.2	1.9	1.7	2.7	-0.6	0.8	-0.6	2.0	-1.9	0.7	-2.1	2.1	-1.1	-2.0	-0.2	-0.7	-0.3
Waist Hip Ratio (WHR)	0.3	1.4	6.8	1.4	0.5	0.3	0.6	1.4	0.8	-0.2	1.6	2.1	0.8	0.2	2.6	0.2	1.8	0.5	-0.5	-0.6	1.4	1.2
Smoking Status	0.3	0.7	3.0	1.7	0.1	1.1	1.1	0.2	1.1	-0.3	-0.0	1.0	0.1	0.0	0.1	-0.3	1.7	-0.5	-1.0	-0.8	0.7	0.9
Frequency of depressed mood in last 2 weeks	0.3	0.4	1.7	-0.6	0.0	-0.3	-0.2	0.1	-0.3	-0.8	-0.3	-0.1	-1.3	0.6	0.7	0.4	-0.5	0.6	1.0	0.5	-1.3	0.0
Systolic blood pressure, automated reading	0.3	0.9	4.0	-1.1	0.0	0.2	1.1	0.8	0.0	-0.8	-2.0	-1.9	1.3	-1.0	-0.5	-0.8	-0.6	0.3	0.3	1.4	-0.9	-0.4
Current tobacco smoking	0.3	0.4	1.3	0.8	-0.4	-0.2	0.3	0.6	0.1	0.6	0.9	0.9	-0.6	0.3	0.8	0.3	0.9	-0.3	-0.4	-1.2	1.1	0.1
Frequency of unenthusiasm / disinterest in last 2 weeks	0.3	0.3	1.1	0.7	0.8	0.7	0.7	0.4	0.7	-0.3	0.9	0.4	-0.4	-0.2	0.5	-0.5	0.5	-0.6	-0.4	-0.1	-1.0	-0.4
Heel bone mineral density (BMD) T-score, automated (left)	0.3	0.8	3.0	1.1	1.1	1.0	-0.1	0.5	1.1	-0.4	1.7	0.7	1.0	-0.6	1.1	-0.5	1.7	0.3	-0.6	0.1	0.5	0.7
Past tobacco smoking	0.3	0.6	2.2	-1.5	-0.2	-0.8	-0.8	-1.2	-0.9	1.1	0.1	-1.0	-0.8	-0.5	-0.2	0.3	-1.3	0.2	-0.3	-0.9	0.2	-1.0
Forced expiratory volume in 1-second (FEV1)	0.3	0.9	2.8	-1.4	-1.1	-1.1	-0.3	-1.3	-1.3	0.5	-0.5	-0.7	0.4	0.5	-1.7	0.5	-1.3	0.7	1.0	1.2	-0.4	-1.1
Happiness	0.3	0.4	2.1	0.5	-0.1	0.0	-0.5	-1.5	-0.3	-0.4	0.6	1.1	-0.3	0.2	0.9	0.3	0.8	0.2	-0.2	-0.7	0.4	-0.5
Impedance of arm (left)	0.3	1.2	4.3	1.2	1.0	0.2	-0.9	-1.0	0.3	-0.2	1.1	2.0	0.7	1.1	1.9	1.0	0.8	-0.5	-0.6	-2.1	1.4	0.6
Qualifications: O levels/GCSEs or equivalent	0.3	0.4	1.2	-0.4	-0.2	-0.6	-0.3	1.0	-0.8	-0.6	0.0	-0.0	-0.6	0.4	1.1	0.7	0.4	1.0	0.5	0.8	1.0	0.7
Blood clot in the leg (DVT)	0.3	0.4	1.9	-0.1	-0.4	-0.3	-0.5	0.2	-0.1	1.2	0.4	1.0	-0.7	0.6	0.4	0.8	0.3	0.3	-0.2	-1.4	0.7	1.1
Birth weight	0.3	0.7	2.8	0.7	0.7	1.0	0.7	-1.6	0.8	-1.0	-0.2	-0.3	-0.0	-0.5	-1.7	-0.6	-0.3	-0.9	-1.2	-0.8	-0.2	-0.7
Age at first live birth	0.3	0.6	2.5	1.6	0.6	0.1	0.1	0.5	0.4	-0.5	1.2	1.1	0.8	1.1	1.3	0.5	0.8	-0.3	0.3	0.0	0.5	0.4
Neck or shoulder pain in last month	0.3	0.5	1.7	-0.3	-0.8	-0.0	0.4	1.3	-0.3	-0.2	-1.2	-1.3	-0.6	-0.7	0.3	-0.8	-0.2	0.0	0.3	1.1	-1.0	-0.1
Medication: Ibuprofen	0.3	0.4	1.6	0.4	0.5	0.3	-0.6	1.3	-0.0	-0.5	0.1	-0.1	-0.7	0.3	1.2	0.2	0.5	0.7	0.4	1.1	0.2	0.5
Medication: Aspirin	0.3	0.4	0.9	0.9	0.7	0.9	0.9	0.7	0.8	-0.8	0.7	-0.1	-0.2	-0.4	-0.1	-0.8	0.1	-0.8	-0.6	0.8	-0.0	-0.8
Illnesses of father: Heart disease	0.3	0.4	1.7	0.1	0.8	0.5	-0.4	0.6	-0.1	-0.2	1.1	-0.2	1.2	-0.1	0.4	-0.2	0.4	0.6	0.3	1.3	0.4	-0.2
Average weekly red wine intake	0.3	0.4	2.3	0.1	-0.2	-0.6	-0.1	1.5	-0.3	0.1	-0.0	0.2	-0.1	0.7	-0.6	0.2	-1.3	-0.7	0.7	0.2	-0.9	-0.8
Long-standing illness, disability or infirmity	0.3	0.4	3.0	0.3	-0.3	-0.3	-0.9	-1.7	0.2	0.5	-0.1	0.8	0.5	0.5	0.6	0.4	0.7	-0.1	0.0	-0.8	0.0	1.0
Eye problems/disorders: Cataract	0.3	0.3	2.3	0.1	-0.3	-0.3	-1.1	-0.5	-0.2	0.7	0.7	0.4	0.4	0.4	0.3	0.5	0.1	0.1	-0.1	-0.1	1.5	0.7
Mouth/teeth dental problems: Mouth ulcers	0.3	0.4	1.5	-0.7	-0.1	0.0	-0.2	-0.9	-0.3	1.1	1.1	-0.0	1.1	-0.2	0.9	0.2	0.4	1.2	-0.1	0.4	0.4	0.7
Illnesses of father: None of the above (group 1)	0.3	0.4	2.8	0.2	-0.6	-0.8	-0.3	0.2	-0.1	-0.9	-1.7	0.0	-1.4	0.3	0.1	-0.1	-0.2	-1.0	0.3	0.2	-0.3	-0.0
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.3	0.7	2.0	-1.1	-1.2	-0.9	-0.4	0.2	-1.0	0.0	-1.3	-1.4	1.2	-0.2	-0.6	-0.2	-0.5	0.2	0.9	1.3	-0.9	-0.5
High cholesterol (Self-reported)	0.3	0.5	1.1	-0.7	-0.8	-1.0	0.3	1.0	-0.7	-0.7	0.2	-0.5	-0.0	0.8	0.5	0.4	-0.9	0.1	1.0	0.9	-0.4	-1.1
Fractured/broken bones in last 5 years	0.3	0.3	1.7	-1.2	-0.0	-0.4	-0.4	0.1	-0.7	0.1	-0.2	0.3	-0.3	0.1	0.8	0.7	-0.3	0.8	0.1	-0.7	0.7	1.3
Cholesterol lowering medication	0.3	0.4	1.2	-1.0	-1.1	-0.8	0.4	1.0	-0.4	0.1	-0.3	-0.8	0.4	0.6	0.3	0.4	-0.5	0.4	1.0	1.1	-0.7	0.3
Pain experienced in last month	0.3	0.5	2.1	0.6	0.3	-0.2	-0.9	-1.1	-0.1	0.1	0.7	1.4	1.3	1.0	0.2	0.8	0.0	-0.2	0.3	-0.8	0.8	-0.2
Alcohol drinker status: Previous	0.3	0.4	1.8	-0.3	-0.6	-0.4	-1.2	-1.4	-0.5	0.3	-0.5	-0.1	-1.2	-0.0	-0.5	0.1	-0.6	0.3	0.3	0.6	0.7	0.4
Irritable Bowel Disease (IBD)	0.2	0.5	2.0	0.3	0.6	0.8	1.4	0.3	0.5	-1.2	-0.4	-0.8	-0.1	-1.1	-0.1	-1.0	0.4	-0.5	-0.8	0.1	-0.9	-0.9
Ulcerative Colitis (UC)	0.2	0.4	1.1	0.6	1.1	1.0	0.9	0.4	0.8	-0.3	-0.1	-0.2	0.5	-0.8	0.4	-0.8	0.9	-0.1	-0.5	0.1	-0.5	-0.0
Ovarian Cancer	0.2	0.2	1.5	-0.6	0.1	0.1	0.6	1.2	-0.4	-0.1	0.1	-0.4	0.6	-0.6	-0.3	-0.1	0.0	0.8	-0.2	0.2	-0.2	-0.2
LDL Cholesterol	0.2	0.4	1.9	-0.1	-0.8	-0.5	0.6	1.0	-0.4	-0.7	-0.0	-1.2	-1.4	-0.2	-0.1	-0.2	-0.3	-0.1	0.1	0.7	0.4	-0.0
Height	0.2	3.7	11.9	-3.4	-3.5	-2.5	-1.7	-1.3	-2.8	0.8	-2.0	-1.6	-2.2	1.0	-1.6	1.5	-2.7	1.3	2.1	1.1	0.5	-0.6
Lung FVC	0.2	1.1	8.6	-0.5	-1.2	-0.6	0.1	-0.9	-0.8	2.9	0.5	0.4	1.9	0.1	-1.6	0.5	-0.5	0.4	0.1	-1.2	0.6	-0.7
Ever used hormone-replacement therapy (HRT)	0.2	0.3	1.0	-0.5	-0.6	0.1	-0.3	-0.4	-0.3	-1.0	-0.8	-0.3	0.8	-0.2	-0.2	0.1	-0.5	0.8	0.4	1.0	0.2	0.5
Vitamin and mineral supplements	0.2	0.2	1.7	0.0	-0.2	0.2	0.1	0.5	-0.0	-1.0	0.9	0.2	-1.3	-0.0	0.4	0.0	0.0	-0.0	0.1	-0.4	-0.0	-0.6
Serious illness, injury or assault to yourself	0.2	0.3	1.8	0.3	0.1	0.8	-0.1	-1.2	0.3	-0.2	-0.4	0.1	1.3	-0.5	0.1	-0.6	0.6	-0.4	-0.5	-0.0	0.3	-0.3
Multivitamins +/- minerals	0.2	0.3	1.7	-0.5	0.1	-0.0	0.1	0.7	0.1	-0.1	-0.7	-1.0	-1.3	-0.3	-0.5	-0.5	-0.0	-0.7	-0.2	0.3	-0.8	0.3
Nervous feelings	0.2	0.4	1.4	-0.9	-0.4	-0.7	-0.6	-0.5	-0.8	-0.0	-0.4	0.2	0.2	0.5	0.2	0.4	-0.9	0.5	1.2	1.0	-1.1	-0.6
Heart attack	0.2	0.3	1.2	-1.0	0.1	-0.2	0.2	0.9	-0.6	0.5	0.1	-0.8	0.2	0.1	-0.2	0.2	-1.1	0.5	0.8	0.8	-0.2	0.1
Impedance of arm (right)	0.2	0.8	3.0	1.0	1.1	0.2	-0.6	-0.5	0.4	-0.6	0.8	1.6	0.6	0.8	1.6	0.6	0.6	-0.6	-0.7	-1.7	0.7	0.1
Peak expiratory flow (PEF)	0.2	0.5	2.0	-0.7	-0.3	-0.5	0.3	0.3	-0.7	-0.9	1.1	-0.0	0.8	0.2	-0.7	0.2	-0.9	0.3	0.5	1.2	0.2	-1.4
Forced vital capacity (FVC), Best measure	0.2	0.8	3.6	-0.7	-1.3	-1.0	-0.4	0.2	-1.1	1.9	0.0	-0.2	0.8	1.0	-0.2	0.9	-0.5	1.3	1.3	1.2	0.2	0.3
Eye problems/disorders: None of the above	0.2	0.2	1.1	0.1	-0.8	-0.4	0.0	0.6	-0.4	1.1	0.1	0.3	0.1	0.8	0.2	0.6	-0.1	0.5	0.7	0.4	0.0	0.2
Pulse rate, automated reading	0.2	0.5	2.1	0.2	-0.8	0.2	1.2	1.4	0.6	0.4	1.1	0.1	0.3	0.3	0.8	0.1	1.1	0.7	-0.1	0.2	0.5	1.0
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.5	1.8	0.8	0.9	0.7	0.4	-0.6	1.0	0.5	0.7	0.7	-0.4	-0.5	1.1	-0.6	1.0	-0.4	-0.7	-0.5	-0.3	1.3
Handedness (chirality/laterality): Left-handed	0.2	0.2	0.9	-0.4	0.0	0.0	-0.5	1.0	0.0	-0.0	-0.1	-0.7	0.4	-0.1	0.8	0.0	0.6	0.6	0.2	0.7	-0.1	0.7
Smoking status: Current	0.2	0.3	1.5	0.8	-0.4	-0.1	0.3	-0.1	0.1	0.7	0.6	1.0	0.0	0.2	0.5	0.3	0.8	-0.2	-0.5	-1.2	1.1	0.2
Financial situation satisfaction	0.2	0.3	0.9	0.1	-0.9	-0.3	-0.2	-0.6	0.1	-0.4	0.8	0.6	0.1	0.1	0.7	-0.1	0.6	-0.6	0.1	-0.5	-1.0	-0.8
Eye problems/disorders: Glaucoma	0.2	0.3	1.3	-1.1	-0.1	0.1	0.9	0.6	-0.2	-0.7	0.2	-0.7	0.2	-0.8	-0.8	-0.5	-0.1	0.3	0.3	0.1	-0.6	-0.5
Pain type(s) experienced in last month: Hip pain	0.2	0.2	0.6	0.1	-0.6	-0.3	0.0	0.4	-0.2	0.1	-0.7	-0.5	-0.8	0.1	-0.0	0.1	-0.4	0.7	0.3	0.8	0.7	-0.0
Illnesses of father: High blood pressure	0.2	0.2	1.1	-0.6	0.4	0.4	0.6	0.5	0.1	0.5	0.6	-0.3	0.4	-0.6	-0.3	-0.2	-0.0	0.0	-0.6	-1.0	-0.4	0.2
Number of operations (self-reported)	0.2	0.2	1.5	0.1	-0.1	0.4	0.3	1.2	0.2	-0.9	0.1	-0.5	-0.0	-0.4	0.4	-0.4	0.1	0.6	0.2	0.9	0.3	0.1
Diastolic blood pressure, automated reading	0.2	0.6	3.4	-0.7	0.9	0.6	0.6	0.3	0.2	-0.8	-0.4	-1.2	1.1	-0.8	-0.1	-0.6	0.2	0.9	-0.1	1.8	0.2	0.7
Heart attack/myocardial infarction (self-reported)	0.2	0.2	0.9	-0.9	0.4	0.0	0.4	0.8	-0.3	0.3	0.1	-0.9	0.4	-0.2	-0.3	-0.0	-1.0	0.4	0.6	0.7	-0.3	0.1
Bipolar Disorder (2018)	0.1	0.2	0.6	0.5	0.7	-0.0	0.3	0.5	0.1	-0.7	0.3	0.6	-0.7	0.3	0.4	0.1	-0.4	0.1	0.4	0.2	0.3	-0.8
Blood Eosinophil Count	0.1	1.0	2.5	0.2	0.4	1.1	1.6	1.2	0.6	-1.6	0.3	-1.6	-0.3	-1.6	1.1	-1.4	1.1	0.3	-0.6	1.2	0.2	-0.5
Blood Platelet Count	0.1	0.8	2.9	-1.7	-1.0	-0.8	-0.2	-0.1	-1.0	-0.8	-1.0	-1.2	0.1	-0.5	-0.8	-0.2	-1.0	0.6	0.7	1.4	-0.7	-1.2
Tanning	0.1	1.2	7.1	0.0	-0.5	-0.3	-0.9	-2.1	0.5	2.4	-0.1	0.6	-1.6	0.2	-0.8	0.3	0.4	-1.2	-0.4	-2.7	-0.7	0.4
Other serious medical condition/disability diagnosed by doctor	0.1	0.2	0.7	0.2	0.3	-0.3	-0.5	0.5	-0.2	-0.5	-0.7	-0.6	-0.8	0.1	0.3	0.0	-0.3	0.1	0.1	0.7	0.7	-0.4
Supplements: Zinc	0.1	0.1	0.6	0.5	-0.5	-0.2	0.1	-0.2	0.2	-0.0	-0.5	-0.1	0.8	-0.1	-0.3	-0.3	0.4	-0.8	-0.2	-0.1	0.4	0.5
Sitting height	0.1	0.8	3.5	-1.4	-1.9	-1.3	-0.7	-0.9	-1.2	1.0	-0.5	-0.5	-1.4	0.4	-0.8	0.5	-1.1	-0.1	0.3	-0.0	0.2	-0.5
Forced vital capacity (FVC)	0.1	0.3	1.5	-0.5	-0.4	-0.2	0.2	-0.8	-0.5	0.9	-0.1	-0.2	1.2	0.1	-1.0	0.2	-0.2	0.9	0.4	1.0	0.0	-0.0
Qualifications: None of the above	0.1	0.3	2.1	0.2	-0.5	0.2	0.3	-1.0	0.4	1.4	-0.1	-0.3	0.5	0.0	-0.6	-0.1	0.3	-0.4	-0.3	-0.9	-0.2	-0.0
Mouth/teeth dental problems: Dentures	0.1	0.1	0.6	0.3	-0.2	-0.0	-0.0	-0.2	0.2	0.8	0.1	0.6	0.6	0.3	0.0	0.3	-0.5	0.2	0.1	-0.1	-0.1	-0.5
Had major operations	0.1	0.1	0.8	0.9	0.3	0.3	0.0	0.9	0.4	0.1	0.2	0.1	-0.4	0.3	0.2	-0.1	0.2	-0.1	0.0	0.3	0.6	-0.1
Qualifications: NVQ or HND or HNC or equivalent	0.1	0.1	0.7	0.7	-0.0	0.2	0.3	0.6	0.1	0.4	0.4	0.3	-0.2	0.8	0.4	0.4	-0.1	-0.1	0.1	-0.2	0.4	0.5
Hair Pigment	0.0	0.3	1.2	-0.2	0.3	0.2	0.2	-1.0	-0.3	-0.3	-1.0	-0.5	-0.0	-1.0	-0.4	-0.3	0.5	0.2	-0.8	-0.2	1.1	0.0

Hub : Genes

PANX1

Models

Trait associations