TWAS hub - PDE1B

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0880	0.0320	1.1e-03	0.002	0.027	0.017	0.027	0.011	1.5e-01	3.0e-04	2.8e-03	2.7e-04	1.3e-02
2	GTEx	Adipose Subcutaneous	0.1480	0.0480	1.2e-03	0.102	NA	0.109	NA	0.101	1.1e-08	NA	3.5e-09	NA	1.4e-08
3	GTEx	Artery Aorta	0.1480	0.0580	5.5e-03	0.146	NA	0.103	NA	0.112	2.0e-08	NA	2.7e-06	NA	9.9e-07
4	GTEx	Liver	0.4450	0.1200	1.5e-03	-0.006	NA	0.144	NA	0.082	4.9e-01	NA	8.2e-05	NA	2.7e-03
5	METSIM	Adipose	0.0458	0.0190	2.9e-03	0.050	0.004	0.030	0.025	0.039	5.5e-08	7.2e-02	2.0e-05	1.1e-04	1.5e-06
6	YFS	Blood	0.1412	0.0258	0.0e+00	0.085	0.090	0.116	0.119	0.123	2.9e-26	8.5e-28	5.9e-36	6.5e-37	3.8e-38
7	TCGA	Breast Invasive Carcinoma	0.0603	0.0190	1.4e-06	0.046	0.030	0.047	NA	0.043	7.5e-10	7.5e-07	5.7e-10	NA	2.7e-09
8	TCGA	Head and Neck Squamous Cell Carcinoma	0.0592	0.0309	9.6e-03	0.005	-0.001	0.001	NA	0.004	8.4e-02	4.9e-01	2.5e-01	NA	1.0e-01
9	TCGA	Ovarian Serous Cystadenocarcinoma	0.0670	0.0390	5.8e-03	-0.003	0.004	-0.003	NA	-0.004	6.3e-01	1.7e-01	6.7e-01	NA	9.3e-01

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Blood clot in the leg (DVT)	10.2	13.2	25.1	-3.4	-5.0	4.3	0.2	-4.6	3.4	-4.0	3.2	2.3
Deep venous thrombosis (DVT) (self-reported)	9.1	11.7	22.7	-3.1	-4.8	4.1	0.3	-4.2	3.2	-3.8	2.9	2.2
Friendships satisfaction	4.1	5.0	9.5	1.7	2.4	-2.5	1.0	2.2	-2.8	2.4	-3.1	-1.3
Noisy workplace	3.8	4.7	10.2	-1.1	-2.6	3.2	0.7	-2.5	2.9	-2.8	0.4	1.3
Alcohol drinker status: Previous	3.5	4.0	6.9	-2.6	-2.6	2.1	-0.9	-2.1	1.8	-1.9	1.2	2.0
Happiness	3.4	4.1	9.7	2.0	2.2	-1.8	1.7	1.9	-2.4	1.8	-3.1	-0.1
Taking other prescription medications	3.3	5.1	11.2	0.2	-2.5	2.6	-0.1	-2.6	2.2	-2.6	3.4	1.9
Number of self-reported non-cancer illnesses	3.2	5.5	8.9	-0.8	-3.0	2.7	-0.4	-3.0	1.9	-2.8	3.0	1.9
Mouth/teeth dental problems: Loose teeth	3.0	3.6	9.3	1.1	1.9	-2.5	-0.9	2.5	-3.1	2.1	-0.5	0.3
Had menopause	2.7	3.4	8.1	0.6	-1.5	1.6	1.4	-2.0	2.0	-2.1	2.8	1.8
Triglycerides	2.5	4.1	7.7	-1.3	-2.5	2.7	0.7	-2.2	1.5	-2.8	1.4	1.9
Exposure to tobacco smoke at home	2.4	2.7	6.2	0.6	-2.5	1.9	1.7	-1.4	1.7	-1.9	0.9	1.1
Medication: Bendroflumethiazide	2.4	3.7	6.9	1.8	1.6	-2.0	-2.6	2.1	-1.2	2.0	-2.2	-1.3
Frequency of depressed mood in last 2 weeks	2.3	3.2	6.0	-1.9	-2.1	2.1	0.1	-2.1	2.4	-2.1	1.1	0.8
Cholesterol lowering medication	2.3	3.3	5.7	0.4	-2.3	2.4	-0.7	-2.0	1.0	-2.1	2.0	2.1
High cholesterol (Self-reported)	2.2	3.8	6.4	1.7	-2.3	2.5	0.2	-2.2	1.3	-2.3	1.4	2.4
Alzheimer’s Disease (in father)	2.1	2.3	6.0	0.2	1.5	-1.7	-1.2	1.8	-2.5	1.8	-0.2	-1.4
Ever used hormone-replacement therapy (HRT)	2.1	2.7	4.0	1.9	-1.7	1.7	1.9	-1.3	1.5	-2.0	1.0	1.5
Number of incorrect matches in round	2.1	3.4	6.5	-1.7	-2.3	2.2	-0.6	-1.8	1.4	-2.2	2.5	1.1
Illnesses of siblings: Diabetes	2.1	2.5	4.5	0.5	2.0	-2.1	-0.5	2.0	-1.7	1.9	-1.2	-1.4
Nervous feelings	2.0	3.7	8.6	-2.9	-1.8	2.4	0.3	-1.9	2.0	-2.5	1.5	-0.1
Family relationship satisfaction	2.0	2.4	6.6	1.3	1.1	-1.5	1.0	1.8	-2.6	1.7	-1.1	-1.2
Depression (self-reported)	1.9	2.2	5.5	-2.3	-0.9	1.0	-2.4	-0.9	1.2	-1.3	1.4	1.2
Emphysema/chronic bronchitis	1.9	2.2	3.9	-1.0	-1.4	1.6	-0.0	-1.6	1.5	-1.7	1.6	2.0
Wears glasses or contact lenses	1.9	2.2	4.5	-0.7	-1.2	1.4	-0.5	-1.7	1.9	-1.5	2.1	1.6
Commuting to job workplace: Public transport	1.9	2.2	5.1	0.9	2.1	-1.7	0.0	1.1	-1.0	1.7	-2.3	-1.3
HDL Cholesterol	1.8	3.0	5.4	1.0	1.8	-2.1	1.4	1.9	-1.6	2.3	-1.4	-1.5
Medication: Blood pressure	1.8	3.1	9.9	1.5	1.4	-1.2	-3.1	1.6	-2.0	1.4	-2.0	0.5
Number of operations (self-reported)	1.8	2.6	5.4	0.3	-1.8	2.3	0.2	-1.8	2.1	-2.2	0.4	1.4
Blood Platelet Count	1.7	19.2	63.8	6.9	5.3	-3.0	-8.0	3.5	-1.1	2.7	-1.9	0.6
Hair/balding pattern: Pattern 2	1.7	2.2	7.2	2.7	0.9	-1.7	1.0	1.8	-0.7	1.4	-1.4	-0.7
Mouth/teeth dental problems: Bleeding gums	1.7	2.2	6.6	1.3	1.6	-1.4	1.8	0.9	-0.8	1.5	-2.6	-0.5
Mean time to correctly identify matches	1.7	3.2	14.0	1.1	-1.8	1.7	0.7	-1.5	1.0	-1.8	0.0	3.7
Eye problems/disorders: Cataract	1.7	2.0	6.2	0.1	1.8	-1.1	-2.5	1.3	-1.8	1.3	-0.1	-0.3
Average weekly champagne plus white wine intake	1.7	2.3	4.4	0.4	2.0	-2.1	-0.9	1.8	-1.5	2.0	-0.4	-1.2
Supplements: Calcium	1.7	1.8	3.4	0.8	-1.7	1.3	1.9	-1.7	1.4	-1.0	0.4	1.4
Financial difficulties in last 2 years	1.6	2.1	3.7	1.2	-1.8	1.8	0.6	-1.3	1.9	-1.7	1.6	0.5
Ever taken oral contraceptive pill	1.6	1.7	6.1	1.7	1.6	-1.4	0.7	0.9	0.0	1.1	-2.5	0.2
Systolic Blood Pressure	1.5	7.3	14.5	0.5	2.2	-2.5	-2.6	3.0	-3.8	2.6	-2.4	-3.3
Pulse wave reflection index	1.5	1.9	13.2	0.9	1.0	-0.6	3.6	0.6	-0.6	0.5	-0.9	-0.3
Medication: Omeprazole	1.5	1.8	5.0	-0.7	-0.7	1.5	-1.2	-1.0	1.2	-1.7	2.2	1.3
High blood pressure (mother)	1.4	2.0	7.3	-0.2	0.3	-1.2	-2.7	0.8	-1.2	0.9	0.1	-2.5
Medication: Lansoprazole	1.4	1.6	4.3	-2.1	-0.7	0.6	-0.9	-0.7	0.9	-1.0	2.0	-1.3
Reaction Time	1.3	2.4	12.1	0.8	-1.4	1.3	1.5	-1.2	0.6	-1.2	0.0	3.5
Mouth/teeth dental problems: Dentures	1.2	2.1	5.3	-1.2	-1.8	1.6	0.3	-1.2	0.9	-1.5	2.3	1.2
Length of working week for main job	1.2	1.4	5.3	-0.8	0.8	-0.9	-2.3	0.9	0.1	0.6	0.7	-1.8
Number of full brothers	1.2	1.5	3.4	0.8	-1.6	1.5	0.8	-1.7	1.8	-1.2	-0.3	0.3
Had major operations	1.2	1.4	2.8	-1.0	-1.4	1.2	-1.7	-1.1	1.2	-1.1	1.2	0.4
Leg pain on walking	1.2	1.5	2.9	0.6	1.3	-1.7	-0.0	1.5	-1.3	1.6	-1.4	-0.5
Pain type(s) experienced in last month: Hip pain	1.2	1.5	1.9	-1.1	-1.4	1.3	1.4	-1.0	0.9	-1.3	1.3	1.2
Pack years of smoking	1.2	1.7	7.1	0.4	-1.2	1.5	0.4	-1.1	0.9	-1.5	-0.3	2.7
Depression (Nagel 2018)	1.1	1.6	3.1	-1.1	-1.7	1.7	0.8	-1.1	1.2	-1.8	-0.1	0.7
Crohns Disease (2012)	1.1	1.7	6.7	-0.8	-1.4	0.6	2.6	-0.8	0.9	-0.7	1.9	0.6
HbA1C	1.1	1.2	3.7	-0.7	-0.6	1.1	1.2	-0.7	1.1	-1.4	1.9	-0.5
Pack years adult smoking proportion	1.1	1.6	7.7	0.9	-1.1	1.4	0.5	-0.9	0.4	-1.4	-0.3	2.8
Townsend deprivation index at recruitment	1.1	1.5	4.7	0.2	-1.6	1.7	0.5	-1.0	0.4	-1.2	0.6	2.2
Stomach or abdominal pain in last month	1.1	1.3	2.9	0.6	-1.5	1.3	1.7	-1.1	1.4	-1.0	0.7	-0.2
Hearing difficulty/problems with background noise	1.1	1.7	3.1	0.4	1.3	-1.8	1.0	1.6	-1.5	1.4	-0.4	-1.5
Worrier / anxious feelings	1.1	2.2	4.2	-0.8	-1.2	1.8	1.9	-2.0	2.0	-1.5	0.3	0.5
Breastfed as a baby	1.1	1.4	3.2	1.6	1.8	-1.5	-0.2	1.1	-0.8	1.2	-0.2	1.1
Qualifications: NVQ or HND or HNC or equivalent	1.1	1.3	4.2	-0.0	0.9	-1.3	-0.4	1.3	-0.9	1.1	-0.9	-2.1
Worry (Nagel 2018)	1.0	2.2	5.3	-1.4	-1.3	1.9	0.9	-1.8	2.3	-1.6	0.4	-0.2
Frequency of unenthusiasm / disinterest in last 2 weeks	1.0	1.3	2.9	-0.8	-1.6	1.6	0.5	-1.1	0.8	-1.7	-0.1	1.0
Supplements: Glucosamine	1.0	1.3	3.0	1.1	-1.7	1.5	1.1	-1.2	0.1	-1.3	0.8	0.4
Medication: Atenolol	1.0	1.3	3.1	0.4	1.0	-1.2	-0.8	1.4	-1.5	1.0	-0.1	-1.8
Medication: Simvastatin	1.0	1.5	4.0	0.7	-1.7	1.4	-0.2	-0.5	-0.1	-1.3	1.5	2.0
Hair/balding pattern: Pattern 3	1.0	1.5	2.8	-0.5	-1.2	1.4	0.6	-1.4	1.5	-1.4	1.7	0.4
Pulse rate	1.0	1.8	3.5	-1.9	-0.9	1.5	-1.2	-1.3	1.9	-1.4	0.7	-0.4
Illnesses of mother	1.0	1.2	3.2	-0.5	-0.7	1.3	1.1	-0.9	1.3	-1.1	-0.6	1.8
Medication for cholesterol, blood pressure or diabetes	1.0	1.6	8.5	-1.2	0.3	-0.4	2.9	-0.1	0.7	0.3	0.1	-2.0
Gout (self-reported)	1.0	1.3	2.7	-0.8	-1.1	1.2	-1.3	-1.5	1.6	-0.8	1.3	-0.3
Mood swings	1.0	1.8	4.2	-1.5	-1.1	1.4	-1.4	-0.9	2.1	-1.4	1.4	-0.0
Ever had prostate specific antigen (PSA) test	1.0	1.1	4.4	0.2	-1.1	0.9	-0.1	-1.1	1.1	-0.7	0.8	2.1
Crohns Disease (2017)	0.9	1.9	7.9	0.7	-1.2	0.6	2.8	-0.9	0.6	-0.7	2.1	1.0
Cardiovascular Disease	0.9	3.0	9.5	2.1	1.3	-1.4	-2.0	1.6	-3.1	1.2	-1.0	-0.8
Ever highly irritable/argumentative for 2 days	0.9	1.1	5.3	-1.1	0.8	-0.6	-1.0	0.3	-0.8	0.6	0.1	-2.3
Worry too long after embarrassment	0.9	1.5	4.0	-1.2	-0.3	0.9	1.8	-1.4	2.0	-0.8	-0.1	-0.9
Hypertension (Self-reported)	0.9	2.5	6.4	1.6	1.2	-1.0	-2.0	1.2	-2.0	0.9	-2.5	-0.8
Hearing aid user	0.9	1.0	3.5	-0.3	-0.9	1.0	1.0	-0.6	0.4	-0.9	1.9	0.9
Fractured/broken bones in last 5 years	0.9	1.2	2.8	-1.7	-1.4	0.7	0.8	-1.5	0.8	-1.1	0.8	0.2
Medication: Omeprazole (e.g. Zanprol)	0.9	1.1	3.2	-0.1	-0.6	1.2	-0.6	-0.9	0.5	-1.3	1.8	1.3
Bipolar Disorder (2018)	0.8	1.3	3.7	-1.9	-1.5	0.9	-0.9	-0.9	0.8	-1.3	0.9	-0.4
Irritable Bowel Disease (IBD)	0.8	1.9	7.1	-0.0	-1.2	1.0	1.9	-1.0	0.9	-1.2	2.7	0.9
Rheumatoid Arthritis	0.8	1.1	2.4	0.4	1.4	-1.5	1.1	1.1	-0.4	1.3	-0.8	0.7
Eye problems/disorders: Diabetes related eye disease	0.8	0.8	5.3	0.5	0.4	-0.5	-2.3	0.1	0.3	0.4	0.2	1.1
Severe depression (siblings)	0.8	0.9	3.1	-1.8	0.5	-0.8	-0.9	0.5	-1.3	0.8	-0.5	-0.9
Hand grip strength (right)	0.8	2.1	4.2	-1.1	1.1	-1.5	-1.1	1.7	-1.5	1.6	-2.0	-1.1
Tinnitus: Yes, but not now, but have in the past	0.8	0.9	2.5	-1.0	-1.0	0.7	-0.4	-0.8	1.6	-0.9	0.9	-0.6
High blood pressure	0.8	2.2	5.5	1.6	1.1	-0.9	-2.4	1.1	-1.7	0.7	-1.9	-1.1
Diverticular disease/diverticulitis (self-reported)	0.8	0.9	1.9	0.8	1.0	-1.2	0.6	0.9	-0.8	1.3	-1.4	-0.3
Hayfever/allergic rhinitis (self-reported)	0.8	1.1	3.4	-0.5	-1.3	0.7	-0.1	-1.2	0.9	-0.8	1.9	0.9
Neuroticism score	0.8	1.6	6.0	-1.2	-0.8	1.5	-0.4	-1.4	2.5	-1.3	0.0	-0.3
Reason for reducing amount of alcohol drunk: Health precaution	0.8	0.9	5.4	0.2	0.4	-0.4	-2.3	0.3	0.1	0.7	-0.0	-1.3
Eye problems/disorders: None of the above	0.8	0.9	2.9	1.1	0.2	-0.5	1.2	0.5	-0.3	0.6	-1.1	-1.7
Medication: Allopurinol	0.8	1.0	6.2	-0.4	0.4	-0.7	-2.5	0.7	-0.2	1.0	-0.1	-0.9
Medication: Aspirin	0.8	1.0	3.0	1.2	0.3	-0.9	-0.4	1.4	-1.7	1.1	0.3	0.6
Supplements: Vitamin C	0.8	0.9	1.8	0.2	1.0	-1.1	1.4	0.3	-1.1	1.1	-0.4	-1.2
Forced expiratory volume in 1-second (FEV1), predicted	0.8	1.6	5.0	-0.1	0.6	-1.0	1.7	1.0	-1.2	1.1	-1.2	-2.2
Medication for cholesterol	0.8	1.2	2.5	-0.9	1.4	-1.6	0.0	1.2	-1.1	1.5	0.0	-0.6
Medication: Aspirin	0.8	1.1	2.9	0.9	0.2	-0.8	-1.0	1.3	-1.7	1.0	0.7	0.9
Neuroticism (Nagel 2018)	0.7	1.6	4.6	-1.5	-1.0	1.5	0.6	-1.0	2.1	-1.1	-0.1	-1.2
Primary Biliary Cirrhosis	0.7	1.0	5.4	-2.3	0.3	-0.3	-1.4	0.5	-1.0	0.4	-0.0	-0.2
Sensitivity / hurt feelings	0.7	1.3	5.7	-2.4	0.1	0.4	-0.0	-0.6	1.3	-0.7	0.8	-1.5
Relative age of first facial hair	0.7	1.4	6.7	-1.4	-0.1	-0.3	-0.8	-0.2	0.2	0.2	2.6	-1.8
Other serious medical condition/disability diagnosed by doctor	0.7	1.0	2.4	-0.6	-1.1	1.4	0.1	-1.5	0.9	-1.0	0.8	0.6
Systolic blood pressure, automated reading	0.7	2.1	7.1	0.5	1.1	-1.2	-1.0	1.7	-2.7	1.1	-1.4	-1.4
Medication for hormone replacement therapy	0.7	0.8	1.5	1.0	1.2	-0.9	1.0	0.7	-0.1	0.9	-0.6	-1.1
Medication: Metformin	0.7	1.0	5.5	2.3	0.3	-0.3	0.0	0.2	0.6	0.2	-1.5	0.9
Hayfever, allergic rhinitis or eczema	0.7	1.6	3.8	0.9	0.6	-1.7	-0.7	1.1	-1.1	1.7	-0.7	-2.0
Qualifications: None of the above	0.7	1.6	8.2	0.6	-1.2	1.1	0.3	-0.8	0.8	-0.9	-0.8	2.9
Time employed in main current job	0.7	0.9	2.0	1.4	0.8	-1.0	-0.0	1.0	-1.2	1.1	0.2	0.6
Father’s age at death	0.7	0.9	1.4	-0.9	-1.2	1.1	-1.0	-1.1	0.3	-0.9	0.9	-1.0
Medication: Cholesterol lowering	0.7	1.2	3.6	1.0	-1.2	0.9	-1.0	-0.5	0.1	-0.9	1.2	1.9
Exposure to tobacco smoke outside home	0.7	0.9	1.4	1.2	-1.1	1.0	-0.1	-0.9	1.0	-1.1	-0.3	1.1
Commuting to job workplace: Car/motor vehicle	0.7	0.8	3.6	-0.4	-1.0	0.7	-0.3	-0.5	0.3	-1.2	1.9	0.6
Qualifications: nursing, teaching	0.7	1.0	2.3	0.6	1.3	-1.0	-1.5	0.7	-1.1	1.4	0.1	-0.2
Osteoporosis (self-reported)	0.7	0.9	3.5	-0.4	-0.5	0.5	1.9	-1.2	0.4	-0.5	1.2	0.6
Medication: Gliclazide	0.7	0.8	2.3	1.2	-0.6	0.7	1.5	-0.7	0.7	-0.5	0.6	0.9
Guilty feelings	0.7	1.0	2.0	-0.9	-1.4	1.2	-0.2	-1.1	1.3	-1.0	0.5	-0.6
Financial situation satisfaction	0.7	0.9	3.5	1.9	0.8	-0.9	0.4	1.3	-0.5	0.8	-0.7	-0.1
Medication: Blood pressure	0.7	1.3	3.9	-0.2	0.6	-0.8	-1.4	1.1	-0.6	0.5	-1.6	-2.0
Medication: Paracetamol	0.7	1.0	4.5	0.1	0.7	-0.8	-0.4	1.1	-2.1	1.1	-0.8	-0.7
Medication: Lisinopril	0.7	0.9	4.3	0.0	-0.8	0.6	-2.1	-0.6	0.4	-0.8	0.8	1.1
Commuting to job workplace: Cycle	0.7	0.9	3.6	-1.6	0.3	-0.6	-0.6	-0.2	0.8	0.1	0.4	-1.9
Vascular/heart problems diagnosed by doctor	0.7	2.0	4.6	-1.5	-1.0	1.0	2.1	-1.2	1.7	-0.8	1.9	0.8
Intelligence (Savage-Jansen 2018)	0.6	1.9	3.2	1.2	1.8	-1.6	-1.0	1.6	-1.8	1.4	-1.0	-0.8
Ulcerative Colitis (UC)	0.6	1.1	3.3	-0.8	-0.9	1.2	0.2	-0.8	0.7	-1.4	1.8	0.5
Body Mass Index (BMI) (2010)	0.6	0.8	3.6	-1.0	0.3	-0.5	-1.9	0.6	-0.9	0.2	0.9	0.9
Type 2 Diabetes (T2D) (2012)	0.6	0.7	4.0	2.0	0.2	-0.0	0.3	0.1	-0.2	-0.1	-0.4	1.3
BMI	0.6	3.5	8.8	-0.9	1.2	-2.3	-1.5	2.6	-3.0	1.9	0.3	-1.4
Neuroticism	0.6	1.4	5.1	-0.3	-0.7	1.2	1.2	-1.3	2.3	-1.1	0.5	-0.9
Ever had hysterectomy (womb removed)	0.6	0.7	2.0	0.7	-0.6	0.6	1.4	-0.2	0.8	-0.9	0.3	-1.2
Maternal smoking around birth	0.6	0.8	2.6	-0.9	-1.4	0.6	1.6	-0.8	0.1	-0.5	0.9	-0.3
Relative age voice broke	0.6	1.0	2.9	-1.5	-0.7	0.7	0.0	-1.2	0.7	-0.2	1.7	-0.9
Diabetes (self-reported)	0.6	1.0	7.6	0.5	-0.3	0.2	-2.8	-0.3	0.5	-0.2	-0.2	0.8
Medication: Ramipril	0.6	0.7	2.8	1.7	-0.8	0.8	0.7	-0.3	0.4	-0.7	0.0	1.1
Seen doctor (GP) for nerves, anxiety, tension or depression	0.6	0.9	1.8	-1.1	-0.7	0.5	-1.0	-1.0	0.6	-0.8	1.3	-1.1
Birth weight	0.6	1.3	6.9	-2.6	-0.9	0.8	0.9	-0.7	-0.3	-1.0	0.7	0.8
Number of children fathered	0.6	0.6	2.2	-0.3	-0.7	0.7	1.5	-1.0	0.8	-0.8	0.4	0.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.6	0.7	4.0	-0.5	0.1	0.5	0.7	-0.2	0.7	0.2	-2.0	0.7
Alcohol intake frequency.	0.6	1.4	3.7	-0.8	-1.9	1.3	-0.0	-1.1	1.0	-1.0	1.4	1.1
Smoking status: Previous	0.6	0.9	3.2	0.4	-0.1	-0.9	1.8	1.1	-1.1	0.8	0.3	-0.5
Long-standing illness, disability or infirmity	0.6	0.9	2.0	0.3	-1.2	1.0	-1.2	-0.8	0.6	-0.9	-0.0	1.4
Ever had stillbirth, spontaneous miscarriage or termination	0.6	0.7	2.7	0.3	-0.5	-0.1	1.6	0.4	-0.0	0.3	-1.5	-0.8
Mouth/teeth dental problems: Mouth ulcers	0.6	1.0	2.2	0.7	0.8	-0.9	1.5	0.9	0.2	0.8	-1.2	-1.5
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.6	0.7	2.3	0.0	-0.3	0.5	-1.5	-0.9	1.2	-0.6	0.1	1.1
Alzheimer’s Disease (including proxy)	0.5	0.7	2.2	-0.9	0.9	-0.7	-1.1	0.5	-1.5	0.6	0.5	-0.5
Major Depression (MDD)	0.5	0.6	1.8	0.5	0.6	-0.6	-1.0	0.8	-1.3	0.6	-0.7	0.1
Fasting Glucose	0.5	0.5	2.8	0.3	0.2	-0.2	0.3	0.7	-0.3	0.7	-0.8	1.7
Number of treatments/medications taken	0.5	0.8	1.4	0.7	-1.1	1.2	-0.9	-0.8	0.1	-0.9	0.9	1.1
Hearing difficulty/problems: Yes	0.5	0.8	5.5	-0.0	-0.6	0.2	2.3	-0.3	-0.7	-0.4	0.5	0.4
Angina	0.5	0.7	1.6	-1.0	-1.0	0.8	-1.0	0.1	-0.1	-0.8	1.3	-0.7
Average weekly fortified wine intake	0.5	0.6	3.5	0.1	-0.2	0.2	0.6	-0.6	1.0	0.0	-0.3	1.9
Qualifications: CSEs or equivalent	0.5	0.6	3.8	0.7	0.2	0.3	1.9	-0.1	0.8	0.0	-0.9	0.1
Multivitamins +/- minerals	0.5	0.6	1.9	-0.2	-1.4	0.9	0.8	-1.2	0.3	-0.5	-0.0	0.5
Alcohol usually taken with meals	0.5	0.9	1.9	-1.3	0.7	-0.7	-1.2	0.5	-0.6	0.4	1.4	-1.0
Heart attack	0.5	0.6	2.2	0.6	0.4	-0.3	1.5	0.4	-1.0	0.4	-0.7	1.0
Falls in the last year	0.5	0.7	4.5	-0.5	0.6	-0.4	-0.9	0.3	-0.6	0.1	-0.2	2.1
Qualifications: A levels/AS levels or equivalent	0.5	1.1	4.0	-1.2	0.9	-0.7	-1.1	0.5	-2.0	0.8	-0.8	0.3
Pulse wave Arterial Stiffness index	0.5	0.5	3.5	0.1	0.3	0.0	1.9	0.0	-0.1	-0.1	-0.9	-0.6
Tense / ‘highly strung’	0.5	0.8	4.1	-1.3	0.3	-0.1	-1.0	0.3	0.4	-0.0	-0.5	-2.0
Loud music exposure frequency	0.5	0.6	1.4	0.0	-0.9	1.0	1.2	-0.3	-0.1	-1.1	0.4	0.7
Qualifications: O levels/GCSEs or equivalent	0.5	0.8	2.5	0.8	1.0	-0.6	-1.5	0.5	-1.6	0.7	-0.2	-0.0
Health satisfaction	0.5	0.7	1.5	1.2	0.7	-1.0	0.9	1.0	-1.0	0.6	-0.0	-0.6
Neck or shoulder pain in last month	0.5	0.8	2.7	-0.4	-0.8	0.6	-1.6	-1.1	0.7	-0.6	0.2	0.9
Angina (self-reported)	0.5	0.6	1.2	-1.0	-1.0	0.9	-0.5	0.0	0.1	-0.9	1.1	-0.8
Number of full sisters	0.5	0.6	1.6	-0.5	0.8	-0.5	-0.1	0.9	0.2	0.7	-1.3	-1.1
Average weekly red wine intake	0.5	0.8	3.0	-0.0	1.7	-1.1	0.1	0.6	-0.5	1.0	-0.5	-1.1
Handedness (chirality/laterality): Left-handed	0.5	0.6	1.5	-1.0	1.2	-1.2	-0.1	0.9	-0.3	0.8	0.1	-0.1
Diabetes diagnosed by doctor	0.5	0.7	2.7	0.6	-0.6	0.7	-1.7	-0.7	0.9	-0.8	-0.0	0.9
Commuting to job workplace: Walk	0.5	0.5	1.5	-1.2	0.5	-0.4	0.9	0.2	-0.4	0.8	-0.6	-1.0
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.5	1.2	2.2	-1.0	-1.0	1.1	-1.5	-1.0	1.5	-1.0	0.7	0.3
Illnesses of father: High blood pressure	0.5	0.6	4.3	-0.0	-0.1	0.2	-2.1	0.3	-0.8	-0.1	-0.2	0.2
Diastolic blood pressure, automated reading	0.5	1.4	4.0	-0.5	1.1	-0.7	-0.6	0.8	-2.0	0.9	-1.5	-1.7
Unable to work because of sickness or disability	0.5	0.7	2.7	-1.0	0.5	-0.5	-1.6	0.4	-0.9	0.7	0.2	-0.8
Heart disease (siblings)	0.5	0.6	2.2	-0.5	-1.0	0.6	1.5	-0.5	0.8	-0.6	-0.1	0.1
Bipolar Disorder or Schizophrenia	0.4	1.0	3.1	-1.7	-0.7	0.1	-1.8	0.0	0.3	-0.2	0.0	-1.4
Schizophrenia vs Biploar Disorder	0.4	0.5	2.8	1.7	-0.1	0.1	0.9	0.0	0.2	0.0	0.0	0.9
Coronary Artery Disease (CAD)	0.4	0.4	1.3	-0.3	1.1	-1.0	-0.9	0.0	-0.4	0.0	0.0	-0.7
LDL Cholesterol	0.4	0.6	2.2	-0.3	-1.1	0.3	1.5	-0.8	0.8	-0.3	-0.5	0.6
Lupus	0.4	0.6	3.0	0.2	0.7	0.0	0.3	-0.2	-0.5	-0.0	-1.7	1.3
Neuroticism (2016)	0.4	0.5	2.3	-1.5	-0.2	0.2	-0.9	-0.0	0.2	-0.3	0.7	-1.0
Ulcerative Colitis	0.4	0.6	1.3	-0.9	-1.1	1.0	-0.7	0.0	0.9	-1.1	0.0	0.4
Waist Hip Ratio (WHR)	0.4	1.8	13.3	0.2	0.1	0.6	3.6	-1.3	0.9	-0.4	0.2	-0.3
Type 2 Diabetes (T2D) (2018)	0.4	0.7	3.0	-0.2	-0.4	0.3	-1.4	-0.6	0.5	-0.5	1.7	0.2
Lung FEV1/FVC ratio	0.4	2.0	6.0	-1.3	-1.7	0.8	-2.5	-1.1	-0.5	-1.0	2.0	0.4
Age when periods started (menarche)	0.4	1.1	2.5	-1.0	-0.8	1.4	-0.1	-1.4	0.7	-1.0	-0.2	1.6
Chronic bronchitis/emphysema (father)	0.4	0.5	2.7	-0.3	0.8	-0.5	-0.5	0.3	0.0	0.2	0.1	-1.6
Heel bone mineral density (BMD) T-score, automated (right)	0.4	1.0	2.3	0.1	1.2	-1.1	0.1	0.9	-0.9	1.1	-1.5	-0.9
Ever unenthusiastic/disinterested for a whole week	0.4	0.5	1.1	0.2	0.8	-0.8	0.7	0.7	-0.2	0.6	-0.9	-1.1
Mouth/teeth dental problems	0.4	0.6	2.9	-0.8	-0.4	0.2	-1.7	-0.3	0.0	-0.3	0.8	-1.0
Hip circumference	0.4	1.8	4.9	-1.1	0.9	-1.6	-0.5	2.0	-2.2	1.0	-0.3	-1.3
Alcohol intake versus 10 years previously	0.4	0.6	2.4	-0.3	-1.6	0.7	0.3	-0.8	1.0	-0.8	0.4	-0.1
Asthma	0.4	0.9	2.9	1.7	0.9	-0.8	0.4	0.7	-0.3	0.8	-1.2	0.7
Forced expiratory volume in 1-second (FEV1), Best measure	0.4	1.3	7.7	-0.7	0.6	-0.7	0.3	0.7	-0.7	0.9	-0.9	-2.8
Headache pain in last month	0.4	0.8	4.7	-0.5	-0.3	-0.5	2.2	0.2	0.1	0.5	-1.1	-0.4
Medication: Amlodipine	0.4	0.6	2.4	0.9	0.3	-0.4	-1.5	0.4	-0.1	0.4	-1.0	-0.7
Chronic bronchitis/emphysema (mother)	0.4	0.4	1.8	-0.0	-0.0	0.2	1.3	-0.1	0.1	-0.3	1.4	0.1
Seen a psychiatrist for nerves, anxiety, tension or depression	0.4	0.5	1.6	-1.3	0.4	-0.7	-0.5	0.2	-0.0	0.6	0.2	-1.2
Qualifications: College or University degree	0.4	1.1	2.6	-0.6	1.6	-1.0	-1.5	0.0	-1.0	0.9	0.1	-1.5
Migraine (self-reported)	0.4	0.5	2.0	-1.1	-0.2	0.1	1.4	0.2	-0.5	-0.4	-0.0	0.9
Suffer from ‘nerves’	0.4	0.7	2.9	-1.7	-0.6	0.7	0.4	-0.9	0.3	-1.0	0.3	-0.2
Age at last live birth	0.4	0.5	2.0	1.4	0.2	-0.5	0.1	0.4	-0.1	0.7	-0.8	-1.1
Back pain experienced in last month	0.4	0.6	2.5	-0.1	0.5	-0.8	0.2	0.5	-1.6	0.9	-0.9	-0.7
Breast cancer (self-reported)	0.4	0.5	1.9	0.3	-0.1	0.0	0.2	0.5	-1.0	-0.4	1.4	-0.9
Asthma (self-reported)	0.4	0.8	3.4	1.8	0.8	-0.8	0.4	0.6	-0.3	0.7	-1.0	0.8
Illnesses of father: None of the above (group 1)	0.4	0.6	2.0	-0.7	-0.6	0.5	1.4	-0.9	0.3	-0.2	0.3	-0.9
Arm fat mass (left)	0.4	1.6	4.6	-1.1	0.9	-1.5	0.2	1.8	-2.1	1.1	0.1	-1.1
Miserableness	0.4	0.7	1.8	-1.4	0.2	0.9	-0.3	-0.6	1.3	-0.5	-1.1	-0.2
Tinnitus: Yes, now most or all of the time	0.4	0.4	1.1	-1.1	-1.0	0.7	-0.1	-0.5	0.3	-0.7	0.2	-0.2
Supplements: Fish oil (including cod liver oil)	0.4	0.6	1.8	1.1	-1.3	1.1	0.3	-0.9	0.2	-0.2	0.2	0.2
Average weekly beer plus cider intake	0.4	0.5	2.1	-0.2	-0.8	0.7	-0.1	-0.4	0.7	-0.8	-1.5	0.1
Pain experienced in last month	0.4	0.7	1.3	-0.0	1.2	-1.0	-0.9	0.9	-0.6	1.0	0.6	-0.8
Heart attack/myocardial infarction (self-reported)	0.4	0.5	2.2	0.5	0.4	-0.2	1.5	0.4	-0.9	0.3	-0.6	0.9
Depressed Affect (Nagel 2018)	0.3	0.5	2.6	-0.9	-0.3	0.8	-0.6	-0.0	1.6	-0.5	-0.3	-0.3
Schizophrenia (2018)	0.3	0.7	2.4	-0.6	0.4	-0.7	-1.2	0.0	-0.5	1.1	0.0	-1.6
Alzheimer’s Disease (in mother)	0.3	0.4	1.6	0.3	1.2	-0.7	-0.1	0.4	-0.9	0.5	-0.0	0.3
Ovarian Cancer	0.3	0.5	1.9	-1.4	-0.2	0.3	-0.2	0.0	0.6	-0.1	0.5	-1.2
Schizophrenia (2014)	0.3	0.7	3.6	-0.7	0.2	-0.6	-1.4	0.0	-0.1	0.0	0.0	-1.9
Blood White Count	0.3	2.5	11.0	2.0	-0.8	0.7	-3.3	-0.4	0.7	-0.5	0.8	2.2
Smoking Status	0.3	0.7	1.6	0.6	0.8	-1.0	0.2	0.8	-0.6	0.9	-1.0	-1.3
Tanning	0.3	3.4	7.7	0.6	-2.0	2.1	2.8	-1.9	2.0	-2.1	1.4	-0.2
Hand grip strength (left)	0.3	0.7	2.4	-1.5	0.1	-0.7	-0.8	0.7	-0.2	0.7	-1.0	-0.8
Average weekly spirits intake	0.3	0.4	1.8	0.3	0.7	0.3	0.0	0.1	-0.7	-0.5	-0.1	1.4
Vitamin and mineral supplements	0.3	0.4	1.7	-0.0	0.7	-0.4	-1.3	0.8	0.2	-0.0	-0.4	0.1
Supplements: Zinc	0.3	0.3	1.3	0.1	-0.8	0.4	0.5	0.1	-0.3	-0.3	-0.3	-1.1
Diabetes (mother)	0.3	0.3	1.3	0.2	0.0	-0.3	-0.9	0.4	0.3	0.7	0.3	-1.1
Impedance of leg (right)	0.3	1.4	5.6	2.2	0.5	-0.1	2.4	-0.4	0.1	0.0	1.1	0.6
Trunk fat percentage	0.3	1.4	3.9	-0.5	0.8	-1.2	1.7	1.5	-2.0	0.9	0.3	-0.2
Current tobacco smoking	0.3	0.4	1.7	1.0	0.2	0.1	-0.5	-0.2	0.6	-0.3	-0.7	1.3
Fed-up feelings	0.3	0.5	2.2	-0.4	-0.5	0.7	-0.0	-0.6	1.5	-0.8	0.1	0.0
Bilateral oophorectomy (both ovaries removed)	0.3	0.3	0.6	-0.7	-0.4	0.5	0.5	-0.0	-0.2	-0.8	0.6	-0.7
Body mass index (BMI)	0.3	1.1	3.3	-0.4	0.5	-1.2	-0.7	1.7	-1.8	0.9	-0.1	-0.5
Impedance of leg (left)	0.3	1.4	7.0	2.2	0.6	-0.2	2.6	-0.3	0.1	0.1	0.8	0.1
Trunk fat mass	0.3	1.2	3.7	-1.0	0.6	-1.1	1.3	1.5	-1.9	0.7	0.3	-0.7
Had other major operations	0.3	0.4	2.8	1.7	0.5	-0.2	0.5	0.0	0.4	0.1	-0.2	0.5
Forced vital capacity (FVC)	0.3	1.1	6.8	-1.3	0.3	-0.1	1.0	0.4	-0.1	0.2	-0.0	-2.6
Fluid intelligence score	0.3	0.6	1.7	0.9	0.7	-0.2	-0.1	0.4	-1.3	0.5	-0.3	-1.3
Weight	0.3	1.5	3.2	-1.5	0.4	-1.2	0.1	1.7	-1.8	0.8	-0.1	-1.8
Forced expiratory volume in 1-second (FEV1)	0.3	1.1	6.9	-1.7	-0.0	-0.1	0.3	0.3	-0.3	0.2	0.1	-2.6
Serious illness, injury or assault of a close relative in last 2 years	0.3	0.4	2.0	0.4	-0.1	-0.4	-0.6	-0.2	0.6	0.5	-0.0	-1.4
Lung cancer (father)	0.3	0.4	1.1	-0.2	1.0	-0.6	-0.7	0.3	-0.3	0.8	-0.7	-0.5
Arm fat mass (right)	0.3	1.3	3.9	-1.1	0.6	-1.3	0.3	1.6	-2.0	0.9	0.2	-1.1
Hair/balding pattern: Pattern 4	0.3	0.8	2.6	0.2	1.3	-0.7	1.1	0.7	-0.5	0.4	-1.6	-0.4
Birth weight of first child	0.3	0.6	1.9	-1.2	-0.5	-0.5	-0.8	0.3	-0.2	0.3	1.4	-0.8
Peak expiratory flow (PEF)	0.3	0.7	4.0	-2.0	-0.7	0.3	0.1	-0.4	0.2	-0.4	0.1	-1.0
Medication: Ventolin 100micrograms inhaler	0.3	0.4	1.4	1.2	0.5	-0.1	0.1	-0.0	-0.3	0.1	-1.0	0.8
Forced vital capacity (FVC), Best measure	0.3	1.0	5.8	-0.8	0.6	-0.3	1.1	0.5	-0.4	0.5	-0.6	-2.4
Body fat percentage	0.3	1.1	3.4	-0.6	0.8	-1.2	1.3	1.4	-1.8	0.8	0.5	-0.2
Wheeze or whistling in the chest in last year	0.3	0.5	1.0	0.9	0.7	-0.7	0.1	0.8	-1.0	0.7	-0.3	0.6
Age at first live birth	0.3	0.5	0.9	0.5	0.9	-0.8	0.4	0.7	-0.7	0.9	-0.1	-0.7
Pulse wave peak to peak time	0.3	0.3	2.5	-0.0	-0.1	-0.2	-1.6	0.2	-0.1	0.3	0.6	0.2
Medication: Ibuprofen	0.3	0.4	1.4	0.5	-0.2	-0.2	1.2	0.1	0.2	0.6	-0.6	-0.9
Pulse rate, automated reading	0.3	0.8	2.2	-0.1	-1.0	1.5	0.2	-1.2	1.0	-1.1	0.8	-0.3
Comparative height size at age 10	0.3	1.4	2.9	-1.4	-1.7	1.5	0.7	-0.7	0.9	-1.6	0.8	0.6
Overall health rating	0.3	0.7	1.4	-0.3	-0.8	1.1	0.3	-0.9	1.0	-1.0	-1.2	0.4
Chest pain or discomfort	0.3	0.4	1.5	1.2	0.2	0.0	-1.1	0.3	-0.6	-0.1	-0.6	0.6
Knee pain experienced in last month	0.3	0.4	3.1	-0.2	0.2	-0.3	-0.5	0.5	0.3	0.1	-1.8	-0.3
Illnesses of father: Heart disease	0.3	0.4	1.2	0.0	0.5	-0.6	-0.8	1.1	-0.2	0.3	-0.5	0.6
Leg fat-free mass (right)	0.3	1.6	5.9	-2.4	-0.1	-0.5	0.0	1.0	-0.8	0.3	-1.2	-2.3
Arm fat percentage (left)	0.3	1.1	3.2	-0.8	0.9	-1.4	0.7	1.5	-1.8	1.0	0.3	-0.1
Loneliness, isolation	0.3	0.4	1.1	0.1	-0.5	0.6	-0.6	-0.4	0.7	-0.5	1.0	-0.6
Mineral and other dietary supplements	0.3	0.3	0.8	-0.9	0.9	-0.6	-0.3	0.5	0.7	-0.0	-0.6	-0.4
Leg predicted mass (right)	0.3	1.6	5.9	-2.4	-0.1	-0.5	0.0	1.1	-0.8	0.3	-1.2	-2.3
Medication: Atorvastatin	0.3	0.4	2.4	-0.6	0.0	0.4	-1.6	-0.6	0.2	-0.2	0.2	0.6
Myopia	0.3	0.4	2.0	0.5	0.2	-0.4	0.6	0.5	-1.4	0.6	0.2	-0.2
Verbal and Numeric Reasoning (VNR)	0.2	0.6	2.3	0.6	0.6	-0.6	-0.6	0.6	-1.5	0.7	-0.7	-0.4
Age at First Birth	0.2	0.3	1.2	0.5	-0.1	0.2	0.9	-0.2	1.1	-0.2	0.3	0.5
Height	0.2	3.4	10.0	-3.2	-1.6	1.6	1.8	-1.3	1.0	-1.9	1.4	-2.1
Hypothyroidism (self reported)	0.2	0.6	1.6	-1.1	0.4	-0.3	-1.3	0.3	-1.2	0.2	0.4	-0.4
Respiratory disease	0.2	0.5	1.4	1.0	0.8	-0.2	1.1	0.4	-0.3	-0.2	0.4	1.2
Lung FVC	0.2	0.8	3.0	0.8	-0.2	0.8	1.7	-0.1	1.0	-0.6	0.9	0.9
Leg fat-free mass (left)	0.2	1.3	4.6	-2.1	0.0	-0.5	-0.1	1.1	-0.9	0.4	-1.0	-1.9
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.5	0.9	0.0	0.7	-0.6	0.5	0.4	-0.9	0.7	-1.0	-0.6
Serious illness, injury or assault to yourself	0.2	0.3	1.2	-0.0	0.2	-0.3	-1.1	0.4	0.4	0.6	-0.5	0.4
Medication: Levothyroxine sodium	0.2	0.4	1.6	0.2	0.7	-0.5	-1.3	0.3	-0.8	0.4	-0.3	0.1
Sitting height	0.2	1.4	6.4	-1.8	-0.5	0.4	1.4	-0.5	0.3	-0.7	-0.0	-2.5
Leg predicted mass (left)	0.2	1.3	5.0	-2.2	-0.1	-0.4	-0.0	1.0	-0.8	0.3	-0.9	-1.9
Waist circumference	0.2	0.6	1.8	-0.9	0.2	-0.5	1.1	0.9	-1.4	0.2	-0.0	-0.3
Past tobacco smoking	0.2	0.3	1.1	-0.3	0.2	0.8	-1.0	-0.7	0.6	-0.5	-0.2	0.2
Frequency of tenseness / restlessness in last 2 weeks	0.2	0.3	0.9	-0.0	-0.5	0.4	-0.4	-0.4	0.3	-0.5	0.9	-0.7
Pain all over the body in last month	0.2	0.2	0.9	0.5	0.5	-0.0	-0.9	-0.1	-0.6	0.2	-0.2	0.2
Illnesses of siblings	0.2	0.3	0.5	0.3	-0.2	0.7	0.2	-0.7	0.6	-0.6	-0.1	0.7
Impedance of arm (right)	0.2	0.9	4.7	0.0	1.0	-0.6	2.2	-0.6	0.1	0.5	1.0	0.0
Arm fat percentage (right)	0.2	0.9	2.5	-1.1	0.7	-1.1	0.6	1.3	-1.6	0.8	0.4	-0.5
Trunk fat-free mass	0.2	1.0	4.2	-1.7	-0.6	0.0	-0.4	0.6	-0.6	-0.1	-0.8	-2.1
Frequency of tiredness / lethargy in last 2 weeks	0.2	0.3	1.8	0.2	0.0	0.1	1.3	0.2	-0.1	0.0	-0.7	0.2
Number of live births	0.2	0.3	1.4	0.3	0.4	-0.2	-0.9	-0.1	0.2	0.2	-0.5	-1.2
Medication: Ibuprofen (e.g. Nurofen)	0.2	0.3	1.7	0.2	-0.4	-0.1	1.3	-0.1	0.5	0.4	-0.2	-0.4
Prospective memory result	0.2	0.2	1.2	1.1	0.1	-0.2	0.8	0.4	-0.1	0.3	0.1	0.3
Impedance of arm (left)	0.2	1.1	5.3	0.6	1.4	-1.0	2.3	-0.1	-0.1	0.8	0.5	0.8
Trunk predicted mass	0.2	1.0	4.2	-1.8	-0.7	0.1	-0.5	0.6	-0.7	-0.1	-0.7	-2.0
Standing height	0.2	1.8	7.7	-2.3	-0.2	-0.2	1.7	0.1	-0.3	-0.1	0.0	-2.8
Medication: Paracetamol	0.2	0.4	1.1	0.1	0.5	-0.3	-0.3	0.6	-1.0	0.6	-1.0	-0.1
Glaucoma (self-reported)	0.2	0.2	0.7	-0.6	0.3	-0.2	-0.4	0.3	-0.2	0.4	-0.6	0.8
High blood pressure (siblings)	0.2	0.3	1.0	-0.5	0.2	-0.1	-1.0	0.0	0.6	0.1	0.5	-0.8
Leg fat percentage (right)	0.2	0.6	1.8	0.0	0.3	-0.6	0.8	1.0	-1.3	0.2	1.0	0.2
Arm fat-free mass (right)	0.2	0.9	2.5	-1.2	-0.4	-0.3	-0.2	1.3	-1.2	0.2	-1.0	-1.6
Comparative body size at age 10	0.2	0.4	1.7	1.3	0.4	-0.5	0.0	0.9	-0.5	0.6	-0.6	0.4
Shortness of breath walking on level ground	0.2	0.3	1.5	-0.2	0.7	-0.2	-0.3	0.0	0.4	-0.1	0.2	1.2
Medication for pain relief, constipation, heartburn	0.2	0.3	0.9	0.0	-0.2	0.4	0.3	-0.8	0.9	-0.7	-0.4	-0.8
Medication: Seretide 50 evohaler	0.2	0.3	0.9	1.0	-0.3	0.3	0.0	-0.5	0.3	-0.2	0.1	0.9
Whole body fat mass	0.2	1.0	3.1	-1.2	0.4	-0.9	0.8	1.4	-1.8	0.5	0.3	-0.8
Leg fat mass (right)	0.2	0.7	2.3	-0.8	0.3	-0.8	0.4	1.4	-1.5	0.5	0.4	-0.4
Arm predicted mass (right)	0.2	1.0	2.6	-1.2	-0.2	-0.5	-0.4	1.3	-1.2	0.3	-1.2	-1.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.2	0.2	0.5	-0.4	0.7	-0.4	-0.5	0.3	0.4	0.6	0.5	-0.1
Whole body fat-free mass	0.2	1.2	4.2	-2.0	-0.6	-0.1	-0.2	0.7	-0.7	-0.1	-0.9	-2.0
Ever had bowel cancer screening	0.2	0.3	0.5	0.7	-0.7	0.5	0.4	-0.2	0.3	-0.6	0.7	-0.4
Osteoarthritis (self-reported)	0.2	0.3	1.5	1.2	0.2	0.3	0.1	-0.0	-0.3	-0.2	0.6	-0.5
Smoking status: Current	0.2	0.4	1.0	0.7	0.3	0.1	-0.9	-0.2	0.6	-0.3	-0.8	1.0
Whole body water mass	0.2	1.3	4.9	-1.9	-0.4	-0.2	-0.3	0.9	-0.9	0.1	-0.9	-2.2
Mother’s age at death	0.2	0.2	0.9	0.1	-0.1	0.4	0.1	-0.6	0.4	-0.4	-0.0	1.0
Alcohol drinker status: Never	0.2	0.3	0.8	0.4	0.6	-0.5	-0.1	0.9	-0.2	0.6	-0.1	-0.5
Basal metabolic rate	0.2	1.2	4.5	-1.8	-0.2	-0.5	-0.1	1.1	-1.0	0.3	-0.8	-2.1
Leg fat percentage (left)	0.2	0.6	1.7	0.0	0.3	-0.8	0.9	1.2	-1.3	0.4	0.8	-0.3
Arm fat-free mass (left)	0.2	1.1	4.5	-1.6	-0.5	-0.2	-0.3	1.1	-1.1	-0.0	-0.8	-2.1
Irritability	0.2	0.3	0.8	-0.0	-0.4	0.5	-0.7	-0.4	0.9	-0.4	-0.7	-0.0
Age started oral contraceptive pill	0.2	0.3	0.6	0.6	0.7	-0.8	-0.0	0.6	-0.5	0.2	0.5	0.6
Ever depressed for a whole week	0.2	0.3	0.5	-0.4	0.6	-0.7	-0.5	0.4	-0.7	0.5	0.3	-0.1
Basal cell carcinoma (self-reported)	0.2	0.2	0.6	0.3	0.1	0.0	0.8	0.5	-0.6	-0.1	0.2	0.6
Impedance of whole body	0.2	1.2	6.6	1.1	1.0	-0.6	2.6	-0.4	-0.0	0.4	1.0	0.5
Leg fat mass (left)	0.2	0.8	2.4	-0.7	0.5	-1.0	0.5	1.5	-1.6	0.6	0.1	-0.7
Arm predicted mass (left)	0.2	1.0	4.5	-1.3	-0.5	-0.3	-0.3	1.1	-1.1	0.1	-0.5	-2.1
Mean Putamen Volume	0.1	0.1	0.4	0.2	0.5	-0.1	0.4	0.4	-0.6	-0.2	0.2	0.3
Blood Eosinophil Count	0.1	0.4	2.1	1.5	0.8	-0.4	-0.1	0.3	-0.2	-0.3	0.7	0.4
Blood Red Count	0.1	1.4	5.8	1.7	1.5	-0.4	-2.4	0.2	-0.9	0.2	-0.9	0.2
Heel T-Score	0.1	0.6	2.6	1.1	0.4	0.0	-0.4	0.0	1.1	-0.1	1.6	0.2
Allergy or Eczema	0.1	0.3	1.3	0.5	-0.9	0.2	-0.2	-0.6	0.4	-0.1	1.1	0.4
Chronotype (morning person)	0.1	0.2	0.8	-0.2	-0.9	0.5	0.6	-0.2	-0.4	-0.3	0.4	0.2
Medication: Co-codamol	0.1	0.1	0.3	0.5	0.2	0.3	0.6	-0.1	-0.1	-0.0	-0.2	-0.4
Diabetes (father)	0.1	0.2	0.5	0.4	0.3	-0.0	0.6	-0.2	0.1	0.1	-0.7	0.6
Allergy	0.1	0.1	0.5	-0.3	0.7	0.2	0.0	0.2	-0.1	-0.3	-0.7	0.1
Hypothyroidism/myxoedema (self-reported)	0.1	0.3	0.8	-0.6	0.1	0.3	-0.9	-0.3	-0.4	-0.4	0.9	0.2
Heart disease (mother)	0.1	0.1	0.7	-0.4	-0.8	0.1	-0.1	0.1	0.0	-0.0	0.5	0.1
Illness, injury, bereavement, stress in last 2 years	0.1	0.2	0.5	-0.7	0.2	0.2	0.4	-0.1	-0.4	-0.3	-0.5	-0.4
Eye problems/disorders: Glaucoma	0.1	0.1	0.3	-0.5	-0.4	0.2	0.5	-0.1	-0.5	-0.1	0.1	0.6
Ever smoked	0.1	0.2	1.2	0.4	-0.5	-0.3	1.1	0.0	0.6	-0.0	0.2	0.1
Risk taking	0.1	0.2	1.0	0.3	-0.2	0.3	-0.0	-0.2	1.0	-0.4	-0.3	0.3
Breast Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Prostate Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Bipolar Disorder (2011)	0.0	0.0	0.2	0.1	-0.5	0.0	0.1	0.0	0.0	0.0	0.0	0.2
Hair Pigment	0.0	1.0	2.2	-0.1	1.3	-1.1	0.2	1.0	-1.5	1.5	-0.7	-0.4

Hub : Genes

PDE1B

Models

Trait associations