Hub : Genes

PDGFRL

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.1400 0.0430 1.8e-04 0.062 0.026 0.108 0.093 0.093 4.8e-08 0.00036 4.1e-13 2.0e-11 2.1e-11
2 GTEx Brain Cerebellum 0.4480 0.1170 1.8e-03 -0.004 NA -0.004 NA -0.004 4.3e-01 NA 4.4e-01 NA 4.2e-01
3 GTEx Cells Transformed fibroblasts 0.3810 0.0940 1.4e-04 0.000 NA -0.002 NA 0.008 3.0e-01 NA 5.1e-01 NA 7.6e-02
4 GTEx Esophagus Mucosa 0.4480 0.0980 1.3e-03 0.006 NA -0.001 NA 0.003 1.2e-01 NA 3.9e-01 NA 1.9e-01
5 GTEx Heart Left Ventricle 0.1501 0.0492 1.1e-03 0.051 NA 0.072 NA 0.056 1.1e-03 NA 1.1e-04 NA 5.9e-04
6 GTEx Muscle Skeletal 0.0869 0.0348 7.9e-03 -0.003 NA 0.006 NA -0.003 9.3e-01 NA 7.4e-02 NA 9.0e-01
7 ROSMAP Brain Pre-frontal Cortex 0.1916 0.0472 4.3e-06 0.070 0.028 0.036 0.068 0.056 2.7e-09 0.00012 1.7e-05 3.9e-09 8.4e-08
8 TCGA Head and Neck Squamous Cell Carcinoma 0.0817 0.0323 9.9e-04 0.032 0.026 0.028 NA 0.027 1.6e-04 0.00058 3.5e-04 NA 4.9e-04

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bipolar Disorder (2018) 0.7 1.1 4.2 1.6 0.4 0.2 0.3 2.1 0.7 0.8 -0.3
Bipolar Disorder or Schizophrenia 1.1 2.7 7.5 2.7 -0.4 0.3 1.1 2.6 0.2 1.7 -1.7
Depressed Affect (Nagel 2018) 0.2 0.4 1.2 -0.4 0.5 -0.7 -0.8 0.0 -0.0 -0.3 1.1
Depression (Nagel 2018) 0.7 1.0 3.2 1.8 0.1 -0.1 0.4 -0.7 -0.9 1.6 -1.0
Intelligence (Savage-Jansen 2018) 0.4 1.3 4.0 1.2 1.0 -0.9 0.5 -0.6 -2.0 1.0 -1.3
Neuroticism (Nagel 2018) 0.5 1.1 4.9 -0.6 0.0 -1.1 -1.2 0.0 0.4 -1.0 2.2
Schizophrenia (2018) 0.9 1.9 4.7 2.2 -0.8 0.1 1.0 1.7 -0.4 1.5 -1.9
Schizophrenia vs Biploar Disorder 1.1 1.5 7.1 1.1 -0.7 0.1 -1.0 -0.1 -0.7 1.3 -2.7
Worry (Nagel 2018) 1.0 2.2 6.8 -1.1 -0.4 0.0 -1.6 1.3 0.2 -2.2 2.6
Alzheimer’s Disease (in mother) 0.2 0.2 0.7 -0.1 0.4 0.1 0.8 0.4 0.3 -0.7 0.4
Alzheimer’s Disease (in father) 0.8 0.9 2.6 0.8 -0.3 -1.5 -1.6 -0.0 1.2 0.2 -0.3
Alzheimer’s Disease (including proxy) 0.1 0.2 0.4 0.4 0.3 -0.5 0.1 -0.0 0.6 -0.6 0.6
Crohns Disease (2017) 0.6 1.3 2.8 1.7 0.6 1.2 -0.2 1.7 1.1 1.2 -0.6
Irritable Bowel Disease (IBD) 0.2 0.5 1.3 0.6 1.1 1.2 1.0 0.1 0.1 0.2 0.1
Ulcerative Colitis (UC) 0.6 1.1 3.3 -0.5 1.1 0.5 1.8 -1.2 -0.8 -0.7 1.0
Major Depression (MDD) 0.7 0.8 3.4 1.1 0.0 0.2 0.6 1.8 -0.7 0.9 -0.7
Reaction Time 0.6 1.1 2.9 0.9 0.9 0.2 1.7 1.4 0.1 0.6 -1.3
Verbal and Numeric Reasoning (VNR) 0.1 0.3 1.1 0.9 -0.1 -0.2 0.2 0.1 -1.1 0.5 -0.4
Breast Cancer 0.6 1.5 5.6 -0.3 1.1 2.4 1.1 -1.6 -0.1 -1.2 0.1
Ovarian Cancer 2.0 2.7 14.1 1.6 -3.8 0.5 -0.6 0.3 0.5 2.0 0.1
Prostate Cancer 0.8 1.1 2.9 0.6 -1.2 -1.7 -1.2 -0.1 1.3 0.5 -0.9
Age at First Birth 0.4 0.6 1.9 -0.5 0.6 -1.2 1.4 -0.4 -0.2 -0.5 0.9
Bipolar Disorder (2011) 1.0 1.0 4.4 1.3 0.7 -0.1 0.2 2.1 -0.1 0.7 -0.8
Body Mass Index (BMI) (2010) 1.3 1.8 5.4 -1.5 -0.8 1.0 -1.6 -2.3 -1.7 -0.5 0.3
Coronary Artery Disease (CAD) 0.6 0.7 2.0 0.3 -0.8 0.6 -0.3 1.3 0.6 0.4 -1.4
Crohns Disease (2012) 0.4 0.7 1.7 1.3 1.2 -0.0 0.3 1.1 0.1 0.9 -0.7
Mean Putamen Volume 1.1 1.2 5.6 -0.0 2.4 0.2 -1.3 -1.1 -0.9 0.1 -0.6
Fasting Glucose 1.6 2.0 8.6 -0.3 0.3 2.9 1.4 -0.5 2.1 0.6 0.1
HbA1C 0.6 0.7 2.1 0.2 -0.3 1.4 -1.5 -0.1 -0.3 -0.4 1.1
HDL Cholesterol 0.5 0.9 3.5 0.0 -1.9 -1.0 -0.9 0.2 1.2 0.4 0.0
LDL Cholesterol 0.4 0.7 2.3 -0.5 -0.5 -0.1 0.0 -1.1 -0.7 -0.9 1.5
Lupus 0.6 0.9 2.7 -1.3 0.2 0.2 1.0 0.0 0.3 -1.6 1.4
Neuroticism (2016) 0.3 0.5 2.5 0.1 1.6 0.0 -0.4 0.5 -0.8 0.3 0.5
Primary Biliary Cirrhosis 0.6 0.9 2.0 0.7 -1.4 1.1 0.9 -0.2 -1.0 0.9 -0.8
Rheumatoid Arthritis 0.9 1.2 3.0 -0.7 1.4 0.7 -0.9 1.1 1.7 -0.9 0.6
Schizophrenia (2014) 1.2 2.5 6.4 2.5 -0.3 1.0 0.6 2.2 -0.4 1.8 -2.1
Triglycerides 0.9 1.5 3.7 -1.4 -1.0 1.2 0.1 -0.7 -0.8 -1.9 1.7
Type 2 Diabetes (T2D) (2012) 1.3 1.5 4.2 1.1 0.4 1.6 -0.5 1.3 1.2 2.0 -0.9
Ulcerative Colitis 0.7 1.0 4.4 0.3 1.5 0.1 2.1 -0.8 -0.2 -0.2 0.3
Blood Eosinophil Count 0.1 0.8 2.8 0.5 0.2 0.5 0.2 0.5 -1.1 1.1 -1.7
Blood Platelet Count 0.0 0.4 1.4 -1.2 -0.5 -0.2 0.4 -0.2 0.2 -0.9 0.4
Blood Red Count 0.1 1.0 2.8 -1.6 -0.5 -1.7 0.8 0.6 0.9 -0.7 0.6
Blood White Count 0.1 0.6 2.1 -1.0 0.2 1.4 0.6 1.0 -0.3 0.0 -0.7
Heel T-Score 0.1 0.9 2.9 1.6 0.1 0.9 -0.9 1.7 -0.0 0.2 -0.4
BMI 0.2 1.0 3.9 -0.3 -1.3 0.4 -1.0 -2.0 -1.2 -0.1 -0.2
Height 0.2 3.4 17.0 -0.1 2.2 -1.4 -1.0 -4.1 0.5 1.2 0.8
Waist Hip Ratio (WHR) 0.5 2.4 5.7 -1.3 1.3 1.2 -1.7 -2.0 -2.4 -1.2 -0.6
Systolic Blood Pressure 0.2 1.0 1.6 1.2 -1.2 0.7 -1.1 -0.9 -1.2 0.1 0.9
Smoking Status 0.3 0.7 2.5 -1.1 -0.6 1.6 -0.2 -0.2 0.8 -0.7 -0.1
Allergy or Eczema 0.3 0.9 6.4 0.5 2.5 0.5 0.1 -0.1 0.3 0.2 0.3
Cardiovascular Disease 1.1 3.6 12.3 -0.0 -1.6 1.3 -3.5 -1.1 -1.3 -1.5 2.7
Hypothyroidism (self reported) 0.5 1.1 5.2 0.3 0.9 0.0 -2.3 -0.7 -0.9 -0.2 -1.1
Respiratory disease 0.7 1.7 4.0 -1.1 1.1 1.1 -1.8 -2.0 -1.1 -1.0 0.1
Type 2 Diabetes (T2D) (2018) 0.6 1.1 2.6 -0.3 -1.2 1.1 -1.6 -0.7 -0.9 -0.5 -1.3
Lung FEV1/FVC ratio 1.9 9.8 40.3 -0.4 0.9 4.3 0.7 6.3 4.1 0.8 0.3
Lung FVC 0.2 1.0 2.1 -1.2 -1.1 -0.7 0.7 0.2 0.6 -1.5 1.4
Neuroticism 0.2 0.5 1.4 -0.2 0.3 -0.7 -0.7 0.3 -1.2 -0.8 0.9
Chronotype (morning person) 0.4 0.8 4.6 -0.9 -0.6 -2.2 0.1 0.6 0.3 -0.2 -0.5
Hair Pigment 0.1 1.6 5.2 1.0 -2.0 0.9 0.7 -0.6 -2.3 0.9 -0.6
Tanning 0.1 0.6 2.2 0.2 1.5 -0.7 -0.7 1.0 0.7 -0.1 -0.5
Hand grip strength (left) 0.3 0.9 2.8 -1.0 1.2 1.7 -0.6 -0.2 0.9 0.9 -0.1
Number of treatments/medications taken 0.9 1.7 4.9 0.6 1.1 1.2 -2.2 -0.3 1.6 -1.1 1.2
Average weekly spirits intake 0.5 0.6 1.9 1.4 0.4 1.2 0.1 -0.3 0.0 1.1 -0.1
Sensitivity / hurt feelings 0.4 0.7 1.5 0.2 -0.5 -0.7 0.9 -1.1 0.6 -0.9 1.2
Frequency of depressed mood in last 2 weeks 0.3 0.4 2.2 0.4 0.3 -0.5 0.6 -0.7 -1.5 -0.1 0.2
Hearing difficulty/problems: Yes 0.5 0.8 4.0 0.8 -2.0 -0.6 0.9 -0.1 -0.8 0.3 -0.1
Relative age of first facial hair 0.4 0.9 2.5 0.2 0.1 1.5 1.6 0.3 -0.8 0.2 -1.2
Other serious medical condition/disability diagnosed by doctor 0.6 0.8 3.1 0.3 1.8 0.2 -1.0 -0.6 -0.9 -0.8 0.1
Ever used hormone-replacement therapy (HRT) 1.2 1.6 7.3 0.3 2.7 0.2 0.8 1.9 0.1 0.6 -0.7
Ever had hysterectomy (womb removed) 1.6 1.8 4.8 0.6 1.8 0.5 -0.7 1.7 2.2 1.2 0.7
Systolic blood pressure, automated reading 0.4 1.2 1.9 1.3 -0.2 1.2 -0.4 -1.2 -1.4 1.3 -0.8
Eye problems/disorders: Diabetes related eye disease 0.8 0.9 3.3 0.6 1.8 -0.0 -0.8 0.3 0.9 1.0 -1.0
Angina 0.6 0.7 3.8 0.5 0.6 0.3 -0.6 -1.9 -0.9 0.4 -0.4
Medication for hormone replacement therapy 1.0 1.1 6.7 0.2 0.6 -0.0 -1.1 2.6 -0.4 -0.2 -0.6
Vitamin and mineral supplements 0.8 1.1 4.6 -1.7 -0.5 0.3 -0.4 -0.5 -2.1 -0.7 -0.5
Supplements: Zinc 1.0 1.1 4.1 0.3 1.4 -2.0 -1.4 -0.1 -0.4 0.2 0.4
Medication: Co-codamol 1.2 1.3 2.7 0.0 -1.5 0.8 1.1 -1.6 -1.6 0.3 -1.2
Medication: Metformin 0.9 1.2 4.0 1.2 0.8 1.1 -1.0 -0.8 -0.9 0.3 -2.0
Diabetes (father) 0.4 0.5 1.6 -0.5 0.9 1.3 0.2 0.8 0.5 -0.0 0.3
Diabetes (mother) 0.6 0.8 2.2 0.6 1.5 -0.0 -1.0 -0.4 -0.7 0.6 -1.4
Severe depression (siblings) 1.4 1.5 3.5 1.9 0.6 -0.9 1.6 0.1 0.2 1.7 -1.4
Pack years adult smoking proportion 0.8 1.2 2.6 -1.5 1.1 0.7 -0.2 -0.6 1.2 -1.6 1.2
Impedance of leg (right) 0.2 1.0 3.6 0.8 -1.6 -0.0 -0.8 1.9 0.5 -0.3 -0.7
Leg fat-free mass (left) 0.2 1.1 6.5 -0.9 0.7 -0.5 -0.0 -2.5 -0.8 0.7 0.1
Trunk fat percentage 0.5 2.1 6.9 -0.4 -2.3 0.6 -0.0 -2.6 -1.5 -0.1 -1.4
Hand grip strength (right) 0.2 0.6 1.3 -0.9 0.7 1.1 -0.4 -0.8 1.1 0.7 -0.3
Townsend deprivation index at recruitment 1.3 1.9 7.9 -0.3 -0.2 2.8 -1.7 -1.1 0.0 -1.1 1.4
Current tobacco smoking 0.3 0.5 2.3 -0.8 0.2 0.2 -0.5 0.8 0.7 -1.5 0.2
Average weekly fortified wine intake 1.0 1.2 2.6 -1.1 -0.9 0.9 1.1 -1.0 -0.5 -1.6 1.4
Maternal smoking around birth 0.3 0.5 1.6 0.1 0.5 1.3 -0.1 0.8 -1.1 -0.2 0.3
Fed-up feelings 1.2 2.1 5.2 -1.7 1.1 -1.7 0.9 -0.9 0.2 -2.3 1.8
Frequency of unenthusiasm / disinterest in last 2 weeks 0.3 0.5 2.5 1.6 -0.0 -0.3 -0.0 -0.5 -0.4 0.9 -0.1
Relative age voice broke 0.7 1.0 2.5 -1.5 -0.2 1.0 -0.0 -1.2 0.1 -1.6 1.0
Taking other prescription medications 0.9 1.4 3.1 0.0 1.7 1.6 -1.8 -0.9 0.5 -0.8 0.6
Age when periods started (menarche) 0.9 2.2 5.3 -2.3 -0.0 0.5 -1.1 0.6 1.7 -1.9 2.0
Bilateral oophorectomy (both ovaries removed) 0.8 0.9 2.5 1.4 0.5 -0.6 -1.0 0.7 0.7 1.6 -0.7
Heel bone mineral density (BMD) T-score, automated (left) 0.2 0.5 1.3 1.1 -0.5 -0.1 0.0 1.0 0.9 0.8 -0.3
Tinnitus: Yes, but not now, but have in the past 1.4 1.5 5.8 -0.1 -1.0 -0.4 0.6 2.4 2.1 0.3 -0.3
Qualifications: CSEs or equivalent 1.3 1.8 5.7 -0.7 0.8 0.6 0.2 1.0 1.4 -2.0 2.4
Serious illness, injury or assault to yourself 0.7 0.8 2.1 1.4 1.4 1.0 0.2 -0.8 -0.3 0.8 0.0
High blood pressure 0.9 2.6 7.8 1.2 -1.5 1.4 -2.8 -0.7 -2.1 -0.5 1.4
Hayfever, allergic rhinitis or eczema 0.5 1.2 6.0 -0.1 2.4 0.0 -0.6 0.4 1.2 -0.3 1.2
Multivitamins +/- minerals 0.6 0.7 2.8 1.7 0.2 -0.1 -0.5 0.4 0.9 1.2 -0.4
Stomach or abdominal pain in last month 0.2 0.3 0.8 0.4 -0.9 0.5 0.1 -0.2 -0.9 0.3 -0.2
Supplements: Glucosamine 0.3 0.4 1.6 0.7 -0.3 -0.6 1.3 -0.3 0.0 0.6 -0.1
Diverticular disease/diverticulitis (self-reported) 0.6 0.7 2.0 1.1 0.5 -0.6 0.2 -1.0 -1.4 0.4 -0.8
Medication: Atenolol 0.4 0.5 1.5 0.0 -0.1 -0.5 -0.4 -1.2 -0.4 -0.8 1.2
Medication: Levothyroxine sodium 0.7 1.2 6.7 0.8 1.0 0.1 -2.6 -0.7 -0.5 0.4 -0.7
Sitting height 0.1 0.7 1.8 0.9 -0.0 -0.2 -0.9 -0.6 1.4 1.0 1.0
Chronic bronchitis/emphysema (father) 0.4 0.5 1.0 0.7 -0.1 -0.5 -0.5 -0.8 -1.0 0.9 -0.7
High blood pressure (mother) 0.8 1.1 3.1 0.8 0.1 1.5 -0.8 -1.8 -1.5 -0.1 0.2
Body mass index (BMI) 0.2 1.0 5.0 -0.8 -0.6 0.5 0.6 -2.2 -0.9 0.3 -0.9
Impedance of leg (left) 0.2 0.9 2.5 1.2 -1.3 0.7 -0.7 1.6 0.6 -0.3 -0.6
Leg predicted mass (left) 0.2 1.1 6.5 -0.9 0.7 -0.5 0.0 -2.5 -0.8 0.7 0.2
Trunk fat mass 0.4 1.9 8.4 -0.4 -1.6 0.3 -0.1 -2.9 -1.5 0.2 -1.2
Waist circumference 0.7 2.5 10.0 -0.5 0.4 1.1 -0.4 -3.2 -2.2 0.7 -1.8
Number of incorrect matches in round 0.4 0.6 2.5 0.3 0.9 1.6 -0.2 -0.7 0.7 0.3 -0.6
Past tobacco smoking 0.3 0.5 1.8 0.6 0.7 -1.0 0.4 1.3 -0.1 0.5 0.5
Alcohol usually taken with meals 1.0 1.6 3.4 1.6 0.3 -1.8 0.4 1.8 1.4 0.4 1.0
Nervous feelings 0.7 1.3 4.2 -0.4 0.9 0.0 -0.7 1.9 0.2 -1.3 2.0
Frequency of tenseness / restlessness in last 2 weeks 0.5 0.8 3.0 0.4 0.7 -0.3 1.1 -1.1 -1.7 -0.8 -0.1
Hearing difficulty/problems with background noise 0.5 0.8 3.8 0.2 -0.3 -2.0 0.8 0.3 0.4 -0.1 1.4
Hair/balding pattern: Pattern 2 0.5 0.7 2.8 -0.3 0.2 -1.7 0.4 -1.4 -0.5 0.0 0.2
Had menopause 0.8 1.0 3.7 0.9 0.2 -0.1 1.9 -0.7 0.2 1.3 -1.1
Had other major operations 0.5 0.7 2.8 0.3 -0.7 0.7 1.0 -1.7 -0.1 -0.2 0.6
Forced vital capacity (FVC) 0.2 0.7 1.5 -1.2 0.4 -0.7 -1.1 -0.8 -0.0 -0.4 1.2
Heel bone mineral density (BMD) T-score, automated (right) 0.7 1.5 5.0 2.2 -0.9 -0.5 -0.8 1.3 0.9 1.4 -1.1
Ever unenthusiastic/disinterested for a whole week 1.0 1.2 3.6 1.5 -0.1 0.2 -0.6 0.7 -0.1 1.9 -1.7
Qualifications: None of the above 0.3 0.7 2.6 -1.6 1.1 -0.1 0.7 0.0 0.5 -0.8 -0.7
Financial difficulties in last 2 years 0.5 0.6 2.3 -0.3 -0.4 -0.0 -0.4 -0.2 -0.7 -1.4 1.5
Mouth/teeth dental problems 0.5 0.7 3.6 -0.5 0.3 -1.0 -1.9 -0.1 -0.9 -0.1 -0.3
Heart attack 0.5 0.6 1.5 -0.8 -0.7 -0.2 -1.0 -1.2 0.1 -1.0 0.3
Allergy 0.4 0.8 2.6 0.2 -1.6 -0.1 0.3 0.2 -0.8 0.9 -1.6
Pain all over the body in last month 0.8 0.9 2.5 0.2 -0.7 -1.0 0.0 1.0 1.6 -0.3 1.4
Diabetes (self-reported) 0.3 0.5 1.2 0.1 0.4 0.9 -0.8 -1.1 -0.2 0.0 -1.1
Hayfever/allergic rhinitis (self-reported) 0.7 0.9 2.1 -1.0 0.4 1.1 0.5 -1.4 -0.9 -1.1 1.0
Medication: Ramipril 1.1 1.4 5.1 0.4 -2.3 -1.8 -0.5 -0.1 -1.4 0.1 -0.3
Medication: Simvastatin 1.2 1.7 4.6 -0.3 -0.2 2.0 -2.1 -2.0 0.5 -0.7 0.7
Fluid intelligence score 0.2 0.4 0.9 0.9 0.7 0.3 -0.8 0.2 -0.6 -0.1 0.8
Illnesses of siblings 1.6 2.2 7.7 1.9 0.3 -1.3 -0.7 2.8 0.0 1.8 -1.0
Neuroticism score 0.4 0.8 1.8 -0.8 0.5 -0.5 -0.7 -0.3 -0.8 -1.3 1.3
Weight 0.2 1.0 6.3 -0.5 -0.1 0.2 0.3 -2.5 -0.3 0.9 -0.5
Impedance of arm (right) 0.2 0.9 2.5 -0.0 -1.4 -0.3 -0.7 0.8 -1.3 -1.6 -0.3
Arm fat percentage (right) 0.5 1.9 5.4 -1.1 -1.5 0.3 0.2 -2.3 -2.2 -0.8 -0.6
Trunk fat-free mass 0.2 1.4 5.3 -0.6 2.3 -0.6 -0.1 -1.4 0.5 1.6 0.8
Hip circumference 0.3 1.4 7.3 -0.2 -0.7 0.1 0.5 -2.7 -0.9 1.1 -0.9
Time employed in main current job 0.3 0.4 1.6 -0.1 0.8 -0.2 0.4 -0.4 -1.3 -0.1 -0.4
Alcohol intake versus 10 years previously 0.6 0.9 2.9 -1.7 0.1 0.5 1.0 -0.5 0.2 -1.5 0.8
Father’s age at death 0.4 0.5 1.3 0.2 0.5 -1.0 0.9 1.2 -0.3 0.9 -0.4
Worrier / anxious feelings 1.0 1.8 5.4 -0.7 0.4 -1.5 -1.3 1.4 -0.0 -1.5 2.3
Frequency of tiredness / lethargy in last 2 weeks 0.4 0.7 1.8 0.8 1.2 -0.9 0.3 -0.8 -1.3 0.4 0.2
Falls in the last year 0.1 0.1 0.3 0.5 -0.4 0.4 0.1 -0.0 0.3 -0.0 -0.3
Hair/balding pattern: Pattern 3 0.5 0.7 1.9 0.7 1.4 0.7 1.2 -1.0 -0.1 0.4 -0.1
Number of live births 0.2 0.3 1.1 -0.5 1.0 0.2 0.6 0.9 0.2 0.2 -0.4
Forced expiratory volume in 1-second (FEV1) 0.2 0.5 1.1 -1.0 0.8 0.4 -0.5 0.9 0.6 -0.2 1.0
Pulse rate 0.3 0.5 1.6 -0.3 0.2 0.1 0.7 -0.2 -1.0 0.7 -1.3
Happiness 0.2 0.2 0.6 0.6 0.2 -0.4 -0.3 0.8 -0.4 0.4 -0.4
Noisy workplace 1.2 1.5 5.3 -1.6 -0.3 1.0 1.2 -2.3 0.6 -0.9 0.7
Qualifications: A levels/AS levels or equivalent 0.5 1.1 1.7 0.4 -1.3 -1.0 1.3 -0.9 -1.3 0.9 -1.1
Serious illness, injury or assault of a close relative in last 2 years 0.5 0.6 1.5 1.2 0.3 -0.2 0.0 -0.5 0.0 1.2 -1.1
Mouth/teeth dental problems: Dentures 0.5 0.8 2.6 0.0 1.0 1.6 0.7 -0.7 1.2 0.4 -0.2
Asthma 0.3 0.6 1.7 -1.3 0.3 0.8 -0.9 -0.7 -0.3 -0.8 0.8
Medication: Ibuprofen (e.g. Nurofen) 1.8 2.2 6.1 -1.6 2.5 0.7 1.6 1.3 1.4 -1.0 1.0
Medication: Cholesterol lowering 0.8 1.3 3.9 0.1 -1.5 1.8 -2.0 -0.4 -0.1 -0.6 -0.5
Depression (self-reported) 0.8 1.0 5.7 -0.3 1.3 -0.3 -0.6 -2.4 -0.0 0.1 -0.3
Medication: Lansoprazole 0.5 0.6 1.6 1.0 -0.6 -1.3 -1.0 0.9 0.1 -0.0 -0.0
Prospective memory result 0.9 1.1 3.1 1.1 1.2 0.3 0.9 0.3 0.3 1.8 -1.4
Lung cancer (father) 0.5 0.6 1.4 -0.0 -0.0 1.1 1.2 -1.2 -0.3 -0.5 -0.4
Illnesses of mother 0.7 0.8 3.4 -0.4 -0.3 -1.6 -0.3 1.8 -0.0 0.2 -0.5
Forced expiratory volume in 1-second (FEV1), Best measure 0.1 0.4 2.2 -0.2 0.9 -0.2 -0.3 1.5 0.1 0.4 0.1
Pulse wave Arterial Stiffness index 1.5 1.8 4.9 -1.5 -1.9 -1.3 -0.8 0.1 0.2 -2.2 1.0
Impedance of arm (left) 0.2 0.8 2.2 0.2 -1.5 -0.1 0.3 0.7 -1.1 -1.3 -0.7
Arm fat mass (right) 0.3 1.4 6.5 -0.8 -0.8 0.2 0.5 -2.6 -1.7 0.1 -0.7
Trunk predicted mass 0.2 1.4 5.3 -0.7 2.3 -0.6 0.0 -1.4 0.5 1.5 0.8
Standing height 0.1 1.2 2.9 0.6 1.4 -0.6 -0.5 -1.0 1.3 1.7 0.7
Length of working week for main job 1.0 1.1 4.1 0.2 1.6 0.4 2.0 0.9 0.4 -0.1 0.9
Exposure to tobacco smoke at home 0.4 0.5 2.3 -0.4 0.3 -0.0 -1.5 -0.6 -0.9 -0.2 -0.3
Breastfed as a baby 0.8 1.0 6.0 0.2 -1.1 -2.5 -0.2 -0.4 -0.2 -0.0 -0.4
Tense / ‘highly strung’ 0.7 1.1 2.8 -1.0 -0.0 1.4 -1.7 -0.5 0.1 -1.3 1.1
Seen doctor (GP) for nerves, anxiety, tension or depression 0.2 0.4 1.6 -0.2 1.3 0.8 0.0 -0.1 -0.4 -0.8 0.1
Hair/balding pattern: Pattern 4 1.1 2.6 7.1 1.0 -1.4 1.0 -1.6 2.7 -0.7 2.0 -1.6
Birth weight of first child 0.2 0.3 0.7 -0.8 0.4 0.1 -0.5 0.6 0.7 0.6 0.5
Peak expiratory flow (PEF) 0.2 0.5 1.7 -1.1 0.1 1.3 0.6 0.0 0.1 -0.6 0.3
Pulse wave reflection index 1.7 2.1 5.0 -1.5 -1.7 -1.2 -1.5 0.0 -0.8 -2.2 1.5
Ever highly irritable/argumentative for 2 days 0.5 0.6 2.7 -0.1 -0.3 0.5 1.6 0.4 -1.0 0.5 -0.4
Loud music exposure frequency 2.0 2.2 6.5 -1.2 -2.1 0.2 -0.7 -1.7 -0.8 -2.5 1.2
Qualifications: O levels/GCSEs or equivalent 0.9 1.4 3.7 1.2 0.6 0.9 0.7 0.4 -0.9 1.9 -1.9
Mouth/teeth dental problems: Bleeding gums 0.5 0.6 4.2 0.1 -2.0 -0.1 0.4 0.5 -0.5 -0.1 0.1
Blood clot in the leg (DVT) 0.5 0.6 2.4 0.2 -1.1 -0.7 0.2 -1.5 0.3 -0.3 0.8
Medication: Paracetamol 0.2 0.4 0.9 -0.7 0.1 -0.1 0.0 -1.0 -0.7 -0.9 -0.7
Headache pain in last month 0.4 0.6 2.1 0.4 -0.4 -0.8 -0.3 -1.4 -1.3 -0.2 0.2
Medication for cholesterol, blood pressure or diabetes 1.1 1.8 7.2 -0.5 1.2 -1.3 2.7 0.5 -0.1 1.3 -1.3
Glaucoma (self-reported) 1.1 1.3 5.4 0.3 0.2 -0.0 -1.4 2.3 1.7 -0.2 0.3
Gout (self-reported) 0.8 1.1 3.5 -1.2 0.1 1.9 -0.6 -1.3 0.3 -1.3 0.3
Hypothyroidism/myxoedema (self-reported) 0.7 1.4 5.5 -0.2 1.7 0.4 -2.3 -1.0 -1.0 -0.3 -0.6
Medication: Amlodipine 1.0 1.4 6.7 1.3 -2.6 1.3 -0.2 -0.0 -0.2 1.1 -0.4
Medication: Ventolin 100micrograms inhaler 0.9 1.1 3.1 -1.4 0.8 1.2 -0.2 -1.7 -1.0 -0.5 -0.7
Birth weight 1.0 2.1 7.1 -1.4 2.7 -0.8 -0.4 -2.0 -1.7 -0.3 -0.3
Chronic bronchitis/emphysema (mother) 0.2 0.3 1.0 0.7 -1.0 -0.0 0.2 -0.2 0.1 0.6 -0.1
High blood pressure (siblings) 0.8 1.2 3.3 0.1 0.5 1.6 0.5 -1.7 -1.8 -0.2 -0.1
Forced vital capacity (FVC), Best measure 0.1 0.4 1.9 -0.3 0.3 -1.4 -0.0 -0.3 0.1 0.1 0.9
Body fat percentage 0.5 2.0 6.0 -0.6 -2.3 0.7 -0.0 -2.5 -1.5 -0.3 -1.2
Leg fat percentage (right) 0.3 1.2 2.8 -0.9 -1.7 0.5 -0.1 -1.7 -1.0 -0.4 -1.4
Arm fat-free mass (right) 0.2 1.2 4.0 -0.1 1.3 -0.2 -0.1 -2.0 0.3 1.9 -0.1
Exposure to tobacco smoke outside home 0.9 1.2 3.3 -1.0 -1.6 0.5 -0.3 -0.7 -0.2 -1.8 1.2
Comparative body size at age 10 0.2 0.7 3.0 -1.3 0.3 0.5 -0.3 -1.7 -0.1 0.0 -0.3
Number of full brothers 0.3 0.4 1.0 -0.1 -0.8 1.0 0.2 -0.1 0.3 0.7 -1.0
Worry too long after embarrassment 0.6 1.0 2.0 -0.6 -0.9 -1.4 -0.4 1.1 0.0 -1.2 1.3
Seen a psychiatrist for nerves, anxiety, tension or depression 0.2 0.2 1.0 0.6 0.2 -0.0 -0.0 0.4 1.0 0.3 -0.2
Wheeze or whistling in the chest in last year 1.2 2.1 4.2 -2.1 1.7 -0.4 -1.3 -1.3 -0.8 -1.9 1.3
Number of children fathered 1.6 1.8 6.1 -2.2 -0.5 -1.1 0.5 -0.5 1.1 -2.5 0.6
Reason for reducing amount of alcohol drunk: Health precaution 1.0 1.2 2.6 -1.0 0.2 -0.8 -0.4 -1.5 0.6 -1.6 1.5
Age at first live birth 0.9 1.5 2.8 -1.7 -1.7 -1.3 -1.2 -0.5 -0.5 -1.4 1.1
Pulse wave peak to peak time 1.6 1.9 6.0 1.6 1.8 1.3 0.9 -0.1 -0.2 2.5 -1.0
Health satisfaction 0.5 0.6 2.4 0.7 0.1 0.2 -1.2 -0.5 -1.5 0.2 -0.4
Shortness of breath walking on level ground 0.9 1.1 3.3 -0.7 -0.2 -0.6 -1.0 -1.5 0.6 -1.8 1.1
Qualifications: College or University degree 0.6 1.8 8.3 0.9 2.0 -2.9 0.2 0.5 -0.8 0.4 0.5
Eye problems/disorders: None of the above 0.6 0.7 1.9 -0.3 -1.4 -1.3 -1.3 0.0 0.3 -0.5 0.2
Mouth/teeth dental problems: Loose teeth 0.7 0.8 2.6 -0.7 1.0 0.1 0.1 -1.6 1.1 -1.1 0.1
Emphysema/chronic bronchitis 1.5 1.7 4.9 -1.1 0.6 -2.0 0.0 -0.5 0.1 -2.2 1.6
Medication for pain relief, constipation, heartburn 0.2 0.4 1.6 0.1 -1.2 0.4 -0.3 -0.5 0.3 0.8 -0.3
Neck or shoulder pain in last month 0.6 0.9 2.5 0.1 1.1 0.2 1.6 -1.4 -0.6 -0.8 0.2
Medication: Blood pressure 1.3 2.3 5.0 0.6 -2.2 1.1 -2.2 -1.2 -0.9 -1.3 1.7
Angina (self-reported) 0.7 0.9 4.7 0.6 0.6 0.2 -0.6 -2.2 -1.0 0.2 -0.1
Migraine (self-reported) 0.7 0.9 5.4 0.2 0.1 -0.1 -0.3 0.3 -0.7 1.0 -2.3
Medication: Ibuprofen 2.6 3.1 8.2 -1.4 2.1 0.2 1.7 1.8 2.9 -1.2 1.6
Medication: Allopurinol 0.6 0.8 2.9 -0.8 0.8 0.4 0.9 0.2 0.6 -1.7 1.0
Medication: Omeprazole 1.1 1.3 2.8 -0.8 1.0 -0.5 -1.0 -1.6 0.1 -1.7 1.4
Medication: Seretide 50 evohaler 1.3 1.5 5.4 -1.1 -0.2 -0.1 -1.6 -0.3 0.8 -1.5 2.3
Mean time to correctly identify matches 0.6 1.1 2.6 1.0 1.2 -0.2 1.5 1.6 0.4 0.7 -1.1
Heart disease (mother) 0.5 0.6 2.0 0.6 0.3 1.4 -0.5 0.0 0.0 1.4 -0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.6 0.7 1.3 1.0 -1.1 -1.1 0.2 1.1 -0.8 0.1 -0.8
Whole body fat mass 0.4 1.6 7.6 -0.4 -1.5 0.6 0.1 -2.8 -1.4 0.2 -0.8
Leg fat mass (right) 0.4 1.5 6.9 -0.9 -1.2 0.6 0.1 -2.6 -1.2 -0.0 -0.9
Arm predicted mass (right) 0.2 1.0 3.1 -0.1 1.3 -0.2 -0.0 -1.8 0.5 1.7 0.1
Pulse rate, automated reading 0.4 1.2 3.1 -0.1 -1.0 -0.8 -1.8 -1.4 -1.2 1.0 -0.4
Alcohol intake frequency. 0.6 1.3 4.0 -2.0 1.3 -0.7 0.5 0.7 0.6 -1.5 0.9
Comparative height size at age 10 0.3 1.7 3.8 -0.4 0.6 -1.8 -1.2 -1.8 2.0 1.2 0.1
Number of full sisters 0.9 1.1 4.1 -1.7 0.4 -0.4 0.9 -0.3 0.5 -2.0 0.6
Suffer from ‘nerves’ 0.3 0.5 1.8 0.3 0.8 -0.5 -0.3 1.3 0.4 -0.8 0.9
Overall health rating 0.6 1.2 3.2 1.1 -0.9 -0.7 -1.0 -0.9 -1.8 -1.2 0.7
Chest pain or discomfort 1.0 1.4 3.1 -1.5 -0.6 -1.1 0.6 -1.4 -0.9 -1.8 1.0
Had major operations 0.9 1.0 2.3 0.1 -1.5 -0.9 -0.9 -0.6 1.3 -0.7 1.3
Age at last live birth 0.6 0.9 1.8 -0.2 -1.3 0.6 -0.7 -1.1 -1.2 0.2 -1.2
Family relationship satisfaction 0.4 0.5 1.3 0.8 0.3 -0.2 0.8 -0.7 -0.2 0.9 -1.1
Leg pain on walking 1.0 1.3 3.8 1.2 0.9 -0.2 1.9 -1.6 -0.7 0.7 -0.9
Qualifications: NVQ or HND or HNC or equivalent 0.6 0.7 1.7 -0.3 -1.3 0.5 -1.0 0.3 0.9 -0.7 1.0
Commuting to job workplace: Car/motor vehicle 0.4 0.5 1.2 -0.3 0.6 0.1 -1.1 -0.8 0.9 0.4 -0.7
Illness, injury, bereavement, stress in last 2 years 0.3 0.4 0.9 -0.6 -0.7 -0.6 0.9 -0.8 -0.2 -0.5 0.2
Medication: Aspirin 0.8 1.1 5.8 0.3 -0.5 0.0 -2.4 -1.3 -0.5 0.5 -0.4
Supplements: Vitamin C 1.4 1.6 4.9 1.7 0.1 0.3 0.8 2.2 2.0 0.6 0.0
Knee pain experienced in last month 0.5 0.9 4.7 0.2 1.3 0.5 2.2 0.2 -0.3 0.2 -0.1
Hypertension (Self-reported) 1.0 2.7 9.7 1.0 -1.3 1.1 -3.1 -0.9 -2.5 -0.4 1.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 1.5 1.7 6.5 -0.8 0.5 -0.8 -1.0 0.3 1.9 -1.1 2.5
Illnesses of father: Heart disease 0.6 0.9 2.7 0.6 -0.2 0.4 -0.4 -1.6 -0.8 1.6 -0.7
Illnesses of siblings: Diabetes 0.5 0.6 2.1 -1.2 -0.2 -0.1 0.2 -1.5 0.5 -1.1 0.2
Smoking status: Previous 0.6 0.9 3.6 -0.6 -0.6 0.9 -1.5 -1.9 -0.2 -0.0 -0.1
Forced expiratory volume in 1-second (FEV1), predicted 0.3 0.7 2.0 0.6 1.2 0.3 -1.0 -1.4 0.2 0.7 0.0
Whole body fat-free mass 0.2 1.1 3.7 -0.7 1.6 -0.4 0.0 -1.9 0.1 1.3 0.5
Leg fat-free mass (right) 0.2 1.2 7.1 -0.7 1.0 -0.1 0.1 -2.7 -0.6 0.8 0.4
Arm fat percentage (left) 0.6 2.3 6.7 -1.1 -1.7 0.5 0.7 -2.6 -2.2 -0.8 -0.8
Average weekly red wine intake 0.3 0.5 2.1 0.2 -0.2 -0.7 -0.1 0.2 1.2 -0.1 1.4
Handedness (chirality/laterality): Left-handed 1.1 1.3 5.7 -1.1 -1.3 -0.2 -2.4 0.6 0.2 0.6 -0.9
Mood swings 0.7 1.2 3.4 -1.4 1.0 -0.5 -0.2 0.0 0.0 -1.6 1.8
Loneliness, isolation 0.5 0.7 2.2 0.9 0.4 -0.7 0.1 -0.8 -1.5 0.7 -0.8
Long-standing illness, disability or infirmity 1.0 1.5 5.5 -0.3 0.1 -0.5 -1.9 -2.3 -0.8 -1.4 0.7
Ever had bowel cancer screening 0.8 1.0 3.9 0.9 1.2 0.8 0.1 0.4 0.2 0.8 -2.0
Diabetes diagnosed by doctor 0.3 0.4 1.2 -0.0 -0.1 1.1 -0.3 -1.1 -0.0 -0.6 -0.7
Ever had stillbirth, spontaneous miscarriage or termination 0.4 0.5 1.2 0.3 -0.4 -1.1 -1.1 0.6 0.6 -0.1 0.7
Friendships satisfaction 0.7 0.8 1.6 1.3 1.2 -0.9 0.4 -1.0 -1.2 -0.2 -0.5
Qualifications: nursing, teaching 0.7 1.1 4.4 0.7 -1.4 -2.1 0.2 -1.4 -0.6 -0.0 -0.2
Commuting to job workplace: Walk 0.7 0.7 1.7 -1.3 0.3 0.3 1.0 0.3 -1.1 -0.8 1.0
Eye problems/disorders: Cataract 1.3 1.5 4.7 0.4 0.1 0.6 2.2 -1.1 -1.8 0.6 -1.4
Mouth/teeth dental problems: Mouth ulcers 0.9 1.5 5.0 0.5 -0.4 -1.1 1.0 -0.7 1.3 -1.4 2.2
Medication for cholesterol 1.5 2.3 8.5 -0.6 -2.9 -1.8 2.2 -0.6 0.3 0.2 -0.8
Medication: Laxatives (e.g. Dulcolax, Senokot) 1.0 1.2 2.4 1.5 1.5 0.3 0.8 -0.4 -0.1 1.5 -1.4
Back pain experienced in last month 0.4 0.6 1.6 0.2 1.1 0.6 1.0 1.3 -0.6 0.3 -0.7
Mineral and other dietary supplements 0.6 0.8 2.2 -0.4 0.4 1.2 -1.5 1.2 -0.8 -0.1 -0.2
Breast cancer (self-reported) 0.3 0.3 1.1 0.3 0.4 -1.1 0.9 -0.5 -0.6 -0.1 -0.0
Asthma (self-reported) 0.2 0.5 1.3 -1.1 0.4 0.7 -0.8 -0.7 -0.4 -0.7 0.4
Osteoporosis (self-reported) 0.5 0.6 1.7 0.7 0.5 -1.3 -0.7 -1.0 -1.0 0.4 -0.1
Osteoarthritis (self-reported) 1.2 1.5 3.8 1.7 -0.6 -0.2 0.3 -1.5 0.1 1.9 -1.7
Medication: Aspirin 1.0 1.3 5.9 0.7 -0.5 0.0 -2.4 -1.2 -0.7 0.9 -0.9
Medication: Gliclazide 1.9 2.2 4.4 1.6 0.9 0.9 -2.1 1.2 0.7 1.9 -1.9
Illnesses of father: None of the above (group 1) 0.5 0.7 1.2 -1.1 1.1 0.7 0.8 0.4 0.5 -1.1 0.2
Smoking status: Current 0.4 0.7 2.1 -0.8 0.1 0.3 -0.5 1.5 0.7 -1.3 -0.1
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.3 0.6 1.6 0.5 -1.0 0.3 0.3 1.2 1.0 0.6 0.7
Whole body water mass 0.2 1.2 3.9 -0.6 1.8 -0.4 0.0 -2.0 0.0 1.4 0.5
Leg predicted mass (right) 0.2 1.2 6.8 -0.6 1.0 -0.1 0.1 -2.6 -0.6 0.8 0.4
Arm fat mass (left) 0.4 1.6 7.3 -0.7 -0.8 0.3 0.8 -2.7 -1.7 0.2 -0.9
Number of self-reported non-cancer illnesses 0.9 1.6 4.1 -0.2 0.6 1.2 -1.8 -2.0 -0.7 -1.5 1.0
Average weekly champagne plus white wine intake 0.4 0.6 1.7 0.8 0.3 -0.5 0.6 -1.2 -0.1 0.6 1.3
Miserableness 0.1 0.3 0.8 -0.5 0.3 0.6 -0.5 0.9 0.2 0.5 -0.0
Guilty feelings 0.6 0.9 3.0 0.4 0.7 1.1 1.7 -0.6 -0.5 0.9 -0.9
Wears glasses or contact lenses 0.7 0.8 3.3 -0.0 -0.2 0.6 0.9 0.2 1.8 -0.7 1.1
Ever taken oral contraceptive pill 0.5 0.6 2.2 -0.5 0.0 -0.0 0.8 1.5 1.3 0.1 0.2
Hearing aid user 0.9 1.0 5.9 0.1 -0.5 -0.8 -0.8 0.8 2.4 0.5 0.1
Mother’s age at death 0.5 0.6 1.9 -0.1 -0.1 -0.1 -1.4 0.7 0.9 0.7 -1.2
Financial situation satisfaction 0.5 0.7 2.5 -0.5 0.8 0.1 -1.6 -0.0 0.1 -0.5 1.3
Tinnitus: Yes, now most or all of the time 0.4 0.4 1.5 -0.4 0.0 -0.1 -1.0 1.2 0.7 0.4 -0.1
Commuting to job workplace: Public transport 0.6 0.7 2.9 0.8 1.3 -0.1 0.5 -0.1 -1.7 0.4 -0.6
Eye problems/disorders: Glaucoma 0.8 1.0 5.3 -0.2 0.3 0.2 -1.3 2.3 0.4 -0.5 0.6
Medication: Blood pressure 0.9 1.8 5.4 1.9 -0.2 0.6 -2.3 -0.4 -2.0 0.7 -0.1
Pain type(s) experienced in last month: Hip pain 0.2 0.3 1.1 0.4 0.0 0.1 0.2 -0.6 1.0 -0.5 0.6
Supplements: Fish oil (including cod liver oil) 0.7 0.9 4.0 0.3 -0.2 -0.1 2.0 -0.8 1.3 -0.5 0.7
High cholesterol (Self-reported) 1.0 1.7 4.4 -0.7 1.5 2.1 -2.1 -1.1 0.6 -0.8 -0.2
Medication: Bendroflumethiazide 0.4 0.6 1.5 0.9 -0.9 -0.6 -1.2 0.1 0.5 0.6 0.8
Medication: Paracetamol 0.1 0.2 0.7 -0.2 0.3 0.1 -0.8 -0.8 0.2 -0.4 -0.4
Medication: Lisinopril 0.4 0.5 1.5 0.3 0.7 1.1 -0.6 -0.0 -1.2 -0.2 -0.4
Medication: Atorvastatin 0.7 0.9 3.1 -0.2 1.2 1.6 -1.8 0.2 -0.1 -0.5 -0.1
Illnesses of father: High blood pressure 1.5 1.9 4.5 1.5 -0.3 0.4 -0.5 1.5 -1.3 2.1 -2.1
Alcohol drinker status: Never 0.8 0.9 4.1 0.0 2.0 -1.5 -0.8 0.2 -0.1 0.5 -0.5
Ever smoked 0.3 0.6 2.1 -0.3 -1.1 0.3 0.1 -1.5 0.4 -0.8 -0.7
Basal metabolic rate 0.2 1.0 4.3 -0.7 1.3 -0.4 0.1 -2.1 -0.2 1.2 0.3
Leg fat percentage (left) 0.4 1.3 4.2 -0.6 -1.4 0.9 -0.0 -2.1 -1.0 -0.3 -1.4
Arm fat-free mass (left) 0.3 1.3 4.2 -0.0 1.8 -0.5 -0.3 -1.6 0.6 2.0 0.0
Number of operations (self-reported) 0.3 0.4 1.1 0.5 -0.0 1.0 0.4 -1.1 -0.3 0.5 0.9
Average weekly beer plus cider intake 0.4 0.6 2.1 0.3 -0.2 1.4 -0.1 0.1 0.3 1.2 -1.1
Irritability 0.9 1.6 4.0 -1.6 0.9 0.8 0.4 -1.3 -1.2 -1.2 2.0
Risk taking 0.7 1.1 4.9 -0.1 -0.3 -0.5 0.5 -0.9 0.7 -1.3 2.2
Ever had prostate specific antigen (PSA) test 0.9 1.1 3.3 -0.9 -1.8 -1.2 0.1 0.2 0.1 -1.8 0.2
Fractured/broken bones in last 5 years 0.8 1.0 2.7 0.4 1.6 0.5 0.3 -0.8 1.4 1.6 -0.1
Age started oral contraceptive pill 1.4 1.8 6.2 1.0 0.6 0.8 0.5 -2.5 -1.7 1.0 -1.4
Diastolic blood pressure, automated reading 0.8 2.5 8.8 -0.0 -2.2 -0.5 -1.3 -3.0 -1.1 -0.9 1.6
Ever depressed for a whole week 0.6 0.7 1.9 1.4 -0.5 1.0 -0.9 0.8 0.1 1.0 -0.5
Unable to work because of sickness or disability 0.8 1.1 4.2 0.8 -2.1 -0.7 -1.7 -0.1 -0.1 0.2 0.5
Commuting to job workplace: Cycle 0.7 0.8 3.3 0.2 0.0 -1.1 1.8 0.5 -1.1 0.1 -0.5
Myopia 0.5 0.7 2.3 1.5 -1.0 0.3 -0.7 -1.1 0.2 0.1 0.1
Vascular/heart problems diagnosed by doctor 0.8 2.3 7.1 -1.2 1.3 -1.2 2.7 0.7 2.0 0.2 -1.4
Cholesterol lowering medication 1.7 2.5 8.2 -0.3 2.9 2.1 -1.5 -2.1 0.5 -0.4 0.3
Medication: Omeprazole (e.g. Zanprol) 2.1 2.6 8.2 -1.5 1.0 -0.6 -0.1 -2.9 -1.0 -2.3 1.6
Pain experienced in last month 0.7 1.2 2.3 -1.5 -1.1 0.8 -1.5 -0.5 0.7 -1.2 1.1
Supplements: Calcium 1.1 1.2 3.2 1.5 0.2 -1.8 0.1 -0.6 -0.7 1.3 -1.4
Basal cell carcinoma (self-reported) 0.8 1.0 3.3 1.1 -0.1 -0.4 0.8 0.4 -0.9 1.3 -1.8
Heart attack/myocardial infarction (self-reported) 0.5 0.6 1.5 -0.9 -0.8 -0.1 -0.9 -1.2 -0.3 -1.1 0.3
Deep venous thrombosis (DVT) (self-reported) 0.6 0.7 2.5 0.3 -1.3 -0.8 0.0 -1.6 0.5 -0.2 0.8
Heart disease (siblings) 0.8 1.0 5.2 -0.9 -0.3 0.4 -0.1 -0.8 2.3 -0.7 0.7
Alcohol drinker status: Previous 2.3 2.6 9.1 -2.5 -0.2 -0.7 0.5 -1.1 -0.0 -3.0 1.9
Pack years of smoking 0.7 1.0 1.8 -1.2 1.1 0.7 -0.1 -0.7 1.2 -1.4 0.9
Impedance of whole body 0.2 1.0 3.6 0.9 -1.9 0.3 -0.6 1.1 -0.4 -0.8 -0.8
Leg fat mass (left) 0.4 1.7 8.3 -0.7 -1.2 0.8 0.0 -2.9 -1.3 0.0 -0.9
Arm predicted mass (left) 0.2 1.2 3.7 -0.0 1.7 -0.5 0.1 -1.6 0.5 1.9 0.0