TWAS hub - PDIA5

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Artery Tibial	0.1114	0.0386	0.00034	0.001	NA	0.029	NA	0.020	2.4e-01	NA	2.4e-03	NA	9.4e-03
2	GTEx	Testis	0.1710	0.0730	0.00990	0.111	NA	0.015	NA	0.067	1.2e-05	NA	6.8e-02	NA	6.7e-04
3	YFS	Blood	0.0287	0.0098	0.00026	0.025	0.011	0.020	0.018	0.022	1.1e-08	9e-05	2.8e-07	1.4e-06	7.5e-08

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
Blood Platelet Count	12.7	146.9	400.0	6.3	0.9	20.0
Qualifications: nursing, teaching	4.2	6.5	8.9	-3.0	2.2	-2.4
Birth weight	4.1	9.0	22.4	4.7	1.8	-1.1
Medication: Seretide 50 evohaler	3.8	4.4	7.1	-2.5	-0.3	-2.7
Diabetes (mother)	3.6	4.6	7.1	-2.7	2.5	-0.6
Illnesses of mother	3.1	3.8	5.4	2.3	-1.7	1.8
Birth weight of first child	2.9	5.2	15.4	3.9	-0.3	-0.2
Friendships satisfaction	2.8	3.5	5.3	2.3	-2.1	-0.9
Number of live births	2.4	3.4	4.0	2.0	2.0	1.5
Medication: Laxatives (e.g. Dulcolax, Senokot)	2.3	2.7	5.3	-2.3	0.2	1.7
Average weekly spirits intake	2.1	2.6	5.7	2.4	0.9	1.2
Diabetes (father)	2.1	2.6	5.2	-2.3	0.6	-1.5
Financial difficulties in last 2 years	2.0	2.6	5.7	0.6	-1.4	2.4
Ever had bowel cancer screening	2.0	2.3	3.1	-1.8	1.5	-1.3
Mother’s age at death	2.0	2.5	3.3	-1.3	1.8	-1.6
Alcohol drinker status: Previous	2.0	2.3	5.8	0.4	-0.9	2.4
Glaucoma (self-reported)	1.9	2.2	3.9	-1.5	-2.0	-0.7
Ovarian Cancer	1.7	2.2	2.6	-1.6	1.2	-1.6
Supplements: Zinc	1.7	1.9	4.0	1.0	0.8	-2.0
Fed-up feelings	1.7	3.2	7.1	2.7	1.4	0.5
Medication: Lansoprazole	1.7	1.9	2.4	-1.3	-1.2	1.6
Emphysema/chronic bronchitis	1.7	1.9	3.3	-1.8	1.5	-0.5
Qualifications: NVQ or HND or HNC or equivalent	1.7	2.1	3.8	0.8	-1.3	2.0
Osteoporosis (self-reported)	1.7	2.1	2.2	1.4	-1.5	-1.5
Chest pain or discomfort	1.6	2.2	6.7	0.0	-0.2	-2.6
Had major operations	1.6	1.9	4.0	1.3	2.0	0.3
Major Depression (MDD)	1.5	1.8	4.2	-2.0	-0.4	-1.1
Coronary Artery Disease (CAD)	1.5	1.8	3.9	-0.8	-2.0	1.0
Blood White Count	1.5	11.1	21.3	4.6	0.7	3.4
Eye problems/disorders: Diabetes related eye disease	1.5	1.7	2.6	-0.2	1.6	-1.6
Medication: Atenolol	1.5	1.9	4.5	0.8	-2.1	-0.8
Breastfed as a baby	1.5	1.9	5.3	-0.0	0.5	-2.3
Leg pain on walking	1.5	1.9	3.0	-1.7	0.0	-1.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.5	1.8	3.7	-1.2	1.9	0.4
Rheumatoid Arthritis	1.4	1.9	2.2	-1.5	-1.4	-1.2
Sensitivity / hurt feelings	1.4	2.4	5.0	-2.2	-1.3	-0.8
Angina	1.4	1.9	3.7	-0.9	-1.0	-1.9
Townsend deprivation index at recruitment	1.4	2.0	3.3	1.8	-1.3	0.9
Tinnitus: Yes, but not now, but have in the past	1.4	1.5	3.4	1.9	0.6	0.9
Mouth/teeth dental problems: Dentures	1.4	2.4	3.5	-1.2	-1.9	1.5
Forced expiratory volume in 1-second (FEV1), predicted	1.4	2.8	5.7	-2.4	-0.8	1.5
Breast cancer (self-reported)	1.4	1.7	4.0	-1.0	-0.4	-2.0
Crohns Disease (2012)	1.3	2.0	5.6	0.6	0.4	2.4
Ulcerative Colitis	1.3	1.9	3.0	1.6	0.6	1.7
Type 2 Diabetes (T2D) (2018)	1.3	2.5	4.2	-2.0	1.2	1.3
Stomach or abdominal pain in last month	1.3	1.6	3.2	-0.8	-0.9	-1.8
Had menopause	1.3	1.6	3.2	-0.5	1.8	-1.1
Angina (self-reported)	1.3	1.8	3.1	-0.9	-1.2	-1.8
Alcohol intake frequency.	1.3	3.0	4.6	2.1	-0.1	2.1
Family relationship satisfaction	1.3	1.6	2.3	1.2	-1.0	-1.5
Age started oral contraceptive pill	1.3	1.7	3.5	-1.2	0.4	-1.9
Commuting to job workplace: Cycle	1.3	1.6	3.0	-1.1	-1.7	-0.7
Schizophrenia vs Biploar Disorder	1.2	1.6	4.4	-0.5	-2.1	-0.5
Alzheimer’s Disease (including proxy)	1.2	1.7	2.8	-1.5	0.1	-1.7
Triglycerides	1.2	2.0	3.6	-1.9	-0.4	-1.5
Hearing difficulty/problems: Yes	1.2	1.8	4.2	2.1	-0.3	1.1
Vitamin and mineral supplements	1.2	1.6	4.6	-0.1	-0.3	2.2
Medication: Levothyroxine sodium	1.2	2.1	4.2	2.0	1.1	0.8
Sitting height	1.2	8.4	13.6	-3.7	-1.2	3.2
Depression (self-reported)	1.2	1.4	2.3	-1.4	-0.0	1.5
Number of children fathered	1.2	1.4	3.4	-1.9	0.6	-0.6
Eye problems/disorders: None of the above	1.2	1.4	2.5	-1.6	0.9	0.9
Pulse rate, automated reading	1.2	3.8	6.0	2.2	0.7	2.5
Unable to work because of sickness or disability	1.2	1.5	4.0	-0.7	-0.0	2.0
HDL Cholesterol	1.1	1.8	4.2	1.1	-2.0	-0.0
Multivitamins +/- minerals	1.1	1.4	3.2	1.1	-0.0	-1.8
Medication: Ventolin 100micrograms inhaler	1.1	1.4	3.5	-1.9	-0.4	-0.8
Comparative height size at age 10	1.1	6.0	13.8	-3.7	-2.0	0.5
Number of full sisters	1.1	1.3	3.1	0.6	-1.8	0.6
Commuting to job workplace: Walk	1.1	1.2	2.9	-0.6	1.7	-0.6
Ever smoked	1.1	1.9	3.9	1.3	2.0	0.5
Myopia	1.1	1.6	4.6	-0.2	-0.3	-2.1
Severe depression (siblings)	1.0	1.1	2.4	-1.6	-0.1	-1.0
Impedance of leg (right)	1.0	5.0	7.9	-1.4	2.8	2.3
Impedance of leg (left)	1.0	4.9	6.0	-1.7	2.4	2.5
Waist circumference	1.0	3.6	9.2	-1.1	-3.0	-0.6
Mouth/teeth dental problems	1.0	1.5	2.7	1.7	1.4	-0.1
Father’s age at death	1.0	1.4	2.6	-1.2	-0.3	-1.6
Standing height	1.0	10.1	20.9	-4.6	-1.2	2.8
Ever highly irritable/argumentative for 2 days	1.0	1.2	3.4	1.8	0.2	0.5
Wheeze or whistling in the chest in last year	1.0	1.9	4.2	-0.8	-0.8	-2.1
Financial situation satisfaction	1.0	1.2	3.5	1.9	-0.3	0.2
Bipolar Disorder (2018)	0.9	1.4	2.6	1.2	0.4	1.6
Alzheimer’s Disease (in father)	0.9	1.0	2.5	-0.4	-0.6	-1.6
Reaction Time	0.9	1.7	4.0	-0.0	-1.0	2.0
Age at First Birth	0.9	1.4	3.3	0.8	-1.8	0.3
Qualifications: A levels/AS levels or equivalent	0.9	1.9	3.7	-1.9	1.3	-0.5
Chronic bronchitis/emphysema (mother)	0.9	1.1	1.7	-1.1	1.3	-0.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.9	1.0	1.8	1.4	-0.9	0.6
Eye problems/disorders: Cataract	0.9	1.1	2.0	1.4	-0.2	-1.1
Guilty feelings	0.9	1.4	2.1	-1.4	1.3	-0.7
Risk taking	0.9	1.4	3.7	-0.6	-1.9	0.3
Worry (Nagel 2018)	0.8	1.8	3.0	-1.7	-1.5	-0.3
Lung FEV1/FVC ratio	0.8	3.8	8.5	0.9	-1.5	-2.9
Neuroticism	0.8	2.0	2.9	-1.7	-1.6	-0.8
Maternal smoking around birth	0.8	1.2	3.2	-0.4	0.4	-1.8
Bilateral oophorectomy (both ovaries removed)	0.8	0.9	1.5	-1.2	1.0	0.2
Serious illness, injury or assault to yourself	0.8	1.0	1.4	0.3	1.2	-1.2
Chronic bronchitis/emphysema (father)	0.8	1.0	1.9	0.8	1.4	0.5
Frequency of tenseness / restlessness in last 2 weeks	0.8	1.2	1.7	0.8	-1.1	1.3
Hearing difficulty/problems with background noise	0.8	1.2	2.8	1.7	-0.4	0.9
Pain all over the body in last month	0.8	0.9	1.7	1.0	-1.3	0.0
Medication: Ramipril	0.8	1.0	2.8	1.7	-0.2	0.3
Happiness	0.8	1.0	1.8	1.4	-1.0	-0.2
Pulse wave Arterial Stiffness index	0.8	0.9	1.9	-1.4	-0.6	0.7
Hypothyroidism/myxoedema (self-reported)	0.8	1.6	3.2	1.8	1.2	0.5
High blood pressure (siblings)	0.8	1.2	1.3	1.0	1.1	1.1
Comparative body size at age 10	0.8	2.2	3.7	-1.9	-1.1	-1.4
Shortness of breath walking on level ground	0.8	0.9	2.4	-0.4	-1.5	-0.5
Age at last live birth	0.8	1.1	2.1	0.4	-1.5	1.0
Smoking status: Previous	0.8	1.2	2.3	1.5	0.5	1.0
Mouth/teeth dental problems: Mouth ulcers	0.8	1.3	3.8	-1.9	0.1	0.4
Pain type(s) experienced in last month: Hip pain	0.8	1.0	1.5	0.1	-1.2	1.2
Number of operations (self-reported)	0.8	1.2	2.6	-0.7	1.6	-0.6
Ever had prostate specific antigen (PSA) test	0.8	0.9	1.4	-0.9	-1.2	0.7
Neuroticism (Nagel 2018)	0.7	1.6	3.5	-1.9	-0.9	-0.7
Alzheimer’s Disease (in mother)	0.7	0.8	1.1	-0.7	1.0	-1.0
Respiratory disease	0.7	1.5	2.4	-1.4	0.1	-1.6
Chronotype (morning person)	0.7	1.6	3.9	-2.0	-0.4	0.8
Other serious medical condition/disability diagnosed by doctor	0.7	0.9	2.5	0.3	0.3	-1.6
Ever had hysterectomy (womb removed)	0.7	0.8	1.9	-1.4	0.3	-0.7
Medication: Metformin	0.7	1.0	1.7	-1.3	-1.1	0.5
Frequency of unenthusiasm / disinterest in last 2 weeks	0.7	1.0	2.1	1.5	0.6	-0.7
Age when periods started (menarche)	0.7	1.8	3.6	1.9	-0.1	1.3
Supplements: Glucosamine	0.7	0.9	1.3	1.1	0.9	-0.8
Diverticular disease/diverticulitis (self-reported)	0.7	0.9	2.4	0.3	1.6	-0.4
Trunk fat mass	0.7	2.9	6.4	-1.4	-2.5	0.5
Number of incorrect matches in round	0.7	1.2	1.8	-1.3	-0.7	-1.1
Allergy	0.7	1.7	3.5	1.2	0.4	1.9
Illnesses of siblings	0.7	1.0	2.1	-0.7	-0.7	-1.4
Weight	0.7	3.4	7.6	-1.6	-2.8	0.2
Hip circumference	0.7	3.1	6.1	-1.5	-2.5	0.9
Arm fat mass (right)	0.7	2.8	7.2	-1.0	-2.7	-0.3
Seen doctor (GP) for nerves, anxiety, tension or depression	0.7	1.1	1.5	-1.2	0.9	0.9
Headache pain in last month	0.7	1.2	3.2	-0.1	-0.6	1.8
Heart disease (mother)	0.7	0.9	2.3	-1.5	0.1	0.6
Whole body fat mass	0.7	2.9	6.8	-1.3	-2.6	0.4
Leg fat-free mass (right)	0.7	4.0	10.2	-1.3	-3.2	-0.2
Smoking status: Current	0.7	1.2	2.2	-1.1	0.0	-1.5
Leg predicted mass (right)	0.7	3.9	9.9	-1.3	-3.2	-0.1
Arm fat mass (left)	0.7	2.7	7.1	-0.9	-2.7	-0.5
Wears glasses or contact lenses	0.7	0.8	2.1	-0.4	0.4	-1.4
Eye problems/disorders: Glaucoma	0.7	0.9	2.3	-0.0	-1.5	-0.5
Supplements: Fish oil (including cod liver oil)	0.7	0.9	2.6	-0.2	-0.4	-1.6
Medication: Bendroflumethiazide	0.7	1.0	1.6	1.1	-0.6	1.3
Medication: Atorvastatin	0.7	0.8	1.7	-0.6	0.6	-1.3
Illnesses of father: High blood pressure	0.7	0.9	1.5	1.2	0.3	1.0
Alcohol drinker status: Never	0.7	0.8	2.2	0.0	-0.4	1.5
Breast Cancer	0.6	1.4	2.5	-1.3	1.6	-0.2
LDL Cholesterol	0.6	0.9	1.6	-1.0	-1.3	-0.1
Heel T-Score	0.6	4.8	5.8	-2.4	2.4	-1.8
Ever used hormone-replacement therapy (HRT)	0.6	0.8	1.2	-1.1	0.9	0.7
Leg fat-free mass (left)	0.6	3.4	8.7	-1.3	-2.9	-0.1
Trunk fat percentage	0.6	2.3	5.7	-0.9	-2.4	0.5
Leg predicted mass (left)	0.6	3.4	8.6	-1.3	-2.9	-0.1
Past tobacco smoking	0.6	1.1	1.8	-1.2	-1.4	-0.3
Medication: Simvastatin	0.6	0.9	1.5	1.0	-1.2	0.3
Noisy workplace	0.6	0.7	1.0	1.0	-1.0	-0.4
Prospective memory result	0.6	0.8	2.3	-0.1	0.2	1.5
Exposure to tobacco smoke at home	0.6	0.7	1.9	-0.1	-0.2	1.4
Qualifications: O levels/GCSEs or equivalent	0.6	1.0	1.9	-0.7	-0.8	-1.4
Blood clot in the leg (DVT)	0.6	0.8	1.6	0.4	-1.3	-0.8
Medication: Amlodipine	0.6	0.8	1.2	1.0	-0.5	-1.1
Mouth/teeth dental problems: Loose teeth	0.6	0.8	1.3	-0.7	-0.7	-1.1
Medication for cholesterol	0.6	1.0	1.9	-0.3	0.9	-1.4
Medication: Gliclazide	0.6	0.6	1.0	-1.0	-0.9	-0.2
Basal metabolic rate	0.6	3.2	6.6	-1.7	-2.6	0.4
Deep venous thrombosis (DVT) (self-reported)	0.6	0.8	1.4	0.3	-1.2	-0.9
Crohns Disease (2017)	0.5	1.1	2.8	-0.7	0.4	1.7
Irritable Bowel Disease (IBD)	0.5	1.2	3.1	-0.1	0.7	1.8
Bipolar Disorder (2011)	0.5	0.5	1.3	0.6	-1.1	0.1
Fasting Glucose	0.5	0.6	1.0	1.0	0.2	0.9
BMI	0.5	2.9	5.9	-1.3	-2.4	-1.1
Systolic Blood Pressure	0.5	2.5	3.8	-0.8	-1.8	-1.9
Hand grip strength (left)	0.5	1.2	3.2	-0.7	1.8	-0.0
Frequency of depressed mood in last 2 weeks	0.5	0.6	1.4	0.0	-1.2	0.7
Systolic blood pressure, automated reading	0.5	1.5	1.9	-1.0	-1.4	-1.3
Taking other prescription medications	0.5	0.8	1.3	-1.1	-0.3	-1.2
Qualifications: CSEs or equivalent	0.5	0.6	1.8	0.1	-0.0	1.4
High blood pressure (mother)	0.5	0.6	1.3	0.7	0.4	-1.1
Had other major operations	0.5	0.6	1.2	-1.1	0.2	-0.6
Arm fat percentage (right)	0.5	1.9	5.4	-0.1	-2.3	-0.4
Time employed in main current job	0.5	0.5	0.8	0.7	0.5	-0.9
Loud music exposure frequency	0.5	0.6	1.4	1.2	0.3	-0.4
Number of full brothers	0.5	0.6	0.8	0.9	0.9	0.4
Worry too long after embarrassment	0.5	0.9	1.3	-1.2	-1.1	0.2
Pulse wave peak to peak time	0.5	0.6	1.0	1.0	0.8	-0.4
Qualifications: College or University degree	0.5	1.7	2.7	-1.6	0.2	-1.6
Suffer from ‘nerves’	0.5	0.8	2.3	-1.5	-0.4	-0.2
Illness, injury, bereavement, stress in last 2 years	0.5	0.6	1.5	1.2	0.2	0.3
Supplements: Vitamin C	0.5	0.6	1.1	-0.4	0.7	-1.0
Whole body fat-free mass	0.5	2.6	5.2	-1.6	-2.3	0.3
Arm fat percentage (left)	0.5	1.8	5.2	-0.3	-2.3	-0.4
Mineral and other dietary supplements	0.5	0.7	2.0	-0.2	-0.3	1.4
Average weekly champagne plus white wine intake	0.5	0.7	1.5	-0.1	-1.2	-0.8
Commuting to job workplace: Public transport	0.5	0.6	1.3	-0.6	1.1	0.4
Average weekly beer plus cider intake	0.5	0.8	1.5	-1.2	-0.6	0.6
Fractured/broken bones in last 5 years	0.5	0.6	1.2	0.8	-0.2	-1.1
Pain experienced in last month	0.5	0.9	2.1	0.7	1.4	-0.4
Impedance of whole body	0.5	2.6	3.9	-1.4	1.3	2.0
Ulcerative Colitis (UC)	0.4	0.7	1.5	0.6	0.5	1.2
Mean Putamen Volume	0.4	0.5	1.0	1.0	-0.6	-0.3
Lupus	0.4	0.6	1.5	-0.5	0.3	1.2
Type 2 Diabetes (T2D) (2012)	0.4	0.4	0.5	0.6	0.7	0.7
Height	0.4	7.2	13.0	-2.9	0.3	3.6
Current tobacco smoking	0.4	0.7	1.1	-1.0	0.0	-1.0
Body mass index (BMI)	0.4	1.9	4.8	0.2	-2.2	-0.9
Hayfever/allergic rhinitis (self-reported)	0.4	0.5	1.4	-1.2	0.2	0.1
Fluid intelligence score	0.4	0.8	1.1	-1.0	-1.1	-0.4
Medication: Ibuprofen (e.g. Nurofen)	0.4	0.5	1.3	-0.1	-1.2	0.4
Medication for cholesterol, blood pressure or diabetes	0.4	0.6	1.4	0.4	0.5	1.2
Gout (self-reported)	0.4	0.5	0.7	0.8	-0.6	-0.8
Body fat percentage	0.4	1.7	4.6	-0.6	-2.1	0.4
Medication for pain relief, constipation, heartburn	0.4	0.6	1.6	1.2	0.1	-0.5
Medication: Blood pressure	0.4	0.8	1.4	0.1	-1.0	-1.2
Medication: Omeprazole	0.4	0.5	1.3	-0.2	0.4	-1.2
Leg fat mass (right)	0.4	1.5	3.6	-0.9	-1.9	0.2
Asthma (self-reported)	0.4	0.7	1.7	0.2	-0.6	-1.3
Illnesses of father: None of the above (group 1)	0.4	0.5	1.2	1.1	0.5	0.2
Whole body water mass	0.4	2.4	5.0	-1.5	-2.2	0.3
Ever taken oral contraceptive pill	0.4	0.4	1.0	0.5	1.0	0.1
Tinnitus: Yes, now most or all of the time	0.4	0.5	1.2	-0.0	-0.4	-1.1
Arm fat-free mass (left)	0.4	2.1	3.5	-1.5	-1.9	0.7
Cholesterol lowering medication	0.4	0.6	1.6	-0.1	-1.3	-0.4
Leg fat mass (left)	0.4	1.7	4.2	-1.0	-2.0	0.3
Depression (Nagel 2018)	0.3	0.5	0.7	0.8	-0.8	0.5
Waist Hip Ratio (WHR)	0.3	1.3	2.3	-0.2	-1.5	-1.2
Allergy or Eczema	0.3	0.8	1.1	-1.0	-0.6	-1.0
Hypothyroidism (self reported)	0.3	0.7	1.4	1.2	0.7	0.4
Lung FVC	0.3	1.4	2.7	0.4	1.2	-1.6
Number of treatments/medications taken	0.3	0.6	1.2	-0.8	0.0	-1.1
Medication for hormone replacement therapy	0.3	0.3	0.7	-0.0	-0.5	0.8
Medication: Co-codamol	0.3	0.3	0.6	0.4	-0.5	-0.8
Hayfever, allergic rhinitis or eczema	0.3	0.6	0.9	-0.9	-0.2	-1.0
Hair/balding pattern: Pattern 2	0.3	0.4	1.0	0.0	0.4	-1.0
Trunk fat-free mass	0.3	2.0	3.1	-1.8	-1.6	0.6
Worrier / anxious feelings	0.3	0.5	0.8	-0.9	-0.6	-0.7
Falls in the last year	0.3	0.4	0.7	0.0	-0.8	-0.8
Impedance of arm (left)	0.3	1.2	2.8	-1.7	0.3	0.9
Trunk predicted mass	0.3	1.9	3.1	-1.8	-1.5	0.5
Hair/balding pattern: Pattern 4	0.3	0.8	1.1	-0.9	1.1	-0.6
Medication: Paracetamol	0.3	0.5	0.7	-0.9	0.3	0.8
Arm fat-free mass (right)	0.3	1.5	2.4	-1.4	-1.6	0.4
Migraine (self-reported)	0.3	0.4	0.5	0.5	0.5	-0.7
Medication: Allopurinol	0.3	0.4	1.1	1.0	-0.1	-0.1
Arm predicted mass (right)	0.3	1.6	2.6	-1.5	-1.6	0.3
Medication: Aspirin	0.3	0.3	0.7	-0.9	-0.4	-0.4
Illnesses of siblings: Diabetes	0.3	0.3	0.7	0.4	-0.2	0.9
Long-standing illness, disability or infirmity	0.3	0.5	0.9	0.9	0.4	-0.6
Diabetes diagnosed by doctor	0.3	0.5	1.3	-1.2	-0.0	0.3
Back pain experienced in last month	0.3	0.5	1.1	-0.6	-1.0	0.3
Osteoarthritis (self-reported)	0.3	0.3	0.9	-0.3	-0.9	0.1
Number of self-reported non-cancer illnesses	0.3	0.5	0.9	-0.8	-0.3	-0.9
Medication: Blood pressure	0.3	0.6	1.0	1.0	-0.5	0.8
Irritability	0.3	0.6	1.0	-1.0	-0.6	-0.6
Ever depressed for a whole week	0.3	0.4	1.0	1.0	0.0	-0.1
Medication: Omeprazole (e.g. Zanprol)	0.3	0.4	0.6	-0.5	0.6	-0.8
Supplements: Calcium	0.3	0.3	0.5	-0.5	0.7	-0.3
Heart attack/myocardial infarction (self-reported)	0.3	0.4	0.6	0.3	-0.7	0.8
Arm predicted mass (left)	0.3	1.7	3.6	-1.2	-1.9	0.5
Schizophrenia (2018)	0.2	0.5	1.3	-0.4	-0.1	-1.1
Body Mass Index (BMI) (2010)	0.2	0.3	0.7	-0.4	0.8	0.1
Primary Biliary Cirrhosis	0.2	0.2	0.5	0.7	0.5	0.1
Smoking Status	0.2	0.5	0.7	0.8	0.4	-0.8
Hair Pigment	0.2	5.5	10.0	-3.2	-1.6	-2.0
Pack years adult smoking proportion	0.2	0.2	0.6	0.3	-0.1	-0.8
Hand grip strength (right)	0.2	0.6	1.6	-0.5	0.1	-1.3
High blood pressure	0.2	0.5	0.9	0.5	-1.0	-0.6
Ever unenthusiastic/disinterested for a whole week	0.2	0.3	0.3	0.5	-0.5	0.6
Qualifications: None of the above	0.2	0.4	0.8	0.9	0.4	0.5
Heart attack	0.2	0.3	0.5	0.1	-0.5	0.7
Diabetes (self-reported)	0.2	0.4	1.0	-1.0	-0.2	0.4
Neuroticism score	0.2	0.3	0.6	-0.8	-0.2	-0.6
Impedance of arm (right)	0.2	1.1	2.9	-1.7	0.1	0.6
Alcohol intake versus 10 years previously	0.2	0.3	0.6	0.8	0.2	0.5
Serious illness, injury or assault of a close relative in last 2 years	0.2	0.2	0.5	-0.2	0.7	0.4
Asthma	0.2	0.5	1.2	0.3	-0.4	-1.1
Medication: Cholesterol lowering	0.2	0.3	0.7	-0.8	0.3	-0.0
Lung cancer (father)	0.2	0.2	0.5	0.7	0.1	-0.4
Tense / ‘highly strung’	0.2	0.3	0.5	-0.5	-0.7	0.2
Peak expiratory flow (PEF)	0.2	0.5	0.8	0.9	-0.6	-0.5
Forced vital capacity (FVC), Best measure	0.2	0.7	1.4	-0.4	1.2	0.7
Seen a psychiatrist for nerves, anxiety, tension or depression	0.2	0.3	0.6	-0.4	0.4	0.8
Reason for reducing amount of alcohol drunk: Health precaution	0.2	0.3	0.4	0.3	-0.5	-0.6
Age at first live birth	0.2	0.3	0.6	-0.4	-0.8	0.4
Health satisfaction	0.2	0.3	0.8	-0.1	-0.3	-0.9
Medication: Ibuprofen	0.2	0.3	0.6	0.4	-0.3	0.8
Mean time to correctly identify matches	0.2	0.3	1.0	-0.0	-0.2	1.0
Overall health rating	0.2	0.4	0.8	0.2	-0.5	-0.9
Commuting to job workplace: Car/motor vehicle	0.2	0.2	0.4	-0.4	-0.6	0.0
Hypertension (Self-reported)	0.2	0.5	0.9	0.6	-1.0	-0.5
Illnesses of father: Heart disease	0.2	0.3	0.7	-0.3	0.1	-0.9
Average weekly red wine intake	0.2	0.3	0.5	0.6	-0.7	-0.1
Medication: Aspirin	0.2	0.3	0.8	-0.9	-0.2	-0.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.2	0.4	0.6	0.4	0.5	0.8
Miserableness	0.2	0.4	0.7	0.7	0.4	0.8
Hearing aid user	0.2	0.3	0.7	0.0	-0.4	0.8
High cholesterol (Self-reported)	0.2	0.4	1.2	-0.2	-1.1	0.3
Medication: Paracetamol	0.2	0.3	0.6	-0.8	0.3	0.3
Leg fat percentage (left)	0.2	0.6	1.5	-0.2	-1.2	0.4
Diastolic blood pressure, automated reading	0.2	0.7	1.2	1.1	-0.9	0.5
Basal cell carcinoma (self-reported)	0.2	0.3	0.5	-0.7	0.4	0.4
Heart disease (siblings)	0.2	0.3	0.5	-0.1	-0.7	-0.6
Pack years of smoking	0.2	0.3	0.8	0.3	-0.3	-0.9
Verbal and Numeric Reasoning (VNR)	0.1	0.1	0.3	-0.5	-0.1	-0.3
Prostate Cancer	0.1	0.1	0.3	0.1	-0.2	-0.6
Neuroticism (2016)	0.1	0.1	0.2	-0.3	-0.4	-0.4
Schizophrenia (2014)	0.1	0.1	0.3	0.6	-0.2	0.1
Blood Eosinophil Count	0.1	0.9	1.7	0.7	0.7	1.3
Blood Red Count	0.1	0.7	1.0	1.0	0.4	0.9
Cardiovascular Disease	0.1	0.3	0.6	0.1	-0.4	-0.8
Tanning	0.1	1.0	2.2	0.6	0.7	1.5
Relative age of first facial hair	0.1	0.2	0.4	-0.2	-0.5	0.6
Average weekly fortified wine intake	0.1	0.2	0.2	-0.4	-0.3	0.5
Relative age voice broke	0.1	0.2	0.4	-0.2	0.5	0.7
Nervous feelings	0.1	0.2	0.4	-0.1	-0.6	0.4
Forced vital capacity (FVC)	0.1	0.3	0.7	-0.8	0.5	0.0
Frequency of tiredness / lethargy in last 2 weeks	0.1	0.2	0.3	0.6	-0.5	0.1
Hair/balding pattern: Pattern 3	0.1	0.1	0.2	0.4	0.3	0.1
Pulse rate	0.1	0.1	0.2	-0.3	-0.4	0.4
Forced expiratory volume in 1-second (FEV1), Best measure	0.1	0.4	0.9	0.0	0.5	0.9
Length of working week for main job	0.1	0.1	0.4	0.6	0.2	-0.0
Pulse wave reflection index	0.1	0.2	0.2	-0.5	-0.4	0.4
Mouth/teeth dental problems: Bleeding gums	0.1	0.1	0.1	0.3	-0.2	-0.3
Leg fat percentage (right)	0.1	0.3	0.8	-0.1	-0.9	0.4
Exposure to tobacco smoke outside home	0.1	0.2	0.4	0.2	0.6	0.3
Neck or shoulder pain in last month	0.1	0.2	0.5	-0.2	-0.7	0.2
Knee pain experienced in last month	0.1	0.2	0.3	-0.6	0.4	0.2
Handedness (chirality/laterality): Left-handed	0.1	0.1	0.2	-0.3	0.4	0.0
Mood swings	0.1	0.2	0.4	-0.6	-0.4	-0.2
Loneliness, isolation	0.1	0.1	0.3	0.2	0.5	0.1
Medication: Lisinopril	0.1	0.2	0.3	0.3	0.6	0.2
Vascular/heart problems diagnosed by doctor	0.1	0.2	0.6	-0.2	0.1	0.7
Bipolar Disorder or Schizophrenia	0.0	0.1	0.2	0.4	0.3	0.1
Depressed Affect (Nagel 2018)	0.0	0.1	0.1	0.4	0.2	0.3
Intelligence (Savage-Jansen 2018)	0.0	0.1	0.2	-0.0	0.2	-0.4
HbA1C	0.0	0.1	0.1	-0.3	-0.2	-0.2
Heel bone mineral density (BMD) T-score, automated (left)	0.0	0.1	0.2	-0.1	-0.1	-0.4
Alcohol usually taken with meals	0.0	0.0	0.1	0.0	0.1	-0.3
Heel bone mineral density (BMD) T-score, automated (right)	0.0	0.1	0.2	0.4	-0.2	-0.2
Forced expiratory volume in 1-second (FEV1)	0.0	0.0	0.1	0.1	0.2	-0.1
Ever had stillbirth, spontaneous miscarriage or termination	0.0	0.0	0.1	0.1	-0.0	0.4

Hub : Genes

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Trait associations