Hub : Genes

PDLIM1

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Adipose Subcutaneous 0.1010 0.0360 0.00078 0.054 NA 0.019 NA 0.023 3.2e-05 NA 9.8e-03 NA 5.0e-03
2 GTEx Esophagus Muscularis 0.0840 0.0350 0.00730 0.080 NA 0.014 NA 0.055 1.4e-05 NA 4.4e-02 NA 2.8e-04
3 GTEx Nerve Tibial 0.0867 0.0373 0.00720 0.012 NA 0.009 NA 0.003 4.4e-02 NA 6.7e-02 NA 1.9e-01
4 GTEx Thyroid 0.0800 0.0360 0.00830 0.004 NA 0.001 NA 0.006 1.5e-01 NA 2.6e-01 NA 1.0e-01
5 METSIM Adipose 0.0629 0.0268 0.00063 0.005 0.014 0.020 0.018 0.014 4.8e-02 2.9e-03 4.1e-04 9.1e-04 2.5e-03
6 YFS Blood 0.1151 0.0285 0.00000 0.072 0.061 0.071 0.066 0.072 2.0e-22 2.6e-19 2.6e-22 1.1e-20 2.3e-22
7 TCGA Kidney Renal Clear Cell Carcinoma 0.0872 0.0378 0.00230 0.013 0.037 0.019 NA 0.019 1.1e-02 5.2e-05 2.8e-03 NA 3.1e-03
8 TCGA Prostate Adenocarcinoma 0.1014 0.0489 0.00850 -0.003 0.010 0.007 NA -0.002 8.9e-01 2.7e-02 5.1e-02 NA 6.0e-01
9 TCGA Uterine Corpus Endometrial Carcinoma 0.1970 0.0880 0.00760 0.165 0.098 0.157 NA 0.147 2.4e-05 1.1e-03 3.9e-05 NA 6.8e-05

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bipolar Disorder (2018) 0.4 0.7 1.9 -1.4 1.0 -0.6 -0.2 0.1 0.7 1.0 0.6 1.1
Bipolar Disorder or Schizophrenia 0.4 1.1 3.3 -1.8 -0.6 -1.1 1.1 0.1 -0.1 1.5 -1.1 -0.0
Depressed Affect (Nagel 2018) 0.7 1.4 5.7 0.4 -0.6 0.1 -0.7 1.3 2.4 0.3 1.7 -1.3
Depression (Nagel 2018) 1.0 1.5 4.8 1.0 -0.7 0.6 -1.6 0.9 1.7 0.5 -0.0 -2.2
Intelligence (Savage-Jansen 2018) 0.2 0.5 1.5 -0.2 -0.1 -0.7 -1.0 0.9 -0.4 -0.4 0.3 1.2
Neuroticism (Nagel 2018) 0.8 1.9 6.1 0.6 -0.8 0.7 -0.9 1.6 2.5 0.7 2.1 -1.0
Schizophrenia (2018) 0.7 1.5 3.5 -1.2 -1.6 -0.9 1.6 0.0 -0.7 1.0 -1.9 -0.9
Schizophrenia vs Biploar Disorder 1.9 2.6 9.9 1.3 -1.7 0.5 -0.3 -0.5 0.6 -2.8 -0.2 -3.1
Worry (Nagel 2018) 0.5 1.1 3.4 0.1 -0.6 0.9 -1.1 0.5 1.8 -0.0 1.2 -1.4
Alzheimer’s Disease (in mother) 0.9 1.1 3.2 -0.2 0.1 0.0 -0.4 1.8 1.6 1.2 1.5 0.1
Alzheimer’s Disease (in father) 0.6 0.7 1.9 0.3 1.2 0.4 0.5 -0.8 -0.7 -1.0 -1.4 0.4
Alzheimer’s Disease (including proxy) 0.3 0.5 1.7 0.4 1.3 0.7 0.1 0.5 0.7 -0.3 -0.1 1.0
Crohns Disease (2017) 0.3 0.6 4.1 0.1 -0.3 -0.6 0.1 0.5 0.2 0.4 2.0 -0.6
Irritable Bowel Disease (IBD) 0.4 0.9 2.6 1.3 -0.6 1.0 0.2 1.0 0.3 0.7 1.6 -0.8
Ulcerative Colitis (UC) 0.6 1.2 3.2 1.8 -0.8 1.7 0.3 1.5 0.5 0.5 0.5 -1.0
Major Depression (MDD) 0.5 0.6 1.5 1.1 0.5 0.9 -0.6 0.4 -0.1 0.2 -1.2 1.0
Reaction Time 0.8 1.5 7.1 0.8 1.1 0.5 -0.0 0.3 0.7 2.7 -1.9 0.3
Verbal and Numeric Reasoning (VNR) 0.4 1.0 3.7 -1.1 -0.6 -1.4 -0.6 -0.8 -1.0 -1.9 -0.2 0.3
Breast Cancer 1.2 2.9 6.3 2.5 -0.5 2.1 -2.4 1.2 2.1 -0.7 -0.2 -1.9
Ovarian Cancer 0.4 0.5 1.2 -1.0 0.1 -1.1 -1.0 0.5 0.8 -0.5 0.3 0.1
Prostate Cancer 0.7 0.9 7.1 0.0 -0.3 0.2 -0.5 0.6 0.6 0.4 -2.7 -0.2
Age at First Birth 0.5 0.7 1.7 0.4 -0.0 1.2 0.8 1.3 -0.5 0.2 0.8 -1.3
Bipolar Disorder (2011) 0.7 0.7 4.5 -0.4 0.9 -0.1 0.2 -0.2 0.2 2.1 -0.2 1.0
Body Mass Index (BMI) (2010) 0.6 0.8 2.0 -0.5 0.0 -1.1 1.4 -0.2 -0.8 0.4 1.2 1.2
Coronary Artery Disease (CAD) 0.3 0.4 1.3 0.7 -0.6 0.6 -0.1 0.7 -0.4 0.4 -1.1 -0.5
Crohns Disease (2012) 0.6 0.9 2.2 -0.7 -0.7 -0.8 1.4 -0.1 -1.5 0.6 1.3 0.5
Mean Putamen Volume 0.6 0.7 2.7 -0.1 -1.6 -0.2 -0.3 -1.2 -0.9 -0.7 -0.2 -0.6
Fasting Glucose 2.0 2.4 7.7 -1.7 0.2 -2.8 -0.8 -1.8 -0.3 -1.0 -2.4 0.5
HbA1C 0.5 0.5 1.3 -0.7 0.8 -0.9 -0.8 1.1 0.8 0.4 -0.0 0.1
HDL Cholesterol 0.2 0.4 1.5 0.3 0.4 0.6 1.2 -0.6 -0.1 -1.1 -0.3 0.2
LDL Cholesterol 0.6 0.9 2.7 -0.4 0.4 -0.6 1.7 -0.2 -1.5 -0.5 1.0 1.1
Lupus 0.4 0.7 2.9 -0.2 -1.7 0.1 0.1 -0.5 -0.1 0.4 -0.6 -1.5
Neuroticism (2016) 1.6 2.4 6.6 2.2 1.2 1.7 0.1 2.6 1.6 1.4 0.9 0.7
Primary Biliary Cirrhosis 0.6 0.8 1.7 -0.6 -0.5 -1.3 1.2 -1.1 -0.6 0.3 -1.1 0.6
Rheumatoid Arthritis 0.5 0.7 2.0 -1.4 0.2 -0.7 0.4 -1.0 0.2 0.8 -0.4 -1.4
Schizophrenia (2014) 0.5 1.1 3.7 -1.1 -0.5 -0.8 1.9 0.3 -1.1 0.4 -1.6 -0.1
Triglycerides 0.2 0.3 1.3 0.5 1.1 0.3 0.8 0.4 0.8 -0.2 0.2 -0.2
Type 2 Diabetes (T2D) (2012) 0.5 0.6 1.7 -0.2 0.4 -0.4 -0.4 -0.8 0.8 -1.3 1.2 -0.7
Ulcerative Colitis 0.1 0.2 0.4 0.5 -0.4 0.4 -0.0 -0.0 0.1 0.6 0.6 -0.5
Blood Eosinophil Count 0.3 2.3 6.1 0.6 -2.5 0.9 -1.5 1.9 1.2 2.1 0.6 -1.2
Blood Platelet Count 0.4 5.0 14.4 0.8 -0.7 1.2 0.7 3.8 2.4 2.3 2.8 -3.0
Blood Red Count 0.7 6.3 21.9 -2.3 -1.9 -1.7 -0.3 2.8 4.7 1.7 1.8 -3.0
Blood White Count 1.9 14.2 36.4 -4.9 -2.8 -3.5 -2.2 3.8 6.0 0.4 2.4 -4.7
Heel T-Score 0.4 2.9 10.8 3.3 1.5 2.6 -1.0 -0.0 -0.6 -0.8 1.9 0.6
BMI 0.2 1.0 4.5 -0.1 0.7 -1.1 -0.1 0.7 0.8 2.1 1.2 0.4
Height 0.2 3.7 10.8 -1.5 -2.7 -0.4 0.6 -3.2 -0.6 -3.3 -0.6 -1.2
Waist Hip Ratio (WHR) 0.7 3.4 10.7 -1.1 0.2 -0.5 -1.3 -0.9 2.2 -3.3 0.8 -3.2
Systolic Blood Pressure 0.6 3.1 7.6 -2.4 0.7 -2.2 -1.2 -1.4 2.8 1.3 1.1 -1.7
Smoking Status 0.2 0.5 3.4 -0.1 -0.4 0.1 -0.1 -0.6 0.1 -0.1 -1.8 -0.6
Allergy or Eczema 0.6 1.7 3.8 1.9 0.7 1.6 0.6 0.5 -0.9 -0.3 -1.9 1.7
Cardiovascular Disease 0.7 2.3 6.2 -1.6 0.1 -2.0 -2.5 -1.5 1.1 1.3 1.2 -1.0
Hypothyroidism (self reported) 0.2 0.5 2.8 -0.1 0.3 -0.4 0.3 -0.0 -1.1 0.1 -0.1 1.7
Respiratory disease 0.8 1.7 3.1 1.8 -1.5 1.1 -1.6 1.6 0.7 0.2 -1.2 -1.2
Type 2 Diabetes (T2D) (2018) 0.2 0.4 1.6 -0.4 0.4 -0.6 -0.7 -0.5 1.3 0.1 0.4 -0.4
Lung FEV1/FVC ratio 0.7 3.6 14.4 -1.7 0.9 -1.0 0.7 -3.8 -3.0 -1.6 -1.0 -0.8
Lung FVC 0.3 1.4 3.0 -1.7 0.6 -1.3 -1.6 0.6 1.0 0.6 1.7 -0.8
Neuroticism 1.8 4.3 13.7 1.0 -0.8 1.2 -2.7 2.5 3.7 2.0 1.2 -1.7
Chronotype (morning person) 0.5 1.2 4.6 0.2 1.6 0.1 -0.1 -0.2 1.8 -2.1 -0.4 -0.4
Hair Pigment 0.0 0.8 3.9 -0.1 1.1 -0.2 -0.3 0.4 0.8 0.8 0.6 2.0
Tanning 0.1 1.0 2.9 -1.2 0.4 -0.7 -0.0 -1.3 -0.5 -1.7 -1.6 0.3
Hand grip strength (left) 1.3 3.4 6.6 1.9 0.9 2.5 2.3 0.8 -1.4 1.7 1.4 2.6
Number of treatments/medications taken 0.4 0.7 1.9 -0.6 0.1 -1.3 -1.4 -1.0 0.3 -0.4 -0.8 -0.7
Average weekly spirits intake 0.7 0.8 3.6 -0.3 1.5 -0.4 -0.0 0.4 -0.5 0.2 1.0 1.9
Sensitivity / hurt feelings 0.7 1.1 2.1 1.2 1.2 0.5 -0.2 1.1 1.1 1.5 0.6 1.5
Frequency of depressed mood in last 2 weeks 0.3 0.5 0.9 -0.1 -0.7 -0.5 -0.5 0.8 0.9 0.7 0.4 -1.0
Hearing difficulty/problems: Yes 2.2 3.4 14.1 -1.6 -0.2 -1.7 -3.8 -0.4 2.3 0.1 -1.1 -2.1
Relative age of first facial hair 0.2 0.4 1.1 -0.0 1.1 0.8 -0.2 -0.5 0.2 -0.8 -0.8 -0.5
Other serious medical condition/disability diagnosed by doctor 0.9 1.2 6.0 -1.5 1.1 -2.5 0.1 -0.7 -0.0 -0.5 0.3 -0.1
Ever used hormone-replacement therapy (HRT) 0.4 0.5 2.5 -0.1 -0.4 -0.5 -0.7 0.6 1.6 0.1 -0.3 -0.5
Ever had hysterectomy (womb removed) 0.5 0.6 2.2 -0.3 -0.9 -0.9 -0.5 -0.0 0.8 1.5 -0.3 -0.6
Systolic blood pressure, automated reading 0.8 2.2 8.9 -1.1 2.0 -1.4 0.1 -1.0 3.0 0.6 1.2 -0.9
Eye problems/disorders: Diabetes related eye disease 0.7 0.7 2.3 -0.6 -0.6 -0.7 -1.1 -0.5 0.6 0.2 1.5 -1.1
Angina 1.1 1.5 5.9 0.9 -0.7 0.9 -2.2 0.6 0.3 0.0 0.3 -2.4
Medication for hormone replacement therapy 1.3 1.4 2.9 1.5 -1.7 1.5 -0.3 0.5 0.3 -0.8 -1.1 -1.6
Vitamin and mineral supplements 0.2 0.3 1.2 -0.3 -0.0 -1.1 -0.7 -0.2 0.2 0.8 -0.2 -0.1
Supplements: Zinc 1.1 1.2 2.8 1.5 0.1 1.7 -0.4 1.7 1.2 0.7 -0.8 -0.1
Medication: Co-codamol 0.7 0.8 3.3 -0.1 0.3 -0.9 -0.5 0.5 -1.0 0.5 1.8 0.9
Medication: Metformin 1.1 1.6 6.4 0.7 0.6 0.5 -1.3 0.8 2.5 1.2 0.6 -1.6
Diabetes (father) 1.1 1.3 2.8 -1.3 -1.0 -1.7 -0.2 -1.1 -0.8 -1.0 1.4 -1.2
Diabetes (mother) 0.3 0.4 1.9 -0.0 -0.1 0.3 -0.2 0.1 -1.4 0.4 1.1 -0.3
Severe depression (siblings) 0.9 1.0 4.4 -2.1 -0.3 -1.6 0.7 -0.5 -0.8 -0.1 -0.6 -0.2
Pack years adult smoking proportion 1.5 2.3 7.6 -2.5 -0.5 -2.8 -0.1 -1.2 0.7 -1.9 0.5 -1.2
Impedance of leg (right) 0.8 3.7 10.9 -2.9 -3.3 -1.9 0.9 -1.2 -0.2 -2.0 -0.2 -2.1
Leg fat-free mass (left) 0.2 1.0 2.6 1.4 1.6 1.1 0.6 0.2 0.2 0.4 1.4 0.6
Trunk fat percentage 0.3 1.3 3.0 -1.4 -0.3 -1.5 -0.4 0.5 1.7 1.4 0.6 -1.5
Hand grip strength (right) 1.2 3.3 13.0 0.0 1.0 0.9 3.6 0.4 -1.8 1.0 1.9 2.5
Townsend deprivation index at recruitment 0.8 1.2 4.0 -0.3 -1.0 -0.2 -1.3 0.1 1.6 -0.1 -1.1 -2.0
Current tobacco smoking 0.9 1.5 6.2 -0.8 0.7 -0.7 2.5 -0.6 -1.9 -0.4 -0.0 1.1
Average weekly fortified wine intake 0.7 0.8 2.4 -0.9 1.0 -1.1 0.0 -1.5 0.4 -1.2 -0.1 -0.1
Maternal smoking around birth 0.9 1.3 3.0 1.4 -1.7 0.2 -0.7 1.7 0.9 1.0 -1.3 0.1
Fed-up feelings 0.3 0.5 1.5 0.3 -0.5 -0.4 -0.8 0.6 1.2 1.0 0.2 -0.9
Frequency of unenthusiasm / disinterest in last 2 weeks 1.4 1.9 3.9 0.4 -1.9 0.2 -1.3 1.5 1.5 1.7 0.0 -2.0
Relative age voice broke 0.3 0.4 1.5 -0.1 -1.0 0.3 1.2 -0.0 -1.0 0.1 -0.4 -0.4
Taking other prescription medications 0.4 0.7 2.6 -0.0 0.1 -0.4 -1.3 -1.0 0.4 -0.8 -1.6 0.2
Age when periods started (menarche) 0.3 0.8 6.2 -0.2 -0.3 -0.3 -2.5 -0.7 0.4 -0.1 -0.5 -0.1
Bilateral oophorectomy (both ovaries removed) 0.7 0.8 2.7 0.4 -1.2 0.7 -0.4 1.2 0.8 1.6 -0.4 -0.5
Heel bone mineral density (BMD) T-score, automated (left) 0.6 1.3 4.7 1.5 0.7 0.7 0.9 -0.3 -2.2 0.2 0.0 1.6
Tinnitus: Yes, but not now, but have in the past 0.1 0.1 0.4 0.5 0.3 0.4 -0.6 -0.1 -0.3 0.3 0.1 0.5
Qualifications: CSEs or equivalent 0.6 0.8 2.1 1.1 -1.4 0.8 0.2 0.5 -0.8 1.1 -1.1 0.6
Serious illness, injury or assault to yourself 0.4 0.5 1.6 -1.3 -0.0 -1.0 0.6 -0.7 0.3 0.5 -0.7 -0.4
High blood pressure 1.0 2.7 6.7 -1.7 0.8 -2.6 -1.6 -1.7 1.6 0.1 2.0 -1.5
Hayfever, allergic rhinitis or eczema 0.3 0.6 2.8 0.3 -0.3 0.2 0.6 -0.3 -0.9 -0.6 -1.7 1.1
Multivitamins +/- minerals 0.8 1.0 2.9 0.8 0.6 1.7 0.5 1.5 -0.6 -0.2 1.4 0.6
Stomach or abdominal pain in last month 0.6 0.8 3.7 0.3 0.0 0.7 0.0 0.4 1.3 -1.9 -0.7 -0.7
Supplements: Glucosamine 0.4 0.5 2.0 0.1 0.8 -0.1 0.8 -0.1 -0.3 0.9 0.1 1.4
Diverticular disease/diverticulitis (self-reported) 0.7 0.8 2.0 1.4 -0.7 1.2 -1.1 0.5 -0.7 -1.0 -0.4 -0.1
Medication: Atenolol 1.0 1.2 5.5 -0.8 -0.3 -0.7 -0.6 0.0 1.7 -0.8 -0.5 -2.3
Medication: Levothyroxine sodium 0.6 1.0 2.4 1.5 1.3 1.2 -1.4 -0.9 0.4 -0.7 -0.6 0.2
Sitting height 0.2 1.5 5.8 1.0 0.3 1.4 0.3 -1.7 -0.4 -2.4 -0.9 1.0
Chronic bronchitis/emphysema (father) 1.8 2.1 5.6 0.9 0.5 0.6 -2.3 -0.6 1.8 -0.2 -2.4 -1.6
High blood pressure (mother) 1.2 1.7 5.1 -1.8 1.7 -1.3 -0.1 0.3 0.5 0.9 2.3 0.8
Body mass index (BMI) 0.3 1.3 3.8 0.5 1.3 -0.4 -0.4 0.9 1.9 1.9 0.9 -0.8
Impedance of leg (left) 0.7 3.5 9.2 -2.9 -3.0 -1.9 0.7 -1.0 0.5 -1.9 -0.4 -2.3
Leg predicted mass (left) 0.2 1.0 2.4 1.5 1.6 1.1 0.6 0.3 0.2 0.5 1.3 0.6
Trunk fat mass 0.2 1.1 3.5 -0.9 0.1 -1.0 -0.2 0.3 1.9 0.8 0.9 -1.6
Waist circumference 0.5 1.7 6.9 -0.1 0.8 -0.7 -1.0 0.8 2.6 0.2 1.4 -1.9
Number of incorrect matches in round 1.4 2.3 7.3 2.1 -0.4 2.7 -2.2 1.7 0.9 0.6 -0.2 -0.0
Past tobacco smoking 0.9 1.6 8.6 0.9 1.4 0.4 1.4 0.3 0.2 -1.1 2.9 0.3
Alcohol usually taken with meals 0.4 0.6 1.6 -1.2 0.9 0.2 0.1 0.5 0.7 -0.7 1.1 -1.0
Nervous feelings 0.9 1.6 3.7 1.1 -1.9 1.7 -0.8 1.5 1.0 1.3 0.7 -0.7
Frequency of tenseness / restlessness in last 2 weeks 0.6 1.0 2.8 -0.7 -0.1 -0.6 -0.7 0.9 1.7 0.1 1.1 -1.5
Hearing difficulty/problems with background noise 0.9 1.5 5.7 -1.9 0.0 -2.4 -0.3 -0.9 0.9 0.9 -1.1 -0.5
Hair/balding pattern: Pattern 2 0.9 1.2 3.9 0.2 -1.4 0.5 -0.9 0.7 1.4 -0.3 -0.9 -2.0
Had menopause 0.6 0.8 3.8 0.2 -0.9 0.1 -0.4 0.0 1.1 1.9 -0.6 -0.6
Had other major operations 0.2 0.2 0.7 0.1 0.1 0.1 0.2 -0.4 0.6 -0.6 -0.8 -0.7
Forced vital capacity (FVC) 0.4 1.5 4.3 -2.0 -0.3 -1.3 0.4 -0.8 0.4 -0.8 2.1 -1.1
Heel bone mineral density (BMD) T-score, automated (right) 0.4 1.0 5.0 -0.0 0.3 -0.0 1.4 0.0 -2.2 0.5 1.1 0.9
Ever unenthusiastic/disinterested for a whole week 1.8 2.3 5.2 0.9 -0.4 1.2 -2.3 0.7 2.2 2.0 -0.8 -1.7
Qualifications: None of the above 0.5 1.1 3.3 1.1 1.3 0.0 -1.8 -0.5 0.8 1.4 -0.3 -0.4
Financial difficulties in last 2 years 0.7 1.0 5.7 -0.2 -0.6 -0.2 -0.9 -0.2 0.8 2.4 -0.8 -0.9
Mouth/teeth dental problems 1.2 1.9 6.2 -1.8 -2.5 -1.3 0.4 -0.9 -1.6 0.0 0.0 -1.3
Heart attack 0.9 1.2 4.7 -0.6 1.0 -0.8 -2.2 0.8 1.2 0.6 -1.1 0.3
Allergy 0.2 0.6 1.3 -0.8 1.0 -0.8 -0.1 -0.4 0.9 0.6 1.2 -0.5
Pain all over the body in last month 1.0 1.1 3.2 -1.2 -0.5 -1.2 0.7 -1.2 -1.0 -0.6 1.8 0.0
Diabetes (self-reported) 1.0 1.5 3.1 -1.1 -0.1 -1.4 -1.7 -1.1 1.8 0.5 0.6 -1.6
Hayfever/allergic rhinitis (self-reported) 0.8 1.0 5.7 -0.3 1.1 -0.2 0.2 0.7 -1.0 0.1 -0.7 2.4
Medication: Ramipril 1.4 1.8 4.2 -0.3 -2.0 -0.2 -2.0 -1.3 -0.7 1.4 -0.2 -2.0
Medication: Simvastatin 1.4 2.1 9.9 -0.1 -1.8 -0.2 -3.1 0.6 1.1 1.5 0.7 -1.3
Fluid intelligence score 0.8 1.8 5.3 -2.1 -0.6 -2.1 0.0 -0.2 -0.5 -2.3 -0.9 0.2
Illnesses of siblings 2.8 4.0 19.4 0.6 -4.4 1.3 -1.1 2.1 0.4 2.6 0.3 -1.1
Neuroticism score 0.7 1.5 3.7 0.5 -0.3 0.3 -1.7 1.2 1.9 1.7 1.2 -0.7
Weight 0.2 0.8 3.2 0.5 1.0 0.1 0.2 0.3 1.8 0.5 1.2 -0.9
Impedance of arm (right) 0.4 2.0 5.6 -2.4 -2.3 -1.1 0.0 -1.2 -1.6 -0.8 -0.9 -0.2
Arm fat percentage (right) 0.2 0.8 2.8 -0.6 0.7 -0.9 -0.3 0.3 1.2 1.7 0.3 -0.9
Trunk fat-free mass 0.2 1.3 3.2 1.7 1.4 1.4 0.6 -0.0 0.8 -0.8 1.8 -0.2
Hip circumference 0.1 0.6 3.3 0.3 0.5 -0.2 0.4 0.3 1.8 0.6 0.4 -0.7
Time employed in main current job 1.1 1.3 3.1 1.0 -1.0 1.3 1.7 0.5 -1.7 1.0 0.3 -0.7
Alcohol intake versus 10 years previously 0.4 0.7 1.6 1.2 0.5 -0.2 0.5 -0.8 -1.3 -0.4 -1.0 0.8
Father’s age at death 1.3 1.7 4.5 -2.1 0.8 -1.6 -0.9 -1.2 0.4 -2.0 -1.1 0.5
Worrier / anxious feelings 0.5 1.0 2.3 -0.9 -0.9 -0.8 -0.8 -0.6 1.4 -0.1 1.2 -1.5
Frequency of tiredness / lethargy in last 2 weeks 1.0 1.5 3.9 -0.4 -1.7 0.3 -0.7 1.3 0.8 0.5 2.0 -1.9
Falls in the last year 0.5 0.7 2.5 -0.5 0.6 -0.4 1.6 -1.0 -1.0 -0.1 0.8 0.7
Hair/balding pattern: Pattern 3 0.7 1.1 4.2 -0.0 0.9 -1.1 0.2 0.0 -0.7 1.6 2.0 0.6
Number of live births 0.8 1.1 4.6 -0.3 0.5 0.1 -0.1 1.5 2.1 1.4 0.2 -1.0
Forced expiratory volume in 1-second (FEV1) 0.4 1.2 3.0 -1.7 -0.5 -0.9 0.4 -1.3 -0.4 -0.8 1.7 -1.0
Pulse rate 0.8 1.4 3.4 1.8 1.5 0.3 0.9 -1.5 -0.5 -1.6 -0.5 0.9
Happiness 0.2 0.2 0.8 0.4 0.5 0.6 0.1 0.5 0.9 0.2 0.6 -0.2
Noisy workplace 0.9 1.2 2.9 -0.7 -1.7 -0.6 -1.2 -0.8 -0.9 0.7 0.7 -1.7
Qualifications: A levels/AS levels or equivalent 0.6 1.3 4.7 -1.5 -0.5 -1.0 0.4 -0.9 -0.6 -0.0 -1.3 2.2
Serious illness, injury or assault of a close relative in last 2 years 1.4 1.7 6.7 0.5 -1.7 0.4 -2.6 0.0 1.2 0.3 -1.5 -1.1
Mouth/teeth dental problems: Dentures 1.5 2.5 9.3 1.8 1.4 0.9 -2.4 0.7 3.0 0.2 -0.7 -0.6
Asthma 0.7 1.4 3.7 1.1 -1.1 0.9 -1.7 1.9 0.9 0.3 -1.3 -0.5
Medication: Ibuprofen (e.g. Nurofen) 1.6 2.0 4.1 0.7 -0.6 1.1 1.8 2.0 -1.2 1.3 1.8 1.5
Medication: Cholesterol lowering 1.4 2.1 16.4 0.1 -0.7 0.2 -4.1 -0.8 -0.1 0.9 -0.1 -0.8
Depression (self-reported) 0.8 0.9 2.5 -1.0 1.0 -0.8 -0.3 1.4 1.6 -0.6 -0.5 0.3
Medication: Lansoprazole 0.4 0.5 2.4 -0.4 0.0 -0.6 -0.2 0.0 0.2 1.0 -1.5 0.4
Prospective memory result 0.9 1.1 4.1 -0.1 0.5 0.3 1.6 -1.0 -2.0 0.6 1.1 0.6
Lung cancer (father) 0.8 0.9 2.8 0.5 0.0 0.4 -1.1 1.5 1.7 0.2 -0.0 -1.1
Illnesses of mother 1.6 1.9 4.4 2.1 -0.9 2.1 1.6 0.8 -1.5 -0.2 -1.0 1.3
Forced expiratory volume in 1-second (FEV1), Best measure 0.7 2.4 5.6 -2.0 -1.5 -1.2 0.6 -2.4 -1.5 -0.6 1.4 -1.8
Pulse wave Arterial Stiffness index 1.5 1.8 8.2 1.3 0.9 1.2 0.2 1.5 2.9 -0.6 -0.2 -1.2
Impedance of arm (left) 0.4 2.0 6.3 -2.5 -2.2 -1.3 0.3 -0.8 -1.5 -0.7 -1.3 0.1
Arm fat mass (right) 0.2 0.8 1.8 -0.3 0.9 -0.6 0.2 0.4 1.3 1.4 1.2 -0.9
Trunk predicted mass 0.2 1.3 3.3 1.7 1.3 1.4 0.6 0.1 0.9 -0.8 1.8 -0.2
Standing height 0.2 2.1 10.6 -0.1 -0.3 0.8 1.5 -1.8 -0.2 -3.3 1.1 -0.5
Length of working week for main job 1.9 2.1 5.1 -0.9 0.7 -1.5 1.0 -1.3 -2.2 1.9 -0.5 2.0
Exposure to tobacco smoke at home 1.0 1.1 3.2 0.7 -0.7 0.7 -1.8 0.8 1.6 -0.3 -1.2 -0.8
Breastfed as a baby 0.2 0.3 1.1 -0.4 0.1 0.1 0.8 -0.8 -1.0 0.5 0.1 -0.3
Tense / ‘highly strung’ 0.5 0.8 2.7 -0.2 -0.0 0.1 -1.5 0.3 1.7 -0.7 0.3 -1.3
Seen doctor (GP) for nerves, anxiety, tension or depression 0.2 0.3 0.7 -0.6 -0.5 -0.2 -0.1 0.7 0.6 -0.1 -0.6 -0.8
Hair/balding pattern: Pattern 4 0.6 1.3 3.7 1.8 1.1 1.9 -0.3 0.7 -0.3 0.5 -0.4 1.7
Birth weight of first child 1.7 3.0 7.8 -1.2 -2.8 -1.1 1.5 -1.4 -1.9 0.7 1.8 -2.3
Peak expiratory flow (PEF) 0.3 0.6 2.6 -1.6 0.2 -0.7 1.0 0.2 -0.5 -0.8 0.3 0.3
Pulse wave reflection index 0.9 1.2 4.2 -0.3 1.0 0.5 1.3 2.0 1.5 -0.0 1.0 -0.3
Ever highly irritable/argumentative for 2 days 0.5 0.6 1.6 0.9 0.3 0.9 -1.3 0.1 0.7 1.0 -0.2 -0.6
Loud music exposure frequency 0.6 0.6 1.5 -1.2 -0.2 -0.8 -0.9 -0.9 0.6 0.4 -0.2 -1.1
Qualifications: O levels/GCSEs or equivalent 0.6 1.0 2.2 -0.3 -1.5 0.1 0.8 -0.8 -1.5 -1.1 -1.3 0.8
Mouth/teeth dental problems: Bleeding gums 1.1 1.4 5.8 0.4 1.7 0.8 1.2 0.0 -0.7 0.3 -1.2 2.4
Blood clot in the leg (DVT) 0.8 1.1 4.2 1.1 0.6 1.1 1.1 -0.5 -2.0 0.2 0.4 0.9
Medication: Paracetamol 0.9 1.5 3.6 -1.2 0.2 -1.9 1.5 -0.3 1.0 0.2 1.2 -1.9
Headache pain in last month 0.6 1.0 5.6 -1.0 -0.6 -0.3 2.4 1.1 -0.3 0.6 0.7 0.4
Medication for cholesterol, blood pressure or diabetes 1.3 2.2 11.8 1.4 0.1 1.2 3.4 0.6 -1.0 -0.4 -0.9 1.5
Glaucoma (self-reported) 0.7 0.8 2.8 1.0 0.3 1.2 -0.6 0.7 1.7 -0.4 -0.3 -1.0
Gout (self-reported) 0.8 1.1 3.4 0.6 0.4 0.4 0.1 -1.4 -1.7 -1.9 -0.1 -0.7
Hypothyroidism/myxoedema (self-reported) 0.2 0.4 1.4 0.7 1.1 0.4 -0.7 -0.1 -0.3 -0.2 -0.3 1.2
Medication: Amlodipine 0.7 1.0 2.0 -1.4 -0.6 -1.4 -1.3 0.5 0.9 1.2 0.7 0.6
Medication: Ventolin 100micrograms inhaler 1.1 1.4 3.1 -0.3 -1.6 -0.2 -1.8 1.2 0.8 -0.4 -1.5 -1.4
Birth weight 0.7 1.6 4.3 0.4 0.2 0.9 1.4 -1.3 -2.1 1.1 0.2 2.0
Chronic bronchitis/emphysema (mother) 1.2 1.4 6.0 1.3 -2.4 0.4 -0.4 0.5 0.2 -0.7 -1.2 -1.4
High blood pressure (siblings) 2.1 3.0 13.4 -1.4 3.7 -1.7 1.4 -2.1 -0.2 -1.2 -0.9 0.8
Forced vital capacity (FVC), Best measure 0.6 2.1 5.4 -2.3 -1.2 -1.5 0.5 -1.7 -0.8 -0.2 1.7 -1.6
Body fat percentage 0.4 1.6 3.8 -1.4 -0.3 -1.6 -0.4 0.6 2.0 1.4 0.6 -1.8
Leg fat percentage (right) 0.5 1.9 5.8 -1.1 -0.3 -1.6 -0.1 0.5 2.2 1.3 1.0 -2.4
Arm fat-free mass (right) 0.3 1.5 3.3 1.6 1.3 1.2 0.9 0.8 1.8 -0.0 1.8 -0.3
Exposure to tobacco smoke outside home 1.3 1.7 6.1 0.4 -0.1 0.1 -1.2 1.5 2.0 2.5 -1.0 -0.7
Comparative body size at age 10 0.2 0.7 1.5 1.2 0.4 -0.1 -1.0 -0.4 -0.8 1.1 -0.7 0.9
Number of full brothers 1.6 2.0 7.0 -2.6 -0.3 -2.4 0.5 0.3 1.2 1.0 -1.0 -1.2
Worry too long after embarrassment 1.4 2.4 8.9 0.7 -0.1 0.7 0.3 3.0 2.2 1.9 1.5 0.7
Seen a psychiatrist for nerves, anxiety, tension or depression 0.6 0.8 2.3 0.7 -0.7 0.5 -1.4 0.9 1.5 0.6 -1.0 -0.4
Wheeze or whistling in the chest in last year 1.2 2.1 5.1 2.2 -1.1 1.8 -1.8 0.8 0.9 -0.2 -1.3 -1.8
Number of children fathered 1.7 1.9 6.1 0.9 2.5 0.2 1.2 -1.5 0.1 -1.9 1.7 0.2
Reason for reducing amount of alcohol drunk: Health precaution 0.5 0.5 1.8 0.5 1.2 0.8 0.7 0.2 -0.4 0.2 1.3 0.1
Age at first live birth 0.8 1.3 5.4 0.8 -2.3 1.5 -0.2 1.2 -0.2 -0.7 -1.0 -0.8
Pulse wave peak to peak time 1.6 1.9 8.2 -1.4 -0.9 -1.2 -0.2 -1.6 -2.9 0.3 0.3 1.2
Health satisfaction 0.3 0.4 2.5 -0.1 0.2 -0.3 1.6 -0.2 -0.7 0.1 0.8 0.1
Shortness of breath walking on level ground 1.0 1.2 4.2 -0.4 1.7 -1.1 0.0 -2.1 -0.8 -0.4 0.6 0.9
Qualifications: College or University degree 0.2 0.7 2.3 -0.5 -1.5 0.4 0.3 1.4 -0.0 -0.1 1.3 -0.2
Eye problems/disorders: None of the above 1.2 1.3 4.8 0.8 -1.1 1.1 0.3 1.2 -2.2 -0.2 1.4 1.0
Mouth/teeth dental problems: Loose teeth 1.3 1.6 5.3 0.9 0.5 0.4 -0.7 2.3 1.7 -0.3 1.6 -1.3
Emphysema/chronic bronchitis 0.6 0.6 2.3 0.9 -0.6 0.7 -1.5 0.4 0.5 -0.9 0.5 -0.6
Medication for pain relief, constipation, heartburn 0.4 0.7 2.4 0.7 0.5 1.1 -0.9 -0.1 -0.9 0.2 -0.0 1.6
Neck or shoulder pain in last month 0.6 0.8 2.3 1.1 0.8 1.0 -0.8 1.5 1.0 0.7 0.4 0.5
Medication: Blood pressure 1.3 2.3 9.3 -0.9 -0.9 -0.8 -3.1 -0.5 1.3 -0.0 1.2 -2.3
Angina (self-reported) 1.2 1.5 6.4 0.7 -0.7 0.6 -2.4 0.4 0.4 -0.0 0.1 -2.5
Migraine (self-reported) 1.9 2.4 7.7 -1.4 -2.8 -1.7 -1.2 1.4 1.1 1.1 0.9 -1.5
Medication: Ibuprofen 1.4 1.7 4.2 1.7 -0.5 1.7 1.1 2.0 -1.1 0.9 0.9 1.1
Medication: Allopurinol 1.1 1.5 4.1 0.1 -1.4 -0.1 -0.7 -1.5 -1.6 -1.2 -2.0 -0.6
Medication: Omeprazole 0.9 1.0 2.0 1.3 -0.1 1.2 -0.4 0.8 1.1 -1.4 0.5 -1.3
Medication: Seretide 50 evohaler 0.5 0.5 2.4 -0.4 -0.7 0.1 -1.2 1.6 -0.0 -0.2 -0.2 0.4
Mean time to correctly identify matches 1.0 1.8 6.0 0.7 1.3 0.5 -1.2 0.6 1.1 2.5 -2.2 0.6
Heart disease (mother) 1.1 1.3 3.7 0.1 0.7 -0.0 -1.9 -1.4 1.5 0.1 -1.3 -1.2
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.9 1.1 4.8 0.2 -0.8 0.2 -2.2 -0.7 0.8 -0.3 -1.5 -0.7
Whole body fat mass 0.3 1.2 3.6 -0.9 0.2 -1.1 -0.2 0.5 1.9 1.0 1.1 -1.5
Leg fat mass (right) 0.3 1.3 4.5 -0.4 0.1 -1.0 -0.2 0.4 2.0 1.0 1.1 -2.1
Arm predicted mass (right) 0.3 1.5 3.7 1.6 1.2 1.2 0.8 0.8 1.9 -0.1 1.8 -0.4
Pulse rate, automated reading 0.2 0.6 1.8 1.2 0.6 -0.4 -1.1 -1.3 0.5 -0.4 -0.6 -0.2
Alcohol intake frequency. 0.5 1.1 3.1 -0.5 0.1 -1.2 -1.3 -0.3 1.0 -0.2 1.8 -1.5
Comparative height size at age 10 0.1 0.8 4.8 -0.1 0.3 0.6 0.3 -0.6 0.2 -2.2 1.1 -0.7
Number of full sisters 1.1 1.3 2.3 -1.1 1.4 -1.0 1.3 -0.2 -1.5 0.8 0.6 1.5
Suffer from ‘nerves’ 0.6 0.9 2.2 1.2 -0.3 1.5 -0.9 1.2 1.2 -0.0 0.1 -0.6
Overall health rating 0.5 1.1 3.0 0.5 -0.7 -0.0 -0.9 1.7 1.5 1.6 0.3 -0.7
Chest pain or discomfort 1.1 1.6 3.6 1.2 -0.9 0.8 -1.2 1.2 1.5 0.5 -1.5 -1.9
Had major operations 0.9 1.0 2.4 0.6 -1.3 0.0 -1.2 -0.4 0.5 -1.0 -1.2 -1.6
Age at last live birth 1.5 2.2 7.4 1.9 -1.2 2.1 -0.3 2.7 0.7 0.2 -1.4 -0.6
Family relationship satisfaction 0.8 1.0 3.2 -1.1 1.8 -0.9 1.2 0.2 1.4 -0.1 -0.2 0.1
Leg pain on walking 0.4 0.5 1.4 1.0 0.3 1.2 -0.5 0.8 0.8 0.6 -0.1 0.5
Qualifications: NVQ or HND or HNC or equivalent 0.7 0.8 3.4 0.2 -0.1 0.1 1.8 0.3 -1.2 0.0 -1.1 1.0
Commuting to job workplace: Car/motor vehicle 0.6 0.7 1.7 0.5 -0.0 0.7 1.0 0.3 -1.3 1.3 -0.8 0.9
Illness, injury, bereavement, stress in last 2 years 0.1 0.1 0.4 0.5 0.2 -0.2 0.2 0.4 -0.2 -0.7 -0.1 -0.0
Medication: Aspirin 1.0 1.3 4.2 -0.8 -0.3 -1.1 -2.0 0.1 1.2 0.8 -0.9 -1.8
Supplements: Vitamin C 0.4 0.4 1.8 0.1 1.3 0.3 0.6 -0.5 -0.7 0.5 -0.6 0.6
Knee pain experienced in last month 0.3 0.5 1.1 0.1 1.1 -0.5 -0.7 0.3 1.1 0.5 -0.9 -0.6
Hypertension (Self-reported) 1.0 2.7 6.7 -1.8 0.8 -2.6 -2.2 -1.8 1.6 -0.1 1.3 -1.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 1.2 1.3 3.8 -1.8 -0.2 -1.9 -0.8 -0.6 1.3 -1.3 -0.9 -0.4
Illnesses of father: Heart disease 0.3 0.4 2.2 0.1 -0.4 0.2 0.5 -0.9 -1.5 -0.1 0.2 0.5
Illnesses of siblings: Diabetes 2.0 2.4 9.4 1.8 3.1 1.1 -0.7 0.3 1.2 -2.2 1.1 -0.0
Smoking status: Previous 0.9 1.4 5.0 -0.0 -1.1 0.2 -1.7 0.5 1.1 1.1 -2.2 -0.8
Forced expiratory volume in 1-second (FEV1), predicted 0.5 1.1 3.4 -1.2 0.9 -0.9 1.8 -0.6 -0.2 -0.4 1.4 0.9
Whole body fat-free mass 0.2 1.3 3.0 1.7 1.6 1.4 0.7 0.3 0.7 -0.2 1.7 0.3
Leg fat-free mass (right) 0.2 1.3 3.3 1.8 1.7 1.4 0.4 0.5 0.5 0.5 1.3 0.7
Arm fat percentage (left) 0.2 0.9 3.7 -0.7 0.4 -1.0 -0.1 0.6 1.3 1.9 0.2 -0.8
Average weekly red wine intake 0.3 0.4 2.3 0.2 -0.1 0.4 0.4 0.3 0.4 -1.5 -0.1 -0.7
Handedness (chirality/laterality): Left-handed 0.1 0.1 0.4 0.0 -0.1 0.7 -0.2 -0.4 0.0 -0.2 0.5 0.4
Mood swings 0.4 0.7 2.6 0.5 -0.5 0.6 -0.7 1.3 1.6 -0.1 0.8 -0.0
Loneliness, isolation 1.3 1.7 4.6 -0.2 -1.1 -0.8 -0.8 1.7 1.4 0.9 2.1 -1.7
Long-standing illness, disability or infirmity 1.1 1.8 6.8 -1.7 -0.1 -2.6 -2.0 -0.6 0.5 0.4 -1.1 -0.6
Ever had bowel cancer screening 1.5 1.8 4.7 -1.6 0.1 -1.6 -2.2 1.4 2.0 0.8 -0.4 0.3
Diabetes diagnosed by doctor 1.2 1.9 4.4 -0.7 -1.0 -1.2 -2.0 -0.4 2.1 0.7 1.0 -2.0
Ever had stillbirth, spontaneous miscarriage or termination 0.6 0.6 1.2 -0.4 -1.0 -0.2 -0.8 0.0 0.7 -1.1 -1.1 -0.9
Friendships satisfaction 0.6 0.7 2.9 -0.2 0.9 -0.3 1.6 0.1 1.7 -0.6 -0.3 0.0
Qualifications: nursing, teaching 0.4 0.6 1.7 -0.4 -0.7 -0.6 1.2 0.1 -1.1 -1.3 0.2 -0.1
Commuting to job workplace: Walk 2.1 2.3 7.2 -2.0 0.9 -2.7 0.6 -1.3 0.5 -2.0 1.3 -0.2
Eye problems/disorders: Cataract 1.3 1.5 4.5 -1.4 0.4 -1.9 -0.4 0.2 2.1 1.2 1.1 -0.7
Mouth/teeth dental problems: Mouth ulcers 0.6 1.0 2.5 0.7 1.4 0.7 1.3 0.2 0.9 -0.7 1.6 -0.5
Medication for cholesterol 0.3 0.4 0.8 -0.6 0.9 -0.4 -0.0 0.7 0.6 0.4 -0.7 0.9
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.7 0.9 3.8 0.7 0.6 0.5 0.4 -1.2 0.6 -2.0 -0.5 -0.7
Back pain experienced in last month 1.2 1.7 6.1 0.9 2.5 0.4 -1.1 -0.2 0.9 -2.2 -1.1 -0.2
Mineral and other dietary supplements 0.4 0.5 1.6 0.1 -0.6 -0.0 -1.2 -0.1 -0.4 0.4 1.3 -0.7
Breast cancer (self-reported) 0.5 0.6 1.1 -1.0 0.3 -0.6 1.0 -0.7 -1.0 0.3 -0.4 0.9
Asthma (self-reported) 0.8 1.7 3.4 1.0 -1.5 0.9 -1.8 1.8 1.0 0.2 -1.5 -1.1
Osteoporosis (self-reported) 0.2 0.3 0.7 -0.8 -0.6 -0.3 0.5 0.5 0.5 0.4 0.7 -0.0
Osteoarthritis (self-reported) 1.2 1.6 6.0 0.1 -0.4 -0.3 -2.1 0.8 2.4 0.5 0.4 -1.7
Medication: Aspirin 1.1 1.4 4.4 -0.5 -0.4 -0.9 -2.1 0.7 1.3 1.0 -0.6 -1.8
Medication: Gliclazide 0.4 0.5 1.2 -0.9 -0.1 -1.1 -0.7 -0.2 0.3 0.8 -0.0 -0.9
Illnesses of father: None of the above (group 1) 0.8 1.0 5.4 0.3 -0.1 0.4 0.3 2.3 1.1 1.4 0.5 -0.1
Smoking status: Current 0.8 1.2 4.6 -1.1 0.5 -0.9 2.1 -0.8 -1.7 -0.3 -0.4 0.8
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.6 1.2 3.3 -1.8 -0.8 -1.4 -0.8 -0.8 0.8 -0.1 0.1 -1.6
Whole body water mass 0.2 1.4 3.2 1.8 1.7 1.4 0.7 0.4 0.8 -0.1 1.7 0.3
Leg predicted mass (right) 0.3 1.3 3.5 1.9 1.8 1.5 0.4 0.6 0.6 0.5 1.3 0.7
Arm fat mass (left) 0.2 0.9 2.2 -0.2 0.4 -0.7 0.2 0.5 1.5 1.5 1.0 -1.1
Number of self-reported non-cancer illnesses 0.8 1.3 4.0 -1.3 0.3 -2.0 -1.9 -0.9 0.7 -0.7 -0.0 -0.8
Average weekly champagne plus white wine intake 0.4 0.6 1.8 -0.7 0.2 -0.5 -0.0 0.4 0.7 -0.9 1.2 -1.3
Miserableness 0.5 0.8 2.6 0.5 -0.2 0.3 -0.1 1.1 1.6 1.6 0.4 -0.7
Guilty feelings 0.9 1.3 3.9 -0.1 -2.0 0.0 -0.8 0.8 1.6 1.6 -0.2 -1.4
Wears glasses or contact lenses 1.7 1.9 4.3 -0.4 -1.1 -1.6 -2.1 -1.5 0.8 -1.7 -0.6 -1.7
Ever taken oral contraceptive pill 0.6 0.7 1.3 -0.9 -0.6 -1.0 0.6 -1.1 -1.0 -0.9 0.0 0.2
Hearing aid user 1.1 1.2 3.8 -0.0 1.0 -0.6 0.1 -2.0 -1.1 -1.8 -0.9 0.6
Mother’s age at death 0.4 0.5 1.5 -0.6 0.2 -0.4 -1.1 -0.7 0.6 -1.2 -0.1 -0.5
Financial situation satisfaction 0.5 0.7 1.2 -1.1 -1.0 -0.8 -0.3 -0.9 -0.2 0.8 0.8 -0.8
Tinnitus: Yes, now most or all of the time 0.3 0.3 1.4 -0.1 -0.3 -0.1 -0.2 -0.1 0.6 -0.6 0.7 -1.2
Commuting to job workplace: Public transport 1.1 1.3 2.5 1.6 -0.4 1.3 -0.1 1.5 1.6 -1.0 -0.9 -0.7
Eye problems/disorders: Glaucoma 0.3 0.3 0.9 0.7 0.4 1.0 -0.3 0.0 0.4 -0.6 -0.4 -0.6
Medication: Blood pressure 0.2 0.4 2.0 0.1 0.6 -0.1 0.6 0.1 0.4 0.7 1.4 -0.0
Pain type(s) experienced in last month: Hip pain 0.4 0.5 3.0 0.0 1.7 -0.0 0.1 -0.2 0.1 -0.8 1.1 -0.2
Supplements: Fish oil (including cod liver oil) 0.5 0.7 2.6 -0.6 -0.4 -0.3 1.6 -0.3 -1.0 0.4 -0.3 1.4
High cholesterol (Self-reported) 1.1 1.9 12.0 -0.8 -1.1 -0.4 -3.5 -0.5 0.7 1.1 -0.3 -1.0
Medication: Bendroflumethiazide 0.5 0.7 3.1 -0.4 1.8 -0.8 0.2 0.0 -0.0 0.5 1.5 0.6
Medication: Paracetamol 0.9 1.4 4.8 -1.4 0.3 -2.2 1.2 -1.1 0.4 -0.4 0.7 -1.6
Medication: Lisinopril 0.2 0.3 1.6 -0.2 0.6 -0.6 -0.4 -0.2 0.3 0.3 1.3 0.5
Medication: Atorvastatin 0.6 0.7 3.2 -0.9 -0.1 -0.8 -1.1 0.3 -0.8 1.8 0.3 0.1
Illnesses of father: High blood pressure 0.9 1.1 2.5 -1.1 0.4 -1.0 1.6 -1.4 -1.4 -0.4 1.1 -0.2
Alcohol drinker status: Never 0.2 0.2 0.8 0.6 0.2 0.0 0.1 0.2 0.9 -0.0 0.1 -0.7
Ever smoked 0.6 1.0 3.5 -0.8 -1.5 -0.3 -0.8 -0.5 -0.9 0.6 -1.9 0.0
Basal metabolic rate 0.2 1.1 2.9 1.4 1.5 1.1 0.8 0.3 0.9 0.0 1.7 -0.0
Leg fat percentage (left) 0.6 2.0 6.4 -1.1 -0.3 -1.5 -0.4 0.4 2.4 1.3 0.8 -2.5
Arm fat-free mass (left) 0.3 1.5 5.2 1.2 1.3 0.9 0.7 0.5 1.8 -0.3 2.3 -0.8
Number of operations (self-reported) 0.6 0.9 4.4 0.4 -1.2 -0.2 -0.4 -0.1 0.6 -0.9 -0.4 -2.1
Average weekly beer plus cider intake 0.2 0.3 1.0 0.3 0.6 -0.4 0.7 -0.1 -0.0 0.7 1.0 -0.3
Irritability 0.2 0.3 1.3 0.5 0.0 -0.2 -1.1 -0.6 0.3 -0.5 0.3 -0.9
Risk taking 0.7 1.1 2.1 -1.4 1.3 -1.2 0.9 1.4 0.1 1.1 0.2 0.5
Ever had prostate specific antigen (PSA) test 0.7 0.8 2.0 1.1 1.3 1.3 -0.6 1.4 0.1 0.1 0.4 0.7
Fractured/broken bones in last 5 years 0.7 0.9 2.1 -1.3 0.3 -1.2 1.4 -0.0 0.7 -1.5 0.4 -0.0
Age started oral contraceptive pill 0.3 0.4 1.2 0.5 0.5 0.3 -1.0 -0.4 0.2 1.1 0.1 0.4
Diastolic blood pressure, automated reading 0.4 1.1 3.1 -0.6 0.8 -1.1 1.4 -0.6 1.3 0.6 1.8 -0.2
Ever depressed for a whole week 2.5 3.1 10.7 1.0 -0.2 0.8 -3.3 0.8 2.7 1.5 -2.1 -1.2
Unable to work because of sickness or disability 0.3 0.4 2.1 0.6 1.4 0.1 0.8 -0.1 -0.1 -0.4 -0.3 0.0
Commuting to job workplace: Cycle 1.0 1.2 2.8 -1.6 -0.6 -1.4 0.8 -1.7 -1.6 -0.2 0.5 0.3
Myopia 2.2 3.2 13.0 1.4 -1.0 1.0 -3.6 2.1 2.5 -0.5 -1.1 -0.4
Vascular/heart problems diagnosed by doctor 0.8 2.2 4.6 1.5 -0.8 2.1 1.9 1.1 -1.6 -0.5 -1.5 1.6
Cholesterol lowering medication 0.8 1.2 3.2 -0.8 -1.8 -1.1 -1.2 0.5 0.1 1.6 0.8 -1.0
Medication: Omeprazole (e.g. Zanprol) 0.5 0.6 1.5 0.6 -1.2 0.8 -0.6 1.1 0.2 -0.4 0.5 -1.2
Pain experienced in last month 0.9 1.5 3.8 -1.4 -1.2 -1.4 0.9 -1.9 -1.7 0.4 -0.2 0.7
Supplements: Calcium 0.7 0.8 2.5 0.9 -0.6 1.6 0.4 1.4 0.8 -0.1 0.8 -0.4
Basal cell carcinoma (self-reported) 1.2 1.4 4.5 -2.1 0.7 -2.1 -1.1 -0.3 0.6 1.3 0.0 0.5
Heart attack/myocardial infarction (self-reported) 1.2 1.5 6.1 -0.8 1.0 -1.1 -2.5 0.7 1.5 0.8 -1.2 0.2
Deep venous thrombosis (DVT) (self-reported) 0.9 1.2 4.1 1.2 0.9 1.1 1.3 -0.6 -2.0 0.0 0.3 1.0
Heart disease (siblings) 0.5 0.7 3.1 0.2 1.1 -0.1 -0.9 -0.7 -0.6 -0.3 -1.8 0.2
Alcohol drinker status: Previous 0.4 0.5 1.4 0.5 0.6 0.5 0.7 -0.2 -1.2 -0.6 0.3 1.1
Pack years of smoking 1.6 2.3 7.3 -2.4 -0.6 -2.7 -0.2 -1.1 1.0 -1.7 0.6 -1.5
Impedance of whole body 0.6 2.9 9.3 -3.1 -2.8 -1.8 0.7 -1.0 -0.7 -1.6 -0.6 -1.0
Leg fat mass (left) 0.3 1.3 4.2 -0.4 0.2 -0.9 -0.3 0.4 2.1 1.1 1.0 -2.0
Arm predicted mass (left) 0.3 1.5 5.2 1.5 1.3 1.0 1.1 0.3 1.2 -0.1 2.3 -0.6