Hub : Genes

PDLIM1

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.1010	0.0360	0.00078	0.054	NA	0.019	NA	0.023	3.2e-05	NA	9.8e-03	NA	5.0e-03
2	GTEx	Esophagus Muscularis	0.0840	0.0350	0.00730	0.080	NA	0.014	NA	0.055	1.4e-05	NA	4.4e-02	NA	2.8e-04
3	GTEx	Nerve Tibial	0.0867	0.0373	0.00720	0.012	NA	0.009	NA	0.003	4.4e-02	NA	6.7e-02	NA	1.9e-01
4	GTEx	Thyroid	0.0800	0.0360	0.00830	0.004	NA	0.001	NA	0.006	1.5e-01	NA	2.6e-01	NA	1.0e-01
5	METSIM	Adipose	0.0629	0.0268	0.00063	0.005	0.014	0.020	0.018	0.014	4.8e-02	2.9e-03	4.1e-04	9.1e-04	2.5e-03
6	YFS	Blood	0.1151	0.0285	0.00000	0.072	0.061	0.071	0.066	0.072	2.0e-22	2.6e-19	2.6e-22	1.1e-20	2.3e-22
7	TCGA	Kidney Renal Clear Cell Carcinoma	0.0872	0.0378	0.00230	0.013	0.037	0.019	NA	0.019	1.1e-02	5.2e-05	2.8e-03	NA	3.1e-03
8	TCGA	Prostate Adenocarcinoma	0.1014	0.0489	0.00850	-0.003	0.010	0.007	NA	-0.002	8.9e-01	2.7e-02	5.1e-02	NA	6.0e-01
9	TCGA	Uterine Corpus Endometrial Carcinoma	0.1970	0.0880	0.00760	0.165	0.098	0.157	NA	0.147	2.4e-05	1.1e-03	3.9e-05	NA	6.8e-05

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Bipolar Disorder (2018)	0.4	0.7	1.9	-1.4	1.0	-0.6	-0.2	0.1	0.7	1.0	0.6	1.1
Bipolar Disorder or Schizophrenia	0.4	1.1	3.3	-1.8	-0.6	-1.1	1.1	0.1	-0.1	1.5	-1.1	-0.0
Depressed Affect (Nagel 2018)	0.7	1.4	5.7	0.4	-0.6	0.1	-0.7	1.3	2.4	0.3	1.7	-1.3
Depression (Nagel 2018)	1.0	1.5	4.8	1.0	-0.7	0.6	-1.6	0.9	1.7	0.5	-0.0	-2.2
Intelligence (Savage-Jansen 2018)	0.2	0.5	1.5	-0.2	-0.1	-0.7	-1.0	0.9	-0.4	-0.4	0.3	1.2
Neuroticism (Nagel 2018)	0.8	1.9	6.1	0.6	-0.8	0.7	-0.9	1.6	2.5	0.7	2.1	-1.0
Schizophrenia (2018)	0.7	1.5	3.5	-1.2	-1.6	-0.9	1.6	0.0	-0.7	1.0	-1.9	-0.9
Schizophrenia vs Biploar Disorder	1.9	2.6	9.9	1.3	-1.7	0.5	-0.3	-0.5	0.6	-2.8	-0.2	-3.1
Worry (Nagel 2018)	0.5	1.1	3.4	0.1	-0.6	0.9	-1.1	0.5	1.8	-0.0	1.2	-1.4
Alzheimer’s Disease (in mother)	0.9	1.1	3.2	-0.2	0.1	0.0	-0.4	1.8	1.6	1.2	1.5	0.1
Alzheimer’s Disease (in father)	0.6	0.7	1.9	0.3	1.2	0.4	0.5	-0.8	-0.7	-1.0	-1.4	0.4
Alzheimer’s Disease (including proxy)	0.3	0.5	1.7	0.4	1.3	0.7	0.1	0.5	0.7	-0.3	-0.1	1.0
Crohns Disease (2017)	0.3	0.6	4.1	0.1	-0.3	-0.6	0.1	0.5	0.2	0.4	2.0	-0.6
Irritable Bowel Disease (IBD)	0.4	0.9	2.6	1.3	-0.6	1.0	0.2	1.0	0.3	0.7	1.6	-0.8
Ulcerative Colitis (UC)	0.6	1.2	3.2	1.8	-0.8	1.7	0.3	1.5	0.5	0.5	0.5	-1.0
Major Depression (MDD)	0.5	0.6	1.5	1.1	0.5	0.9	-0.6	0.4	-0.1	0.2	-1.2	1.0
Reaction Time	0.8	1.5	7.1	0.8	1.1	0.5	-0.0	0.3	0.7	2.7	-1.9	0.3
Verbal and Numeric Reasoning (VNR)	0.4	1.0	3.7	-1.1	-0.6	-1.4	-0.6	-0.8	-1.0	-1.9	-0.2	0.3
Breast Cancer	1.2	2.9	6.3	2.5	-0.5	2.1	-2.4	1.2	2.1	-0.7	-0.2	-1.9
Ovarian Cancer	0.4	0.5	1.2	-1.0	0.1	-1.1	-1.0	0.5	0.8	-0.5	0.3	0.1
Prostate Cancer	0.7	0.9	7.1	0.0	-0.3	0.2	-0.5	0.6	0.6	0.4	-2.7	-0.2
Age at First Birth	0.5	0.7	1.7	0.4	-0.0	1.2	0.8	1.3	-0.5	0.2	0.8	-1.3
Bipolar Disorder (2011)	0.7	0.7	4.5	-0.4	0.9	-0.1	0.2	-0.2	0.2	2.1	-0.2	1.0
Body Mass Index (BMI) (2010)	0.6	0.8	2.0	-0.5	0.0	-1.1	1.4	-0.2	-0.8	0.4	1.2	1.2
Coronary Artery Disease (CAD)	0.3	0.4	1.3	0.7	-0.6	0.6	-0.1	0.7	-0.4	0.4	-1.1	-0.5
Crohns Disease (2012)	0.6	0.9	2.2	-0.7	-0.7	-0.8	1.4	-0.1	-1.5	0.6	1.3	0.5
Mean Putamen Volume	0.6	0.7	2.7	-0.1	-1.6	-0.2	-0.3	-1.2	-0.9	-0.7	-0.2	-0.6
Fasting Glucose	2.0	2.4	7.7	-1.7	0.2	-2.8	-0.8	-1.8	-0.3	-1.0	-2.4	0.5
HbA1C	0.5	0.5	1.3	-0.7	0.8	-0.9	-0.8	1.1	0.8	0.4	-0.0	0.1
HDL Cholesterol	0.2	0.4	1.5	0.3	0.4	0.6	1.2	-0.6	-0.1	-1.1	-0.3	0.2
LDL Cholesterol	0.6	0.9	2.7	-0.4	0.4	-0.6	1.7	-0.2	-1.5	-0.5	1.0	1.1
Lupus	0.4	0.7	2.9	-0.2	-1.7	0.1	0.1	-0.5	-0.1	0.4	-0.6	-1.5
Neuroticism (2016)	1.6	2.4	6.6	2.2	1.2	1.7	0.1	2.6	1.6	1.4	0.9	0.7
Primary Biliary Cirrhosis	0.6	0.8	1.7	-0.6	-0.5	-1.3	1.2	-1.1	-0.6	0.3	-1.1	0.6
Rheumatoid Arthritis	0.5	0.7	2.0	-1.4	0.2	-0.7	0.4	-1.0	0.2	0.8	-0.4	-1.4
Schizophrenia (2014)	0.5	1.1	3.7	-1.1	-0.5	-0.8	1.9	0.3	-1.1	0.4	-1.6	-0.1
Triglycerides	0.2	0.3	1.3	0.5	1.1	0.3	0.8	0.4	0.8	-0.2	0.2	-0.2
Type 2 Diabetes (T2D) (2012)	0.5	0.6	1.7	-0.2	0.4	-0.4	-0.4	-0.8	0.8	-1.3	1.2	-0.7
Ulcerative Colitis	0.1	0.2	0.4	0.5	-0.4	0.4	-0.0	-0.0	0.1	0.6	0.6	-0.5
Blood Eosinophil Count	0.3	2.3	6.1	0.6	-2.5	0.9	-1.5	1.9	1.2	2.1	0.6	-1.2
Blood Platelet Count	0.4	5.0	14.4	0.8	-0.7	1.2	0.7	3.8	2.4	2.3	2.8	-3.0
Blood Red Count	0.7	6.3	21.9	-2.3	-1.9	-1.7	-0.3	2.8	4.7	1.7	1.8	-3.0
Blood White Count	1.9	14.2	36.4	-4.9	-2.8	-3.5	-2.2	3.8	6.0	0.4	2.4	-4.7
Heel T-Score	0.4	2.9	10.8	3.3	1.5	2.6	-1.0	-0.0	-0.6	-0.8	1.9	0.6
BMI	0.2	1.0	4.5	-0.1	0.7	-1.1	-0.1	0.7	0.8	2.1	1.2	0.4
Height	0.2	3.7	10.8	-1.5	-2.7	-0.4	0.6	-3.2	-0.6	-3.3	-0.6	-1.2
Waist Hip Ratio (WHR)	0.7	3.4	10.7	-1.1	0.2	-0.5	-1.3	-0.9	2.2	-3.3	0.8	-3.2
Systolic Blood Pressure	0.6	3.1	7.6	-2.4	0.7	-2.2	-1.2	-1.4	2.8	1.3	1.1	-1.7
Smoking Status	0.2	0.5	3.4	-0.1	-0.4	0.1	-0.1	-0.6	0.1	-0.1	-1.8	-0.6
Allergy or Eczema	0.6	1.7	3.8	1.9	0.7	1.6	0.6	0.5	-0.9	-0.3	-1.9	1.7
Cardiovascular Disease	0.7	2.3	6.2	-1.6	0.1	-2.0	-2.5	-1.5	1.1	1.3	1.2	-1.0
Hypothyroidism (self reported)	0.2	0.5	2.8	-0.1	0.3	-0.4	0.3	-0.0	-1.1	0.1	-0.1	1.7
Respiratory disease	0.8	1.7	3.1	1.8	-1.5	1.1	-1.6	1.6	0.7	0.2	-1.2	-1.2
Type 2 Diabetes (T2D) (2018)	0.2	0.4	1.6	-0.4	0.4	-0.6	-0.7	-0.5	1.3	0.1	0.4	-0.4
Lung FEV1/FVC ratio	0.7	3.6	14.4	-1.7	0.9	-1.0	0.7	-3.8	-3.0	-1.6	-1.0	-0.8
Lung FVC	0.3	1.4	3.0	-1.7	0.6	-1.3	-1.6	0.6	1.0	0.6	1.7	-0.8
Neuroticism	1.8	4.3	13.7	1.0	-0.8	1.2	-2.7	2.5	3.7	2.0	1.2	-1.7
Chronotype (morning person)	0.5	1.2	4.6	0.2	1.6	0.1	-0.1	-0.2	1.8	-2.1	-0.4	-0.4
Hair Pigment	0.0	0.8	3.9	-0.1	1.1	-0.2	-0.3	0.4	0.8	0.8	0.6	2.0
Tanning	0.1	1.0	2.9	-1.2	0.4	-0.7	-0.0	-1.3	-0.5	-1.7	-1.6	0.3
Hand grip strength (left)	1.3	3.4	6.6	1.9	0.9	2.5	2.3	0.8	-1.4	1.7	1.4	2.6
Number of treatments/medications taken	0.4	0.7	1.9	-0.6	0.1	-1.3	-1.4	-1.0	0.3	-0.4	-0.8	-0.7
Average weekly spirits intake	0.7	0.8	3.6	-0.3	1.5	-0.4	-0.0	0.4	-0.5	0.2	1.0	1.9
Sensitivity / hurt feelings	0.7	1.1	2.1	1.2	1.2	0.5	-0.2	1.1	1.1	1.5	0.6	1.5
Frequency of depressed mood in last 2 weeks	0.3	0.5	0.9	-0.1	-0.7	-0.5	-0.5	0.8	0.9	0.7	0.4	-1.0
Hearing difficulty/problems: Yes	2.2	3.4	14.1	-1.6	-0.2	-1.7	-3.8	-0.4	2.3	0.1	-1.1	-2.1
Relative age of first facial hair	0.2	0.4	1.1	-0.0	1.1	0.8	-0.2	-0.5	0.2	-0.8	-0.8	-0.5
Other serious medical condition/disability diagnosed by doctor	0.9	1.2	6.0	-1.5	1.1	-2.5	0.1	-0.7	-0.0	-0.5	0.3	-0.1
Ever used hormone-replacement therapy (HRT)	0.4	0.5	2.5	-0.1	-0.4	-0.5	-0.7	0.6	1.6	0.1	-0.3	-0.5
Ever had hysterectomy (womb removed)	0.5	0.6	2.2	-0.3	-0.9	-0.9	-0.5	-0.0	0.8	1.5	-0.3	-0.6
Systolic blood pressure, automated reading	0.8	2.2	8.9	-1.1	2.0	-1.4	0.1	-1.0	3.0	0.6	1.2	-0.9
Eye problems/disorders: Diabetes related eye disease	0.7	0.7	2.3	-0.6	-0.6	-0.7	-1.1	-0.5	0.6	0.2	1.5	-1.1
Angina	1.1	1.5	5.9	0.9	-0.7	0.9	-2.2	0.6	0.3	0.0	0.3	-2.4
Medication for hormone replacement therapy	1.3	1.4	2.9	1.5	-1.7	1.5	-0.3	0.5	0.3	-0.8	-1.1	-1.6
Vitamin and mineral supplements	0.2	0.3	1.2	-0.3	-0.0	-1.1	-0.7	-0.2	0.2	0.8	-0.2	-0.1
Supplements: Zinc	1.1	1.2	2.8	1.5	0.1	1.7	-0.4	1.7	1.2	0.7	-0.8	-0.1
Medication: Co-codamol	0.7	0.8	3.3	-0.1	0.3	-0.9	-0.5	0.5	-1.0	0.5	1.8	0.9
Medication: Metformin	1.1	1.6	6.4	0.7	0.6	0.5	-1.3	0.8	2.5	1.2	0.6	-1.6
Diabetes (father)	1.1	1.3	2.8	-1.3	-1.0	-1.7	-0.2	-1.1	-0.8	-1.0	1.4	-1.2
Diabetes (mother)	0.3	0.4	1.9	-0.0	-0.1	0.3	-0.2	0.1	-1.4	0.4	1.1	-0.3
Severe depression (siblings)	0.9	1.0	4.4	-2.1	-0.3	-1.6	0.7	-0.5	-0.8	-0.1	-0.6	-0.2
Pack years adult smoking proportion	1.5	2.3	7.6	-2.5	-0.5	-2.8	-0.1	-1.2	0.7	-1.9	0.5	-1.2
Impedance of leg (right)	0.8	3.7	10.9	-2.9	-3.3	-1.9	0.9	-1.2	-0.2	-2.0	-0.2	-2.1
Leg fat-free mass (left)	0.2	1.0	2.6	1.4	1.6	1.1	0.6	0.2	0.2	0.4	1.4	0.6
Trunk fat percentage	0.3	1.3	3.0	-1.4	-0.3	-1.5	-0.4	0.5	1.7	1.4	0.6	-1.5
Hand grip strength (right)	1.2	3.3	13.0	0.0	1.0	0.9	3.6	0.4	-1.8	1.0	1.9	2.5
Townsend deprivation index at recruitment	0.8	1.2	4.0	-0.3	-1.0	-0.2	-1.3	0.1	1.6	-0.1	-1.1	-2.0
Current tobacco smoking	0.9	1.5	6.2	-0.8	0.7	-0.7	2.5	-0.6	-1.9	-0.4	-0.0	1.1
Average weekly fortified wine intake	0.7	0.8	2.4	-0.9	1.0	-1.1	0.0	-1.5	0.4	-1.2	-0.1	-0.1
Maternal smoking around birth	0.9	1.3	3.0	1.4	-1.7	0.2	-0.7	1.7	0.9	1.0	-1.3	0.1
Fed-up feelings	0.3	0.5	1.5	0.3	-0.5	-0.4	-0.8	0.6	1.2	1.0	0.2	-0.9
Frequency of unenthusiasm / disinterest in last 2 weeks	1.4	1.9	3.9	0.4	-1.9	0.2	-1.3	1.5	1.5	1.7	0.0	-2.0
Relative age voice broke	0.3	0.4	1.5	-0.1	-1.0	0.3	1.2	-0.0	-1.0	0.1	-0.4	-0.4
Taking other prescription medications	0.4	0.7	2.6	-0.0	0.1	-0.4	-1.3	-1.0	0.4	-0.8	-1.6	0.2
Age when periods started (menarche)	0.3	0.8	6.2	-0.2	-0.3	-0.3	-2.5	-0.7	0.4	-0.1	-0.5	-0.1
Bilateral oophorectomy (both ovaries removed)	0.7	0.8	2.7	0.4	-1.2	0.7	-0.4	1.2	0.8	1.6	-0.4	-0.5
Heel bone mineral density (BMD) T-score, automated (left)	0.6	1.3	4.7	1.5	0.7	0.7	0.9	-0.3	-2.2	0.2	0.0	1.6
Tinnitus: Yes, but not now, but have in the past	0.1	0.1	0.4	0.5	0.3	0.4	-0.6	-0.1	-0.3	0.3	0.1	0.5
Qualifications: CSEs or equivalent	0.6	0.8	2.1	1.1	-1.4	0.8	0.2	0.5	-0.8	1.1	-1.1	0.6
Serious illness, injury or assault to yourself	0.4	0.5	1.6	-1.3	-0.0	-1.0	0.6	-0.7	0.3	0.5	-0.7	-0.4
High blood pressure	1.0	2.7	6.7	-1.7	0.8	-2.6	-1.6	-1.7	1.6	0.1	2.0	-1.5
Hayfever, allergic rhinitis or eczema	0.3	0.6	2.8	0.3	-0.3	0.2	0.6	-0.3	-0.9	-0.6	-1.7	1.1
Multivitamins +/- minerals	0.8	1.0	2.9	0.8	0.6	1.7	0.5	1.5	-0.6	-0.2	1.4	0.6
Stomach or abdominal pain in last month	0.6	0.8	3.7	0.3	0.0	0.7	0.0	0.4	1.3	-1.9	-0.7	-0.7
Supplements: Glucosamine	0.4	0.5	2.0	0.1	0.8	-0.1	0.8	-0.1	-0.3	0.9	0.1	1.4
Diverticular disease/diverticulitis (self-reported)	0.7	0.8	2.0	1.4	-0.7	1.2	-1.1	0.5	-0.7	-1.0	-0.4	-0.1
Medication: Atenolol	1.0	1.2	5.5	-0.8	-0.3	-0.7	-0.6	0.0	1.7	-0.8	-0.5	-2.3
Medication: Levothyroxine sodium	0.6	1.0	2.4	1.5	1.3	1.2	-1.4	-0.9	0.4	-0.7	-0.6	0.2
Sitting height	0.2	1.5	5.8	1.0	0.3	1.4	0.3	-1.7	-0.4	-2.4	-0.9	1.0
Chronic bronchitis/emphysema (father)	1.8	2.1	5.6	0.9	0.5	0.6	-2.3	-0.6	1.8	-0.2	-2.4	-1.6
High blood pressure (mother)	1.2	1.7	5.1	-1.8	1.7	-1.3	-0.1	0.3	0.5	0.9	2.3	0.8
Body mass index (BMI)	0.3	1.3	3.8	0.5	1.3	-0.4	-0.4	0.9	1.9	1.9	0.9	-0.8
Impedance of leg (left)	0.7	3.5	9.2	-2.9	-3.0	-1.9	0.7	-1.0	0.5	-1.9	-0.4	-2.3
Leg predicted mass (left)	0.2	1.0	2.4	1.5	1.6	1.1	0.6	0.3	0.2	0.5	1.3	0.6
Trunk fat mass	0.2	1.1	3.5	-0.9	0.1	-1.0	-0.2	0.3	1.9	0.8	0.9	-1.6
Waist circumference	0.5	1.7	6.9	-0.1	0.8	-0.7	-1.0	0.8	2.6	0.2	1.4	-1.9
Number of incorrect matches in round	1.4	2.3	7.3	2.1	-0.4	2.7	-2.2	1.7	0.9	0.6	-0.2	-0.0
Past tobacco smoking	0.9	1.6	8.6	0.9	1.4	0.4	1.4	0.3	0.2	-1.1	2.9	0.3
Alcohol usually taken with meals	0.4	0.6	1.6	-1.2	0.9	0.2	0.1	0.5	0.7	-0.7	1.1	-1.0
Nervous feelings	0.9	1.6	3.7	1.1	-1.9	1.7	-0.8	1.5	1.0	1.3	0.7	-0.7
Frequency of tenseness / restlessness in last 2 weeks	0.6	1.0	2.8	-0.7	-0.1	-0.6	-0.7	0.9	1.7	0.1	1.1	-1.5
Hearing difficulty/problems with background noise	0.9	1.5	5.7	-1.9	0.0	-2.4	-0.3	-0.9	0.9	0.9	-1.1	-0.5
Hair/balding pattern: Pattern 2	0.9	1.2	3.9	0.2	-1.4	0.5	-0.9	0.7	1.4	-0.3	-0.9	-2.0
Had menopause	0.6	0.8	3.8	0.2	-0.9	0.1	-0.4	0.0	1.1	1.9	-0.6	-0.6
Had other major operations	0.2	0.2	0.7	0.1	0.1	0.1	0.2	-0.4	0.6	-0.6	-0.8	-0.7
Forced vital capacity (FVC)	0.4	1.5	4.3	-2.0	-0.3	-1.3	0.4	-0.8	0.4	-0.8	2.1	-1.1
Heel bone mineral density (BMD) T-score, automated (right)	0.4	1.0	5.0	-0.0	0.3	-0.0	1.4	0.0	-2.2	0.5	1.1	0.9
Ever unenthusiastic/disinterested for a whole week	1.8	2.3	5.2	0.9	-0.4	1.2	-2.3	0.7	2.2	2.0	-0.8	-1.7
Qualifications: None of the above	0.5	1.1	3.3	1.1	1.3	0.0	-1.8	-0.5	0.8	1.4	-0.3	-0.4
Financial difficulties in last 2 years	0.7	1.0	5.7	-0.2	-0.6	-0.2	-0.9	-0.2	0.8	2.4	-0.8	-0.9
Mouth/teeth dental problems	1.2	1.9	6.2	-1.8	-2.5	-1.3	0.4	-0.9	-1.6	0.0	0.0	-1.3
Heart attack	0.9	1.2	4.7	-0.6	1.0	-0.8	-2.2	0.8	1.2	0.6	-1.1	0.3
Allergy	0.2	0.6	1.3	-0.8	1.0	-0.8	-0.1	-0.4	0.9	0.6	1.2	-0.5
Pain all over the body in last month	1.0	1.1	3.2	-1.2	-0.5	-1.2	0.7	-1.2	-1.0	-0.6	1.8	0.0
Diabetes (self-reported)	1.0	1.5	3.1	-1.1	-0.1	-1.4	-1.7	-1.1	1.8	0.5	0.6	-1.6
Hayfever/allergic rhinitis (self-reported)	0.8	1.0	5.7	-0.3	1.1	-0.2	0.2	0.7	-1.0	0.1	-0.7	2.4
Medication: Ramipril	1.4	1.8	4.2	-0.3	-2.0	-0.2	-2.0	-1.3	-0.7	1.4	-0.2	-2.0
Medication: Simvastatin	1.4	2.1	9.9	-0.1	-1.8	-0.2	-3.1	0.6	1.1	1.5	0.7	-1.3
Fluid intelligence score	0.8	1.8	5.3	-2.1	-0.6	-2.1	0.0	-0.2	-0.5	-2.3	-0.9	0.2
Illnesses of siblings	2.8	4.0	19.4	0.6	-4.4	1.3	-1.1	2.1	0.4	2.6	0.3	-1.1
Neuroticism score	0.7	1.5	3.7	0.5	-0.3	0.3	-1.7	1.2	1.9	1.7	1.2	-0.7
Weight	0.2	0.8	3.2	0.5	1.0	0.1	0.2	0.3	1.8	0.5	1.2	-0.9
Impedance of arm (right)	0.4	2.0	5.6	-2.4	-2.3	-1.1	0.0	-1.2	-1.6	-0.8	-0.9	-0.2
Arm fat percentage (right)	0.2	0.8	2.8	-0.6	0.7	-0.9	-0.3	0.3	1.2	1.7	0.3	-0.9
Trunk fat-free mass	0.2	1.3	3.2	1.7	1.4	1.4	0.6	-0.0	0.8	-0.8	1.8	-0.2
Hip circumference	0.1	0.6	3.3	0.3	0.5	-0.2	0.4	0.3	1.8	0.6	0.4	-0.7
Time employed in main current job	1.1	1.3	3.1	1.0	-1.0	1.3	1.7	0.5	-1.7	1.0	0.3	-0.7
Alcohol intake versus 10 years previously	0.4	0.7	1.6	1.2	0.5	-0.2	0.5	-0.8	-1.3	-0.4	-1.0	0.8
Father’s age at death	1.3	1.7	4.5	-2.1	0.8	-1.6	-0.9	-1.2	0.4	-2.0	-1.1	0.5
Worrier / anxious feelings	0.5	1.0	2.3	-0.9	-0.9	-0.8	-0.8	-0.6	1.4	-0.1	1.2	-1.5
Frequency of tiredness / lethargy in last 2 weeks	1.0	1.5	3.9	-0.4	-1.7	0.3	-0.7	1.3	0.8	0.5	2.0	-1.9
Falls in the last year	0.5	0.7	2.5	-0.5	0.6	-0.4	1.6	-1.0	-1.0	-0.1	0.8	0.7
Hair/balding pattern: Pattern 3	0.7	1.1	4.2	-0.0	0.9	-1.1	0.2	0.0	-0.7	1.6	2.0	0.6
Number of live births	0.8	1.1	4.6	-0.3	0.5	0.1	-0.1	1.5	2.1	1.4	0.2	-1.0
Forced expiratory volume in 1-second (FEV1)	0.4	1.2	3.0	-1.7	-0.5	-0.9	0.4	-1.3	-0.4	-0.8	1.7	-1.0
Pulse rate	0.8	1.4	3.4	1.8	1.5	0.3	0.9	-1.5	-0.5	-1.6	-0.5	0.9
Happiness	0.2	0.2	0.8	0.4	0.5	0.6	0.1	0.5	0.9	0.2	0.6	-0.2
Noisy workplace	0.9	1.2	2.9	-0.7	-1.7	-0.6	-1.2	-0.8	-0.9	0.7	0.7	-1.7
Qualifications: A levels/AS levels or equivalent	0.6	1.3	4.7	-1.5	-0.5	-1.0	0.4	-0.9	-0.6	-0.0	-1.3	2.2
Serious illness, injury or assault of a close relative in last 2 years	1.4	1.7	6.7	0.5	-1.7	0.4	-2.6	0.0	1.2	0.3	-1.5	-1.1
Mouth/teeth dental problems: Dentures	1.5	2.5	9.3	1.8	1.4	0.9	-2.4	0.7	3.0	0.2	-0.7	-0.6
Asthma	0.7	1.4	3.7	1.1	-1.1	0.9	-1.7	1.9	0.9	0.3	-1.3	-0.5
Medication: Ibuprofen (e.g. Nurofen)	1.6	2.0	4.1	0.7	-0.6	1.1	1.8	2.0	-1.2	1.3	1.8	1.5
Medication: Cholesterol lowering	1.4	2.1	16.4	0.1	-0.7	0.2	-4.1	-0.8	-0.1	0.9	-0.1	-0.8
Depression (self-reported)	0.8	0.9	2.5	-1.0	1.0	-0.8	-0.3	1.4	1.6	-0.6	-0.5	0.3
Medication: Lansoprazole	0.4	0.5	2.4	-0.4	0.0	-0.6	-0.2	0.0	0.2	1.0	-1.5	0.4
Prospective memory result	0.9	1.1	4.1	-0.1	0.5	0.3	1.6	-1.0	-2.0	0.6	1.1	0.6
Lung cancer (father)	0.8	0.9	2.8	0.5	0.0	0.4	-1.1	1.5	1.7	0.2	-0.0	-1.1
Illnesses of mother	1.6	1.9	4.4	2.1	-0.9	2.1	1.6	0.8	-1.5	-0.2	-1.0	1.3
Forced expiratory volume in 1-second (FEV1), Best measure	0.7	2.4	5.6	-2.0	-1.5	-1.2	0.6	-2.4	-1.5	-0.6	1.4	-1.8
Pulse wave Arterial Stiffness index	1.5	1.8	8.2	1.3	0.9	1.2	0.2	1.5	2.9	-0.6	-0.2	-1.2
Impedance of arm (left)	0.4	2.0	6.3	-2.5	-2.2	-1.3	0.3	-0.8	-1.5	-0.7	-1.3	0.1
Arm fat mass (right)	0.2	0.8	1.8	-0.3	0.9	-0.6	0.2	0.4	1.3	1.4	1.2	-0.9
Trunk predicted mass	0.2	1.3	3.3	1.7	1.3	1.4	0.6	0.1	0.9	-0.8	1.8	-0.2
Standing height	0.2	2.1	10.6	-0.1	-0.3	0.8	1.5	-1.8	-0.2	-3.3	1.1	-0.5
Length of working week for main job	1.9	2.1	5.1	-0.9	0.7	-1.5	1.0	-1.3	-2.2	1.9	-0.5	2.0
Exposure to tobacco smoke at home	1.0	1.1	3.2	0.7	-0.7	0.7	-1.8	0.8	1.6	-0.3	-1.2	-0.8
Breastfed as a baby	0.2	0.3	1.1	-0.4	0.1	0.1	0.8	-0.8	-1.0	0.5	0.1	-0.3
Tense / ‘highly strung’	0.5	0.8	2.7	-0.2	-0.0	0.1	-1.5	0.3	1.7	-0.7	0.3	-1.3
Seen doctor (GP) for nerves, anxiety, tension or depression	0.2	0.3	0.7	-0.6	-0.5	-0.2	-0.1	0.7	0.6	-0.1	-0.6	-0.8
Hair/balding pattern: Pattern 4	0.6	1.3	3.7	1.8	1.1	1.9	-0.3	0.7	-0.3	0.5	-0.4	1.7
Birth weight of first child	1.7	3.0	7.8	-1.2	-2.8	-1.1	1.5	-1.4	-1.9	0.7	1.8	-2.3
Peak expiratory flow (PEF)	0.3	0.6	2.6	-1.6	0.2	-0.7	1.0	0.2	-0.5	-0.8	0.3	0.3
Pulse wave reflection index	0.9	1.2	4.2	-0.3	1.0	0.5	1.3	2.0	1.5	-0.0	1.0	-0.3
Ever highly irritable/argumentative for 2 days	0.5	0.6	1.6	0.9	0.3	0.9	-1.3	0.1	0.7	1.0	-0.2	-0.6
Loud music exposure frequency	0.6	0.6	1.5	-1.2	-0.2	-0.8	-0.9	-0.9	0.6	0.4	-0.2	-1.1
Qualifications: O levels/GCSEs or equivalent	0.6	1.0	2.2	-0.3	-1.5	0.1	0.8	-0.8	-1.5	-1.1	-1.3	0.8
Mouth/teeth dental problems: Bleeding gums	1.1	1.4	5.8	0.4	1.7	0.8	1.2	0.0	-0.7	0.3	-1.2	2.4
Blood clot in the leg (DVT)	0.8	1.1	4.2	1.1	0.6	1.1	1.1	-0.5	-2.0	0.2	0.4	0.9
Medication: Paracetamol	0.9	1.5	3.6	-1.2	0.2	-1.9	1.5	-0.3	1.0	0.2	1.2	-1.9
Headache pain in last month	0.6	1.0	5.6	-1.0	-0.6	-0.3	2.4	1.1	-0.3	0.6	0.7	0.4
Medication for cholesterol, blood pressure or diabetes	1.3	2.2	11.8	1.4	0.1	1.2	3.4	0.6	-1.0	-0.4	-0.9	1.5
Glaucoma (self-reported)	0.7	0.8	2.8	1.0	0.3	1.2	-0.6	0.7	1.7	-0.4	-0.3	-1.0
Gout (self-reported)	0.8	1.1	3.4	0.6	0.4	0.4	0.1	-1.4	-1.7	-1.9	-0.1	-0.7
Hypothyroidism/myxoedema (self-reported)	0.2	0.4	1.4	0.7	1.1	0.4	-0.7	-0.1	-0.3	-0.2	-0.3	1.2
Medication: Amlodipine	0.7	1.0	2.0	-1.4	-0.6	-1.4	-1.3	0.5	0.9	1.2	0.7	0.6
Medication: Ventolin 100micrograms inhaler	1.1	1.4	3.1	-0.3	-1.6	-0.2	-1.8	1.2	0.8	-0.4	-1.5	-1.4
Birth weight	0.7	1.6	4.3	0.4	0.2	0.9	1.4	-1.3	-2.1	1.1	0.2	2.0
Chronic bronchitis/emphysema (mother)	1.2	1.4	6.0	1.3	-2.4	0.4	-0.4	0.5	0.2	-0.7	-1.2	-1.4
High blood pressure (siblings)	2.1	3.0	13.4	-1.4	3.7	-1.7	1.4	-2.1	-0.2	-1.2	-0.9	0.8
Forced vital capacity (FVC), Best measure	0.6	2.1	5.4	-2.3	-1.2	-1.5	0.5	-1.7	-0.8	-0.2	1.7	-1.6
Body fat percentage	0.4	1.6	3.8	-1.4	-0.3	-1.6	-0.4	0.6	2.0	1.4	0.6	-1.8
Leg fat percentage (right)	0.5	1.9	5.8	-1.1	-0.3	-1.6	-0.1	0.5	2.2	1.3	1.0	-2.4
Arm fat-free mass (right)	0.3	1.5	3.3	1.6	1.3	1.2	0.9	0.8	1.8	-0.0	1.8	-0.3
Exposure to tobacco smoke outside home	1.3	1.7	6.1	0.4	-0.1	0.1	-1.2	1.5	2.0	2.5	-1.0	-0.7
Comparative body size at age 10	0.2	0.7	1.5	1.2	0.4	-0.1	-1.0	-0.4	-0.8	1.1	-0.7	0.9
Number of full brothers	1.6	2.0	7.0	-2.6	-0.3	-2.4	0.5	0.3	1.2	1.0	-1.0	-1.2
Worry too long after embarrassment	1.4	2.4	8.9	0.7	-0.1	0.7	0.3	3.0	2.2	1.9	1.5	0.7
Seen a psychiatrist for nerves, anxiety, tension or depression	0.6	0.8	2.3	0.7	-0.7	0.5	-1.4	0.9	1.5	0.6	-1.0	-0.4
Wheeze or whistling in the chest in last year	1.2	2.1	5.1	2.2	-1.1	1.8	-1.8	0.8	0.9	-0.2	-1.3	-1.8
Number of children fathered	1.7	1.9	6.1	0.9	2.5	0.2	1.2	-1.5	0.1	-1.9	1.7	0.2
Reason for reducing amount of alcohol drunk: Health precaution	0.5	0.5	1.8	0.5	1.2	0.8	0.7	0.2	-0.4	0.2	1.3	0.1
Age at first live birth	0.8	1.3	5.4	0.8	-2.3	1.5	-0.2	1.2	-0.2	-0.7	-1.0	-0.8
Pulse wave peak to peak time	1.6	1.9	8.2	-1.4	-0.9	-1.2	-0.2	-1.6	-2.9	0.3	0.3	1.2
Health satisfaction	0.3	0.4	2.5	-0.1	0.2	-0.3	1.6	-0.2	-0.7	0.1	0.8	0.1
Shortness of breath walking on level ground	1.0	1.2	4.2	-0.4	1.7	-1.1	0.0	-2.1	-0.8	-0.4	0.6	0.9
Qualifications: College or University degree	0.2	0.7	2.3	-0.5	-1.5	0.4	0.3	1.4	-0.0	-0.1	1.3	-0.2
Eye problems/disorders: None of the above	1.2	1.3	4.8	0.8	-1.1	1.1	0.3	1.2	-2.2	-0.2	1.4	1.0
Mouth/teeth dental problems: Loose teeth	1.3	1.6	5.3	0.9	0.5	0.4	-0.7	2.3	1.7	-0.3	1.6	-1.3
Emphysema/chronic bronchitis	0.6	0.6	2.3	0.9	-0.6	0.7	-1.5	0.4	0.5	-0.9	0.5	-0.6
Medication for pain relief, constipation, heartburn	0.4	0.7	2.4	0.7	0.5	1.1	-0.9	-0.1	-0.9	0.2	-0.0	1.6
Neck or shoulder pain in last month	0.6	0.8	2.3	1.1	0.8	1.0	-0.8	1.5	1.0	0.7	0.4	0.5
Medication: Blood pressure	1.3	2.3	9.3	-0.9	-0.9	-0.8	-3.1	-0.5	1.3	-0.0	1.2	-2.3
Angina (self-reported)	1.2	1.5	6.4	0.7	-0.7	0.6	-2.4	0.4	0.4	-0.0	0.1	-2.5
Migraine (self-reported)	1.9	2.4	7.7	-1.4	-2.8	-1.7	-1.2	1.4	1.1	1.1	0.9	-1.5
Medication: Ibuprofen	1.4	1.7	4.2	1.7	-0.5	1.7	1.1	2.0	-1.1	0.9	0.9	1.1
Medication: Allopurinol	1.1	1.5	4.1	0.1	-1.4	-0.1	-0.7	-1.5	-1.6	-1.2	-2.0	-0.6
Medication: Omeprazole	0.9	1.0	2.0	1.3	-0.1	1.2	-0.4	0.8	1.1	-1.4	0.5	-1.3
Medication: Seretide 50 evohaler	0.5	0.5	2.4	-0.4	-0.7	0.1	-1.2	1.6	-0.0	-0.2	-0.2	0.4
Mean time to correctly identify matches	1.0	1.8	6.0	0.7	1.3	0.5	-1.2	0.6	1.1	2.5	-2.2	0.6
Heart disease (mother)	1.1	1.3	3.7	0.1	0.7	-0.0	-1.9	-1.4	1.5	0.1	-1.3	-1.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.9	1.1	4.8	0.2	-0.8	0.2	-2.2	-0.7	0.8	-0.3	-1.5	-0.7
Whole body fat mass	0.3	1.2	3.6	-0.9	0.2	-1.1	-0.2	0.5	1.9	1.0	1.1	-1.5
Leg fat mass (right)	0.3	1.3	4.5	-0.4	0.1	-1.0	-0.2	0.4	2.0	1.0	1.1	-2.1
Arm predicted mass (right)	0.3	1.5	3.7	1.6	1.2	1.2	0.8	0.8	1.9	-0.1	1.8	-0.4
Pulse rate, automated reading	0.2	0.6	1.8	1.2	0.6	-0.4	-1.1	-1.3	0.5	-0.4	-0.6	-0.2
Alcohol intake frequency.	0.5	1.1	3.1	-0.5	0.1	-1.2	-1.3	-0.3	1.0	-0.2	1.8	-1.5
Comparative height size at age 10	0.1	0.8	4.8	-0.1	0.3	0.6	0.3	-0.6	0.2	-2.2	1.1	-0.7
Number of full sisters	1.1	1.3	2.3	-1.1	1.4	-1.0	1.3	-0.2	-1.5	0.8	0.6	1.5
Suffer from ‘nerves’	0.6	0.9	2.2	1.2	-0.3	1.5	-0.9	1.2	1.2	-0.0	0.1	-0.6
Overall health rating	0.5	1.1	3.0	0.5	-0.7	-0.0	-0.9	1.7	1.5	1.6	0.3	-0.7
Chest pain or discomfort	1.1	1.6	3.6	1.2	-0.9	0.8	-1.2	1.2	1.5	0.5	-1.5	-1.9
Had major operations	0.9	1.0	2.4	0.6	-1.3	0.0	-1.2	-0.4	0.5	-1.0	-1.2	-1.6
Age at last live birth	1.5	2.2	7.4	1.9	-1.2	2.1	-0.3	2.7	0.7	0.2	-1.4	-0.6
Family relationship satisfaction	0.8	1.0	3.2	-1.1	1.8	-0.9	1.2	0.2	1.4	-0.1	-0.2	0.1
Leg pain on walking	0.4	0.5	1.4	1.0	0.3	1.2	-0.5	0.8	0.8	0.6	-0.1	0.5
Qualifications: NVQ or HND or HNC or equivalent	0.7	0.8	3.4	0.2	-0.1	0.1	1.8	0.3	-1.2	0.0	-1.1	1.0
Commuting to job workplace: Car/motor vehicle	0.6	0.7	1.7	0.5	-0.0	0.7	1.0	0.3	-1.3	1.3	-0.8	0.9
Illness, injury, bereavement, stress in last 2 years	0.1	0.1	0.4	0.5	0.2	-0.2	0.2	0.4	-0.2	-0.7	-0.1	-0.0
Medication: Aspirin	1.0	1.3	4.2	-0.8	-0.3	-1.1	-2.0	0.1	1.2	0.8	-0.9	-1.8
Supplements: Vitamin C	0.4	0.4	1.8	0.1	1.3	0.3	0.6	-0.5	-0.7	0.5	-0.6	0.6
Knee pain experienced in last month	0.3	0.5	1.1	0.1	1.1	-0.5	-0.7	0.3	1.1	0.5	-0.9	-0.6
Hypertension (Self-reported)	1.0	2.7	6.7	-1.8	0.8	-2.6	-2.2	-1.8	1.6	-0.1	1.3	-1.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.2	1.3	3.8	-1.8	-0.2	-1.9	-0.8	-0.6	1.3	-1.3	-0.9	-0.4
Illnesses of father: Heart disease	0.3	0.4	2.2	0.1	-0.4	0.2	0.5	-0.9	-1.5	-0.1	0.2	0.5
Illnesses of siblings: Diabetes	2.0	2.4	9.4	1.8	3.1	1.1	-0.7	0.3	1.2	-2.2	1.1	-0.0
Smoking status: Previous	0.9	1.4	5.0	-0.0	-1.1	0.2	-1.7	0.5	1.1	1.1	-2.2	-0.8
Forced expiratory volume in 1-second (FEV1), predicted	0.5	1.1	3.4	-1.2	0.9	-0.9	1.8	-0.6	-0.2	-0.4	1.4	0.9
Whole body fat-free mass	0.2	1.3	3.0	1.7	1.6	1.4	0.7	0.3	0.7	-0.2	1.7	0.3
Leg fat-free mass (right)	0.2	1.3	3.3	1.8	1.7	1.4	0.4	0.5	0.5	0.5	1.3	0.7
Arm fat percentage (left)	0.2	0.9	3.7	-0.7	0.4	-1.0	-0.1	0.6	1.3	1.9	0.2	-0.8
Average weekly red wine intake	0.3	0.4	2.3	0.2	-0.1	0.4	0.4	0.3	0.4	-1.5	-0.1	-0.7
Handedness (chirality/laterality): Left-handed	0.1	0.1	0.4	0.0	-0.1	0.7	-0.2	-0.4	0.0	-0.2	0.5	0.4
Mood swings	0.4	0.7	2.6	0.5	-0.5	0.6	-0.7	1.3	1.6	-0.1	0.8	-0.0
Loneliness, isolation	1.3	1.7	4.6	-0.2	-1.1	-0.8	-0.8	1.7	1.4	0.9	2.1	-1.7
Long-standing illness, disability or infirmity	1.1	1.8	6.8	-1.7	-0.1	-2.6	-2.0	-0.6	0.5	0.4	-1.1	-0.6
Ever had bowel cancer screening	1.5	1.8	4.7	-1.6	0.1	-1.6	-2.2	1.4	2.0	0.8	-0.4	0.3
Diabetes diagnosed by doctor	1.2	1.9	4.4	-0.7	-1.0	-1.2	-2.0	-0.4	2.1	0.7	1.0	-2.0
Ever had stillbirth, spontaneous miscarriage or termination	0.6	0.6	1.2	-0.4	-1.0	-0.2	-0.8	0.0	0.7	-1.1	-1.1	-0.9
Friendships satisfaction	0.6	0.7	2.9	-0.2	0.9	-0.3	1.6	0.1	1.7	-0.6	-0.3	0.0
Qualifications: nursing, teaching	0.4	0.6	1.7	-0.4	-0.7	-0.6	1.2	0.1	-1.1	-1.3	0.2	-0.1
Commuting to job workplace: Walk	2.1	2.3	7.2	-2.0	0.9	-2.7	0.6	-1.3	0.5	-2.0	1.3	-0.2
Eye problems/disorders: Cataract	1.3	1.5	4.5	-1.4	0.4	-1.9	-0.4	0.2	2.1	1.2	1.1	-0.7
Mouth/teeth dental problems: Mouth ulcers	0.6	1.0	2.5	0.7	1.4	0.7	1.3	0.2	0.9	-0.7	1.6	-0.5
Medication for cholesterol	0.3	0.4	0.8	-0.6	0.9	-0.4	-0.0	0.7	0.6	0.4	-0.7	0.9
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.7	0.9	3.8	0.7	0.6	0.5	0.4	-1.2	0.6	-2.0	-0.5	-0.7
Back pain experienced in last month	1.2	1.7	6.1	0.9	2.5	0.4	-1.1	-0.2	0.9	-2.2	-1.1	-0.2
Mineral and other dietary supplements	0.4	0.5	1.6	0.1	-0.6	-0.0	-1.2	-0.1	-0.4	0.4	1.3	-0.7
Breast cancer (self-reported)	0.5	0.6	1.1	-1.0	0.3	-0.6	1.0	-0.7	-1.0	0.3	-0.4	0.9
Asthma (self-reported)	0.8	1.7	3.4	1.0	-1.5	0.9	-1.8	1.8	1.0	0.2	-1.5	-1.1
Osteoporosis (self-reported)	0.2	0.3	0.7	-0.8	-0.6	-0.3	0.5	0.5	0.5	0.4	0.7	-0.0
Osteoarthritis (self-reported)	1.2	1.6	6.0	0.1	-0.4	-0.3	-2.1	0.8	2.4	0.5	0.4	-1.7
Medication: Aspirin	1.1	1.4	4.4	-0.5	-0.4	-0.9	-2.1	0.7	1.3	1.0	-0.6	-1.8
Medication: Gliclazide	0.4	0.5	1.2	-0.9	-0.1	-1.1	-0.7	-0.2	0.3	0.8	-0.0	-0.9
Illnesses of father: None of the above (group 1)	0.8	1.0	5.4	0.3	-0.1	0.4	0.3	2.3	1.1	1.4	0.5	-0.1
Smoking status: Current	0.8	1.2	4.6	-1.1	0.5	-0.9	2.1	-0.8	-1.7	-0.3	-0.4	0.8
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.6	1.2	3.3	-1.8	-0.8	-1.4	-0.8	-0.8	0.8	-0.1	0.1	-1.6
Whole body water mass	0.2	1.4	3.2	1.8	1.7	1.4	0.7	0.4	0.8	-0.1	1.7	0.3
Leg predicted mass (right)	0.3	1.3	3.5	1.9	1.8	1.5	0.4	0.6	0.6	0.5	1.3	0.7
Arm fat mass (left)	0.2	0.9	2.2	-0.2	0.4	-0.7	0.2	0.5	1.5	1.5	1.0	-1.1
Number of self-reported non-cancer illnesses	0.8	1.3	4.0	-1.3	0.3	-2.0	-1.9	-0.9	0.7	-0.7	-0.0	-0.8
Average weekly champagne plus white wine intake	0.4	0.6	1.8	-0.7	0.2	-0.5	-0.0	0.4	0.7	-0.9	1.2	-1.3
Miserableness	0.5	0.8	2.6	0.5	-0.2	0.3	-0.1	1.1	1.6	1.6	0.4	-0.7
Guilty feelings	0.9	1.3	3.9	-0.1	-2.0	0.0	-0.8	0.8	1.6	1.6	-0.2	-1.4
Wears glasses or contact lenses	1.7	1.9	4.3	-0.4	-1.1	-1.6	-2.1	-1.5	0.8	-1.7	-0.6	-1.7
Ever taken oral contraceptive pill	0.6	0.7	1.3	-0.9	-0.6	-1.0	0.6	-1.1	-1.0	-0.9	0.0	0.2
Hearing aid user	1.1	1.2	3.8	-0.0	1.0	-0.6	0.1	-2.0	-1.1	-1.8	-0.9	0.6
Mother’s age at death	0.4	0.5	1.5	-0.6	0.2	-0.4	-1.1	-0.7	0.6	-1.2	-0.1	-0.5
Financial situation satisfaction	0.5	0.7	1.2	-1.1	-1.0	-0.8	-0.3	-0.9	-0.2	0.8	0.8	-0.8
Tinnitus: Yes, now most or all of the time	0.3	0.3	1.4	-0.1	-0.3	-0.1	-0.2	-0.1	0.6	-0.6	0.7	-1.2
Commuting to job workplace: Public transport	1.1	1.3	2.5	1.6	-0.4	1.3	-0.1	1.5	1.6	-1.0	-0.9	-0.7
Eye problems/disorders: Glaucoma	0.3	0.3	0.9	0.7	0.4	1.0	-0.3	0.0	0.4	-0.6	-0.4	-0.6
Medication: Blood pressure	0.2	0.4	2.0	0.1	0.6	-0.1	0.6	0.1	0.4	0.7	1.4	-0.0
Pain type(s) experienced in last month: Hip pain	0.4	0.5	3.0	0.0	1.7	-0.0	0.1	-0.2	0.1	-0.8	1.1	-0.2
Supplements: Fish oil (including cod liver oil)	0.5	0.7	2.6	-0.6	-0.4	-0.3	1.6	-0.3	-1.0	0.4	-0.3	1.4
High cholesterol (Self-reported)	1.1	1.9	12.0	-0.8	-1.1	-0.4	-3.5	-0.5	0.7	1.1	-0.3	-1.0
Medication: Bendroflumethiazide	0.5	0.7	3.1	-0.4	1.8	-0.8	0.2	0.0	-0.0	0.5	1.5	0.6
Medication: Paracetamol	0.9	1.4	4.8	-1.4	0.3	-2.2	1.2	-1.1	0.4	-0.4	0.7	-1.6
Medication: Lisinopril	0.2	0.3	1.6	-0.2	0.6	-0.6	-0.4	-0.2	0.3	0.3	1.3	0.5
Medication: Atorvastatin	0.6	0.7	3.2	-0.9	-0.1	-0.8	-1.1	0.3	-0.8	1.8	0.3	0.1
Illnesses of father: High blood pressure	0.9	1.1	2.5	-1.1	0.4	-1.0	1.6	-1.4	-1.4	-0.4	1.1	-0.2
Alcohol drinker status: Never	0.2	0.2	0.8	0.6	0.2	0.0	0.1	0.2	0.9	-0.0	0.1	-0.7
Ever smoked	0.6	1.0	3.5	-0.8	-1.5	-0.3	-0.8	-0.5	-0.9	0.6	-1.9	0.0
Basal metabolic rate	0.2	1.1	2.9	1.4	1.5	1.1	0.8	0.3	0.9	0.0	1.7	-0.0
Leg fat percentage (left)	0.6	2.0	6.4	-1.1	-0.3	-1.5	-0.4	0.4	2.4	1.3	0.8	-2.5
Arm fat-free mass (left)	0.3	1.5	5.2	1.2	1.3	0.9	0.7	0.5	1.8	-0.3	2.3	-0.8
Number of operations (self-reported)	0.6	0.9	4.4	0.4	-1.2	-0.2	-0.4	-0.1	0.6	-0.9	-0.4	-2.1
Average weekly beer plus cider intake	0.2	0.3	1.0	0.3	0.6	-0.4	0.7	-0.1	-0.0	0.7	1.0	-0.3
Irritability	0.2	0.3	1.3	0.5	0.0	-0.2	-1.1	-0.6	0.3	-0.5	0.3	-0.9
Risk taking	0.7	1.1	2.1	-1.4	1.3	-1.2	0.9	1.4	0.1	1.1	0.2	0.5
Ever had prostate specific antigen (PSA) test	0.7	0.8	2.0	1.1	1.3	1.3	-0.6	1.4	0.1	0.1	0.4	0.7
Fractured/broken bones in last 5 years	0.7	0.9	2.1	-1.3	0.3	-1.2	1.4	-0.0	0.7	-1.5	0.4	-0.0
Age started oral contraceptive pill	0.3	0.4	1.2	0.5	0.5	0.3	-1.0	-0.4	0.2	1.1	0.1	0.4
Diastolic blood pressure, automated reading	0.4	1.1	3.1	-0.6	0.8	-1.1	1.4	-0.6	1.3	0.6	1.8	-0.2
Ever depressed for a whole week	2.5	3.1	10.7	1.0	-0.2	0.8	-3.3	0.8	2.7	1.5	-2.1	-1.2
Unable to work because of sickness or disability	0.3	0.4	2.1	0.6	1.4	0.1	0.8	-0.1	-0.1	-0.4	-0.3	0.0
Commuting to job workplace: Cycle	1.0	1.2	2.8	-1.6	-0.6	-1.4	0.8	-1.7	-1.6	-0.2	0.5	0.3
Myopia	2.2	3.2	13.0	1.4	-1.0	1.0	-3.6	2.1	2.5	-0.5	-1.1	-0.4
Vascular/heart problems diagnosed by doctor	0.8	2.2	4.6	1.5	-0.8	2.1	1.9	1.1	-1.6	-0.5	-1.5	1.6
Cholesterol lowering medication	0.8	1.2	3.2	-0.8	-1.8	-1.1	-1.2	0.5	0.1	1.6	0.8	-1.0
Medication: Omeprazole (e.g. Zanprol)	0.5	0.6	1.5	0.6	-1.2	0.8	-0.6	1.1	0.2	-0.4	0.5	-1.2
Pain experienced in last month	0.9	1.5	3.8	-1.4	-1.2	-1.4	0.9	-1.9	-1.7	0.4	-0.2	0.7
Supplements: Calcium	0.7	0.8	2.5	0.9	-0.6	1.6	0.4	1.4	0.8	-0.1	0.8	-0.4
Basal cell carcinoma (self-reported)	1.2	1.4	4.5	-2.1	0.7	-2.1	-1.1	-0.3	0.6	1.3	0.0	0.5
Heart attack/myocardial infarction (self-reported)	1.2	1.5	6.1	-0.8	1.0	-1.1	-2.5	0.7	1.5	0.8	-1.2	0.2
Deep venous thrombosis (DVT) (self-reported)	0.9	1.2	4.1	1.2	0.9	1.1	1.3	-0.6	-2.0	0.0	0.3	1.0
Heart disease (siblings)	0.5	0.7	3.1	0.2	1.1	-0.1	-0.9	-0.7	-0.6	-0.3	-1.8	0.2
Alcohol drinker status: Previous	0.4	0.5	1.4	0.5	0.6	0.5	0.7	-0.2	-1.2	-0.6	0.3	1.1
Pack years of smoking	1.6	2.3	7.3	-2.4	-0.6	-2.7	-0.2	-1.1	1.0	-1.7	0.6	-1.5
Impedance of whole body	0.6	2.9	9.3	-3.1	-2.8	-1.8	0.7	-1.0	-0.7	-1.6	-0.6	-1.0
Leg fat mass (left)	0.3	1.3	4.2	-0.4	0.2	-0.9	-0.3	0.4	2.1	1.1	1.0	-2.0
Arm predicted mass (left)	0.3	1.5	5.2	1.5	1.3	1.0	1.1	0.3	1.2	-0.1	2.3	-0.6