TWAS hub - PEAK1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1480	0.0380	6.7e-16	0.165	0.145	0.157	0.149	0.169	1.2e-19	2.6e-17	1.3e-18	8.8e-18	4.3e-20
2	GTEx	Adipose Subcutaneous	0.0510	0.0250	9.5e-03	0.030	NA	0.014	NA	0.020	1.7e-03	NA	2.2e-02	NA	8.6e-03
3	GTEx	Artery Tibial	0.0686	0.0322	3.7e-03	0.002	NA	0.005	NA	0.006	2.0e-01	NA	1.1e-01	NA	9.5e-02
4	GTEx	Brain Cerebellum	0.2680	0.0910	9.9e-05	0.037	NA	0.059	NA	0.138	2.9e-02	NA	7.9e-03	NA	7.2e-05
5	GTEx	Brain Hippocampus	0.2339	0.1131	2.5e-03	0.048	NA	0.022	NA	0.022	2.8e-02	NA	9.9e-02	NA	9.9e-02
6	GTEx	Brain Nucleus accumbens basal ganglia	0.1720	0.0710	3.5e-03	0.121	NA	0.041	NA	0.085	4.0e-04	NA	3.0e-02	NA	2.8e-03
7	GTEx	Ovary	0.2060	0.0830	2.1e-03	0.019	NA	0.004	NA	0.039	1.1e-01	NA	2.5e-01	NA	4.0e-02
8	GTEx	Thyroid	0.1080	0.0350	5.6e-06	0.050	NA	0.061	NA	0.080	1.1e-04	NA	1.9e-05	NA	9.6e-07
9	METSIM	Adipose	0.0505	0.0201	9.8e-05	0.013	0.025	0.015	0.027	0.018	3.6e-03	8.6e-05	2.3e-03	6.2e-05	9.2e-04

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Crohns Disease (2017)	5.5	12.1	22.6	1.4	3.4	3.3	3.6	4.8	4.3	3.9	3.8	0.9
Alcohol drinker status: Never	5.3	6.3	10.1	2.4	2.3	2.6	2.8	2.2	2.6	2.0	3.2	2.5
Lung FEV1/FVC ratio	5.1	25.9	47.9	2.3	-5.8	-5.3	-6.2	-6.2	-6.9	-2.3	-5.9	1.1
HbA1C	5.0	5.6	10.8	0.8	-2.8	-1.4	-2.6	-3.2	-3.3	-2.3	-2.4	-0.9
Medication: Aspirin	5.0	6.5	12.3	-1.4	-3.0	-3.1	-2.6	-2.7	-2.6	-1.6	-3.5	-1.6
Alcohol intake frequency.	4.8	11.2	22.0	4.0	3.0	4.7	2.4	2.5	1.6	2.2	4.3	4.0
Serious illness, injury or assault of a close relative in last 2 years	4.7	5.4	9.2	-1.0	-3.0	-2.4	-2.1	-3.0	-2.4	-2.6	-2.2	-1.6
Impedance of leg (left)	4.5	22.0	41.5	-1.0	6.0	4.6	4.8	6.4	5.5	3.9	5.3	-0.7
Rheumatoid Arthritis	4.4	6.1	10.1	1.7	2.7	2.3	3.1	2.4	3.2	2.7	2.0	1.7
Other serious medical condition/disability diagnosed by doctor	4.3	5.6	8.2	-2.4	-2.2	-2.9	-2.4	-1.7	-2.1	-2.1	-2.5	-2.8
Impedance of leg (right)	4.3	20.6	36.7	-0.4	5.7	4.9	4.8	6.1	5.2	3.8	5.1	-0.7
Medication: Aspirin	4.3	5.7	11.0	-0.9	-2.9	-2.7	-2.3	-2.7	-2.6	-1.5	-3.3	-1.4
Illnesses of mother	4.2	5.2	9.4	-1.5	2.7	1.6	2.8	3.1	3.0	2.1	2.1	0.1
Worry too long after embarrassment	4.2	7.0	14.7	3.8	1.4	3.0	2.9	2.0	1.0	2.8	1.9	3.6
Illnesses of father: Heart disease	4.2	5.8	8.0	-1.9	-2.5	-2.8	-2.5	-2.6	-2.3	-2.7	-2.4	-1.8
Alcohol intake versus 10 years previously	4.1	6.1	12.8	2.1	2.4	3.6	2.2	2.7	2.0	2.3	2.8	1.7
Hayfever/allergic rhinitis (self-reported)	3.7	4.9	13.3	-1.4	3.0	1.4	2.2	3.6	2.6	1.7	1.8	-0.3
Pulse wave peak to peak time	3.7	4.3	8.1	0.6	2.9	1.9	2.0	2.3	2.5	2.2	1.9	1.6
Length of working week for main job	3.6	4.0	7.4	1.8	1.3	2.5	2.7	1.0	1.6	0.9	2.6	2.5
Lupus	3.5	5.3	9.9	1.0	2.9	2.7	1.9	3.1	2.6	2.2	2.2	0.7
Height	3.5	67.7	132.2	-0.3	9.7	7.5	7.9	11.5	11.4	8.3	7.7	-2.2
Medication: Lisinopril	3.4	4.4	8.4	-1.1	-2.4	-1.9	-2.3	-2.3	-2.2	-1.8	-2.9	-1.5
Average weekly fortified wine intake	3.3	3.9	6.5	0.4	2.2	2.2	2.1	2.3	2.4	1.4	2.5	1.1
Medication: Paracetamol	3.3	5.2	13.0	3.6	1.3	2.9	1.7	2.0	1.1	1.6	1.7	3.1
Heel bone mineral density (BMD) T-score, automated (right)	3.2	7.3	10.7	1.2	2.5	3.0	3.1	3.0	3.3	2.0	3.1	2.4
Impedance of whole body	3.2	16.3	32.3	-2.7	5.5	3.6	3.7	5.7	4.6	2.5	4.5	-1.8
High blood pressure (mother)	3.1	4.3	9.1	-0.2	-2.5	-2.2	-2.3	-3.0	-2.2	-2.3	-1.7	0.1
Neuroticism score	3.1	6.4	16.3	3.2	1.7	2.7	2.2	2.4	1.2	1.8	2.5	4.0
Tinnitus: Yes, now most or all of the time	3.1	3.6	6.2	-2.1	-1.1	-1.4	-1.9	-0.8	-2.0	-2.0	-2.5	-2.5
Type 2 Diabetes (T2D) (2018)	3.0	5.5	22.9	4.8	-1.8	1.5	1.1	-2.3	-1.9	-0.3	0.2	3.3
Illnesses of father: None of the above (group 1)	3.0	3.7	6.4	1.5	2.0	2.2	1.6	2.4	2.2	2.5	1.2	1.3
Irritable Bowel Disease (IBD)	2.9	6.9	13.4	-0.1	3.0	2.4	2.7	3.7	3.3	2.4	3.1	-0.2
Financial situation satisfaction	2.9	3.6	12.8	2.9	0.7	2.0	1.7	0.0	0.7	0.3	1.9	3.6
Crohns Disease (2012)	2.7	4.3	7.1	1.1	2.0	1.7	1.8	2.6	2.7	2.7	2.4	0.6
Impedance of arm (left)	2.7	12.7	24.7	-3.7	5.0	2.7	2.5	5.0	3.9	1.4	4.0	-2.3
Pulse wave Arterial Stiffness index	2.6	3.0	6.3	-0.3	-2.5	-1.6	-1.6	-1.9	-2.0	-1.6	-1.7	-1.6
Medication: Co-codamol	2.5	2.9	7.0	0.5	2.4	2.6	1.5	1.9	1.0	0.8	2.3	0.8
Fluid intelligence score	2.5	5.3	13.0	0.6	-2.6	-2.0	-2.0	-3.6	-2.6	-2.3	-2.6	-0.1
Breastfed as a baby	2.4	3.0	13.0	-2.2	-1.1	-1.7	-1.3	-0.6	-0.4	-1.2	-1.1	-3.6
Relative age of first facial hair	2.3	4.7	8.4	-2.0	-1.9	-2.9	-2.6	-2.1	-2.2	-1.6	-2.5	-1.2
Hand grip strength (right)	2.3	6.3	22.8	0.7	2.4	0.6	1.6	3.1	3.7	4.8	1.0	0.9
Number of full brothers	2.3	2.9	13.2	3.6	0.3	1.5	1.3	0.1	0.4	1.8	1.0	2.1
Pulse rate, automated reading	2.3	7.5	14.7	-0.3	-3.2	-2.2	-3.1	-3.3	-3.8	-3.1	-2.6	-1.1
Diabetes diagnosed by doctor	2.3	3.7	12.4	3.5	-1.2	1.6	1.2	-1.8	-1.3	-0.8	0.4	3.2
Verbal and Numeric Reasoning (VNR)	2.2	5.3	11.3	0.1	-2.5	-2.2	-2.3	-3.4	-2.2	-2.7	-2.7	-0.4
Cardiovascular Disease	2.2	7.4	15.7	1.3	-4.0	-2.0	-2.5	-3.5	-3.5	-1.9	-3.1	-0.8
Standing height	2.2	21.7	45.0	0.1	5.0	3.8	4.3	6.4	6.7	5.6	4.0	-2.2
Medication: Amlodipine	2.2	3.1	6.7	-0.9	-2.6	-2.5	-1.2	-2.5	-1.3	-1.3	-1.8	-0.4
Suffer from ‘nerves’	2.2	3.5	7.4	1.2	1.8	2.0	2.1	2.7	1.4	1.6	1.6	2.0
Illness, injury, bereavement, stress in last 2 years	2.2	2.7	5.9	-0.4	2.0	1.3	1.2	2.4	2.0	2.2	1.5	0.2
Qualifications: nursing, teaching	2.2	3.3	6.3	-1.8	-1.3	-1.6	-2.0	-1.9	-1.2	-2.5	-1.1	-2.5
Supplements: Fish oil (including cod liver oil)	2.2	2.8	4.5	-1.2	-1.4	-1.7	-2.1	-1.7	-2.1	-1.8	-1.9	-0.7
Heel T-Score	2.1	17.1	27.0	0.7	4.7	4.0	4.2	4.7	5.2	2.9	5.1	3.8
High blood pressure	2.1	6.0	14.9	1.1	-3.9	-2.1	-1.6	-3.3	-3.0	-2.1	-2.5	0.1
Hair/balding pattern: Pattern 2	2.1	2.7	6.4	-2.5	-1.9	-1.7	-1.0	-1.0	-1.2	-2.1	-1.0	-1.8
Medication: Blood pressure	2.1	3.8	7.4	-0.0	-2.7	-2.2	-1.4	-2.7	-2.0	-1.6	-2.4	-0.5
Number of full sisters	2.1	2.6	8.6	2.9	0.1	2.7	1.0	-0.2	-0.2	0.3	0.9	2.4
Hypertension (Self-reported)	2.1	5.7	13.8	1.0	-3.7	-2.2	-1.6	-3.2	-3.0	-2.0	-2.5	0.1
Wears glasses or contact lenses	2.1	2.4	4.8	-1.7	-1.3	-2.2	-1.3	-1.5	-1.1	-1.5	-1.6	-1.5
Blood White Count	2.0	14.9	31.6	1.6	-4.9	-2.8	-3.3	-5.6	-5.3	-3.9	-3.7	1.0
Medication: Metformin	2.0	2.9	7.3	2.7	-1.4	1.1	0.4	-1.9	-1.8	-1.6	0.1	2.4
Multivitamins +/- minerals	2.0	2.6	4.5	-0.5	-2.1	-1.6	-1.4	-2.1	-1.7	-1.8	-1.7	0.4
Average weekly champagne plus white wine intake	2.0	2.8	5.0	1.3	1.5	1.6	2.2	0.8	2.1	2.0	1.4	1.7
Bipolar Disorder (2011)	1.9	1.8	4.0	-1.5	-0.9	-2.0	-2.0	-1.1	-0.6	-0.8	-1.1	-1.4
Vitamin and mineral supplements	1.9	2.5	5.2	0.4	2.3	1.6	1.7	1.6	1.6	1.4	2.2	0.1
Diabetes (self-reported)	1.9	2.9	10.1	3.2	-1.1	1.1	0.7	-1.8	-1.1	-0.4	0.0	2.9
Impedance of arm (right)	1.9	8.8	17.6	-3.5	4.0	2.2	1.6	4.2	3.1	0.8	3.1	-2.5
Worrier / anxious feelings	1.9	3.6	6.6	2.0	1.8	2.6	1.7	2.4	1.1	0.8	2.0	2.2
Asthma	1.9	3.8	5.7	1.1	1.6	2.0	2.4	2.3	2.1	1.7	1.9	2.2
Medication: Paracetamol	1.9	3.2	8.6	2.9	1.1	2.4	1.0	1.8	0.6	1.2	1.3	2.3
Leg fat percentage (right)	1.9	6.9	20.4	4.3	0.7	4.5	2.8	1.0	0.6	0.7	2.1	3.0
Medication: Seretide 50 evohaler	1.9	2.2	4.4	-0.2	-2.1	-1.8	-1.9	-1.7	-1.3	-0.7	-1.9	-0.5
Bipolar Disorder (2018)	1.8	2.8	6.6	-2.5	-0.9	-2.6	-2.0	-0.5	-0.6	-0.6	-2.0	-1.7
Alzheimer’s Disease (in father)	1.8	2.0	6.1	-0.1	-1.2	-1.4	-2.5	-1.2	-1.8	-0.4	-1.5	-1.2
Smoking Status	1.8	4.3	7.3	-0.7	-2.6	-2.0	-2.6	-1.7	-2.2	-2.0	-2.7	-1.3
Had menopause	1.8	2.2	5.4	0.1	-1.2	-1.6	-1.6	-1.9	-1.9	-2.3	-0.9	0.1
Age at last live birth	1.8	2.7	5.4	0.2	1.8	1.7	2.3	2.3	1.4	1.9	1.4	0.1
Sensitivity / hurt feelings	1.7	2.9	6.9	2.6	1.4	1.8	1.3	1.4	0.3	1.6	1.0	2.6
Exposure to tobacco smoke outside home	1.7	2.2	5.3	1.3	1.1	1.4	2.3	0.9	1.9	1.5	1.6	0.9
Asthma (self-reported)	1.7	3.3	4.9	0.9	1.5	1.8	2.2	2.2	2.1	1.7	1.5	2.1
Leg fat percentage (left)	1.7	6.0	17.1	3.9	0.7	4.1	2.7	1.0	0.6	0.6	2.0	2.9
Vascular/heart problems diagnosed by doctor	1.7	4.6	12.5	-1.0	3.5	2.0	1.4	2.9	2.5	1.5	2.2	-0.1
Coronary Artery Disease (CAD)	1.6	1.9	4.5	0.6	-1.5	-1.7	-2.1	-1.1	-1.9	-0.2	-1.4	-0.0
Frequency of unenthusiasm / disinterest in last 2 weeks	1.6	2.1	4.5	1.9	1.4	1.0	0.2	1.8	0.7	1.7	1.1	2.1
Hip circumference	1.6	6.7	17.6	4.1	1.6	4.2	2.4	1.7	1.5	1.7	2.2	2.1
Medication for cholesterol, blood pressure or diabetes	1.6	2.6	5.0	-0.3	2.2	1.3	1.3	2.0	1.8	1.5	2.1	0.9
Age started oral contraceptive pill	1.6	2.0	4.7	-0.2	2.2	1.2	1.4	2.1	1.8	0.9	1.4	0.0
Trunk fat percentage	1.5	6.0	17.8	2.7	1.6	4.2	3.0	1.9	1.4	0.9	2.5	2.1
Age when periods started (menarche)	1.5	3.7	7.5	-2.3	2.6	-0.6	-0.2	2.7	2.2	1.9	0.8	-2.0
Past tobacco smoking	1.5	2.7	5.7	1.7	1.3	1.9	1.7	0.3	1.0	1.4	2.0	2.4
Fasting Glucose	1.4	1.7	6.9	2.6	-0.1	1.5	0.6	-1.1	-1.4	-0.5	0.5	1.4
Blood Red Count	1.4	13.6	27.7	2.9	-5.2	-2.7	-3.4	-5.3	-4.1	-2.2	-3.4	2.6
Neuroticism	1.4	3.5	9.9	2.0	1.0	2.0	1.8	2.0	0.7	1.0	2.0	3.2
Hand grip strength (left)	1.4	3.8	16.8	0.0	1.8	-0.1	0.8	2.2	2.9	4.1	0.0	-0.1
Frequency of depressed mood in last 2 weeks	1.4	1.9	4.3	1.4	1.4	1.6	1.0	1.4	1.0	1.4	0.8	2.1
Heel bone mineral density (BMD) T-score, automated (left)	1.4	3.1	5.5	1.1	1.6	1.9	1.8	1.8	1.7	0.8	2.3	2.3
Nervous feelings	1.4	2.6	5.6	1.0	1.5	2.2	1.8	2.4	0.9	1.1	1.4	1.7
Medication: Simvastatin	1.4	2.1	3.8	-0.4	-2.0	-1.3	-1.3	-1.9	-1.6	-1.5	-1.7	-0.6
Frequency of tiredness / lethargy in last 2 weeks	1.4	2.2	6.4	1.6	1.4	2.5	1.0	1.5	0.4	-0.0	1.6	1.8
Headache pain in last month	1.4	2.4	7.6	2.8	0.8	2.2	1.0	1.1	0.2	1.1	1.1	1.8
Chronic bronchitis/emphysema (mother)	1.4	1.6	5.1	2.3	0.5	1.5	1.0	0.3	0.9	1.3	0.5	1.7
Body fat percentage	1.4	5.5	16.6	3.4	1.0	4.1	2.7	1.1	0.9	0.6	2.0	2.5
Mean time to correctly identify matches	1.4	2.6	5.4	-1.1	-1.7	-2.1	-1.5	-2.0	-1.4	-2.3	-1.1	-0.8
Guilty feelings	1.4	2.1	6.5	0.8	1.6	1.4	1.4	2.6	1.0	1.6	1.1	0.7
Prostate Cancer	1.3	1.8	3.9	-0.1	-1.9	-1.7	0.2	-2.0	-1.0	-0.8	-1.5	1.3
Trunk fat mass	1.3	5.6	16.5	3.2	1.2	4.1	2.8	1.8	1.5	1.2	2.1	2.0
Mouth/teeth dental problems: Dentures	1.3	2.2	4.7	-0.1	1.1	1.6	2.2	1.8	2.2	1.3	1.4	0.1
Seen a psychiatrist for nerves, anxiety, tension or depression	1.3	1.7	7.6	-2.8	0.1	-1.0	-1.2	1.0	0.7	-1.0	-0.5	-1.6
Leg fat mass (right)	1.3	5.0	18.0	4.2	0.0	3.7	2.1	0.6	0.5	0.8	1.3	2.5
Diastolic blood pressure, automated reading	1.3	4.0	8.6	1.7	-2.9	-2.1	-1.3	-2.9	-2.1	-0.7	-1.9	1.3
Primary Biliary Cirrhosis	1.2	1.7	4.1	0.3	2.0	1.5	1.1	1.4	1.2	0.9	1.7	0.7
Taking other prescription medications	1.2	1.8	5.6	2.4	-0.3	1.9	1.9	1.0	0.3	1.0	0.3	1.2
Financial difficulties in last 2 years	1.2	1.6	6.3	2.5	-0.0	1.3	1.1	-0.1	0.3	1.1	0.6	1.9
Forced vital capacity (FVC), Best measure	1.2	4.5	9.3	-2.6	1.9	-0.0	0.9	2.8	3.1	2.2	0.7	-2.7
Whole body fat mass	1.2	4.9	14.0	3.7	0.5	3.6	2.4	1.0	1.0	1.0	1.5	2.3
Smoking status: Previous	1.2	1.8	4.3	-1.4	-1.0	-2.1	-1.5	-0.4	-0.6	-0.9	-1.5	-1.6
Medication for cholesterol	1.2	1.9	5.0	-1.5	2.2	0.6	0.6	1.9	1.7	1.0	1.0	-0.6
Leg fat mass (left)	1.2	4.8	17.0	4.1	-0.0	3.5	2.2	0.6	0.6	0.8	1.2	2.5
Alzheimer’s Disease (in mother)	1.1	1.3	4.7	0.8	-0.9	-0.2	-1.6	-0.6	-2.2	-0.3	-1.3	-1.0
Type 2 Diabetes (T2D) (2012)	1.1	1.3	4.1	2.0	-1.3	0.1	0.2	-1.7	-1.1	-0.9	-0.0	1.0
Lung FVC	1.1	5.8	16.5	-4.1	-1.6	-2.9	-1.6	-1.0	-0.9	-2.0	-2.1	-3.4
Body mass index (BMI)	1.1	4.8	16.8	4.1	-2.1	1.4	-0.1	-2.2	-2.0	-1.2	-0.7	3.0
Forced vital capacity (FVC)	1.1	4.3	14.2	-3.1	1.0	-1.0	0.2	2.1	2.3	1.8	-0.2	-3.8
Medication: Lansoprazole	1.1	1.3	5.8	2.4	-0.6	1.5	0.9	-0.2	-1.0	0.3	-0.6	0.9
Comparative height size at age 10	1.1	6.3	11.6	-0.4	3.0	2.9	2.2	3.4	3.4	1.4	2.5	-1.6
Mouth/teeth dental problems: Mouth ulcers	1.1	1.8	4.0	0.1	1.9	1.7	0.9	2.0	1.2	0.8	1.7	-0.0
Illnesses of father: High blood pressure	1.1	1.3	3.0	-1.0	-1.4	-1.7	-1.0	-1.6	-0.6	-1.5	-0.1	0.2
Intelligence (Savage-Jansen 2018)	1.0	3.1	5.8	1.2	-2.4	-1.6	-1.7	-2.1	-2.4	-1.3	-2.0	0.3
Ulcerative Colitis (UC)	1.0	1.9	3.2	-1.6	1.8	0.7	1.0	1.7	1.4	0.5	1.7	-1.4
Supplements: Zinc	1.0	1.1	5.0	1.9	-0.2	0.8	0.0	-0.1	-0.7	0.0	0.3	2.2
Mouth/teeth dental problems	1.0	1.5	3.3	0.6	-1.3	-1.6	-1.3	-1.8	-1.4	-0.1	-1.3	0.2
Time employed in main current job	1.0	1.1	3.3	-1.8	-0.8	-1.8	-0.5	-0.8	0.2	-0.8	-1.1	-0.4
Lung cancer (father)	1.0	1.2	4.2	1.1	0.4	2.1	0.9	-0.5	-1.0	-1.0	1.2	0.5
Illnesses of siblings: Diabetes	1.0	1.2	3.7	1.9	-1.0	0.4	-0.0	-1.4	-1.0	-1.0	0.4	1.3
Medication: Blood pressure	1.0	1.8	4.0	1.3	-2.0	-0.5	-0.3	-1.8	-1.9	-0.9	-0.9	1.4
Ever smoked	1.0	1.7	5.3	-1.3	-1.1	-1.2	-1.3	0.2	-0.4	-1.2	-1.7	-2.3
Bipolar Disorder or Schizophrenia	0.9	2.1	4.8	-2.2	-0.9	-1.8	-1.3	0.3	-0.2	-0.1	-1.8	-2.2
Worry (Nagel 2018)	0.9	2.0	4.4	1.4	0.7	2.0	1.6	1.5	0.3	0.4	1.3	2.1
Hearing difficulty/problems: Yes	0.9	1.4	4.2	-0.8	-0.4	-1.3	-1.8	-0.4	-0.4	-0.3	-1.3	-2.0
Exposure to tobacco smoke at home	0.9	1.0	2.5	0.9	1.5	1.2	0.7	1.1	0.2	-0.1	1.6	0.5
Peak expiratory flow (PEF)	0.9	2.0	5.6	-0.9	-0.5	-2.4	-1.5	-0.0	0.4	2.0	-1.8	-1.5
High blood pressure (siblings)	0.9	1.3	3.2	0.1	-1.8	-1.5	-0.8	-1.6	-1.1	-0.7	-1.0	0.7
Neck or shoulder pain in last month	0.9	1.2	3.6	0.6	-1.9	-1.2	0.1	-1.6	-0.9	-0.6	-1.3	0.3
Ever depressed for a whole week	0.9	1.1	2.6	-0.0	-0.8	-0.3	-0.9	-1.5	-1.3	-1.6	-0.6	1.2
Body Mass Index (BMI) (2010)	0.8	1.1	2.2	1.2	-1.2	0.3	-1.3	-1.5	-1.3	-1.2	-0.5	0.1
Blood Eosinophil Count	0.8	6.3	17.0	2.0	-2.7	-1.2	-0.9	-3.7	-2.3	-2.5	-1.1	4.1
BMI	0.8	4.9	15.4	3.9	-2.4	0.4	-1.1	-2.5	-2.3	-0.9	-1.5	2.6
Chronotype (morning person)	0.8	1.8	5.9	1.7	1.3	2.4	1.5	0.3	0.7	0.4	1.5	0.7
Number of treatments/medications taken	0.8	1.5	3.7	1.9	-1.6	-0.1	-0.6	-0.6	-1.5	-0.5	-1.3	1.4
Medication for hormone replacement therapy	0.8	0.9	1.9	1.0	-1.4	-1.1	-0.6	-1.3	-0.8	-0.9	0.1	-0.0
Hayfever, allergic rhinitis or eczema	0.8	1.8	7.8	-2.8	-0.7	-2.0	-0.8	-0.7	-0.3	-1.2	-0.9	-0.7
Heart attack	0.8	1.0	3.5	-0.7	-0.6	-1.9	-1.1	-0.8	-0.3	0.7	-1.2	-0.8
Illnesses of siblings	0.8	1.1	3.1	-1.5	1.4	0.3	-0.0	1.1	1.0	-0.0	0.2	-1.8
Weight	0.8	4.0	15.6	4.0	0.2	3.0	1.8	0.8	0.9	1.3	1.1	1.8
Number of live births	0.8	1.1	2.3	0.8	1.5	0.7	0.6	1.3	1.1	1.0	1.4	0.4
Medication: Cholesterol lowering	0.8	1.2	2.3	-0.4	-1.3	-1.0	-1.0	-1.5	-1.3	-1.5	-1.0	-0.6
Wheeze or whistling in the chest in last year	0.8	1.4	3.3	0.9	0.8	1.8	1.3	1.4	1.1	0.2	1.0	1.2
Medication: Ibuprofen	0.8	0.9	4.8	2.2	-0.1	0.6	0.5	0.3	-0.4	0.3	-0.2	1.6
Qualifications: NVQ or HND or HNC or equivalent	0.8	1.0	2.5	0.5	0.0	1.1	1.6	0.8	1.2	1.0	1.2	0.7
Average weekly red wine intake	0.8	1.1	5.5	2.4	0.2	0.4	0.0	0.1	-0.2	0.7	0.3	1.9
Medication: Gliclazide	0.8	0.9	2.9	1.4	-0.8	0.3	-0.0	-0.4	-1.1	-0.1	-0.8	1.7
Arm fat mass (left)	0.8	3.3	12.5	3.5	-0.2	2.9	1.4	-0.0	0.0	0.0	0.8	2.3
Myopia	0.8	1.2	3.1	1.4	-0.9	-0.1	-0.2	-1.8	-1.7	-0.9	-0.2	1.2
Cholesterol lowering medication	0.8	1.1	2.1	0.9	-1.4	-0.4	-0.7	-1.4	-1.4	-0.8	-1.4	0.4
Heart attack/myocardial infarction (self-reported)	0.8	1.0	3.9	-1.0	-0.5	-2.0	-1.2	-0.8	-0.3	0.5	-1.1	-0.7
Ulcerative Colitis	0.7	1.0	2.3	-0.0	1.5	0.4	0.7	1.1	1.2	1.1	1.3	0.1
Maternal smoking around birth	0.7	1.1	5.0	2.2	-1.6	0.2	-0.1	-0.9	-0.8	0.3	-0.4	0.4
Medication: Levothyroxine sodium	0.7	1.2	3.8	-1.3	-0.7	-0.7	-1.3	-0.7	-1.3	-1.9	-0.5	-0.6
Waist circumference	0.7	2.4	10.4	3.2	-1.1	2.2	1.2	-0.6	-0.5	-0.2	-0.2	1.7
Forced expiratory volume in 1-second (FEV1)	0.7	2.3	8.1	-2.1	-0.1	-1.7	-0.8	0.8	1.0	1.5	-1.0	-2.9
Arm fat mass (right)	0.7	3.0	13.2	3.6	-0.7	2.6	1.1	-0.3	-0.3	-0.1	0.4	2.2
Birth weight	0.7	1.5	3.9	-1.0	1.5	0.2	-0.1	2.0	1.5	1.5	0.6	-1.0
Arm fat percentage (left)	0.7	2.9	8.4	2.9	-0.2	2.8	1.2	-0.3	-0.5	-0.7	0.9	2.5
Osteoporosis (self-reported)	0.7	0.9	5.1	-2.3	-0.1	-0.9	-0.5	-0.2	-0.2	-0.8	-0.5	-0.9
High cholesterol (Self-reported)	0.7	1.2	3.1	0.5	-1.3	-0.4	-1.1	-1.0	-1.8	-1.0	-1.3	-0.7
Depression (Nagel 2018)	0.6	0.9	3.2	1.0	0.7	-0.0	-0.1	1.1	0.8	1.3	0.1	1.8
Blood Platelet Count	0.6	6.8	24.0	-2.2	-2.3	-0.3	-1.7	-1.8	-3.7	-4.9	-1.2	-2.4
Average weekly spirits intake	0.6	0.8	2.8	-1.7	0.6	0.3	0.3	0.9	0.7	-0.3	-0.4	-1.4
Eye problems/disorders: Diabetes related eye disease	0.6	0.6	1.1	1.0	0.0	0.9	0.3	-0.7	-0.6	-1.0	0.9	1.0
Severe depression (siblings)	0.6	0.7	1.8	0.6	0.7	0.6	1.3	0.8	1.0	0.4	0.5	1.1
Pack years adult smoking proportion	0.6	0.9	3.6	1.9	-0.4	0.8	-0.2	-1.4	-0.7	-0.8	0.1	0.7
Townsend deprivation index at recruitment	0.6	0.8	1.8	1.2	-1.1	0.2	-0.9	-0.8	-1.3	-0.7	-0.7	0.0
Current tobacco smoking	0.6	1.0	2.9	1.1	-1.3	0.1	-0.9	-0.9	-1.7	-0.9	-1.0	-0.2
Qualifications: CSEs or equivalent	0.6	0.8	3.0	1.7	0.5	0.9	0.1	0.6	0.0	1.2	0.6	0.9
Number of incorrect matches in round	0.6	1.1	2.5	0.4	-1.1	-0.1	0.1	-1.4	-1.6	-1.5	-0.9	0.8
Frequency of tenseness / restlessness in last 2 weeks	0.6	1.0	3.7	1.9	-0.8	0.4	0.1	-0.5	-0.9	-0.5	-0.7	1.5
Pain all over the body in last month	0.6	0.7	1.8	1.4	0.6	1.0	0.9	0.8	0.5	0.6	0.7	0.6
Arm fat percentage (right)	0.6	2.5	7.8	2.8	-0.8	2.4	0.6	-0.8	-0.9	-1.1	0.3	2.2
Hair/balding pattern: Pattern 3	0.6	0.9	3.0	-0.4	1.7	0.5	-0.3	1.3	1.1	0.8	1.2	0.0
Seen doctor (GP) for nerves, anxiety, tension or depression	0.6	1.0	3.2	1.4	0.7	0.6	0.4	1.2	0.0	1.0	0.4	1.8
Hair/balding pattern: Pattern 4	0.6	1.4	4.8	2.2	-0.2	0.3	1.0	0.2	1.1	1.5	-0.7	1.5
Arm fat-free mass (right)	0.6	3.2	14.5	3.8	-0.5	1.2	1.4	0.2	1.3	2.4	-0.1	1.7
Medication for pain relief, constipation, heartburn	0.6	1.0	3.7	-1.9	1.3	-0.2	0.3	0.6	1.2	0.4	0.9	-0.8
Arm predicted mass (right)	0.6	3.3	14.9	3.9	-0.4	1.4	1.5	0.3	1.3	2.4	-0.0	1.7
Mood swings	0.6	1.0	3.3	1.8	-0.4	1.0	-0.3	0.9	-0.0	0.6	0.4	1.8
Long-standing illness, disability or infirmity	0.6	0.9	2.2	1.4	-1.2	0.0	-0.4	-0.9	-1.2	-0.2	-1.5	0.1
Breast cancer (self-reported)	0.6	0.7	2.5	-0.1	-0.6	-1.0	-0.9	-1.6	-0.9	-0.6	-0.6	0.5
Number of self-reported non-cancer illnesses	0.6	1.0	5.2	2.3	-1.3	0.5	0.8	-0.4	-0.7	0.0	-0.5	0.9
Hearing aid user	0.6	0.6	2.5	-0.8	-0.2	-1.0	-1.6	-0.0	0.2	0.4	-0.7	-0.9
Medication: Bendroflumethiazide	0.6	0.9	2.1	1.0	-1.4	-1.0	-0.6	-0.8	-1.3	-0.3	-1.0	0.0
Arm fat-free mass (left)	0.6	2.8	15.8	4.0	-1.0	1.2	1.0	-0.3	0.8	1.8	-0.4	1.5
Medication: Omeprazole (e.g. Zanprol)	0.6	0.7	2.2	0.9	0.5	1.5	0.8	1.0	-0.3	-0.4	0.8	-0.2
Pain experienced in last month	0.6	1.0	5.1	-2.3	-0.3	-1.1	-0.7	-0.5	-0.0	-0.6	-0.6	-1.0
Deep venous thrombosis (DVT) (self-reported)	0.6	0.7	2.5	1.5	-0.5	-0.4	0.1	-0.1	0.2	1.6	-0.8	0.8
Pack years of smoking	0.6	0.8	3.0	1.7	-0.5	0.6	-0.1	-1.5	-0.6	-0.9	0.0	0.5
Neuroticism (Nagel 2018)	0.5	1.2	4.6	1.1	0.4	0.7	0.3	1.6	0.2	0.6	1.0	2.1
Schizophrenia vs Biploar Disorder	0.5	0.7	3.9	2.0	-0.8	0.2	0.3	-0.2	-0.5	0.6	-0.2	0.8
Alzheimer’s Disease (including proxy)	0.5	0.8	2.5	0.6	-0.5	-0.2	-1.3	-0.3	-1.6	0.2	-0.9	-1.0
Major Depression (MDD)	0.5	0.6	1.7	-0.1	0.5	0.4	0.7	0.9	1.1	0.3	0.7	1.3
Reaction Time	0.5	1.0	2.8	0.2	-1.0	-1.0	-1.1	-1.4	-1.1	-1.7	-0.4	0.2
Neuroticism (2016)	0.5	0.8	2.7	1.6	-0.2	0.4	0.1	0.8	-0.0	1.0	0.3	1.5
Triglycerides	0.5	0.9	1.4	-0.6	-0.8	-1.0	-1.1	-1.1	-0.7	-1.2	-1.0	0.2
Waist Hip Ratio (WHR)	0.5	2.3	4.8	-1.6	-1.7	-1.1	-0.6	-1.3	-1.0	-1.5	-2.2	-1.8
Allergy or Eczema	0.5	1.4	9.7	-3.1	0.5	-0.9	0.3	0.6	0.6	-0.8	0.3	-0.4
Ever used hormone-replacement therapy (HRT)	0.5	0.7	2.5	0.6	-0.8	-0.7	-0.2	-1.0	-0.8	-1.6	-0.2	0.4
Serious illness, injury or assault to yourself	0.5	0.6	2.0	0.3	-0.4	-0.4	-0.4	-1.4	-0.6	-1.3	-0.6	0.3
Ever unenthusiastic/disinterested for a whole week	0.5	0.6	1.9	1.2	0.4	1.0	0.8	0.2	0.1	0.3	0.7	1.4
Medication: Ibuprofen (e.g. Nurofen)	0.5	0.6	2.5	1.6	0.0	0.1	-0.1	0.3	-0.1	0.7	-0.4	1.4
Forced expiratory volume in 1-second (FEV1), Best measure	0.5	1.7	4.1	-2.0	0.4	-1.2	-0.4	1.1	1.3	1.4	-0.6	-2.0
Pulse wave reflection index	0.5	0.6	1.4	-0.6	-0.9	-0.3	-0.5	-0.5	-0.7	-1.2	-0.7	-1.0
Blood clot in the leg (DVT)	0.5	0.6	2.1	1.5	-0.4	-0.3	0.1	0.1	0.3	1.4	-0.6	0.9
Medication: Ventolin 100micrograms inhaler	0.5	0.6	4.0	0.6	-0.0	0.5	1.0	0.2	-0.1	-0.0	0.3	2.0
Comparative body size at age 10	0.5	1.4	3.3	-1.8	-1.0	-0.6	-0.9	-0.5	-0.6	-1.6	-1.1	-1.7
Health satisfaction	0.5	0.6	2.0	0.4	-0.6	0.4	-0.4	-1.1	-1.0	-1.4	0.1	0.8
Eye problems/disorders: None of the above	0.5	0.6	1.5	-0.9	-1.1	-0.2	0.4	-1.0	0.1	-1.2	-0.3	-0.9
Mouth/teeth dental problems: Loose teeth	0.5	0.6	3.6	-0.4	-0.2	0.4	-0.3	-0.1	-1.2	-1.9	-0.3	-0.3
Emphysema/chronic bronchitis	0.5	0.6	1.7	-0.3	-0.5	-0.2	-1.3	-0.7	-0.6	-1.1	-0.9	-0.4
Medication: Omeprazole	0.5	0.6	1.4	0.7	0.7	1.2	0.5	0.9	-0.3	-0.7	1.1	0.0
Had major operations	0.5	0.6	1.5	0.6	0.9	0.8	1.2	0.3	1.1	0.6	0.4	0.4
Commuting to job workplace: Car/motor vehicle	0.5	0.5	2.4	-1.6	0.3	-0.2	0.2	0.1	0.8	-0.5	0.4	-1.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.5	0.5	1.2	1.1	-1.0	0.9	0.6	-0.2	-0.9	-0.8	-0.3	0.2
Forced expiratory volume in 1-second (FEV1), predicted	0.5	1.0	4.4	-2.1	0.2	-0.7	-0.8	0.6	0.3	-0.3	0.1	-1.6
Ever had bowel cancer screening	0.5	0.6	4.0	-0.9	-0.2	-0.5	-0.0	0.3	0.4	-0.4	-0.5	-2.0
Back pain experienced in last month	0.5	0.7	1.6	1.2	0.1	1.3	0.6	0.3	0.1	-0.7	1.2	0.6
Mineral and other dietary supplements	0.5	0.7	1.4	1.1	0.4	0.6	0.9	0.6	1.0	0.8	1.2	0.3
Smoking status: Current	0.5	0.8	2.3	0.6	-1.2	-0.0	-0.9	-0.8	-1.5	-1.0	-1.0	-0.4
Miserableness	0.5	0.8	4.4	-0.1	0.7	0.4	-0.3	2.1	0.8	0.4	0.9	0.8
Ever taken oral contraceptive pill	0.5	0.6	1.7	0.8	1.3	0.1	0.7	0.6	0.5	1.1	0.5	0.3
Medication: Atorvastatin	0.5	0.6	1.6	1.2	0.4	1.3	0.8	0.4	-0.2	0.4	0.5	1.2
Unable to work because of sickness or disability	0.5	0.7	2.5	1.6	0.2	1.1	-0.1	0.7	0.1	0.9	-0.0	0.9
Arm predicted mass (left)	0.5	2.7	15.0	3.9	-1.0	1.1	1.0	-0.3	0.8	1.7	-0.4	1.5
Breast Cancer	0.4	1.0	3.0	-1.7	0.6	-0.2	0.5	1.3	0.9	-0.1	0.3	-1.7
Ovarian Cancer	0.4	0.5	1.5	-0.6	-0.8	-0.7	-0.9	0.2	0.1	0.0	-0.7	-1.2
HDL Cholesterol	0.4	0.7	1.7	0.0	1.0	0.5	0.8	1.1	1.1	1.3	0.7	-0.5
Schizophrenia (2014)	0.4	0.8	2.4	0.1	-1.1	-1.2	-1.1	-0.3	-0.3	0.7	-1.5	-0.6
Systolic Blood Pressure	0.4	1.8	3.7	1.0	-1.8	-1.9	0.1	-1.9	-0.4	0.6	-1.7	0.9
Hypothyroidism (self reported)	0.4	0.9	2.9	0.8	0.8	0.9	1.0	0.9	0.4	0.1	0.9	1.7
Respiratory disease	0.4	0.8	1.5	-0.4	0.6	1.1	1.2	1.1	1.2	0.0	1.0	0.6
Hair Pigment	0.4	11.1	17.4	1.4	3.4	3.4	3.9	4.1	4.2	3.7	3.1	1.4
Diabetes (mother)	0.4	0.5	1.5	0.4	-0.3	-0.1	-0.6	-0.9	-0.8	-1.2	0.4	0.7
Fed-up feelings	0.4	0.7	3.6	0.7	-0.0	0.7	-0.3	0.9	0.0	-0.2	0.7	1.9
Stomach or abdominal pain in last month	0.4	0.5	2.1	1.0	0.2	0.4	0.1	0.7	0.5	1.5	-0.7	0.1
Supplements: Glucosamine	0.4	0.5	1.2	-0.8	-0.7	-0.6	-0.6	-0.3	-0.7	-0.4	-1.1	-0.6
Chronic bronchitis/emphysema (father)	0.4	0.4	1.3	0.9	-0.1	0.8	1.1	-0.4	-0.4	-0.4	-0.1	0.9
Pulse rate	0.4	0.6	2.3	0.2	-0.6	-0.2	-0.3	-1.5	-0.8	-1.0	0.0	0.9
Noisy workplace	0.4	0.5	2.3	-1.5	-0.0	-0.3	-0.4	0.5	0.3	-0.2	0.3	-1.3
Depression (self-reported)	0.4	0.4	2.3	-0.6	0.7	0.3	-0.2	1.5	0.5	0.4	-0.0	-0.5
Tense / ‘highly strung’	0.4	0.6	2.0	1.3	-0.1	0.7	0.9	0.3	-0.2	0.1	-0.0	1.4
Ever highly irritable/argumentative for 2 days	0.4	0.5	1.4	0.7	-0.6	0.6	0.1	-1.2	-0.1	-0.7	-0.0	1.2
Mouth/teeth dental problems: Bleeding gums	0.4	0.5	1.2	-0.5	0.9	1.1	0.3	0.8	0.2	-0.8	0.9	-0.5
Age at first live birth	0.4	0.7	3.3	-1.8	0.0	0.0	0.3	1.0	0.4	-0.0	-0.8	-0.8
Eye problems/disorders: Cataract	0.4	0.5	1.7	-0.3	0.2	-1.3	-0.8	0.5	0.3	1.2	-0.6	0.3
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.4	0.5	2.0	-0.7	0.2	0.2	0.7	0.5	0.6	-0.2	0.7	-1.4
Osteoarthritis (self-reported)	0.4	0.5	1.6	-0.4	-0.9	0.3	0.7	-0.2	-0.8	-1.3	-0.4	-0.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.4	0.8	2.6	-1.4	-0.5	-1.0	-0.3	-0.3	0.1	0.0	-1.2	-1.6
Basal metabolic rate	0.4	2.0	10.7	3.3	-0.5	1.4	0.9	0.3	0.9	1.7	-0.1	1.0
Irritability	0.4	0.7	2.3	0.8	-0.9	-0.0	0.2	-1.0	-0.4	-1.0	0.4	1.5
Depressed Affect (Nagel 2018)	0.3	0.6	1.9	-0.4	-0.5	-0.6	-1.4	0.7	-0.1	-0.8	0.1	1.4
Age at First Birth	0.3	0.4	1.8	-1.3	0.4	0.4	-0.1	0.9	0.0	-0.2	0.6	-0.6
Mean Putamen Volume	0.3	0.3	1.3	-0.7	-0.2	-0.1	-0.5	0.2	-0.7	-0.6	1.1	-0.3
Ever had hysterectomy (womb removed)	0.3	0.4	1.0	0.2	0.1	0.8	0.7	0.2	-0.3	-0.9	1.0	-0.3
Diabetes (father)	0.3	0.4	1.7	1.3	-0.3	-0.0	0.1	-0.9	-0.4	-0.2	-0.8	0.6
Relative age voice broke	0.3	0.5	1.2	-0.2	-0.5	-1.1	-0.7	-1.1	-0.8	-0.6	-0.2	0.2
Diverticular disease/diverticulitis (self-reported)	0.3	0.4	1.2	-0.5	0.8	0.3	0.2	1.1	0.7	-0.0	-0.2	-0.7
Had other major operations	0.3	0.4	1.3	-0.1	-0.7	0.4	-0.2	-0.6	-1.2	-0.4	-0.5	-0.5
Trunk fat-free mass	0.3	1.9	8.9	3.0	-0.5	0.8	0.6	0.4	1.2	2.2	-0.3	0.3
Falls in the last year	0.3	0.4	2.0	-0.3	-0.5	-0.3	-0.8	0.2	-0.9	-0.4	-1.4	0.0
Prospective memory result	0.3	0.4	1.2	0.2	0.1	1.1	0.4	1.0	0.3	-0.1	0.7	0.5
Trunk predicted mass	0.3	1.8	8.7	2.9	-0.6	0.7	0.4	0.3	1.1	2.1	-0.4	0.3
Shortness of breath walking on level ground	0.3	0.3	1.5	0.5	0.1	0.3	0.3	-0.5	0.4	-0.8	0.2	1.2
Qualifications: College or University degree	0.3	0.8	3.4	-0.9	-0.4	-0.7	-1.2	-0.3	-0.5	-0.8	0.1	-1.8
Angina (self-reported)	0.3	0.5	1.4	-0.4	-0.8	-0.4	-0.0	-0.3	-0.6	-0.0	-1.2	-1.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.3	0.3	1.1	-0.3	0.5	-0.5	-0.3	0.5	0.6	1.1	-0.5	-0.4
Supplements: Vitamin C	0.3	0.3	0.8	-0.1	-0.4	0.0	-0.8	-0.4	-0.7	-0.9	-0.3	-0.5
Whole body fat-free mass	0.3	1.7	9.2	3.0	-0.9	0.8	0.5	-0.0	0.8	1.7	-0.5	0.7
Ever had stillbirth, spontaneous miscarriage or termination	0.3	0.3	1.2	1.1	-0.2	0.2	0.0	0.7	-0.2	0.8	0.5	-0.1
Commuting to job workplace: Walk	0.3	0.3	1.3	1.2	0.4	0.1	-0.7	0.2	-0.8	-0.3	-0.2	0.5
Whole body water mass	0.3	1.7	9.3	3.1	-0.9	0.7	0.5	-0.1	0.8	1.7	-0.5	0.8
Eye problems/disorders: Glaucoma	0.3	0.3	1.7	0.3	0.5	-0.0	0.1	0.8	0.3	1.3	0.1	-0.2
Pain type(s) experienced in last month: Hip pain	0.3	0.4	2.2	0.0	0.1	0.4	1.5	-0.1	0.2	-0.3	0.7	0.7
Average weekly beer plus cider intake	0.3	0.4	1.6	-1.3	-0.4	0.0	-0.2	0.3	-0.1	0.1	0.3	-1.3
Ever had prostate specific antigen (PSA) test	0.3	0.3	1.1	0.6	0.6	0.0	0.6	0.4	0.5	1.1	-0.1	-0.3
Fractured/broken bones in last 5 years	0.3	0.4	1.1	-1.0	0.8	0.2	0.2	1.0	0.8	-0.2	-0.0	-0.7
Basal cell carcinoma (self-reported)	0.3	0.4	1.2	-0.0	-0.5	-1.1	-0.6	-0.6	-0.5	0.2	-0.9	0.4
Alcohol drinker status: Previous	0.3	0.3	1.0	0.9	-0.3	0.1	-0.3	-0.7	-0.4	-0.5	0.1	1.0
Schizophrenia (2018)	0.2	0.5	2.2	-0.8	-0.5	-0.2	-0.1	0.8	0.3	0.4	-0.7	-1.5
LDL Cholesterol	0.2	0.2	0.8	0.4	-0.2	-0.0	-0.9	-0.6	-0.7	-0.4	-0.2	-0.3
Systolic blood pressure, automated reading	0.2	0.7	1.6	0.7	-0.6	-1.3	0.5	-1.0	0.4	0.7	-0.7	1.1
Angina	0.2	0.3	1.0	-0.4	-0.7	-0.2	0.2	-0.1	-0.4	0.1	-1.0	-1.0
Leg fat-free mass (left)	0.2	1.3	7.1	2.7	-1.1	0.8	0.3	-0.4	0.2	0.9	-0.7	0.9
Medication: Atenolol	0.2	0.3	0.7	-0.4	-0.6	-0.7	-0.1	-0.5	-0.8	-0.5	-0.7	-0.2
Leg predicted mass (left)	0.2	1.2	6.4	2.5	-1.2	0.7	0.2	-0.4	0.1	0.8	-0.8	0.8
Hearing difficulty/problems with background noise	0.2	0.4	1.1	0.2	-1.0	-0.6	-0.7	-0.6	-0.3	0.1	-1.0	0.0
Allergy	0.2	0.5	2.3	1.5	0.3	1.3	0.4	-0.0	-0.4	0.3	0.5	-0.0
Medication: Ramipril	0.2	0.3	1.0	0.1	-0.4	-0.5	1.0	-1.0	0.3	-0.1	-0.4	-0.1
Father’s age at death	0.2	0.2	0.5	-0.7	0.1	-0.0	0.6	0.6	0.3	0.1	-0.3	-0.6
Qualifications: A levels/AS levels or equivalent	0.2	0.3	1.0	-0.9	1.0	0.1	0.3	0.4	0.8	0.3	0.4	-0.3
Birth weight of first child	0.2	0.4	1.4	0.7	-0.9	-0.5	-0.3	-0.5	-0.6	-0.1	-1.2	0.0
Loud music exposure frequency	0.2	0.3	1.0	1.0	-0.1	0.5	0.7	-0.1	-0.4	0.4	-0.0	0.5
Overall health rating	0.2	0.5	0.9	1.0	-0.6	0.2	-0.6	-0.1	-0.9	-0.6	-0.7	0.8
Family relationship satisfaction	0.2	0.3	1.3	0.4	-0.5	-0.6	0.0	-1.2	-0.2	-0.7	0.3	0.2
Leg fat-free mass (right)	0.2	0.9	4.8	2.2	-1.2	0.3	-0.1	-0.5	0.0	0.8	-0.9	0.8
Loneliness, isolation	0.2	0.3	1.7	-0.0	-0.0	0.1	-0.5	0.5	0.2	-0.4	0.3	1.3
Friendships satisfaction	0.2	0.3	0.7	0.7	-0.5	0.2	0.5	-0.8	-0.5	-0.6	-0.0	0.1
Leg predicted mass (right)	0.2	1.0	5.1	2.2	-1.1	0.3	0.0	-0.4	0.1	0.9	-0.8	0.9
Commuting to job workplace: Public transport	0.2	0.3	1.1	0.1	-0.1	-0.6	-1.1	-0.3	-0.7	0.0	-0.3	0.5
Risk taking	0.2	0.4	1.4	-0.9	-0.3	0.3	0.7	0.1	1.2	-0.5	0.2	0.4
Supplements: Calcium	0.2	0.3	1.1	-0.4	-0.1	0.0	-1.1	-0.2	-0.2	-0.3	-0.2	-1.0
Heart disease (siblings)	0.2	0.2	0.7	0.3	-0.4	-0.5	-0.4	-0.1	-0.6	0.4	-0.6	0.9
Tanning	0.1	0.9	2.5	-1.6	-0.2	-0.9	-1.1	0.1	0.1	-0.1	-1.1	-1.5
Bilateral oophorectomy (both ovaries removed)	0.1	0.2	0.4	-0.1	-0.2	0.2	0.7	-0.5	-0.1	-0.6	-0.1	0.5
Tinnitus: Yes, but not now, but have in the past	0.1	0.1	0.7	0.1	-0.3	-0.2	0.0	0.1	-0.4	0.1	-0.8	-0.3
Sitting height	0.1	0.8	4.3	0.3	-0.3	-0.4	-0.6	0.4	0.7	1.1	-0.5	-2.1
Alcohol usually taken with meals	0.1	0.1	0.6	0.8	0.3	0.5	0.1	0.3	0.4	-0.0	0.3	-0.1
Qualifications: None of the above	0.1	0.3	0.8	-0.2	0.5	0.9	0.2	0.9	0.4	-0.4	0.4	-0.3
Happiness	0.1	0.2	0.7	0.2	0.4	0.0	0.1	-0.1	-0.1	0.0	0.8	0.7
Qualifications: O levels/GCSEs or equivalent	0.1	0.2	0.6	-0.7	0.1	-0.5	0.1	-0.4	-0.2	-0.8	0.1	0.0
Glaucoma (self-reported)	0.1	0.1	0.7	0.3	-0.1	-0.5	-0.3	0.1	-0.1	0.8	-0.1	0.2
Gout (self-reported)	0.1	0.1	0.4	-0.0	-0.5	-0.2	-0.1	-0.0	0.6	0.2	-0.3	0.1
Hypothyroidism/myxoedema (self-reported)	0.1	0.2	1.4	-0.4	-0.3	-0.1	-0.2	-0.2	-0.3	-1.2	0.1	0.4
Number of children fathered	0.1	0.1	0.3	0.5	-0.2	0.1	-0.4	0.0	-0.3	-0.3	-0.1	0.4
Reason for reducing amount of alcohol drunk: Health precaution	0.1	0.1	0.8	0.2	-0.3	-0.2	0.9	0.0	0.4	-0.0	-0.4	-0.2
Migraine (self-reported)	0.1	0.1	0.2	-0.1	-0.3	0.5	-0.1	-0.4	-0.4	-0.3	0.1	-0.4
Medication: Allopurinol	0.1	0.1	0.6	-0.0	-0.7	-0.1	0.1	-0.3	-0.1	-0.5	-0.4	0.3
Heart disease (mother)	0.1	0.1	0.4	0.1	-0.6	-0.2	-0.3	-0.5	-0.3	-0.4	-0.2	-0.3
Chest pain or discomfort	0.1	0.1	0.6	0.2	-0.3	0.3	-0.1	0.2	-0.3	-0.6	-0.7	0.3
Leg pain on walking	0.1	0.1	0.3	-0.0	0.2	-0.3	-0.1	0.6	-0.0	0.3	-0.1	0.4
Knee pain experienced in last month	0.1	0.1	0.4	-0.6	0.0	-0.4	-0.0	-0.1	0.2	-0.4	0.2	0.3
Handedness (chirality/laterality): Left-handed	0.1	0.2	0.4	-0.5	0.5	0.2	0.6	0.3	0.5	-0.4	-0.2	-0.1
Mother’s age at death	0.1	0.2	0.5	-0.7	0.2	-0.5	-0.3	0.4	0.0	-0.4	-0.2	-0.7
Number of operations (self-reported)	0.1	0.1	0.6	0.3	0.1	0.1	0.8	-0.1	-0.1	-0.0	-0.3	0.1
Commuting to job workplace: Cycle	0.1	0.1	0.3	-0.2	0.3	-0.6	-0.4	0.1	0.2	0.6	0.2	-0.5

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