TWAS hub - PELI3

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	YFS	Blood	0.0107	0.0053	0.0021	0.014	0.006	0.007	0.005	0.009	1.6e-05	0.0046	0.0016	0.0062	0.00054
2	TCGA	Thyroid Carcinoma	0.0370	0.0290	0.0029	0.035	0.020	0.028	NA	0.027	2.1e-04	0.0046	0.0009	NA	0.00110

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Supplements: Fish oil (including cod liver oil)	14.3	18.7	21.6	-4.7	-4.0
Supplements: Calcium	10.8	11.9	13.9	-3.7	-3.1
Overall health rating	9.1	19.6	20.8	4.6	4.3
Mineral and other dietary supplements	9.1	12.2	13.8	3.7	3.3
Commuting to job workplace: Cycle	8.6	10.4	10.6	-3.2	-3.2
Peak expiratory flow (PEF)	7.7	17.8	19.2	-4.1	-4.4
Forced expiratory volume in 1-second (FEV1)	7.5	25.4	27.2	-4.9	-5.2
Forced vital capacity (FVC)	7.3	28.1	32.3	-4.9	-5.7
Health satisfaction	7.3	9.5	10.4	2.9	3.2
Seen doctor (GP) for nerves, anxiety, tension or depression	7.1	10.9	11.4	3.2	3.4
Supplements: Glucosamine	6.9	9.0	10.5	-3.2	-2.8
Number of self-reported non-cancer illnesses	6.9	12.0	13.5	3.2	3.7
Cholesterol lowering medication	6.9	10.2	10.6	3.1	3.2
Forced vital capacity (FVC), Best measure	6.8	24.7	29.2	-4.5	-5.4
Asthma	6.7	13.3	14.0	3.7	3.5
LDL Cholesterol	6.6	10.5	13.7	3.7	2.7
Respiratory disease	6.5	14.5	14.6	3.8	3.8
Forced expiratory volume in 1-second (FEV1), Best measure	6.5	20.6	22.5	-4.3	-4.7
Average weekly red wine intake	6.4	9.5	9.5	-3.1	-3.1
Asthma (self-reported)	6.4	12.8	13.3	3.6	3.5
Breast Cancer	5.9	14.2	18.7	-4.3	-3.1
Lung FVC	5.9	30.2	31.6	-5.4	-5.6
Medication: Co-codamol	5.8	6.7	7.7	2.4	2.8
Long-standing illness, disability or infirmity	5.5	8.4	9.5	2.7	3.1
Medication: Seretide 50 evohaler	5.4	6.2	7.3	2.7	2.3
Hand grip strength (left)	5.3	14.0	15.5	-3.9	-3.5
Frequency of tiredness / lethargy in last 2 weeks	5.1	8.2	9.9	3.1	2.6
Bipolar Disorder (2018)	5.0	7.9	8.0	2.8	2.8
Primary Biliary Cirrhosis	4.7	6.7	6.9	2.6	2.6
Taking other prescription medications	4.7	7.3	7.6	2.8	2.6
Qualifications: nursing, teaching	4.6	7.1	10.2	-2.0	-3.2
Heart attack/myocardial infarction (self-reported)	4.5	5.8	7.7	-2.0	-2.8
Arm fat percentage (right)	4.3	16.8	17.4	4.2	4.0
Qualifications: NVQ or HND or HNC or equivalent	4.3	5.2	5.4	2.3	2.2
Heart attack	4.1	5.3	7.1	-1.9	-2.7
Bipolar Disorder or Schizophrenia	4.0	9.8	11.3	2.9	3.4
Arm fat percentage (left)	3.9	15.4	15.9	4.0	3.9
Number of incorrect matches in round	3.8	6.2	7.8	-2.8	-2.2
Number of treatments/medications taken	3.7	6.7	7.0	2.5	2.6
Number of operations (self-reported)	3.7	5.5	5.5	2.3	2.3
Allergy	3.6	8.3	8.7	-3.0	-2.8
Suffer from ‘nerves’	3.6	5.7	6.1	-2.5	-2.3
Qualifications: A levels/AS levels or equivalent	3.5	7.7	8.5	-2.6	-2.9
Diabetes diagnosed by doctor	3.5	5.7	6.0	2.5	2.3
Heart disease (siblings)	3.5	4.4	4.4	2.1	2.1
Vitamin and mineral supplements	3.4	4.7	4.7	2.2	2.1
Medication: Simvastatin	3.4	5.0	5.0	2.2	2.2
Birth weight of first child	3.3	6.0	7.1	-2.2	-2.7
Shortness of breath walking on level ground	3.2	3.8	4.2	2.1	1.8
Alcohol usually taken with meals	3.1	5.0	5.3	-2.2	-2.3
Diabetes (self-reported)	2.9	4.4	4.8	2.2	2.0
Fed-up feelings	2.8	5.1	5.3	2.3	2.2
Body mass index (BMI)	2.8	11.8	11.9	3.4	3.5
Noisy workplace	2.8	3.5	4.5	2.1	1.5
Pulse wave peak to peak time	2.8	3.3	5.1	-2.2	-1.2
High cholesterol (Self-reported)	2.8	4.9	6.7	1.8	2.6
Birth weight	2.7	5.9	6.3	2.5	2.4
Ever taken oral contraceptive pill	2.7	3.0	4.5	-2.1	-1.2
Diverticular disease/diverticulitis (self-reported)	2.6	3.1	3.2	-1.7	-1.8
Lung cancer (father)	2.6	3.1	3.3	1.8	1.7
Blood Red Count	2.5	24.1	24.3	4.9	4.9
Arm fat mass (right)	2.5	10.3	11.4	3.4	3.0
Blood clot in the leg (DVT)	2.5	3.2	4.2	2.0	1.5
Bilateral oophorectomy (both ovaries removed)	2.4	2.8	3.4	1.8	1.5
Tinnitus: Yes, but not now, but have in the past	2.4	2.6	2.6	1.6	1.6
Medication: Ibuprofen (e.g. Nurofen)	2.4	3.0	3.6	-1.9	-1.5
Worry too long after embarrassment	2.4	4.1	5.5	2.4	1.6
Qualifications: College or University degree	2.4	7.5	9.4	-2.4	-3.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	2.4	2.9	3.9	-2.0	-1.4
Medication: Lisinopril	2.4	3.2	5.4	-2.3	-1.0
Schizophrenia (2014)	2.3	5.0	8.0	1.4	2.8
Ulcerative Colitis	2.3	3.3	3.4	1.8	1.9
Illnesses of siblings	2.3	3.2	3.5	-1.9	-1.7
Wheeze or whistling in the chest in last year	2.3	4.1	4.9	2.2	1.8
Forced expiratory volume in 1-second (FEV1), predicted percentage	2.3	4.9	5.6	-2.1	-2.4
Other serious medical condition/disability diagnosed by doctor	2.2	2.8	3.5	1.4	1.9
Current tobacco smoking	2.2	3.7	4.3	1.7	2.1
Depression (self-reported)	2.2	2.6	4.6	0.8	2.2
Arm fat mass (left)	2.2	8.8	9.9	3.1	2.8
Deep venous thrombosis (DVT) (self-reported)	2.2	2.9	3.8	2.0	1.4
Intelligence (Savage-Jansen 2018)	2.1	6.4	7.4	-2.3	-2.7
Alzheimer’s Disease (in mother)	2.1	2.4	2.8	-1.7	-1.4
Lupus	2.1	3.2	3.3	-1.8	-1.8
Height	2.1	40.3	48.9	-5.6	-7.0
Serious illness, injury or assault to yourself	2.1	2.5	4.2	0.9	2.0
Multivitamins +/- minerals	2.1	2.7	3.0	-1.6	-1.7
High blood pressure (mother)	2.1	3.0	3.0	-1.7	-1.7
Hayfever/allergic rhinitis (self-reported)	2.1	2.8	3.7	1.9	1.4
Leg fat percentage (right)	2.1	7.6	9.2	2.4	3.0
Comparative height size at age 10	2.1	11.5	12.7	-3.2	-3.6
Medication for cholesterol	2.1	3.2	3.7	-1.6	-1.9
Pulse wave Arterial Stiffness index	2.0	2.3	3.9	2.0	0.9
Reason for reducing amount of alcohol drunk: Health precaution	2.0	2.3	3.5	-1.9	-1.1
Migraine (self-reported)	2.0	2.5	2.6	1.6	1.6
Pulse rate, automated reading	2.0	6.5	6.7	2.6	2.5
Hearing aid user	2.0	2.3	3.9	0.9	2.0
Medication: Atenolol	1.9	2.3	2.4	-1.6	-1.5
Body fat percentage	1.9	7.3	7.7	2.6	2.8
Alcohol intake frequency.	1.9	4.4	6.5	2.5	1.5
Average weekly beer plus cider intake	1.9	2.7	4.2	1.1	2.1
Schizophrenia (2018)	1.8	3.7	5.3	1.4	2.3
BMI	1.8	10.3	11.8	3.0	3.4
Hand grip strength (right)	1.8	4.9	5.1	-2.3	-2.2
Medication: Bendroflumethiazide	1.8	2.7	3.1	1.8	1.5
Impedance of leg (left)	1.7	8.3	10.6	-3.3	-2.5
Nervous feelings	1.7	3.2	3.8	-1.6	-1.9
Financial difficulties in last 2 years	1.7	2.3	3.3	1.1	1.8
Standing height	1.7	17.1	22.8	-3.4	-4.8
Leg fat percentage (left)	1.7	6.3	7.7	2.2	2.8
Relative age of first facial hair	1.6	3.2	5.1	2.3	1.2
Falls in the last year	1.6	2.2	3.7	1.9	0.8
Exposure to tobacco smoke at home	1.6	1.8	2.5	1.0	1.6
Tense / ‘highly strung’	1.6	2.6	4.1	-2.0	-1.1
Ever had stillbirth, spontaneous miscarriage or termination	1.6	1.7	1.9	1.4	1.2
Osteoporosis (self-reported)	1.6	1.9	2.1	1.4	1.3
Prostate Cancer	1.5	2.1	3.7	-1.9	-0.7
Pain all over the body in last month	1.5	1.6	2.0	1.4	1.1
Fluid intelligence score	1.5	3.0	4.7	-1.2	-2.2
Medication: Blood pressure	1.5	2.8	2.8	1.6	1.7
Impedance of leg (right)	1.4	6.7	8.8	-3.0	-2.2
Qualifications: None of the above	1.4	2.9	3.8	1.4	1.9
Pulse rate	1.4	2.3	2.7	1.6	1.4
Medication: Amlodipine	1.4	2.0	2.4	-1.3	-1.5
Medication: Allopurinol	1.4	1.8	2.5	-1.6	-1.1
Mood swings	1.4	2.6	2.7	1.7	1.6
Smoking status: Current	1.4	2.3	2.6	1.4	1.6
Myopia	1.4	2.1	2.2	-1.4	-1.5
Ulcerative Colitis (UC)	1.3	2.5	3.2	1.3	1.8
Type 2 Diabetes (T2D) (2018)	1.3	2.4	2.6	1.6	1.5
Ever had hysterectomy (womb removed)	1.3	1.5	1.6	1.3	1.2
Mean time to correctly identify matches	1.3	2.4	3.5	1.9	1.1
Leg fat mass (right)	1.3	5.0	5.6	2.1	2.4
Chest pain or discomfort	1.3	1.8	2.7	1.6	1.0
Wears glasses or contact lenses	1.3	1.5	1.8	1.3	1.1
Triglycerides	1.2	2.0	2.3	1.3	1.5
Pack years adult smoking proportion	1.2	1.9	2.4	1.2	1.6
Number of full brothers	1.2	1.6	2.6	-1.6	-0.8
Age at first live birth	1.2	2.0	2.2	-1.4	-1.5
Angina (self-reported)	1.2	1.6	1.6	-1.2	-1.2
Number of full sisters	1.2	1.5	2.7	0.5	1.6
Financial situation satisfaction	1.2	1.5	2.0	1.0	1.4
Unable to work because of sickness or disability	1.2	1.5	2.2	1.5	0.9
Basal cell carcinoma (self-reported)	1.2	1.4	1.7	1.3	1.0
Leg fat mass (left)	1.2	4.5	5.0	2.0	2.2
Age when periods started (menarche)	1.1	2.7	2.7	1.6	1.6
Waist circumference	1.1	4.2	4.2	2.1	2.0
Pack years of smoking	1.1	1.6	2.2	1.0	1.5
Ever used hormone-replacement therapy (HRT)	1.0	1.2	1.6	0.9	1.3
Trunk fat percentage	1.0	4.2	4.3	2.1	2.0
Medication: Blood pressure	1.0	1.8	1.8	-1.3	-1.4
Medication: Ibuprofen	1.0	1.2	1.3	-1.1	-1.1
Whole body fat mass	1.0	4.4	4.5	2.1	2.0
Mouth/teeth dental problems: Mouth ulcers	1.0	1.6	2.7	-1.6	-0.8
Average weekly champagne plus white wine intake	1.0	1.3	1.5	-1.1	-1.2
Worry (Nagel 2018)	0.9	1.9	2.4	-1.6	-1.2
Cardiovascular Disease	0.9	2.8	4.1	1.3	2.0
Angina	0.9	1.2	1.2	-1.1	-1.1
Hearing difficulty/problems with background noise	0.9	1.4	2.6	0.4	1.6
Medication: Ventolin 100micrograms inhaler	0.9	1.2	1.7	0.9	1.3
Medication: Omeprazole	0.9	1.1	1.7	0.7	1.3
Leg pain on walking	0.9	1.1	2.0	1.4	0.4
Supplements: Vitamin C	0.9	1.1	1.2	-1.1	-1.0
Tinnitus: Yes, now most or all of the time	0.9	1.0	1.1	1.0	1.0
Alcohol drinker status: Never	0.9	1.1	2.0	1.4	0.5
Verbal and Numeric Reasoning (VNR)	0.8	2.0	3.0	-1.0	-1.7
Average weekly spirits intake	0.8	1.0	1.6	-1.3	-0.6
Hearing difficulty/problems: Yes	0.8	1.2	1.9	0.8	1.4
Headache pain in last month	0.8	1.4	1.6	1.3	1.0
Neck or shoulder pain in last month	0.8	1.2	2.4	-1.5	-0.1
Family relationship satisfaction	0.8	0.9	1.2	0.8	1.1
Guilty feelings	0.8	1.2	1.2	-1.1	-1.1
Illnesses of father: High blood pressure	0.8	1.0	1.3	-0.8	-1.1
Reaction Time	0.7	1.3	2.5	1.6	0.5
HbA1C	0.7	0.7	0.8	-0.8	-0.9
Type 2 Diabetes (T2D) (2012)	0.7	0.8	1.1	0.6	1.1
Trunk fat mass	0.7	2.9	3.2	1.8	1.6
Happiness	0.7	0.9	1.4	1.2	0.6
Age at last live birth	0.7	1.0	1.1	-1.0	-1.1
Illness, injury, bereavement, stress in last 2 years	0.7	0.8	1.0	-0.8	-1.0
Handedness (chirality/laterality): Left-handed	0.7	0.9	1.5	-1.2	-0.5
Pain experienced in last month	0.7	1.2	1.6	-0.9	-1.3
Depressed Affect (Nagel 2018)	0.6	1.2	1.6	1.2	0.9
Ovarian Cancer	0.6	0.8	1.0	0.8	1.0
Chronotype (morning person)	0.6	1.4	1.6	-1.2	-1.1
Eye problems/disorders: Diabetes related eye disease	0.6	0.7	1.1	-1.0	-0.5
Hayfever, allergic rhinitis or eczema	0.6	1.4	1.5	1.2	1.1
Sitting height	0.6	4.2	6.1	-1.5	-2.5
Medication: Ramipril	0.6	0.8	1.3	1.1	0.5
Seen a psychiatrist for nerves, anxiety, tension or depression	0.6	0.8	1.0	0.8	1.0
Commuting to job workplace: Car/motor vehicle	0.6	0.7	1.3	-0.4	-1.1
Ever had bowel cancer screening	0.6	0.7	0.9	0.8	1.0
Impedance of whole body	0.6	3.1	3.4	-1.9	-1.7
Depression (Nagel 2018)	0.5	0.8	0.9	-0.9	-0.9
Coronary Artery Disease (CAD)	0.5	0.6	0.7	-0.9	-0.6
Heel T-Score	0.5	4.1	6.0	-2.4	-1.5
Hypothyroidism (self reported)	0.5	1.2	1.3	1.0	1.2
Hair Pigment	0.5	15.7	20.9	-4.6	-3.2
Heel bone mineral density (BMD) T-score, automated (right)	0.5	1.2	1.2	-1.1	-1.1
Weight	0.5	2.3	3.2	1.8	1.1
Ever smoked	0.5	0.9	1.8	-1.4	-0.2
Risk taking	0.5	0.7	1.0	-1.0	-0.6
Age started oral contraceptive pill	0.5	0.6	0.8	0.9	0.7
Ever depressed for a whole week	0.5	0.6	1.0	0.5	1.0
Crohns Disease (2017)	0.4	0.9	1.3	-1.2	-0.7
Body Mass Index (BMI) (2010)	0.4	0.5	1.0	1.0	0.1
Crohns Disease (2012)	0.4	0.7	0.9	-0.6	-0.9
Medication: Metformin	0.4	0.5	0.6	0.7	0.8
Townsend deprivation index at recruitment	0.4	0.6	0.6	0.7	0.8
Maternal smoking around birth	0.4	0.6	0.7	0.8	0.8
Ever unenthusiastic/disinterested for a whole week	0.4	0.5	0.9	0.2	0.9
Number of live births	0.4	0.6	1.0	0.5	1.0
Length of working week for main job	0.4	0.5	0.5	0.7	0.6
Loud music exposure frequency	0.4	0.4	0.8	0.2	0.9
Mouth/teeth dental problems: Loose teeth	0.4	0.5	0.7	-0.6	-0.8
Knee pain experienced in last month	0.4	0.6	0.7	0.9	0.7
Ever had prostate specific antigen (PSA) test	0.4	0.5	0.8	0.9	0.4
Medication: Omeprazole (e.g. Zanprol)	0.4	0.5	1.0	0.4	1.0
Alcohol drinker status: Previous	0.4	0.5	0.6	-0.7	-0.8
Mean Putamen Volume	0.3	0.3	0.3	-0.6	-0.5
Fasting Glucose	0.3	0.4	0.7	-0.1	-0.9
HDL Cholesterol	0.3	0.5	0.7	-0.8	-0.6
Neuroticism (2016)	0.3	0.5	0.9	-0.2	-0.9
Blood Eosinophil Count	0.3	2.7	5.3	-2.3	-0.2
Blood White Count	0.3	2.2	3.1	-1.8	-1.1
Waist Hip Ratio (WHR)	0.3	1.3	1.6	1.0	1.3
Neuroticism	0.3	0.6	0.9	1.0	0.6
Frequency of unenthusiasm / disinterest in last 2 weeks	0.3	0.4	0.7	0.4	0.8
Qualifications: CSEs or equivalent	0.3	0.3	0.7	-0.0	-0.8
Chronic bronchitis/emphysema (father)	0.3	0.4	0.4	0.6	-0.6
Past tobacco smoking	0.3	0.6	1.2	1.1	-0.0
Hair/balding pattern: Pattern 2	0.3	0.4	0.8	0.9	0.3
Father’s age at death	0.3	0.4	0.6	-0.4	-0.8
Qualifications: O levels/GCSEs or equivalent	0.3	0.5	0.8	-0.5	-0.9
Hypothyroidism/myxoedema (self-reported)	0.3	0.6	0.6	0.8	0.7
Illnesses of siblings: Diabetes	0.3	0.4	0.6	0.4	0.8
Back pain experienced in last month	0.3	0.5	0.7	0.4	0.9
Breast cancer (self-reported)	0.3	0.3	0.5	0.5	0.7
Commuting to job workplace: Public transport	0.3	0.3	0.6	-0.8	-0.2
Alzheimer’s Disease (including proxy)	0.2	0.3	0.4	-0.6	-0.5
Age at First Birth	0.2	0.2	0.3	0.6	0.3
Rheumatoid Arthritis	0.2	0.3	0.5	-0.7	-0.2
Blood Platelet Count	0.2	2.7	3.0	-1.7	-1.6
Systolic Blood Pressure	0.2	0.9	1.8	1.4	0.3
Smoking Status	0.2	0.4	0.8	-0.1	0.9
Tanning	0.2	3.0	4.1	2.0	1.4
Systolic blood pressure, automated reading	0.2	0.6	1.0	1.0	0.3
Diabetes (father)	0.2	0.2	0.5	-0.1	-0.7
Diabetes (mother)	0.2	0.3	0.5	-0.2	-0.7
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.5	0.7	-0.8	-0.6
High blood pressure	0.2	0.6	1.0	0.5	1.0
Leg predicted mass (left)	0.2	0.8	1.6	1.3	0.1
Impedance of arm (right)	0.2	0.8	1.3	-0.6	-1.1
Time employed in main current job	0.2	0.3	0.3	-0.5	-0.5
Worrier / anxious feelings	0.2	0.4	0.7	-0.9	-0.0
Hair/balding pattern: Pattern 3	0.2	0.2	0.3	-0.6	0.4
Impedance of arm (left)	0.2	1.1	1.5	-0.8	-1.2
Breastfed as a baby	0.2	0.3	0.4	-0.5	-0.6
Gout (self-reported)	0.2	0.3	0.6	-0.7	-0.2
High blood pressure (siblings)	0.2	0.3	0.4	0.6	0.6
Number of children fathered	0.2	0.2	0.5	-0.7	0.0
Emphysema/chronic bronchitis	0.2	0.2	0.5	-0.1	0.7
Had major operations	0.2	0.3	0.5	-0.7	-0.3
Hypertension (Self-reported)	0.2	0.7	1.0	0.6	1.0
Medication: Gliclazide	0.2	0.2	0.4	0.7	0.2
Neuroticism (Nagel 2018)	0.1	0.2	0.3	0.6	0.3
Schizophrenia vs Biploar Disorder	0.1	0.1	0.1	-0.3	-0.4
Alzheimer’s Disease (in father)	0.1	0.1	0.1	0.2	0.4
Irritable Bowel Disease (IBD)	0.1	0.3	0.6	0.3	0.8
Major Depression (MDD)	0.1	0.2	0.2	-0.3	0.5
Bipolar Disorder (2011)	0.1	0.1	0.2	0.1	0.4
Allergy or Eczema	0.1	0.3	0.4	0.6	0.4
Frequency of depressed mood in last 2 weeks	0.1	0.1	0.1	0.2	0.4
Medication for hormone replacement therapy	0.1	0.1	0.1	-0.3	-0.2
Leg fat-free mass (left)	0.1	0.8	1.6	1.3	0.1
Average weekly fortified wine intake	0.1	0.2	0.3	-0.5	-0.2
Relative age voice broke	0.1	0.2	0.4	0.7	0.0
Medication: Levothyroxine sodium	0.1	0.2	0.3	0.6	0.2
Frequency of tenseness / restlessness in last 2 weeks	0.1	0.2	0.3	-0.0	0.6
Trunk fat-free mass	0.1	0.8	1.6	-0.2	-1.3
Alcohol intake versus 10 years previously	0.1	0.2	0.3	0.5	0.4
Serious illness, injury or assault of a close relative in last 2 years	0.1	0.1	0.1	-0.4	-0.3
Mouth/teeth dental problems: Dentures	0.1	0.2	0.4	0.6	-0.2
Medication: Lansoprazole	0.1	0.1	0.2	0.5	0.3
Prospective memory result	0.1	0.1	0.2	-0.0	-0.5
Illnesses of mother	0.1	0.1	0.2	0.4	0.1
Trunk predicted mass	0.1	0.8	1.6	-0.2	-1.3
Pulse wave reflection index	0.1	0.1	0.2	0.5	-0.2
Ever highly irritable/argumentative for 2 days	0.1	0.1	0.1	0.3	0.3
Medication: Paracetamol	0.1	0.1	0.3	-0.2	-0.5
Medication for cholesterol, blood pressure or diabetes	0.1	0.1	0.1	0.3	0.3
Glaucoma (self-reported)	0.1	0.1	0.2	0.5	-0.2
Exposure to tobacco smoke outside home	0.1	0.2	0.2	-0.5	0.3
Comparative body size at age 10	0.1	0.2	0.5	-0.1	0.7
Heart disease (mother)	0.1	0.1	0.2	-0.5	-0.2
Arm predicted mass (right)	0.1	0.4	0.8	-0.1	-0.9
Medication: Aspirin	0.1	0.1	0.2	-0.1	-0.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.1	0.1	0.1	-0.3	-0.3
Smoking status: Previous	0.1	0.2	0.3	-0.6	0.3
Forced expiratory volume in 1-second (FEV1), predicted	0.1	0.3	0.5	0.3	-0.7
Whole body fat-free mass	0.1	0.5	1.0	0.2	-1.0
Leg fat-free mass (right)	0.1	0.5	1.0	1.0	-0.3
Loneliness, isolation	0.1	0.1	0.1	0.4	0.4
Friendships satisfaction	0.1	0.1	0.1	-0.4	-0.3
Medication: Aspirin	0.1	0.1	0.2	-0.2	-0.5
Illnesses of father: None of the above (group 1)	0.1	0.1	0.2	0.2	0.5
Whole body water mass	0.1	0.5	0.8	0.3	-0.9
Leg predicted mass (right)	0.1	0.6	1.0	1.0	-0.3
Pain type(s) experienced in last month: Hip pain	0.1	0.1	0.2	-0.5	-0.1
Basal metabolic rate	0.1	0.3	0.4	0.6	-0.5
Arm fat-free mass (left)	0.1	0.3	0.6	0.2	-0.8
Irritability	0.1	0.2	0.3	-0.6	-0.2
Diastolic blood pressure, automated reading	0.1	0.2	0.3	0.5	0.3
Vascular/heart problems diagnosed by doctor	0.1	0.4	0.6	-0.5	-0.8
Lung FEV1/FVC ratio	0.0	0.1	0.2	0.1	0.5
Sensitivity / hurt feelings	0.0	0.0	0.0	-0.2	-0.2
Supplements: Zinc	0.0	0.0	0.0	-0.1	-0.0
Severe depression (siblings)	0.0	0.0	0.0	-0.1	-0.2
Stomach or abdominal pain in last month	0.0	0.0	0.1	0.3	0.0
Had menopause	0.0	0.0	0.0	-0.0	0.0
Had other major operations	0.0	0.0	0.1	0.3	-0.0
Mouth/teeth dental problems	0.0	0.1	0.1	0.2	0.3
Neuroticism score	0.0	0.0	0.0	0.0	-0.1
Hip circumference	0.0	0.1	0.2	0.4	-0.1
Medication: Cholesterol lowering	0.0	0.0	0.0	0.0	-0.0
Hair/balding pattern: Pattern 4	0.0	0.1	0.2	-0.5	-0.1
Mouth/teeth dental problems: Bleeding gums	0.0	0.0	0.1	-0.0	0.2
Chronic bronchitis/emphysema (mother)	0.0	0.0	0.0	-0.1	-0.0
Arm fat-free mass (right)	0.0	0.2	0.5	0.1	-0.7
Eye problems/disorders: None of the above	0.0	0.0	0.0	-0.0	-0.2
Medication for pain relief, constipation, heartburn	0.0	0.0	0.1	-0.3	0.0
Illnesses of father: Heart disease	0.0	0.0	0.0	-0.1	0.1
Commuting to job workplace: Walk	0.0	0.0	0.0	-0.1	0.2
Eye problems/disorders: Cataract	0.0	0.0	0.1	0.0	0.3
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.0	0.0	0.0	0.1	0.0
Osteoarthritis (self-reported)	0.0	0.1	0.1	0.1	0.3
Miserableness	0.0	0.0	0.0	-0.0	-0.1
Mother’s age at death	0.0	0.0	0.1	0.2	0.1
Eye problems/disorders: Glaucoma	0.0	0.0	0.1	0.3	-0.0
Medication: Paracetamol	0.0	0.1	0.1	0.4	0.1
Medication: Atorvastatin	0.0	0.0	0.1	0.2	0.1
Fractured/broken bones in last 5 years	0.0	0.1	0.1	-0.1	-0.3
Arm predicted mass (left)	0.0	0.2	0.2	0.4	-0.5

Hub : Genes

PELI3

Models

Trait associations