TWAS hub - PGA3

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	TCGA	Breast Invasive Carcinoma	0.1155	0.0433	2.7e-11	0.068	0.056	0.067	NA	0.069	8.4e-14	1.1e-11	1.1e-13	NA	6.5e-14
2	TCGA	Esophageal Carcinoma	0.0790	0.0450	1.4e-03	0.061	0.071	0.065	NA	0.055	5.4e-03	2.8e-03	4.2e-03	NA	7.8e-03
3	TCGA	Head and Neck Squamous Cell Carcinoma	0.2066	0.0727	3.9e-12	0.132	0.108	0.128	NA	0.127	1.5e-14	3.6e-12	3.1e-14	NA	4.5e-14
4	TCGA	Kidney Renal Papillary Cell Carcinoma	0.2540	0.1410	2.7e-04	0.087	0.040	0.086	NA	0.087	1.2e-05	2.4e-03	1.2e-05	NA	1.1e-05
5	TCGA	Brain Lower Grade Glioma	0.0319	0.0253	4.2e-03	0.036	0.024	0.030	NA	0.032	4.8e-05	8.5e-04	2.0e-04	NA	1.3e-04
6	TCGA	Lung Squamous Cell Carcinoma	0.0907	0.0416	1.6e-05	0.053	0.023	0.029	NA	0.038	1.2e-06	1.1e-03	2.9e-04	NA	3.7e-05
7	TCGA	Ovarian Serous Cystadenocarcinoma	0.0790	0.0530	5.4e-03	0.063	0.023	0.053	NA	0.054	4.8e-05	1.1e-02	1.7e-04	NA	1.4e-04
8	TCGA	Prostate Adenocarcinoma	0.0922	0.0502	2.4e-03	0.027	0.027	0.025	NA	0.020	7.2e-04	7.0e-04	1.1e-03	NA	3.0e-03
9	TCGA	Rectum Adenocarcinoma	0.3470	0.1580	5.1e-03	0.023	0.108	0.109	NA	0.036	9.7e-02	1.7e-03	1.7e-03	NA	4.9e-02
10	TCGA	Thyroid Carcinoma	0.1620	0.0710	4.4e-08	0.101	0.090	0.085	NA	0.097	5.3e-10	4.2e-09	1.2e-08	NA	1.0e-09

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10
Shortness of breath walking on level ground	5.0	5.9	13.9	0.0	-3.7	-3.1	-2.6	-2.6	0.0	-2.5	-1.6	-1.9	-3.1
Medication: Co-codamol	4.4	5.1	8.5	0.0	-2.8	-2.9	-2.5	-2.5	0.0	-2.4	-1.8	-2.1	-2.8
Heel bone mineral density (BMD) T-score, automated (left)	4.4	9.9	15.8	0.0	3.8	4.0	3.3	3.5	0.0	3.4	3.5	2.9	3.7
Age started oral contraceptive pill	4.0	5.0	9.6	0.0	1.1	2.7	2.4	2.7	0.0	2.7	3.1	2.4	2.4
Current tobacco smoking	3.9	6.4	9.5	0.0	-2.2	-3.1	-3.0	-3.0	0.0	-2.9	-2.4	-2.9	-3.0
Smoking status: Current	3.8	6.1	9.4	0.0	-2.3	-3.1	-2.9	-2.9	0.0	-2.8	-2.4	-2.6	-2.9
Happiness	3.6	4.3	6.7	0.0	-2.0	-2.5	-2.3	-2.6	0.0	-2.5	-1.7	-2.4	-2.6
Pain all over the body in last month	3.1	3.3	5.4	0.0	-2.3	-2.3	-1.9	-2.0	0.0	-1.9	-1.8	-1.7	-2.2
Chronic bronchitis/emphysema (father)	2.9	3.4	5.7	0.0	-0.8	-2.1	-2.4	-2.2	0.0	-2.3	-2.2	-2.0	-2.0
Had menopause	2.9	3.6	5.8	0.0	0.9	2.4	2.1	2.4	0.0	2.4	2.0	2.1	2.2
Noisy workplace	2.9	3.6	6.9	0.0	-1.4	-2.6	-2.4	-2.4	0.0	-2.5	-1.4	-0.7	-2.6
Gout (self-reported)	2.9	4.0	6.8	0.0	1.9	2.2	2.4	2.5	0.0	2.4	0.9	2.6	2.6
Blood Red Count	2.7	25.9	30.7	4.9	4.4	5.5	5.0	5.2	5.0	5.1	5.2	5.4	5.1
Health satisfaction	2.7	3.5	6.4	0.0	-2.4	-2.5	-2.0	-2.2	0.0	-2.1	-1.2	-1.4	-2.5
Mouth/teeth dental problems: Mouth ulcers	2.7	4.2	6.9	0.0	2.0	2.6	2.2	2.3	0.0	2.2	2.5	2.2	2.3
Frequency of tiredness / lethargy in last 2 weeks	2.5	4.0	9.2	0.0	-3.0	-2.6	-2.3	-2.1	0.0	-2.0	-1.4	-1.5	-2.5
Depression (Nagel 2018)	2.4	3.6	5.6	-1.8	-2.4	-2.2	0.0	-1.9	-1.8	-1.8	-2.1	-1.9	-2.0
Fed-up feelings	2.4	4.4	7.5	0.0	-1.7	-2.6	-2.7	-2.5	0.0	-2.5	-1.9	-2.1	-2.5
Medication for hormone replacement therapy	2.1	2.3	6.1	0.0	-0.7	-1.7	-1.6	-1.7	0.0	-1.8	-2.5	-1.7	-1.4
Frequency of unenthusiasm / disinterest in last 2 weeks	2.1	2.7	8.2	0.0	-2.9	-2.0	-1.7	-1.5	0.0	-1.4	-1.8	-1.4	-1.8
Suffer from ‘nerves’	2.1	3.3	6.4	0.0	-1.4	-2.2	-2.5	-2.4	0.0	-2.3	-0.7	-1.4	-2.5
Frequency of depressed mood in last 2 weeks	2.0	2.8	6.2	0.0	-1.6	-2.1	-2.5	-1.9	0.0	-1.8	-1.7	-1.2	-2.0
Impedance of arm (right)	2.0	9.3	15.7	0.0	2.9	4.0	3.5	3.5	0.0	3.5	3.8	2.1	3.6
Number of full sisters	2.0	2.4	5.9	0.0	0.6	-1.9	-2.4	-2.0	0.0	-2.2	-1.6	-0.2	-1.8
Heel bone mineral density (BMD) T-score, automated (right)	1.9	4.4	12.2	0.0	3.5	2.8	1.8	2.1	0.0	2.0	2.0	1.4	2.5
Average weekly champagne plus white wine intake	1.9	2.7	5.9	0.0	1.1	2.1	2.4	2.1	0.0	2.1	1.0	0.5	2.2
Heel T-Score	1.8	14.1	25.0	3.5	5.0	4.3	3.6	3.7	3.5	3.5	2.9	3.0	4.2
Hearing difficulty/problems: Yes	1.8	2.7	5.7	0.0	1.1	1.8	1.7	2.1	0.0	2.1	1.3	2.4	2.0
Financial difficulties in last 2 years	1.8	2.5	5.3	0.0	-2.1	-2.1	-1.4	-1.5	0.0	-1.4	-2.3	-1.2	-1.6
Smoking Status	1.7	4.0	4.7	-2.1	-1.3	-2.1	-2.2	-2.1	-2.1	-2.1	-2.0	-1.9	-2.0
Pack years adult smoking proportion	1.7	2.6	4.3	0.0	-1.8	-2.1	-1.9	-1.9	0.0	-1.8	-1.3	-1.7	-2.0
Comparative body size at age 10	1.7	4.6	12.7	0.0	-3.6	-2.4	-1.8	-2.1	0.0	-1.9	-1.7	-2.8	-2.4
Alcohol intake frequency.	1.7	4.1	7.1	0.0	-2.0	-2.6	-2.3	-2.5	0.0	-2.4	-1.5	-1.7	-2.7
Blood Eosinophil Count	1.6	12.3	18.1	-3.5	-3.0	-4.1	-4.0	-3.8	-3.6	-3.8	-2.0	-2.0	-4.2
Impedance of arm (left)	1.6	7.4	12.7	0.0	3.1	3.6	3.0	3.1	0.0	3.0	3.1	1.7	3.3
Heart disease (mother)	1.6	2.0	3.8	0.0	1.4	1.9	1.6	1.8	0.0	1.8	1.0	0.8	1.9
Financial situation satisfaction	1.6	2.0	4.7	0.0	-2.2	-1.7	-1.0	-1.2	0.0	-1.1	-2.0	-1.7	-1.3
Ulcerative Colitis (UC)	1.5	2.8	4.2	-1.7	-2.0	-1.8	-1.7	-1.8	-1.7	-1.7	-0.6	-1.2	-2.0
Severe depression (siblings)	1.5	1.7	3.3	0.0	-0.3	-1.7	-1.7	-1.8	0.0	-1.8	-0.9	-0.9	-1.7
Prospective memory result	1.5	1.9	5.7	0.0	-2.4	-1.7	-1.1	-1.1	0.0	-1.0	-1.8	-1.4	-1.3
Emphysema/chronic bronchitis	1.5	1.7	3.6	0.0	-1.8	-1.9	-1.1	-1.4	0.0	-1.4	-1.6	-0.6	-1.6
Wears glasses or contact lenses	1.5	1.7	3.4	0.0	1.6	1.8	1.2	1.5	0.0	1.5	1.4	0.4	1.7
Medication: Omeprazole (e.g. Zanprol)	1.5	1.8	4.0	0.0	-1.8	-1.7	-1.3	-1.7	0.0	-1.6	-0.2	-0.9	-2.0
Medication: Ibuprofen (e.g. Nurofen)	1.4	1.7	3.0	0.0	-0.7	-1.5	-1.7	-1.7	0.0	-1.6	-1.3	-1.3	-1.6
Number of children fathered	1.4	1.5	4.7	0.0	-0.3	-1.1	-1.1	-1.2	0.0	-1.2	-2.2	-2.2	-0.7
Medication for pain relief, constipation, heartburn	1.4	2.3	9.7	0.0	3.1	1.7	1.2	1.3	0.0	1.1	1.1	1.5	1.7
Pack years of smoking	1.4	2.0	3.4	0.0	-1.8	-1.9	-1.5	-1.6	0.0	-1.5	-1.1	-1.5	-1.7
Neuroticism (2016)	1.3	1.9	3.2	1.6	0.7	1.6	0.0	1.7	1.7	1.7	0.8	0.5	1.8
Chronotype (morning person)	1.3	3.0	4.3	1.9	1.7	2.1	1.4	1.8	1.9	1.8	1.6	0.8	1.9
Average weekly fortified wine intake	1.3	1.6	4.2	0.0	2.0	1.4	1.4	1.3	0.0	1.2	0.5	1.2	1.6
Tinnitus: Yes, but not now, but have in the past	1.3	1.4	3.0	0.0	-0.3	1.1	1.7	1.4	0.0	1.5	1.4	1.4	1.1
Frequency of tenseness / restlessness in last 2 weeks	1.3	1.9	4.7	0.0	-1.2	-1.7	-2.2	-1.7	0.0	-1.7	-0.9	-0.8	-1.8
Age at first live birth	1.3	2.3	3.8	0.0	1.8	1.9	1.8	1.6	0.0	1.6	1.9	1.2	1.7
Medication: Omeprazole	1.3	1.5	3.5	0.0	-1.8	-1.7	-1.2	-1.5	0.0	-1.4	-0.1	-0.5	-1.9
Forced expiratory volume in 1-second (FEV1), predicted	1.3	2.8	8.6	0.0	-0.4	-2.1	-1.9	-1.9	0.0	-2.0	-2.9	-1.3	-1.5
Osteoporosis (self-reported)	1.3	1.7	3.1	0.0	-0.9	-1.5	-1.6	-1.5	0.0	-1.5	-1.8	-1.3	-1.4
Risk taking	1.3	1.9	4.2	0.0	-0.9	-1.7	-1.9	-1.5	0.0	-1.5	-2.0	-1.1	-1.4
Pain experienced in last month	1.3	2.2	4.8	0.0	2.2	1.9	1.7	1.4	0.0	1.3	1.7	1.4	1.6
Prostate Cancer	1.2	1.7	3.0	1.4	0.7	1.2	1.7	1.4	1.4	1.4	0.8	1.3	1.4
Ulcerative Colitis	1.2	1.8	6.1	0.0	-2.5	0.0	0.0	0.0	0.0	0.0	-1.8	-1.6	-2.4
Qualifications: CSEs or equivalent	1.2	1.6	4.7	0.0	-2.2	-1.6	-1.4	-1.3	0.0	-1.3	-0.8	-0.4	-1.7
Number of full brothers	1.2	1.5	4.8	0.0	-2.2	-1.3	-0.9	-1.3	0.0	-1.1	-0.0	-1.4	-1.6
Medication: Ibuprofen	1.2	1.5	2.8	0.0	-0.5	-1.4	-1.7	-1.6	0.0	-1.6	-1.1	-0.9	-1.6
Handedness (chirality/laterality): Left-handed	1.2	1.5	2.8	0.0	-0.1	-1.5	-1.7	-1.6	0.0	-1.7	-1.2	-0.8	-1.5
Depressed Affect (Nagel 2018)	1.1	2.4	3.3	-1.7	-0.8	-1.7	0.0	-1.8	-1.8	-1.8	-1.4	-1.7	-1.7
Alzheimer’s Disease (including proxy)	1.1	1.7	2.4	-1.3	0.1	-1.3	-1.4	-1.4	-1.4	-1.5	-1.5	-1.2	-1.1
Medication: Simvastatin	1.1	1.6	2.8	0.0	1.4	1.7	1.1	1.5	0.0	1.5	1.3	1.0	1.6
Alcohol intake versus 10 years previously	1.1	1.6	3.9	0.0	-0.6	-1.7	-2.0	-1.6	0.0	-1.7	-0.5	0.1	-1.8
Length of working week for main job	1.1	1.2	2.4	0.0	-0.6	-1.3	-1.3	-1.6	0.0	-1.5	-1.0	-0.8	-1.5
Breastfed as a baby	1.1	1.4	4.1	0.0	2.0	1.0	1.2	1.1	0.0	0.9	0.4	2.0	1.2
Glaucoma (self-reported)	1.1	1.2	3.2	0.0	-1.1	1.1	1.8	1.4	0.0	1.6	0.9	0.5	1.2
Medication: Allopurinol	1.1	1.4	2.6	0.0	1.5	1.4	1.5	1.4	0.0	1.3	0.5	1.1	1.6
Illnesses of father: None of the above (group 1)	1.1	1.4	2.3	0.0	1.4	1.5	1.5	1.2	0.0	1.2	1.4	0.7	1.3
Supplements: Fish oil (including cod liver oil)	1.1	1.4	3.3	0.0	1.3	1.6	1.3	1.6	0.0	1.5	0.3	0.8	1.8
Number of operations (self-reported)	1.1	1.6	4.6	0.0	2.1	1.5	1.2	1.1	0.0	1.0	1.1	1.5	1.3
Myopia	1.1	1.5	3.4	0.0	1.4	1.7	1.3	1.6	0.0	1.5	0.8	0.1	1.9
Irritable Bowel Disease (IBD)	1.0	2.5	3.1	-1.8	-1.5	-1.7	-1.6	-1.7	-1.7	-1.6	-1.0	-1.3	-1.8
Maternal smoking around birth	1.0	1.4	3.0	0.0	-1.7	-1.6	-1.2	-1.2	0.0	-1.1	-1.4	-0.8	-1.4
Medication: Cholesterol lowering	1.0	1.6	4.7	0.0	2.2	1.5	1.0	1.2	0.0	1.1	1.1	1.2	1.5
Reason for reducing amount of alcohol drunk: Health precaution	1.0	1.2	4.7	0.0	2.2	0.9	0.7	0.8	0.0	0.6	0.7	1.9	1.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.0	1.1	2.7	0.0	-0.6	-1.3	-1.3	-1.5	0.0	-1.5	0.2	-0.6	-1.7
Commuting to job workplace: Car/motor vehicle	1.0	1.1	2.6	0.0	-0.5	-1.2	-1.6	-1.4	0.0	-1.4	-0.5	-0.6	-1.4
Medication: Gliclazide	1.0	1.1	4.4	0.0	-2.1	-0.8	-0.3	-0.7	0.0	-0.5	-1.1	-1.9	-0.7
Relative age of first facial hair	0.9	1.9	5.8	0.0	2.4	1.6	1.2	1.4	0.0	1.3	0.6	1.3	1.7
Angina	0.9	1.1	2.3	0.0	-0.1	-1.2	-1.5	-1.4	0.0	-1.4	-0.7	-1.2	-1.3
Mouth/teeth dental problems	0.9	1.4	2.4	0.0	-1.5	-1.5	-1.2	-1.2	0.0	-1.1	-1.2	-1.5	-1.2
Time employed in main current job	0.9	1.0	2.0	0.0	0.6	1.4	1.2	1.2	0.0	1.2	1.1	0.9	1.2
Illnesses of mother	0.9	1.1	2.6	0.0	-1.6	-1.3	-0.8	-1.2	0.0	-1.1	-1.1	-0.7	-1.3
Qualifications: O levels/GCSEs or equivalent	0.9	1.5	3.5	0.0	-1.1	-1.5	-1.3	-1.3	0.0	-1.4	-1.9	-0.8	-1.3
Medication: Blood pressure	0.9	1.8	2.8	0.0	0.5	1.6	1.7	1.6	0.0	1.6	1.6	1.5	1.4
Medication: Bendroflumethiazide	0.9	1.4	2.1	0.0	1.4	1.5	1.3	1.3	0.0	1.2	1.4	1.1	1.3
Unable to work because of sickness or disability	0.9	1.1	2.4	0.0	-1.6	-1.5	-1.4	-1.0	0.0	-1.0	-1.1	-0.1	-1.2
Mean Putamen Volume	0.8	0.9	1.7	-1.0	-1.3	-1.2	0.0	-1.0	-0.9	-0.9	-0.8	-0.8	-1.1
Medication: Levothyroxine sodium	0.8	1.3	9.4	0.0	-3.1	-0.8	-0.3	-0.6	0.0	-0.4	0.5	-1.2	-1.1
Peak expiratory flow (PEF)	0.8	1.9	8.9	0.0	3.0	1.1	0.9	0.8	0.0	0.6	-0.6	2.1	1.4
Arm predicted mass (right)	0.8	3.9	7.3	0.0	-0.6	-2.5	-2.4	-2.5	0.0	-2.6	-2.7	-1.0	-2.3
Age at last live birth	0.8	1.2	2.2	0.0	1.3	1.4	1.5	1.2	0.0	1.2	0.7	0.5	1.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.8	0.9	2.4	0.0	-0.1	1.1	1.5	1.0	0.0	1.1	1.5	-0.3	0.9
Mood swings	0.8	1.4	4.1	0.0	-0.2	-1.5	-2.0	-1.4	0.0	-1.5	-0.9	-0.5	-1.4
Friendships satisfaction	0.8	0.9	2.7	0.0	-1.6	-1.2	-1.1	-1.1	0.0	-0.9	-0.2	-0.8	-1.3
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.8	0.9	3.5	0.0	-1.9	-1.2	-0.9	-0.6	0.0	-0.6	-1.1	-0.6	-0.9
Ever taken oral contraceptive pill	0.8	0.9	1.8	0.0	-0.6	-1.2	-0.9	-1.3	0.0	-1.3	-0.8	-0.5	-1.4
Hypothyroidism (self reported)	0.7	1.6	11.7	-0.3	-3.4	-0.9	-0.2	-0.5	-0.3	-0.3	0.8	0.3	-1.3
Ever had hysterectomy (womb removed)	0.7	0.7	1.6	0.0	0.2	1.1	1.2	1.0	0.0	1.1	1.2	0.3	0.9
Supplements: Zinc	0.7	0.7	5.8	0.0	2.4	0.7	0.3	0.3	0.0	0.2	-0.2	0.3	0.8
Stomach or abdominal pain in last month	0.7	0.9	2.4	0.0	-0.4	-1.2	-1.6	-1.1	0.0	-1.2	-0.7	0.1	-1.2
Hearing difficulty/problems with background noise	0.7	1.2	3.6	0.0	0.6	0.9	1.2	1.4	0.0	1.3	0.3	1.9	1.3
Arm fat-free mass (right)	0.7	3.6	6.9	0.0	-0.5	-2.5	-2.2	-2.4	0.0	-2.6	-2.6	-0.9	-2.2
Qualifications: College or University degree	0.7	2.1	3.9	0.0	1.4	1.8	2.0	1.8	0.0	1.8	1.0	0.8	2.0
Neck or shoulder pain in last month	0.7	1.0	3.1	0.0	-1.7	-1.1	-0.9	-0.8	0.0	-0.7	-1.4	-1.0	-0.9
Angina (self-reported)	0.7	1.0	2.0	0.0	0.2	-1.0	-1.4	-1.3	0.0	-1.4	-0.7	-1.2	-1.1
Overall health rating	0.7	1.6	5.0	0.0	-2.2	-1.7	-1.1	-1.2	0.0	-1.1	-0.5	-0.9	-1.6
Chest pain or discomfort	0.7	1.0	2.1	0.0	-0.8	-1.5	-1.0	-1.1	0.0	-1.1	-1.4	-0.4	-1.2
Qualifications: NVQ or HND or HNC or equivalent	0.7	0.8	4.3	0.0	-2.1	-1.1	-0.2	-0.7	0.0	-0.5	-0.3	-0.9	-1.0
Smoking status: Previous	0.7	1.0	1.9	0.0	0.7	1.2	1.4	1.3	0.0	1.2	0.4	1.0	1.3
Guilty feelings	0.7	1.0	2.0	0.0	0.5	1.3	0.9	1.4	0.0	1.4	1.2	0.6	1.3
Ever depressed for a whole week	0.7	0.9	1.6	0.0	-0.1	-1.1	-1.0	-1.2	0.0	-1.3	-1.1	-0.8	-1.1
Alzheimer’s Disease (in mother)	0.6	0.7	1.2	-0.8	-0.0	-0.8	-0.9	-0.9	-0.8	-0.9	-1.0	-1.1	-0.7
Rheumatoid Arthritis	0.6	0.9	3.8	0.0	-1.9	0.0	0.0	0.0	0.0	0.0	-0.9	-0.8	-1.8
Respiratory disease	0.6	1.4	1.9	-1.0	-1.1	-1.3	-1.1	-1.1	-1.0	-1.1	-1.4	-1.4	-1.1
Type 2 Diabetes (T2D) (2018)	0.6	1.0	3.6	0.8	0.5	1.0	0.9	0.8	0.8	0.8	1.9	1.4	0.6
Heart attack	0.6	0.8	1.7	0.0	0.4	-0.9	-1.3	-1.1	0.0	-1.1	-1.1	-1.1	-0.8
Back pain experienced in last month	0.6	0.9	1.9	0.0	-0.6	-1.2	-1.4	-1.0	0.0	-1.1	-1.3	-0.4	-1.0
Mineral and other dietary supplements	0.6	0.8	2.0	0.0	-1.4	-1.2	-0.8	-1.1	0.0	-1.0	0.1	-0.6	-1.4
Osteoarthritis (self-reported)	0.6	0.7	3.4	0.0	-1.8	-1.1	-0.6	-0.7	0.0	-0.6	0.3	0.0	-1.2
Commuting to job workplace: Cycle	0.6	0.8	1.8	0.0	1.3	1.1	1.0	0.9	0.0	0.9	-0.2	-0.3	1.4
Fasting Glucose	0.5	0.6	4.7	-0.1	-0.1	0.1	0.0	-0.2	-0.1	-0.2	-1.2	-2.2	0.2
Blood White Count	0.5	3.7	7.8	-1.8	-1.1	-1.7	-2.2	-2.0	-1.9	-2.0	-1.5	-2.8	-1.8
Vitamin and mineral supplements	0.5	0.7	1.8	0.0	-0.7	-1.1	-0.8	-1.1	0.0	-1.1	0.3	-0.3	-1.4
Townsend deprivation index at recruitment	0.5	0.7	1.7	0.0	0.0	0.7	1.3	1.1	0.0	1.1	1.0	1.0	0.9
Age when periods started (menarche)	0.5	1.3	2.1	0.0	1.3	1.5	1.2	1.4	0.0	1.3	0.9	1.2	1.4
Bilateral oophorectomy (both ovaries removed)	0.5	0.6	1.1	0.0	-0.7	0.8	1.0	0.9	0.0	1.1	0.8	-0.3	0.8
Diverticular disease/diverticulitis (self-reported)	0.5	0.5	2.6	0.0	1.4	0.4	0.3	0.3	0.0	0.1	0.6	1.6	0.3
Diabetes (self-reported)	0.5	0.8	2.3	0.0	0.1	1.1	1.2	1.0	0.0	1.0	1.5	0.5	0.8
Hair/balding pattern: Pattern 4	0.5	1.1	5.5	0.0	-2.4	-1.2	-0.8	-0.8	0.0	-0.6	-0.4	-1.0	-1.1
Hypothyroidism/myxoedema (self-reported)	0.5	1.0	7.3	0.0	-2.7	-0.5	0.0	-0.4	0.0	-0.1	0.8	-0.6	-0.9
Birth weight	0.5	1.2	3.0	0.0	-0.9	-1.3	-1.1	-1.5	0.0	-1.5	0.2	-0.6	-1.7
Migraine (self-reported)	0.5	0.7	1.4	0.0	0.6	0.9	1.2	1.0	0.0	0.9	0.6	1.0	1.0
Family relationship satisfaction	0.5	0.6	1.1	0.0	-0.9	-0.9	-0.6	-0.9	0.0	-0.8	-0.7	-1.1	-0.9
Illness, injury, bereavement, stress in last 2 years	0.5	0.6	1.1	0.0	1.0	0.9	0.9	0.7	0.0	0.7	1.1	0.6	0.7
High cholesterol (Self-reported)	0.5	0.8	4.8	0.0	2.2	0.9	0.4	0.7	0.0	0.5	0.1	0.7	1.1
Arm fat-free mass (left)	0.5	2.5	4.7	0.0	-0.4	-2.0	-1.8	-2.0	0.0	-2.1	-2.2	-0.9	-1.8
Cholesterol lowering medication	0.5	0.7	1.6	0.0	0.2	1.0	0.9	1.1	0.0	1.1	1.3	1.0	0.9
Impedance of whole body	0.5	2.7	5.4	0.0	2.3	2.1	1.5	1.8	0.0	1.7	1.9	1.3	1.9
Arm predicted mass (left)	0.5	2.6	4.5	0.0	-0.5	-2.1	-1.8	-2.0	0.0	-2.1	-2.1	-0.8	-1.9
Neuroticism (Nagel 2018)	0.4	0.9	1.9	-1.1	-0.3	-1.0	-1.4	-1.0	-1.1	-1.1	-0.6	-0.5	-1.0
Verbal and Numeric Reasoning (VNR)	0.4	1.0	3.0	0.4	1.7	1.3	0.9	0.8	0.6	0.8	-0.4	-0.2	1.4
Breast Cancer	0.4	1.1	3.6	-0.9	0.0	-0.8	-1.2	-1.1	-1.0	-1.1	-0.5	-1.9	-0.9
Lupus	0.4	0.7	1.7	-0.9	-0.3	-0.7	0.0	-1.0	-0.9	-1.0	-0.2	-1.3	-0.9
Average weekly spirits intake	0.4	0.5	3.1	0.0	-1.5	-0.1	-0.3	-0.1	0.0	0.0	-0.1	-1.8	-0.2
Eye problems/disorders: Diabetes related eye disease	0.4	0.4	1.5	0.0	0.2	0.5	0.3	0.6	0.0	0.6	1.0	1.2	0.4
Qualifications: None of the above	0.4	0.8	1.7	0.0	0.5	1.3	0.8	1.1	0.0	1.2	1.1	-0.3	1.2
Hair/balding pattern: Pattern 3	0.4	0.6	1.3	0.0	0.1	-0.7	-1.2	-1.1	0.0	-1.2	-0.5	-0.7	-0.9
Average weekly red wine intake	0.4	0.6	4.0	0.0	2.0	0.2	-0.3	-0.5	0.0	-0.6	-0.7	-0.9	0.1
Loneliness, isolation	0.4	0.5	2.6	0.0	-0.5	-0.3	-0.6	-0.2	0.0	-0.1	-1.2	-1.6	0.0
Commuting to job workplace: Public transport	0.4	0.5	2.5	0.0	0.4	-0.1	-0.1	-0.4	0.0	-0.4	-1.2	-1.6	0.1
Eye problems/disorders: Glaucoma	0.4	0.4	3.8	0.0	-1.9	-0.2	0.5	0.1	0.0	0.3	0.2	0.4	-0.3
Pain type(s) experienced in last month: Hip pain	0.4	0.5	1.0	0.0	-0.1	-0.9	-1.0	-0.8	0.0	-0.9	-0.9	-0.3	-0.8
Basal cell carcinoma (self-reported)	0.4	0.5	1.1	0.0	-0.1	1.0	0.4	1.0	0.0	1.0	0.6	-0.0	1.0
Bipolar Disorder (2018)	0.3	0.4	1.5	0.0	-1.1	0.0	0.0	0.0	0.0	0.0	-1.1	-0.5	-1.2
Intelligence (Savage-Jansen 2018)	0.3	1.0	5.2	0.2	2.3	1.0	0.6	0.6	0.3	0.5	-0.9	-0.6	1.4
Worry (Nagel 2018)	0.3	0.6	1.2	-1.0	0.2	-0.8	0.0	-1.0	-1.0	-1.1	0.1	0.0	-1.0
Major Depression (MDD)	0.3	0.4	1.1	0.0	-0.2	0.8	0.0	1.0	0.0	1.1	-0.2	0.1	1.0
Age at First Birth	0.3	0.5	1.6	0.6	1.3	0.8	0.0	0.6	0.6	0.6	0.5	0.4	0.8
Allergy or Eczema	0.3	0.7	4.0	-0.5	2.0	0.2	0.2	-0.1	-0.4	-0.2	-1.4	0.2	0.5
Cardiovascular Disease	0.3	1.1	4.8	0.4	1.4	0.9	0.6	0.8	0.6	0.8	0.9	2.2	0.9
Number of treatments/medications taken	0.3	0.6	2.0	0.0	-1.4	-1.0	-0.7	-0.6	0.0	-0.6	-0.8	0.2	-0.9
Systolic blood pressure, automated reading	0.3	0.8	3.1	0.0	0.3	0.9	0.7	0.9	0.0	0.8	1.4	1.8	0.6
Diabetes (father)	0.3	0.4	1.6	0.0	0.8	0.4	-0.5	0.2	0.0	0.1	1.2	1.3	0.0
Hand grip strength (right)	0.3	0.9	3.8	0.0	2.0	1.0	0.7	0.8	0.0	0.6	-0.1	1.1	1.2
Relative age voice broke	0.3	0.4	0.9	0.0	-0.0	-0.9	-0.8	-0.8	0.0	-0.9	-0.4	0.2	-0.9
Multivitamins +/- minerals	0.3	0.4	1.6	0.0	1.2	0.3	-0.1	0.1	0.0	0.0	-1.2	-0.5	0.6
Supplements: Glucosamine	0.3	0.3	1.7	0.0	0.5	-0.3	-0.9	-0.4	0.0	-0.5	-1.3	-0.3	-0.1
Hair/balding pattern: Pattern 2	0.3	0.3	0.6	0.0	0.8	0.7	0.7	0.6	0.0	0.6	0.6	0.6	0.6
Had other major operations	0.3	0.4	2.8	0.0	1.7	0.5	0.4	0.1	0.0	-0.0	0.3	0.7	0.4
Ever unenthusiastic/disinterested for a whole week	0.3	0.3	0.7	0.0	-0.5	-0.8	-0.4	-0.8	0.0	-0.8	-0.2	-0.5	-0.9
Medication: Ramipril	0.3	0.4	2.0	0.0	0.3	0.4	0.3	0.3	0.0	0.3	1.4	1.0	0.1
Neuroticism score	0.3	0.6	1.9	0.0	-0.2	-1.0	-1.4	-0.9	0.0	-1.0	-0.5	-0.3	-1.0
Trunk fat-free mass	0.3	1.6	3.8	0.0	-0.4	-1.6	-1.3	-1.5	0.0	-1.6	-2.0	-0.5	-1.4
Father’s age at death	0.3	0.5	1.0	0.0	-0.5	-0.8	-1.0	-0.9	0.0	-0.9	-0.6	-0.3	-0.9
Worrier / anxious feelings	0.3	0.6	3.0	0.0	1.7	0.7	0.4	0.6	0.0	0.4	0.4	1.0	0.7
Falls in the last year	0.3	0.4	2.3	0.0	0.9	-0.3	-0.4	-0.4	0.0	-0.5	-1.5	0.1	0.0
Trunk predicted mass	0.3	1.6	4.0	0.0	-0.3	-1.6	-1.3	-1.5	0.0	-1.6	-2.0	-0.5	-1.4
Birth weight of first child	0.3	0.5	1.4	0.0	-0.7	-0.9	-0.7	-0.9	0.0	-0.9	0.6	0.1	-1.2
Medication: Paracetamol	0.3	0.5	3.9	0.0	-2.0	-0.8	-0.1	-0.2	0.0	-0.2	-0.3	0.0	-0.7
Medication: Amlodipine	0.3	0.4	0.7	0.0	0.6	0.8	0.4	0.8	0.0	0.8	0.7	0.7	0.8
Pulse wave peak to peak time	0.3	0.3	0.7	0.0	0.6	0.6	0.8	0.7	0.0	0.7	-0.2	0.2	0.9
Medication: Blood pressure	0.3	0.5	1.1	0.0	-0.4	-0.9	-1.0	-0.9	0.0	-0.9	-0.0	0.2	-1.0
Comparative height size at age 10	0.3	1.7	2.8	0.0	-0.6	-1.5	-1.5	-1.6	0.0	-1.7	-1.4	-1.6	-1.4
Supplements: Vitamin C	0.3	0.4	1.1	0.0	-1.0	-0.8	-0.3	-0.5	0.0	-0.5	-1.0	-0.4	-0.6
Illnesses of siblings: Diabetes	0.3	0.4	0.9	0.0	-0.0	0.5	0.8	0.9	0.0	0.9	0.5	0.6	0.8
Long-standing illness, disability or infirmity	0.3	0.5	1.6	0.0	-0.3	0.6	0.9	0.8	0.0	0.9	1.3	0.6	0.5
Medication for cholesterol	0.3	0.5	0.9	0.0	-0.9	-0.9	-0.8	-0.8	0.0	-0.7	-0.3	-0.8	-0.9
Number of self-reported non-cancer illnesses	0.3	0.5	1.0	0.0	0.3	0.8	1.0	0.8	0.0	0.8	0.4	0.8	0.8
Miserableness	0.3	0.5	1.0	0.0	-0.1	-0.9	-1.0	-0.8	0.0	-0.8	-1.0	-0.1	-0.8
Medication: Paracetamol	0.3	0.5	3.3	0.0	-1.8	-0.7	-0.3	-0.2	0.0	-0.2	-0.2	0.3	-0.7
Average weekly beer plus cider intake	0.3	0.4	3.1	0.0	-0.8	-0.5	-0.5	0.1	0.0	0.1	-0.1	1.8	-0.3
Diastolic blood pressure, automated reading	0.3	1.0	2.5	0.0	0.6	1.1	0.9	1.1	0.0	1.1	1.6	1.5	0.9
Heart attack/myocardial infarction (self-reported)	0.3	0.4	0.9	0.0	0.7	-0.5	-0.8	-0.6	0.0	-0.7	-1.0	-0.8	-0.3
Heart disease (siblings)	0.3	0.3	1.0	0.0	0.2	0.4	1.0	0.6	0.0	0.6	0.6	0.7	0.5
Alcohol drinker status: Previous	0.3	0.3	2.1	0.0	-1.4	-0.1	0.7	0.3	0.0	0.4	0.2	0.7	-0.1
Bipolar Disorder or Schizophrenia	0.2	0.6	2.1	0.0	-1.3	0.0	0.0	0.0	0.0	0.0	-1.1	-0.8	-1.5
Alzheimer’s Disease (in father)	0.2	0.2	0.5	-0.4	0.7	-0.2	-0.5	-0.5	-0.5	-0.5	-0.5	-0.4	-0.2
Ovarian Cancer	0.2	0.2	1.2	-0.1	-0.9	-0.3	-0.1	-0.3	-0.1	-0.2	-0.1	-1.1	-0.3
Body Mass Index (BMI) (2010)	0.2	0.2	0.4	-0.6	-0.5	-0.5	0.0	-0.5	-0.6	-0.5	-0.2	-0.2	-0.6
Triglycerides	0.2	0.3	0.5	0.5	-0.3	0.5	0.0	0.6	0.6	0.7	0.6	0.4	0.5
Neuroticism	0.2	0.4	0.7	-0.6	-0.7	-0.7	-0.9	-0.6	-0.6	-0.6	-0.1	-0.8	-0.7
Hair Pigment	0.2	7.0	8.2	2.7	2.2	2.9	2.5	2.8	2.7	2.7	2.2	2.8	2.8
Diabetes (mother)	0.2	0.2	0.6	0.0	0.5	0.3	0.7	0.4	0.0	0.4	0.5	0.8	0.3
Taking other prescription medications	0.2	0.3	0.8	0.0	-0.5	0.5	0.9	0.7	0.0	0.7	0.7	0.4	0.5
Hayfever, allergic rhinitis or eczema	0.2	0.4	2.4	0.0	1.6	0.0	0.3	-0.1	0.0	-0.3	-1.3	0.1	0.3
Medication: Atenolol	0.2	0.2	1.1	0.0	1.1	0.0	-0.3	-0.3	0.0	-0.4	0.8	0.4	-0.2
Sitting height	0.2	1.4	6.9	0.0	2.6	1.1	0.8	0.9	0.0	0.7	-0.4	1.1	1.4
Body mass index (BMI)	0.2	1.1	2.2	0.0	-0.7	-1.4	-1.0	-1.4	0.0	-1.4	-0.4	-0.9	-1.5
Waist circumference	0.2	0.8	1.5	0.0	-0.5	-1.2	-0.9	-1.2	0.0	-1.2	-0.6	-0.7	-1.2
Forced vital capacity (FVC)	0.2	0.6	3.1	0.0	1.5	-0.1	-0.4	-0.2	0.0	-0.4	-1.8	0.4	0.3
Hayfever/allergic rhinitis (self-reported)	0.2	0.3	1.7	0.0	0.3	-0.5	-0.0	-0.6	0.0	-0.7	-1.3	-0.5	-0.3
Forced expiratory volume in 1-second (FEV1)	0.2	0.7	3.1	0.0	1.8	-0.0	-0.4	-0.2	0.0	-0.4	-1.6	0.7	0.3
Pulse rate	0.2	0.3	2.2	0.0	-0.3	-0.1	-0.4	-0.2	0.0	-0.1	-0.2	-1.5	-0.1
Qualifications: A levels/AS levels or equivalent	0.2	0.4	1.5	0.0	-0.2	-0.5	-0.6	-0.6	0.0	-0.6	-0.9	-1.2	-0.4
Serious illness, injury or assault of a close relative in last 2 years	0.2	0.3	2.0	0.0	1.4	0.5	0.0	0.2	0.0	0.1	0.0	0.0	0.5
Mouth/teeth dental problems: Dentures	0.2	0.3	1.0	0.0	0.9	0.6	0.5	0.5	0.0	0.4	0.5	1.0	0.5
Depression (self-reported)	0.2	0.3	0.6	0.0	-0.0	-0.5	-0.5	-0.8	0.0	-0.8	-0.0	-0.6	-0.7
Lung cancer (father)	0.2	0.2	1.0	0.0	-1.0	0.2	0.2	0.3	0.0	0.4	0.7	-0.0	0.0
Forced expiratory volume in 1-second (FEV1), Best measure	0.2	0.7	4.3	0.0	1.0	-0.5	-0.6	-0.6	0.0	-0.8	-2.1	-0.4	-0.1
Pulse wave Arterial Stiffness index	0.2	0.2	0.5	0.0	-0.3	-0.4	-0.7	-0.5	0.0	-0.5	0.4	-0.0	-0.7
Mouth/teeth dental problems: Bleeding gums	0.2	0.3	0.7	0.0	-0.3	-0.5	-0.5	-0.6	0.0	-0.6	-0.8	-0.7	-0.5
Blood clot in the leg (DVT)	0.2	0.2	0.9	0.0	-0.3	-0.1	-0.5	-0.4	0.0	-0.4	1.0	-0.6	-0.5
Medication: Ventolin 100micrograms inhaler	0.2	0.3	1.2	0.0	1.0	0.4	0.1	0.4	0.0	0.3	0.6	1.1	0.3
Forced vital capacity (FVC), Best measure	0.2	0.7	4.8	0.0	1.0	-0.4	-0.4	-0.5	0.0	-0.6	-2.2	-0.8	0.1
Exposure to tobacco smoke outside home	0.2	0.3	0.9	0.0	-0.5	0.4	0.9	0.7	0.0	0.8	0.4	0.5	0.5
Worry too long after embarrassment	0.2	0.3	1.0	0.0	0.5	-0.5	-0.6	-0.2	0.0	-0.3	-1.0	0.8	-0.2
Eye problems/disorders: None of the above	0.2	0.2	0.7	0.0	-0.4	-0.5	-0.9	-0.6	0.0	-0.6	0.1	-0.2	-0.7
Mouth/teeth dental problems: Loose teeth	0.2	0.2	0.7	0.0	0.4	0.4	0.5	0.3	0.0	0.3	0.8	0.8	0.2
Medication: Seretide 50 evohaler	0.2	0.2	0.8	0.0	-0.9	0.2	0.8	0.4	0.0	0.5	0.2	-0.4	0.3
Leg fat mass (right)	0.2	0.8	1.8	0.0	-0.1	-1.2	-1.0	-1.3	0.0	-1.4	-0.5	-0.6	-1.2
Had major operations	0.2	0.3	0.8	0.0	0.6	0.6	0.5	0.5	0.0	0.5	0.4	0.9	0.5
Illnesses of father: Heart disease	0.2	0.2	0.8	0.0	-0.8	-0.6	-0.1	-0.1	0.0	-0.2	-0.9	0.6	-0.3
Whole body fat-free mass	0.2	1.3	3.3	0.0	-0.1	-1.5	-1.2	-1.4	0.0	-1.5	-1.8	-0.6	-1.2
Ever had bowel cancer screening	0.2	0.3	0.9	0.0	-1.0	-0.7	-0.3	-0.5	0.0	-0.5	-0.1	-0.4	-0.7
Eye problems/disorders: Cataract	0.2	0.2	0.8	0.0	-0.9	-0.5	0.2	-0.4	0.0	-0.3	-0.7	-0.5	-0.4
Asthma (self-reported)	0.2	0.4	0.7	0.0	-0.7	-0.8	-0.8	-0.6	0.0	-0.6	-0.8	0.1	-0.7
Whole body water mass	0.2	1.3	3.3	0.0	-0.1	-1.5	-1.2	-1.5	0.0	-1.6	-1.8	-0.5	-1.2
Alcohol drinker status: Never	0.2	0.2	0.7	0.0	-0.2	-0.5	-0.8	-0.4	0.0	-0.5	-0.5	-0.2	-0.4
Ever smoked	0.2	0.3	0.8	0.0	0.6	0.7	0.8	0.6	0.0	0.6	-0.5	-0.4	0.9
Basal metabolic rate	0.2	1.1	2.2	0.0	0.0	-1.3	-1.1	-1.4	0.0	-1.5	-1.5	-0.6	-1.2
Leg fat mass (left)	0.2	0.8	1.8	0.0	0.1	-1.2	-1.0	-1.3	0.0	-1.4	-0.6	-0.6	-1.2
Schizophrenia (2018)	0.1	0.3	1.0	0.0	-0.8	0.0	0.0	0.0	0.0	0.0	-0.7	-0.7	-1.0
Crohns Disease (2017)	0.1	0.2	0.3	-0.6	-0.1	-0.4	-0.5	-0.4	-0.5	-0.4	-0.6	-0.3	-0.3
Reaction Time	0.1	0.1	0.6	0.5	-0.8	0.0	-0.0	0.2	0.4	0.3	0.2	-0.3	0.1
Crohns Disease (2012)	0.1	0.2	0.8	0.0	-0.9	0.0	0.0	0.0	0.0	0.0	-0.6	-0.7	-0.9
Schizophrenia (2014)	0.1	0.3	1.3	0.0	-0.6	0.0	0.0	0.0	0.0	0.0	-1.0	-0.7	-1.1
BMI	0.1	0.3	0.5	-0.7	0.4	-0.4	-0.5	-0.6	-0.7	-0.7	0.3	0.5	-0.7
Height	0.1	2.1	6.3	-1.8	2.5	-0.8	-0.9	-1.0	-1.6	-1.3	-2.1	0.2	-0.3
Waist Hip Ratio (WHR)	0.1	0.2	1.1	0.3	-0.2	0.2	-0.1	0.4	0.4	0.4	-1.1	-0.4	0.6
Systolic Blood Pressure	0.1	0.5	4.3	-0.4	0.1	-0.1	-0.5	-0.1	-0.3	-0.2	0.6	2.1	-0.4
Lung FEV1/FVC ratio	0.1	0.7	4.4	-0.0	-0.5	-0.1	0.3	0.1	0.1	0.1	1.3	2.1	-0.4
Lung FVC	0.1	0.4	2.3	-0.4	-0.8	-0.4	-0.2	-0.2	-0.3	-0.2	-1.5	-0.7	-0.1
Hand grip strength (left)	0.1	0.4	2.0	0.0	1.4	0.5	0.5	0.3	0.0	0.2	0.2	0.8	0.5
Other serious medical condition/disability diagnosed by doctor	0.1	0.1	0.4	0.0	-0.7	0.1	0.3	0.3	0.0	0.4	-0.0	0.1	0.2
Ever used hormone-replacement therapy (HRT)	0.1	0.1	0.5	0.0	-0.7	-0.2	0.0	-0.3	0.0	-0.3	0.3	-0.4	-0.4
Medication: Metformin	0.1	0.1	0.8	0.0	-0.2	-0.2	-0.4	-0.3	0.0	-0.3	-0.3	-0.9	-0.2
Trunk fat percentage	0.1	0.3	2.0	0.0	1.4	0.4	0.3	-0.0	0.0	-0.1	1.1	0.2	0.1
High blood pressure (mother)	0.1	0.2	1.0	0.0	0.7	-0.2	-0.6	-0.2	0.0	-0.3	-1.0	0.2	0.1
Leg predicted mass (left)	0.1	0.3	1.0	0.0	0.6	-0.6	-0.4	-0.7	0.0	-0.8	-1.0	-0.4	-0.4
Trunk fat mass	0.1	0.2	1.7	0.0	1.3	-0.1	-0.1	-0.4	0.0	-0.5	0.4	0.1	-0.2
Number of incorrect matches in round	0.1	0.1	0.9	0.0	-0.9	-0.1	-0.3	-0.1	0.0	-0.0	-0.0	-0.6	-0.2
Past tobacco smoking	0.1	0.2	0.6	0.0	-0.5	-0.5	-0.6	-0.5	0.0	-0.5	0.5	-0.1	-0.7
Alcohol usually taken with meals	0.1	0.1	0.9	0.0	0.4	-0.0	0.1	-0.3	0.0	-0.3	0.2	-0.9	-0.2
Nervous feelings	0.1	0.3	1.3	0.0	-1.1	-0.5	-0.3	-0.3	0.0	-0.3	0.5	0.4	-0.7
Allergy	0.1	0.2	1.2	0.0	-0.5	0.4	-0.0	0.4	0.0	0.4	1.1	0.1	0.2
Fluid intelligence score	0.1	0.2	1.4	0.0	0.6	0.2	0.0	-0.2	0.0	-0.2	-0.7	-1.2	0.2
Illnesses of siblings	0.1	0.2	0.8	0.0	0.7	0.0	-0.6	-0.3	0.0	-0.4	-0.9	-0.4	0.0
Weight	0.1	0.7	1.6	0.0	0.4	-1.0	-0.8	-1.2	0.0	-1.3	-0.7	-0.5	-1.0
Arm fat percentage (right)	0.1	0.3	2.1	0.0	0.9	0.4	0.5	0.1	0.0	0.1	1.4	0.3	0.1
Hip circumference	0.1	0.3	0.8	0.0	0.6	-0.6	-0.4	-0.8	0.0	-0.9	-0.2	-0.4	-0.7
Asthma	0.1	0.1	0.4	0.0	-0.0	-0.3	-0.4	-0.2	0.0	-0.2	-0.6	0.6	-0.2
Medication: Lansoprazole	0.1	0.1	0.7	0.0	-0.4	0.0	0.3	-0.0	0.0	0.0	0.1	-0.9	0.0
Standing height	0.1	0.9	6.6	0.0	2.6	0.7	0.4	0.4	0.0	0.1	-0.7	0.8	0.9
Exposure to tobacco smoke at home	0.1	0.1	0.4	0.0	0.3	-0.1	-0.6	-0.2	0.0	-0.2	-0.6	-0.1	-0.0
Tense / ‘highly strung’	0.1	0.2	1.1	0.0	0.2	-0.3	-0.5	-0.1	0.0	-0.2	0.7	1.0	-0.3
Seen doctor (GP) for nerves, anxiety, tension or depression	0.1	0.1	0.7	0.0	0.8	0.1	0.2	0.1	0.0	0.1	-0.4	-0.1	0.4
Loud music exposure frequency	0.1	0.1	0.8	0.0	0.7	0.0	-0.2	0.1	0.0	0.0	-0.2	0.9	0.1
Headache pain in last month	0.1	0.1	0.4	0.0	-0.7	-0.0	0.1	0.2	0.0	0.2	-0.5	-0.4	0.1
Medication for cholesterol, blood pressure or diabetes	0.1	0.1	0.7	0.0	-0.3	-0.1	0.1	-0.0	0.0	-0.0	-0.8	-0.7	0.1
Body fat percentage	0.1	0.2	0.6	0.0	0.8	-0.2	-0.2	-0.5	0.0	-0.6	0.6	-0.2	-0.5
Leg fat percentage (right)	0.1	0.5	1.2	0.0	-0.1	-0.9	-0.8	-1.1	0.0	-1.1	0.1	-0.4	-1.1
Seen a psychiatrist for nerves, anxiety, tension or depression	0.1	0.1	0.3	0.0	0.5	0.3	0.3	0.3	0.0	0.3	0.0	0.3	0.4
Wheeze or whistling in the chest in last year	0.1	0.3	1.0	0.0	-0.6	-0.8	-0.3	-0.4	0.0	-0.4	-1.0	-0.1	-0.4
Mean time to correctly identify matches	0.1	0.2	0.4	0.0	-0.7	0.3	0.4	0.6	0.0	0.7	0.4	0.5	0.4
Whole body fat mass	0.1	0.2	0.6	0.0	0.6	-0.5	-0.4	-0.7	0.0	-0.8	0.1	-0.1	-0.6
Pulse rate, automated reading	0.1	0.4	1.9	0.0	-1.4	-0.1	-0.1	-0.1	0.0	0.1	0.8	-1.2	-0.3
Leg pain on walking	0.1	0.2	1.6	0.0	-1.2	-0.3	0.0	0.1	0.0	0.1	-0.1	0.1	-0.2
Knee pain experienced in last month	0.1	0.1	0.6	0.0	0.8	-0.1	-0.2	-0.1	0.0	-0.2	-0.6	0.1	0.0
Leg fat-free mass (right)	0.1	0.3	1.4	0.0	0.6	-0.6	-0.3	-0.7	0.0	-0.8	-1.2	-0.4	-0.4
Arm fat percentage (left)	0.1	0.2	1.1	0.0	1.0	0.2	0.3	-0.1	0.0	-0.2	1.1	0.1	-0.1
Diabetes diagnosed by doctor	0.1	0.2	1.3	0.0	-0.6	0.2	0.3	0.2	0.0	0.2	1.1	0.1	-0.1
Ever had stillbirth, spontaneous miscarriage or termination	0.1	0.1	0.4	0.0	-0.2	-0.6	-0.3	-0.4	0.0	-0.4	-0.6	-0.0	-0.4
Qualifications: nursing, teaching	0.1	0.1	0.4	0.0	0.6	0.2	-0.1	0.2	0.0	0.1	0.2	0.6	0.2
Commuting to job workplace: Walk	0.1	0.1	0.3	0.0	0.3	0.5	0.5	0.3	0.0	0.3	-0.3	-0.5	0.5
Breast cancer (self-reported)	0.1	0.2	0.6	0.0	0.8	0.5	0.6	0.4	0.0	0.3	-0.1	0.2	0.6
Medication: Aspirin	0.1	0.1	0.2	0.0	-0.0	0.4	0.3	0.4	0.0	0.4	0.3	-0.0	0.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.1	0.3	0.8	0.0	0.9	-0.4	-0.2	-0.5	0.0	-0.6	-0.8	0.5	-0.2
Leg predicted mass (right)	0.1	0.4	1.6	0.0	0.5	-0.6	-0.4	-0.7	0.0	-0.8	-1.3	-0.5	-0.4
Hearing aid user	0.1	0.1	1.0	0.0	-0.4	-0.5	-0.1	-0.2	0.0	-0.2	-1.0	0.0	-0.2
Mother’s age at death	0.1	0.1	0.4	0.0	0.7	0.4	0.4	0.4	0.0	0.3	-0.0	0.4	0.5
Tinnitus: Yes, now most or all of the time	0.1	0.2	0.4	0.0	-0.6	-0.6	-0.3	-0.4	0.0	-0.4	-0.2	-0.1	-0.6
Medication: Lisinopril	0.1	0.1	0.7	0.0	-0.5	-0.2	0.0	-0.1	0.0	-0.1	0.8	0.5	-0.4
Medication: Atorvastatin	0.1	0.2	0.9	0.0	-0.4	-0.3	-0.1	-0.3	0.0	-0.3	-0.5	-0.9	-0.3
Leg fat percentage (left)	0.1	0.5	1.1	0.0	0.2	-0.9	-0.7	-1.0	0.0	-1.1	-0.2	-0.4	-1.0
Irritability	0.1	0.1	0.5	0.0	-0.7	-0.4	-0.4	0.0	0.0	0.0	-0.2	0.3	-0.2
Ever had prostate specific antigen (PSA) test	0.1	0.1	0.6	0.0	0.8	-0.0	-0.0	-0.1	0.0	-0.2	-0.4	0.6	0.0
Fractured/broken bones in last 5 years	0.1	0.1	0.2	0.0	-0.2	-0.2	-0.3	-0.4	0.0	-0.4	0.1	-0.4	-0.4
Supplements: Calcium	0.1	0.1	0.8	0.0	0.9	-0.1	-0.5	-0.1	0.0	-0.2	-0.4	0.4	0.1
Deep venous thrombosis (DVT) (self-reported)	0.1	0.2	1.0	0.0	-0.0	0.0	-0.4	-0.3	0.0	-0.2	1.0	-0.6	-0.3
Schizophrenia vs Biploar Disorder	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	-0.2	0.0
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Coronary Artery Disease (CAD)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
HbA1C	0.0	0.0	0.1	-0.1	0.2	-0.1	0.0	-0.1	-0.1	-0.2	-0.2	-0.3	-0.1
HDL Cholesterol	0.0	0.1	0.6	-0.0	0.8	0.1	0.0	-0.1	-0.1	-0.2	0.4	-0.0	-0.0
LDL Cholesterol	0.0	0.1	0.3	0.0	0.4	0.0	0.0	-0.2	-0.1	-0.2	0.5	-0.5	-0.1
Primary Biliary Cirrhosis	0.0	0.0	0.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.3	-0.0	0.6
Type 2 Diabetes (T2D) (2012)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Blood Platelet Count	0.0	0.4	2.3	0.0	1.5	0.8	0.2	0.3	0.1	0.2	0.4	0.8	0.5
Tanning	0.0	0.2	0.6	-0.0	0.7	-0.0	0.8	-0.1	-0.1	-0.1	-0.3	-0.7	0.1
Sensitivity / hurt feelings	0.0	0.1	0.3	0.0	0.5	0.0	-0.6	0.1	0.0	-0.0	-0.4	0.1	0.2
Impedance of leg (right)	0.0	0.1	0.7	0.0	0.2	0.1	-0.3	-0.0	0.0	-0.1	0.8	0.5	-0.2
Leg fat-free mass (left)	0.0	0.3	0.8	0.0	0.5	-0.5	-0.3	-0.6	0.0	-0.7	-0.9	-0.3	-0.4
Serious illness, injury or assault to yourself	0.0	0.1	0.4	0.0	0.3	-0.1	0.1	0.0	0.0	-0.0	-0.1	0.6	0.0
High blood pressure	0.0	0.1	0.4	0.0	0.1	0.1	0.1	0.2	0.0	0.2	0.4	0.6	0.0
Impedance of leg (left)	0.0	0.1	0.5	0.0	0.2	-0.3	-0.7	-0.4	0.0	-0.5	0.1	0.2	-0.5
Number of live births	0.0	0.0	0.2	0.0	0.0	0.3	0.4	0.1	0.0	0.2	0.4	0.1	0.1
Arm fat mass (right)	0.0	0.2	0.5	0.0	0.7	-0.2	-0.1	-0.5	0.0	-0.5	0.6	-0.0	-0.5
Pulse wave reflection index	0.0	0.1	0.5	0.0	0.1	0.0	-0.0	0.1	0.0	0.0	-0.1	0.7	0.0
Ever highly irritable/argumentative for 2 days	0.0	0.1	0.2	0.0	-0.3	-0.2	-0.3	-0.3	0.0	-0.3	0.1	-0.0	-0.4
Chronic bronchitis/emphysema (mother)	0.0	0.0	0.0	0.0	0.2	-0.0	-0.2	0.0	0.0	0.0	-0.2	-0.2	0.1
High blood pressure (siblings)	0.0	0.0	0.3	0.0	0.0	-0.2	0.0	-0.1	0.0	-0.1	-0.6	-0.3	0.0
Medication: Aspirin	0.0	0.0	0.2	0.0	0.1	0.3	0.0	0.2	0.0	0.2	0.5	-0.1	0.2
Hypertension (Self-reported)	0.0	0.0	0.3	0.0	0.0	-0.1	-0.0	-0.0	0.0	-0.1	0.4	0.5	-0.2
Arm fat mass (left)	0.0	0.2	0.5	0.0	0.7	-0.3	-0.2	-0.6	0.0	-0.6	0.2	-0.2	-0.5
Illnesses of father: High blood pressure	0.0	0.1	0.2	0.0	-0.1	0.2	0.4	0.3	0.0	0.3	-0.1	0.0	0.3
Vascular/heart problems diagnosed by doctor	0.0	0.1	0.4	0.0	-0.2	0.0	0.1	-0.0	0.0	0.0	-0.4	-0.6	0.1

Hub : Genes

PGA3

Models

Trait associations