TWAS hub - PINLYP

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.2470	0.0560	1.1e-07	0.064	NA	0.102	NA	0.120	6.3e-06	NA	1.0e-08	NA	5.0e-10
2	GTEx	Adipose Visceral Omentum	0.1690	0.0530	3.6e-04	0.097	NA	0.086	NA	0.091	9.8e-06	NA	3.2e-05	NA	1.8e-05
3	GTEx	Artery Aorta	0.2860	0.0660	1.0e-06	0.105	NA	0.135	NA	0.153	2.2e-06	NA	7.2e-08	NA	8.6e-09
4	GTEx	Artery Tibial	0.2642	0.0446	1.1e-15	0.227	NA	0.240	NA	0.248	9.4e-18	NA	8.9e-19	NA	2.1e-19
5	GTEx	Brain Cerebellar Hemisphere	0.3340	0.0960	4.0e-04	0.202	NA	0.153	NA	0.180	6.6e-06	NA	9.8e-05	NA	2.2e-05
6	GTEx	Brain Cerebellum	0.2680	0.0800	6.2e-04	0.283	NA	0.181	NA	0.270	5.1e-09	NA	5.0e-06	NA	1.3e-08
7	GTEx	Brain Nucleus accumbens basal ganglia	0.2650	0.0930	8.4e-03	0.154	NA	0.074	NA	0.132	6.7e-05	NA	4.9e-03	NA	2.1e-04
8	GTEx	Brain Putamen basal ganglia	0.4600	0.1050	2.3e-04	0.139	NA	0.176	NA	0.252	3.5e-04	NA	5.9e-05	NA	1.1e-06
9	GTEx	Breast Mammary Tissue	0.2040	0.0550	1.8e-05	0.056	NA	0.108	NA	0.110	7.7e-04	NA	3.6e-06	NA	2.9e-06
10	GTEx	Breast Mammary Tissue (Male)	0.3421	0.1035	1.3e-03	0.059	NA	0.071	NA	0.062	1.7e-02	NA	1.0e-02	NA	1.5e-02
11	GTEx	Breast Mammary Tissue (Female)	0.0973	0.0825	1.4e-01	0.000	NA	-0.008	NA	0.004	3.3e-01	NA	6.4e-01	NA	2.3e-01
12	GTEx	Cells Transformed fibroblasts	0.2920	0.0520	1.4e-13	0.133	NA	0.117	NA	0.214	3.5e-10	NA	4.5e-09	NA	5.1e-16
13	GTEx	Colon Sigmoid	0.3870	0.0840	2.1e-06	0.134	NA	0.167	NA	0.238	1.9e-05	NA	1.6e-06	NA	6.5e-09
14	GTEx	Colon Transverse	0.2090	0.0640	3.3e-04	0.013	NA	0.057	NA	0.046	7.7e-02	NA	1.1e-03	NA	3.2e-03
15	GTEx	Esophagus Gastroesophageal Junction	0.2540	0.0730	1.2e-04	0.039	NA	0.095	NA	0.132	1.5e-02	NA	2.5e-04	NA	1.8e-05
16	GTEx	Esophagus Mucosa	0.2270	0.0580	8.9e-07	0.167	NA	0.123	NA	0.164	2.6e-11	NA	1.4e-08	NA	4.1e-11
17	GTEx	Esophagus Muscularis	0.1980	0.0510	1.0e-05	0.119	NA	0.143	NA	0.144	1.1e-07	NA	5.4e-09	NA	4.7e-09
18	GTEx	Heart Atrial Appendage	0.2160	0.0650	1.6e-04	-0.001	NA	0.065	NA	0.015	3.7e-01	NA	7.3e-04	NA	6.5e-02
19	GTEx	Lung	0.2354	0.0516	6.2e-09	0.131	NA	0.190	NA	0.185	3.1e-10	NA	1.7e-14	NA	3.9e-14
20	GTEx	Muscle Skeletal	0.0975	0.0311	2.2e-04	0.004	NA	0.017	NA	0.011	1.2e-01	NA	7.4e-03	NA	2.8e-02
21	GTEx	Nerve Tibial	0.3297	0.0530	1.7e-13	0.123	NA	0.234	NA	0.255	5.1e-09	NA	1.4e-16	NA	4.0e-18
22	GTEx	Ovary	0.3640	0.0830	2.4e-05	0.254	NA	0.262	NA	0.314	6.0e-07	NA	3.8e-07	NA	1.8e-08
23	GTEx	Pancreas	0.2720	0.0740	5.9e-05	0.151	NA	0.137	NA	0.145	6.3e-07	NA	2.3e-06	NA	1.1e-06
24	GTEx	Skin Sun Exposed Lower leg	0.1730	0.0400	2.8e-09	0.165	NA	0.154	NA	0.170	1.4e-13	NA	9.4e-13	NA	4.9e-14
25	GTEx	Thyroid	0.1430	0.0360	1.3e-06	0.078	NA	0.086	NA	0.113	1.4e-06	NA	4.2e-07	NA	6.1e-09

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25
Forced expiratory volume in 1-second (FEV1), predicted	4.8	9.9	16.3	-3.7	-3.3	-3.2	-3.2	-3.8	-3.7	-3.3	-3.1	-2.9	-1.0	-1.9	-2.4	-4.0	-3.0	-3.3	-3.3	-3.2	-1.8	-3.5	-3.1	-4.0	-3.9	-2.1	-2.7	-3.3
Height	4.6	89.0	141.6	-11.5	-11.3	-9.4	-7.3	-11.9	-10.8	-11.0	-9.4	-10.2	-4.0	-5.0	-6.9	-10.3	-8.9	-9.9	-10.8	-8.9	-6.0	-11.0	-8.6	-11.4	-10.9	-5.3	-9.4	-9.4
Eye problems/disorders: Diabetes related eye disease	4.2	4.6	7.8	-2.5	-2.0	-2.1	-1.8	-2.6	-2.5	-2.4	-2.8	-2.4	-1.5	-2.0	-1.7	-2.0	-1.4	-2.5	-2.2	-2.5	-0.8	-1.9	-2.3	-1.9	-2.2	-2.0	-2.0	-2.4
Standing height	4.2	41.9	61.9	-7.8	-7.8	-6.5	-5.1	-7.8	-7.3	-7.4	-6.8	-7.0	-3.3	-3.9	-4.7	-7.2	-6.4	-6.8	-7.4	-6.3	-2.9	-7.6	-6.1	-7.9	-7.5	-3.8	-6.3	-6.1
Heart disease (siblings)	4.2	5.1	9.8	2.4	2.7	1.9	2.0	3.1	2.7	2.6	2.7	2.5	1.3	1.8	1.6	2.5	1.7	2.5	2.3	2.4	0.9	2.3	2.4	2.3	2.4	2.0	2.0	2.3
Ulcerative Colitis	4.1	6.0	10.8	2.5	1.5	2.5	3.0	2.8	2.1	1.9	2.3	2.8	1.4	1.9	2.9	3.3	3.0	2.9	1.9	2.7	0.5	2.3	2.9	2.7	2.8	1.8	1.1	3.0
Trunk predicted mass	3.9	22.3	34.5	-5.9	-4.2	-5.8	-4.6	-4.7	-4.0	-4.3	-5.4	-5.7	-4.1	-4.5	-4.0	-5.0	-5.3	-5.1	-4.0	-5.6	-1.0	-4.8	-5.1	-5.2	-4.6	-4.4	-2.6	-5.3
Trunk fat-free mass	3.8	21.8	33.6	-5.8	-4.2	-5.7	-4.5	-4.7	-4.0	-4.3	-5.3	-5.6	-4.0	-4.4	-4.0	-5.0	-5.2	-5.0	-4.0	-5.5	-0.9	-4.7	-5.0	-5.1	-4.5	-4.3	-2.7	-5.2
Blood White Count	3.7	27.1	55.5	-4.5	-1.7	-5.5	-7.5	-6.3	-1.7	-2.0	-4.5	-5.5	-7.0	-5.0	-6.2	-6.6	-7.5	-5.0	-1.6	-5.2	0.7	-3.9	-7.4	-6.5	-5.0	-4.6	-0.0	-6.8
Forced vital capacity (FVC)	3.7	14.4	22.1	-3.8	-3.3	-3.7	-3.9	-3.6	-3.3	-3.4	-4.7	-4.6	-3.0	-3.9	-3.3	-4.4	-3.4	-4.2	-3.5	-4.3	-2.3	-3.3	-4.6	-4.2	-4.2	-3.7	-2.4	-4.4
Peak expiratory flow (PEF)	3.7	8.7	14.1	-2.7	-2.2	-3.0	-3.2	-2.0	-1.8	-2.1	-3.7	-3.6	-3.2	-3.7	-3.2	-2.7	-2.8	-3.5	-2.0	-3.7	-2.9	-2.6	-3.6	-2.3	-2.5	-3.6	-0.7	-3.8
Heel T-Score	3.6	28.3	37.3	6.0	4.0	6.1	5.8	4.9	3.9	4.8	6.1	5.7	5.8	4.9	5.4	5.3	5.3	6.0	4.5	5.9	5.4	5.3	5.8	5.3	5.2	5.0	2.9	6.1
Multivitamins +/- minerals	3.5	4.4	6.8	-2.1	-2.1	-2.1	-2.2	-2.2	-2.3	-2.0	-2.5	-2.4	-1.6	-2.0	-2.2	-2.2	-1.9	-2.5	-1.8	-2.5	-1.9	-1.8	-2.4	-1.9	-1.7	-1.5	-1.5	-2.6
Fluid intelligence score	3.2	6.6	11.3	-2.4	-2.5	-2.2	-2.6	-2.5	-2.4	-2.6	-3.3	-3.0	-3.4	-2.8	-2.0	-2.8	-1.6	-3.0	-2.3	-3.0	-1.2	-2.1	-3.1	-1.9	-2.7	-3.0	-1.4	-3.0
Forced expiratory volume in 1-second (FEV1)	3.2	10.6	17.6	-3.1	-2.7	-3.1	-3.3	-2.7	-2.5	-2.8	-4.2	-4.0	-2.9	-3.7	-3.1	-3.7	-2.9	-3.6	-3.0	-3.7	-2.6	-2.8	-3.9	-3.3	-3.5	-3.4	-1.8	-3.9
Illnesses of father: Heart disease	3.2	4.5	11.7	2.8	2.9	1.9	1.2	3.4	3.0	3.0	1.8	1.7	1.0	0.4	1.1	1.8	1.2	2.2	2.9	1.8	2.4	2.0	1.4	2.1	2.1	0.4	2.7	1.9
Ulcerative Colitis (UC)	3.1	5.8	12.2	2.1	0.8	2.6	3.5	1.9	0.9	1.2	2.3	2.7	2.5	2.5	3.4	2.8	2.9	2.8	1.1	2.7	1.5	1.9	3.2	2.4	2.4	2.6	0.1	3.4
Verbal and Numeric Reasoning (VNR)	3.0	7.1	14.1	-2.0	-1.8	-2.3	-3.3	-2.0	-1.7	-1.8	-3.4	-3.1	-3.8	-3.5	-2.9	-3.0	-2.0	-3.0	-1.7	-3.2	-1.4	-1.6	-3.5	-1.9	-2.7	-3.6	-0.5	-3.3
Birth weight of first child	3.0	5.4	8.2	-2.4	-2.6	-1.9	-1.9	-2.7	-2.5	-2.5	-2.5	-2.5	-2.1	-1.7	-2.1	-2.6	-2.1	-2.7	-2.6	-2.4	-0.3	-2.5	-2.4	-2.5	-2.9	-2.2	-1.9	-2.2
Commuting to job workplace: Car/motor vehicle	3.0	3.5	9.8	1.9	2.5	1.0	0.5	2.7	2.8	3.0	1.6	1.3	-0.4	-0.1	0.4	1.9	0.5	1.6	3.1	1.0	2.0	2.2	1.1	2.3	1.9	-0.3	3.1	1.0
Intelligence (Savage-Jansen 2018)	2.9	8.9	19.5	-2.0	-0.7	-3.0	-4.4	-1.1	-0.5	-0.7	-3.4	-3.1	-4.1	-4.3	-4.2	-2.9	-3.2	-3.4	-0.5	-3.5	-1.9	-1.9	-4.0	-2.4	-2.5	-4.4	1.0	-3.9
Comparative height size at age 10	2.9	16.2	32.5	-4.8	-5.7	-3.4	-2.7	-5.3	-5.1	-5.3	-3.5	-3.9	-0.5	-0.9	-2.4	-5.0	-3.1	-3.8	-5.2	-3.0	-2.5	-4.7	-3.3	-5.2	-5.1	-0.9	-5.0	-3.5
Allergy or Eczema	2.8	7.5	16.9	-2.1	-1.9	-2.2	-3.6	-1.9	-1.6	-2.0	-3.4	-2.7	-3.3	-3.3	-4.1	-3.4	-1.6	-3.8	-1.7	-3.1	-1.2	-2.6	-3.5	-2.4	-2.5	-2.9	-0.7	-3.3
Ever used hormone-replacement therapy (HRT)	2.8	3.5	8.7	-2.3	-2.9	-1.7	-1.0	-2.4	-2.5	-2.9	-1.4	-1.3	0.2	0.2	-1.0	-1.6	-0.4	-1.8	-2.8	-1.0	-1.9	-2.3	-0.8	-2.0	-2.5	0.4	-3.0	-1.5
Breastfed as a baby	2.8	3.5	6.5	-2.1	-2.0	-2.0	-2.2	-1.4	-1.3	-1.8	-2.5	-1.7	-2.3	-2.2	-2.2	-1.0	-1.2	-2.4	-2.1	-2.4	0.0	-1.0	-2.1	-1.4	-1.8	-1.9	-0.9	-2.5
Whole body fat-free mass	2.8	16.2	26.5	-5.2	-3.6	-5.1	-3.9	-4.1	-3.5	-3.6	-4.5	-4.7	-3.3	-3.6	-3.4	-4.4	-4.7	-4.3	-3.4	-4.7	-0.3	-4.3	-4.2	-4.6	-4.1	-3.6	-2.4	-4.5
Whole body water mass	2.8	15.9	25.9	-5.1	-3.5	-5.0	-3.9	-4.1	-3.4	-3.6	-4.4	-4.7	-3.2	-3.5	-3.4	-4.3	-4.6	-4.2	-3.3	-4.6	-0.3	-4.2	-4.2	-4.5	-4.0	-3.6	-2.3	-4.4
Arm predicted mass (left)	2.8	14.0	22.1	-4.6	-3.0	-4.7	-4.0	-3.7	-3.0	-3.1	-4.1	-4.5	-3.2	-3.5	-3.5	-4.3	-4.3	-4.0	-2.8	-4.4	-0.3	-3.8	-4.2	-4.2	-3.6	-3.5	-1.8	-4.3
Ever had bowel cancer screening	2.7	3.2	8.6	-1.8	-2.7	-1.1	-0.9	-2.2	-2.2	-2.5	-1.8	-1.4	-0.8	-0.6	-1.7	-1.4	-0.8	-2.1	-2.4	-1.2	-2.9	-1.8	-1.4	-1.9	-1.8	-0.5	-2.4	-1.4
Supplements: Zinc	2.6	2.8	4.4	-2.1	-1.7	-2.1	-1.5	-1.6	-2.1	-1.6	-2.1	-1.9	-1.5	-1.7	-1.5	-0.7	-1.6	-2.0	-1.3	-2.1	-1.9	-2.1	-1.5	-1.3	-1.2	-1.2	-1.2	-1.4
Medication: Co-codamol	2.6	3.0	6.2	-1.7	-1.3	-1.4	-2.1	-1.6	-1.1	-1.6	-2.1	-1.8	-1.4	-1.6	-2.0	-2.0	-1.6	-1.9	-1.5	-1.6	-0.6	-1.4	-2.5	-2.4	-2.3	-1.2	-1.1	-2.3
Supplements: Fish oil (including cod liver oil)	2.6	3.5	6.4	-2.0	-1.9	-2.1	-1.8	-1.6	-1.7	-1.8	-2.5	-2.5	-1.6	-2.4	-1.8	-0.9	-1.4	-2.2	-1.4	-2.5	-1.1	-1.4	-2.2	-1.3	-1.2	-2.2	-0.8	-2.2
Alcohol drinker status: Never	2.6	3.2	9.9	2.0	3.1	1.4	1.2	2.0	2.0	2.5	1.7	1.9	1.2	0.6	1.3	1.5	0.8	1.9	2.6	1.3	1.6	1.7	1.4	1.6	2.1	0.6	2.2	1.8
Arm fat-free mass (left)	2.6	13.0	20.3	-4.4	-3.0	-4.5	-3.8	-3.6	-2.9	-3.0	-3.9	-4.2	-3.1	-3.3	-3.4	-4.2	-4.2	-3.9	-2.6	-4.2	-0.3	-3.7	-4.0	-4.2	-3.5	-3.3	-1.8	-4.2
Vitamin and mineral supplements	2.5	3.4	5.4	2.0	1.7	2.2	2.0	1.5	1.8	1.6	2.2	2.1	2.1	1.9	2.1	1.3	1.5	2.3	1.4	2.3	1.9	1.8	1.8	1.2	1.0	1.6	1.0	2.3
Arm predicted mass (right)	2.5	12.6	20.6	-4.5	-2.9	-4.5	-3.7	-3.7	-3.0	-3.1	-3.7	-4.1	-2.8	-3.0	-3.2	-4.1	-4.1	-3.8	-2.7	-4.1	-0.8	-3.9	-3.7	-4.1	-3.6	-3.0	-2.0	-4.0
Illnesses of siblings	2.4	3.3	7.5	-1.7	-2.2	-1.2	-1.6	-2.7	-2.3	-1.9	-2.1	-1.9	-1.4	-1.4	-1.5	-1.9	-1.5	-2.1	-1.5	-1.7	-1.7	-2.0	-2.0	-2.0	-1.8	-1.1	-1.7	-1.8
Forced vital capacity (FVC), Best measure	2.4	8.9	14.4	-2.7	-2.9	-2.6	-2.9	-2.8	-2.7	-2.8	-3.8	-3.5	-2.2	-3.1	-2.6	-3.7	-2.3	-3.3	-3.0	-3.3	-1.5	-2.6	-3.7	-3.4	-3.8	-2.9	-2.1	-3.4
Arm fat-free mass (right)	2.4	12.1	20.3	-4.5	-3.2	-4.4	-3.4	-3.8	-3.2	-3.3	-3.7	-4.0	-2.6	-2.7	-2.8	-4.0	-4.0	-3.6	-2.9	-3.9	-0.6	-3.9	-3.5	-4.1	-3.5	-2.6	-2.4	-3.9
Depression (self-reported)	2.3	2.7	6.9	-1.9	-2.0	-1.3	-1.1	-2.1	-1.9	-2.1	-1.5	-2.1	-0.4	-0.6	-1.1	-2.1	-1.2	-1.7	-2.1	-1.4	0.2	-1.2	-1.6	-2.0	-2.6	-1.0	-1.8	-1.6
Breast Cancer	2.1	5.2	65.4	1.1	0.9	1.6	1.4	0.4	0.4	0.5	2.2	1.5	3.8	2.8	2.2	0.1	1.6	1.7	0.3	2.3	8.1	0.3	1.5	0.3	-0.2	2.4	-0.5	1.7
Diverticular disease/diverticulitis (self-reported)	2.1	2.5	5.9	1.3	1.4	1.4	1.8	1.1	1.2	1.0	2.0	1.9	2.3	2.1	1.0	1.3	1.4	1.5	1.1	2.1	0.7	1.2	2.2	1.1	1.6	2.4	0.3	2.0
Happiness	2.1	2.5	7.8	-1.2	0.6	-2.1	-2.3	0.3	0.2	0.4	-1.4	-1.4	-2.1	-2.2	-2.5	-0.7	-2.8	-1.5	0.4	-1.8	-0.8	-1.4	-1.9	-1.5	-0.7	-1.8	0.9	-2.2
Forced expiratory volume in 1-second (FEV1), Best measure	2.1	6.8	11.3	-2.4	-2.5	-2.2	-2.4	-2.4	-2.4	-2.5	-3.4	-3.0	-2.1	-2.7	-2.2	-3.1	-1.9	-2.8	-2.7	-2.8	-1.7	-2.3	-3.1	-2.8	-3.3	-2.5	-1.9	-3.0
Exposure to tobacco smoke outside home	2.1	2.8	7.0	-2.0	-1.5	-1.5	-1.2	-1.9	-1.8	-1.6	-1.1	-2.0	-0.8	-0.3	-1.0	-2.4	-2.4	-1.4	-1.5	-1.1	-0.6	-2.5	-1.8	-2.6	-1.9	0.3	-1.6	-1.7
Number of full brothers	2.1	2.7	7.5	1.1	2.7	0.2	0.1	2.7	2.4	2.2	1.5	1.7	0.5	0.3	0.5	1.4	0.4	1.4	2.6	0.7	1.8	1.1	1.2	1.6	2.7	0.4	2.5	0.9
Osteoarthritis (self-reported)	2.1	2.7	7.3	1.3	0.8	1.1	1.8	1.2	0.9	1.3	1.9	1.9	2.7	1.5	1.9	1.9	1.3	1.8	1.2	1.4	1.0	1.6	2.3	1.9	2.2	1.1	0.9	2.1
Tinnitus: Yes, now most or all of the time	2.1	2.4	7.1	1.7	2.3	1.1	0.5	2.1	2.2	2.3	1.3	1.1	0.6	-0.0	0.7	1.3	0.4	1.3	2.1	0.7	2.0	2.0	0.9	1.7	2.2	-0.4	2.7	0.5
Basal metabolic rate	2.1	11.7	19.9	-4.5	-3.0	-4.4	-3.3	-3.5	-3.0	-3.1	-3.7	-4.0	-2.7	-3.0	-2.9	-3.8	-4.0	-3.6	-2.8	-4.0	-0.0	-3.7	-3.5	-4.0	-3.4	-3.0	-2.0	-3.8
Ever had hysterectomy (womb removed)	2.0	2.3	9.0	-0.5	-2.7	1.0	1.6	-1.8	-2.3	-2.4	-0.3	0.2	1.5	1.5	1.3	-0.4	2.1	-0.2	-2.0	0.6	-0.8	-0.5	0.6	-0.4	-0.6	2.0	-3.0	1.0
Father’s age at death	1.9	2.6	6.5	-1.6	-2.5	-0.8	-1.0	-2.5	-2.2	-2.2	-1.3	-1.4	-0.1	-0.1	-1.1	-1.8	-0.5	-1.7	-2.3	-0.9	-1.4	-1.3	-1.2	-1.7	-1.9	-0.3	-2.3	-1.7
Birth weight	1.9	4.1	8.3	-2.9	-2.5	-2.5	-1.5	-2.3	-2.0	-2.4	-1.9	-2.1	-0.9	-0.8	-1.3	-2.0	-2.6	-1.9	-2.2	-1.9	-1.0	-2.6	-1.7	-2.5	-2.1	-1.0	-2.0	-1.7
Pulse rate, automated reading	1.9	6.3	11.5	2.5	2.1	2.7	3.0	2.0	1.5	1.9	3.1	2.9	2.1	2.9	2.8	2.6	2.1	2.9	1.9	3.0	1.6	2.0	3.0	2.3	2.5	3.4	0.8	3.0
Arm fat percentage (left)	1.9	7.4	11.6	2.4	2.4	2.3	2.8	2.5	2.3	2.5	3.4	3.1	2.4	2.8	2.8	3.2	2.5	3.2	2.6	2.8	2.4	2.4	3.4	3.0	3.1	2.3	1.8	2.9
Hayfever, allergic rhinitis or eczema	1.8	4.0	11.4	-0.9	-1.0	-1.1	-2.7	-1.0	-0.8	-0.9	-2.5	-1.9	-2.8	-2.7	-3.4	-2.5	-1.1	-2.8	-0.9	-2.1	-1.0	-1.7	-2.7	-1.7	-2.0	-2.5	-0.1	-2.4
Mouth/teeth dental problems	1.7	2.6	5.5	-1.6	-1.2	-2.0	-2.1	-1.2	-1.4	-1.1	-2.3	-1.3	-2.2	-2.3	-1.4	-1.0	-1.3	-1.8	-1.1	-2.3	0.8	-1.2	-2.1	-1.1	-1.4	-1.9	-0.6	-1.8
Pulse rate	1.7	2.9	4.5	1.9	1.7	1.9	1.8	1.9	1.6	1.8	1.8	2.0	0.9	1.2	1.6	2.1	1.7	2.0	1.5	1.7	0.8	1.4	2.0	1.9	2.0	1.6	1.3	2.0
Emphysema/chronic bronchitis	1.7	1.9	3.6	1.3	1.3	1.2	1.7	0.8	1.0	1.1	1.7	1.8	1.4	1.6	1.9	1.1	0.8	1.9	1.2	1.6	1.2	1.3	1.6	1.1	1.3	1.3	0.5	1.9
Mineral and other dietary supplements	1.7	2.3	4.2	1.8	2.0	1.9	1.4	1.4	1.5	1.5	2.0	1.9	1.0	1.8	1.5	0.6	1.3	1.9	1.2	2.0	1.2	1.1	1.7	1.2	0.9	1.4	0.8	2.0
Osteoporosis (self-reported)	1.7	2.2	5.7	-1.5	-0.6	-1.8	-1.8	-0.7	-0.7	-1.2	-2.3	-1.2	-1.4	-2.4	-1.6	-0.6	-0.8	-1.9	-0.9	-2.1	-0.4	-0.7	-1.9	-0.8	-1.3	-2.4	-0.2	-1.8
Hand grip strength (left)	1.6	4.1	8.7	-1.5	-1.5	-1.8	-2.5	-1.5	-1.2	-1.2	-2.5	-2.8	-3.0	-2.5	-2.1	-2.1	-1.8	-2.3	-1.0	-2.4	0.5	-1.7	-2.8	-1.6	-2.2	-2.4	-0.4	-2.5
Average weekly fortified wine intake	1.6	1.9	5.2	1.5	1.7	0.9	0.8	2.3	2.0	1.8	1.6	1.6	0.2	1.0	0.8	1.3	1.0	1.4	1.9	1.5	1.2	1.0	1.4	1.3	1.2	0.7	1.4	1.2
Qualifications: CSEs or equivalent	1.6	2.1	4.4	1.3	0.6	1.7	2.1	0.8	0.2	0.7	1.7	1.5	1.4	2.0	2.1	1.2	1.6	1.8	0.6	1.7	0.1	1.3	1.9	1.4	1.1	2.1	-0.1	1.9
Arm fat percentage (right)	1.6	6.3	9.5	2.3	2.3	2.1	2.6	2.4	2.2	2.4	3.1	2.8	2.2	2.4	2.6	3.0	2.3	3.0	2.4	2.5	2.6	2.4	3.1	2.8	2.9	2.0	1.8	2.6
Bipolar Disorder (2018)	1.5	2.4	5.7	-1.4	-2.4	-0.6	-0.6	-2.1	-1.8	-2.4	-1.4	-1.7	-0.4	-0.3	-0.8	-2.0	-0.7	-1.6	-2.3	-0.9	-0.8	-1.4	-1.4	-1.8	-2.3	-0.7	-2.1	-1.1
HDL Cholesterol	1.5	2.4	3.5	-1.7	-1.7	-1.9	-1.1	-1.9	-1.6	-1.5	-1.8	-1.8	-1.4	-1.2	-1.0	-1.5	-1.9	-1.5	-1.5	-1.8	-1.5	-1.2	-1.7	-1.8	-1.2	-1.4	-1.1	-1.7
Leg predicted mass (left)	1.5	7.7	14.9	-3.8	-2.4	-3.9	-2.7	-2.8	-2.4	-2.4	-2.9	-3.0	-2.0	-2.3	-2.4	-2.9	-3.5	-2.9	-2.2	-3.2	0.5	-3.2	-2.6	-3.4	-2.9	-2.4	-1.7	-3.1
Financial difficulties in last 2 years	1.5	2.1	8.2	-1.5	-0.5	-1.6	-1.6	-0.6	-0.4	-0.5	-1.0	-1.1	-0.1	-0.9	-2.1	-1.9	-2.9	-1.4	-0.4	-1.0	1.6	-1.4	-1.5	-2.4	-1.9	-0.8	-0.3	-1.9
Medication: Ibuprofen (e.g. Nurofen)	1.5	1.9	5.5	1.8	1.8	1.3	0.4	1.9	2.1	2.2	1.0	0.9	-0.7	-0.3	0.0	1.1	0.5	1.0	2.1	0.9	2.1	1.6	0.5	1.4	1.3	-0.2	2.3	0.7
Seen doctor (GP) for nerves, anxiety, tension or depression	1.5	2.3	3.8	-1.5	-1.9	-1.2	-1.3	-1.6	-1.5	-1.6	-1.6	-1.9	-0.4	-1.1	-1.9	-1.5	-1.6	-1.9	-1.4	-1.3	-0.3	-1.2	-1.8	-2.0	-1.8	-1.2	-1.3	-1.9
Alcohol intake frequency.	1.5	3.5	12.3	1.6	3.5	0.5	0.5	2.6	2.9	3.1	1.9	1.6	-0.0	0.3	0.6	1.8	-0.8	1.9	3.1	1.1	0.0	1.3	1.3	1.3	2.5	0.6	3.0	1.3
Leg fat-free mass (right)	1.5	8.2	15.1	-3.9	-2.6	-3.9	-2.7	-3.0	-2.6	-2.5	-2.9	-3.1	-2.1	-2.1	-2.3	-3.3	-3.6	-2.9	-2.3	-3.1	0.3	-3.4	-2.7	-3.6	-3.1	-2.2	-2.0	-3.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.5	3.1	7.3	-1.1	-1.2	-0.9	-2.1	-1.4	-1.2	-1.5	-2.3	-1.7	-0.9	-2.1	-2.0	-2.7	-0.5	-2.1	-1.7	-1.8	-1.0	-0.9	-2.4	-1.8	-2.4	-2.1	-0.9	-2.5
Leg predicted mass (right)	1.5	8.1	14.9	-3.9	-2.5	-3.9	-2.7	-3.0	-2.6	-2.5	-2.9	-3.0	-2.1	-2.1	-2.3	-3.2	-3.6	-2.8	-2.3	-3.1	0.4	-3.4	-2.7	-3.6	-3.1	-2.2	-1.9	-3.1
Leg fat-free mass (left)	1.4	7.6	14.6	-3.8	-2.4	-3.8	-2.7	-2.8	-2.4	-2.4	-2.9	-3.0	-1.9	-2.3	-2.4	-3.0	-3.5	-2.8	-2.2	-3.2	0.6	-3.2	-2.6	-3.3	-2.9	-2.4	-1.7	-3.0
Sitting height	1.4	10.0	18.9	-4.0	-3.7	-3.4	-2.4	-4.1	-3.6	-3.4	-3.0	-3.3	-1.5	-1.5	-2.0	-3.7	-3.8	-3.1	-3.3	-2.8	0.1	-4.4	-2.8	-4.3	-3.6	-1.5	-3.1	-2.8
Leg fat percentage (left)	1.4	5.0	7.5	2.1	2.0	1.9	2.1	2.1	2.1	2.0	2.6	2.2	1.4	1.9	2.2	2.6	2.3	2.6	2.2	2.2	2.4	2.3	2.4	2.6	2.7	2.0	1.7	2.3
Bipolar Disorder or Schizophrenia	1.3	3.1	6.1	-1.7	-2.3	-1.1	-0.9	-2.1	-2.1	-2.5	-2.3	-2.2	-0.7	-1.5	-1.4	-2.0	-0.8	-2.2	-2.2	-1.8	-1.0	-1.4	-1.9	-1.7	-1.8	-1.6	-1.7	-1.9
Age at First Birth	1.3	1.8	3.9	-1.5	-0.2	-2.0	-1.6	-0.7	-0.3	-0.9	-1.5	-1.5	-1.7	-1.5	-1.5	-1.3	-2.0	-1.5	-0.7	-1.8	-0.4	-1.6	-1.5	-1.4	-0.9	-1.5	0.1	-1.5
Coronary Artery Disease (CAD)	1.3	1.5	4.1	0.9	0.9	0.9	1.1	1.9	1.4	0.7	1.4	1.0	0.7	1.0	0.8	1.8	1.3	0.9	0.9	0.7	-0.5	1.4	1.7	1.9	2.0	0.0	1.1	1.1
Trunk fat percentage	1.3	5.1	9.5	1.9	1.3	2.1	2.6	1.4	1.2	1.5	3.1	2.7	2.7	3.1	2.6	2.1	2.3	2.7	1.5	2.7	2.1	1.6	3.0	2.0	2.0	2.9	0.6	2.7
Mouth/teeth dental problems: Dentures	1.3	2.2	4.9	1.5	1.1	1.8	1.5	0.8	1.4	1.0	2.1	1.6	2.2	2.1	1.3	0.6	1.0	1.7	0.9	2.2	-0.9	1.6	1.6	0.7	0.9	2.2	0.4	1.6
Blood clot in the leg (DVT)	1.3	1.7	6.7	-1.5	-1.7	-1.1	-0.6	-1.6	-1.6	-1.4	-0.9	-1.0	-0.2	0.0	-0.9	-1.1	-1.3	-1.1	-1.5	-0.6	-2.6	-1.4	-0.8	-1.9	-1.7	0.1	-1.8	-0.9
Long-standing illness, disability or infirmity	1.3	1.9	4.0	1.6	1.5	1.2	0.6	2.0	1.9	1.8	1.2	1.3	1.0	0.5	0.6	1.7	1.4	1.4	1.7	1.2	1.6	1.9	0.9	1.4	1.6	0.6	1.5	0.8
Back pain experienced in last month	1.3	1.9	4.3	1.2	1.8	0.8	1.2	2.1	1.6	1.6	1.5	1.4	1.0	0.9	0.6	1.7	0.8	1.3	1.8	1.2	1.6	1.0	1.4	1.2	1.9	1.1	1.3	1.1
Number of operations (self-reported)	1.3	1.9	6.0	-2.3	-1.5	-1.8	-0.8	-1.6	-1.7	-1.7	-1.3	-1.5	0.6	-0.6	-0.8	-0.5	-1.4	-1.3	-1.4	-1.5	-0.2	-2.4	-0.8	-1.8	-1.3	-0.3	-1.4	-1.1
Supplements: Calcium	1.3	1.4	3.3	-1.6	-1.6	-1.6	-1.2	-0.8	-1.0	-1.1	-1.7	-1.2	-0.5	-1.7	-1.2	-0.3	-1.0	-1.6	-0.8	-1.8	-0.5	-1.1	-1.1	-0.8	-0.4	-1.5	-0.3	-1.3
Respiratory disease	1.2	2.7	4.3	-2.0	-1.8	-2.0	-1.8	-1.9	-1.6	-1.6	-2.0	-1.4	-1.5	-1.7	-1.5	-1.6	-1.4	-1.9	-1.6	-2.1	-0.1	-1.2	-1.8	-1.5	-1.3	-1.9	-0.9	-1.8
Frequency of depressed mood in last 2 weeks	1.2	1.6	6.2	-0.7	0.7	-1.3	-2.1	0.1	0.4	0.5	-0.5	-0.7	-1.4	-1.0	-2.5	-1.6	-2.5	-1.2	0.8	-0.8	0.6	-1.2	-1.5	-1.9	-0.9	-0.9	0.7	-1.8
Diabetes (father)	1.2	1.5	3.2	-1.7	-1.2	-1.8	-1.2	-0.7	-1.3	-1.3	-1.6	-1.3	-1.3	-1.2	-0.9	-0.5	-0.9	-1.4	-1.1	-1.6	-1.2	-1.7	-0.9	-0.9	-0.8	-0.8	-1.0	-1.0
Medication: Levothyroxine sodium	1.2	2.1	5.3	0.9	0.5	1.1	1.9	1.3	0.9	0.7	1.5	1.7	2.3	1.7	1.6	2.0	1.7	1.6	0.7	1.7	1.7	0.7	1.9	1.1	1.1	1.9	0.1	1.4
Time employed in main current job	1.2	1.4	3.3	1.6	1.8	1.2	0.4	1.6	1.4	1.6	1.3	1.5	0.7	0.5	0.1	0.7	1.3	0.9	1.5	1.1	0.2	1.1	1.1	1.4	1.0	0.9	1.4	0.9
Body fat percentage	1.2	4.9	8.4	1.9	1.6	2.0	2.4	1.6	1.5	1.6	2.9	2.6	2.4	2.7	2.4	2.3	2.3	2.7	1.7	2.5	2.1	1.8	2.8	2.2	2.2	2.4	0.9	2.5
Leg fat percentage (right)	1.2	4.2	7.5	1.9	2.0	1.6	1.7	2.2	2.2	2.0	2.2	1.9	1.2	1.4	1.8	2.6	2.0	2.3	2.2	1.8	2.2	2.3	2.1	2.5	2.7	1.5	1.9	1.9
Age at first live birth	1.2	2.1	7.4	-1.5	-2.4	-0.6	0.1	-2.2	-2.7	-2.2	-1.0	-1.2	0.0	0.3	0.4	-1.2	-0.6	-1.1	-2.4	-0.9	0.4	-1.7	-0.4	-1.2	-1.8	-0.2	-2.4	-0.4
Deep venous thrombosis (DVT) (self-reported)	1.2	1.5	7.5	-1.4	-1.7	-0.9	-0.4	-1.6	-1.5	-1.4	-0.8	-1.0	0.0	0.1	-0.6	-0.8	-1.2	-0.9	-1.5	-0.4	-2.7	-1.1	-0.5	-1.7	-1.4	0.4	-1.8	-0.7
Fasting Glucose	1.1	1.3	4.2	0.9	0.5	1.2	1.4	0.5	0.4	0.5	1.5	2.1	-1.4	1.8	1.5	1.2	1.2	1.3	0.3	1.5	-0.3	1.1	1.1	0.9	0.2	1.4	-0.3	1.1
Hypothyroidism (self reported)	1.1	2.5	9.0	0.8	0.3	1.0	1.8	1.0	0.5	0.5	1.8	1.7	2.5	2.3	1.2	1.6	1.5	1.4	0.6	2.0	3.0	-0.0	2.2	0.9	0.8	2.5	-0.5	1.8
Allergy	1.1	2.5	6.7	1.2	1.2	1.2	1.7	1.1	0.8	1.1	2.2	1.7	2.6	2.1	2.1	1.5	1.1	2.0	1.0	1.8	1.0	1.3	2.0	1.5	1.7	2.0	0.5	1.5
Ever highly irritable/argumentative for 2 days	1.1	1.3	2.9	1.2	1.6	1.0	0.3	1.4	1.3	1.5	1.6	1.5	0.6	1.1	0.3	0.5	0.3	1.2	1.6	1.4	1.4	0.7	0.7	0.5	0.7	1.7	1.0	0.7
Qualifications: O levels/GCSEs or equivalent	1.1	1.7	6.3	1.7	0.4	1.8	1.7	1.0	0.3	0.8	0.8	0.9	0.9	0.4	1.4	1.5	2.0	1.0	1.0	0.7	0.7	2.0	1.4	2.5	1.7	0.0	0.8	1.5
Shortness of breath walking on level ground	1.1	1.3	4.4	0.4	0.6	0.7	1.5	0.8	0.7	0.6	1.7	1.4	1.0	1.9	1.2	0.9	-0.0	1.4	0.7	1.5	0.4	0.4	1.7	0.4	0.8	2.1	0.0	1.5
Irritable Bowel Disease (IBD)	1.0	2.3	5.4	1.1	0.6	1.2	2.2	1.1	0.5	0.9	1.3	1.6	1.2	1.3	2.3	2.1	1.2	1.8	0.7	1.5	1.7	1.2	2.1	1.5	1.8	1.8	0.1	2.3
LDL Cholesterol	1.0	1.5	6.8	1.4	1.8	0.7	0.0	1.7	1.9	1.7	1.1	0.9	0.2	0.0	0.3	0.4	1.0	0.9	1.5	0.6	2.6	0.4	0.7	1.2	1.3	-0.5	2.1	0.9
Lupus	1.0	1.5	3.2	-1.2	-1.1	-1.1	-1.2	-1.3	-1.4	-1.1	-1.1	-1.5	-1.6	-0.6	-0.9	-1.2	-1.1	-1.4	-1.1	-1.2	-0.2	-1.4	-1.6	-1.5	-1.8	-0.8	-1.1	-1.4
Hearing difficulty/problems: Yes	1.0	1.5	3.3	-1.3	-0.1	-1.7	-1.6	-0.3	0.1	-0.4	-1.3	-1.6	-1.7	-1.5	-1.3	-1.1	-1.8	-1.1	-0.4	-1.4	1.3	-1.0	-1.8	-1.3	-0.7	-1.4	0.3	-1.5
Medication: Metformin	1.0	1.3	2.6	-1.4	-0.8	-1.1	-1.0	-1.2	-1.2	-1.5	-1.6	-1.3	-0.3	-1.1	-0.9	-1.2	-0.1	-1.4	-1.4	-1.4	0.1	-0.9	-1.3	-1.0	-1.4	-0.9	-1.1	-1.5
Hand grip strength (right)	1.0	2.7	6.6	-1.2	-0.2	-1.9	-2.5	-0.8	-0.4	-0.2	-1.8	-1.8	-2.6	-2.4	-2.1	-1.8	-1.8	-1.9	0.3	-2.1	1.2	-1.2	-2.1	-1.1	-1.1	-1.9	0.7	-2.0
Number of incorrect matches in round	1.0	1.6	3.6	-1.8	-1.4	-1.6	-1.5	-1.2	-1.2	-1.4	-1.1	-0.9	-0.3	-0.4	-1.0	-1.3	-1.0	-1.2	-1.6	-1.0	-0.0	-1.5	-1.3	-1.9	-1.6	-0.3	-1.3	-1.7
Loud music exposure frequency	1.0	1.1	3.5	1.1	1.5	0.8	0.9	1.1	1.1	1.4	1.1	1.0	0.9	0.5	0.9	1.1	0.1	1.2	1.5	0.9	1.9	0.9	0.8	0.8	0.8	0.9	1.0	1.1
Medication: Allopurinol	1.0	1.3	4.3	0.5	0.2	1.0	1.5	0.0	-0.1	0.1	1.5	1.0	2.1	2.1	1.6	0.6	1.0	1.4	0.0	1.5	0.7	-0.0	1.5	0.5	0.4	1.7	-0.6	1.5
Qualifications: NVQ or HND or HNC or equivalent	1.0	1.2	4.8	-0.1	0.6	-0.8	-1.4	0.8	0.9	0.6	-1.2	-0.8	-1.9	-2.2	-1.1	-0.4	-0.4	-0.7	1.2	-1.2	0.6	0.4	-1.3	0.1	0.2	-2.2	1.4	-0.8
Hearing aid user	1.0	1.1	2.6	1.1	1.0	1.0	0.7	1.5	1.2	1.1	1.3	1.3	1.2	1.1	0.7	0.8	1.1	1.2	0.9	1.2	1.6	0.8	1.0	1.0	0.7	0.3	0.7	0.7
Financial situation satisfaction	1.0	1.2	5.2	-0.2	1.9	-1.2	-1.1	1.1	1.7	1.5	-0.0	-0.3	-0.8	-1.2	-1.1	0.2	-2.3	0.0	1.6	-0.5	-0.8	-0.0	-0.6	-0.4	0.4	-0.5	1.9	-1.0
Heart attack/myocardial infarction (self-reported)	1.0	1.3	6.1	0.5	2.1	-0.6	-0.2	2.5	2.1	1.8	0.7	1.0	-0.2	-0.2	-0.6	1.3	-0.6	0.7	2.0	0.4	-0.4	0.2	0.8	0.5	1.1	-0.0	1.8	0.5
Major Depression (MDD)	0.9	1.1	3.6	-0.1	-0.9	-0.0	-1.1	-1.2	-1.0	-0.8	-1.3	-0.8	-0.1	-1.1	-1.2	-1.9	0.1	-1.2	-0.9	-0.7	1.5	-0.6	-1.6	-1.2	-1.7	-0.5	-0.7	-1.1
Schizophrenia (2014)	0.9	2.1	3.8	-1.6	-1.5	-1.3	-1.2	-1.3	-1.4	-1.6	-1.9	-1.7	-0.6	-1.6	-1.3	-1.4	-0.7	-1.9	-1.4	-1.8	-0.7	-1.0	-1.6	-1.2	-1.4	-2.0	-0.8	-1.9
Heart attack	0.9	1.1	5.2	0.3	2.0	-0.7	-0.4	2.3	1.9	1.6	0.6	0.8	-0.3	-0.3	-0.7	1.0	-0.8	0.5	1.7	0.3	-0.4	-0.0	0.5	0.2	0.9	-0.1	1.7	0.3
Pain all over the body in last month	0.9	0.9	4.6	-0.3	0.8	-1.1	-0.6	0.6	0.8	0.9	-0.2	-0.6	-2.2	-1.1	-0.4	1.2	-1.1	-0.1	1.1	-0.9	-0.6	0.1	-0.2	0.9	1.4	-1.5	1.6	-0.3
Noisy workplace	0.9	1.1	1.9	1.3	1.2	1.4	1.2	1.1	1.2	1.2	1.1	1.0	0.6	0.7	0.9	1.3	0.2	1.4	1.2	1.3	-0.1	0.9	0.8	0.6	0.8	1.4	0.9	1.0
Age at last live birth	0.9	1.3	3.0	-1.3	-1.5	-0.7	-0.2	-1.6	-1.5	-1.4	-0.8	-1.2	0.1	-0.1	0.0	-1.4	-1.4	-0.8	-1.4	-0.8	1.1	-1.7	-0.7	-1.4	-1.4	-0.3	-1.3	-0.5
Illnesses of father: High blood pressure	0.9	1.1	3.6	0.8	1.9	0.3	0.3	1.6	1.5	1.5	0.9	0.9	-0.3	-0.1	0.1	1.2	0.1	0.7	1.6	0.3	-0.1	0.8	0.8	1.1	1.6	-0.4	1.9	0.7
Alzheimer’s Disease (including proxy)	0.8	1.1	3.5	1.1	0.9	1.3	0.9	0.8	0.9	0.6	1.5	1.4	0.7	1.7	1.4	0.3	1.9	1.3	0.1	1.6	0.7	0.3	1.1	0.5	0.2	1.4	0.1	1.0
Medication for hormone replacement therapy	0.8	0.9	2.2	-1.5	-1.3	-1.4	-0.6	-1.2	-1.4	-1.3	-0.8	-0.6	0.2	-0.1	0.1	-0.7	-0.8	-0.6	-1.3	-0.8	-0.3	-1.5	-0.4	-1.1	-0.9	-0.2	-1.3	-0.6
Stomach or abdominal pain in last month	0.8	1.0	2.5	-0.5	0.3	-0.8	-1.5	0.0	0.1	-0.1	-0.9	-1.3	-0.7	-1.2	-1.6	-1.4	-1.6	-1.1	0.2	-0.9	0.2	-1.1	-1.4	-1.2	-0.9	-0.8	0.4	-1.5
Impedance of arm (left)	0.8	3.6	7.6	1.9	-0.1	2.7	2.6	0.7	0.0	0.3	2.0	2.2	2.8	2.7	2.2	1.7	2.5	1.8	-0.1	2.5	-0.1	1.1	2.4	1.6	0.9	2.5	-0.7	2.6
Gout (self-reported)	0.8	1.2	3.4	0.8	0.7	0.9	1.4	0.6	0.5	0.7	1.1	0.7	0.7	1.0	1.8	1.3	1.0	1.5	0.7	1.0	1.8	0.8	1.2	1.3	1.1	0.6	0.4	1.6
High blood pressure (siblings)	0.8	1.2	3.6	0.8	1.5	0.2	0.7	1.9	1.7	1.2	1.1	1.0	0.4	0.6	0.8	1.3	0.9	1.3	1.0	0.8	0.6	1.6	1.2	1.4	1.0	0.2	1.2	0.8
Family relationship satisfaction	0.8	0.9	3.6	-0.0	1.2	-0.8	-1.1	1.3	1.4	1.3	0.1	0.1	-0.4	-0.9	-1.3	0.1	-1.5	-0.2	1.3	-0.3	-1.9	0.1	-0.3	-0.1	0.7	-0.6	1.6	-0.9
Leg pain on walking	0.8	1.0	3.4	-0.5	1.1	-1.2	-1.4	0.7	0.9	1.0	-0.2	0.0	-0.3	-1.0	-1.0	-0.7	-1.9	-0.2	1.1	-0.7	1.8	-0.7	-0.8	-1.2	0.1	-0.8	1.2	-0.9
Loneliness, isolation	0.8	1.0	3.7	-0.9	-0.6	-0.6	-0.7	-0.7	-0.9	-0.8	-0.8	-1.2	-0.2	-0.5	-1.3	-1.4	-1.7	-1.1	-0.5	-0.5	0.4	-1.5	-1.2	-1.9	-1.4	-0.4	-0.8	-1.2
Medication for cholesterol	0.8	1.2	3.7	-1.0	-1.6	-0.2	-0.0	-1.9	-1.7	-1.4	-0.5	-0.9	0.7	0.5	-0.0	-1.6	-1.2	-0.6	-1.4	-0.2	-0.7	-0.8	-0.6	-1.7	-1.1	0.4	-1.7	-0.4
Asthma (self-reported)	0.8	1.6	2.8	-1.5	-1.2	-1.6	-1.2	-1.2	-0.9	-1.0	-1.7	-1.3	-1.5	-1.6	-1.1	-0.7	-1.3	-1.4	-0.8	-1.6	1.0	-0.8	-1.4	-1.1	-1.2	-1.7	-0.5	-1.1
Ever had prostate specific antigen (PSA) test	0.8	1.0	2.3	1.0	1.2	0.7	0.5	1.2	1.3	1.1	1.0	1.2	0.4	0.3	0.5	1.0	0.6	0.9	1.4	0.6	0.8	1.3	0.8	1.2	1.5	0.0	1.4	0.6
Depressed Affect (Nagel 2018)	0.7	1.5	6.2	-0.8	-1.0	-0.0	-0.5	-1.2	-1.0	-1.4	-0.6	-0.5	0.3	0.3	-1.1	-2.3	-1.4	-0.9	-1.4	0.0	-0.0	-1.4	-1.3	-2.5	-2.4	0.4	-1.6	-1.4
Schizophrenia vs Biploar Disorder	0.7	0.9	2.9	0.8	1.1	0.4	0.7	1.3	1.0	1.2	0.6	0.5	0.6	-0.1	0.4	1.3	0.5	0.7	1.2	0.1	0.8	1.1	0.8	1.4	1.7	-0.2	1.4	0.8
Bipolar Disorder (2011)	0.7	0.7	2.5	-0.8	-1.6	-0.3	0.1	-1.0	-1.3	-1.4	-0.7	-0.5	0.1	0.2	-0.3	-0.6	-0.3	-0.9	-1.5	-0.4	-0.7	-0.7	-0.3	-0.8	-1.0	-0.3	-1.4	-0.3
Crohns Disease (2012)	0.7	1.1	2.5	-1.3	-0.3	-1.6	-1.5	-1.0	-0.7	-0.6	-1.2	-0.9	-0.9	-1.2	-1.2	-0.9	-1.6	-1.2	-0.6	-1.4	-0.2	-0.7	-1.1	-1.1	-0.8	-1.2	-0.3	-1.0
Primary Biliary Cirrhosis	0.7	0.9	2.9	-0.7	-1.0	-0.1	-0.4	-1.1	-1.1	-1.2	-0.8	-0.7	0.6	-0.1	-1.1	-1.3	-0.4	-1.1	-1.3	-0.3	-1.1	-1.4	-0.6	-1.5	-1.7	-0.2	-1.2	-0.6
Taking other prescription medications	0.7	1.0	2.1	0.8	0.4	1.1	1.4	0.9	0.8	0.4	1.1	0.7	1.5	1.2	1.2	1.1	0.8	1.2	0.4	1.3	1.4	0.8	1.2	0.9	0.8	1.3	0.1	1.2
Heel bone mineral density (BMD) T-score, automated (left)	0.7	1.7	8.6	1.3	0.9	1.4	1.0	1.3	1.4	1.1	1.4	1.3	1.6	1.0	1.4	0.7	0.9	1.5	1.0	1.3	2.9	1.4	1.0	0.9	0.7	0.4	1.0	1.4
Tinnitus: Yes, but not now, but have in the past	0.7	0.7	1.4	1.1	1.0	1.1	0.8	0.6	0.6	0.8	1.0	0.9	0.5	0.9	0.6	0.9	1.1	0.8	0.8	1.1	0.5	1.2	0.7	0.7	0.4	1.0	0.2	0.8
Body mass index (BMI)	0.7	3.1	6.5	1.5	2.1	1.1	1.4	1.9	2.0	2.0	2.0	1.8	1.0	1.2	1.4	1.9	1.4	2.0	2.3	1.4	2.5	1.7	1.9	2.0	2.2	1.0	1.9	1.5
Had menopause	0.7	0.9	3.3	-0.1	-1.1	0.5	0.8	-0.8	-0.9	-1.3	0.4	0.1	1.0	1.5	0.5	0.0	1.6	-0.0	-1.3	0.7	-1.5	-0.0	0.8	0.3	0.3	1.8	-1.7	0.3
Medication: Simvastatin	0.7	1.0	1.8	0.9	1.2	0.8	1.0	1.4	1.3	1.1	1.1	1.1	0.9	0.7	0.8	1.1	1.0	1.1	1.1	1.0	0.9	0.5	1.4	1.1	1.1	0.7	0.9	1.1
Impedance of arm (right)	0.7	3.1	7.0	1.7	-0.3	2.5	2.6	0.4	-0.2	0.2	1.8	2.0	2.6	2.5	2.2	1.4	2.2	1.7	-0.3	2.2	-0.1	1.2	2.2	1.3	0.7	2.3	-0.8	2.5
Pulse wave peak to peak time	0.7	0.8	2.4	-0.6	0.0	-1.0	-1.6	-0.5	-0.5	-0.1	-1.0	-0.7	-0.9	-1.4	-1.4	-1.1	-0.9	-1.2	0.1	-1.2	-0.4	-0.6	-1.4	-0.5	-0.2	-1.1	0.2	-1.1
Angina (self-reported)	0.7	0.9	2.2	0.6	1.2	0.3	0.9	1.5	1.1	0.9	1.0	0.8	1.0	0.8	1.0	1.3	0.8	1.1	0.8	0.8	0.7	0.6	1.2	1.0	1.5	0.9	0.7	1.0
Medication: Ibuprofen	0.7	0.9	3.0	1.4	1.1	1.1	0.0	1.1	1.5	1.4	0.6	0.4	-0.9	-0.4	-0.2	0.4	0.3	0.5	1.4	0.5	1.5	1.2	0.1	1.0	0.8	-0.3	1.7	0.4
Commuting to job workplace: Walk	0.7	0.7	3.3	-0.4	-1.2	0.4	0.6	-1.6	-1.8	-1.4	-0.5	-0.4	0.5	0.3	0.4	-0.5	0.3	-0.6	-1.5	-0.2	-0.0	-0.5	-0.0	-0.5	-0.8	-0.4	-1.6	0.4
Commuting to job workplace: Public transport	0.7	0.8	2.4	-0.8	-0.7	-1.0	-1.1	-0.8	-0.4	-0.6	-1.0	-0.7	-0.7	-1.0	-1.1	-1.0	-0.5	-1.0	-0.6	-1.1	-1.6	-0.8	-0.8	-0.8	-0.5	-1.2	-0.1	-1.2
Fractured/broken bones in last 5 years	0.7	0.9	2.8	-0.8	0.0	-1.0	-1.3	-0.5	-0.3	-0.3	-0.9	-0.7	-1.1	-1.1	-1.4	-1.1	-1.3	-1.1	-0.1	-1.0	0.0	-1.7	-1.1	-1.2	-0.7	-1.1	0.1	-0.9
Myopia	0.7	1.0	3.3	1.2	1.0	1.0	0.7	0.6	0.8	1.0	1.3	1.8	1.1	1.1	0.6	0.6	1.3	1.0	0.9	1.1	0.6	0.6	1.3	1.1	0.6	0.5	0.6	1.1
Cholesterol lowering medication	0.7	1.0	3.3	0.7	1.5	0.0	0.3	1.8	1.5	1.3	0.3	0.3	-0.7	-0.6	-0.0	1.7	0.4	0.5	1.4	0.0	0.1	0.6	0.6	1.5	1.7	-0.8	1.8	0.3
Schizophrenia (2018)	0.6	1.3	3.1	-1.1	-1.0	-0.9	-0.7	-1.0	-1.2	-1.3	-1.8	-1.5	-0.6	-1.7	-1.2	-0.9	-0.5	-1.6	-1.0	-1.6	-0.6	-0.6	-1.3	-0.6	-0.7	-1.5	-0.5	-1.6
Alzheimer’s Disease (in mother)	0.6	0.7	2.5	0.8	0.6	0.9	0.3	0.8	0.9	0.5	1.4	1.2	0.5	1.6	0.7	0.1	1.1	1.1	0.3	1.4	0.0	0.4	0.8	0.4	0.2	1.1	0.2	0.5
HbA1C	0.6	0.7	2.7	-0.7	0.9	-1.1	-0.6	0.8	0.8	0.8	0.0	0.2	1.6	-0.4	-0.8	0.4	-1.6	0.1	0.9	0.1	1.6	-1.1	0.3	-1.0	0.1	0.6	0.5	0.1
Waist Hip Ratio (WHR)	0.6	2.9	11.7	-0.9	-2.7	0.6	1.8	-1.6	-2.7	-2.4	0.2	0.1	2.0	2.2	1.5	-0.4	1.1	0.1	-2.4	0.8	2.1	-1.1	0.9	-0.4	-0.8	2.4	-3.4	0.9
Cardiovascular Disease	0.6	1.9	4.8	1.6	2.1	0.9	0.5	2.1	2.0	1.8	0.8	0.9	-0.7	-0.3	-0.1	1.6	1.2	0.9	2.0	0.5	1.1	1.8	0.8	2.0	1.7	-0.8	2.2	0.6
Number of treatments/medications taken	0.6	1.0	5.7	1.1	1.3	0.8	0.3	1.3	1.4	1.2	0.9	0.8	0.1	0.3	0.2	1.0	0.9	0.8	1.3	0.8	2.4	1.1	0.5	1.1	0.9	0.3	1.2	0.6
Bilateral oophorectomy (both ovaries removed)	0.6	0.7	2.6	-0.3	-0.9	0.5	1.3	-0.7	-0.9	-1.2	-0.1	-0.1	1.0	0.9	0.8	0.1	0.7	0.2	-1.1	0.6	-1.1	-0.9	0.5	-0.4	-0.5	1.4	-1.6	0.8
Medication: Atenolol	0.6	0.8	2.3	-0.4	-0.5	-0.4	-0.9	-0.5	-0.3	-0.7	-1.1	-1.5	-0.9	-1.1	-1.4	-1.0	-0.4	-1.2	-0.8	-0.9	-0.9	-0.4	-1.3	-0.3	-0.8	-0.8	-0.0	-1.2
Frequency of tenseness / restlessness in last 2 weeks	0.6	1.0	3.0	-0.9	-0.7	-0.5	-0.8	-0.8	-1.0	-0.8	-0.7	-0.9	-1.0	-0.2	-1.3	-1.1	-1.3	-1.1	-1.0	-0.5	-1.0	-1.0	-1.1	-1.7	-1.3	0.0	-1.0	-1.1
Hair/balding pattern: Pattern 2	0.6	0.7	1.7	0.8	0.9	0.9	0.8	0.8	0.8	0.6	1.0	0.5	-0.9	0.8	1.0	0.8	0.4	1.0	0.7	0.8	-1.1	0.7	0.8	1.0	1.2	0.7	0.6	1.3
Serious illness, injury or assault of a close relative in last 2 years	0.6	0.7	2.9	0.7	0.7	0.3	1.0	0.8	0.4	0.7	0.7	0.1	0.0	0.2	1.0	1.6	0.5	0.7	1.1	0.2	0.8	0.6	0.9	1.7	1.3	0.1	1.0	1.0
Exposure to tobacco smoke at home	0.6	0.6	5.0	0.1	-0.2	0.7	0.8	0.1	0.0	-0.3	0.7	0.2	0.1	1.5	0.9	-0.2	-0.2	0.8	-0.2	1.2	-1.2	-0.0	0.0	-0.9	-0.1	2.2	-1.1	0.3
Hair/balding pattern: Pattern 4	0.6	1.4	4.8	1.1	1.7	0.7	0.2	2.2	2.1	1.6	1.0	1.2	-0.2	0.2	-0.0	1.6	1.0	0.9	1.6	0.8	1.0	1.2	0.8	1.3	0.9	0.3	1.8	0.3
Chronic bronchitis/emphysema (mother)	0.6	0.7	2.7	-1.4	-0.0	-1.5	-1.0	-0.2	-0.0	-0.3	-0.7	-0.7	-0.3	-0.9	-0.6	-0.4	-1.4	-0.6	-0.1	-1.1	-1.6	-0.9	-0.7	-1.0	-0.0	-0.6	0.2	-0.6
Health satisfaction	0.6	0.8	4.2	0.3	1.3	-0.3	-0.6	1.2	1.3	1.5	0.7	0.4	-0.6	-0.1	-0.3	0.2	-2.0	0.6	1.7	0.3	0.5	-0.5	-0.2	-0.6	0.6	0.3	1.4	-0.1
Mouth/teeth dental problems: Loose teeth	0.6	0.7	3.2	0.8	1.6	0.2	-0.9	1.0	1.5	1.5	0.6	0.4	-0.8	-0.3	-0.7	-0.0	-0.2	0.3	1.4	0.2	0.7	0.9	-0.2	0.3	0.2	-0.6	1.8	-0.3
Medication for pain relief, constipation, heartburn	0.6	1.0	3.7	-0.4	-1.8	0.2	0.7	-1.3	-1.8	-1.5	-0.4	-0.4	1.1	0.7	0.8	-0.1	1.0	-0.2	-1.7	-0.0	-1.4	-0.8	0.4	0.0	-0.7	0.3	-1.9	0.4
Illness, injury, bereavement, stress in last 2 years	0.6	0.7	4.4	1.0	0.6	1.2	0.6	0.4	0.5	0.1	0.3	1.2	-0.2	0.5	1.0	0.4	2.1	0.8	-0.1	0.9	-0.7	1.4	0.4	0.9	0.3	0.9	-0.3	0.8
Average weekly red wine intake	0.6	0.9	3.6	-0.5	-1.9	0.3	0.9	-1.2	-1.5	-1.5	-0.3	-0.1	0.2	0.8	1.0	-0.0	1.0	-0.2	-1.7	0.1	-0.9	-0.3	0.3	-0.3	-0.8	0.5	-1.8	0.2
Mouth/teeth dental problems: Mouth ulcers	0.6	0.9	2.8	0.9	-0.1	1.5	1.7	0.5	-0.0	-0.2	0.7	0.9	1.3	1.1	1.3	0.8	1.7	0.8	-0.4	1.1	0.1	0.7	1.1	0.8	0.7	1.0	-0.5	1.2
Medication: Aspirin	0.6	0.8	2.5	0.4	1.4	0.1	0.8	1.2	0.8	1.0	0.7	1.1	0.9	0.2	0.6	1.6	0.5	0.8	1.0	0.5	1.2	0.6	1.1	0.9	1.3	0.2	0.8	0.8
Eye problems/disorders: Glaucoma	0.6	0.7	3.8	0.8	1.1	0.5	0.4	1.1	1.3	1.1	0.7	1.0	0.3	0.2	0.6	0.8	0.2	0.9	1.2	0.7	2.0	0.5	0.4	0.6	0.7	-0.0	1.0	0.7
Pain type(s) experienced in last month: Hip pain	0.6	0.8	3.5	0.5	1.4	0.0	0.2	1.9	1.8	1.4	0.9	0.6	-0.3	0.3	-0.0	0.4	-0.9	0.9	1.5	0.7	0.3	0.5	0.3	0.0	0.9	-0.0	1.4	0.2
High cholesterol (Self-reported)	0.6	1.0	4.2	0.6	1.8	-0.2	-0.6	1.9	1.8	1.3	0.0	0.0	-0.8	-1.1	-0.6	0.7	0.2	0.2	1.6	-0.3	0.1	0.5	-0.1	0.9	1.3	-0.6	2.1	-0.3
Impedance of whole body	0.6	3.0	6.9	1.9	0.1	2.6	2.2	0.6	0.1	0.3	1.9	2.0	2.5	2.5	1.9	1.2	2.2	1.7	0.0	2.4	-0.5	1.0	2.0	1.3	0.7	2.5	-0.6	2.5
Ovarian Cancer	0.5	0.7	1.8	1.1	1.0	0.8	0.2	0.8	1.2	1.1	1.2	0.6	-0.2	0.7	0.1	0.5	0.1	0.8	1.3	1.0	1.0	0.7	0.6	0.9	0.8	0.7	1.1	0.5
Body Mass Index (BMI) (2010)	0.5	0.6	2.8	0.5	1.3	0.1	-0.4	0.8	1.0	1.0	0.2	-0.0	-1.7	-0.7	-0.4	0.3	-0.1	0.1	0.9	-0.2	1.1	1.2	-0.3	0.9	0.8	-1.0	1.4	-0.1
Relative age of first facial hair	0.5	1.0	1.9	-0.9	-0.5	-1.1	-1.3	-0.9	-0.6	-0.9	-1.4	-1.0	-0.9	-1.2	-1.0	-1.2	-0.1	-1.1	-1.1	-1.2	-0.5	-0.9	-1.3	-1.0	-1.1	-1.0	-0.5	-1.2
Severe depression (siblings)	0.5	0.5	1.7	1.2	1.0	1.3	0.5	0.5	0.3	0.6	0.6	1.3	1.0	0.5	0.2	0.1	1.3	0.5	0.5	1.0	0.6	0.7	0.4	0.4	0.0	0.5	0.1	0.7
Townsend deprivation index at recruitment	0.5	0.7	3.0	-0.1	-0.3	0.5	0.8	-0.9	-0.7	-0.8	0.3	0.1	1.7	1.2	1.0	-0.6	0.2	0.5	-0.8	0.8	0.9	-0.3	0.2	-0.9	-0.8	1.6	-1.4	0.8
Fed-up feelings	0.5	0.8	4.5	-0.7	-0.4	-0.3	-0.3	-0.7	-0.5	-0.6	-0.1	-0.6	0.0	0.4	-0.7	-1.5	-1.9	-0.4	-0.4	0.2	0.4	-1.2	-0.7	-2.1	-1.4	0.8	-1.0	-1.0
Serious illness, injury or assault to yourself	0.5	0.6	4.0	-0.2	-0.7	0.5	1.3	-0.4	-0.6	-0.5	0.6	0.3	2.0	1.2	0.7	0.8	0.4	0.3	-0.3	0.6	0.5	-0.1	1.2	0.2	0.3	0.4	-0.8	0.9
Nervous feelings	0.5	0.9	2.9	1.4	1.3	1.4	0.7	1.7	1.5	1.2	0.8	0.6	0.7	0.3	0.0	0.4	0.2	0.7	0.9	1.0	1.3	1.5	0.4	0.3	0.6	0.5	1.2	0.5
Had other major operations	0.5	0.6	1.5	-1.2	-1.1	-0.6	0.2	-1.0	-1.0	-1.2	-0.7	-0.9	0.3	-0.1	-0.4	-0.8	-0.3	-0.8	-1.2	-0.6	-0.2	-1.1	-0.3	-1.1	-0.8	0.2	-1.1	-0.5
Medication: Ramipril	0.5	0.6	3.3	-0.6	0.3	-0.9	-1.3	-0.3	-0.2	-0.1	-0.7	-0.5	-1.8	-0.9	-0.6	-0.7	-0.5	-0.6	0.2	-0.9	1.4	-0.6	-1.0	-0.5	-0.5	-0.6	0.2	-0.7
Number of live births	0.5	0.7	2.9	0.7	0.6	0.8	1.1	0.4	0.4	0.5	0.7	0.7	1.7	0.6	1.3	0.7	1.1	1.0	0.7	0.7	0.5	1.0	0.9	0.9	1.2	0.5	0.4	1.0
Asthma	0.5	1.0	1.9	-1.2	-1.0	-1.3	-0.9	-1.0	-0.7	-0.8	-1.4	-1.0	-1.3	-1.3	-0.8	-0.5	-1.0	-1.1	-0.6	-1.3	1.0	-0.5	-1.1	-0.9	-1.2	-1.3	-0.5	-0.9
Arm fat mass (right)	0.5	1.9	4.4	0.9	1.2	0.9	1.6	1.0	1.0	1.1	1.8	1.5	1.4	1.6	1.6	1.5	1.2	1.7	1.2	1.3	2.1	1.1	1.9	1.4	1.6	1.4	0.8	1.5
Medication: Paracetamol	0.5	0.8	3.3	0.7	1.8	0.2	-0.7	1.2	1.8	1.4	0.7	0.9	-0.3	0.0	-0.7	-0.8	-0.4	0.4	1.6	0.6	1.1	0.6	-0.3	-0.5	0.2	0.4	1.4	-0.3
Neck or shoulder pain in last month	0.5	0.6	2.9	0.9	1.4	0.8	0.6	1.7	1.3	0.9	0.5	0.7	0.4	0.1	0.0	0.4	0.3	0.6	1.1	0.8	0.6	0.7	0.4	0.5	0.7	0.7	0.9	0.7
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.5	0.6	1.6	0.7	0.8	0.5	0.6	0.9	0.8	0.9	0.8	0.8	1.3	0.4	0.5	0.7	0.6	0.8	1.1	0.6	1.2	0.7	0.7	0.9	1.1	0.4	0.7	0.4
Chest pain or discomfort	0.5	0.8	2.5	0.5	0.2	0.7	1.2	0.8	0.5	0.4	1.3	0.6	1.5	1.6	0.9	0.6	0.1	1.1	0.7	1.3	-0.1	-0.1	1.1	0.0	0.6	1.6	-0.1	0.9
Ever had stillbirth, spontaneous miscarriage or termination	0.5	0.5	1.5	-0.4	-1.2	0.1	0.0	-1.1	-1.0	-0.9	-0.1	-0.4	1.0	0.6	0.3	-1.0	-0.1	-0.2	-0.9	0.1	0.8	-0.9	-0.2	-1.0	-1.0	0.4	-1.2	0.0
Medication: Lisinopril	0.5	0.7	1.8	1.2	0.6	1.1	0.9	0.6	0.5	0.8	0.8	0.7	1.2	0.6	0.9	0.6	1.1	1.0	0.7	0.9	1.4	0.5	0.7	0.6	0.3	0.7	0.4	0.9
Prostate Cancer	0.4	0.6	2.9	-0.4	0.3	-0.9	-0.8	0.6	0.5	0.3	-0.8	-0.7	-1.7	-1.4	-0.8	0.5	-0.4	-0.5	0.2	-1.0	0.3	-0.0	-0.7	0.2	0.5	-1.4	0.9	-0.9
Rheumatoid Arthritis	0.4	0.5	2.7	-0.1	-0.5	0.4	0.8	-0.4	-0.0	-0.4	0.7	0.0	1.6	1.3	1.3	-0.1	0.8	0.8	-0.5	0.8	0.8	-0.0	0.5	-0.2	-0.2	1.3	-0.7	0.6
Neuroticism	0.4	1.1	2.6	-1.0	-0.6	-0.5	-0.4	-1.1	-1.2	-1.2	-0.9	-1.1	-0.5	-0.4	-0.8	-1.6	-1.4	-1.1	-1.2	-0.7	0.6	-1.1	-1.1	-1.4	-1.5	-0.6	-1.1	-1.1
Chronotype (morning person)	0.4	0.8	4.1	1.1	0.6	0.9	0.4	0.9	1.0	1.1	1.0	0.8	1.3	0.5	0.5	0.3	0.2	0.8	1.2	0.7	-2.0	0.5	0.7	0.6	1.2	-0.0	1.2	0.7
Other serious medical condition/disability diagnosed by doctor	0.4	0.6	2.2	0.6	1.1	0.1	-0.1	1.4	1.2	1.1	0.4	0.3	-0.1	-0.4	0.0	0.8	0.0	0.4	1.1	0.0	0.7	0.2	0.4	0.9	1.4	-0.2	1.5	0.2
Angina	0.4	0.6	1.7	0.3	1.0	0.0	0.5	1.3	0.9	0.7	0.8	0.6	0.8	0.6	0.7	0.9	0.6	0.8	0.6	0.5	1.0	0.4	0.9	0.7	1.1	0.8	0.6	0.8
Diabetes (mother)	0.4	0.5	2.2	0.1	1.4	-0.4	-0.9	1.1	1.2	0.9	0.2	-0.2	-1.1	-0.6	-0.7	0.1	-0.4	0.0	1.2	-0.2	0.0	0.3	-0.4	0.3	0.3	-0.5	1.5	-0.7
Frequency of unenthusiasm / disinterest in last 2 weeks	0.4	0.5	1.9	0.3	0.9	0.3	-0.0	0.3	0.4	0.7	1.2	0.4	0.5	1.4	-0.2	-0.5	-1.2	0.6	0.6	1.1	0.7	-0.5	0.3	-0.9	-0.4	0.8	-0.1	0.0
Heel bone mineral density (BMD) T-score, automated (right)	0.4	0.8	5.4	0.6	-0.0	1.0	1.0	0.4	0.4	0.1	0.8	1.1	1.8	1.1	1.1	-0.1	0.9	0.8	-0.1	1.1	2.3	0.6	0.7	-0.1	-0.3	0.5	-0.3	1.0
Weight	0.4	1.9	4.4	-2.1	-1.6	-1.9	-0.9	-1.8	-1.5	-1.5	-1.2	-1.5	-0.6	-0.7	-0.7	-1.4	-1.5	-1.2	-1.2	-1.5	1.1	-1.7	-1.0	-1.6	-1.3	-0.8	-1.1	-1.3
Falls in the last year	0.4	0.5	1.7	-0.0	1.2	-0.4	-0.2	0.9	1.0	0.9	0.8	1.2	0.1	0.4	-0.2	0.8	-0.3	0.5	0.9	0.4	1.3	0.1	0.5	0.1	0.7	0.6	0.7	0.2
Illnesses of mother	0.4	0.5	1.8	-0.9	-1.3	-0.6	0.3	-1.1	-1.3	-0.9	-0.6	-0.3	0.6	-0.1	0.3	-0.1	-0.5	-0.4	-1.1	-0.4	0.4	-0.8	-0.2	-0.6	-0.9	-0.4	-1.3	-0.3
Pulse wave Arterial Stiffness index	0.4	0.4	1.3	-0.1	-0.7	0.3	1.1	-0.1	-0.1	-0.5	0.5	0.2	0.5	1.1	1.1	0.6	0.4	0.6	-0.8	0.7	0.1	-0.1	1.0	-0.1	-0.4	0.9	-0.8	0.6
Length of working week for main job	0.4	0.4	1.6	-0.2	0.9	-0.6	-0.6	0.8	1.0	0.8	0.7	1.0	-0.3	0.3	-0.4	-0.1	-1.2	0.4	1.1	0.3	-0.8	-0.5	0.3	-0.4	-0.1	0.5	0.8	0.4
Pulse wave reflection index	0.4	0.5	1.5	-0.8	-0.9	-0.6	-0.5	-0.5	-0.3	-0.8	-0.4	-0.8	-0.1	-0.0	-0.6	-0.8	-0.1	-0.6	-0.9	-0.3	1.1	-0.2	-0.5	-0.9	-1.2	-0.5	-0.6	-0.9
Glaucoma (self-reported)	0.4	0.4	1.8	0.3	0.3	0.4	0.7	0.5	0.5	0.4	0.7	1.2	0.5	0.8	0.8	0.6	0.2	0.9	0.3	0.9	1.3	0.5	0.8	0.1	-0.1	0.7	-0.0	0.7
Hypothyroidism/myxoedema (self-reported)	0.4	0.7	3.0	0.4	0.5	0.3	0.6	0.8	0.6	0.4	1.0	1.2	1.7	1.2	0.2	0.8	0.6	0.7	0.6	1.1	1.1	-0.5	1.1	0.1	0.4	1.5	-0.0	0.6
Worry too long after embarrassment	0.4	0.7	2.8	-0.2	-0.1	-0.2	-0.8	-0.3	-0.1	0.0	-0.5	-1.2	-0.8	-0.7	-0.9	-1.0	-1.2	-0.6	-0.1	-0.6	1.7	-0.5	-1.1	-0.9	-0.9	-1.2	0.2	-1.2
Eye problems/disorders: None of the above	0.4	0.4	1.5	0.9	1.0	0.5	-0.7	0.8	0.9	1.0	-0.1	-0.2	-0.6	-0.9	-0.8	-0.2	0.5	-0.1	0.8	-0.2	-0.5	0.4	-0.4	0.6	0.1	-0.6	1.2	-0.2
Whole body fat mass	0.4	1.5	3.6	0.5	0.6	0.7	1.4	0.5	0.5	0.6	1.7	1.3	1.5	1.8	1.6	1.1	1.1	1.6	0.7	1.3	1.9	0.6	1.7	0.9	1.2	1.6	0.2	1.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.4	0.5	1.8	0.2	1.3	-0.3	-0.9	0.8	1.3	1.0	0.2	0.2	0.1	-0.5	-1.1	-0.6	-0.3	-0.2	1.3	-0.0	0.9	0.2	-0.3	-0.2	0.3	-0.2	1.3	-0.6
Mood swings	0.4	0.7	2.7	-0.3	-0.7	0.6	0.4	-0.9	-1.0	-1.0	0.2	-0.3	1.0	1.1	0.1	-1.2	-0.3	-0.2	-1.1	0.6	-0.5	-0.6	-0.3	-1.4	-1.6	0.6	-1.4	-0.3
Qualifications: nursing, teaching	0.4	0.7	2.3	-0.6	0.0	-1.0	-1.0	0.3	0.4	0.3	-0.9	-0.7	-1.5	-1.5	-0.9	-0.0	-1.3	-0.7	0.3	-1.1	0.6	-0.6	-0.8	-0.3	-0.2	-1.5	0.9	-0.7
Illnesses of father: None of the above (group 1)	0.4	0.5	1.6	-0.7	-1.0	-0.3	-0.0	-1.3	-0.8	-1.0	-0.8	-0.9	0.1	-0.4	-0.0	-0.4	-0.4	-0.5	-1.2	-0.6	-0.6	-0.3	-0.6	-0.6	-1.0	-0.3	-0.9	-0.7
Arm fat mass (left)	0.4	1.8	4.5	0.8	1.1	0.7	1.4	1.0	1.0	1.1	1.8	1.4	1.3	1.5	1.5	1.4	1.0	1.6	1.3	1.3	2.1	0.9	1.8	1.2	1.5	1.2	0.8	1.4
Miserableness	0.4	0.6	2.9	-0.5	-0.3	-0.1	-0.8	-0.2	0.1	-0.5	-0.3	-0.6	0.4	0.1	-1.2	-1.6	-1.2	-0.7	-0.3	0.0	0.1	-0.7	-1.0	-1.7	-1.3	0.1	-0.4	-1.1
Medication: Blood pressure	0.4	0.7	2.6	0.1	1.1	-0.6	-1.0	1.1	1.1	0.6	-0.4	-0.3	-1.6	-1.2	-1.1	0.5	0.4	-0.5	0.6	-0.7	0.1	0.4	-0.4	0.9	0.4	-1.3	1.4	-0.7
Medication: Paracetamol	0.4	0.6	2.2	0.7	1.5	0.4	-0.6	0.8	1.5	1.1	0.4	0.8	0.1	-0.2	-0.8	-0.8	-0.3	0.2	1.2	0.5	1.1	0.6	-0.4	-0.5	-0.0	0.0	1.2	-0.2
Depression (Nagel 2018)	0.3	0.4	1.4	0.3	1.0	0.1	-0.9	0.6	0.9	0.8	0.5	0.3	-0.2	0.3	-1.2	-1.0	-1.0	0.0	0.8	0.6	-0.0	-0.1	-0.5	-1.0	-0.6	0.2	0.5	-0.8
Worry (Nagel 2018)	0.3	0.6	1.7	1.1	1.3	1.3	0.7	1.2	1.0	0.8	0.7	0.6	0.0	0.4	0.3	-0.1	0.2	0.7	0.5	1.0	0.8	1.3	0.1	0.1	-0.3	0.6	0.5	0.1
Neuroticism (2016)	0.3	0.5	1.8	-0.2	-0.7	0.3	-0.3	-0.6	-0.8	-0.9	-0.4	-0.2	0.5	0.1	-0.4	-1.2	-0.2	-0.6	-0.9	-0.0	-0.0	-0.9	-0.7	-1.1	-1.3	-0.0	-1.0	-0.5
Triglycerides	0.3	0.4	1.7	0.8	1.3	0.8	-0.0	0.7	1.0	0.6	0.7	0.6	0.7	0.6	0.2	-0.6	0.6	0.6	0.4	0.8	1.2	0.2	0.2	-0.0	-0.4	0.5	0.3	0.2
Blood Eosinophil Count	0.3	2.0	6.7	-1.0	-2.5	-0.0	-0.0	-2.5	-2.6	-2.3	-1.0	-1.2	-0.8	0.2	0.3	-1.8	0.1	-0.8	-2.1	-0.5	0.2	-1.8	-0.8	-0.9	-1.4	0.9	-2.2	-0.2
Smoking Status	0.3	0.8	2.5	-0.3	-0.6	0.4	1.1	-0.8	-0.8	-0.9	0.5	0.1	1.4	1.4	1.6	-0.1	0.4	0.7	-1.0	0.7	0.7	0.0	0.7	-0.1	-0.3	1.4	-1.4	0.9
Lung FEV1/FVC ratio	0.3	1.4	3.8	1.4	1.2	1.2	1.1	2.0	1.8	1.4	0.9	1.5	0.3	0.3	0.0	1.4	1.0	0.9	1.2	1.1	-1.3	1.0	1.2	1.4	1.2	0.3	1.4	0.8
Average weekly spirits intake	0.3	0.4	4.2	0.1	-0.1	0.3	0.6	-0.1	0.2	-0.4	0.3	0.3	0.9	0.7	0.8	0.3	0.8	0.5	-0.4	0.5	2.0	0.7	0.4	0.3	-0.2	0.5	-0.5	0.3
High blood pressure (mother)	0.3	0.5	2.0	1.0	1.4	0.7	0.2	0.7	0.9	1.0	0.4	0.5	0.2	-0.2	-0.0	-0.0	0.3	0.5	1.1	0.4	0.0	1.2	0.2	0.5	0.7	0.3	1.1	0.5
Impedance of leg (left)	0.3	1.5	4.8	1.5	-0.3	2.2	1.5	-0.2	-0.4	-0.2	1.1	1.0	1.6	1.8	1.6	0.3	1.8	1.1	-0.5	1.7	-0.7	0.7	1.0	0.7	0.2	2.0	-0.9	1.8
Trunk fat mass	0.3	1.3	3.7	0.3	0.1	0.6	1.4	0.1	0.1	0.3	1.6	1.2	1.6	1.9	1.6	0.9	0.9	1.4	0.4	1.2	1.6	0.3	1.7	0.6	0.8	1.7	-0.2	1.3
Past tobacco smoking	0.3	0.5	2.3	-0.1	-0.1	-0.2	-1.0	-0.3	-0.3	-0.4	-0.8	-0.7	-0.7	-0.8	-1.5	-0.9	-0.1	-1.1	-0.3	-0.6	0.2	-0.6	-0.8	-0.7	-1.3	-0.8	-0.2	-0.7
Hearing difficulty/problems with background noise	0.3	0.5	5.7	-0.0	0.0	-0.1	-0.5	-0.1	0.2	0.1	-0.4	-0.6	-0.2	-0.5	-0.6	-1.0	-0.6	-0.3	-0.0	-0.1	2.4	-0.1	-1.0	-0.8	-0.5	-0.5	0.1	-0.7
Diabetes (self-reported)	0.3	0.5	1.5	-0.8	-0.7	-0.3	-0.4	-0.6	-0.9	-1.2	-0.7	-0.6	-0.1	-0.1	-0.4	-0.9	0.6	-0.8	-0.9	-0.6	0.1	-0.8	-0.6	-0.5	-1.0	0.0	-1.0	-0.8
Hayfever/allergic rhinitis (self-reported)	0.3	0.4	1.8	0.9	-0.1	0.9	-0.1	0.8	0.5	0.3	-0.4	0.2	-1.4	-0.8	-0.4	0.2	0.8	-0.4	0.2	-0.1	-0.1	0.8	-0.2	1.0	0.3	-0.9	0.8	-0.2
Neuroticism score	0.3	0.7	2.6	-0.5	-0.1	0.0	-0.4	-0.5	-0.5	-0.6	-0.5	-1.1	0.1	-0.2	-0.7	-1.6	-1.2	-0.6	-0.7	-0.2	0.7	-0.7	-1.1	-1.6	-1.6	-0.3	-0.6	-1.1
Qualifications: A levels/AS levels or equivalent	0.3	0.7	2.5	-0.5	-1.2	-0.5	-0.2	-0.7	-1.0	-0.7	-1.3	-1.4	-0.9	-1.5	-0.1	-0.0	-0.8	-0.9	-0.5	-1.3	0.5	-0.2	-0.9	0.1	-0.4	-1.6	-0.2	-0.4
Medication: Cholesterol lowering	0.3	0.4	1.5	0.6	0.8	0.6	0.6	0.8	0.7	0.4	0.5	0.6	0.7	0.4	0.7	0.4	0.8	0.8	0.4	0.6	1.2	0.3	0.6	0.4	0.2	0.4	0.3	0.7
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.3	1.9	-0.3	-0.2	-0.3	-0.8	-0.6	-0.5	0.0	-0.3	-0.7	-0.2	-0.6	-0.8	-0.5	-0.9	-0.6	0.1	-0.5	1.4	0.0	-0.7	-0.6	-0.2	-0.8	0.1	-0.7
Number of children fathered	0.3	0.3	2.3	-0.5	-0.5	-0.5	-0.4	-0.3	-0.4	-0.3	-0.4	0.4	-1.5	-0.2	-0.5	0.0	-0.3	-0.3	-0.4	-0.3	-1.5	-0.3	-0.2	-0.6	-0.6	-0.1	-0.6	-0.3
Reason for reducing amount of alcohol drunk: Health precaution	0.3	0.4	1.6	-0.5	-0.2	-0.4	-0.5	-1.0	-0.3	-0.5	-0.8	-1.1	-0.0	-0.8	-0.6	-1.3	-0.6	-0.7	-0.3	-0.6	-0.0	-0.4	-0.8	-0.6	-0.3	-0.2	-0.1	-0.7
Medication: Seretide 50 evohaler	0.3	0.4	2.2	0.2	0.6	-0.1	0.5	1.0	1.1	0.6	0.1	0.4	-0.2	-0.2	0.4	1.5	-0.2	0.6	0.7	0.2	-0.3	1.0	0.4	0.6	0.6	-0.4	0.8	0.3
Number of full sisters	0.3	0.3	2.2	-0.4	0.7	-1.0	-0.5	0.5	0.6	0.6	0.3	0.1	0.6	-0.0	0.5	0.0	-0.9	0.6	0.4	-0.2	1.5	-0.8	0.1	-0.3	-0.0	-0.6	0.6	0.2
Suffer from ‘nerves’	0.3	0.5	1.4	-0.4	-0.7	-0.1	-0.6	-0.3	-0.5	-0.6	-0.7	-0.9	-0.7	-0.6	-1.2	-0.6	-0.6	-1.1	-0.7	-0.5	0.7	-0.3	-0.9	-0.9	-1.0	-0.6	-0.3	-1.2
Illnesses of siblings: Diabetes	0.3	0.4	1.6	0.5	1.0	0.1	0.5	1.3	0.7	0.6	0.5	0.5	0.6	0.2	0.5	0.7	0.5	0.7	0.6	0.5	0.9	-0.3	0.8	0.4	0.7	0.6	0.5	0.7
Average weekly champagne plus white wine intake	0.3	0.5	2.6	-0.5	0.5	-0.9	-0.9	0.2	0.3	0.1	-0.7	-0.4	-1.6	-1.0	-0.5	0.0	-0.9	-0.4	0.1	-0.7	-0.2	-0.6	-0.8	-0.3	-0.1	-1.5	0.3	-0.5
Irritability	0.3	0.5	1.1	0.2	1.1	0.3	0.0	0.9	1.0	0.6	1.0	0.9	0.6	0.8	0.6	-0.3	-0.3	0.7	1.0	0.7	0.3	0.9	0.4	-0.1	0.4	0.9	0.7	0.2
Ever depressed for a whole week	0.3	0.4	1.3	-0.2	0.6	-0.5	-1.2	0.5	0.4	0.3	-0.5	-0.1	-0.8	-1.0	-1.1	-0.3	-0.5	-0.7	0.6	-0.7	-0.1	-0.6	-0.7	-0.2	-0.1	-1.0	0.8	-0.8
Leg fat mass (left)	0.3	1.1	4.5	0.5	0.8	0.4	1.0	0.7	0.7	0.8	1.4	1.0	0.8	1.2	1.3	1.1	0.8	1.4	1.0	1.0	2.1	0.8	1.3	1.0	1.2	1.2	0.6	1.1
Reaction Time	0.2	0.3	1.6	-1.1	-0.0	-1.3	-0.5	-0.1	0.0	-0.2	-0.2	-0.4	0.1	-0.3	-0.5	0.0	-1.0	-0.4	-0.1	-0.6	-1.2	-0.2	-0.4	-0.8	0.1	-0.3	0.2	-0.8
Type 2 Diabetes (T2D) (2012)	0.2	0.3	1.1	0.0	0.6	-0.3	0.4	1.0	0.5	0.8	0.7	0.7	0.1	0.5	0.1	0.8	-0.2	0.4	0.6	0.4	-0.5	-0.2	0.9	-0.1	0.1	0.2	0.3	0.7
Blood Red Count	0.2	1.5	3.0	0.8	1.7	0.3	0.7	1.5	1.7	1.4	1.7	0.8	0.2	1.2	1.0	1.3	0.4	1.5	1.5	1.1	1.6	1.2	1.2	1.3	1.6	0.8	1.4	0.9
BMI	0.2	1.3	5.0	1.0	1.2	0.7	0.9	1.2	1.2	1.3	1.1	1.3	-0.0	0.5	0.7	1.0	1.0	1.1	1.1	0.7	2.2	1.4	1.1	1.4	1.4	-0.1	1.3	1.1
Lung FVC	0.2	0.9	3.8	-0.4	-0.4	-0.7	-0.8	0.0	-0.3	-0.5	-1.7	-1.3	-1.4	-2.0	-0.2	-0.5	-0.4	-0.7	-0.6	-1.3	-0.9	-0.2	-1.5	-0.5	-0.9	-1.6	-0.0	-0.9
Tanning	0.2	2.1	7.5	-1.1	-2.6	0.4	-0.5	-1.9	-2.4	-2.5	-0.9	-0.3	-0.4	0.6	-0.1	-1.7	1.0	-1.1	-2.1	-0.1	-1.4	-0.7	-0.6	-1.0	-2.0	0.6	-2.7	-0.5
Systolic blood pressure, automated reading	0.2	0.7	2.1	1.0	1.1	0.7	0.8	1.2	0.8	0.5	0.3	0.5	-0.5	0.2	0.7	1.1	1.5	0.7	0.4	0.7	0.2	1.1	0.7	1.3	0.7	0.5	0.3	1.2
Pack years adult smoking proportion	0.2	0.4	1.8	0.1	-0.3	0.5	0.3	-0.5	-0.5	-0.5	0.2	0.1	0.5	0.8	0.3	-0.7	0.2	0.1	-0.3	0.6	1.4	-0.9	0.0	-0.6	-0.8	1.0	-0.9	0.7
Impedance of leg (right)	0.2	0.9	3.3	1.2	-0.3	1.8	1.1	0.0	-0.2	-0.2	0.7	0.7	1.4	1.1	1.0	0.5	1.5	0.7	-0.5	1.2	-0.7	0.7	0.7	0.7	0.2	1.3	-0.6	1.4
Current tobacco smoking	0.2	0.4	1.4	-0.6	-0.7	-0.2	-0.1	-0.5	-0.6	-0.8	-0.2	-0.4	-0.1	0.4	-0.1	-0.8	-0.6	-0.3	-0.8	0.1	-0.7	-0.6	-0.1	-0.9	-1.2	0.9	-1.0	0.1
Maternal smoking around birth	0.2	0.3	0.9	0.2	-0.6	0.5	0.6	-0.6	-0.6	-0.4	0.4	0.3	0.5	1.0	0.1	-0.2	0.8	0.1	-0.1	0.6	0.9	0.3	0.4	0.1	-0.4	0.8	-0.9	0.4
Chronic bronchitis/emphysema (father)	0.2	0.2	0.7	-0.3	0.4	-0.6	-0.4	-0.2	-0.1	0.1	0.1	-0.1	-0.9	-0.2	-0.8	0.4	-0.7	-0.5	0.5	-0.5	0.6	-0.2	0.0	0.2	0.6	-0.7	0.6	-0.0
Waist circumference	0.2	0.6	2.6	-0.3	-0.5	0.1	1.2	-0.5	-0.7	-0.6	0.5	0.3	1.0	1.1	1.2	0.6	0.9	0.6	-0.5	0.4	1.6	-0.0	1.0	0.5	0.5	1.1	-0.9	0.7
Ever unenthusiastic/disinterested for a whole week	0.2	0.2	1.4	0.2	0.3	0.4	0.2	0.5	0.1	0.2	0.6	0.5	0.7	0.5	0.3	-0.2	-0.1	0.2	0.5	0.3	1.2	-0.2	0.5	0.1	0.3	0.4	0.3	0.7
Qualifications: None of the above	0.2	0.4	2.3	-0.8	0.1	-0.7	-0.6	-0.9	-0.7	-0.8	-0.1	-0.2	0.3	0.5	-0.3	-0.4	-0.4	-0.3	-0.8	-0.1	0.2	-1.5	-0.4	-1.0	-0.7	0.7	-1.0	-0.4
Alcohol intake versus 10 years previously	0.2	0.3	1.2	-0.8	0.2	-1.1	-0.4	-0.1	0.0	-0.2	-0.6	-0.3	-0.4	-0.7	-0.4	0.4	-0.9	-0.3	-0.0	-0.7	-1.0	-0.2	-0.4	-0.4	-0.1	-0.1	0.0	-0.6
Worrier / anxious feelings	0.2	0.4	1.5	0.6	1.2	0.5	0.2	1.1	1.2	0.8	0.1	-0.2	-0.6	-0.3	0.2	-0.2	-0.5	0.5	0.7	0.4	1.0	0.7	-0.3	-0.2	-0.1	-0.2	0.8	-0.2
Medication: Lansoprazole	0.2	0.2	0.7	-0.7	-0.3	-0.6	-0.0	-0.3	-0.3	-0.4	-0.2	-0.4	0.4	0.1	-0.2	-0.1	-0.7	-0.2	-0.3	-0.1	-0.8	-0.3	-0.1	-0.6	0.0	0.7	-0.6	-0.5
Lung cancer (father)	0.2	0.3	1.0	0.2	0.8	-0.0	0.1	0.4	0.8	0.8	0.9	0.5	-0.0	0.6	0.1	0.3	-0.3	0.6	1.0	0.5	0.2	-0.1	0.4	-0.1	0.6	0.4	0.8	-0.1
Headache pain in last month	0.2	0.3	1.0	0.3	0.7	-0.0	-0.2	1.0	1.0	0.8	0.4	-0.1	-0.2	-0.1	-0.4	-0.2	-0.7	0.1	0.7	0.2	0.7	-0.2	0.0	-0.2	0.5	-0.5	1.0	0.1
Medication: Amlodipine	0.2	0.3	1.1	0.5	0.6	0.3	0.1	0.3	0.6	0.7	0.7	0.4	-0.4	0.4	-0.1	0.1	0.1	0.4	1.0	0.4	0.8	0.8	0.3	0.6	0.2	0.3	0.8	0.2
Wheeze or whistling in the chest in last year	0.2	0.3	1.0	0.7	0.3	0.8	0.6	0.2	0.3	0.3	0.5	0.2	-0.4	0.3	-0.1	0.7	0.5	0.2	0.6	0.5	1.0	0.9	0.3	0.8	0.6	0.3	0.4	0.6
Migraine (self-reported)	0.2	0.3	0.8	0.1	-0.6	0.5	0.8	-0.4	-0.6	-0.3	0.4	0.1	0.4	0.9	0.9	0.4	0.5	0.4	-0.9	0.4	0.1	-0.2	0.4	0.0	0.0	0.7	-0.9	0.5
Medication: Omeprazole	0.2	0.2	1.3	0.3	0.6	0.0	-0.3	0.8	0.8	0.3	-0.0	0.5	0.3	-0.2	-0.4	0.2	0.3	0.0	0.4	0.1	1.1	0.8	0.1	0.3	-0.1	0.0	0.5	-0.0
Leg fat mass (right)	0.2	0.8	3.5	0.3	0.8	0.2	0.8	0.7	0.7	0.7	1.0	0.7	0.6	0.8	1.0	1.1	0.7	1.1	0.9	0.7	1.9	0.7	1.1	0.9	1.2	0.8	0.6	0.8
Overall health rating	0.2	0.5	1.7	-0.2	1.3	-0.8	-0.4	1.0	1.0	0.9	0.4	-0.1	-1.0	-0.1	-0.3	0.7	-1.0	0.3	1.3	-0.1	0.5	-0.4	0.0	-0.0	0.8	-0.1	1.1	-0.2
Had major operations	0.2	0.2	0.9	0.4	0.7	0.1	0.0	0.5	0.2	0.6	0.5	0.2	0.1	0.2	0.5	0.4	-0.2	0.5	1.0	0.2	0.8	-0.9	0.3	0.2	0.5	-0.1	0.6	0.7
Medication: Aspirin	0.2	0.3	1.2	0.1	0.9	-0.1	0.6	0.7	0.4	0.6	0.4	0.8	0.6	0.1	0.4	1.1	0.2	0.4	0.4	0.2	1.0	0.2	0.7	0.4	0.7	-0.0	0.4	0.4
Diabetes diagnosed by doctor	0.2	0.4	1.1	-0.8	-0.5	-0.5	-0.5	-0.2	-0.5	-1.0	-0.8	-0.5	0.0	-0.4	-0.5	-0.7	0.3	-0.8	-0.7	-0.7	0.3	-0.7	-0.6	-0.6	-1.0	-0.4	-0.7	-0.8
Eye problems/disorders: Cataract	0.2	0.2	0.8	-0.9	-0.6	-0.5	0.3	-0.6	-0.8	-0.8	-0.3	-0.3	0.3	0.2	0.2	0.2	-0.3	-0.2	-0.9	-0.3	-0.1	-0.7	0.1	-0.3	-0.1	0.1	-0.9	-0.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.2	0.2	0.7	-0.6	-0.4	-0.6	-0.3	-0.4	-0.4	-0.3	-0.6	-0.5	-0.6	-0.7	-0.6	0.0	-0.9	-0.6	-0.2	-0.6	-0.1	-0.5	-0.6	-0.5	0.3	0.1	-0.1	-0.5
Medication: Gliclazide	0.2	0.2	1.4	-0.3	-0.6	0.2	0.0	-0.6	-0.6	-0.7	-0.0	-0.7	0.2	0.4	0.5	-0.6	0.5	-0.0	-0.5	0.0	0.6	-0.0	-0.3	-0.2	0.1	1.2	-0.8	-0.4
Smoking status: Current	0.2	0.3	1.4	-0.4	-0.7	0.0	0.4	-0.4	-0.6	-0.7	0.2	-0.1	0.3	0.8	0.5	-0.4	-0.3	0.1	-0.8	0.4	-0.9	-0.3	0.3	-0.6	-0.8	1.2	-1.1	0.5
Number of self-reported non-cancer illnesses	0.2	0.3	1.2	0.2	0.3	-0.2	-0.3	1.1	1.0	0.6	0.2	-0.0	-0.6	-0.3	-0.7	0.5	-0.0	-0.1	0.7	-0.0	1.0	-0.2	0.2	0.5	0.7	-0.4	1.0	-0.3
Guilty feelings	0.2	0.3	1.3	0.2	0.8	-0.1	-0.9	0.6	0.5	0.6	-0.1	-0.1	0.1	-0.5	-1.2	-0.7	-0.8	-0.4	0.7	-0.1	0.7	-0.2	-0.7	-0.7	-0.3	-0.0	0.6	-0.8
Wears glasses or contact lenses	0.2	0.2	1.2	-0.7	-0.4	-0.7	-0.1	-0.4	-0.1	-0.6	-0.1	-0.3	-0.1	0.3	0.1	-0.2	-0.1	-0.1	-0.8	-0.2	-1.1	-0.8	0.2	-0.3	0.3	-0.1	-0.5	-0.3
Ever taken oral contraceptive pill	0.2	0.2	0.6	-0.1	0.6	-0.5	-0.7	0.2	0.4	0.6	0.4	0.5	0.8	0.0	-0.4	-0.7	-0.5	0.1	0.7	-0.0	0.8	-0.4	-0.0	-0.6	-0.0	0.0	0.6	-0.3
Mother’s age at death	0.2	0.2	0.6	0.7	0.5	0.8	0.6	0.1	0.2	0.4	0.5	0.5	0.2	0.3	0.7	0.7	0.2	0.6	0.3	0.5	0.2	0.7	0.4	0.4	0.6	0.2	0.3	0.5
Ever smoked	0.2	0.4	1.3	-1.1	-1.1	-0.7	0.3	-0.7	-0.7	-0.8	-0.3	-0.3	0.1	0.1	0.8	-0.2	-1.0	-0.0	-0.8	-0.4	-0.7	-0.4	-0.1	-0.6	-0.1	0.4	-0.8	-0.1
Average weekly beer plus cider intake	0.2	0.3	2.0	-0.3	0.2	-0.3	0.1	0.5	0.6	0.3	0.4	0.1	0.7	0.5	0.5	-0.1	-0.8	0.6	0.4	0.5	1.4	-0.2	-0.0	-0.6	-0.2	0.9	0.0	0.2
Risk taking	0.2	0.3	1.9	-0.3	-0.6	0.0	-0.0	-0.4	-0.4	-0.2	0.9	0.8	0.4	1.4	0.5	-0.0	-0.3	0.4	-0.2	0.7	0.6	-0.6	0.4	-0.5	-0.7	0.9	-0.7	0.4
Age started oral contraceptive pill	0.2	0.2	0.9	0.0	-0.4	0.4	0.2	-0.7	-0.7	-0.7	-0.0	0.3	0.9	0.4	-0.3	0.2	0.8	-0.4	-0.8	0.1	-0.5	0.2	0.3	0.3	-0.1	0.2	-0.7	-0.4
Unable to work because of sickness or disability	0.2	0.2	1.6	-0.5	0.4	-0.7	-0.1	0.2	0.1	0.4	0.3	-0.3	0.6	0.0	-0.0	0.6	-0.9	0.1	0.3	-0.2	1.3	-0.1	0.2	-0.3	0.3	-0.2	0.4	0.2
Commuting to job workplace: Cycle	0.2	0.3	1.8	-0.4	-0.2	-0.5	-0.5	-0.2	-0.3	-0.3	-0.7	-0.5	-1.3	-0.8	-0.7	-0.1	-0.7	-0.7	-0.1	-0.6	-0.0	-0.4	-0.6	-0.3	-0.5	-0.4	-0.1	0.0
Vascular/heart problems diagnosed by doctor	0.2	0.5	2.4	-0.6	-1.5	-0.2	0.0	-1.3	-1.5	-0.8	-0.8	-0.7	0.5	-0.5	0.2	-0.2	-0.6	-0.6	-0.9	-0.7	-0.9	-0.3	-0.5	-0.4	-0.4	-0.5	-0.9	-0.2
Medication: Omeprazole (e.g. Zanprol)	0.2	0.2	1.0	-0.1	0.6	-0.4	-0.6	0.7	0.5	0.2	-0.5	0.1	-0.4	-0.8	-0.7	0.4	0.2	-0.4	0.4	-0.5	1.0	0.6	-0.1	0.4	-0.0	-0.4	0.5	-0.2
Pain experienced in last month	0.2	0.4	1.6	-0.2	-0.7	0.2	0.3	-1.0	-0.8	-0.8	-0.5	0.6	0.9	-0.1	0.7	-0.1	1.2	-0.0	-1.0	-0.1	-0.5	0.4	0.3	0.3	-0.8	0.3	-1.0	0.4
Pack years of smoking	0.2	0.3	2.1	0.4	-0.0	0.8	0.5	-0.1	-0.2	-0.3	0.4	0.3	0.4	0.9	0.4	-0.3	0.5	0.3	-0.2	0.7	1.5	-0.5	0.3	-0.2	-0.4	1.1	-0.7	0.8
Neuroticism (Nagel 2018)	0.1	0.3	1.8	0.3	0.2	0.7	-0.0	0.1	-0.0	-0.1	0.2	0.2	0.0	0.4	-0.5	-1.3	-0.8	-0.1	-0.2	0.6	0.5	-0.1	-0.6	-1.2	-1.3	0.3	-0.4	-0.8
Alzheimer’s Disease (in father)	0.1	0.1	0.7	-0.2	0.0	-0.1	-0.2	0.0	0.1	-0.3	-0.1	0.4	0.1	0.1	-0.0	-0.5	0.8	-0.1	-0.6	0.1	0.1	-0.5	0.0	-0.3	-0.6	-0.0	-0.3	-0.0
Crohns Disease (2017)	0.1	0.3	1.7	-0.4	0.6	-0.8	-0.6	0.3	0.2	0.6	-0.2	-0.3	-1.1	-0.7	-0.4	0.3	-1.3	-0.2	0.5	-0.6	0.7	-0.1	-0.2	-0.1	0.5	-0.3	0.8	-0.0
Mean Putamen Volume	0.1	0.1	0.7	-0.1	-0.1	-0.3	-0.1	0.2	-0.1	0.1	-0.4	-0.4	-0.8	-0.7	0.1	0.8	0.0	-0.0	0.2	-0.3	0.1	-0.2	-0.2	0.4	0.5	-0.5	0.1	-0.5
Blood Platelet Count	0.1	0.7	3.6	-0.8	-0.9	-0.4	0.3	-1.9	-1.0	-0.9	-0.6	-1.1	-0.9	-0.0	0.2	-0.4	-0.8	-0.3	-1.2	-0.4	0.5	-0.3	-0.6	-1.2	-0.9	0.3	-1.2	-0.1
Systolic Blood Pressure	0.1	0.5	1.6	0.7	0.8	0.3	0.2	1.3	1.1	0.8	0.3	0.7	-0.7	-0.0	0.3	0.8	0.8	0.6	0.8	0.4	-0.1	1.2	0.5	0.9	0.5	-0.3	0.8	1.0
Type 2 Diabetes (T2D) (2018)	0.1	0.2	1.2	-0.3	-0.2	-0.1	-0.3	-0.0	-0.1	-0.6	-0.6	-0.3	0.1	-0.4	-0.3	-0.4	0.8	-0.4	-0.5	-0.4	1.1	-0.2	-0.6	-0.2	-0.6	-0.4	-0.3	-0.5
Sensitivity / hurt feelings	0.1	0.2	1.4	0.3	-0.1	0.8	1.2	-0.1	-0.6	-0.2	0.2	-0.3	0.4	0.5	0.8	0.2	0.0	0.4	-0.6	0.4	0.3	0.3	0.4	0.1	-0.3	0.1	-0.8	0.5
Relative age voice broke	0.1	0.1	1.6	0.4	0.2	0.3	0.1	0.2	0.5	-0.1	-0.3	-0.0	0.1	-0.2	0.0	0.0	1.3	-0.0	-0.3	0.1	0.3	0.6	-0.1	0.3	-0.0	-0.1	0.0	0.1
Age when periods started (menarche)	0.1	0.2	0.4	0.2	-0.7	0.6	0.1	-0.5	-0.4	-0.4	0.1	0.2	0.3	0.5	0.4	-0.5	0.5	0.1	-0.5	0.3	0.7	0.2	-0.2	-0.3	-0.5	0.5	-0.6	0.1
High blood pressure	0.1	0.2	1.2	0.2	0.7	-0.0	-0.3	0.4	0.8	0.2	0.1	0.1	-1.1	-0.0	-0.4	-0.2	0.6	0.1	0.3	0.1	0.4	0.3	-0.2	0.2	-0.0	-0.2	0.4	-0.3
Supplements: Glucosamine	0.1	0.1	0.4	-0.2	-0.6	-0.4	-0.2	0.4	0.2	0.0	-0.3	-0.2	-0.6	-0.5	-0.3	0.6	0.0	-0.3	0.2	-0.4	0.1	0.2	-0.2	0.5	0.5	-0.3	0.4	-0.5
Alcohol usually taken with meals	0.1	0.2	1.4	0.4	0.3	-0.0	-0.2	0.5	0.3	0.6	-0.0	-0.0	-0.3	-0.6	-0.4	0.7	-0.1	-0.2	0.4	-0.3	0.1	0.7	-0.0	0.7	0.5	-1.2	0.8	-0.4
Frequency of tiredness / lethargy in last 2 weeks	0.1	0.1	0.4	-0.2	0.2	0.0	0.3	-0.1	-0.1	-0.2	0.2	0.1	-0.3	0.5	0.3	0.0	-0.7	0.2	0.0	0.3	0.6	-0.1	-0.1	-0.6	-0.2	0.5	-0.4	-0.0
Hair/balding pattern: Pattern 3	0.1	0.2	1.1	-0.7	0.2	-1.0	-0.6	-0.0	0.0	0.0	-0.1	0.4	0.9	-0.1	-0.6	0.1	-0.8	-0.3	0.1	-0.4	-0.1	-0.1	0.1	-0.3	0.3	-0.2	0.1	-0.2
Prospective memory result	0.1	0.2	0.9	0.4	0.6	0.1	-0.1	0.3	0.5	0.9	0.4	0.1	0.3	0.0	-0.2	0.3	-0.7	0.3	0.5	0.3	-0.7	-0.1	0.0	-0.2	-0.3	0.2	0.5	-0.2
Tense / ‘highly strung’	0.1	0.2	1.5	0.2	0.6	0.3	-0.4	0.6	0.4	0.3	0.1	-0.3	-1.2	-0.1	-1.0	-0.3	-0.6	-0.4	0.4	0.0	0.3	-0.2	-0.6	-0.3	-0.4	0.1	0.5	-0.5
Mouth/teeth dental problems: Bleeding gums	0.1	0.2	0.6	0.4	0.3	0.6	0.7	0.5	0.3	0.3	0.4	-0.4	-0.4	0.4	0.3	0.2	0.3	0.4	0.5	0.4	-0.8	-0.1	0.2	0.3	0.5	0.4	0.2	0.2
Medication for cholesterol, blood pressure or diabetes	0.1	0.1	1.2	-0.2	-0.2	-0.4	0.0	0.0	-0.2	0.2	-0.1	0.2	-0.2	-0.3	-0.3	0.6	-0.3	-0.3	0.1	-0.2	-1.1	0.2	0.1	0.1	0.5	-0.0	0.1	0.1
Medication: Ventolin 100micrograms inhaler	0.1	0.1	0.7	0.2	-0.2	0.4	0.2	-0.4	-0.1	-0.1	0.1	-0.1	0.9	0.4	0.2	-0.0	-0.5	0.2	-0.2	0.4	0.7	0.3	0.1	-0.4	-0.2	0.6	-0.5	0.3
Comparative body size at age 10	0.1	0.3	0.8	-0.4	0.3	-0.8	-0.9	-0.3	0.4	0.2	-0.5	-0.6	-0.9	-0.9	-0.4	-0.3	-0.6	-0.2	0.3	-0.8	-0.3	-0.0	-0.6	-0.2	-0.3	-0.7	0.7	-0.6
Qualifications: College or University degree	0.1	0.4	1.0	-0.6	-0.4	-1.0	-0.6	-0.2	-0.2	-0.2	-0.8	-0.8	-0.7	-1.0	-0.6	-0.2	-0.6	-0.7	-0.4	-0.9	-0.2	-0.9	-0.4	-0.3	-0.6	-1.0	0.1	-0.5
Medication: Blood pressure	0.1	0.2	0.8	0.3	0.7	0.2	-0.4	0.4	0.8	0.3	0.3	0.0	-0.0	0.1	-0.3	-0.5	0.3	0.3	0.4	0.3	0.9	-0.3	-0.2	-0.1	-0.3	-0.2	0.5	-0.2
Mean time to correctly identify matches	0.1	0.2	0.9	-0.9	-0.2	-1.0	-0.4	-0.2	0.1	-0.1	0.0	-0.2	0.2	-0.0	-0.3	0.2	-0.6	-0.1	-0.1	-0.3	-0.9	0.1	-0.2	-0.5	0.4	0.4	0.1	-0.8
Heart disease (mother)	0.1	0.1	0.5	-0.5	0.0	-0.5	-0.3	-0.2	-0.2	-0.4	-0.1	-0.5	-0.0	0.2	-0.7	-0.4	-0.4	-0.5	-0.4	-0.2	0.3	-0.3	-0.1	-0.3	-0.1	0.6	-0.3	-0.3
Supplements: Vitamin C	0.1	0.2	1.2	0.4	-0.3	0.4	0.3	0.4	-0.3	-0.1	0.1	-0.0	0.0	0.3	0.3	0.4	1.1	0.1	-0.2	0.1	-0.4	0.1	0.5	0.8	0.6	-0.1	-0.2	0.4
Knee pain experienced in last month	0.1	0.1	0.6	-0.4	-0.2	-0.6	0.3	0.2	0.4	0.2	0.7	0.1	0.1	0.8	-0.2	0.2	-0.6	0.2	0.2	0.3	0.3	-0.5	0.5	-0.4	0.4	0.5	0.1	-0.1
Hypertension (Self-reported)	0.1	0.2	0.6	0.2	0.7	-0.0	-0.3	0.5	0.8	0.2	0.1	0.2	-0.8	-0.0	-0.3	-0.1	0.7	0.1	0.3	0.1	0.8	0.3	-0.1	0.2	-0.0	-0.1	0.4	-0.3
Smoking status: Previous	0.1	0.2	1.2	0.0	0.1	0.0	0.5	0.1	0.2	0.2	0.4	0.3	0.6	0.3	0.9	0.6	0.3	0.6	0.3	0.2	0.3	0.4	0.3	0.6	1.1	0.2	0.3	0.0
Handedness (chirality/laterality): Left-handed	0.1	0.1	0.8	0.6	-0.0	0.5	-0.0	0.4	0.4	0.4	0.1	0.6	-0.1	-0.0	-0.1	0.0	0.9	0.2	0.1	0.3	0.6	0.4	0.0	0.4	-0.3	-0.3	0.2	0.4
Friendships satisfaction	0.1	0.2	1.0	-0.5	0.4	-0.7	-0.4	0.3	0.3	0.1	-0.4	-0.1	-0.2	-0.4	0.2	-0.3	-1.0	0.2	-0.2	-0.2	-0.6	-0.1	-0.6	-0.6	-0.1	-0.1	-0.1	-0.4
Breast cancer (self-reported)	0.1	0.2	0.8	-0.3	-0.3	0.1	0.3	-0.9	-0.8	-0.7	-0.3	-0.1	0.6	0.0	0.3	-0.2	0.6	-0.2	-0.7	-0.3	-0.4	-0.2	-0.0	-0.0	-0.3	-0.1	-0.7	-0.2
Medication: Bendroflumethiazide	0.1	0.1	0.7	0.3	-0.1	0.4	-0.1	-0.5	-0.4	-0.4	-0.3	-0.1	-0.1	-0.0	0.2	-0.5	0.7	-0.0	-0.4	0.0	0.9	0.4	-0.5	0.2	-0.2	0.1	-0.5	-0.3
Medication: Atorvastatin	0.1	0.2	0.9	0.3	0.5	0.2	0.1	0.9	0.3	0.3	0.2	0.3	0.4	-0.1	0.3	0.4	0.6	0.2	0.4	0.0	0.0	-0.1	0.2	0.3	0.8	-0.1	0.5	0.3
Diastolic blood pressure, automated reading	0.1	0.3	0.7	0.4	0.5	0.2	0.6	0.4	0.3	0.3	0.4	0.2	-0.6	0.3	0.5	0.7	0.3	0.5	0.7	0.4	0.2	0.8	0.6	0.7	0.6	0.7	0.1	0.8
Basal cell carcinoma (self-reported)	0.1	0.1	1.2	-0.0	-0.0	0.1	0.3	0.4	0.3	0.1	0.4	0.2	-0.2	0.3	0.6	0.2	-0.3	0.4	-0.2	0.2	1.1	0.0	0.2	0.1	0.3	-0.1	0.3	0.4
Alcohol drinker status: Previous	0.1	0.1	1.0	-0.4	-0.0	-0.7	-0.2	0.1	0.2	0.2	0.4	0.1	-0.1	0.4	-0.3	0.3	-1.0	0.0	-0.0	0.1	-0.4	-0.4	0.3	-0.5	-0.3	0.4	-0.1	-0.2
Hair Pigment	0.0	0.8	12.5	-0.0	0.5	-0.4	-0.9	0.7	0.7	0.1	-0.4	-0.5	-1.2	-0.6	-1.0	-0.2	-0.4	-0.5	0.1	-0.3	-3.5	-0.0	-0.6	-0.0	0.0	-0.2	0.4	-0.8
Hip circumference	0.0	0.2	0.8	-0.5	0.3	-0.8	-0.4	-0.4	-0.0	0.1	-0.3	-0.3	-0.6	-0.6	-0.2	-0.0	-0.4	-0.2	0.3	-0.8	0.4	-0.1	-0.1	0.0	0.4	-0.9	0.5	-0.3

Hub : Genes

PINLYP

Models

Trait associations