TWAS hub - PLAC9

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1680	0.0390	5.3e-12	0.104	0.113	0.134	0.131	0.149	1.3e-12	1.4e-13	5.6e-16	1.1e-15	1.0e-17
2	GTEx	Adipose Subcutaneous	0.2450	0.0550	2.0e-10	0.144	NA	0.227	NA	0.223	7.4e-12	NA	2.0e-18	NA	4.3e-18
3	GTEx	Artery Aorta	0.1470	0.0560	4.5e-04	0.052	NA	0.063	NA	0.072	7.3e-04	NA	2.2e-04	NA	8.5e-05
4	GTEx	Artery Tibial	0.1455	0.0476	5.8e-05	0.014	NA	0.073	NA	0.039	2.4e-02	NA	2.2e-06	NA	5.0e-04
5	GTEx	Brain Cerebellum	0.1320	0.0590	4.8e-03	0.019	NA	0.012	NA	0.010	9.1e-02	NA	1.4e-01	NA	1.6e-01
6	GTEx	Brain Cortex	0.2860	0.1010	8.5e-04	0.029	NA	0.115	NA	0.087	5.5e-02	NA	4.6e-04	NA	2.2e-03
7	GTEx	Cells Transformed fibroblasts	0.1910	0.0610	1.5e-04	0.140	NA	0.132	NA	0.131	1.1e-10	NA	4.1e-10	NA	4.8e-10
8	GTEx	Esophagus Muscularis	0.1690	0.0640	3.0e-03	0.112	NA	0.082	NA	0.102	2.6e-07	NA	1.1e-05	NA	9.8e-07
9	GTEx	Lung	0.0763	0.0353	4.6e-03	0.055	NA	0.067	NA	0.066	5.0e-05	NA	7.3e-06	NA	9.3e-06
10	GTEx	Muscle Skeletal	0.1916	0.0527	1.1e-05	0.002	NA	0.009	NA	0.011	1.7e-01	NA	3.7e-02	NA	2.4e-02
11	GTEx	Nerve Tibial	0.1741	0.0521	4.6e-06	0.077	NA	0.102	NA	0.110	4.0e-06	NA	1.1e-07	NA	3.7e-08
12	GTEx	Thyroid	0.1070	0.0500	4.5e-03	0.031	NA	0.033	NA	0.047	2.0e-03	NA	1.5e-03	NA	1.5e-04
13	METSIM	Adipose	0.0635	0.0314	4.8e-03	0.000	0.002	0.010	0.008	0.001	2.8e-01	1.6e-01	1.1e-02	2.1e-02	2.1e-01
14	ROSMAP	Brain Pre-frontal Cortex	0.2051	0.0376	0.0e+00	0.173	0.200	0.206	0.213	0.214	1.1e-21	3.6e-25	6.3e-26	6.7e-27	5.5e-27
15	TCGA	Breast Invasive Carcinoma	0.0525	0.0200	9.2e-07	0.020	0.032	0.030	NA	0.028	4.5e-05	3.4e-07	8.3e-07	NA	1.4e-06
16	TCGA	Cervical Squamous Cell Carcinoma	0.1280	0.0490	1.3e-04	0.040	0.101	0.076	NA	0.070	4.7e-03	1.2e-05	1.3e-04	NA	2.5e-04
17	TCGA	Glioblastoma Multiforme	0.1800	0.0810	4.0e-03	0.050	0.059	0.071	NA	0.079	1.3e-02	7.2e-03	3.4e-03	NA	2.2e-03
18	TCGA	Kidney Renal Clear Cell Carcinoma	0.1134	0.0413	2.9e-08	0.061	0.085	0.094	NA	0.069	2.2e-07	8.3e-10	9.7e-11	NA	3.6e-08
19	TCGA	Brain Lower Grade Glioma	0.1210	0.0420	5.5e-11	0.066	0.111	0.106	NA	0.109	5.9e-08	1.6e-12	5.2e-12	NA	2.3e-12
20	TCGA	Lung Adenocarcinoma	0.0757	0.0316	1.1e-04	0.030	0.023	0.015	NA	0.012	1.8e-04	9.0e-04	6.6e-03	NA	1.1e-02
21	TCGA	Lung Squamous Cell Carcinoma	0.0650	0.0300	2.0e-04	0.048	0.025	0.026	NA	0.036	3.3e-06	7.1e-04	5.4e-04	NA	5.1e-05
22	TCGA	Pheochromocytoma and Paraganglioma	0.1090	0.0490	3.0e-03	0.014	0.071	0.023	NA	0.030	8.9e-02	9.0e-04	4.2e-02	NA	2.4e-02
23	TCGA	Prostate Adenocarcinoma	0.0504	0.0236	6.2e-04	0.033	0.045	0.035	NA	0.032	1.9e-04	1.8e-05	1.2e-04	NA	2.2e-04
24	TCGA	Stomach Adenocarcinoma	0.1070	0.0420	2.7e-05	0.100	0.062	0.090	NA	0.094	1.1e-07	2.8e-05	4.8e-07	NA	2.5e-07
25	TCGA	Thyroid Carcinoma	0.1080	0.0380	4.2e-08	0.086	0.100	0.104	NA	0.083	9.6e-09	5.5e-10	2.9e-10	NA	1.7e-08

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25
Prostate Cancer	3.4	4.8	13.5	-2.4	-2.3	-2.6	-2.4	-0.6	-1.0	-2.1	-0.7	-2.3	0.1	-2.2	-1.7	-0.4	-2.0	-2.8	-3.1	-1.8	-3.7	-1.8	-1.8	-2.4	-2.5	-2.6	-2.4	-2.5
Lung FEV1/FVC ratio	3.2	16.4	73.1	6.2	-0.5	0.6	-4.6	8.6	5.6	-2.6	-2.8	2.5	1.5	-1.3	-0.7	0.7	7.9	3.2	3.0	2.8	2.8	6.4	3.8	3.8	2.5	4.8	3.7	3.0
Heart disease (mother)	3.1	3.8	11.2	2.8	1.6	1.0	0.2	1.5	1.3	1.1	-0.4	1.7	0.7	0.7	-0.2	1.2	2.3	2.0	2.0	1.4	3.0	2.5	2.5	3.3	1.9	2.2	3.3	2.4
Fractured/broken bones in last 5 years	3.1	4.0	9.2	-2.6	-1.2	-1.5	-1.2	-2.3	-1.5	-1.3	-1.2	-1.8	-0.3	-1.8	-1.3	-0.6	-2.2	-2.9	-2.3	-0.6	-2.3	-1.9	-2.7	-2.6	-2.7	-2.3	-2.6	-3.0
Bipolar Disorder (2011)	2.9	2.8	6.6	-0.2	-2.5	-2.3	-0.8	1.5	0.8	-2.1	-2.1	-2.1	-2.4	-2.2	-1.8	-2.6	0.6	-2.0	-1.3	-0.1	-1.0	-0.1	-1.1	-1.8	-2.1	-0.3	-1.8	-1.6
Knee pain experienced in last month	2.9	4.5	10.4	0.7	3.2	3.1	2.6	-1.4	-0.0	2.1	1.5	2.6	2.2	2.5	2.0	2.2	0.2	2.4	2.4	1.5	3.0	1.0	0.6	2.3	2.5	1.4	2.3	2.4
Ever had stillbirth, spontaneous miscarriage or termination	2.7	2.8	7.9	-1.1	-2.2	-2.3	-0.4	-0.5	0.6	-1.9	-1.5	-2.3	-0.5	-2.5	-1.5	-2.8	-0.8	-1.7	-1.4	-1.7	-2.1	-0.4	-1.8	-2.0	-1.2	-1.2	-2.0	-1.9
Tinnitus: Yes, now most or all of the time	2.5	2.9	5.9	-1.2	-1.9	-1.9	-0.9	0.8	0.6	-2.3	-2.1	-1.5	-1.5	-2.2	-2.0	-2.1	0.3	-2.0	-2.1	0.4	-1.7	0.0	-2.0	-2.0	-2.4	-1.2	-2.1	-2.0
Medication: Ibuprofen	2.4	2.8	10.3	-1.6	-1.4	-1.4	1.9	-1.8	-1.4	-0.9	-1.4	-2.1	-1.9	-1.3	-1.6	-3.2	-1.4	-1.8	-0.9	-1.1	-1.0	-2.0	-1.5	-2.0	-1.8	-1.0	-1.9	-2.1
Breast cancer (self-reported)	2.4	2.9	8.4	-0.4	-1.9	-2.3	-1.0	1.2	1.1	-2.6	-2.2	-2.0	-0.7	-2.2	-2.7	-1.5	0.4	-1.9	-2.1	1.0	-0.4	0.7	-1.0	-1.9	-2.9	-0.5	-1.9	-1.6
Mean time to correctly identify matches	2.3	4.3	8.7	-2.7	-2.0	-2.2	0.6	-1.5	-0.7	-1.2	-0.8	-2.1	-1.1	-1.8	-0.9	-1.1	-2.2	-2.7	-2.6	-3.0	-2.8	-2.0	-2.9	-2.5	-1.7	-2.5	-2.4	-2.8
Number of full sisters	2.3	2.8	7.0	1.8	1.3	1.4	2.1	0.4	0.5	1.2	0.2	1.3	1.4	1.2	0.6	-1.1	1.5	2.2	2.6	1.5	2.1	1.8	1.1	2.3	2.0	2.5	2.3	2.1
Ever had bowel cancer screening	2.2	2.6	8.2	0.9	-2.3	-2.3	-2.3	2.9	1.9	-2.6	-2.3	-1.3	-1.7	-2.3	-2.5	-0.6	1.7	-0.3	-0.9	-0.6	-0.5	1.5	0.1	0.0	-1.1	1.0	0.1	-0.1
Eye problems/disorders: Glaucoma	2.2	2.6	6.2	-0.8	-2.1	-2.5	-1.7	1.0	1.3	-2.0	-1.5	-1.9	0.8	-2.0	-1.6	-1.6	-0.3	-1.3	-1.4	-2.0	-2.2	-0.1	-1.8	-2.3	-1.1	-0.5	-2.3	-1.4
Diabetes (mother)	2.0	2.6	8.5	2.7	1.0	0.9	-0.5	1.8	2.2	0.0	-1.1	0.7	-0.7	-0.0	-0.3	1.1	2.9	1.4	1.3	2.4	2.2	2.5	1.6	1.6	0.5	2.2	1.6	1.3
Impedance of arm (right)	2.0	9.2	21.4	-4.3	-2.4	-2.8	-0.1	-3.2	-0.5	-1.2	-1.1	-2.3	-1.0	-2.5	-1.7	-2.6	-3.8	-4.6	-4.5	-0.7	-3.5	-3.5	-3.5	-3.4	-4.4	-4.0	-3.3	-3.3
Medication: Ibuprofen (e.g. Nurofen)	2.0	2.5	10.5	-1.2	-1.4	-1.3	1.8	-1.3	-1.4	-1.1	-1.6	-2.0	-1.9	-1.4	-1.6	-3.2	-0.9	-1.6	-0.9	-1.1	-0.9	-1.6	-1.3	-1.8	-1.7	-0.7	-1.8	-1.8
Reaction Time	1.9	3.6	11.5	-2.4	-1.7	-1.9	1.0	-1.2	-1.2	-1.0	-0.4	-1.9	-1.1	-1.4	-0.6	-1.0	-2.0	-2.3	-2.2	-3.4	-2.5	-2.2	-2.5	-2.2	-1.4	-2.2	-2.2	-2.4
Pulse wave Arterial Stiffness index	1.9	2.2	5.7	0.4	2.0	2.1	1.5	-0.9	-0.7	1.5	1.8	1.8	0.1	2.4	1.9	1.2	-0.4	1.9	1.8	0.0	2.2	-0.4	1.1	1.4	1.9	0.9	1.4	1.4
Commuting to job workplace: Cycle	1.9	2.3	7.0	-2.2	-1.6	-1.5	-1.1	-1.4	-1.1	-1.1	-0.5	-1.2	-0.7	-1.3	-0.2	-2.1	-1.8	-1.9	-1.6	-1.8	-2.7	-1.5	-1.1	-1.4	-1.3	-1.8	-1.4	-1.6
Schizophrenia (2018)	1.8	3.7	12.8	-2.9	-2.1	-2.2	-0.9	-1.2	-1.3	-0.1	-0.8	-1.6	-1.4	-1.3	-0.8	-2.4	-2.0	-2.0	-2.9	-1.8	-3.6	-1.3	-2.1	-2.0	-1.5	-2.4	-1.9	-2.1
Impedance of leg (right)	1.8	8.6	18.5	-4.0	-2.6	-3.1	-0.8	-1.6	-0.3	-1.3	-1.1	-2.7	-0.8	-2.0	-1.4	-3.7	-3.1	-4.0	-3.7	-2.1	-3.5	-3.6	-3.1	-4.3	-3.9	-3.1	-4.3	-3.3
Pulse wave peak to peak time	1.8	2.1	5.3	-0.4	-1.9	-2.0	-1.5	0.8	0.5	-1.4	-1.7	-1.9	-0.0	-2.3	-1.8	-1.0	0.3	-1.9	-1.8	-0.1	-2.1	0.3	-1.0	-1.4	-1.8	-0.8	-1.4	-1.4
Illnesses of father: Heart disease	1.8	2.5	15.1	-0.2	2.4	2.0	3.9	-2.2	-0.4	2.1	1.3	1.5	2.0	1.9	1.4	0.4	-1.3	0.7	1.2	0.7	1.6	-0.4	-0.6	0.9	2.0	-0.6	0.9	0.2
Commuting to job workplace: Walk	1.8	1.9	7.6	-1.0	1.4	0.9	1.5	-2.8	-1.7	1.7	1.7	0.5	1.4	2.1	1.4	0.1	-2.5	0.7	1.0	-1.4	-0.3	-1.4	-0.5	0.7	1.9	-0.7	0.8	0.7
Rheumatoid Arthritis	1.7	2.4	10.1	-2.5	-0.4	-0.1	1.9	-2.8	-0.6	-0.1	-0.9	-1.3	-0.5	-0.5	-0.1	-1.1	-1.9	-1.9	-1.5	-1.6	-1.4	-1.7	-3.2	-0.6	-0.8	-2.4	-0.6	-1.8
Age at First Birth	1.6	2.3	7.8	1.9	-2.0	-0.9	-2.2	2.8	1.6	-1.8	-1.5	-1.2	-2.6	-1.5	-1.4	-0.8	2.6	0.6	0.3	1.0	0.1	1.7	0.9	0.2	-0.5	1.7	0.1	0.4
Impedance of arm (left)	1.6	7.5	17.0	-4.0	-2.3	-2.5	-0.0	-2.9	-0.7	-0.7	-0.6	-2.3	-0.4	-2.1	-1.3	-2.6	-3.7	-4.1	-3.9	-0.9	-3.2	-3.5	-3.2	-2.9	-4.0	-3.5	-2.9	-2.9
Osteoarthritis (self-reported)	1.6	2.1	5.2	1.0	1.5	1.5	-0.2	-0.5	2.3	0.1	-0.1	2.0	1.0	0.8	0.6	1.3	0.9	1.6	2.0	0.9	1.5	1.3	0.9	2.3	1.5	1.7	2.3	2.1
Crohns Disease (2017)	1.5	3.3	10.7	-0.4	-2.8	-3.2	-3.2	2.2	1.2	-3.3	-2.1	-1.3	-1.1	-2.9	-2.7	-0.9	0.5	-1.7	-1.3	-0.5	-2.0	1.1	-0.6	-0.6	-1.4	-0.5	-0.6	-0.6
Coronary Artery Disease (CAD)	1.5	1.8	7.0	-0.9	2.7	1.6	1.1	-0.7	0.4	1.3	0.5	2.3	-0.1	1.8	1.0	1.5	-1.0	0.8	0.2	2.0	1.5	0.9	1.0	1.8	1.1	-0.1	1.8	1.7
Crohns Disease (2012)	1.5	2.3	6.9	-1.5	-1.6	-1.7	-1.6	0.5	-0.5	-1.5	-0.4	-0.7	-0.7	-1.7	-0.8	-0.5	-0.9	-2.6	-2.5	-0.2	-2.4	-0.7	-1.5	-1.6	-1.9	-2.3	-1.6	-2.1
Type 2 Diabetes (T2D) (2012)	1.5	1.7	6.7	-1.3	0.7	0.5	0.0	-1.2	-2.5	1.4	1.2	1.0	0.3	0.9	1.2	1.6	-1.9	-0.9	-2.0	-1.2	-2.3	-1.4	0.2	0.1	0.1	-2.6	0.2	-0.3
Tinnitus: Yes, but not now, but have in the past	1.5	1.6	5.2	0.9	1.6	1.4	1.2	-1.2	0.6	0.8	0.7	0.5	1.1	1.3	0.5	1.7	0.2	1.8	2.3	-1.0	1.4	0.0	-0.2	1.3	2.2	1.4	1.3	1.2
Impedance of leg (left)	1.5	7.3	14.8	-3.9	-2.2	-2.8	-0.8	-1.7	-0.9	-1.1	-0.8	-2.2	-0.5	-1.7	-1.1	-3.0	-3.0	-3.8	-3.8	-1.5	-3.2	-3.3	-2.9	-3.8	-3.8	-3.2	-3.7	-2.9
Waist circumference	1.5	5.4	16.1	2.5	2.8	2.1	1.8	0.2	1.7	0.7	0.1	1.4	0.8	1.4	0.2	1.9	1.6	3.0	4.0	0.9	3.6	2.4	1.2	3.2	3.5	3.1	3.2	3.3
Prospective memory result	1.5	1.9	8.6	1.6	-0.6	-0.7	-1.7	2.9	2.6	-1.1	-1.1	0.8	-0.3	-0.6	-0.8	0.2	2.2	1.0	1.1	1.0	1.0	1.8	1.5	0.5	0.2	2.1	0.5	1.3
Birth weight of first child	1.5	2.8	14.2	-0.3	-2.3	-2.6	-3.8	3.0	1.5	-2.4	-1.3	-1.3	-1.8	-2.1	-1.5	-0.7	0.3	-1.3	-0.9	-0.8	-1.3	-0.1	0.8	-1.0	-2.1	-0.0	-0.9	-0.1
Ever highly irritable/argumentative for 2 days	1.5	1.8	8.4	2.2	0.4	0.3	0.1	1.6	2.9	-1.2	-1.4	0.5	-0.7	-0.6	-1.3	0.3	2.3	0.8	0.7	1.1	1.1	2.3	1.2	1.3	0.5	1.3	1.3	1.2
Birth weight	1.5	3.3	11.9	2.5	-0.2	-0.0	-3.0	3.4	1.1	-1.1	-0.7	0.4	-2.0	-0.2	-0.1	1.7	3.1	1.4	1.3	1.8	0.9	2.4	2.9	1.5	0.4	2.2	1.4	2.0
Neck or shoulder pain in last month	1.5	2.1	6.2	-0.6	-1.9	-1.8	-2.0	0.4	1.5	-1.9	-1.1	-2.3	0.4	-1.7	-1.6	-1.3	0.1	-0.7	0.4	-1.0	-0.6	-0.7	-1.4	-2.4	-1.3	0.8	-2.5	-1.3
Medication: Omeprazole	1.5	1.8	4.9	-1.7	-1.0	-1.5	-0.9	-0.9	-0.6	-1.5	-0.5	-1.7	-0.1	-1.2	-1.6	-0.5	-1.3	-1.5	-0.6	-0.7	-0.6	-1.8	-1.4	-2.2	-2.1	-0.5	-2.2	-1.7
Commuting to job workplace: Car/motor vehicle	1.5	1.8	6.3	1.3	-0.4	-0.5	0.1	2.5	2.5	-1.1	-1.5	0.7	-0.8	-0.7	-1.1	0.2	1.8	0.7	1.2	1.0	1.6	1.6	1.4	1.3	-0.1	2.2	1.3	1.4
Mouth/teeth dental problems: Mouth ulcers	1.5	2.4	8.0	-2.6	1.1	0.4	1.5	-2.6	-1.7	1.6	1.8	0.6	0.2	1.6	1.1	0.1	-2.8	-1.0	-0.3	-2.2	-0.9	-2.4	-0.8	-1.2	0.3	-2.1	-1.1	-0.8
Mineral and other dietary supplements	1.5	2.0	5.2	1.8	1.6	1.6	1.0	1.0	-0.7	1.7	0.6	1.9	1.1	1.5	1.5	0.0	1.6	1.5	0.9	1.7	1.6	1.6	2.3	1.5	1.6	0.8	1.5	1.1
Average weekly champagne plus white wine intake	1.5	2.1	5.5	-1.1	-1.5	-1.2	-0.3	-0.7	-0.9	-0.0	-0.1	-1.9	-0.9	-0.9	-0.8	-2.3	-1.2	-1.7	-1.4	-0.2	-2.0	-1.6	-1.4	-2.3	-1.6	-1.5	-2.3	-2.1
Average weekly beer plus cider intake	1.5	2.2	9.8	2.0	1.0	1.1	0.0	1.4	0.9	0.8	0.1	0.9	1.1	0.8	0.0	0.8	1.9	2.3	2.1	0.8	1.8	1.3	1.9	1.3	0.9	3.1	1.3	2.2
Impedance of whole body	1.5	7.9	17.3	-4.1	-2.3	-2.7	-0.3	-2.5	-0.8	-0.8	-0.6	-2.1	-0.3	-1.9	-1.2	-2.7	-3.5	-4.2	-4.1	-1.2	-3.4	-3.6	-3.1	-3.4	-4.1	-3.6	-3.3	-2.9
Ever used hormone-replacement therapy (HRT)	1.4	1.8	5.9	-1.2	-1.0	-0.9	2.2	-1.6	0.8	-0.6	-0.7	-1.2	-0.4	-1.4	-1.3	-0.8	-1.2	-1.7	-1.2	-1.5	-1.2	-0.7	-2.4	-1.5	-0.7	-1.6	-1.5	-2.2
Body mass index (BMI)	1.4	6.1	15.9	3.0	2.5	1.8	0.4	1.3	1.8	0.6	-0.1	1.6	0.9	1.2	0.2	2.2	2.5	3.1	4.0	1.7	3.8	3.0	1.8	3.4	3.3	3.4	3.4	3.4
Hair/balding pattern: Pattern 2	1.4	1.7	5.8	2.4	-0.3	0.3	0.7	1.9	1.8	0.2	-0.7	-0.5	1.0	-0.1	-0.5	-0.9	1.9	1.4	1.8	0.7	1.2	1.4	1.3	1.3	1.0	2.3	1.3	1.5
Mouth/teeth dental problems: Bleeding gums	1.4	1.8	6.1	0.6	2.5	1.7	1.3	-0.0	0.5	2.4	1.3	1.9	0.9	1.6	1.1	0.9	-0.1	1.2	0.8	1.9	1.6	0.9	1.2	1.1	1.6	0.1	1.1	1.1
Glaucoma (self-reported)	1.4	1.7	4.8	-0.9	-1.6	-2.2	-0.6	0.6	1.1	-1.8	-1.2	-1.3	-0.1	-1.8	-1.3	-1.0	-0.3	-1.4	-1.6	-1.0	-2.2	0.3	-1.2	-1.5	-1.2	-0.7	-1.4	-0.8
Leg pain on walking	1.4	1.7	5.1	1.0	1.4	1.5	1.1	-0.2	-0.0	1.2	1.4	1.0	1.4	1.5	1.4	0.7	0.3	1.7	2.3	-1.1	1.8	0.0	0.9	1.3	2.1	1.2	1.4	1.8
Deep venous thrombosis (DVT) (self-reported)	1.4	1.8	7.4	1.9	-0.8	-0.7	-1.1	2.7	2.0	-0.9	-1.4	-0.3	-0.2	-1.2	-1.5	-0.2	2.0	0.4	0.5	2.4	0.7	2.1	1.2	0.6	-0.3	1.7	0.5	0.6
Frequency of unenthusiasm / disinterest in last 2 weeks	1.3	1.8	6.1	2.2	0.1	0.5	0.2	1.8	1.8	-0.5	-0.7	0.7	-1.6	-0.2	-0.5	0.4	2.3	1.3	1.2	1.2	1.2	2.5	1.2	1.6	1.0	1.6	1.6	1.3
Blood clot in the leg (DVT)	1.3	1.7	6.5	2.0	-0.8	-0.6	-0.7	2.5	1.8	-0.8	-1.4	-0.4	-0.2	-1.1	-1.5	-0.2	2.1	0.6	0.5	2.4	0.7	2.1	1.1	0.7	-0.1	1.8	0.6	0.5
Reason for reducing amount of alcohol drunk: Health precaution	1.3	1.5	5.3	1.6	-0.4	-0.4	-1.2	2.0	1.6	-1.3	-1.6	-0.2	0.0	-1.2	-0.9	-0.1	2.3	0.5	0.6	2.1	1.2	2.0	0.9	0.8	-0.2	1.6	0.7	0.7
Loneliness, isolation	1.3	1.8	9.6	-1.3	-1.2	-1.2	1.2	-0.6	0.8	-0.6	-0.2	-1.4	-1.6	-1.1	-1.2	-1.1	-1.0	-0.8	-0.4	-3.1	-1.3	-1.0	-2.1	-1.9	-0.1	-0.8	-1.9	-1.8
Medication: Omeprazole (e.g. Zanprol)	1.3	1.6	4.4	-2.1	-0.6	-1.0	-0.7	-1.3	-1.1	-0.9	0.0	-1.2	0.5	-0.7	-0.9	0.3	-1.7	-1.3	-0.7	-1.3	-0.9	-2.0	-1.6	-2.0	-1.7	-0.9	-2.0	-1.5
Heart disease (siblings)	1.3	1.6	4.5	-0.7	-1.3	-2.0	-0.5	1.2	1.0	-2.1	-1.9	-1.5	-2.0	-1.6	-2.1	-1.8	0.0	-1.0	-0.6	-0.9	-0.2	0.1	-1.0	-0.6	-0.7	-0.3	-0.6	-0.9
Alcohol drinker status: Previous	1.3	1.5	5.6	-1.7	-0.8	-0.8	-0.7	-1.5	-0.8	-0.1	0.1	-1.5	0.8	-0.5	-0.2	-0.7	-1.2	-1.4	-0.6	-1.8	-1.5	-1.8	-2.4	-1.3	-1.0	-1.2	-1.3	-1.7
Ovarian Cancer	1.2	1.6	3.3	1.3	1.7	1.5	0.1	0.5	1.3	0.9	0.2	1.7	-0.2	0.9	0.9	1.8	1.3	1.3	0.9	1.3	1.7	1.6	1.2	1.7	1.3	0.9	1.7	1.4
Qualifications: CSEs or equivalent	1.2	1.6	3.8	1.2	1.9	0.9	-0.8	1.3	0.2	0.4	0.5	1.9	-0.1	1.4	0.3	1.3	1.3	1.5	1.5	1.2	1.7	1.2	1.9	1.0	1.5	1.4	1.0	1.6
Comparative body size at age 10	1.2	3.4	8.5	2.9	1.2	1.4	-1.1	2.5	2.2	0.9	0.2	0.9	-0.1	1.0	0.4	1.4	2.7	2.3	2.0	1.6	2.1	2.4	2.6	2.0	1.4	2.4	2.0	2.4
Arm predicted mass (right)	1.2	5.9	15.1	3.0	2.1	2.3	1.0	1.3	-0.5	1.8	1.6	1.4	0.8	2.4	1.8	2.1	1.8	3.9	3.9	0.1	2.9	2.0	3.2	2.6	3.6	3.2	2.6	3.3
Arm fat mass (left)	1.2	5.0	13.4	2.4	2.4	1.7	0.7	0.6	1.4	0.9	0.1	1.4	0.9	1.3	0.4	2.3	1.6	2.9	3.7	1.6	3.5	2.3	1.8	3.1	3.0	3.0	3.1	3.5
Mother’s age at death	1.2	1.5	5.2	1.7	-0.8	-0.2	-2.3	2.2	2.1	-0.8	-1.1	0.0	-0.8	-0.9	-0.6	0.0	2.1	0.5	0.3	0.9	0.4	1.6	1.0	1.4	-0.0	1.2	1.4	0.9
Irritable Bowel Disease (IBD)	1.1	2.7	11.1	-0.9	-2.3	-2.6	-3.3	2.1	0.9	-2.9	-1.2	-1.3	-0.5	-1.9	-1.7	0.0	0.1	-1.8	-1.2	-1.9	-2.0	0.1	-1.0	-1.1	-1.2	-1.1	-1.0	-0.8
Systolic Blood Pressure	1.1	5.7	33.9	-3.7	0.9	0.2	3.9	-5.8	-3.8	0.9	1.1	-0.6	0.7	0.6	0.5	-1.2	-4.4	-1.4	-0.4	-2.1	-1.2	-3.2	-3.3	-1.6	0.1	-2.3	-1.6	-1.5
Number of treatments/medications taken	1.1	1.9	8.6	-2.4	0.2	0.1	1.0	-2.9	-1.2	-0.3	-0.2	-0.6	-1.1	-0.3	-0.2	0.0	-2.3	-1.5	-0.9	-1.0	-1.0	-2.0	-2.2	-1.2	-0.9	-1.9	-1.2	-1.8
Diabetes (father)	1.1	1.3	4.9	-2.0	0.4	-0.6	0.2	-2.0	-0.7	0.4	0.8	0.1	2.0	0.1	0.3	1.0	-2.2	-1.0	-1.3	-1.1	-1.0	-1.7	-0.8	-1.1	-0.8	-1.5	-1.0	-0.6
Maternal smoking around birth	1.1	1.6	6.0	1.2	1.8	1.7	2.5	-0.8	-0.9	1.7	1.0	0.6	1.1	1.5	1.3	0.3	0.5	1.5	2.3	-1.1	1.2	0.4	0.3	0.3	2.2	1.0	0.3	0.7
Heel bone mineral density (BMD) T-score, automated (left)	1.1	2.5	11.7	2.6	-0.4	-0.1	0.1	3.4	1.5	-0.8	-1.7	0.4	-0.3	-0.9	-1.1	-1.3	3.2	0.7	1.2	2.0	2.1	2.4	1.0	1.3	0.4	1.9	1.3	0.3
Leg predicted mass (left)	1.1	5.6	13.3	2.8	2.2	2.4	1.2	0.7	-0.0	1.8	1.6	1.4	0.8	2.1	1.6	2.6	1.4	3.6	3.7	0.7	3.0	1.9	3.0	2.9	3.4	3.0	2.9	3.4
Had other major operations	1.1	1.4	3.7	-1.4	-1.1	-1.1	-1.1	-0.3	0.1	-0.9	0.3	-1.4	0.7	-0.6	-0.5	-0.5	-1.0	-1.5	-1.0	-1.2	-0.9	-1.9	-0.8	-1.9	-1.8	-1.1	-1.9	-1.4
Medication: Simvastatin	1.1	1.6	4.2	1.2	1.8	1.3	1.1	-0.2	1.2	0.9	-0.4	1.0	-0.0	1.3	0.4	-0.2	0.5	1.5	1.9	0.3	1.3	1.2	0.5	2.0	1.8	1.4	2.0	1.9
Alcohol intake versus 10 years previously	1.1	1.7	5.4	0.8	1.4	1.2	1.0	0.2	0.5	0.8	0.2	1.8	0.6	0.9	0.5	2.3	0.8	1.6	1.7	0.0	2.2	0.9	1.1	1.5	1.4	1.7	1.5	1.8
Happiness	1.1	1.3	5.4	0.7	-1.2	-0.9	0.1	1.3	2.3	-1.9	-1.8	-1.1	-1.1	-1.8	-1.4	-1.1	1.7	-0.6	0.4	-0.5	0.4	1.0	-0.9	-0.7	-0.6	0.7	-0.7	-0.8
Serious illness, injury or assault of a close relative in last 2 years	1.1	1.3	3.6	-0.1	1.4	0.9	0.8	-0.6	1.1	1.3	1.7	1.0	1.3	1.3	1.0	1.9	-1.1	-0.1	0.9	1.2	0.3	-0.2	1.1	1.7	0.8	-0.9	1.7	1.3
Number of full brothers	1.1	1.4	4.1	0.5	1.3	1.8	0.7	-0.6	-0.3	1.3	1.9	1.2	1.1	2.0	1.7	-0.1	-0.4	1.0	1.6	0.6	1.2	-0.5	1.7	0.8	0.8	0.7	0.8	1.4
Age at last live birth	1.1	1.7	3.7	-1.0	-1.9	-1.8	-1.5	-0.3	-0.4	-1.8	-1.0	-1.6	-0.4	-1.9	-1.2	-1.0	-0.7	-1.4	-1.4	-0.8	-1.7	-0.6	-1.5	-1.1	-1.1	-1.3	-1.1	-1.5
Qualifications: NVQ or HND or HNC or equivalent	1.1	1.4	6.0	1.6	-0.7	-0.7	-1.1	2.4	0.8	-0.7	-1.0	-0.3	-0.2	-0.6	-0.8	-0.8	2.0	0.6	1.4	0.6	1.5	0.9	2.0	-0.3	-0.2	2.2	-0.3	0.7
Leg fat-free mass (right)	1.1	5.7	12.0	2.7	2.3	2.5	1.2	0.5	-0.4	1.8	1.8	1.6	1.0	2.2	1.8	3.0	1.4	3.5	3.4	1.0	3.0	1.9	3.0	3.1	3.2	2.7	3.0	3.3
Qualifications: nursing, teaching	1.1	1.7	4.3	-0.7	-2.1	-1.3	-0.5	0.3	1.1	-1.4	-1.3	-1.7	-1.8	-1.8	-1.6	-1.9	-0.4	-1.7	-0.9	0.7	-0.7	-0.8	-0.5	-1.2	-2.0	-0.4	-1.2	-1.5
Leg predicted mass (right)	1.1	5.9	12.2	2.8	2.3	2.6	1.3	0.6	-0.3	1.8	1.7	1.7	0.9	2.2	1.7	2.9	1.5	3.5	3.5	1.1	3.1	2.0	3.1	3.1	3.2	2.8	3.1	3.4
Heel T-Score	1.0	8.3	25.3	4.3	1.1	1.6	-1.6	5.0	3.7	0.6	-0.5	2.7	0.1	0.4	0.7	1.1	4.8	2.4	1.7	3.9	3.0	4.4	3.6	3.6	1.5	3.0	3.6	3.0
BMI	1.0	5.6	13.9	3.2	2.3	1.7	1.3	1.1	1.5	0.7	-0.6	1.4	0.5	0.9	-0.1	1.9	2.7	3.2	3.7	1.6	3.6	3.2	1.4	3.1	3.3	3.3	3.0	3.1
Hearing difficulty/problems: Yes	1.0	1.5	4.8	-0.6	-1.0	-0.7	0.4	-1.0	0.8	-1.4	-1.5	-1.5	-0.3	-1.3	-1.6	-1.8	-0.4	-1.5	-0.4	-0.1	-0.5	-0.6	-2.0	-1.6	-0.9	-0.6	-1.6	-2.2
Eye problems/disorders: Diabetes related eye disease	1.0	1.1	2.7	-1.1	-1.0	-1.2	0.5	-1.0	-0.1	-0.7	-0.8	-1.3	1.0	-1.2	-1.0	-0.8	-1.0	-1.6	-1.2	0.6	-0.7	-0.8	-1.1	-1.5	-1.6	-0.7	-1.5	-1.2
Leg fat-free mass (left)	1.0	5.2	12.2	2.7	2.1	2.3	1.1	0.6	-0.1	1.7	1.5	1.3	0.7	2.0	1.5	2.5	1.4	3.4	3.5	0.7	2.9	1.9	2.8	2.8	3.2	2.8	2.8	3.2
Heel bone mineral density (BMD) T-score, automated (right)	1.0	2.2	14.5	2.2	-0.6	-0.4	-0.8	3.8	1.3	-0.4	-1.5	0.6	-0.4	-1.0	-1.1	-1.6	3.1	0.5	0.5	2.1	1.7	2.1	1.1	0.5	-0.3	1.5	0.4	0.1
Ever unenthusiastic/disinterested for a whole week	1.0	1.2	5.5	1.8	-0.6	-0.2	1.0	2.3	1.1	-0.9	-0.8	0.1	-0.7	-0.8	-0.9	-0.3	2.4	0.6	0.5	0.9	1.1	1.2	1.5	0.4	-0.4	1.6	0.4	0.5
Arm fat-free mass (right)	1.0	5.0	13.7	2.9	1.7	2.0	0.6	1.7	-0.1	1.3	1.4	1.2	0.6	2.0	1.4	2.1	1.8	3.5	3.7	0.0	2.8	2.0	3.1	2.4	3.2	3.1	2.4	3.1
Illnesses of father: None of the above (group 1)	1.0	1.2	4.1	1.2	-0.0	1.1	-1.6	1.6	0.2	0.3	0.8	0.8	0.0	0.6	1.0	1.5	1.7	1.4	0.7	1.3	0.6	0.9	2.0	0.4	-0.1	1.7	0.4	1.2
Ever had prostate specific antigen (PSA) test	1.0	1.2	4.2	-0.9	-1.4	-1.3	0.4	-0.3	-0.5	-1.4	-0.8	-1.2	0.5	-1.2	-0.8	-1.1	-0.8	-1.0	-0.4	-2.0	-1.6	-0.9	-1.9	-1.3	-0.5	-0.4	-1.2	-1.1
Depression (Nagel 2018)	0.9	1.4	4.5	2.1	0.6	1.2	0.8	1.1	1.1	0.1	0.0	0.5	-1.2	0.6	0.2	0.6	1.8	1.8	1.3	0.4	1.2	1.9	1.3	1.0	1.4	1.6	1.0	1.2
Neuroticism (2016)	0.9	1.2	5.0	1.6	-0.4	-0.1	0.2	1.3	2.0	-0.5	-1.1	-0.4	0.1	-0.8	-1.0	-0.5	1.8	0.8	2.2	-0.2	1.7	1.0	0.4	0.4	0.5	2.2	0.4	0.6
Ulcerative Colitis	0.9	1.3	6.3	-1.2	-0.5	-0.5	-1.3	0.7	0.3	-0.8	0.2	-0.0	0.9	-0.2	-0.0	0.6	-0.6	-1.6	-1.0	-2.5	-1.3	-1.6	-1.2	-1.2	-0.5	-2.0	-1.2	-1.6
Blood Platelet Count	0.9	10.0	22.4	-4.7	-1.6	-1.9	-0.0	-3.9	-3.3	-1.1	0.3	-2.6	0.4	-1.0	-0.7	-1.4	-4.5	-3.9	-4.0	-3.4	-4.0	-3.9	-4.3	-3.8	-2.6	-4.6	-3.8	-3.8
Medication: Metformin	0.9	1.3	3.8	-1.9	-0.9	-1.0	-0.0	-1.0	-0.8	0.1	0.1	-1.4	0.4	-0.4	0.1	-0.5	-1.8	-1.2	-1.1	-1.8	-0.9	-1.9	-1.2	-1.3	-0.8	-1.4	-1.3	-1.1
Townsend deprivation index at recruitment	0.9	1.3	3.4	0.9	1.2	1.0	1.3	0.2	1.2	1.0	0.3	1.6	-0.6	1.0	0.5	0.7	0.6	1.3	1.8	0.5	1.8	0.9	1.1	1.3	1.3	1.2	1.3	1.7
Chronic bronchitis/emphysema (father)	0.9	1.1	3.8	-1.3	-1.1	-1.6	0.3	-0.8	-1.2	-0.7	-0.2	-1.4	-0.3	-0.8	-0.9	-0.3	-1.4	-1.0	-0.2	-2.0	-1.2	-1.5	-1.2	-1.2	-0.6	-0.4	-1.2	-0.8
Number of incorrect matches in round	0.9	1.6	5.2	1.2	-1.9	-1.1	-2.2	2.0	0.9	-1.3	-1.7	-0.8	-0.7	-1.9	-0.8	-1.0	2.3	0.4	0.2	0.8	-0.3	1.1	-0.0	-0.1	-0.8	1.9	-0.1	-0.1
Alcohol usually taken with meals	0.9	1.5	4.8	-1.0	-1.3	-1.6	-0.1	0.0	-0.6	-1.4	-1.1	-1.5	0.1	-1.4	-1.5	-0.6	-0.7	-1.7	-2.2	0.2	-1.2	-0.5	-1.6	-0.9	-1.6	-1.4	-0.9	-1.6
Noisy workplace	0.9	1.1	5.5	1.5	0.3	0.6	-1.8	1.8	1.0	-0.3	-0.6	0.2	-0.1	-0.1	0.2	-0.7	1.9	0.9	0.5	2.4	0.9	1.7	1.1	0.3	-0.0	1.5	0.2	0.8
Depression (self-reported)	0.9	1.0	4.2	2.1	0.5	1.3	0.8	0.9	0.3	-0.2	0.2	0.0	-0.7	0.2	-0.1	0.1	1.6	1.2	1.8	-0.3	1.9	0.7	1.3	0.5	1.3	1.4	0.5	0.1
Arm fat mass (right)	0.9	3.9	11.5	2.1	2.1	1.4	0.5	0.5	1.4	0.6	-0.2	1.0	0.5	1.0	0.1	1.9	1.5	2.5	3.4	1.6	3.2	2.1	1.5	2.6	2.6	2.8	2.6	3.0
Qualifications: O levels/GCSEs or equivalent	0.9	1.4	4.4	-1.3	-0.2	-0.2	1.8	-1.5	-1.7	0.5	0.9	-0.7	0.1	-0.1	0.4	-2.1	-1.6	-1.1	-1.2	-1.0	-1.3	-1.8	-0.9	-0.9	-0.7	-1.7	-0.9	-1.2
Qualifications: College or University degree	0.9	2.8	6.9	-0.8	-2.4	-1.9	-1.7	-0.1	-0.3	-1.9	-1.3	-1.7	-2.5	-2.3	-1.8	-2.1	-0.7	-2.3	-2.1	1.0	-1.3	-0.9	-0.4	-1.1	-2.6	-1.3	-1.1	-2.0
Mouth/teeth dental problems: Loose teeth	0.9	1.1	3.9	-0.2	1.0	0.7	1.7	-1.5	-0.4	1.0	0.0	2.0	-0.1	0.6	0.5	0.3	-0.6	0.5	-0.3	1.6	-0.5	1.0	0.4	1.8	1.0	-0.4	1.8	1.3
Emphysema/chronic bronchitis	0.9	1.0	4.0	-1.2	-0.7	-1.0	-0.2	-0.9	-1.2	-1.0	-0.8	-0.6	-1.6	-1.3	-1.0	-0.5	-0.6	-1.1	-1.3	-0.4	-0.5	-0.9	-0.9	-1.2	-2.0	-0.6	-1.2	-0.7
Leg fat mass (right)	0.9	3.3	10.9	2.0	1.9	1.1	0.2	0.9	1.4	0.5	-0.2	0.7	0.6	1.0	0.1	1.6	1.6	2.4	3.3	1.0	2.8	1.9	1.5	2.2	2.4	2.9	2.2	2.9
Back pain experienced in last month	0.9	1.2	7.0	0.7	-0.6	-0.6	-0.9	1.3	2.6	-1.5	-1.4	-1.1	-1.0	-0.7	-1.3	-1.3	1.1	0.6	1.6	-0.0	1.0	1.1	0.0	-0.5	0.4	1.8	-0.5	0.3
Asthma (self-reported)	0.9	1.8	10.9	-0.6	2.0	1.8	3.3	-2.7	-1.4	1.2	0.6	1.1	0.7	1.3	0.9	2.1	-1.3	0.4	0.3	0.4	0.7	0.1	-1.0	0.5	1.4	-0.9	0.5	0.1
Arm fat-free mass (left)	0.9	4.5	12.3	2.5	1.8	1.9	0.6	1.2	-0.1	1.1	1.2	1.2	0.4	1.9	1.4	2.2	1.7	3.4	3.5	0.2	2.8	1.9	2.8	2.4	3.0	2.9	2.4	3.1
Leg fat mass (left)	0.9	3.5	10.1	2.0	2.0	1.1	0.3	0.8	1.2	0.6	-0.2	0.8	0.7	1.0	0.2	1.8	1.6	2.4	3.2	1.2	2.9	2.0	1.7	2.4	2.4	2.9	2.4	3.1
HbA1C	0.8	0.9	2.3	-1.5	0.8	0.6	1.1	-1.0	-1.4	0.8	1.1	0.9	1.4	0.5	0.9	1.5	-0.5	-0.4	-1.4	0.0	-0.5	-0.8	-0.7	0.1	0.2	-1.5	0.1	-0.9
Schizophrenia (2014)	0.8	1.8	5.9	-1.5	-1.8	-1.7	-1.2	-0.2	-0.3	-0.4	-0.9	-1.2	-1.8	-1.2	-0.7	-1.7	-1.0	-1.4	-1.9	-1.0	-2.4	-0.5	-1.0	-1.3	-1.0	-1.5	-1.3	-1.4
Supplements: Zinc	0.8	0.9	3.3	-1.8	0.2	-0.7	-0.9	-1.4	-0.7	-0.0	0.5	0.1	-0.1	-0.3	-0.2	1.6	-1.7	-1.1	-0.9	-0.4	-0.8	-1.7	-0.4	-0.6	-1.4	-1.0	-0.6	0.1
Medication: Co-codamol	0.8	1.0	6.1	-1.1	0.5	0.3	1.1	-1.6	-2.5	1.0	0.5	-0.1	0.2	0.6	0.6	-0.3	-1.3	-0.7	-0.9	-1.0	-1.1	-1.2	-0.4	-0.6	0.0	-1.4	-0.6	-0.9
Bilateral oophorectomy (both ovaries removed)	0.8	0.9	3.8	1.1	0.7	0.4	-1.1	0.6	0.9	0.3	-0.4	1.4	-0.4	-0.3	-0.5	1.2	1.1	0.4	0.2	2.0	1.1	1.2	0.9	1.4	-0.0	0.6	1.4	0.8
Serious illness, injury or assault to yourself	0.8	1.0	2.7	-0.6	-1.2	-0.8	-0.2	-0.3	0.1	-1.3	-1.3	-0.8	-1.5	-1.2	-1.6	-0.3	-0.5	-1.3	-0.2	-0.3	-0.7	-0.4	-1.3	-1.3	-0.7	-0.7	-1.4	-1.6
Weight	0.8	3.7	10.5	2.0	2.1	1.5	0.8	0.4	0.6	0.9	0.8	1.0	0.6	1.4	0.7	2.2	1.1	2.7	3.2	1.0	2.9	1.7	1.9	2.6	2.6	2.6	2.6	3.1
Hip circumference	0.8	3.3	9.8	2.0	2.0	1.5	0.8	0.0	1.2	0.6	0.6	1.2	0.7	1.3	0.6	1.7	1.1	2.4	3.1	1.1	2.3	1.7	1.6	2.5	2.6	2.3	2.5	2.9
Frequency of tiredness / lethargy in last 2 weeks	0.8	1.2	3.4	0.9	1.3	1.0	1.1	-0.5	1.1	-0.2	0.1	1.0	-0.7	0.5	-0.1	1.6	0.6	1.3	1.3	1.1	1.1	1.8	-0.1	1.5	1.7	0.9	1.5	1.5
Pulse rate	0.8	1.3	3.0	0.9	1.5	1.7	0.7	0.1	0.5	0.1	1.0	1.7	-0.0	1.2	1.0	1.3	1.0	1.7	1.6	1.0	1.7	0.8	0.6	0.9	1.3	1.1	0.9	1.3
Asthma	0.8	1.6	10.0	-0.5	2.0	1.8	3.2	-2.3	-1.3	1.1	0.7	1.2	0.7	1.3	0.9	1.9	-1.1	0.5	0.2	0.4	0.7	0.2	-0.8	0.5	1.4	-0.8	0.5	0.3
Breastfed as a baby	0.8	1.0	3.6	1.3	-1.1	-0.5	0.3	1.9	1.5	-0.9	-1.2	-1.2	-0.6	-0.9	-1.1	-1.5	1.7	-0.0	0.2	0.2	-0.0	1.2	-0.1	-0.7	-0.4	0.9	-0.7	-0.4
Seen doctor (GP) for nerves, anxiety, tension or depression	0.8	1.2	3.6	1.5	0.6	0.5	1.6	0.6	1.8	-0.1	-0.4	0.9	0.6	-0.3	-0.5	-0.1	1.3	0.7	1.2	0.7	1.0	1.7	0.5	1.9	1.1	0.9	1.9	1.3
Exposure to tobacco smoke outside home	0.8	1.1	4.7	-1.0	1.0	0.6	2.2	-1.8	-0.5	1.2	1.2	0.8	0.9	0.6	0.3	1.4	-1.0	0.5	1.4	-1.3	1.3	-0.8	-0.9	0.1	0.7	0.2	0.1	0.8
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.8	0.9	2.2	-0.8	1.1	0.8	1.0	-1.4	-1.1	0.5	1.2	1.2	1.3	0.8	1.0	1.2	-1.1	-0.2	-0.9	-0.3	-1.4	-0.5	-0.5	0.8	0.4	-1.5	0.8	0.3
Arm fat percentage (left)	0.8	3.4	9.1	1.8	2.1	1.2	0.5	0.3	1.8	0.7	-0.3	1.2	1.0	0.7	-0.1	1.8	1.3	2.0	2.8	1.9	3.0	2.1	1.0	2.8	2.1	2.4	2.8	2.9
Whole body water mass	0.8	4.5	11.4	2.6	1.7	1.9	0.8	1.1	-0.2	1.2	1.4	1.1	0.3	1.9	1.4	2.3	1.5	3.3	3.4	0.2	2.6	1.9	3.0	2.4	3.0	2.8	2.4	3.0
Ever taken oral contraceptive pill	0.8	0.9	4.1	-0.5	1.6	1.3	1.4	-2.0	-0.2	0.9	1.3	0.4	0.3	1.5	1.7	0.7	-1.2	0.3	-0.0	0.5	0.0	-0.8	-0.4	-0.3	0.6	-0.6	-0.3	-0.1
Basal metabolic rate	0.8	4.2	11.1	2.5	1.8	1.8	0.8	1.0	0.0	1.1	1.3	1.1	0.3	1.8	1.2	2.2	1.4	3.2	3.3	0.5	2.8	1.8	2.8	2.4	2.9	2.7	2.4	3.0
Vascular/heart problems diagnosed by doctor	0.8	2.2	6.7	-0.9	-2.6	-2.3	-1.9	1.4	0.0	-1.3	-1.0	-1.5	-0.7	-1.7	-1.2	-0.6	-0.2	-2.0	-2.3	-0.9	-1.7	-1.0	-0.2	-1.1	-2.3	-1.5	-1.0	-1.1
Basal cell carcinoma (self-reported)	0.8	0.9	3.7	1.2	-0.5	-0.1	0.1	1.8	1.6	-1.3	-1.5	-0.4	-0.8	-0.6	-1.0	-1.2	1.9	0.1	-0.0	0.8	0.0	1.8	-0.3	0.1	0.1	0.3	0.0	-0.0
Arm predicted mass (left)	0.8	4.2	11.3	2.4	1.9	1.9	0.9	1.0	-0.2	1.1	1.4	1.1	0.3	2.0	1.5	2.0	1.4	3.2	3.4	0.2	2.7	1.7	2.7	2.2	3.0	2.7	2.2	2.9
Alzheimer’s Disease (in father)	0.7	0.7	2.3	1.3	0.1	0.1	0.7	1.0	1.0	-0.5	-0.6	0.6	-1.3	0.1	-0.1	-0.0	1.0	0.8	0.6	1.0	0.7	0.8	1.5	1.0	0.1	1.4	1.0	1.1
Lupus	0.7	1.1	3.1	-1.2	-1.2	-1.8	-1.0	0.5	-0.4	-1.4	-0.5	-1.2	0.2	-0.7	-1.2	-1.4	-0.7	-1.1	-1.1	-0.9	-1.0	-0.6	-0.8	-1.6	-1.0	-0.6	-1.6	-0.9
Triglycerides	0.7	1.1	3.1	0.0	1.1	1.2	0.8	-0.3	-0.6	1.6	1.5	1.7	1.2	1.6	1.4	0.7	-0.2	1.1	0.7	-0.1	0.9	-0.3	1.4	1.1	0.8	0.3	1.2	1.1
Blood Red Count	0.7	7.2	15.7	3.5	3.8	3.8	1.5	0.9	0.4	2.1	1.2	4.0	1.6	2.7	2.2	2.1	2.6	3.1	2.2	2.6	3.0	2.9	2.5	3.5	3.5	1.2	3.4	2.6
Chronotype (morning person)	0.7	1.6	4.4	-1.6	-0.6	-0.6	0.2	-0.7	-1.9	0.1	0.1	-1.1	-0.3	-0.5	0.0	-1.6	-1.1	-2.0	-1.6	-0.3	-1.0	-1.7	-0.7	-1.9	-1.5	-1.9	-1.9	-2.1
Frequency of depressed mood in last 2 weeks	0.7	1.0	4.1	1.2	0.5	0.8	1.5	0.4	0.9	0.6	0.6	0.6	-0.6	0.5	-0.1	0.6	1.0	1.5	2.0	-1.0	1.4	0.8	0.8	0.7	1.4	1.4	0.7	1.2
Severe depression (siblings)	0.7	0.7	2.7	0.7	0.5	1.2	1.0	-0.3	-0.3	0.9	0.9	0.7	0.6	1.1	1.2	-0.5	0.0	1.0	1.6	-0.7	0.5	0.2	0.8	1.0	1.5	0.4	1.0	0.7
Supplements: Glucosamine	0.7	0.9	3.0	-1.2	-0.6	-0.3	-0.3	-1.4	0.9	-0.5	0.4	-0.8	0.1	-0.5	-0.3	-0.2	-1.7	-1.0	-0.7	-0.4	-1.5	-1.3	-1.3	-1.2	-0.9	-1.0	-1.3	-0.8
Diverticular disease/diverticulitis (self-reported)	0.7	0.9	3.7	-0.7	-1.2	-1.9	-0.1	0.7	0.6	-1.0	-1.2	-0.8	-0.9	-1.5	-1.3	-0.1	-0.1	-1.0	-0.9	-1.4	-1.3	0.4	-0.8	-0.4	-0.6	-0.5	-0.3	-0.1
Medication: Ramipril	0.7	0.9	2.4	-1.0	-0.5	-0.9	0.0	-0.6	0.7	-0.8	-0.7	-1.2	-0.8	-1.1	-1.2	-1.1	-0.5	-0.9	-0.5	-0.8	-0.8	-0.4	-1.5	-1.5	-0.7	-0.6	-1.5	-1.4
Lung cancer (father)	0.7	0.8	2.5	-1.2	-0.9	-0.4	-1.4	-0.1	-1.3	-0.2	0.5	-0.5	-0.6	-0.4	0.6	0.8	-0.5	-0.5	-0.6	-0.9	-1.5	-1.3	-0.2	-1.5	-1.1	-0.5	-1.6	-0.5
Tense / ‘highly strung’	0.7	1.2	4.2	-0.1	1.1	0.7	0.5	-0.6	0.3	1.4	2.1	1.0	1.9	1.4	1.5	1.1	-1.0	0.9	0.4	-1.8	-0.9	-0.6	0.6	0.4	1.4	-0.5	0.5	1.1
Pulse wave reflection index	0.7	0.8	2.3	1.3	0.6	0.5	-0.4	0.9	0.6	0.4	-0.3	1.0	-0.5	0.5	-0.1	-0.0	1.0	1.2	1.2	0.2	1.2	0.9	1.3	1.2	0.9	1.5	1.2	1.1
Number of children fathered	0.7	0.8	2.5	-0.5	-1.2	-1.6	-0.4	0.6	0.1	-1.5	-1.5	-0.6	0.5	-1.3	-1.3	-1.4	-0.2	-1.0	0.1	-0.7	-0.6	-0.5	-0.5	-0.4	-0.7	0.1	-0.4	-0.6
Eye problems/disorders: None of the above	0.7	0.8	2.9	-0.6	0.3	0.6	-0.2	-0.2	-0.4	1.5	1.7	1.0	-1.2	0.9	1.2	1.4	-0.6	0.1	-0.1	0.1	0.4	-1.0	1.7	0.8	-0.2	-0.6	0.9	1.0
Whole body fat mass	0.7	3.1	9.1	1.8	1.9	1.1	0.4	0.4	1.3	0.6	-0.0	0.8	0.8	0.8	0.0	1.8	1.2	2.1	3.0	1.2	2.9	1.8	1.5	2.4	2.2	2.6	2.4	2.9
Illness, injury, bereavement, stress in last 2 years	0.7	0.9	7.2	-1.1	0.4	0.3	-0.7	-1.6	-2.7	1.0	0.5	0.4	-0.1	0.6	1.3	-0.4	-1.1	-0.2	-1.3	-0.5	-0.3	-1.1	-0.2	-0.6	-0.6	-0.6	-0.6	-0.7
Whole body fat-free mass	0.7	4.2	10.2	2.5	1.7	1.9	0.8	1.0	-0.3	1.3	1.5	1.1	0.4	1.9	1.5	2.1	1.3	3.2	3.2	0.2	2.5	1.7	2.9	2.3	2.9	2.6	2.3	2.9
Handedness (chirality/laterality): Left-handed	0.7	0.9	5.0	-1.4	0.2	0.1	-0.2	-0.9	-2.2	0.3	0.7	0.4	-1.2	0.4	0.5	-0.6	-1.2	-0.7	-1.6	1.0	-0.9	-0.4	-0.5	-0.7	-0.7	-1.4	-0.8	-0.7
Osteoporosis (self-reported)	0.7	0.9	4.1	-1.6	-0.1	-0.9	-0.2	-0.9	0.7	-0.4	-0.7	0.0	0.1	-0.9	-0.9	0.4	-1.1	-1.3	-1.3	-1.1	-1.2	0.0	-1.7	0.0	-0.6	-2.0	0.1	-0.6
Medication: Blood pressure	0.7	1.3	6.6	-1.9	0.6	-0.3	1.0	-2.6	-1.6	0.1	-0.1	-0.2	1.1	0.4	-0.4	-0.8	-2.2	-0.3	-0.0	-1.9	-0.5	-1.1	-2.3	-0.1	0.8	-0.9	-0.1	-0.6
Ever smoked	0.7	1.2	3.8	-0.6	-1.6	-1.5	-0.4	0.3	1.3	-1.3	-1.0	-2.0	-1.1	-1.7	-1.6	-0.7	-0.4	-1.2	-0.7	0.2	-0.5	-0.7	-0.6	-1.1	-1.6	-0.3	-1.2	-1.0
Cholesterol lowering medication	0.7	1.1	4.3	0.6	1.5	1.1	0.1	-0.6	0.8	0.3	-0.6	0.8	-0.0	0.6	-0.2	0.4	0.1	0.5	0.5	2.1	1.1	1.5	0.3	2.0	0.6	0.5	2.1	1.5
Bipolar Disorder or Schizophrenia	0.6	1.5	4.0	-1.3	-1.9	-1.9	-1.2	0.1	-0.1	-0.4	-0.9	-1.2	-1.2	-1.3	-0.8	-1.8	-0.7	-1.2	-1.3	-1.1	-2.0	-0.5	-1.2	-1.4	-1.0	-0.9	-1.4	-1.2
Intelligence (Savage-Jansen 2018)	0.6	1.9	8.6	-0.4	2.0	1.7	2.6	-2.9	-1.3	1.6	1.2	1.3	1.1	1.2	1.3	0.3	-1.5	0.0	0.1	0.0	0.3	-0.5	-0.5	1.9	1.2	-1.4	2.0	0.6
Respiratory disease	0.6	1.4	7.3	-1.0	1.6	1.4	2.7	-2.6	-1.2	1.1	0.5	1.2	-0.6	1.1	0.6	1.8	-1.5	0.2	-0.0	0.1	0.4	-0.3	-0.7	0.4	0.8	-1.0	0.4	0.2
Type 2 Diabetes (T2D) (2018)	0.6	1.0	4.3	-1.0	-1.2	-1.0	-0.5	-0.8	0.1	0.1	-0.8	-2.0	0.1	-1.2	-0.2	-0.5	-0.7	-1.1	-1.1	-1.1	-1.1	-0.5	-2.1	-1.1	-0.7	-0.9	-1.0	-1.3
Angina	0.6	0.7	2.9	1.3	0.2	-0.1	-0.2	1.7	1.0	-0.7	-1.1	0.4	0.2	-0.8	-0.6	0.7	1.6	-0.1	0.5	1.0	1.2	1.3	1.0	0.4	-0.2	0.7	0.4	0.1
Vitamin and mineral supplements	0.6	0.8	3.3	1.8	0.5	0.9	0.2	1.2	0.5	0.6	-0.1	0.9	-0.7	0.5	0.4	-0.2	1.6	0.4	-0.1	1.4	0.2	1.4	1.4	1.3	0.5	-0.0	1.3	0.4
Age when periods started (menarche)	0.6	1.5	5.9	2.0	-0.8	-0.1	-1.5	2.3	1.7	-0.9	-1.1	0.4	-1.6	-0.9	-0.9	0.0	2.4	0.5	1.2	1.1	0.5	1.1	1.3	0.4	-0.0	1.9	0.3	0.2
Stomach or abdominal pain in last month	0.6	0.8	2.7	0.5	1.0	0.8	0.6	0.0	0.5	0.8	1.0	0.8	0.6	1.2	0.7	0.8	0.1	1.1	1.5	-0.5	1.1	0.4	1.2	0.6	1.0	1.0	0.7	1.6
Trunk fat mass	0.6	2.5	7.5	1.6	1.8	1.1	0.7	0.1	1.0	0.8	0.1	0.7	1.0	0.7	0.1	1.6	0.8	1.8	2.7	1.2	2.7	1.4	1.3	2.2	1.8	2.2	2.2	2.7
Financial difficulties in last 2 years	0.6	0.9	2.6	-0.5	-0.9	-0.7	0.8	-0.1	1.2	-1.0	-1.0	-1.3	-0.7	-1.0	-1.6	-0.5	-0.1	-0.8	0.1	0.0	-0.4	-0.1	-1.6	-1.4	-0.5	-0.4	-1.5	-1.4
Pain all over the body in last month	0.6	0.6	2.6	-1.1	-0.5	-0.9	1.4	-1.0	-0.7	-0.4	-0.5	-0.6	-0.5	-0.5	-0.2	-0.6	-1.3	-0.4	-0.7	-1.6	-0.5	-0.3	-1.2	-0.5	0.3	-0.7	-0.4	-0.7
Fluid intelligence score	0.6	1.3	6.2	-0.7	0.7	0.9	-0.2	-2.5	-2.4	1.1	1.9	0.1	1.8	0.5	1.2	0.8	-1.4	-0.5	-0.5	-0.5	-0.3	-1.7	-0.2	-0.0	-0.1	-1.6	-0.0	-0.8
Arm fat percentage (right)	0.6	2.5	7.3	1.4	1.9	1.0	0.4	0.0	1.9	0.4	-0.6	1.0	0.5	0.4	-0.3	1.6	1.2	1.6	2.4	1.7	2.7	1.8	0.7	2.3	1.7	2.0	2.3	2.5
Father’s age at death	0.6	0.8	3.6	-0.3	-1.1	-1.1	0.3	-0.4	0.3	-1.3	-0.8	-0.7	-1.2	-0.7	-0.7	0.2	-0.8	-1.3	-0.8	-0.8	-1.9	-0.3	-0.9	-0.2	0.1	-1.3	-0.1	-1.1
Worry too long after embarrassment	0.6	0.9	3.1	-0.0	0.6	0.7	1.4	-0.9	0.8	1.8	1.1	0.5	1.5	1.4	1.1	-0.4	-0.6	1.0	1.4	-0.9	0.4	-0.3	0.6	0.7	1.3	0.7	0.8	1.0
Seen a psychiatrist for nerves, anxiety, tension or depression	0.6	0.7	4.1	0.8	-0.7	-0.4	0.7	0.5	2.0	-1.1	-1.2	-0.8	-0.5	-1.4	-1.5	-0.5	1.1	-0.2	0.2	-0.2	0.3	0.9	-0.9	-0.4	-0.1	0.6	-0.4	-0.6
Wheeze or whistling in the chest in last year	0.6	1.1	3.4	0.6	1.5	1.1	0.8	-0.4	-0.2	0.5	0.1	1.0	-0.4	1.0	0.5	1.8	0.1	1.3	1.3	0.5	1.5	1.1	0.7	1.4	1.5	0.9	1.5	1.6
Health satisfaction	0.6	0.8	3.9	0.6	1.5	1.6	0.5	-1.0	0.9	0.0	0.6	1.2	0.5	0.6	0.5	2.0	0.3	0.6	0.9	1.1	1.0	0.4	0.2	0.7	0.6	0.3	0.6	0.6
Medication for pain relief, constipation, heartburn	0.6	1.0	4.2	1.5	0.1	0.1	0.1	1.9	1.6	0.2	-0.2	1.0	0.9	0.1	0.2	0.4	1.4	0.7	-0.1	1.2	0.3	2.0	1.0	1.2	0.9	0.4	1.2	1.1
Migraine (self-reported)	0.6	0.7	3.8	-0.7	-0.9	-1.0	-1.4	-0.6	0.3	-0.5	-0.7	-1.1	1.2	-0.7	-1.1	-0.2	-0.5	-0.0	0.6	-2.0	-0.6	-0.6	-1.4	-0.3	0.1	0.5	-0.3	-0.1
Pulse rate, automated reading	0.6	1.9	6.3	1.6	1.3	1.6	0.2	0.8	0.8	-0.3	0.3	1.1	0.4	1.3	0.8	0.7	1.4	2.1	2.5	1.3	1.7	1.6	0.7	1.6	2.2	1.8	1.6	1.6
Had major operations	0.6	0.7	4.1	-0.1	-1.1	-0.9	-2.0	0.9	0.3	-0.7	-0.6	-0.6	-1.2	-0.9	-0.7	0.4	0.3	-0.3	-0.5	0.0	-0.8	0.1	-0.2	-1.0	-1.2	0.2	-1.0	-0.5
Family relationship satisfaction	0.6	0.7	3.5	1.6	0.2	0.7	0.2	1.3	1.3	-0.0	-0.1	-0.4	0.7	0.3	-0.1	0.1	1.9	0.8	1.3	0.1	1.1	0.8	0.6	-0.3	0.4	1.3	-0.4	0.0
Average weekly red wine intake	0.6	0.9	2.4	-0.3	-1.0	-0.8	-0.4	0.0	-0.6	-1.0	-0.9	-1.0	-0.5	-1.1	-1.0	-1.4	-0.1	-1.2	-1.0	1.2	-0.9	-0.3	-1.0	-0.9	-1.5	-0.7	-1.0	-1.2
Miserableness	0.6	1.1	4.3	1.0	1.0	0.9	1.3	-0.4	0.9	0.4	0.0	0.5	0.4	1.0	-0.2	0.6	1.0	1.7	2.1	-0.8	1.2	0.9	-0.0	0.6	1.9	1.6	0.6	1.0
High cholesterol (Self-reported)	0.6	1.1	4.2	1.1	0.8	0.8	0.6	0.1	2.1	0.2	-0.4	0.3	0.6	0.5	0.2	-0.1	1.1	1.1	1.4	0.1	1.6	1.0	0.5	1.8	1.0	1.3	1.8	1.6
Medication: Atorvastatin	0.6	0.7	2.0	0.6	-1.0	-0.7	-0.6	0.9	0.3	-1.3	-1.4	-1.1	-0.1	-1.4	-1.2	0.2	1.0	-0.5	-0.5	0.7	-0.3	0.9	-0.3	-0.7	-0.8	0.1	-0.7	-0.9
Illnesses of father: High blood pressure	0.6	0.8	4.1	-0.3	1.2	0.8	2.0	-1.2	0.3	1.5	0.8	0.0	1.6	0.7	0.2	-1.0	-1.0	0.3	0.7	-0.4	0.4	-0.7	-0.6	-0.4	0.8	-0.3	-0.4	-0.3
Leg fat percentage (left)	0.6	2.0	6.5	1.3	1.8	0.6	0.3	0.2	1.1	0.3	-0.5	0.6	1.2	0.5	-0.3	0.9	1.1	1.5	2.5	1.2	2.5	1.5	0.8	1.9	1.7	2.1	1.9	2.4
Unable to work because of sickness or disability	0.6	0.8	3.6	0.2	1.2	0.7	1.1	-0.5	-0.3	-0.2	-0.0	1.3	-1.9	0.4	0.4	1.5	0.1	0.3	0.4	0.4	1.2	1.0	0.1	1.5	1.1	-0.1	1.5	0.5
Bipolar Disorder (2018)	0.5	0.7	2.6	1.5	-0.5	-0.4	-0.7	1.6	1.5	-0.6	-0.4	0.1	-0.2	-0.5	-0.2	0.1	1.4	0.5	1.5	0.5	1.2	0.8	0.6	0.1	0.2	1.4	0.1	0.6
Alzheimer’s Disease (including proxy)	0.5	0.8	2.6	0.4	-1.0	-0.9	-1.3	1.6	1.2	-1.2	-0.6	-0.5	-1.3	-0.3	-0.2	-0.6	0.3	-0.1	-0.0	1.6	-0.6	0.2	1.5	0.1	-1.0	0.9	0.1	1.0
Body Mass Index (BMI) (2010)	0.5	0.7	2.9	-0.0	1.2	1.4	1.1	-0.9	-0.1	1.7	0.8	0.6	0.4	1.1	1.2	0.4	-0.2	0.9	1.0	-0.3	0.7	-0.3	-0.0	0.6	1.0	0.4	0.6	0.4
Mean Putamen Volume	0.5	0.6	3.7	0.7	0.2	0.6	0.8	-0.4	1.9	0.1	-0.1	0.9	0.1	-0.1	0.1	-0.1	0.3	0.6	1.5	0.7	1.1	0.6	0.1	1.1	0.9	0.7	1.1	0.9
Cardiovascular Disease	0.5	1.8	6.1	0.4	2.5	2.1	2.1	-2.1	-0.2	1.1	0.9	1.0	1.0	1.6	1.2	1.1	-0.4	1.6	1.6	0.5	1.1	0.5	-0.1	1.3	2.0	0.6	1.3	1.4
Hand grip strength (left)	0.5	1.4	9.9	-0.6	1.0	1.1	0.6	-1.0	-3.1	1.1	1.9	0.9	1.1	1.7	1.8	1.0	-1.0	0.5	-0.9	-0.6	-0.7	-0.7	0.7	0.4	0.5	-1.4	0.4	0.2
Average weekly spirits intake	0.5	0.6	1.9	1.0	0.3	0.6	-1.3	0.9	0.5	0.6	0.2	-0.7	0.8	-0.1	0.2	0.8	1.0	0.9	1.4	-0.2	1.2	0.5	0.2	-0.8	0.5	1.3	-0.8	-0.0
Systolic blood pressure, automated reading	0.5	1.3	7.6	-1.7	0.1	-0.0	1.5	-2.8	-1.8	0.1	0.0	-0.5	0.5	-0.1	-0.4	-1.2	-1.7	-0.7	0.4	-0.1	0.1	-1.6	-1.8	-1.3	-0.3	-0.5	-1.4	-1.2
Hand grip strength (right)	0.5	1.2	6.8	-1.4	0.3	0.2	0.8	-1.7	-2.6	0.6	1.3	0.2	0.7	1.1	1.1	0.2	-1.7	-0.0	-0.6	-2.3	-0.8	-1.5	-0.4	-0.0	0.2	-1.3	0.0	0.0
Average weekly fortified wine intake	0.5	0.6	4.5	0.3	-0.3	-0.3	0.3	-0.4	-0.2	-0.9	-1.1	0.1	-2.1	-1.0	-1.3	-0.2	0.2	-0.4	-0.1	1.6	0.7	1.1	0.3	0.4	-0.3	0.2	0.4	-0.2
High blood pressure	0.5	1.4	4.1	0.6	2.0	1.7	1.9	-1.7	-0.1	0.8	0.3	0.9	0.7	1.0	0.6	-0.0	0.1	1.7	1.9	0.7	1.2	0.8	-0.4	0.8	1.9	1.5	0.8	0.8
Multivitamins +/- minerals	0.5	0.6	2.1	-1.5	-0.4	-0.4	-0.1	-0.9	-0.5	-0.3	0.4	-1.1	0.1	-0.2	-0.0	0.7	-1.3	-0.4	0.3	-0.9	0.2	-1.4	-1.0	-1.3	-0.5	-0.2	-1.3	-0.6
Medication: Levothyroxine sodium	0.5	0.9	2.5	-1.4	0.0	0.7	-0.3	-1.3	-1.2	1.0	0.7	0.4	-0.4	0.4	1.6	-0.5	-1.3	-0.9	-1.1	0.8	-0.4	-1.1	-0.6	-0.4	-0.7	-1.5	-0.4	-1.3
Sitting height	0.5	3.6	17.1	2.8	-0.8	-0.4	-1.6	4.1	0.7	-0.8	-0.5	-0.3	-2.7	-0.3	-0.4	0.3	2.9	1.5	1.0	1.6	1.8	2.1	3.9	1.3	-0.4	2.4	1.3	2.4
Hearing difficulty/problems with background noise	0.5	0.8	4.9	0.7	0.0	0.2	0.2	0.1	2.2	-1.1	-1.6	-0.2	-0.0	-0.5	-1.6	-0.6	0.9	0.2	1.1	0.2	1.0	1.4	-0.8	0.3	0.6	1.1	0.3	0.0
Mouth/teeth dental problems	0.5	0.8	4.7	0.9	-1.5	-0.7	-1.0	0.8	0.1	-2.2	-1.1	-1.2	0.1	-1.2	-0.7	-1.2	1.3	-0.5	-0.2	0.6	-0.2	0.5	-0.3	-0.1	-1.1	0.6	-0.1	-0.4
Mouth/teeth dental problems: Dentures	0.5	0.8	2.9	-0.2	-1.2	-1.2	-0.9	0.8	1.3	-1.4	-1.7	-0.9	-1.7	-1.6	-1.4	-0.1	0.4	-0.4	-0.0	-0.3	-0.0	0.2	-0.6	-0.5	-0.5	0.5	-0.5	-0.5
Gout (self-reported)	0.5	0.7	2.7	-0.6	-0.7	-0.7	-0.8	0.2	-0.3	-1.6	-1.0	-0.5	-0.8	-1.0	-0.6	-0.3	-0.0	-1.1	-1.6	0.6	-1.0	0.1	-1.1	0.6	-1.1	-1.0	0.6	-0.6
Body fat percentage	0.5	1.9	6.1	1.0	1.9	0.8	0.4	-0.3	1.2	0.7	-0.1	0.7	1.2	0.6	-0.0	1.4	0.5	1.4	2.3	1.2	2.4	1.2	0.6	2.0	1.6	1.8	2.0	2.5
Leg fat percentage (right)	0.5	1.8	7.1	1.3	1.5	0.4	0.1	0.4	1.6	0.1	-0.7	0.2	0.8	0.3	-0.5	0.6	1.1	1.4	2.7	0.8	2.4	1.4	0.6	1.5	1.7	2.3	1.5	2.2
Shortness of breath walking on level ground	0.5	0.6	2.4	0.5	-0.7	-0.2	0.1	-0.0	-0.4	-0.6	-0.9	-0.8	-1.5	-0.9	-0.7	-1.4	0.8	-0.3	-0.7	1.5	0.0	0.4	-0.4	-0.2	-1.1	0.2	-0.2	-0.4
Angina (self-reported)	0.5	0.6	2.6	1.2	0.3	0.1	-0.2	1.5	0.6	-0.7	-1.0	0.6	-0.1	-0.9	-0.5	0.8	1.6	-0.2	0.4	1.0	1.1	1.2	1.0	0.3	-0.3	0.5	0.3	-0.1
Medication: Seretide 50 evohaler	0.5	0.5	2.3	-0.7	1.0	0.4	-0.0	-1.3	-1.5	0.5	0.2	0.6	0.1	0.3	-0.1	1.5	-1.0	-0.4	-1.2	0.7	-0.4	0.1	-0.2	0.2	-0.2	-1.2	0.2	-0.0
Overall health rating	0.5	1.1	7.3	-1.5	1.1	0.2	1.2	-2.7	-0.4	-0.5	-0.2	0.3	-0.7	0.1	-0.7	1.1	-1.9	-0.4	0.4	-1.5	0.2	-0.9	-1.9	0.1	0.6	-0.7	0.1	-0.2
Smoking status: Previous	0.5	0.8	2.9	-0.4	-1.4	-1.3	0.2	-0.2	0.9	-1.1	-1.1	-1.7	-0.6	-1.3	-1.3	-1.2	-0.3	-0.2	0.7	-1.4	-0.3	-0.5	-0.9	-0.4	-0.4	0.7	-0.4	0.1
Mood swings	0.5	0.9	3.7	0.4	0.7	0.4	0.2	0.6	0.9	0.5	0.9	0.5	0.8	1.3	0.5	1.0	0.3	1.5	1.6	-1.1	0.8	0.4	0.9	0.7	1.3	1.3	0.8	1.9
Medication for cholesterol	0.5	0.8	4.8	1.6	-0.1	0.5	-0.8	1.4	1.1	0.0	0.5	0.4	-0.2	0.2	0.8	0.9	1.5	0.8	0.6	0.8	0.5	0.7	2.2	0.2	0.1	1.2	0.2	0.8
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.5	1.0	4.7	1.7	0.2	1.3	-1.9	1.5	0.8	0.2	-0.0	1.2	0.6	0.1	0.9	-0.6	2.2	0.4	0.4	1.4	0.7	1.1	1.3	0.8	0.0	0.5	0.8	0.1
Number of self-reported non-cancer illnesses	0.5	0.9	5.1	0.4	1.7	1.3	0.8	-1.0	2.2	-0.1	-0.2	0.6	0.2	0.2	0.2	1.9	0.3	0.7	1.0	0.0	1.1	0.7	-0.9	1.0	1.1	0.5	1.0	0.5
Wears glasses or contact lenses	0.5	0.6	2.4	-0.5	-0.8	-1.1	0.1	0.1	0.7	-0.8	-0.8	-0.7	-0.9	-1.2	-0.8	0.1	-0.2	-0.8	-1.6	0.5	-1.3	0.5	-0.5	-0.5	-1.0	-0.5	-0.5	-0.5
Hearing aid user	0.5	0.6	2.1	-0.5	-0.8	-0.3	-0.5	-0.4	0.3	-1.2	-0.8	-1.1	-0.9	-0.5	-0.9	-1.2	-0.1	-0.9	-0.5	-1.5	-0.2	-0.4	-0.9	-0.7	-0.4	-0.6	-0.7	-1.2
Pain type(s) experienced in last month: Hip pain	0.5	0.6	2.3	-0.5	-0.9	-0.9	-1.2	-0.2	1.3	-1.5	-1.2	-0.4	-1.1	-0.9	-1.2	-0.2	-0.1	-0.3	0.3	-1.4	0.0	0.1	-0.8	0.6	-0.0	0.1	0.7	0.3
Medication: Bendroflumethiazide	0.5	0.8	2.9	-1.0	0.6	0.7	1.1	-1.7	-1.4	0.8	0.6	0.2	-0.4	0.7	0.5	-0.8	-1.0	0.3	-0.1	-1.4	-0.6	-0.8	-1.5	-0.6	0.8	-0.6	-0.6	-0.8
Alcohol drinker status: Never	0.5	0.6	2.4	-0.8	0.2	-0.3	0.4	-0.9	-1.0	-0.6	-0.7	-0.1	0.3	-0.3	-0.6	0.7	-0.3	-0.8	-1.1	-0.7	-0.8	-0.0	-1.6	-0.7	-0.1	-1.3	-0.7	-1.3
Age started oral contraceptive pill	0.5	0.6	2.6	-0.2	-0.6	-0.0	0.1	-0.5	1.4	-0.5	-0.8	-0.9	-0.4	-0.5	-0.7	-1.1	-0.2	-0.7	-0.2	-0.5	-0.9	-0.3	-1.4	-1.1	-0.3	-0.1	-1.1	-1.6
Ever depressed for a whole week	0.5	0.6	5.0	0.7	-0.8	-0.1	2.2	0.8	0.1	-0.0	0.4	-0.6	-1.2	0.0	-0.1	-1.1	0.7	0.4	0.3	0.1	0.2	-0.5	1.6	-0.3	-0.7	0.9	-0.4	0.1
Pack years of smoking	0.5	0.7	3.1	-0.3	-0.8	-0.4	-0.2	-0.1	0.7	0.2	-0.4	-1.8	-0.1	-0.7	-0.7	-1.2	-0.1	-1.2	-1.0	-0.0	-0.9	-0.4	-1.0	-1.0	-1.2	-0.8	-1.0	-1.3
Alzheimer’s Disease (in mother)	0.4	0.5	3.0	-0.3	-0.6	-1.0	-1.7	1.1	1.3	-1.1	-0.4	-0.3	-1.2	-0.4	-0.5	0.0	-0.2	-0.4	0.0	0.7	-0.1	-0.0	0.6	-0.1	-0.6	0.2	-0.1	0.8
Verbal and Numeric Reasoning (VNR)	0.4	1.0	7.3	-0.3	0.9	1.1	1.1	-2.7	-2.3	0.9	1.0	0.3	1.0	0.5	0.9	0.0	-1.2	-0.5	-0.3	-0.1	-0.2	-0.9	-0.4	0.5	0.2	-1.4	0.5	-0.5
LDL Cholesterol	0.4	0.6	2.3	0.9	-0.3	-0.4	-1.0	1.5	0.9	-0.9	-0.8	0.9	-0.3	-0.6	-0.4	-0.3	1.2	-0.1	-0.6	1.5	-0.0	1.2	0.8	0.7	-0.4	0.3	0.7	0.4
Blood White Count	0.4	2.7	6.2	0.3	-1.8	-2.1	-2.5	2.1	1.1	-2.2	-1.7	-2.2	-1.7	-2.0	-1.5	-0.7	1.3	-0.8	-1.4	-1.5	-1.9	0.6	-1.5	-2.2	-1.0	-0.3	-2.2	-1.6
Other serious medical condition/disability diagnosed by doctor	0.4	0.5	3.0	0.2	1.0	0.8	-0.5	-0.4	1.2	0.2	0.2	0.8	0.2	0.1	-0.2	1.7	0.2	-0.2	0.2	1.6	0.2	1.0	-0.1	0.7	0.2	-0.5	0.7	0.2
Ever had hysterectomy (womb removed)	0.4	0.5	1.3	-0.8	-0.4	-1.0	1.0	-0.7	0.4	-1.1	-0.6	0.3	-0.6	-0.7	-1.0	0.8	-0.6	-0.7	-0.6	-0.5	-0.7	-0.4	-0.9	-0.5	-0.7	-0.4	-0.5	-0.6
Trunk fat percentage	0.4	1.8	5.9	1.0	1.8	0.8	0.8	-0.4	1.2	0.7	-0.1	0.7	1.2	0.4	-0.2	1.3	0.4	1.2	2.2	1.3	2.4	1.1	0.6	1.9	1.4	1.7	2.0	2.4
Hayfever, allergic rhinitis or eczema	0.4	0.8	3.4	0.1	-0.3	-0.7	0.8	-0.2	0.8	-1.5	-1.8	-0.7	-0.6	-1.2	-1.6	-0.0	0.6	0.1	1.1	-0.9	-0.1	0.8	-1.8	-0.2	0.8	0.8	-0.3	-0.2
Medication: Atenolol	0.4	0.5	2.2	-0.5	0.5	0.3	0.6	-1.2	-1.0	1.2	0.3	-0.0	0.7	0.7	0.6	0.5	-0.6	0.5	0.8	-1.5	0.2	-0.9	-1.1	-0.3	0.7	0.2	-0.3	-0.1
High blood pressure (mother)	0.4	0.6	1.6	-1.2	1.0	0.6	0.5	-1.2	-0.9	0.6	0.7	0.5	0.1	1.0	0.7	-0.3	-1.2	0.1	-0.6	-1.0	-0.8	-0.3	-1.0	-0.4	0.6	-1.3	-0.5	-0.1
Past tobacco smoking	0.4	0.7	2.4	0.6	1.2	1.2	-0.2	0.2	-1.1	0.8	0.9	1.5	1.1	1.2	1.3	1.1	0.5	0.5	-0.2	0.6	0.3	0.6	0.9	0.7	0.7	-0.2	0.7	0.4
Forced vital capacity (FVC)	0.4	1.5	7.5	-0.6	0.8	1.5	-0.1	-1.8	-2.7	1.9	2.0	0.1	0.5	1.6	2.0	1.0	-1.4	0.2	-0.4	-0.7	-0.4	-1.7	0.6	0.0	-0.0	-1.2	0.0	0.1
Hayfever/allergic rhinitis (self-reported)	0.4	0.5	1.6	-1.3	-0.1	-0.2	0.6	-0.9	-0.8	-0.2	-0.3	-0.3	-0.6	-0.6	0.1	-0.2	-0.7	-1.1	-0.9	-0.1	-0.8	-0.4	-1.0	-0.9	-0.5	-1.0	-1.0	-1.2
Trunk fat-free mass	0.4	2.4	6.7	1.9	1.0	1.3	0.4	1.1	-0.5	0.6	1.2	0.5	-0.2	1.5	1.1	1.6	1.1	2.6	2.6	-0.3	1.8	1.4	2.4	1.5	2.4	2.0	1.5	2.2
Falls in the last year	0.4	0.5	2.8	0.6	-0.3	-0.5	-0.2	0.5	0.9	-0.8	-1.1	0.1	-1.7	-1.0	-1.5	-0.4	1.1	-0.4	0.1	0.3	0.3	1.1	0.2	0.2	-0.3	0.2	0.2	0.1
Number of live births	0.4	0.6	2.8	-1.0	-0.1	-0.3	0.2	-1.7	0.4	-0.0	-0.1	0.2	0.1	-0.5	0.2	-0.8	-1.0	-0.8	-1.0	-0.6	-1.2	-0.7	-1.4	0.0	-0.6	-1.1	0.1	-0.6
Medication: Lansoprazole	0.4	0.4	1.4	0.9	0.8	0.9	0.5	0.8	1.2	0.0	-0.0	0.7	0.8	0.4	0.2	-0.3	0.9	0.4	0.6	0.1	0.5	1.0	0.4	0.6	0.7	0.2	0.6	0.6
Trunk predicted mass	0.4	2.4	6.5	1.9	0.9	1.2	0.3	1.2	-0.5	0.5	1.1	0.5	-0.3	1.4	1.0	1.5	1.1	2.5	2.5	-0.4	1.8	1.4	2.5	1.5	2.3	2.0	1.5	2.2
Length of working week for main job	0.4	0.5	1.2	-0.3	-1.0	-0.5	-1.0	-0.0	-1.0	-0.7	-0.1	-1.1	-0.7	-0.6	0.2	0.2	0.0	-0.3	-1.0	0.8	-0.7	-0.1	-0.9	-0.8	-0.9	-0.2	-0.8	-0.8
Medication for cholesterol, blood pressure or diabetes	0.4	0.7	3.6	0.4	0.3	0.4	0.2	0.4	-0.8	0.9	0.8	1.2	-0.1	0.9	0.6	0.8	0.2	0.9	0.1	0.2	0.4	0.4	1.2	1.8	0.6	0.3	1.9	1.4
Medication: Amlodipine	0.4	0.5	2.6	-0.9	0.3	-0.0	1.1	-1.0	0.4	0.3	-0.1	-1.0	0.3	-0.0	-0.3	-1.1	-1.0	-0.2	0.2	-0.4	-0.4	-0.4	-1.6	-0.9	0.3	-0.0	-0.9	-0.7
Suffer from ‘nerves’	0.4	0.6	3.3	0.6	1.2	0.7	0.2	-0.5	0.4	0.3	0.6	0.9	0.3	0.8	0.3	1.2	0.2	0.9	1.2	-1.2	0.2	0.6	0.3	0.6	1.8	0.5	0.6	0.6
Hypertension (Self-reported)	0.4	1.2	3.7	0.3	1.9	1.5	1.7	-1.9	-0.0	0.8	0.4	0.8	0.7	1.1	0.6	0.3	-0.2	1.5	1.9	0.4	0.9	0.5	-0.5	0.6	1.8	1.2	0.5	0.6
Long-standing illness, disability or infirmity	0.4	0.6	2.6	-1.3	0.0	-0.3	0.4	-1.5	0.1	-0.6	-0.4	-0.4	-0.4	-0.5	-0.8	0.7	-1.4	-0.6	0.1	-1.3	-0.4	-0.9	-1.6	-0.2	-0.2	-0.5	-0.2	-0.5
Eye problems/disorders: Cataract	0.4	0.4	2.5	0.9	0.6	0.7	1.0	-0.0	0.4	-0.6	-0.9	-0.4	1.6	-0.1	-0.4	-0.0	0.6	-0.1	0.4	0.4	0.7	0.7	-1.1	-0.3	0.3	0.1	-0.3	-1.0
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.4	0.5	2.1	0.5	-0.7	-0.5	1.1	0.7	1.0	-0.7	-0.7	-0.7	0.1	-0.5	-0.8	-1.5	0.6	0.5	1.3	0.1	0.3	0.5	-0.6	-0.2	0.4	1.3	-0.2	0.0
Guilty feelings	0.4	0.6	5.9	1.0	0.5	0.5	-1.0	0.7	2.4	-0.7	-0.3	-0.0	0.1	0.1	-0.1	0.3	1.0	0.6	1.0	-1.2	0.3	0.9	-0.0	-0.4	0.8	0.8	-0.4	-0.2
Medication: Paracetamol	0.4	0.6	3.3	-1.0	0.6	0.4	1.1	-1.8	-0.9	0.4	0.7	0.0	1.0	0.8	0.5	0.4	-1.7	-0.2	0.5	-0.2	-0.2	-0.9	-0.6	0.0	0.4	-0.4	0.0	0.2
Medication: Lisinopril	0.4	0.5	2.2	0.9	0.2	-0.1	-0.0	0.5	0.6	-0.9	-1.2	0.1	-1.5	-0.5	-1.0	1.2	0.8	0.1	0.0	0.8	0.4	1.4	0.1	0.5	0.4	0.1	0.5	-0.0
Number of operations (self-reported)	0.4	0.5	2.0	-0.8	-0.4	-0.7	-0.9	0.5	0.9	-0.3	0.3	-0.1	-0.2	-0.5	-0.5	0.2	-0.4	-1.0	-0.8	-0.6	-1.0	-0.9	0.0	-1.1	-1.4	-0.8	-1.1	-0.7
Ulcerative Colitis (UC)	0.3	0.5	2.6	-0.6	-0.5	-0.7	-1.6	1.2	0.4	-1.1	0.1	-0.1	0.2	-0.1	-0.2	1.1	-0.1	-0.8	-0.3	-1.5	-0.9	-0.4	-0.5	-0.5	-0.3	-0.8	-0.4	-0.1
Fasting Glucose	0.3	0.4	2.0	-0.1	-1.0	-0.1	0.4	-0.3	-0.2	0.3	0.7	-1.2	0.4	-0.2	0.2	-0.6	-0.6	-0.9	-0.2	-0.7	0.1	-1.4	-0.1	-0.0	-0.7	-0.4	-0.0	-1.1
Relative age of first facial hair	0.3	0.6	1.8	-0.3	-0.8	0.2	-0.0	-1.0	-1.3	-0.5	0.3	-1.2	0.7	-0.4	0.2	-1.3	-0.3	-0.6	-0.4	-0.8	-0.5	-1.3	-0.8	-0.5	-0.7	-0.3	-0.5	-1.2
Current tobacco smoking	0.3	0.4	1.8	0.9	0.2	0.0	0.1	1.3	-0.3	-0.4	-0.3	0.5	-1.3	-0.1	-0.1	0.3	1.2	0.2	-0.1	0.8	0.3	1.3	1.0	0.8	0.3	-0.0	0.7	0.2
Fed-up feelings	0.3	0.5	1.7	0.7	1.1	0.7	0.2	0.3	-0.3	0.3	0.6	0.4	-0.2	0.8	0.4	1.0	0.7	1.2	1.1	-1.3	0.8	0.5	0.4	-0.1	1.1	1.0	-0.1	0.7
Taking other prescription medications	0.3	0.4	1.9	-1.0	0.2	-0.0	1.0	-1.2	-0.1	-0.7	-0.7	-0.1	-1.0	-0.5	-0.6	0.4	-0.8	-0.7	-0.4	-0.6	-0.1	-0.4	-1.4	0.2	-0.3	-1.0	0.2	-0.3
Frequency of tenseness / restlessness in last 2 weeks	0.3	0.5	2.4	0.4	-0.3	-0.3	-0.1	0.8	1.5	-0.8	-0.3	0.1	-1.5	-0.2	-0.8	0.8	0.3	0.5	0.7	-0.5	-0.2	0.9	0.1	0.4	0.8	0.7	0.3	0.6
Illnesses of siblings	0.3	0.4	1.5	0.7	-0.9	-0.4	-0.6	1.2	0.2	-0.8	-0.3	-0.7	-0.2	-0.6	-0.3	0.3	0.8	-0.2	-0.9	1.2	-0.6	0.5	0.8	-0.4	-1.1	0.3	-0.4	-0.0
Forced expiratory volume in 1-second (FEV1)	0.3	0.9	3.5	0.8	0.6	1.6	-1.2	0.4	-1.1	1.1	1.4	0.9	0.9	1.2	1.9	1.1	0.5	0.8	-0.0	0.1	0.1	-0.2	1.2	0.9	0.5	-0.3	0.9	0.6
Qualifications: A levels/AS levels or equivalent	0.3	0.6	2.0	-0.6	-0.6	-0.2	0.0	-1.2	-1.0	0.3	0.7	-1.0	-0.8	-0.1	0.3	-1.4	-0.9	-0.8	-1.1	0.6	-1.1	-1.2	0.0	0.0	-1.1	-1.1	0.0	-0.5
Illnesses of mother	0.3	0.4	1.6	-0.9	-0.9	-0.4	-0.1	-0.5	-1.2	-0.5	0.5	-0.2	-0.3	-0.4	0.2	0.3	-0.8	-0.7	-0.7	-0.5	-1.1	-0.7	-0.6	-0.5	-0.6	-1.0	-0.5	-0.6
Forced expiratory volume in 1-second (FEV1), Best measure	0.3	1.1	4.2	1.2	0.6	1.7	-0.8	0.7	-0.6	1.2	1.4	0.9	1.0	1.2	2.0	0.5	0.9	1.3	1.1	-0.3	0.8	-0.0	1.3	1.0	1.1	0.6	1.0	0.8
Loud music exposure frequency	0.3	0.3	1.1	-0.3	-0.5	-0.8	-0.4	0.5	0.2	-1.0	-0.4	-0.6	-0.5	-0.9	-0.8	-0.9	0.2	-0.6	-0.5	-0.4	-0.7	-0.0	-0.3	-0.6	-0.6	-0.4	-0.6	-0.7
Medication: Ventolin 100micrograms inhaler	0.3	0.4	1.4	-0.2	0.7	0.0	0.9	-0.6	-0.1	-0.4	-0.5	0.7	0.1	0.2	-0.7	1.2	-0.1	0.4	0.4	-0.1	1.0	0.6	-0.3	1.1	0.6	0.3	1.1	0.8
Chronic bronchitis/emphysema (mother)	0.3	0.4	1.2	-0.5	-0.1	-0.6	-0.2	0.5	-0.2	-0.5	-0.6	-0.3	0.9	-0.7	-0.8	-0.5	0.1	-0.6	-1.1	-0.6	-0.5	0.1	-1.0	-0.8	-0.5	-0.6	-0.8	-0.7
High blood pressure (siblings)	0.3	0.4	2.6	-0.8	0.7	0.2	0.1	-1.4	0.0	0.7	0.3	-0.1	0.6	0.3	-0.0	-0.6	-0.9	0.2	0.7	-1.2	-0.2	-0.6	-1.6	0.0	0.8	-0.3	-0.0	-0.2
Forced vital capacity (FVC), Best measure	0.3	1.0	3.8	-0.2	0.8	1.4	0.2	-1.2	-1.6	1.5	1.8	0.1	0.6	1.5	1.9	0.6	-0.8	0.6	0.6	-1.1	0.3	-1.4	0.7	0.2	0.5	-0.3	0.3	0.4
Age at first live birth	0.3	0.5	2.0	-0.1	-1.2	-1.0	-0.9	0.2	0.0	-1.1	-0.8	-1.4	-1.1	-0.8	-1.0	-1.3	-0.3	-0.5	0.1	-0.5	-0.4	-0.0	-0.3	-0.5	-0.1	0.3	-0.5	-0.6
Medication: Blood pressure	0.3	0.6	2.6	-0.4	-0.2	-0.6	-0.3	-0.3	1.0	-0.9	-0.9	-0.9	-0.9	-0.8	-1.0	-0.5	0.1	-0.6	0.2	0.1	-0.3	-0.1	-1.1	-1.5	-0.5	0.2	-1.6	-1.1
Alcohol intake frequency.	0.3	0.8	3.1	-1.4	1.1	0.0	0.2	-1.8	-0.8	0.2	-0.4	0.7	0.8	-0.0	-0.0	1.5	-1.0	-0.9	-1.4	-0.9	-0.5	-0.4	-1.4	-0.3	-0.4	-1.4	-0.2	-0.7
Supplements: Vitamin C	0.3	0.3	1.9	-0.4	-0.5	-0.6	-1.4	0.1	1.3	-0.8	-0.2	-0.2	0.6	-0.4	-0.7	0.1	-0.1	-0.2	0.4	-0.5	0.2	-0.3	0.1	0.3	-0.5	0.4	0.4	0.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.3	0.4	1.3	0.2	0.9	0.9	-0.5	0.4	0.5	1.1	1.2	0.6	0.7	1.1	0.9	0.1	0.2	0.2	0.0	0.1	-0.4	0.2	0.5	-0.3	0.4	-0.4	-0.3	0.0
Illnesses of siblings: Diabetes	0.3	0.3	2.0	-0.2	0.2	0.8	0.6	-1.4	-0.5	1.0	0.4	-0.1	0.9	0.4	0.6	0.3	-0.7	0.0	0.4	-0.6	0.3	-1.1	0.1	0.2	0.3	-0.1	0.2	-0.2
Medication: Gliclazide	0.3	0.3	1.2	0.3	-0.5	-0.8	-0.6	1.0	0.8	-0.5	-0.9	-0.4	-0.1	-0.8	-1.1	0.4	0.3	-0.0	-0.3	-0.5	-0.0	0.9	0.2	0.2	0.2	-0.0	0.2	0.4
Smoking status: Current	0.3	0.4	1.7	0.9	0.2	0.0	0.1	1.2	0.1	-0.4	-0.4	0.6	-1.3	-0.1	-0.2	0.3	1.0	0.2	0.0	1.0	0.3	1.3	0.9	0.8	0.5	0.1	0.7	0.3
Financial situation satisfaction	0.3	0.3	2.2	0.3	0.3	0.8	1.5	-0.9	0.4	-0.0	0.4	-0.5	-0.7	0.0	0.1	1.1	0.1	0.1	0.2	-0.4	0.4	-0.4	-0.4	-0.6	-0.1	0.0	-0.6	-0.6
Supplements: Fish oil (including cod liver oil)	0.3	0.4	1.7	-0.7	-0.1	0.2	0.3	-0.7	0.7	-0.3	0.2	-0.4	0.2	-0.1	-0.0	1.0	-0.9	-0.5	-0.1	-1.3	-0.4	-1.1	-1.3	-0.3	-0.3	-0.6	-0.3	-0.5
Irritability	0.3	0.5	1.8	0.7	0.7	0.8	-0.3	-0.1	0.5	0.6	0.9	0.2	0.7	1.0	0.7	0.7	0.2	1.4	0.9	-1.0	0.0	0.4	0.5	0.3	1.1	0.7	0.3	1.0
Pain experienced in last month	0.3	0.5	2.3	0.0	0.2	0.2	0.1	0.1	-0.8	0.6	1.3	0.5	-0.4	0.4	0.8	1.0	-0.4	-0.6	-1.2	-0.1	-1.5	-0.1	0.6	0.4	0.0	-1.5	0.4	-0.1
Depressed Affect (Nagel 2018)	0.2	0.5	5.0	0.4	0.5	0.2	0.6	-0.3	0.7	-0.1	0.0	-0.1	-0.3	0.3	-0.2	0.5	0.3	1.0	1.2	-2.2	0.3	0.1	-0.6	-0.3	1.2	1.1	-0.3	0.1
Neuroticism (Nagel 2018)	0.2	0.5	2.6	0.5	0.6	0.4	0.1	-0.3	0.7	0.7	0.6	-0.0	0.9	0.8	0.3	0.4	0.1	1.0	1.1	-1.6	-0.3	0.1	0.1	0.0	1.2	0.9	0.1	0.5
Schizophrenia vs Biploar Disorder	0.2	0.3	1.4	-0.9	0.3	0.1	0.2	-0.8	0.0	0.3	0.3	0.4	-1.2	0.1	0.3	0.2	-0.8	-0.3	-0.5	-0.3	-0.9	-0.4	-0.1	0.4	0.2	-0.8	0.4	0.2
Major Depression (MDD)	0.2	0.3	1.2	0.4	-0.1	-0.2	0.3	1.1	-0.3	-0.3	-0.0	-0.0	-0.3	-0.3	-0.1	-0.5	0.3	-0.3	-0.5	1.1	0.3	0.5	1.0	-0.9	-0.7	-0.0	-0.9	-0.4
HDL Cholesterol	0.2	0.3	1.2	0.5	-0.4	-0.5	-0.8	0.8	0.4	-0.5	-0.3	0.5	0.1	-0.6	-0.5	0.0	0.8	0.1	-0.9	0.5	-1.1	0.4	0.2	-0.1	-0.8	0.2	-0.2	0.1
Primary Biliary Cirrhosis	0.2	0.4	1.3	-0.0	1.1	0.7	0.6	-0.9	-0.2	0.7	-0.5	0.7	1.1	0.1	0.5	0.4	-0.0	-0.4	-0.5	0.6	0.0	0.5	-0.7	-0.2	0.5	-0.8	-0.2	-0.7
Waist Hip Ratio (WHR)	0.2	1.1	5.5	-0.2	1.8	1.3	2.4	-1.0	-0.6	1.2	0.7	0.6	0.5	1.1	0.7	0.5	-0.6	0.9	0.8	-1.7	1.4	-0.7	-0.7	0.3	1.5	0.2	0.3	0.4
Smoking Status	0.2	0.5	1.3	1.1	0.6	0.4	0.6	0.4	0.1	-0.2	0.0	0.6	-0.7	0.2	0.2	0.2	0.8	0.8	0.8	0.3	0.6	0.9	0.9	1.1	0.7	0.6	1.1	1.1
Allergy or Eczema	0.2	0.5	2.4	-0.4	-0.2	-0.7	0.1	-0.6	0.3	-0.9	-1.5	-0.6	-0.3	-0.9	-1.1	-0.2	0.1	-0.2	0.9	-0.8	-0.2	-0.0	-1.5	-0.8	0.2	0.6	-0.8	-0.4
Hypothyroidism (self reported)	0.2	0.4	2.0	-1.3	0.0	0.5	0.4	-1.4	0.2	0.5	0.5	0.2	-0.6	0.2	1.0	-0.5	-1.4	-0.5	-0.1	-0.3	0.0	-0.8	-0.8	-0.1	-0.0	-0.8	-0.1	-0.5
Lung FVC	0.2	1.0	4.6	0.2	1.1	2.1	0.6	-1.6	-1.1	1.3	1.4	0.8	-0.5	1.6	1.8	0.6	-0.5	0.7	0.3	0.9	0.6	-0.8	0.7	0.7	0.3	-0.3	0.6	-0.0
Neuroticism	0.2	0.5	2.7	0.5	0.1	0.2	0.8	-0.6	1.0	0.2	-0.2	-0.2	-0.1	0.1	-0.3	-0.2	0.2	0.9	1.4	-1.7	0.3	0.2	-0.2	0.3	1.2	1.1	0.4	0.5
Tanning	0.2	2.2	10.6	0.0	1.9	1.4	3.3	-2.8	-1.5	1.0	0.6	1.1	0.6	1.4	1.0	0.9	-1.4	1.0	0.9	-1.0	0.4	0.7	-0.9	1.9	2.6	-0.3	1.9	1.2
Sensitivity / hurt feelings	0.2	0.4	2.7	0.2	-0.6	-0.8	-0.2	0.5	1.6	-0.6	-0.2	-0.8	1.2	-0.4	-0.4	0.1	0.3	-0.1	0.7	-0.8	-0.7	-0.2	0.3	-0.9	0.0	0.6	-0.9	0.3
Pack years adult smoking proportion	0.2	0.3	1.2	-0.2	-0.2	0.3	0.2	-0.4	0.2	0.8	0.2	-1.1	0.2	-0.1	-0.1	-0.9	-0.2	-0.8	-0.8	0.3	-0.5	-0.5	-0.6	-0.6	-0.8	-0.8	-0.6	-1.0
Relative age voice broke	0.2	0.3	2.1	-0.2	-0.5	-0.3	0.1	-0.3	-0.6	-0.8	-0.6	-0.1	0.6	-0.7	-1.0	-1.4	0.0	-0.4	-0.4	-0.1	0.0	-0.4	-0.5	0.1	-0.5	-0.3	0.1	-0.5
Nervous feelings	0.2	0.3	3.1	0.4	-0.7	-0.2	-1.8	0.9	0.9	-0.2	0.1	0.1	-0.0	-0.4	0.2	0.2	0.8	0.0	-0.3	-0.5	-0.7	0.2	0.6	-0.1	-0.7	0.3	-0.1	0.3
Had menopause	0.2	0.3	1.0	0.3	-0.2	0.4	0.6	-1.0	0.2	-0.2	-0.2	-0.4	-0.9	-0.1	-0.1	0.1	0.0	-0.1	0.4	0.4	-0.1	-0.3	-0.2	-0.9	-0.3	0.6	-0.9	-0.9
Heart attack	0.2	0.3	1.1	-0.1	-0.3	-0.4	-0.5	1.0	0.4	-0.9	-0.2	-0.2	-0.5	-0.4	-0.2	-0.0	0.3	-0.3	-0.7	0.5	-1.0	0.3	-0.5	-0.9	-0.8	-0.4	-0.9	-0.4
Allergy	0.2	0.5	3.0	-0.4	-0.6	-0.2	-1.7	0.4	0.2	0.7	1.3	-0.1	0.1	0.6	1.1	-1.2	-0.5	-0.2	-1.0	0.1	-0.4	-1.0	1.1	-0.2	-1.0	-0.5	-0.2	-0.1
Diabetes (self-reported)	0.2	0.3	1.4	-0.5	-0.4	-0.3	-0.3	-0.5	0.8	0.3	-0.8	-0.7	0.6	-0.7	-0.3	-0.1	-0.4	-0.5	-0.5	0.4	-0.4	0.5	-1.2	0.0	-0.2	-0.4	0.0	-0.4
Neuroticism score	0.2	0.4	3.3	0.4	0.0	0.1	0.4	0.2	1.4	0.2	0.3	-0.4	0.4	0.3	0.2	0.0	0.3	0.8	0.9	-1.8	-0.1	0.2	0.1	-0.3	0.9	0.8	-0.3	0.3
Time employed in main current job	0.2	0.2	1.3	0.4	0.1	0.3	-1.2	0.9	0.4	0.2	-0.3	0.2	0.4	-0.1	0.1	-0.4	0.7	-0.5	-0.2	0.2	-0.0	0.2	0.0	0.0	-0.4	-0.5	0.0	-0.2
Hair/balding pattern: Pattern 3	0.2	0.2	2.2	-0.8	0.3	0.2	-1.5	-0.2	0.7	0.3	0.3	0.2	0.2	-0.2	0.3	-0.1	-0.2	-0.5	-0.3	0.6	-0.0	-0.0	-0.3	-0.3	-0.5	-0.6	-0.3	-0.1
Medication: Cholesterol lowering	0.2	0.4	1.4	0.6	-0.0	0.3	0.7	-0.0	1.1	-0.5	-0.6	-0.8	0.8	-0.4	-0.2	-0.8	0.5	0.0	1.2	-0.3	0.6	-0.0	-0.6	-0.6	0.3	0.6	-0.6	-0.5
Standing height	0.2	1.7	6.5	-1.6	-0.9	-0.5	0.3	-1.5	-2.3	0.7	1.9	-1.2	-0.6	0.6	1.1	0.3	-2.5	-0.6	-1.0	-1.7	-1.5	-2.4	0.6	-1.3	-1.1	-1.1	-1.2	-0.1
Exposure to tobacco smoke at home	0.2	0.2	0.9	0.4	0.1	0.3	0.1	-0.1	0.9	-0.1	0.1	0.1	-0.0	0.2	-0.3	0.5	0.5	0.6	0.9	-0.8	0.4	0.1	0.4	0.1	0.1	0.8	0.1	0.8
Peak expiratory flow (PEF)	0.2	0.4	1.9	0.9	-0.4	-0.3	-0.4	1.2	0.7	-0.8	-0.6	0.0	-0.6	-0.4	-0.4	-0.0	1.1	0.1	0.0	0.1	0.3	0.6	0.4	1.4	0.2	0.1	1.4	0.6
Medication: Paracetamol	0.2	0.3	1.8	-1.0	0.0	-0.0	-0.1	-1.3	-0.7	-0.3	0.1	-0.4	0.5	0.1	-0.2	0.4	-1.1	-0.5	0.0	-0.3	-0.3	-0.7	-0.5	-0.3	-0.4	-0.3	-0.3	-0.0
Headache pain in last month	0.2	0.4	1.2	-0.4	-0.4	0.3	0.5	-0.4	-1.1	0.2	-0.9	-0.5	0.8	-0.1	-0.1	-0.3	0.2	0.0	0.3	-0.6	1.0	-0.5	-1.1	-0.8	-0.2	0.2	-0.8	-0.9
Hypothyroidism/myxoedema (self-reported)	0.2	0.5	1.4	-1.1	-0.3	0.4	-1.2	-0.9	-0.7	0.3	0.4	0.4	-0.7	0.2	1.2	-0.2	-1.1	-0.7	-0.6	1.1	0.1	-0.7	-0.2	-0.0	-0.6	-0.8	-0.0	-0.6
Medication: Allopurinol	0.2	0.3	2.4	0.3	-0.2	0.1	-0.1	0.5	-0.4	-0.9	-0.5	-0.1	0.6	-0.5	0.0	0.1	0.4	-0.5	-0.7	1.5	-0.1	0.4	-0.1	0.4	-0.5	-0.3	0.4	-0.0
Medication: Aspirin	0.2	0.3	1.0	-0.4	0.7	0.5	-0.7	-0.8	-0.9	0.3	0.6	0.1	-0.3	0.4	0.5	0.7	-0.6	-0.3	0.2	0.0	-0.2	-1.0	-0.2	-0.6	-0.3	-0.4	-0.6	-0.7
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.3	1.9	-0.7	0.3	0.2	-0.6	-0.2	-1.4	-0.2	0.8	-0.0	0.2	0.5	0.7	0.6	-0.6	0.1	0.3	-1.2	0.3	-0.6	0.2	-0.6	0.1	-0.0	-0.6	0.1
Diabetes diagnosed by doctor	0.2	0.4	1.4	-0.9	-0.2	-0.2	-0.8	-0.9	0.9	0.5	-0.4	-0.5	0.5	-0.6	0.0	0.4	-0.7	-0.8	-0.9	0.4	-0.5	0.0	-1.2	-0.1	-0.5	-1.0	-0.1	-0.5
Diastolic blood pressure, automated reading	0.2	0.6	4.0	0.3	0.8	0.8	0.1	-0.4	-0.7	0.2	-0.5	0.5	-0.0	0.2	-0.3	-0.9	0.5	0.4	1.4	2.0	1.2	0.3	-0.4	-0.8	0.5	0.7	-1.0	-0.7
Myopia	0.2	0.4	1.0	-0.4	0.2	-0.5	0.8	-0.6	0.9	-0.2	0.2	0.8	0.1	-0.4	-0.5	0.8	-0.9	-0.5	-0.3	0.1	-0.2	0.1	0.6	0.9	-0.2	-0.7	1.0	0.9
Supplements: Calcium	0.2	0.3	1.3	-0.7	-0.1	0.3	-1.0	-0.7	0.1	0.2	0.4	0.4	0.2	0.1	0.2	1.1	-0.8	-0.2	-0.6	1.1	-0.1	-0.1	0.1	0.2	-0.5	-0.5	0.2	0.2
Heart attack/myocardial infarction (self-reported)	0.2	0.3	1.4	-0.0	-0.4	-0.5	-0.6	1.2	0.6	-0.9	-0.2	-0.2	-0.5	-0.3	-0.2	0.0	0.4	-0.2	-0.5	0.4	-0.9	0.4	-0.4	-0.7	-0.7	-0.3	-0.8	-0.2
Worry (Nagel 2018)	0.1	0.2	0.6	0.5	0.2	0.1	-0.7	0.2	0.7	0.6	0.3	0.1	0.6	0.3	-0.0	0.2	0.0	0.5	0.3	-0.8	-0.7	0.2	0.6	0.3	0.5	0.5	0.4	0.6
Breast Cancer	0.1	0.4	2.9	0.4	0.0	0.2	-0.0	0.6	-0.4	-0.0	0.1	0.3	-1.6	-0.1	0.2	1.7	0.8	0.6	0.4	-0.4	0.5	0.7	0.7	0.1	0.2	0.3	0.1	0.3
Blood Eosinophil Count	0.1	0.8	3.1	0.8	0.3	0.1	-0.8	0.8	0.9	-0.5	-0.1	1.0	-1.0	0.0	0.1	1.8	0.5	0.8	0.7	-0.3	0.6	0.6	1.3	1.7	0.6	0.9	1.7	1.4
Height	0.1	1.2	5.0	-1.0	-0.5	-0.4	0.5	-0.9	-1.8	1.1	1.9	-0.9	1.2	1.0	1.2	0.5	-2.0	0.1	-0.1	-1.7	-0.4	-2.2	1.2	-0.6	-0.6	-0.3	-0.6	0.6
Medication for hormone replacement therapy	0.1	0.2	0.8	0.3	-0.5	-0.1	0.2	0.4	-0.3	0.3	-0.1	0.1	-0.0	-0.8	-0.4	0.1	0.4	-0.4	-0.3	0.9	0.4	-0.1	-0.1	0.1	-0.8	-0.2	0.0	-0.5
Qualifications: None of the above	0.1	0.3	1.6	-0.5	-0.6	-0.4	0.1	-0.6	0.5	0.1	-1.0	-0.6	-0.5	-0.5	-0.8	-0.2	-0.1	-0.2	-0.0	-0.0	-0.8	0.3	-1.3	-0.3	-0.1	0.1	-0.3	-0.4
Worrier / anxious feelings	0.1	0.3	0.9	-0.0	-0.7	-0.8	-0.3	0.6	0.5	-0.1	-0.5	-0.5	-0.5	-0.3	-0.7	0.4	0.3	0.5	0.1	-0.8	-0.2	0.3	0.3	0.4	-0.1	0.8	0.5	0.9
Hair/balding pattern: Pattern 4	0.1	0.3	2.0	-0.2	0.3	0.7	1.4	-0.4	-0.1	0.5	0.9	0.3	0.5	0.7	0.8	0.5	-0.4	0.1	0.6	-0.6	-0.3	-0.4	-0.5	-0.4	0.6	-0.5	-0.4	-0.3
Comparative height size at age 10	0.1	0.8	3.7	-1.0	-0.5	-1.0	0.5	-0.9	-1.3	-0.4	0.3	-0.8	-1.2	-0.3	-0.2	0.9	-1.5	-0.8	-1.2	-1.9	-0.8	-0.9	0.0	-0.7	-0.6	-1.0	-0.7	-0.5
Chest pain or discomfort	0.1	0.1	0.8	-0.5	0.0	-0.1	0.9	-0.5	0.3	0.1	0.2	-0.0	-0.3	-0.3	0.1	0.1	-0.2	-0.2	-0.5	-0.3	-0.4	-0.2	-0.6	-0.4	-0.4	-0.7	-0.4	-0.2
Friendships satisfaction	0.1	0.1	0.7	0.1	0.5	0.2	0.1	-0.2	0.4	0.1	-0.1	0.2	-0.3	-0.2	-0.1	0.8	0.2	-0.2	0.1	-0.9	0.0	0.0	-0.2	-0.1	0.4	-0.3	-0.1	-0.3
Medication: Aspirin	0.1	0.2	1.0	-0.0	0.6	0.5	-1.0	-0.5	-0.6	-0.2	0.3	-0.1	-0.2	0.3	0.4	0.7	-0.2	-0.2	0.3	0.3	-0.3	-0.5	-0.2	-0.4	-0.1	-0.1	-0.5	-0.7
Commuting to job workplace: Public transport	0.1	0.2	0.9	0.5	0.5	-0.1	-0.8	-0.0	-1.0	0.1	0.2	0.1	0.4	0.4	-0.2	0.7	-0.1	0.3	-0.0	-0.2	0.3	0.3	0.5	0.3	0.6	-0.0	0.3	0.3
Hair Pigment	0.0	1.2	9.5	0.8	-1.2	-1.1	-3.1	2.2	1.1	-0.9	-0.7	-0.7	-0.4	-1.1	-0.5	-1.1	1.6	-0.1	-1.2	0.3	-0.7	0.8	0.6	-0.4	-1.2	0.2	-0.4	0.1
Risk taking	0.0	0.0	0.4	0.0	0.1	0.1	0.2	0.2	-0.3	-0.1	0.0	0.6	0.1	-0.0	0.2	-0.6	0.0	0.1	-0.0	0.1	-0.1	-0.1	0.3	0.0	-0.1	0.1	-0.0	0.0

Hub : Genes

PLAC9

Models

Trait associations