TWAS hub - PLBD1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0480	0.0270	3.2e-02	-0.002	-0.001	0.001	0.006	0.001	6.6e-01	4.3e-01	2.0e-01	4.9e-02	2.2e-01
2	NTR	Blood	0.0886	0.0169	0.0e+00	0.076	0.098	0.110	0.105	0.106	1.7e-23	9.1e-30	1.8e-33	6.7e-32	2.8e-32
3	ROSMAP	Brain Pre-frontal Cortex	0.0483	0.0220	1.0e-02	0.001	0.003	0.004	0.004	0.000	1.9e-01	1.2e-01	9.0e-02	1.0e-01	2.9e-01
4	TCGA	Brain Lower Grade Glioma	0.0789	0.0288	3.9e-06	0.064	0.054	0.062	NA	0.061	9.7e-08	8.0e-07	1.4e-07	NA	1.8e-07
5	TCGA	Soft Tissue Sarcoma	0.1420	0.0530	6.6e-05	0.088	0.100	0.075	NA	0.081	6.3e-06	1.7e-06	3.2e-05	NA	1.5e-05

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5
Glaucoma (self-reported)	5.5	6.5	16.6	1.7	4.1	2.6	2.1	1.2
Schizophrenia (2018)	5.1	10.5	22.5	-2.7	0.4	-2.2	-4.2	-4.7
Eye problems/disorders: Glaucoma	4.8	5.7	14.8	1.6	3.8	2.3	1.8	1.6
Diabetes diagnosed by doctor	3.4	5.5	10.9	-2.6	-0.5	-1.0	-3.3	-2.9
Age started oral contraceptive pill	3.3	4.2	10.0	-0.3	0.4	-2.2	-2.4	-3.2
Mouth/teeth dental problems: Dentures	3.2	5.4	13.4	-0.3	-2.0	-0.5	-3.7	-3.0
Forced expiratory volume in 1-second (FEV1), predicted	3.1	6.4	15.9	2.8	4.0	1.8	2.0	0.9
Medication: Bendroflumethiazide	3.0	4.6	10.3	-1.7	-1.8	-1.7	-3.2	-1.9
Age at First Birth	2.8	4.1	17.5	1.2	4.2	0.7	1.1	-0.1
Reason for reducing amount of alcohol drunk: Health precaution	2.8	3.3	6.7	2.3	2.6	-0.9	1.9	0.1
Schizophrenia (2014)	2.7	6.0	12.7	-2.5	1.0	-1.3	-2.9	-3.6
Past tobacco smoking	2.7	5.0	12.8	0.0	2.0	0.2	3.6	2.9
Townsend deprivation index at recruitment	2.6	3.7	7.2	-1.9	-1.7	-1.0	-2.7	-1.9
Qualifications: None of the above	2.6	5.5	21.6	-1.9	-4.7	1.0	-0.1	1.1
Medication: Omeprazole	2.6	3.2	9.2	3.0	1.5	1.6	1.2	0.7
Serious illness, injury or assault to yourself	2.5	3.1	6.2	0.7	1.3	1.8	2.5	2.0
Schizophrenia vs Biploar Disorder	2.3	3.0	5.2	-1.7	-2.3	-1.8	-1.5	-1.2
Tinnitus: Yes, but not now, but have in the past	2.3	2.5	6.4	0.7	-1.6	2.5	0.9	1.4
Supplements: Glucosamine	2.3	3.0	4.8	-1.8	0.1	-2.2	-2.2	-1.5
Had menopause	2.3	2.9	7.6	-0.1	0.2	-0.8	-2.5	-2.8
Supplements: Fish oil (including cod liver oil)	2.3	3.1	5.2	-2.3	-1.1	-1.7	-2.1	-1.3
Mean Putamen Volume	2.2	2.5	8.7	-1.0	-0.1	0.5	1.6	3.0
Average weekly spirits intake	2.2	2.7	6.5	-0.4	-2.5	-2.6	-0.7	-0.5
Relative age of first facial hair	2.2	4.5	10.6	-0.8	1.8	-3.3	-1.0	-2.6
Stomach or abdominal pain in last month	2.2	2.8	5.1	2.3	1.8	2.1	1.1	0.5
Medication: Ibuprofen (e.g. Nurofen)	2.2	2.8	8.9	-3.0	-2.2	0.1	-0.4	0.5
Verbal and Numeric Reasoning (VNR)	2.0	4.9	9.6	3.1	2.6	2.1	1.5	1.3
Frequency of depressed mood in last 2 weeks	2.0	2.8	5.3	0.8	-0.0	1.7	2.3	2.2
Forced vital capacity (FVC)	2.0	7.6	19.9	2.0	4.5	1.5	3.0	1.7
Alcohol intake versus 10 years previously	2.0	3.0	7.3	-2.0	-2.7	-0.8	-1.7	-0.8
Qualifications: nursing, teaching	2.0	3.1	11.2	1.7	3.3	-0.1	1.0	-0.3
Intelligence (Savage-Jansen 2018)	1.9	5.8	12.5	3.5	3.2	2.0	1.2	0.8
Type 2 Diabetes (T2D) (2018)	1.9	3.5	6.3	-1.8	-1.3	-1.1	-2.5	-2.3
Lung cancer (father)	1.9	2.2	3.0	1.7	-0.9	1.7	1.3	1.7
Forced vital capacity (FVC), Best measure	1.9	6.8	16.2	2.1	4.0	1.1	3.0	1.9
Qualifications: College or University degree	1.9	6.0	19.7	2.7	4.4	-0.2	-0.3	-1.7
Ever smoked	1.9	3.4	7.7	-0.4	-1.6	-0.3	-2.8	-2.6
Bipolar Disorder or Schizophrenia	1.8	4.4	10.3	-1.5	1.7	-0.2	-2.6	-3.2
Smoking Status	1.8	4.3	8.7	-1.4	-3.0	1.7	-2.4	-1.4
Diabetes (self-reported)	1.8	2.9	5.1	-2.3	-0.2	-0.8	-2.1	-2.1
Fluid intelligence score	1.8	3.7	9.5	3.1	2.1	0.5	1.7	1.3
Qualifications: O levels/GCSEs or equivalent	1.8	2.8	13.6	0.2	3.7	-0.2	0.5	-0.3
Leg fat percentage (right)	1.8	6.6	25.3	-1.8	-5.0	-1.6	-1.3	0.5
Supplements: Vitamin C	1.8	2.1	3.3	-1.5	1.5	-0.6	-1.8	-1.5
Medication: Omeprazole (e.g. Zanprol)	1.8	2.1	6.7	2.6	1.2	0.7	1.2	0.8
Medication: Metformin	1.7	2.4	3.4	-1.8	-1.1	-1.1	-1.9	-1.7
Pack years adult smoking proportion	1.7	2.6	5.3	0.3	-2.3	2.3	0.6	1.5
Relative age voice broke	1.7	2.5	7.0	-0.1	0.6	-1.6	-1.6	-2.7
Forced expiratory volume in 1-second (FEV1), Best measure	1.7	5.5	15.8	1.8	4.0	1.1	2.4	1.3
Standing height	1.7	17.3	61.0	4.4	7.8	1.6	1.8	-0.2
Headache pain in last month	1.7	2.9	5.5	0.7	-1.1	1.8	1.9	2.4
Eye problems/disorders: None of the above	1.7	2.0	4.4	-2.1	-1.6	-1.3	-1.0	-0.7
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.7	1.9	3.8	1.9	1.9	1.4	-0.3	-0.5
Number of self-reported non-cancer illnesses	1.7	2.9	7.1	-1.2	-0.4	-2.0	-2.7	-1.3
Leg fat percentage (left)	1.7	6.2	25.1	-1.5	-5.0	-1.3	-1.2	0.6
Medication: Co-codamol	1.6	1.9	5.0	0.5	-2.2	1.9	-0.1	0.8
Forced expiratory volume in 1-second (FEV1)	1.6	5.3	18.9	1.4	4.3	1.0	2.0	0.8
Emphysema/chronic bronchitis	1.6	1.8	6.9	0.9	-2.6	0.6	-1.0	0.3
Crohns Disease (2017)	1.5	3.3	9.4	2.2	3.1	1.0	0.4	-1.0
LDL Cholesterol	1.5	2.3	3.6	1.7	1.2	0.4	1.9	1.9
Diabetes (father)	1.5	1.8	3.7	-1.7	-0.9	-1.9	-1.2	-0.5
Arm fat percentage (right)	1.5	5.8	20.6	-1.7	-4.5	-1.1	-2.0	-0.1
Falls in the last year	1.5	2.0	6.5	-0.8	-2.5	-0.5	-1.3	-0.9
Loud music exposure frequency	1.5	1.6	3.8	-0.9	0.1	0.4	-2.0	-1.8
Mouth/teeth dental problems: Bleeding gums	1.5	1.9	3.3	-1.4	1.5	-1.8	-1.0	-1.1
Medication: Amlodipine	1.5	2.1	5.5	-1.6	-0.0	0.5	-2.3	-1.5
High blood pressure (siblings)	1.5	2.2	3.8	-1.6	-1.9	-1.6	-1.4	-0.2
Arm fat percentage (left)	1.5	6.2	20.5	-1.9	-4.5	-1.6	-2.0	-0.1
Medication: Gliclazide	1.5	1.7	3.2	-1.8	1.0	-0.0	-1.2	-1.7
Pain type(s) experienced in last month: Hip pain	1.5	1.9	3.8	-1.7	-1.9	-0.9	-1.4	-0.6
Alcohol drinker status: Never	1.5	1.8	3.6	-1.0	-1.5	-1.1	1.1	1.9
Bipolar Disorder (2018)	1.4	2.3	5.0	1.0	2.2	2.0	1.0	0.6
Blood Eosinophil Count	1.4	10.4	18.3	-1.9	4.1	-2.1	-3.0	-4.3
Hand grip strength (left)	1.4	3.8	8.2	2.9	0.5	0.8	2.4	2.1
Supplements: Zinc	1.4	1.5	3.7	0.6	1.9	1.0	-1.2	-1.1
Medication: Atenolol	1.4	1.8	3.9	-1.6	-1.0	0.5	-2.0	-1.0
High blood pressure (mother)	1.4	1.9	2.7	-1.6	-1.2	-1.1	-1.6	-1.2
Number of incorrect matches in round	1.4	2.3	8.4	-0.7	-2.9	-1.2	-1.0	-0.1
Illnesses of siblings	1.4	2.0	4.4	0.9	2.1	1.2	1.8	0.1
Worry too long after embarrassment	1.4	2.3	5.1	-0.2	2.3	1.3	1.8	1.1
Had major operations	1.4	1.7	4.4	1.0	0.9	1.4	2.1	0.5
Smoking status: Previous	1.4	2.1	4.9	0.7	-1.4	0.1	-2.2	-1.8
Mouth/teeth dental problems: Mouth ulcers	1.4	2.2	3.8	-0.8	-1.8	-0.7	1.6	2.0
Pack years of smoking	1.4	2.1	4.2	0.5	-2.1	2.1	0.5	1.3
Depression (Nagel 2018)	1.3	2.0	4.5	1.5	-0.0	2.1	0.9	1.6
Alzheimer’s Disease (in mother)	1.3	1.6	3.1	0.9	-1.1	1.1	1.3	1.8
Eye problems/disorders: Diabetes related eye disease	1.3	1.5	3.3	-0.4	0.9	-0.3	-1.8	-1.7
Body mass index (BMI)	1.3	5.4	17.9	-2.2	-4.2	-1.4	-1.5	0.7
Exposure to tobacco smoke at home	1.3	1.5	5.5	-0.9	-2.3	-0.4	-0.8	0.4
Medication: Paracetamol	1.3	2.2	4.4	-1.8	-0.9	0.3	1.5	2.1
Birth weight	1.3	2.8	5.4	1.7	1.2	0.6	2.0	2.3
Leg pain on walking	1.3	1.6	5.6	-2.4	0.5	-0.7	-1.3	-0.4
Commuting to job workplace: Car/motor vehicle	1.3	1.5	3.1	-1.8	-1.6	0.2	0.4	1.3
Commuting to job workplace: Walk	1.3	1.4	3.6	0.2	1.9	-1.3	0.0	-1.3
Mineral and other dietary supplements	1.3	1.8	4.2	0.9	-0.7	0.5	2.0	1.7
Average weekly champagne plus white wine intake	1.3	1.7	8.0	-0.2	2.8	-0.7	-0.1	-0.5
Tinnitus: Yes, now most or all of the time	1.3	1.6	3.8	-0.9	0.4	-1.9	1.6	0.5
Sitting height	1.2	8.3	22.5	3.5	4.7	2.0	1.5	0.2
Financial difficulties in last 2 years	1.2	1.6	4.0	-1.0	-2.0	0.2	-1.5	-1.0
Pulse rate	1.2	2.0	5.1	0.0	-2.3	1.3	-1.6	-0.5
Hair/balding pattern: Pattern 4	1.2	2.8	10.0	-0.5	-3.2	1.5	-1.1	0.7
Body fat percentage	1.2	4.6	18.5	-0.9	-4.3	-1.1	-1.5	0.1
Medication: Ibuprofen	1.2	1.4	3.3	-1.8	-1.4	0.8	0.5	1.1
Breast cancer (self-reported)	1.2	1.4	3.3	-0.1	1.8	0.5	1.6	1.0
Osteoarthritis (self-reported)	1.2	1.6	3.3	-1.1	-0.9	-0.7	-1.8	-1.4
Medication: Paracetamol	1.2	1.9	3.5	-0.2	-0.6	1.7	1.6	1.9
Crohns Disease (2012)	1.1	1.8	6.4	1.4	2.5	-0.4	0.8	0.0
HDL Cholesterol	1.1	1.9	5.3	-0.4	0.2	-1.1	-1.6	-2.3
Height	1.1	22.1	79.6	5.3	8.9	0.9	1.3	-0.5
Other serious medical condition/disability diagnosed by doctor	1.1	1.4	4.0	0.7	0.5	0.5	1.3	2.0
Average weekly fortified wine intake	1.1	1.3	2.8	-0.7	0.9	0.2	1.7	1.6
Hayfever, allergic rhinitis or eczema	1.1	2.3	7.5	1.4	2.7	-0.2	1.4	0.7
Hair/balding pattern: Pattern 2	1.1	1.4	3.5	1.4	1.9	0.7	1.1	-0.3
Prospective memory result	1.1	1.4	3.6	-1.1	-1.9	-0.3	-1.1	-0.9
Chronic bronchitis/emphysema (mother)	1.1	1.2	2.8	1.3	-0.2	1.7	0.9	0.9
Medication: Allopurinol	1.1	1.5	5.9	1.0	2.4	0.4	0.7	-0.1
Alcohol intake frequency.	1.1	2.6	7.1	-1.0	-2.7	0.9	0.6	1.9
Family relationship satisfaction	1.1	1.3	2.8	1.7	0.8	-0.2	1.6	0.9
Illnesses of siblings: Diabetes	1.1	1.4	3.4	-1.0	-1.5	-0.4	-1.8	-0.3
Average weekly red wine intake	1.1	1.7	5.3	0.6	1.0	-2.3	-0.8	-1.0
Ever had bowel cancer screening	1.1	1.3	4.2	1.4	2.0	-0.3	0.4	0.3
Hearing aid user	1.1	1.3	3.6	1.9	-1.0	1.4	-0.1	-0.1
Average weekly beer plus cider intake	1.1	1.5	2.4	-1.6	-1.5	0.2	-1.2	-1.2
Ever depressed for a whole week	1.1	1.3	2.7	0.4	1.2	0.7	1.6	1.3
Vascular/heart problems diagnosed by doctor	1.1	2.9	6.9	2.1	0.8	0.8	2.6	1.4
Irritable Bowel Disease (IBD)	1.0	2.5	8.5	1.1	2.9	1.3	0.6	-0.9
Neuroticism (2016)	1.0	1.4	3.8	-1.9	-0.2	-0.3	-1.0	-1.4
Current tobacco smoking	1.0	1.6	4.8	-1.6	-2.2	0.8	-0.3	-0.1
Fed-up feelings	1.0	1.7	2.4	0.1	-1.5	1.5	1.5	1.4
Frequency of unenthusiasm / disinterest in last 2 weeks	1.0	1.4	5.5	0.6	-0.7	2.4	0.1	0.6
High blood pressure	1.0	2.9	7.8	-2.0	-0.6	-0.6	-2.8	-1.3
Medication: Ramipril	1.0	1.3	4.0	0.9	-1.1	0.7	0.5	2.0
Noisy workplace	1.0	1.3	2.0	-0.9	-1.0	1.0	-1.2	-1.4
Qualifications: A levels/AS levels or equivalent	1.0	2.2	9.3	0.7	3.0	-0.7	0.6	-0.4
Medication: Lansoprazole	1.0	1.2	2.6	0.4	-1.3	-0.6	-1.6	-1.1
Tense / ‘highly strung’	1.0	1.6	4.4	-0.9	-0.3	-0.5	-2.1	-1.6
Gout (self-reported)	1.0	1.4	5.4	0.4	2.3	-1.0	0.8	0.1
Overall health rating	1.0	2.2	5.7	-1.4	-2.4	0.2	1.0	1.5
Medication: Aspirin	1.0	1.3	3.8	-0.3	-0.7	-0.0	-1.9	-1.5
Knee pain experienced in last month	1.0	1.5	4.8	-2.2	-1.6	-0.3	-0.3	0.0
Osteoporosis (self-reported)	1.0	1.2	4.2	-0.0	1.1	-2.1	-0.3	-0.7
Medication: Aspirin	1.0	1.3	3.3	-0.2	-0.8	-0.2	-1.8	-1.6
Medication: Blood pressure	1.0	1.8	4.3	-0.1	-1.4	0.2	-2.1	-1.7
Diastolic blood pressure, automated reading	1.0	3.2	7.2	-2.5	-2.7	-1.1	-0.5	0.9
Supplements: Calcium	1.0	1.1	1.4	-0.5	1.2	1.1	-1.2	-1.2
Deep venous thrombosis (DVT) (self-reported)	1.0	1.3	2.3	-1.1	1.4	-1.5	1.1	0.2
Coronary Artery Disease (CAD)	0.9	1.1	1.6	1.3	0.5	-1.2	1.1	1.0
Severe depression (siblings)	0.9	1.1	2.9	0.5	-0.2	0.9	-1.7	-1.1
Trunk fat percentage	0.9	3.5	14.0	-0.2	-3.7	-0.7	-1.7	-0.3
Frequency of tenseness / restlessness in last 2 weeks	0.9	1.4	2.7	-0.2	-1.6	1.4	-1.3	-0.6
Arm fat mass (right)	0.9	3.5	13.0	-1.0	-3.6	-1.0	-1.6	0.2
Blood clot in the leg (DVT)	0.9	1.2	2.6	-1.1	1.1	-1.6	1.0	0.0
Age at first live birth	0.9	1.5	5.4	0.5	2.3	-0.9	-0.8	-0.8
Shortness of breath walking on level ground	0.9	1.1	2.8	-1.1	-1.7	-0.6	-1.1	-0.3
Leg fat mass (right)	0.9	3.6	12.6	-1.4	-3.5	-1.2	-1.4	0.5
Suffer from ‘nerves’	0.9	1.4	2.7	-0.1	1.6	-1.1	-0.9	-1.6
Age at last live birth	0.9	1.3	4.0	0.8	0.5	-0.3	-2.0	-1.3
Long-standing illness, disability or infirmity	0.9	1.4	3.7	1.3	0.0	1.9	1.0	0.8
Smoking status: Current	0.9	1.5	3.6	-1.6	-1.9	0.7	-0.7	-0.6
Medication: Lisinopril	0.9	1.1	2.5	-0.7	-0.3	0.9	-1.3	-1.6
Risk taking	0.9	1.3	4.8	-2.2	-0.1	0.2	-1.3	-0.3
Leg fat mass (left)	0.9	3.4	12.3	-1.2	-3.5	-1.1	-1.3	0.6
Worry (Nagel 2018)	0.8	1.6	3.1	0.9	1.2	0.0	-1.7	-1.8
Primary Biliary Cirrhosis	0.8	1.2	3.4	-0.7	1.9	-0.9	-0.1	-1.1
Neuroticism	0.8	2.0	4.7	-1.3	-0.5	-0.4	-2.2	-1.7
Ever had hysterectomy (womb removed)	0.8	0.9	2.0	0.8	-1.4	-0.2	1.0	0.9
Hand grip strength (right)	0.8	2.2	3.6	1.9	1.1	0.1	1.7	1.9
Had other major operations	0.8	1.0	3.0	-0.9	-1.7	0.5	-1.0	0.1
Worrier / anxious feelings	0.8	1.5	4.2	1.3	2.0	1.1	0.7	0.1
Medication for pain relief, constipation, heartburn	0.8	1.4	4.1	1.6	2.0	0.1	0.4	-0.7
Medication: Blood pressure	0.8	1.4	3.5	-1.5	0.0	1.0	-1.9	-0.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.8	1.7	3.2	0.2	1.8	1.2	1.7	1.1
Arm fat mass (left)	0.8	3.2	11.5	-1.1	-3.4	-1.1	-1.4	0.4
Wears glasses or contact lenses	0.8	0.9	3.2	1.8	1.0	0.2	0.6	0.2
Heart attack/myocardial infarction (self-reported)	0.8	1.1	3.0	0.1	0.7	1.7	0.9	1.0
Hearing difficulty/problems: Yes	0.7	1.1	2.5	1.6	0.4	0.2	1.4	0.9
Maternal smoking around birth	0.7	1.0	1.7	1.3	-0.9	0.8	0.7	1.2
Bilateral oophorectomy (both ovaries removed)	0.7	0.9	1.9	0.8	-0.8	0.4	1.0	1.4
Happiness	0.7	0.8	2.4	-0.2	1.5	-1.1	0.5	-0.4
Seen doctor (GP) for nerves, anxiety, tension or depression	0.7	1.0	2.5	-0.8	0.2	0.5	1.3	1.6
Pulse wave reflection index	0.7	0.9	2.7	-0.4	0.2	-1.6	1.1	0.6
Ever highly irritable/argumentative for 2 days	0.7	0.8	1.4	-0.7	-1.1	1.2	0.0	1.0
Medication for cholesterol, blood pressure or diabetes	0.7	1.2	3.7	1.1	-0.3	-0.9	1.9	0.4
Wheeze or whistling in the chest in last year	0.7	1.2	5.1	0.3	-2.3	-0.3	-0.9	0.2
Migraine (self-reported)	0.7	0.8	2.2	1.5	-0.5	-0.5	0.8	0.8
Heart disease (mother)	0.7	0.8	1.8	0.1	-0.1	0.8	1.4	1.3
Qualifications: NVQ or HND or HNC or equivalent	0.7	0.9	2.7	-0.7	-1.7	-0.4	0.4	0.9
Handedness (chirality/laterality): Left-handed	0.7	0.8	1.3	0.8	-0.8	0.4	-1.2	-1.1
Illnesses of father: None of the above (group 1)	0.7	0.8	1.7	0.8	-1.0	1.3	0.6	0.7
Fractured/broken bones in last 5 years	0.7	0.9	1.9	-1.3	-1.4	-0.8	-0.2	-0.0
Major Depression (MDD)	0.6	0.8	1.8	-0.6	0.5	-0.4	-1.3	-1.1
BMI	0.6	3.4	7.5	-2.7	-2.5	-1.6	-0.8	0.4
Allergy or Eczema	0.6	1.6	3.9	1.3	2.0	0.6	1.2	0.8
Hypothyroidism (self reported)	0.6	1.3	3.9	2.0	0.9	-0.9	-0.3	-0.8
Chronotype (morning person)	0.6	1.3	3.1	-0.4	0.0	-1.8	-1.2	-1.4
Number of treatments/medications taken	0.6	1.1	2.6	-1.5	-0.5	-0.3	-1.6	-0.6
Ever used hormone-replacement therapy (HRT)	0.6	0.7	1.7	0.4	0.2	-0.6	-1.3	-1.2
Medication for hormone replacement therapy	0.6	0.7	2.1	1.4	0.6	-0.4	-0.3	-0.9
Heart attack	0.6	0.8	2.5	-0.1	0.5	1.6	0.7	0.9
Impedance of arm (right)	0.6	2.8	5.8	1.8	1.7	1.0	-1.0	-2.4
Father’s age at death	0.6	0.8	1.5	0.6	-0.6	-0.8	1.1	1.2
Hair/balding pattern: Pattern 3	0.6	0.9	2.4	-1.5	-0.3	-0.9	-0.5	1.0
Length of working week for main job	0.6	0.6	1.5	-0.9	-1.2	0.3	-0.9	-0.2
Seen a psychiatrist for nerves, anxiety, tension or depression	0.6	0.8	1.4	-1.0	-0.3	0.6	-0.9	-1.2
Mean time to correctly identify matches	0.6	1.1	2.9	0.4	0.4	1.0	-1.7	-1.1
Whole body fat mass	0.6	2.6	9.9	-0.5	-3.1	-1.0	-1.3	0.3
Comparative height size at age 10	0.6	3.3	9.3	1.8	3.0	1.3	1.3	0.7
Hypertension (Self-reported)	0.6	1.8	5.2	-1.6	-0.4	0.1	-2.3	-0.9
Back pain experienced in last month	0.6	0.9	1.7	-1.3	-0.8	-1.2	-0.1	-0.7
Ever taken oral contraceptive pill	0.6	0.7	1.7	-0.5	-1.3	0.6	0.7	0.8
Mother’s age at death	0.6	0.8	1.9	-0.8	0.7	-0.0	-1.4	-0.9
Commuting to job workplace: Public transport	0.6	0.8	2.6	0.2	1.6	0.6	-0.6	-0.6
Medication: Atorvastatin	0.6	0.7	2.2	0.4	1.5	0.4	-0.3	-1.1
Illnesses of father: High blood pressure	0.6	0.8	1.5	0.3	-1.1	-1.2	-1.0	0.1
Type 2 Diabetes (T2D) (2012)	0.5	0.6	2.5	-1.6	0.1	-0.4	-0.2	-0.6
Ulcerative Colitis	0.5	0.7	2.0	-0.3	0.9	0.0	1.4	0.9
Sensitivity / hurt feelings	0.5	0.9	2.5	-1.6	-0.5	-0.8	-0.6	-0.9
Systolic blood pressure, automated reading	0.5	1.5	6.6	-0.8	-2.6	-0.5	-0.3	0.0
Vitamin and mineral supplements	0.5	0.7	1.2	-0.4	-1.1	0.2	0.9	1.1
Age when periods started (menarche)	0.5	1.2	2.7	-0.2	0.7	-0.6	-1.6	-1.5
Impedance of leg (left)	0.5	2.5	7.0	2.6	0.3	1.8	1.5	0.1
Number of live births	0.5	0.7	2.2	-1.5	-0.9	-0.8	-0.3	-0.1
Impedance of arm (left)	0.5	2.3	4.1	2.0	1.9	0.5	-0.3	-1.9
Breastfed as a baby	0.5	0.7	1.9	-0.7	1.4	-0.8	0.5	0.2
Peak expiratory flow (PEF)	0.5	1.2	3.5	-0.6	1.9	-1.4	-0.1	-0.7
Number of children fathered	0.5	0.6	1.4	-1.2	-0.5	-0.3	-1.1	-0.1
Neck or shoulder pain in last month	0.5	0.8	1.6	-1.3	-1.0	0.5	0.6	0.8
Number of full sisters	0.5	0.6	1.5	-0.4	-1.2	-1.0	-0.5	-0.2
Mood swings	0.5	0.9	1.9	-1.2	-0.8	1.4	-0.0	0.8
Ever had stillbirth, spontaneous miscarriage or termination	0.5	0.5	1.6	-0.6	-0.1	-0.3	-1.3	-0.7
Medication for cholesterol	0.5	0.7	1.9	0.1	0.5	0.3	1.4	1.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.5	0.6	1.1	1.1	0.8	1.0	0.5	0.1
Financial situation satisfaction	0.5	0.6	1.7	-1.3	-0.9	0.5	-0.2	-0.2
Commuting to job workplace: Cycle	0.5	0.5	1.3	0.1	0.2	-1.1	-0.9	-0.7
Myopia	0.5	0.8	1.2	-0.1	-0.8	-1.1	-1.1	-0.9
Alzheimer’s Disease (in father)	0.4	0.5	0.9	-0.4	0.9	-0.9	0.8	0.1
Alzheimer’s Disease (including proxy)	0.4	0.5	1.3	0.4	-0.6	0.6	0.7	1.2
Reaction Time	0.4	0.8	1.8	1.3	0.2	1.3	-0.6	0.1
Bipolar Disorder (2011)	0.4	0.4	1.2	1.1	0.6	0.2	-0.4	-0.4
Body Mass Index (BMI) (2010)	0.4	0.6	1.4	-0.4	-0.0	-1.2	0.8	0.8
Lung FEV1/FVC ratio	0.4	2.2	3.6	-1.5	1.2	-0.5	-1.9	-1.9
Impedance of leg (right)	0.4	1.8	5.4	2.3	0.2	1.4	1.2	-0.0
Multivitamins +/- minerals	0.4	0.5	1.7	-0.2	0.1	-0.3	-1.3	-0.9
Chronic bronchitis/emphysema (father)	0.4	0.4	1.8	-1.3	0.6	-0.1	-0.1	0.2
Trunk fat mass	0.4	1.7	6.4	-0.1	-2.5	-0.6	-1.4	0.0
Alcohol usually taken with meals	0.4	0.7	1.5	-0.8	0.2	-1.1	0.4	1.2
Nervous feelings	0.4	0.7	2.0	1.1	1.4	0.5	-0.1	-0.6
Ever unenthusiastic/disinterested for a whole week	0.4	0.5	1.3	-0.4	0.7	0.3	-1.1	-0.6
Mouth/teeth dental problems	0.4	0.6	1.5	0.5	1.2	0.4	0.9	0.3
Medication: Simvastatin	0.4	0.6	1.3	-0.9	-0.5	-0.2	-1.2	-0.7
Trunk fat-free mass	0.4	2.4	9.3	0.8	3.1	0.6	0.8	1.0
Depression (self-reported)	0.4	0.5	1.2	-1.1	-0.0	1.0	-0.2	-0.0
Illnesses of mother	0.4	0.5	1.4	1.2	0.8	-0.3	0.4	0.2
Trunk predicted mass	0.4	2.3	9.3	0.7	3.1	0.6	0.8	1.0
Birth weight of first child	0.4	0.7	1.0	1.0	0.6	0.7	0.7	1.0
Exposure to tobacco smoke outside home	0.4	0.5	2.3	-0.3	-1.5	-0.2	-0.5	-0.0
Health satisfaction	0.4	0.5	1.2	-0.5	-1.1	0.1	-0.9	-0.1
Mouth/teeth dental problems: Loose teeth	0.4	0.5	1.4	-0.3	0.1	0.5	-1.0	-1.2
Chest pain or discomfort	0.4	0.6	1.4	0.5	-1.2	1.1	-0.1	0.6
Illness, injury, bereavement, stress in last 2 years	0.4	0.4	0.8	0.8	0.8	0.1	0.1	-0.9
Illnesses of father: Heart disease	0.4	0.6	2.0	-0.7	0.4	-1.4	-0.7	-0.2
Friendships satisfaction	0.4	0.5	1.5	1.2	-0.2	-0.3	0.9	0.3
Cholesterol lowering medication	0.4	0.5	1.6	0.3	-0.5	-0.5	-0.7	-1.3
Pain experienced in last month	0.4	0.6	2.3	1.5	0.7	-0.3	-0.2	-0.4
Impedance of whole body	0.4	2.1	6.9	2.6	1.1	1.0	0.5	-1.1
Ulcerative Colitis (UC)	0.3	0.6	1.2	-0.7	1.1	0.9	-0.1	-0.7
Ovarian Cancer	0.3	0.5	2.0	-0.3	-0.4	-1.4	-0.2	-0.2
Lupus	0.3	0.4	1.2	-0.1	-0.1	-1.1	-0.6	-0.8
Rheumatoid Arthritis	0.3	0.3	1.3	-1.2	0.4	0.0	0.1	-0.4
Blood White Count	0.3	2.3	5.6	-2.4	0.8	0.0	-2.1	-0.9
Heel T-Score	0.3	2.2	8.4	0.9	-2.9	-1.2	0.4	0.1
Systolic Blood Pressure	0.3	1.7	7.1	-0.5	-2.7	0.9	0.0	0.6
Respiratory disease	0.3	0.7	2.2	1.5	-1.1	0.1	-0.3	-0.1
Angina	0.3	0.3	0.6	0.2	0.3	0.6	0.8	0.8
Heel bone mineral density (BMD) T-score, automated (left)	0.3	0.7	1.8	0.8	0.7	1.3	0.9	0.3
Qualifications: CSEs or equivalent	0.3	0.4	0.9	-0.3	-0.9	0.3	-0.7	-0.8
Medication: Levothyroxine sodium	0.3	0.5	1.1	1.0	0.2	-0.4	-1.1	-0.7
Waist circumference	0.3	1.0	3.4	-0.7	-1.8	-0.4	-0.4	0.9
Heel bone mineral density (BMD) T-score, automated (right)	0.3	0.8	1.9	0.7	0.6	1.4	0.7	0.7
Allergy	0.3	0.6	1.5	-1.2	-1.2	0.3	0.0	0.1
Hayfever/allergic rhinitis (self-reported)	0.3	0.4	0.7	0.7	0.7	0.8	0.0	0.5
Medication: Cholesterol lowering	0.3	0.4	1.1	-1.0	0.4	0.6	-0.6	-0.4
Hypothyroidism/myxoedema (self-reported)	0.3	0.6	1.7	1.3	0.8	-0.3	-0.4	-0.8
Medication: Ventolin 100micrograms inhaler	0.3	0.4	0.9	0.9	-0.3	0.9	-0.1	-0.3
Comparative body size at age 10	0.3	0.7	1.6	0.7	0.6	-0.3	1.3	1.0
Number of full brothers	0.3	0.3	1.1	-0.4	-1.0	-0.6	0.2	0.3
Pulse wave peak to peak time	0.3	0.3	1.3	-0.5	1.1	-0.1	0.3	0.1
Loneliness, isolation	0.3	0.4	1.1	0.7	-0.7	1.0	0.3	0.3
Irritability	0.3	0.5	1.0	-0.3	-1.0	0.8	-0.9	-0.1
Basal cell carcinoma (self-reported)	0.3	0.4	1.2	0.3	0.0	0.7	-1.1	-0.3
Alcohol drinker status: Previous	0.3	0.4	1.7	-0.4	1.3	-0.3	0.0	-0.1
Depressed Affect (Nagel 2018)	0.2	0.4	1.2	-0.1	-1.0	1.1	-0.2	-0.1
Fasting Glucose	0.2	0.3	0.8	-0.2	-0.9	-0.5	-0.2	0.3
HbA1C	0.2	0.2	1.0	0.3	-0.0	0.1	1.0	0.1
Triglycerides	0.2	0.3	0.7	-0.6	-0.8	-0.2	0.4	0.7
Waist Hip Ratio (WHR)	0.2	0.7	1.3	-0.2	-1.1	1.0	-1.0	-0.4
Cardiovascular Disease	0.2	0.5	1.5	-1.2	-0.2	-0.2	-0.4	0.9
Lung FVC	0.2	0.8	2.0	-0.2	0.6	-0.4	1.4	1.2
Diabetes (mother)	0.2	0.2	0.6	-0.8	-0.3	0.4	-0.3	0.2
Taking other prescription medications	0.2	0.3	0.7	0.2	0.0	0.1	-0.7	-0.8
Diverticular disease/diverticulitis (self-reported)	0.2	0.2	0.5	-0.3	-0.7	-0.4	-0.5	0.0
Pain all over the body in last month	0.2	0.2	0.5	0.1	-0.6	0.0	-0.7	-0.6
Frequency of tiredness / lethargy in last 2 weeks	0.2	0.3	0.6	-0.1	-0.6	0.8	0.3	0.8
Serious illness, injury or assault of a close relative in last 2 years	0.2	0.2	0.3	-0.6	-0.3	0.1	-0.6	-0.5
Pulse wave Arterial Stiffness index	0.2	0.2	0.5	0.7	-0.7	0.4	-0.2	-0.0
Arm fat-free mass (right)	0.2	0.9	2.2	0.3	1.5	-0.6	0.7	1.2
Angina (self-reported)	0.2	0.3	0.5	0.3	0.5	0.6	0.7	0.7
Medication: Seretide 50 evohaler	0.2	0.2	0.8	0.9	-0.2	0.1	-0.4	0.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.2	0.2	0.4	0.3	-0.6	-0.1	-0.6	0.1
Arm predicted mass (right)	0.2	0.9	2.3	0.4	1.5	-0.4	0.7	1.1
Pulse rate, automated reading	0.2	0.7	2.2	0.6	-0.7	1.5	-0.7	0.2
Whole body fat-free mass	0.2	1.3	5.7	0.5	2.4	0.0	0.4	0.7
Leg fat-free mass (right)	0.2	0.9	4.1	0.3	2.0	-0.0	0.1	0.5
Eye problems/disorders: Cataract	0.2	0.2	0.5	0.6	0.3	-0.7	0.4	0.0
Asthma (self-reported)	0.2	0.3	1.1	1.1	-0.2	-0.4	-0.4	-0.0
Whole body water mass	0.2	1.2	5.2	0.4	2.3	0.1	0.4	0.7
Leg predicted mass (right)	0.2	0.9	4.1	0.4	2.0	0.0	0.1	0.5
Guilty feelings	0.2	0.3	1.0	-0.0	-0.1	0.5	1.0	0.7
Unable to work because of sickness or disability	0.2	0.2	0.5	0.3	-0.7	0.4	0.3	0.6
Heart disease (siblings)	0.2	0.3	0.5	0.7	0.6	0.5	0.1	-0.3
Arm predicted mass (left)	0.2	0.9	1.8	0.6	1.4	0.2	0.7	1.3
Neuroticism (Nagel 2018)	0.1	0.3	0.7	0.3	0.5	0.8	-0.5	-0.5
Blood Platelet Count	0.1	1.5	4.0	-2.0	-0.4	-1.0	-1.4	-0.7
Blood Red Count	0.1	0.7	1.6	-0.1	0.8	0.4	-1.1	-1.3
Leg fat-free mass (left)	0.1	0.5	2.2	-0.1	1.5	-0.4	-0.2	0.3
Leg predicted mass (left)	0.1	0.5	2.4	-0.0	1.5	-0.3	-0.1	0.4
Hearing difficulty/problems with background noise	0.1	0.2	0.8	-0.3	0.9	0.0	-0.3	-0.0
Neuroticism score	0.1	0.2	0.7	-0.8	-0.2	0.3	-0.3	-0.3
Hip circumference	0.1	0.5	1.4	0.4	-1.0	-0.4	0.1	1.2
Asthma	0.1	0.3	0.6	0.7	-0.4	-0.8	-0.4	0.1
Miserableness	0.1	0.2	0.4	-0.5	0.6	0.5	-0.0	-0.2
High cholesterol (Self-reported)	0.1	0.3	0.6	-0.5	0.8	-0.2	-0.5	-0.5
Basal metabolic rate	0.1	0.6	2.2	0.4	1.5	0.0	0.3	0.9
Arm fat-free mass (left)	0.1	0.8	1.8	0.5	1.1	0.0	0.8	1.3
Number of operations (self-reported)	0.1	0.1	0.3	0.1	0.1	0.2	0.6	-0.1
Ever had prostate specific antigen (PSA) test	0.1	0.2	0.5	-0.4	0.7	0.2	-0.5	0.0
Breast Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Prostate Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Hair Pigment	0.0	1.3	3.1	0.6	1.3	-0.2	-1.1	-1.8
Tanning	0.0	0.4	0.9	-0.3	-0.5	-0.9	-0.1	-0.7
Weight	0.0	0.2	0.3	0.0	-0.5	-0.5	-0.5	0.6
Time employed in main current job	0.0	0.0	0.1	0.3	-0.1	-0.3	-0.2	-0.1

Hub : Genes

PLBD1

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Trait associations