TWAS hub - PLD2

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.1930	0.0600	5.1e-04	0.092	NA	0.073	NA	0.074	5.7e-08	NA	1.5e-06	NA	1.2e-06
2	GTEx	Artery Aorta	0.2420	0.0790	5.2e-04	0.129	NA	0.105	NA	0.158	1.3e-07	NA	2.2e-06	NA	4.7e-09
3	GTEx	Artery Tibial	0.2838	0.0619	4.4e-07	0.179	NA	0.222	NA	0.195	5.1e-14	NA	2.6e-17	NA	3.2e-15
4	GTEx	Brain Cerebellar Hemisphere	0.3460	0.1230	8.5e-03	0.280	NA	0.161	NA	0.216	6.9e-08	NA	6.3e-05	NA	3.1e-06
5	GTEx	Brain Cerebellum	0.3550	0.1070	4.2e-04	0.207	NA	0.303	NA	0.223	9.4e-07	NA	1.2e-09	NA	3.2e-07
6	GTEx	Cells Transformed fibroblasts	0.3730	0.0650	1.9e-09	0.238	NA	0.267	NA	0.302	7.6e-18	NA	4.4e-20	NA	5.5e-23
7	GTEx	Esophagus Muscularis	0.2270	0.0690	4.7e-04	0.113	NA	0.168	NA	0.149	2.3e-07	NA	2.0e-10	NA	2.3e-09
8	GTEx	Heart Left Ventricle	0.3237	0.0949	4.2e-03	0.134	NA	0.066	NA	0.109	1.3e-07	NA	2.2e-04	NA	2.0e-06
9	GTEx	Stomach	0.1600	0.0680	7.5e-03	0.027	NA	0.030	NA	0.015	1.8e-02	NA	1.4e-02	NA	6.1e-02
10	GTEx	Testis	0.3780	0.1080	3.5e-03	0.018	NA	0.004	NA	0.036	5.3e-02	NA	2.0e-01	NA	9.9e-03
11	GTEx	Whole Blood	0.1420	0.0450	1.3e-04	0.093	NA	0.117	NA	0.129	6.6e-09	NA	7.0e-11	NA	6.7e-12
12	METSIM	Adipose	0.1597	0.0348	1.4e-14	0.174	0.123	0.174	0.178	0.173	2.5e-25	6.3e-18	2.9e-25	6.1e-26	3.4e-25
13	YFS	Blood	0.1109	0.0252	0.0e+00	0.112	0.078	0.110	0.114	0.110	1.1e-34	2.3e-24	4.6e-34	2.8e-35	4.1e-34
14	TCGA	Breast Invasive Carcinoma	0.0166	0.0090	7.7e-03	0.001	0.003	0.000	NA	-0.001	1.6e-01	8.0e-02	2.6e-01	NA	5.9e-01
15	TCGA	Prostate Adenocarcinoma	0.1180	0.0400	2.2e-08	0.019	0.073	0.087	NA	0.083	3.7e-03	3.9e-08	2.1e-09	NA	4.8e-09
16	TCGA	Testicular Germ Cell Tumors	0.1140	0.0600	8.1e-03	0.126	0.045	0.077	NA	0.089	3.3e-05	1.1e-02	1.1e-03	NA	4.6e-04
17	TCGA	Thyroid Carcinoma	0.0490	0.0270	6.0e-03	0.017	0.013	0.024	NA	0.018	7.2e-03	1.8e-02	1.9e-03	NA	6.9e-03

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17
Qualifications: CSEs or equivalent	5.4	7.1	12.2	2.3	3.2	3.0	3.3	2.9	3.0	2.8	3.5	2.5	3.5	2.3	2.2	1.8	2.0	2.9	-0.6	2.0
Average weekly champagne plus white wine intake	4.7	6.5	10.4	-2.6	-3.1	-2.5	-2.9	-2.5	-2.8	-2.7	-2.7	-2.1	-1.9	-2.5	-3.2	-2.8	-2.4	-2.8	0.7	-1.8
Medication: Atenolol	4.0	5.0	12.7	-2.0	-2.7	-2.4	-2.3	-1.8	-2.7	-2.2	-1.9	-1.6	-3.6	-2.0	-1.6	-1.8	-2.3	-2.3	-1.6	-2.2
Diabetes (self-reported)	4.0	6.1	9.3	2.3	3.0	2.5	2.7	2.7	2.7	3.1	2.4	2.1	2.8	2.1	2.3	2.0	3.1	2.4	1.0	2.2
Medication: Metformin	3.8	5.4	11.6	2.0	2.6	2.0	1.9	2.2	2.7	2.5	1.8	1.4	3.4	2.2	1.6	1.0	3.3	2.0	2.8	2.7
Blood White Count	3.6	26.8	40.4	4.9	6.0	4.9	4.8	4.8	6.0	6.1	4.2	4.3	5.4	5.5	5.2	4.3	6.1	6.4	2.0	5.6
Diabetes diagnosed by doctor	3.6	5.9	11.9	2.0	2.9	2.3	2.8	3.1	2.5	2.9	2.4	2.2	3.0	1.7	2.0	1.4	3.4	2.4	0.7	1.9
Alzheimer’s Disease (including proxy)	3.4	4.9	12.6	2.6	2.2	2.7	1.4	2.0	2.3	2.3	1.4	1.8	2.3	2.5	2.4	2.3	2.1	3.6	-0.4	1.8
Illnesses of mother	3.4	4.3	7.2	2.6	2.1	2.7	1.8	2.1	2.1	2.2	1.8	2.2	1.6	2.3	2.5	2.4	1.1	2.2	0.2	1.8
Leg fat mass (right)	3.4	13.2	20.3	3.8	4.1	3.2	2.7	1.9	4.5	4.2	2.2	2.2	4.5	4.1	3.5	3.3	4.1	4.1	3.7	3.9
Leg fat mass (left)	3.1	12.0	18.9	3.7	3.9	3.0	2.4	1.7	4.3	3.9	1.9	1.9	4.3	4.0	3.4	3.1	3.9	4.0	3.7	3.9
Type 2 Diabetes (T2D) (2018)	2.9	5.4	12.4	2.0	2.7	2.0	2.5	2.9	2.5	2.7	2.1	2.2	2.7	1.9	1.7	1.2	3.5	2.6	0.5	2.3
Heel bone mineral density (BMD) T-score, automated (left)	2.9	6.7	11.7	3.0	3.0	2.1	2.0	1.8	3.0	2.5	1.7	2.8	2.3	2.6	2.8	2.9	3.3	3.4	0.5	2.6
Leg fat percentage (right)	2.9	10.7	17.3	3.5	3.9	2.8	2.6	2.2	4.2	4.1	2.1	2.0	3.5	3.8	3.5	3.2	3.5	3.7	2.7	3.1
Body mass index (BMI)	2.8	11.8	19.4	4.0	3.8	3.1	2.0	1.4	4.4	3.9	1.4	2.4	4.3	4.2	3.6	3.5	3.5	4.0	3.2	3.4
Eye problems/disorders: Cataract	2.8	3.2	5.5	-2.3	-2.0	-1.9	-1.4	-1.7	-1.9	-1.9	-1.1	-1.3	-1.5	-1.8	-2.3	-2.3	-1.3	-2.3	1.2	-1.5
Leg fat percentage (left)	2.8	10.2	16.7	3.6	3.8	2.6	2.5	1.9	4.1	3.9	2.0	1.8	3.3	3.8	3.5	3.2	3.5	3.9	2.5	3.2
Waist circumference	2.7	9.7	14.8	3.4	3.4	3.0	2.3	1.5	3.6	3.8	2.0	1.8	3.8	3.4	3.2	2.8	3.8	3.7	2.6	3.1
Arm fat percentage (left)	2.7	10.8	17.6	3.4	3.5	3.0	2.3	1.8	4.0	3.9	1.9	2.5	4.2	3.8	3.1	2.5	3.8	3.7	3.4	3.6
Mother’s age at death	2.7	3.4	6.0	-1.7	-2.4	-1.6	-2.4	-1.5	-2.2	-1.2	-2.4	-1.0	-2.2	-1.8	-1.4	-1.8	-1.0	-2.0	-0.3	-2.4
Primary Biliary Cirrhosis	2.6	3.7	6.8	-2.3	-2.1	-1.5	-0.8	-1.5	-2.5	-1.7	-0.4	-2.1	-2.1	-2.6	-1.8	-1.9	-1.5	-2.0	-2.3	-2.4
BMI	2.6	15.3	23.8	4.4	4.3	3.4	2.3	2.1	4.9	4.5	1.5	3.1	4.8	4.6	4.0	3.9	4.3	4.5	3.9	3.9
Arm fat mass (right)	2.6	10.7	20.1	3.5	3.5	2.9	2.0	1.4	4.1	3.6	1.5	2.0	4.5	3.9	3.0	2.7	3.5	3.8	3.8	3.7
Qualifications: NVQ or HND or HNC or equivalent	2.6	3.2	5.5	2.2	2.2	2.1	1.8	1.7	2.2	1.9	1.4	0.6	2.1	2.0	2.0	1.8	0.0	2.3	-1.2	0.5
Arm fat mass (left)	2.6	10.7	20.9	3.4	3.5	2.8	2.2	1.6	4.1	3.5	1.6	2.0	4.6	3.9	3.0	2.6	3.5	3.8	3.8	3.7
Supplements: Fish oil (including cod liver oil)	2.6	3.4	5.7	-2.2	-2.2	-2.1	-1.1	-1.6	-2.1	-2.2	-1.2	-1.8	-2.3	-1.7	-2.3	-2.4	-1.3	-2.2	0.5	-0.9
Age started oral contraceptive pill	2.6	3.3	9.4	-0.8	-2.1	-1.9	-2.6	-3.1	-1.6	-1.8	-2.2	-1.6	-1.9	-0.8	-0.6	-0.1	-2.5	-1.0	-1.3	-1.9
Age when periods started (menarche)	2.5	5.9	12.8	-2.5	-2.7	-2.4	-1.8	-2.2	-2.8	-2.8	-1.5	-3.6	-2.4	-2.8	-2.3	-2.6	-2.2	-2.6	-0.4	-2.3
Arm fat percentage (right)	2.5	10.0	14.9	3.3	3.4	2.8	2.2	1.6	3.8	3.8	1.7	2.7	3.9	3.7	3.1	2.6	3.7	3.6	3.2	3.3
Financial difficulties in last 2 years	2.3	3.1	6.7	2.0	2.2	1.6	2.1	2.0	2.0	1.8	2.0	1.4	1.1	1.7	2.3	2.6	0.9	1.5	-1.0	0.8
Breast Cancer	2.1	5.1	10.7	-2.4	-2.6	-2.1	-1.6	-2.0	-3.1	-2.2	-1.2	-1.3	-2.9	-3.3	-1.6	-1.7	-1.7	-1.9	-2.1	-3.2
Body fat percentage	2.1	8.2	12.6	2.9	3.2	2.4	2.4	1.6	3.5	3.5	1.9	1.8	3.3	3.2	2.8	2.3	3.5	3.4	2.9	3.1
Whole body fat mass	2.1	8.8	14.4	3.0	3.2	2.6	2.2	1.3	3.6	3.3	1.7	1.4	3.8	3.4	2.7	2.4	3.6	3.4	3.7	3.5
Illness, injury, bereavement, stress in last 2 years	2.1	2.5	5.2	-1.8	-1.8	-1.7	-1.7	-2.0	-1.5	-1.9	-1.7	-1.4	-1.0	-1.3	-1.9	-2.3	-1.2	-1.2	1.4	-0.6
High blood pressure (mother)	2.0	2.8	5.5	-1.7	-1.9	-2.1	-2.3	-1.7	-1.7	-1.8	-2.0	-1.1	-0.9	-1.5	-1.9	-1.7	-1.2	-1.9	-0.7	-1.4
Alcohol intake versus 10 years previously	2.0	3.0	6.6	1.3	2.2	2.2	2.5	2.0	1.5	1.7	2.6	1.1	2.1	0.7	1.5	1.9	0.5	1.6	-1.6	0.0
Lung cancer (father)	2.0	2.3	4.2	-0.9	-1.5	-1.6	-1.7	-2.1	-1.5	-1.5	-1.7	-1.3	-2.1	-1.0	-1.0	-0.3	-1.6	-1.7	-1.5	-1.7
Handedness (chirality/laterality): Left-handed	2.0	2.3	5.6	-1.2	-1.8	-1.6	-1.4	-1.3	-1.7	-1.5	-0.8	-1.7	-1.7	-1.2	-1.5	-0.9	-2.4	-1.9	0.3	-2.0
Commuting to job workplace: Cycle	1.9	2.3	4.1	-1.4	-1.7	-1.5	-1.9	-1.7	-1.5	-1.7	-2.0	-0.6	-1.0	-1.3	-1.4	-1.6	-2.0	-1.4	-0.3	-1.6
Fasting Glucose	1.8	2.1	5.4	1.8	1.5	1.4	0.9	1.4	1.9	1.4	0.4	-0.2	1.0	2.2	1.5	1.6	1.1	2.3	0.3	1.8
Blood Platelet Count	1.8	21.1	65.6	5.1	3.1	4.8	0.5	-0.3	5.2	5.7	0.4	2.5	5.5	6.7	4.1	3.4	4.1	2.1	8.1	6.7
Current tobacco smoking	1.8	3.0	6.4	1.9	2.1	1.3	1.4	1.5	2.3	1.8	1.6	-0.2	2.0	2.4	1.3	1.1	1.7	1.4	1.3	2.5
Number of incorrect matches in round	1.8	2.9	8.3	-1.9	-1.7	-2.0	-0.4	-0.8	-2.1	-1.3	-0.5	-2.9	-2.3	-2.0	-1.8	-1.8	-1.5	-1.7	-0.8	-1.3
Qualifications: None of the above	1.8	3.9	8.2	-2.6	-1.8	-1.5	-0.2	-1.6	-2.6	-1.5	-0.4	-2.5	-2.1	-2.9	-1.9	-1.9	-1.4	-1.7	-2.8	-1.8
Headache pain in last month	1.8	3.1	8.3	1.7	2.0	2.1	2.1	1.6	1.9	1.7	1.9	-0.8	1.6	1.8	1.3	1.5	1.4	2.0	0.2	2.9
Medication: Aspirin	1.8	2.3	4.9	-1.0	-1.5	-1.9	-1.9	-2.2	-1.3	-1.9	-2.0	-1.2	-1.3	-0.9	-1.1	-1.6	-1.4	-1.7	-0.4	-1.5
Trunk fat mass	1.7	7.5	13.6	2.6	2.9	2.3	2.0	1.1	3.3	3.0	1.6	1.3	3.7	3.1	2.4	1.9	3.4	3.2	3.6	3.3
Heel T-Score	1.6	13.1	24.1	3.9	4.5	3.3	3.7	3.8	3.9	3.7	3.1	2.9	2.8	3.0	4.3	4.8	2.8	4.9	-3.2	1.3
Trunk fat percentage	1.6	6.6	10.8	2.5	2.8	2.2	2.0	1.1	3.1	3.0	1.6	1.5	3.2	2.9	2.4	1.9	3.3	3.0	2.8	2.9
Had menopause	1.6	2.0	4.0	-1.5	-1.2	-1.7	-0.3	-1.0	-1.7	-1.1	-0.1	-1.8	-2.0	-2.0	-1.1	-1.2	-1.1	-1.6	-1.4	-1.9
Hip circumference	1.6	6.8	13.9	2.8	2.6	2.2	1.4	0.6	3.2	2.9	0.9	1.5	3.7	3.2	2.0	1.8	3.0	3.1	3.7	3.1
Medication: Allopurinol	1.6	2.1	4.8	-1.9	-1.2	-1.7	-0.2	-1.2	-1.8	-1.4	-0.2	-1.4	-1.5	-2.2	-1.2	-1.3	-1.5	-1.2	-1.5	-1.8
Qualifications: O levels/GCSEs or equivalent	1.5	2.4	6.3	0.9	1.5	0.6	1.2	2.0	1.7	0.7	1.0	2.3	2.5	1.2	0.2	0.4	2.2	1.7	2.2	1.4
Medication for hormone replacement therapy	1.4	1.5	3.5	0.9	1.5	1.6	1.8	1.1	1.4	1.2	1.5	0.4	1.9	1.1	0.6	0.8	1.0	0.7	0.8	1.6
Diverticular disease/diverticulitis (self-reported)	1.4	1.6	3.7	0.7	1.7	1.2	1.9	1.3	1.2	1.3	1.8	0.8	1.5	0.4	1.4	1.2	1.3	1.2	-0.7	0.6
Hair/balding pattern: Pattern 2	1.4	1.8	7.4	1.9	1.3	1.2	0.6	0.5	1.4	1.3	0.7	1.3	0.4	1.6	2.1	2.7	0.3	1.6	-0.6	0.3
Gout (self-reported)	1.4	1.9	3.6	-1.7	-1.1	-1.6	-0.4	-1.1	-1.5	-1.5	-0.3	-1.3	-1.9	-1.7	-1.2	-1.4	-1.4	-1.3	-1.1	-1.5
Shortness of breath walking on level ground	1.4	1.6	4.5	2.1	0.9	1.6	0.0	-0.3	1.4	1.3	0.4	0.9	1.3	2.0	1.5	1.5	1.0	1.6	0.7	1.2
Commuting to job workplace: Car/motor vehicle	1.4	1.6	3.4	1.2	1.7	0.7	1.4	1.1	1.3	1.4	1.3	1.8	0.8	0.7	1.1	1.3	1.5	1.8	-0.7	0.2
Medication: Aspirin	1.4	1.8	4.1	-0.8	-1.3	-1.5	-1.8	-2.0	-1.1	-1.6	-1.9	-1.0	-1.0	-0.7	-0.9	-1.5	-1.2	-1.4	-0.7	-1.4
Hearing difficulty/problems: Yes	1.3	2.0	9.8	-0.9	-1.1	-1.1	-1.7	-1.6	-0.7	-1.1	-1.6	-3.1	-1.2	-0.5	-0.6	-0.9	-1.4	-1.4	1.8	-0.6
Weight	1.3	6.5	13.2	2.8	2.6	2.2	1.5	0.8	3.1	2.7	1.1	1.1	3.6	3.0	2.4	2.3	2.8	2.9	3.5	2.9
Reason for reducing amount of alcohol drunk: Health precaution	1.3	1.5	2.9	1.1	1.2	1.5	1.3	1.7	1.2	1.3	1.1	1.1	1.1	1.2	0.9	0.6	1.4	1.3	-0.3	1.7
Chronotype (morning person)	1.2	2.8	5.4	-1.4	-2.0	-1.8	-2.3	-1.5	-1.4	-1.7	-2.3	-1.8	-1.4	-0.7	-1.7	-2.0	-1.1	-2.0	1.5	-0.7
Other serious medical condition/disability diagnosed by doctor	1.2	1.5	2.6	1.4	1.6	1.1	0.8	0.8	1.6	1.5	0.6	0.6	1.6	1.4	1.4	0.9	1.4	1.6	0.2	1.1
Vitamin and mineral supplements	1.2	1.7	6.7	1.4	0.8	1.3	-0.5	-0.1	1.1	1.8	-0.6	2.6	1.1	1.1	1.6	1.2	1.5	1.5	1.1	0.3
Stomach or abdominal pain in last month	1.2	1.5	3.2	1.5	1.4	1.4	0.6	0.2	1.6	1.5	0.2	0.4	1.5	1.8	1.2	0.5	1.1	0.7	1.5	1.7
Angina (self-reported)	1.2	1.5	2.7	-1.1	-1.6	-0.7	-1.4	-1.6	-1.5	-0.9	-1.4	-1.6	-1.4	-1.2	-0.9	-1.1	-0.9	-1.6	0.7	-0.8
Eye problems/disorders: Glaucoma	1.2	1.4	5.1	-0.8	-1.0	-1.9	-2.2	-1.2	-0.4	-1.4	-2.3	-0.2	-0.5	-0.4	-1.3	-0.7	-1.1	0.1	0.4	-0.6
Alzheimer’s Disease (in father)	1.1	1.2	3.4	1.4	0.8	1.0	-0.1	0.4	1.3	1.0	-0.0	0.6	1.0	1.8	0.9	0.7	1.4	1.5	0.7	1.8
Sensitivity / hurt feelings	1.1	1.8	3.4	1.5	1.7	1.2	1.1	1.1	1.8	0.9	0.8	0.3	1.7	1.7	1.7	0.7	1.2	0.8	1.6	1.8
Leg fat-free mass (left)	1.1	5.6	17.0	2.4	2.0	2.2	0.8	0.2	2.7	2.2	0.6	0.9	3.8	2.8	1.8	1.9	2.5	2.2	4.1	3.0
Multivitamins +/- minerals	1.1	1.4	5.3	-1.2	-1.0	-1.0	0.3	-0.3	-1.3	-1.3	0.4	-2.3	-1.7	-1.1	-1.2	-0.8	-1.3	-1.6	-0.8	-0.4
Leg predicted mass (left)	1.1	5.7	17.1	2.4	2.0	2.2	0.8	0.1	2.7	2.1	0.6	0.9	3.8	2.9	1.8	1.9	2.6	2.3	4.1	3.0
Impedance of arm (right)	1.1	4.9	9.8	-2.9	-2.8	-2.1	-1.2	-0.8	-3.1	-2.0	-0.8	-0.7	-2.8	-2.8	-2.5	-2.9	-1.8	-2.8	-0.9	-1.9
Impedance of arm (left)	1.1	5.0	10.9	-3.0	-2.8	-2.0	-0.9	-0.6	-3.1	-2.2	-0.6	-1.1	-2.6	-2.9	-2.6	-3.3	-1.4	-2.8	-1.1	-1.7
Heart disease (mother)	1.1	1.4	2.5	-1.3	-1.3	-1.4	-0.8	-1.2	-1.3	-1.1	-0.4	-0.8	-1.3	-1.3	-1.1	-1.2	-0.9	-1.6	-0.8	-1.5
Alcohol intake frequency.	1.1	2.6	5.2	1.5	1.9	1.9	2.3	1.5	1.5	1.8	2.1	1.4	1.3	1.2	1.8	2.1	0.3	1.8	-0.3	1.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.1	1.3	2.6	1.1	1.4	1.5	1.2	1.2	1.0	1.3	1.3	0.4	1.6	0.8	1.4	1.0	1.1	1.1	0.0	1.1
Mood swings	1.1	1.9	4.9	1.1	1.6	1.4	2.1	1.6	1.2	1.5	2.2	-0.3	1.5	0.7	1.8	1.8	1.1	0.7	-0.0	0.7
Illnesses of father: None of the above (group 1)	1.1	1.3	3.4	-1.2	-1.3	-0.8	-0.2	0.2	-1.6	-0.8	-0.4	-0.2	-1.4	-1.5	-1.0	-0.0	-1.8	-1.0	-1.5	-1.8
Leg predicted mass (right)	1.1	5.6	14.9	2.5	2.0	2.2	0.8	0.0	2.7	2.1	0.7	1.1	3.8	2.9	1.9	2.0	2.6	2.4	3.9	3.0
Impedance of whole body	1.1	5.7	10.7	-3.0	-2.6	-2.4	-0.7	-0.2	-3.3	-2.4	-0.4	-1.4	-3.3	-3.3	-2.5	-2.7	-2.0	-2.7	-2.2	-2.4
Alzheimer’s Disease (in mother)	1.0	1.2	4.2	1.1	1.2	1.5	1.0	1.2	1.1	0.9	0.7	0.1	1.2	1.0	1.1	1.1	0.7	2.1	-0.7	0.6
Blood Red Count	1.0	10.1	22.5	3.3	3.1	3.7	2.6	2.7	3.1	3.5	2.5	4.2	2.6	2.8	3.6	3.8	2.8	4.7	-0.7	2.1
Eye problems/disorders: Diabetes related eye disease	1.0	1.0	2.4	0.9	0.9	0.7	1.0	0.6	1.0	1.1	0.8	1.5	0.5	1.2	0.6	0.5	1.4	1.5	1.3	0.9
Angina	1.0	1.4	2.8	-1.0	-1.5	-0.6	-1.4	-1.6	-1.4	-0.8	-1.3	-1.7	-1.4	-1.1	-0.7	-1.1	-0.7	-1.4	0.7	-0.7
Alcohol usually taken with meals	1.0	1.7	4.5	-0.9	-1.6	-1.3	-2.0	-1.4	-1.1	-1.8	-2.1	-0.0	-0.8	-0.7	-0.9	-0.9	-1.4	-1.3	0.7	-1.2
Heel bone mineral density (BMD) T-score, automated (right)	1.0	2.3	5.0	2.0	1.5	1.2	0.5	0.6	1.7	1.4	0.2	2.0	0.8	1.7	1.9	1.9	2.2	1.9	0.5	1.3
Illnesses of siblings	1.0	1.5	4.1	2.0	0.6	0.8	-0.5	0.4	1.1	1.2	-0.4	1.7	-0.5	1.8	1.7	2.0	0.3	1.3	-0.4	1.0
Noisy workplace	1.0	1.2	3.0	1.0	0.9	1.5	1.6	0.8	0.7	1.3	1.7	0.2	-0.0	0.9	1.0	1.3	0.2	0.6	-1.7	0.9
Length of working week for main job	1.0	1.1	3.4	1.3	1.0	0.6	0.3	0.6	1.4	0.8	0.1	0.8	1.1	1.6	1.1	0.9	0.8	0.7	1.4	1.8
Qualifications: College or University degree	1.0	3.1	7.9	-1.2	-2.2	-2.0	-2.8	-1.5	-1.7	-2.2	-2.6	-0.1	-1.6	-1.3	-1.5	-1.0	-1.9	-2.0	0.1	-1.6
Leg fat-free mass (right)	1.0	5.2	14.4	2.4	1.9	2.1	0.8	0.0	2.6	1.9	0.6	0.9	3.7	2.7	1.7	1.9	2.5	2.3	3.8	2.9
Mineral and other dietary supplements	1.0	1.3	3.9	1.1	1.3	1.2	0.5	1.0	1.2	1.4	0.5	1.1	1.7	0.8	1.1	1.0	1.5	2.0	-0.6	0.6
Breast cancer (self-reported)	1.0	1.2	4.8	-0.7	-1.1	-1.0	-0.6	-0.9	-1.3	-0.4	-0.2	-0.5	-2.2	-1.2	-0.0	0.3	-1.2	-1.5	-1.4	-1.6
Osteoarthritis (self-reported)	1.0	1.3	3.3	0.9	1.4	1.6	1.2	1.2	1.4	1.8	0.6	0.3	1.0	1.2	1.0	0.6	0.9	1.1	0.3	1.4
Smoking status: Current	1.0	1.6	4.1	1.4	1.5	0.8	0.9	1.1	1.7	1.3	1.1	-0.4	1.5	1.9	0.7	0.6	1.4	0.9	1.4	2.0
Alcohol drinker status: Never	1.0	1.1	3.8	1.0	1.0	1.3	0.8	0.5	1.1	1.1	0.5	0.9	1.2	1.4	0.9	0.8	0.3	0.7	1.4	2.0
Arm predicted mass (left)	1.0	5.1	10.1	2.7	2.4	1.8	1.1	0.6	2.9	1.9	0.9	0.5	3.2	2.9	2.0	2.5	1.9	2.9	3.0	2.5
Reaction Time	0.9	1.7	4.2	2.0	0.9	1.9	-0.0	0.4	1.3	1.6	0.5	0.2	1.4	1.8	2.0	1.9	-0.0	1.0	-0.5	1.1
Supplements: Zinc	0.9	1.0	2.2	1.5	1.1	1.3	0.5	-0.1	1.3	0.9	0.7	0.8	1.3	1.4	0.9	1.1	0.6	0.3	0.5	1.3
Pack years adult smoking proportion	0.9	1.3	2.6	0.9	1.6	0.9	1.4	0.8	1.3	0.9	1.5	0.8	1.5	0.7	1.2	1.2	1.5	1.2	0.2	0.9
Pain all over the body in last month	0.9	1.0	2.9	1.0	0.7	1.3	0.5	1.0	0.9	1.7	0.6	0.6	0.1	1.3	1.0	0.5	1.1	0.5	1.5	1.2
Depression (self-reported)	0.9	1.1	2.8	1.1	0.9	1.1	0.3	0.7	1.2	1.3	0.4	-0.3	0.6	1.3	1.2	1.4	0.8	0.8	1.7	1.4
Ever highly irritable/argumentative for 2 days	0.9	1.0	3.5	0.2	0.5	0.6	1.8	1.3	0.1	1.1	1.9	0.9	-0.9	0.2	0.6	0.6	1.5	1.1	-0.9	0.7
Seen a psychiatrist for nerves, anxiety, tension or depression	0.9	1.2	3.9	1.4	0.9	1.4	0.5	0.9	1.0	2.0	0.6	0.6	0.6	1.4	1.8	1.2	0.9	0.5	0.5	1.0
Health satisfaction	0.9	1.2	5.6	-0.8	-1.0	-0.7	-0.8	-0.6	-0.9	-1.3	-0.9	-2.4	-0.5	-0.7	-1.0	-1.8	-0.3	-1.2	1.2	-0.4
Qualifications: nursing, teaching	0.9	1.5	12.1	1.2	0.1	-0.4	-1.2	-0.8	0.9	0.2	-1.6	0.6	-0.1	1.6	0.5	1.0	0.1	-0.2	3.5	1.1
Basal metabolic rate	0.9	5.0	13.0	2.4	2.1	1.9	1.0	0.4	2.6	2.0	0.9	0.7	3.5	2.6	1.8	2.0	2.3	2.4	3.6	2.7
Average weekly beer plus cider intake	0.9	1.3	3.6	1.4	1.3	1.4	0.6	0.2	1.4	1.8	0.7	0.6	1.9	1.1	1.3	1.3	0.9	1.1	-0.1	0.5
Ovarian Cancer	0.8	1.0	2.5	-1.5	-1.3	-1.2	-0.3	0.0	-1.6	-0.8	-0.2	0.5	-1.6	-1.5	-1.3	-0.9	0.0	-0.3	-0.5	-1.1
HbA1C	0.8	0.9	2.4	-1.3	-0.4	-1.1	-0.0	-0.6	-0.7	-0.7	-0.6	-1.3	0.8	-1.1	-1.5	-1.5	-0.0	-0.7	1.2	-0.7
Medication: Levothyroxine sodium	0.8	1.4	7.6	-1.5	-0.7	-0.7	-0.0	-0.3	-0.7	-0.6	-0.6	-1.8	0.3	-0.9	-1.5	-1.9	-0.2	-1.4	2.8	0.4
Medication: Ventolin 100micrograms inhaler	0.8	1.0	3.8	0.4	-0.8	-0.3	-1.2	-1.4	-0.5	-0.2	-0.8	-0.9	-2.0	0.4	1.0	1.0	-1.9	-0.8	0.1	-0.7
Arm fat-free mass (right)	0.8	4.1	9.7	2.2	2.1	1.7	1.2	0.6	2.5	1.7	1.0	-0.1	3.1	2.3	1.7	2.0	1.9	2.5	2.8	2.4
Wheeze or whistling in the chest in last year	0.8	1.4	4.5	1.4	1.4	1.1	1.2	0.3	1.4	1.2	1.4	-0.9	-0.6	1.4	2.1	1.4	0.6	0.6	-0.0	0.7
Number of children fathered	0.8	0.9	3.2	0.5	1.1	0.7	1.2	0.8	0.8	1.2	0.8	0.4	0.9	0.2	0.9	0.7	1.8	1.6	-0.5	0.7
Arm predicted mass (right)	0.8	3.9	10.0	2.0	2.0	1.5	1.1	0.4	2.4	1.5	0.8	-0.1	3.2	2.3	1.5	1.9	1.9	2.4	3.0	2.4
Supplements: Vitamin C	0.8	0.9	2.9	-1.1	-0.6	-1.5	-0.6	-0.5	-0.5	-1.7	-0.6	-1.1	-0.2	-0.7	-1.7	-1.6	-0.7	-0.5	-0.0	-0.5
Commuting to job workplace: Walk	0.8	0.9	2.7	-1.2	-0.9	-0.6	0.1	-0.2	-1.3	-0.7	0.1	-0.6	-1.3	-1.3	-1.0	-0.7	-0.6	-1.2	-1.6	-0.9
Back pain experienced in last month	0.8	1.2	3.6	-1.6	-0.7	-0.7	0.3	-0.3	-1.2	-0.6	0.1	-1.9	-0.1	-1.7	-1.4	-1.6	-0.6	-1.1	0.7	-1.0
Arm fat-free mass (left)	0.8	4.2	10.0	2.3	2.0	1.6	0.9	0.5	2.5	1.8	0.6	0.2	3.1	2.5	1.7	2.2	1.8	2.5	3.2	2.3
Irritability	0.8	1.4	3.6	0.6	1.2	1.2	1.2	1.3	1.0	1.2	1.2	0.8	1.6	0.4	1.2	0.9	1.9	1.9	-0.1	0.5
Medication: Co-codamol	0.7	0.8	4.3	0.9	-0.0	0.8	-0.2	-0.9	0.6	0.5	-0.5	-1.2	0.5	1.3	0.6	0.2	-0.7	-0.6	2.1	1.4
Supplements: Glucosamine	0.7	0.9	3.2	-0.6	-1.2	0.2	-0.5	-0.7	-1.0	-0.4	-0.4	-0.8	-1.0	-0.6	-0.7	-1.0	-1.3	-1.8	1.5	-0.3
Serious illness, injury or assault of a close relative in last 2 years	0.7	0.8	1.7	1.3	1.0	1.1	0.5	0.7	1.1	0.6	0.5	0.4	1.2	1.2	0.7	1.3	0.0	0.7	-0.0	0.7
Medication: Paracetamol	0.7	1.1	2.0	1.0	1.2	1.4	0.8	-0.0	1.3	1.1	0.6	0.5	1.3	1.3	1.2	1.3	0.6	1.4	-0.1	1.0
Mouth/teeth dental problems: Loose teeth	0.7	0.8	3.6	0.9	0.8	0.9	1.2	0.1	0.4	0.8	1.4	0.2	-0.1	0.4	1.1	1.4	-0.3	-0.1	-1.9	0.5
Number of full sisters	0.7	0.9	1.7	-0.8	-1.2	-1.0	-0.9	-0.7	-1.0	-1.0	-0.7	-1.0	-0.9	-0.8	-0.9	-0.7	-1.2	-1.3	-0.8	-0.6
Whole body fat-free mass	0.7	3.9	11.3	2.1	1.8	1.7	0.8	0.2	2.3	1.6	0.7	0.4	3.1	2.4	1.6	1.8	2.0	2.1	3.4	2.5
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.7	0.8	2.4	0.7	1.0	1.0	1.2	1.0	0.7	0.8	0.9	-0.9	0.7	0.2	0.8	0.8	0.1	1.1	-1.6	-0.1
Whole body water mass	0.7	4.0	11.9	2.1	1.8	1.7	0.8	0.3	2.3	1.7	0.7	0.3	3.2	2.4	1.5	1.8	2.0	2.1	3.5	2.5
Hearing aid user	0.7	0.7	4.6	-0.7	0.4	-0.1	1.5	0.5	-0.3	0.0	1.4	-1.1	-0.7	-0.8	0.0	0.1	-0.3	-0.2	-2.1	-0.4
Fractured/broken bones in last 5 years	0.7	0.9	3.0	-1.1	-0.1	-1.3	0.6	-0.0	-0.5	-0.9	1.2	0.1	0.4	-1.5	-1.1	-0.8	-0.5	-0.3	-1.4	-1.7
Pack years of smoking	0.7	1.1	2.8	0.7	1.5	0.9	1.5	0.7	1.0	0.9	1.7	0.7	1.2	0.3	1.2	1.1	1.4	1.0	-0.1	0.4
Crohns Disease (2017)	0.6	1.4	3.5	1.5	1.2	1.1	0.2	0.9	1.6	1.0	0.9	0.7	0.6	1.7	1.5	1.7	0.4	1.9	-0.3	0.7
Major Depression (MDD)	0.6	0.7	3.9	0.0	0.0	0.0	0.0	0.8	1.9	0.0	0.0	0.0	0.0	2.0	1.3	1.3	0.0	0.0	0.0	0.0
Lupus	0.6	1.0	2.9	-1.2	-0.5	-1.7	-0.5	-1.0	-0.7	-1.2	-0.3	-0.8	-0.6	-1.5	-0.7	-0.7	-0.5	-0.3	-1.5	-1.4
Lung FEV1/FVC ratio	0.6	3.0	5.7	1.7	2.1	1.3	2.2	1.4	1.7	2.2	2.4	1.7	0.7	1.3	1.4	2.4	1.7	2.1	-1.1	0.4
Diabetes (father)	0.6	0.8	3.5	-1.0	-0.6	-1.9	-0.6	-1.0	-0.7	-1.1	-0.6	-0.5	-1.1	-0.9	-0.9	-1.2	-0.3	-0.4	0.5	-0.7
Impedance of leg (right)	0.6	2.8	7.1	-2.1	-1.4	-1.7	0.1	0.9	-2.1	-1.5	0.4	-1.1	-2.7	-2.4	-1.5	-1.5	-1.6	-1.7	-2.1	-1.9
Tinnitus: Yes, but not now, but have in the past	0.6	0.7	2.6	-0.2	0.8	0.3	1.6	1.4	0.4	0.4	1.3	-1.2	-0.0	-0.1	0.0	0.2	0.5	1.4	-0.6	0.4
Serious illness, injury or assault to yourself	0.6	0.7	2.0	0.7	0.9	0.7	0.9	1.1	0.7	0.9	0.8	-0.5	1.0	0.6	0.7	0.7	0.7	1.1	-0.0	1.4
Impedance of leg (left)	0.6	3.1	8.5	-2.1	-1.4	-1.8	0.2	0.6	-2.2	-1.6	0.5	-1.2	-2.9	-2.4	-1.5	-1.5	-1.5	-1.5	-2.5	-1.9
Father’s age at death	0.6	0.8	2.8	1.3	0.7	1.1	0.5	0.3	0.8	0.9	0.6	0.2	0.5	1.0	1.5	1.7	0.0	0.6	0.2	0.7
Pulse wave reflection index	0.6	0.8	2.7	-0.9	-0.9	-0.6	-0.4	-0.6	-0.7	-0.8	-0.2	-0.5	-0.1	-0.4	-1.5	-1.5	0.1	-0.7	1.6	1.2
Blood clot in the leg (DVT)	0.6	0.8	2.9	0.7	0.8	1.1	0.5	0.1	1.0	1.1	0.5	0.2	1.3	0.9	0.5	0.5	1.1	0.1	1.7	0.9
Birth weight	0.6	1.2	3.6	-0.5	-1.2	-1.2	-1.7	-0.8	-0.9	-1.0	-1.9	-1.3	-0.4	-0.4	-0.2	-0.4	-1.6	-1.7	0.7	-0.6
Worry too long after embarrassment	0.6	1.0	2.1	1.0	1.3	1.1	1.0	1.0	1.3	1.0	1.2	0.4	0.3	1.2	1.5	1.0	0.7	0.4	0.9	1.0
Knee pain experienced in last month	0.6	0.9	3.9	0.2	-0.8	-0.3	-1.6	-2.0	-0.3	-0.3	-2.0	-0.6	0.4	0.3	-0.1	-0.3	-0.8	-0.9	1.2	-0.2
Ever had bowel cancer screening	0.6	0.7	3.1	-0.8	-0.5	-0.5	-0.3	-1.3	-0.6	-0.5	-0.5	-1.8	-0.5	-0.8	-0.4	-0.9	-0.5	-1.2	0.2	-0.7
Ever taken oral contraceptive pill	0.6	0.7	2.1	0.8	0.8	0.3	0.2	0.8	0.7	0.7	0.2	1.4	0.7	0.4	1.0	1.0	0.2	1.2	-1.3	-0.9
Financial situation satisfaction	0.6	0.8	2.4	-0.5	-1.1	-0.2	-1.0	-0.8	-0.7	-0.9	-0.9	-1.3	-0.9	-0.0	-0.8	-1.0	-1.6	-1.0	0.5	-0.6
Ever smoked	0.6	1.1	2.4	1.1	1.5	0.8	1.3	0.7	1.3	0.9	1.1	0.1	0.9	0.8	1.0	1.3	0.9	1.0	-1.3	0.9
Depression (Nagel 2018)	0.5	0.7	2.1	1.2	0.5	1.1	0.3	0.6	0.6	0.7	0.8	-1.0	0.5	1.0	1.4	1.4	-0.5	0.4	-0.9	0.3
Ulcerative Colitis (UC)	0.5	1.0	3.6	-0.5	-0.8	-0.3	-0.2	-0.5	-1.0	-1.2	0.2	-1.5	-1.1	-0.9	-0.2	-0.2	-1.9	-0.9	-1.2	-1.7
Verbal and Numeric Reasoning (VNR)	0.5	1.1	5.8	-0.2	0.8	0.6	0.5	1.5	1.0	0.2	-0.0	1.4	2.4	0.5	-0.5	-0.9	1.7	0.9	1.3	0.7
Prostate Cancer	0.5	0.7	2.5	0.7	0.3	0.8	-0.1	0.4	0.7	0.4	-0.3	-0.4	0.8	1.0	-0.1	0.8	0.4	1.5	1.6	1.4
Age at First Birth	0.5	0.7	3.3	0.7	0.6	0.9	0.6	0.6	0.3	0.9	0.1	1.7	0.1	0.2	1.2	0.6	0.2	0.2	-1.8	-0.7
LDL Cholesterol	0.5	0.7	3.5	-0.5	-0.9	-0.8	-0.5	-0.6	-0.8	-0.4	0.1	-1.0	-1.9	0.0	-0.3	-0.1	-0.7	-1.3	-1.1	-1.1
Neuroticism (2016)	0.5	0.7	2.2	-0.4	-1.1	-0.2	-0.3	0.2	-1.2	-0.4	-0.2	-1.0	-1.2	-0.7	0.1	0.1	-1.0	-1.3	-1.5	-1.3
Waist Hip Ratio (WHR)	0.5	2.2	6.1	1.3	1.3	1.5	1.6	1.7	0.7	1.8	2.1	1.0	0.7	0.5	1.9	1.4	1.7	1.6	-2.5	0.0
Hearing difficulty/problems with background noise	0.5	0.9	2.2	1.1	0.3	1.2	-0.9	0.0	0.9	0.7	-0.9	-1.4	0.1	1.3	1.5	1.2	-1.1	0.5	0.4	0.4
Hayfever/allergic rhinitis (self-reported)	0.5	0.6	1.7	1.0	0.5	0.7	-0.4	0.4	0.9	0.5	-0.6	1.1	0.7	1.2	0.9	1.3	-0.1	0.8	0.6	0.6
Medication: Ramipril	0.5	0.6	2.5	0.1	1.0	0.3	1.6	0.6	0.4	0.8	1.5	0.2	0.1	-0.1	0.5	-0.3	1.5	0.1	-0.0	0.6
Fluid intelligence score	0.5	1.0	3.0	0.4	0.7	1.2	0.6	1.2	0.9	1.0	0.5	1.7	1.4	0.9	0.1	0.1	1.7	1.1	1.3	0.5
Hair/balding pattern: Pattern 3	0.5	0.8	2.5	0.3	0.7	1.6	1.2	1.6	0.5	1.0	1.3	0.6	1.1	0.4	0.6	0.2	0.8	0.1	-0.1	1.0
Mouth/teeth dental problems: Dentures	0.5	0.9	9.4	-0.3	-0.9	-0.1	-0.4	-0.8	-0.6	-0.2	0.0	-3.1	-0.5	-0.1	-0.5	-0.7	-1.1	-1.0	0.8	0.4
Hypothyroidism/myxoedema (self-reported)	0.5	0.9	6.9	-1.0	0.0	-0.1	0.8	0.7	-0.2	-0.2	0.0	-1.3	1.1	-0.7	-1.0	-1.2	0.2	-0.4	2.6	0.5
Age at first live birth	0.5	1.0	1.8	-1.1	-1.3	-0.9	-1.3	-1.1	-1.3	-1.3	-1.1	-0.4	-0.5	-1.2	-1.2	-0.9	0.1	-0.3	-0.7	-0.7
Emphysema/chronic bronchitis	0.5	0.6	1.5	-0.7	-0.9	-0.7	-0.5	-0.5	-0.9	-0.5	-0.5	-1.2	-1.2	-0.6	-0.3	-0.8	-0.9	-0.8	-0.4	-0.6
Neck or shoulder pain in last month	0.5	0.7	3.6	-0.6	0.6	0.4	1.7	0.4	-0.0	-0.4	1.9	-1.0	0.3	-0.6	-0.1	-0.5	-0.2	-0.3	-1.3	-0.2
Medication: Omeprazole	0.5	0.6	1.7	0.8	1.1	0.3	0.8	-0.3	1.0	0.5	0.8	-0.7	0.4	0.7	1.2	1.3	0.1	0.7	-0.9	0.2
Illnesses of siblings: Diabetes	0.5	0.6	2.6	-0.7	0.9	-0.0	1.6	0.9	0.3	0.3	1.4	-0.7	0.8	-0.8	-0.4	-0.8	0.5	-0.7	-0.2	-0.3
Average weekly red wine intake	0.5	0.7	1.8	-1.0	-0.8	-1.3	-0.4	0.2	-0.7	-1.2	-0.8	-0.9	-1.0	-0.4	-0.6	-1.1	-1.0	-0.8	0.5	-0.3
Medication: Gliclazide	0.5	0.5	3.2	0.8	0.4	0.6	0.3	0.6	0.6	0.8	0.4	-0.1	0.8	0.6	0.4	-0.1	1.1	-0.3	1.8	0.6
Medication: Paracetamol	0.5	0.7	1.3	0.7	0.9	1.2	0.9	-0.1	0.9	1.1	0.8	0.6	1.0	0.9	0.9	1.0	0.6	1.0	-0.5	0.6
Pain experienced in last month	0.5	0.8	4.2	1.0	0.4	-0.1	-0.1	0.7	0.7	0.2	0.0	2.0	-0.1	0.9	0.6	1.3	-0.1	1.5	-1.6	-0.0
Deep venous thrombosis (DVT) (self-reported)	0.5	0.6	2.2	0.4	0.7	0.9	0.6	0.3	0.7	1.0	0.7	0.3	1.1	0.7	0.2	0.3	1.1	0.1	1.5	1.0
Alcohol drinker status: Previous	0.5	0.6	1.9	0.6	0.6	0.6	1.0	0.9	0.5	0.8	1.1	0.5	0.5	0.3	0.8	0.8	0.4	1.0	-1.4	0.1
Schizophrenia (2018)	0.4	0.9	4.4	0.0	0.0	2.1	0.0	0.0	0.0	0.0	0.0	1.7	0.0	0.0	1.9	2.0	0.0	0.0	0.0	0.0
Respiratory disease	0.4	1.0	3.5	0.0	-0.6	-0.7	-1.4	-1.4	-0.3	-0.5	-1.6	-1.3	-0.9	0.1	0.4	0.1	-1.3	-1.2	1.9	-0.3
Hand grip strength (left)	0.4	0.9	2.6	-1.0	-1.1	-1.2	-1.3	-1.1	-0.9	-1.6	-1.1	-0.0	-0.1	-0.9	-1.2	-0.5	-1.1	-0.4	0.5	-0.9
Frequency of depressed mood in last 2 weeks	0.4	0.6	1.3	0.9	0.7	1.1	0.5	0.5	0.8	0.6	0.8	-0.6	1.1	0.9	1.1	1.1	-0.3	-0.0	0.2	0.6
Frequency of unenthusiasm / disinterest in last 2 weeks	0.4	0.6	1.5	1.0	0.6	0.9	0.0	0.3	0.6	0.7	0.2	-1.0	0.7	0.7	1.2	1.2	-0.5	0.4	-1.2	-0.1
Bilateral oophorectomy (both ovaries removed)	0.4	0.5	1.6	0.2	0.5	0.8	0.6	1.2	0.6	0.5	0.3	0.3	1.0	0.7	0.1	-0.1	0.7	1.3	-0.2	1.1
Sitting height	0.4	2.7	8.9	-1.5	-1.7	-1.5	-1.4	-1.1	-1.3	-1.9	-1.3	-3.0	-0.1	-0.9	-2.0	-2.0	-1.1	-0.5	2.9	0.4
Chronic bronchitis/emphysema (father)	0.4	0.5	2.2	0.1	-0.2	-0.8	-1.2	-1.5	0.3	-0.4	-1.2	-0.8	0.2	0.5	-0.2	0.1	-1.0	-0.1	0.5	0.1
Had other major operations	0.4	0.5	1.4	0.9	0.5	0.4	-0.4	-0.3	0.8	0.3	-0.6	-1.0	0.5	1.1	1.2	1.2	-0.7	-0.4	0.6	0.1
Heart attack	0.4	0.5	2.7	-0.1	0.0	0.1	1.2	0.7	-0.4	0.3	1.6	0.5	-1.2	-0.4	0.1	-0.4	1.2	-0.3	-0.1	0.1
Allergy	0.4	0.9	4.2	-0.8	-0.9	-1.1	-0.1	-0.5	-1.2	-0.9	0.3	-0.0	-1.4	-1.2	-0.9	-0.7	-0.6	0.1	-2.1	-0.9
Trunk fat-free mass	0.4	2.1	7.8	1.5	1.2	1.1	0.5	0.2	1.6	1.0	0.5	-0.2	2.3	1.7	1.1	1.4	1.3	1.5	2.8	1.8
Worrier / anxious feelings	0.4	0.7	2.4	0.7	0.6	0.9	0.7	1.1	0.4	0.9	0.8	-0.9	0.2	0.6	1.6	1.5	-0.2	0.3	-1.1	-0.2
Falls in the last year	0.4	0.5	2.0	-0.3	-0.6	-0.5	-0.2	-1.4	-0.8	0.0	-0.4	-1.2	-0.9	-0.7	-0.1	-0.5	-0.1	-1.4	0.5	-0.5
Medication: Lansoprazole	0.4	0.5	2.2	0.9	0.8	1.0	0.3	0.1	0.6	0.7	0.6	0.1	0.4	0.5	1.1	1.5	-0.3	0.2	-0.7	-0.1
Prospective memory result	0.4	0.4	3.2	-0.5	-0.2	-0.5	0.0	-0.1	-0.4	-0.5	0.0	-1.8	-0.8	-0.3	-0.5	-0.9	-0.5	-1.1	0.3	-0.2
Trunk predicted mass	0.4	2.0	8.0	1.5	1.2	1.1	0.5	0.2	1.6	1.0	0.4	-0.2	2.3	1.7	1.1	1.4	1.3	1.4	2.8	1.8
Standing height	0.4	3.7	8.4	-2.3	-2.4	-1.7	-1.0	-1.2	-2.5	-2.4	-0.6	-2.9	-0.8	-2.2	-2.4	-2.3	-1.4	-2.0	1.4	-0.7
Hair/balding pattern: Pattern 4	0.4	1.0	3.3	-1.5	-0.7	-1.3	-0.5	-0.9	-0.9	-1.2	-0.5	-0.8	-0.3	-1.5	-1.8	-1.4	-0.1	-0.5	-0.0	-0.6
Medication for cholesterol, blood pressure or diabetes	0.4	0.7	2.1	1.1	0.4	1.0	-0.2	-0.1	0.9	0.8	-0.1	0.5	0.9	1.3	0.9	1.4	-0.4	1.0	-0.3	0.8
Medication: Amlodipine	0.4	0.6	3.2	0.7	-0.2	-0.4	-1.3	-1.8	0.2	-0.1	-1.6	-0.4	-0.2	0.8	0.2	0.1	-0.4	-0.1	0.9	0.2
Chronic bronchitis/emphysema (mother)	0.4	0.4	1.3	0.0	0.4	0.9	1.2	0.4	0.2	0.8	1.0	0.3	0.0	0.1	0.3	0.2	1.1	0.4	0.0	1.1
Forced vital capacity (FVC), Best measure	0.4	1.5	3.1	-1.4	-1.7	-1.2	-1.4	-1.0	-1.6	-1.8	-1.3	-0.4	-0.9	-1.4	-1.6	-1.3	-0.9	-0.7	0.3	-1.0
Exposure to tobacco smoke outside home	0.4	0.6	1.6	1.1	0.5	1.0	0.1	-0.3	0.8	0.5	0.1	0.0	1.3	1.0	0.9	1.0	-0.0	0.7	0.5	0.8
Eye problems/disorders: None of the above	0.4	0.5	1.1	0.7	0.5	1.0	0.8	1.0	0.3	0.5	0.7	0.8	0.1	0.4	1.0	0.9	0.5	0.3	-0.9	0.7
Medication: Ibuprofen	0.4	0.4	2.3	0.4	0.5	1.0	0.7	0.4	0.5	0.3	0.7	0.4	0.4	0.4	0.4	0.9	-0.3	0.7	-1.5	-0.1
Medication: Seretide 50 evohaler	0.4	0.5	1.3	0.9	1.1	0.6	0.7	0.3	1.0	0.5	0.7	0.3	0.9	0.7	0.8	1.0	0.1	0.4	-0.0	0.6
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.4	0.5	1.4	-0.6	-0.7	-0.4	-0.5	-1.1	-0.8	-0.7	-0.3	-0.2	-1.2	-0.8	-0.2	0.2	-1.2	-0.6	-1.0	-0.6
Family relationship satisfaction	0.4	0.5	5.6	0.5	-0.1	0.3	-0.3	0.0	0.4	0.4	-0.2	-0.3	0.6	0.8	0.1	-0.2	0.0	-0.6	2.4	1.1
Loneliness, isolation	0.4	0.6	2.2	0.7	0.9	0.5	1.1	0.8	0.5	0.6	1.2	0.7	0.1	0.5	1.1	0.8	0.1	0.2	-1.5	0.2
Mouth/teeth dental problems: Mouth ulcers	0.4	0.6	2.4	1.3	0.5	0.9	-0.1	-0.1	1.0	0.8	-0.2	-0.4	0.5	1.5	0.9	1.1	0.2	1.0	0.2	0.5
Osteoporosis (self-reported)	0.4	0.5	2.5	-0.2	0.2	0.6	1.3	0.9	-0.1	0.1	1.6	-0.7	0.2	-0.3	0.1	-0.9	0.1	-0.7	0.9	0.1
Number of self-reported non-cancer illnesses	0.4	0.7	2.3	0.5	1.3	0.7	0.9	0.6	1.2	0.8	0.3	0.1	1.5	0.7	1.1	0.2	0.6	0.2	0.8	0.8
Guilty feelings	0.4	0.6	1.6	-1.3	-0.1	-0.6	0.9	0.8	-0.5	-0.1	0.8	-0.8	0.2	-1.0	-1.0	-1.0	1.2	-0.5	0.8	0.0
Commuting to job workplace: Public transport	0.4	0.4	0.9	0.8	0.5	0.8	0.5	0.7	0.6	0.8	0.4	-0.1	0.5	0.8	0.8	0.7	0.5	0.1	0.9	0.9
Risk taking	0.4	0.6	1.6	1.0	1.0	0.1	-0.0	0.3	1.3	0.9	-0.1	0.3	0.6	1.2	0.5	1.0	0.5	0.9	0.6	0.8
Ever had prostate specific antigen (PSA) test	0.4	0.5	2.1	-1.0	-0.3	-0.4	0.6	0.4	-0.8	0.2	0.7	-0.6	-0.6	-1.0	-0.9	-0.7	0.7	0.2	-1.5	-0.4
Medication: Omeprazole (e.g. Zanprol)	0.4	0.4	1.0	0.8	0.8	0.0	0.0	-0.7	0.9	0.1	-0.1	-0.9	0.6	0.9	0.9	1.0	-0.1	0.8	-0.7	0.4
Supplements: Calcium	0.4	0.4	2.8	-0.2	0.4	0.2	1.5	0.9	-0.0	0.1	1.7	0.1	0.2	-0.4	0.2	0.5	-0.2	-0.2	-0.4	-0.2
Bipolar Disorder or Schizophrenia	0.3	0.8	3.0	0.0	0.0	1.7	0.0	1.3	0.0	0.0	0.0	1.5	1.5	0.0	1.4	1.3	0.0	0.0	0.0	0.0
Crohns Disease (2012)	0.3	0.4	1.5	0.8	0.5	0.1	-0.0	0.7	0.9	0.6	-0.1	-0.0	0.8	1.0	0.6	0.2	0.5	1.2	0.0	1.0
Triglycerides	0.3	0.5	2.1	0.4	1.0	0.1	0.6	1.1	0.9	0.4	0.9	0.7	0.2	0.0	0.6	0.7	1.4	-0.1	0.2	0.8
Blood Eosinophil Count	0.3	2.5	7.0	1.5	0.3	-0.4	-2.2	-2.5	1.0	0.6	-2.6	1.9	-0.2	2.2	0.7	1.0	1.8	1.9	1.2	1.7
Height	0.3	5.6	10.3	-2.7	-2.9	-2.5	-1.5	-1.7	-2.8	-2.9	-1.3	-2.8	-2.0	-2.4	-2.1	-2.7	-2.8	-3.2	0.9	-1.6
Hypothyroidism (self reported)	0.3	0.7	5.9	-1.1	-0.0	-0.3	0.5	0.5	-0.2	-0.5	0.0	-0.8	0.9	-0.8	-0.7	-1.2	0.2	-0.7	2.4	-0.4
Average weekly spirits intake	0.3	0.3	1.2	0.8	0.6	0.6	0.2	-0.3	0.7	1.1	0.8	-0.4	-0.0	0.8	0.8	0.4	-0.0	-0.1	0.2	0.4
Ever had hysterectomy (womb removed)	0.3	0.3	0.8	-0.3	-0.9	-0.5	-0.8	-0.5	-0.6	-0.4	-0.7	-0.4	-0.1	0.0	-0.6	-0.2	-0.9	-0.5	0.7	0.3
Systolic blood pressure, automated reading	0.3	0.8	3.9	1.1	1.0	0.4	-0.2	-0.2	1.2	0.4	0.0	0.4	0.8	0.9	1.2	0.7	0.8	2.0	-0.9	-0.0
Diabetes (mother)	0.3	0.4	1.1	-0.3	-0.1	-1.1	-0.8	-0.5	0.0	-0.9	-1.0	-0.0	-0.3	-0.2	-0.5	-0.6	-0.8	-0.9	0.2	-0.9
Severe depression (siblings)	0.3	0.3	1.3	0.5	0.5	0.3	0.3	-0.0	0.6	0.7	0.1	-0.1	0.5	0.6	0.3	0.2	0.6	0.3	1.1	0.9
Townsend deprivation index at recruitment	0.3	0.4	1.2	0.8	0.5	1.1	0.2	0.3	0.7	0.6	-0.1	0.6	1.1	0.9	0.4	1.0	-0.3	0.2	0.7	0.5
Maternal smoking around birth	0.3	0.5	1.1	0.7	0.7	0.5	0.4	0.8	0.8	0.7	0.3	0.7	0.7	0.5	0.7	1.0	1.1	0.7	-0.1	0.7
Nervous feelings	0.3	0.6	2.2	-0.9	-1.0	-0.2	-0.2	-0.2	-1.1	-0.4	0.2	-1.0	-0.8	-0.7	-0.6	-1.3	-0.3	-1.5	0.5	-0.2
Forced vital capacity (FVC)	0.3	1.2	2.4	-1.2	-1.5	-0.9	-1.2	-0.8	-1.4	-1.5	-1.1	-0.4	-0.8	-1.2	-1.4	-1.0	-0.9	-0.3	0.4	-1.0
Mouth/teeth dental problems	0.3	0.5	2.5	-0.7	-0.2	-0.8	-0.1	0.5	-0.5	-0.7	-0.6	1.6	-0.6	-0.8	-0.7	-0.9	0.2	0.2	-0.5	-0.7
Medication: Simvastatin	0.3	0.4	2.2	-0.4	-0.3	-0.3	0.3	0.0	-0.7	0.2	0.5	0.4	-0.8	-1.0	0.0	-0.5	0.0	-1.2	-0.7	-1.5
Neuroticism score	0.3	0.6	1.7	0.3	0.8	0.7	0.9	1.3	0.6	0.7	1.1	-0.6	0.7	0.3	1.2	0.5	1.0	0.3	0.5	0.1
Time employed in main current job	0.3	0.3	1.2	0.8	0.4	0.3	0.2	-0.1	0.4	0.8	0.4	0.3	-0.2	0.4	1.0	0.9	0.3	0.6	-1.1	0.0
Medication: Cholesterol lowering	0.3	0.5	1.8	0.0	0.5	0.2	1.0	1.0	0.0	0.6	1.1	1.4	-0.4	-0.4	0.4	-0.4	1.1	-0.6	0.2	-0.7
Exposure to tobacco smoke at home	0.3	0.4	2.2	0.6	0.1	-0.4	-0.0	-0.7	0.2	0.4	0.1	0.3	-1.5	0.7	0.6	0.9	-1.0	-0.4	-0.5	-0.2
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.5	1.3	0.6	1.1	0.7	0.6	0.6	1.1	0.7	0.7	0.3	1.1	0.8	1.0	0.5	0.6	0.4	0.0	0.5
Glaucoma (self-reported)	0.3	0.4	1.1	-0.7	-0.3	-1.1	-1.0	-0.1	-0.2	-0.9	-1.1	0.3	-0.2	-0.3	-1.0	-0.3	-0.3	0.5	-0.4	-0.1
High blood pressure (siblings)	0.3	0.4	1.4	-1.1	0.1	-0.1	0.9	-0.1	-0.5	-0.2	0.8	-0.1	0.8	-1.2	-0.6	-1.0	0.6	-0.4	-0.5	-0.6
Pulse wave peak to peak time	0.3	0.3	1.1	0.0	-0.4	-0.4	-1.0	-0.8	-0.2	-0.4	-0.7	-0.4	-0.3	-0.3	0.3	0.2	-0.8	-0.4	0.2	-1.0
Migraine (self-reported)	0.3	0.3	2.2	-0.1	0.2	0.6	0.5	0.7	-0.0	-0.3	0.6	-0.3	1.1	-0.3	-0.2	0.1	0.4	0.1	-1.5	0.2
Mean time to correctly identify matches	0.3	0.5	1.7	1.0	0.1	1.1	-0.3	-0.3	0.3	0.8	0.1	-1.1	0.0	0.9	1.3	1.1	-0.6	-0.1	-0.5	0.4
Overall health rating	0.3	0.6	4.0	-0.0	0.2	0.4	-0.3	-0.9	0.3	-0.1	-0.7	-2.0	0.6	0.2	0.0	-0.9	0.2	-0.7	1.6	0.4
Had major operations	0.3	0.3	2.0	-0.2	-0.3	-0.5	-0.3	-0.8	-0.3	-0.4	-0.5	-0.4	-0.8	-0.2	-0.5	-1.4	-0.0	-0.5	0.6	0.5
Smoking status: Previous	0.3	0.5	5.0	-0.5	0.0	-0.5	0.1	-0.7	-0.2	-0.6	-0.2	-0.5	-0.1	-0.8	-0.3	0.1	0.1	0.2	-2.2	-0.7
Long-standing illness, disability or infirmity	0.3	0.5	3.0	0.4	0.2	0.8	-0.4	-0.6	0.4	0.3	-0.6	-1.7	0.7	0.7	0.6	-0.1	-0.6	-0.5	1.0	0.5
Friendships satisfaction	0.3	0.3	0.9	0.3	0.6	0.5	0.6	0.6	0.7	0.3	0.5	-0.4	1.0	0.7	0.1	-0.4	0.4	-0.1	0.9	0.8
Asthma (self-reported)	0.3	0.5	1.9	0.8	0.9	0.6	0.4	0.0	0.9	0.6	0.2	-0.3	-0.1	0.9	1.4	1.1	-0.1	0.2	0.7	0.8
Tinnitus: Yes, now most or all of the time	0.3	0.4	1.7	0.1	-0.4	-0.3	-1.3	-1.2	0.1	-0.4	-1.2	0.1	0.3	0.6	0.1	-0.1	-0.6	0.1	0.6	-0.1
High cholesterol (Self-reported)	0.3	0.4	1.6	-0.7	-0.1	-0.4	0.7	0.9	-0.6	-0.1	0.5	1.1	-0.6	-0.8	-0.4	-1.3	0.5	-0.6	0.2	-0.7
Medication: Lisinopril	0.3	0.4	3.4	0.4	-0.1	-0.1	-0.8	-0.2	0.1	0.1	-0.7	1.1	-0.4	0.5	0.6	-0.1	0.6	-0.3	1.8	-0.0
Number of operations (self-reported)	0.3	0.5	1.6	1.1	0.6	0.8	-0.3	-0.4	0.9	0.6	-0.9	-0.2	0.1	1.3	1.2	0.5	-0.4	0.6	0.2	0.3
Myopia	0.3	0.4	2.0	1.0	0.6	1.4	0.4	0.7	0.7	0.4	-0.0	0.2	1.0	1.0	0.7	0.1	0.2	0.1	-0.1	0.4
Heart attack/myocardial infarction (self-reported)	0.3	0.4	1.9	-0.3	-0.2	-0.0	1.0	0.5	-0.6	0.1	1.4	0.2	-1.3	-0.5	-0.1	-0.7	1.1	-0.6	0.0	0.1
Heart disease (siblings)	0.3	0.4	1.8	-0.8	-0.1	-0.3	0.5	-0.3	-0.4	-0.1	0.5	-0.8	0.3	-0.7	-0.9	-1.4	0.9	-0.1	0.3	0.1
Bipolar Disorder (2018)	0.2	0.3	1.4	0.0	0.0	0.0	0.9	0.2	0.8	0.0	0.0	0.6	1.2	0.0	0.4	0.2	0.7	0.4	0.0	0.8
Intelligence (Savage-Jansen 2018)	0.2	0.7	3.7	-0.2	0.7	0.3	0.3	0.9	0.8	0.1	0.1	1.3	1.8	0.2	-0.4	-0.7	1.9	-0.1	0.9	0.3
Irritable Bowel Disease (IBD)	0.2	0.5	1.3	0.9	0.4	0.7	-0.1	0.0	0.6	-0.1	0.5	-0.4	0.0	0.8	1.0	1.1	-1.0	0.7	-1.1	-0.5
Schizophrenia (2014)	0.2	0.4	2.4	0.0	0.0	1.4	0.0	0.0	0.0	0.0	0.0	1.3	0.0	0.0	1.5	1.2	0.0	0.0	0.0	0.0
Systolic Blood Pressure	0.2	0.8	5.1	0.3	0.6	-0.0	0.6	1.3	0.2	0.1	0.8	0.7	0.1	-0.2	0.9	0.3	0.4	1.6	-2.2	-1.1
Allergy or Eczema	0.2	0.6	4.9	0.2	-0.1	-0.5	-1.3	-0.4	0.4	-0.3	-1.7	0.3	0.4	0.5	-0.3	-0.1	0.2	0.0	2.2	0.0
Lung FVC	0.2	0.8	2.0	-0.9	-1.2	-1.4	-1.0	-0.7	-1.0	-0.9	-0.8	-0.6	-1.0	-1.0	-1.2	-0.8	-0.4	-0.5	0.1	-0.5
Neuroticism	0.2	0.4	4.1	-0.5	-0.4	-0.1	0.1	0.3	-0.6	-0.1	0.3	-2.0	-0.5	-0.6	0.3	0.1	-0.2	-1.1	0.3	-0.6
Relative age of first facial hair	0.2	0.5	2.4	-0.3	-0.5	-0.5	-0.8	-0.7	-0.6	-0.8	-0.6	0.2	-0.7	-0.7	-0.3	-0.5	-0.4	-0.1	-1.3	-1.6
Ever used hormone-replacement therapy (HRT)	0.2	0.2	1.9	0.4	-0.1	0.2	-0.2	-0.2	0.0	0.4	-0.1	-1.4	-0.5	0.2	0.3	0.3	-0.7	-0.7	0.1	-0.3
Average weekly fortified wine intake	0.2	0.2	1.0	0.3	0.5	-0.2	0.4	0.6	0.5	0.2	0.3	0.1	0.6	0.4	0.0	-0.2	0.3	-0.1	1.0	0.9
Fed-up feelings	0.2	0.3	0.9	0.4	0.6	0.4	0.5	0.3	0.4	0.3	0.6	-0.6	0.4	0.2	0.9	1.0	0.3	0.7	-0.6	-0.5
Relative age voice broke	0.2	0.3	1.1	-0.5	-0.4	-0.3	-0.3	-0.1	-0.7	-0.9	-0.3	-0.3	-0.4	-0.9	-0.2	-0.4	-0.4	-0.2	-0.7	-1.1
Taking other prescription medications	0.2	0.4	0.9	0.6	1.0	0.4	0.7	0.3	0.7	0.7	0.4	-0.7	0.5	0.3	0.7	0.5	-0.1	-0.4	1.0	0.4
High blood pressure	0.2	0.5	2.4	-0.1	-0.1	-0.4	-0.4	-0.8	-0.4	-0.1	-0.6	0.1	-1.3	-0.4	0.7	0.4	-0.2	-0.3	-1.6	-1.1
Hayfever, allergic rhinitis or eczema	0.2	0.5	4.9	0.2	-0.0	0.1	-0.9	-0.0	0.5	0.1	-1.2	0.0	0.8	0.6	-0.3	-0.1	0.2	0.1	2.2	0.6
Past tobacco smoking	0.2	0.3	3.6	0.1	-0.2	0.4	-0.1	0.6	-0.0	0.3	0.2	0.7	0.2	0.4	0.1	-0.4	-0.2	-0.2	1.9	0.4
Frequency of tenseness / restlessness in last 2 weeks	0.2	0.2	0.8	0.7	-0.2	0.5	-0.4	-0.6	0.3	-0.0	-0.5	-0.4	-0.0	0.9	0.7	0.4	-0.8	-0.1	0.5	0.2
Ever unenthusiastic/disinterested for a whole week	0.2	0.2	0.8	0.0	-0.1	-0.1	0.7	0.7	0.1	0.5	0.8	-0.0	-0.4	0.5	-0.1	-0.1	-0.0	0.9	0.5	0.6
Number of live births	0.2	0.2	0.9	-0.4	-0.1	-0.4	0.4	0.7	-0.3	-0.0	-0.3	-0.6	-0.4	-0.6	-0.1	0.0	-0.8	-0.2	-0.4	-0.9
Happiness	0.2	0.2	0.9	-0.4	0.0	-0.1	0.4	0.5	-0.2	-0.5	0.4	-0.9	0.7	-0.3	-0.7	-0.9	-0.2	-0.1	0.1	0.1
Qualifications: A levels/AS levels or equivalent	0.2	0.4	1.4	-0.7	-0.5	-0.4	-0.7	-0.1	-0.3	-0.9	-1.0	-0.3	0.8	-0.4	-1.2	-0.6	-0.4	0.2	0.9	-0.7
Asthma	0.2	0.3	1.3	0.5	0.7	0.3	0.2	-0.1	0.7	0.3	0.0	-0.3	-0.2	0.7	1.1	0.9	-0.3	0.1	0.9	0.7
Medication: Ibuprofen (e.g. Nurofen)	0.2	0.3	1.9	0.4	0.4	0.6	0.4	-0.0	0.4	-0.1	0.3	0.2	0.5	0.2	0.1	1.0	-0.6	0.3	-1.4	-0.3
Forced expiratory volume in 1-second (FEV1), Best measure	0.2	0.7	1.4	-1.1	-1.1	-0.9	-0.6	-0.2	-1.1	-1.1	-0.6	0.4	-0.7	-1.1	-1.2	-1.0	-0.5	-0.0	-0.0	-0.9
Pulse wave Arterial Stiffness index	0.2	0.2	1.0	-0.1	0.2	0.3	1.0	0.6	0.0	0.2	0.7	0.3	0.1	0.0	-0.4	-0.2	0.7	0.3	-0.5	0.9
Breastfed as a baby	0.2	0.2	1.4	0.4	-0.4	0.6	-0.3	-0.7	-0.1	-0.1	-0.3	-1.2	-0.2	0.5	0.2	0.2	-0.3	0.0	-0.1	0.4
Mouth/teeth dental problems: Bleeding gums	0.2	0.3	0.9	-0.8	-0.5	-0.7	-0.5	-0.4	-0.5	-0.7	-0.1	0.2	0.0	-0.7	-0.6	-0.9	-0.2	-0.9	0.2	-0.5
Number of full brothers	0.2	0.2	1.3	0.1	-0.3	0.5	0.1	-0.4	-0.2	0.7	-0.1	-1.1	0.2	0.2	-0.0	0.7	-0.8	-0.2	-0.4	0.0
Medication: Blood pressure	0.2	0.4	1.0	-0.7	-0.3	-1.0	0.0	-0.6	-0.6	-0.9	-0.1	-0.5	-0.6	-0.8	-0.6	-1.0	0.5	-0.5	-0.0	-0.3
Comparative height size at age 10	0.2	0.8	3.5	-0.7	-0.6	-0.3	0.2	0.0	-0.5	-1.1	-0.1	-1.7	0.7	-0.3	-1.2	-1.2	-0.5	-0.7	1.9	1.0
Leg pain on walking	0.2	0.3	1.1	-0.3	-0.1	0.2	0.8	-0.1	-0.3	0.1	0.5	-0.8	0.0	-0.1	-0.7	-1.0	0.6	0.3	0.1	1.0
Hypertension (Self-reported)	0.2	0.4	2.0	0.7	0.5	0.2	-0.1	-0.4	0.3	0.6	-0.3	0.6	-0.8	0.3	1.4	0.9	0.6	0.5	-1.1	-0.4
Illnesses of father: Heart disease	0.2	0.2	1.6	0.0	0.2	0.4	0.4	0.4	0.3	0.3	0.5	-0.5	0.1	0.3	0.4	-0.5	0.7	-0.3	1.3	0.4
Ever had stillbirth, spontaneous miscarriage or termination	0.2	0.2	1.6	-0.0	-0.0	0.4	0.2	0.3	-0.2	-0.0	0.2	-1.3	-0.3	-0.3	0.1	-0.0	0.6	-0.4	0.5	0.5
Miserableness	0.2	0.3	2.2	-0.6	-0.3	-0.5	-0.3	0.2	-0.3	-0.6	-0.6	-1.5	0.4	-0.5	-0.3	-0.7	0.1	-0.3	0.4	-0.3
Medication: Blood pressure	0.2	0.4	1.6	-0.3	-0.4	-0.5	-0.6	-0.8	-0.6	-0.3	-0.6	-0.4	-1.3	-0.5	0.4	0.1	-0.7	-0.7	-0.7	-1.2
Pain type(s) experienced in last month: Hip pain	0.2	0.2	0.5	0.4	0.5	0.4	0.0	0.3	0.6	0.6	-0.6	0.3	0.6	0.7	0.4	-0.2	0.4	0.1	0.6	0.6
Medication: Atorvastatin	0.2	0.2	0.8	-0.4	-0.3	-0.5	-0.4	-0.3	-0.3	-0.6	-0.9	0.1	-0.2	-0.4	-0.3	-0.9	0.1	-0.6	0.3	-0.7
Diastolic blood pressure, automated reading	0.2	0.7	4.4	0.7	0.7	-0.1	-0.5	-0.4	1.3	0.3	-0.4	0.3	0.9	1.2	0.7	0.6	0.9	2.1	0.6	0.5
Ever depressed for a whole week	0.2	0.3	1.0	-0.4	-0.0	-0.6	0.5	0.1	0.0	-0.3	0.5	-1.0	0.2	0.1	-0.7	-1.0	0.5	0.4	0.6	0.8
Unable to work because of sickness or disability	0.2	0.3	2.3	0.4	0.0	1.5	0.3	0.1	0.0	0.8	0.3	-0.5	0.7	0.3	0.8	0.3	-0.6	0.1	0.0	0.4
Depressed Affect (Nagel 2018)	0.1	0.2	1.6	-0.2	-0.3	-0.2	-0.3	-0.2	-0.3	-0.1	0.1	-1.3	0.1	-0.3	0.1	0.4	-0.4	-0.8	-0.1	-0.5
Neuroticism (Nagel 2018)	0.1	0.1	0.9	-0.2	-0.2	0.2	-0.0	0.4	-0.2	0.1	0.2	-0.9	-0.2	0.1	0.4	0.2	-0.1	-0.6	0.3	0.1
Schizophrenia vs Biploar Disorder	0.1	0.2	1.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.2	1.1	0.0	0.0	0.0	0.0
Worry (Nagel 2018)	0.1	0.3	1.4	-0.4	-0.8	0.2	-0.3	0.5	-0.7	-0.1	-0.3	-0.8	-1.2	-0.2	0.3	0.0	-0.5	-0.9	-0.1	-0.1
Body Mass Index (BMI) (2010)	0.1	0.2	0.5	0.5	0.6	0.3	0.4	0.4	0.7	0.6	0.1	0.7	0.4	0.0	0.7	0.3	0.4	0.3	0.0	0.3
Mean Putamen Volume	0.1	0.1	0.4	0.1	-0.2	-0.6	-0.6	-0.4	0.1	-0.2	-0.3	0.6	0.5	0.3	-0.3	-0.2	0.5	-0.1	0.5	0.4
HDL Cholesterol	0.1	0.2	0.6	0.6	0.3	0.3	0.2	-0.3	0.4	0.2	0.5	0.5	0.3	0.0	0.5	0.7	0.0	0.8	0.4	-0.1
Rheumatoid Arthritis	0.1	0.2	1.5	0.0	0.0	0.4	0.0	-0.4	0.0	0.0	0.0	-1.2	1.0	0.0	-0.3	0.6	-0.0	0.0	0.0	0.0
Type 2 Diabetes (T2D) (2012)	0.1	0.1	1.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.5	0.0	0.0	1.1	0.6	0.0	0.0	0.0	0.0
Ulcerative Colitis	0.1	0.1	1.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.9	1.1	0.0	0.0	0.0	0.0
Smoking Status	0.1	0.3	1.1	0.6	0.5	-0.4	-0.3	-0.5	0.7	0.1	-0.1	-0.7	0.3	0.7	0.0	0.1	0.3	0.7	-1.1	0.2
Hair Pigment	0.1	3.4	8.5	-2.4	-1.9	-2.9	-1.3	-2.2	-2.0	-2.0	-1.2	-1.6	-2.0	-2.0	-2.0	-1.9	-1.3	-0.9	-0.4	-2.0
Tanning	0.1	0.7	3.2	0.7	-0.2	-0.8	-1.8	-0.7	0.6	-0.1	-1.6	0.7	-0.1	1.2	0.2	0.5	-0.6	0.4	1.0	0.8
Number of treatments/medications taken	0.1	0.2	0.8	0.2	0.7	0.4	0.9	0.4	0.4	0.4	0.5	-0.7	0.6	0.1	0.4	0.1	-0.5	-0.4	0.5	0.2
Hand grip strength (right)	0.1	0.2	0.4	-0.2	-0.5	-0.6	-0.6	-0.1	-0.3	-0.6	-0.5	-0.1	-0.5	-0.2	-0.3	0.4	-0.5	0.2	-0.2	-0.6
Frequency of tiredness / lethargy in last 2 weeks	0.1	0.2	1.4	-0.4	-0.1	0.2	0.3	0.1	-0.2	0.2	0.2	-1.2	-0.3	-0.2	0.0	-0.2	0.6	-0.3	0.6	0.2
Forced expiratory volume in 1-second (FEV1)	0.1	0.4	0.9	-0.7	-1.0	-0.5	-0.7	-0.2	-0.9	-0.8	-0.5	0.3	-0.6	-0.8	-0.9	-0.5	-0.6	0.3	0.2	-0.9
Pulse rate	0.1	0.2	0.9	0.5	0.0	0.0	-0.4	-0.7	0.4	0.0	-0.4	-0.8	0.2	0.9	0.3	0.6	-0.1	0.0	0.4	0.2
Tense / ‘highly strung’	0.1	0.2	0.9	0.4	0.1	0.4	-0.1	-0.4	0.2	0.2	0.2	-0.8	-0.8	0.5	1.0	0.5	-0.0	-0.2	0.5	0.5
Birth weight of first child	0.1	0.2	1.6	0.1	0.2	0.1	0.6	0.4	0.2	1.0	0.5	0.2	0.3	0.2	0.3	0.4	0.2	-0.2	1.3	0.5
Peak expiratory flow (PEF)	0.1	0.2	0.4	-0.4	-0.5	-0.3	-0.3	-0.2	-0.6	-0.6	0.1	0.2	-0.3	-0.5	-0.4	0.3	-0.5	0.2	0.4	-0.6
Loud music exposure frequency	0.1	0.1	0.9	0.2	-0.3	0.2	-0.4	0.4	-0.2	0.4	-0.5	1.0	0.0	0.0	0.1	0.2	0.5	0.4	-0.2	0.0
Comparative body size at age 10	0.1	0.4	1.5	0.1	-0.5	-0.5	-0.7	-0.9	-0.3	-0.5	-0.5	-0.9	-0.7	0.0	-0.1	0.2	-0.4	-0.9	1.2	-0.2
Medication for pain relief, constipation, heartburn	0.1	0.2	0.8	-0.1	-0.3	0.2	-0.2	0.9	-0.2	0.0	-0.0	0.9	0.1	0.1	-0.4	-0.3	0.2	0.2	0.8	0.5
Pulse rate, automated reading	0.1	0.4	1.8	0.6	0.1	-0.1	-0.1	-0.4	0.4	0.1	-0.0	-1.3	-0.4	0.9	0.9	1.1	-0.9	-0.6	-0.9	-0.3
Suffer from ‘nerves’	0.1	0.1	0.7	-0.6	-0.6	0.0	0.2	0.4	-0.7	0.1	0.4	-0.2	-0.8	-0.3	-0.3	-0.2	-0.1	-0.1	-0.1	0.2
Chest pain or discomfort	0.1	0.1	0.3	0.5	0.1	0.6	0.3	0.5	0.1	0.2	0.2	-0.3	0.1	0.2	0.5	0.4	0.2	-0.0	-0.4	0.2
Age at last live birth	0.1	0.2	0.6	0.5	-0.1	0.5	-0.6	-0.1	-0.1	0.3	-0.5	0.3	-0.5	0.1	0.4	0.5	0.8	0.8	-0.5	-0.2
Forced expiratory volume in 1-second (FEV1), predicted	0.1	0.1	0.4	-0.6	-0.3	-0.1	0.2	0.1	-0.5	-0.6	0.2	-0.2	0.1	-0.6	-0.3	-0.4	0.3	0.1	-0.1	-0.1
Medication for cholesterol	0.1	0.2	0.5	-0.1	-0.2	-0.4	-0.7	-0.7	0.1	-0.6	-0.4	-0.3	0.6	0.1	-0.4	-0.3	0.2	0.2	0.5	0.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.1	0.1	0.5	0.3	-0.2	-0.0	-0.6	-0.0	0.0	-0.1	-0.7	-0.2	-0.0	0.2	-0.1	-0.2	-0.6	0.5	0.1	-0.4
Wears glasses or contact lenses	0.1	0.1	0.9	-0.1	0.1	-0.2	-0.1	-0.1	0.0	0.4	-0.3	-0.9	0.2	-0.2	0.1	-0.1	0.0	-0.5	-0.3	-0.5
Medication: Bendroflumethiazide	0.1	0.1	0.8	-0.2	-0.0	-0.3	0.1	-0.2	-0.0	-0.1	-0.3	0.0	0.0	-0.0	-0.1	-0.2	-0.0	-0.9	0.9	-0.2
Illnesses of father: High blood pressure	0.1	0.2	0.6	0.1	0.3	0.2	0.2	0.7	0.4	0.2	0.1	-0.0	0.2	0.2	0.4	-0.6	0.7	0.3	0.6	0.3
Vascular/heart problems diagnosed by doctor	0.1	0.4	2.7	0.1	0.0	0.2	0.1	0.7	0.4	0.1	0.2	-0.1	1.2	0.5	-0.7	-0.2	-0.2	0.2	1.6	1.0
Basal cell carcinoma (self-reported)	0.1	0.1	0.7	0.2	0.3	0.2	0.2	-0.0	0.2	0.6	-0.1	-0.1	0.3	-0.1	0.1	0.4	0.8	-0.2	0.1	0.1
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Coronary Artery Disease (CAD)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Cardiovascular Disease	0.0	0.2	0.7	-0.2	0.3	-0.6	0.1	0.6	-0.0	-0.3	-0.2	0.5	-0.5	-0.4	0.3	-0.0	0.0	0.6	-0.1	-0.9
Cholesterol lowering medication	0.0	0.1	0.3	0.0	-0.1	-0.1	0.1	-0.0	-0.3	0.2	-0.1	0.1	-0.5	-0.1	0.0	-0.1	-0.0	-0.4	-0.5	-0.6

Hub : Genes

PLD2

Models

Trait associations