Hub : Genes

PLD6

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1000	0.0370	2.1e-03	0.070	-0.002	0.053	0.067	0.072	7.0e-09	7.0e-01	5.0e-07	1.3e-08	4.2e-09
2	GTEx	Cells EBV-transformed lymphocytes	0.3420	0.1280	1.8e-03	0.037	NA	0.088	NA	0.085	2.3e-02	NA	8.4e-04	NA	1.0e-03
3	GTEx	Heart Left Ventricle	0.0898	0.0393	5.3e-03	0.054	NA	0.029	NA	0.046	7.9e-04	NA	1.1e-02	NA	1.8e-03
4	GTEx	Testis	0.1730	0.0710	3.3e-03	0.067	NA	0.010	NA	0.005	6.7e-04	NA	1.2e-01	NA	1.9e-01
5	NTR	Blood	0.0254	0.0083	2.8e-06	0.021	0.021	0.027	0.024	0.020	1.6e-07	1.8e-07	3.5e-09	3.1e-08	4.5e-07
6	ROSMAP	Brain Pre-frontal Cortex	0.1265	0.0400	8.5e-06	0.010	0.038	0.049	0.048	0.027	1.7e-02	9.4e-06	6.3e-07	8.1e-07	1.9e-04
7	YFS	Blood	0.1063	0.0209	0.0e+00	0.067	0.107	0.104	0.111	0.100	4.7e-21	3.4e-33	4.1e-32	3.0e-34	6.4e-31
8	TCGA	Liver Hepatocellular Carcinoma	0.1150	0.0750	3.6e-03	0.006	0.035	0.078	NA	0.037	1.6e-01	8.8e-03	1.6e-04	NA	7.4e-03
9	TCGA	Soft Tissue Sarcoma	0.1940	0.1230	8.1e-03	0.012	0.023	0.039	NA	0.029	6.3e-02	1.6e-02	2.2e-03	NA	7.3e-03

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Bipolar Disorder (2018)	0.6	0.9	3.2	1.8	0.1	-0.0	-1.6	0.4	-1.1	0.6	0.4	0.8
Bipolar Disorder or Schizophrenia	0.5	1.2	5.7	0.8	-0.4	-0.7	-2.4	-1.4	0.1	-1.4	-0.2	-0.2
Depressed Affect (Nagel 2018)	0.7	1.4	4.1	-0.8	-1.1	-0.7	-2.0	-1.8	1.1	-1.0	-0.4	-1.0
Depression (Nagel 2018)	0.2	0.3	0.8	-0.7	0.9	0.6	-0.1	-0.5	0.6	-0.3	0.1	0.5
Intelligence (Savage-Jansen 2018)	0.3	1.0	4.7	0.6	-0.2	-0.2	1.4	-0.0	2.2	0.7	-1.0	-0.1
Neuroticism (Nagel 2018)	0.4	0.9	1.9	-1.2	-0.8	-0.3	-1.0	-1.4	1.0	-0.5	0.8	-1.2
Schizophrenia (2018)	0.9	1.9	5.2	-0.4	-0.6	-0.9	-1.7	-2.1	1.2	-2.3	-0.3	-1.1
Schizophrenia vs Biploar Disorder	1.2	1.6	7.0	-1.2	-1.0	-0.2	0.6	-0.7	2.6	-1.7	-0.8	-0.6
Worry (Nagel 2018)	0.4	0.9	4.9	-2.2	-0.6	-0.2	0.3	-1.3	0.5	-0.5	0.0	-0.9
Alzheimer’s Disease (in mother)	0.6	0.7	2.6	-1.0	0.7	-0.7	-0.3	0.3	-1.2	0.1	-1.6	-0.2
Alzheimer’s Disease (in father)	1.0	1.1	5.4	-1.1	-0.4	-0.1	-1.1	-0.1	-2.3	-0.9	-0.7	0.9
Alzheimer’s Disease (including proxy)	0.9	1.2	4.9	-1.6	0.3	-0.5	-0.4	0.6	-2.2	0.1	-1.5	0.7
Crohns Disease (2017)	0.9	2.1	5.1	1.6	1.2	-0.2	0.5	2.3	1.4	1.7	2.0	-0.7
Irritable Bowel Disease (IBD)	0.9	2.0	6.8	2.1	1.1	0.0	-0.3	1.9	0.7	1.2	2.6	-0.1
Ulcerative Colitis (UC)	0.5	1.0	4.3	1.4	1.0	0.1	-0.8	0.9	-0.2	0.2	2.1	0.6
Major Depression (MDD)	0.6	0.8	3.2	0.3	-0.3	-0.2	0.6	-0.0	1.7	-0.2	-0.5	-1.8
Reaction Time	0.4	0.8	2.2	0.8	-0.5	-0.7	-1.3	-1.0	0.4	-1.5	0.6	-0.7
Verbal and Numeric Reasoning (VNR)	0.3	0.7	2.5	-0.2	-0.2	-0.7	1.6	1.1	1.0	0.4	-0.9	0.1
Breast Cancer	0.3	0.8	2.1	1.1	0.4	1.2	-0.2	0.7	-1.0	0.3	0.7	1.4
Ovarian Cancer	2.5	3.3	8.7	-0.3	0.4	3.0	1.8	2.1	-2.0	1.8	0.2	2.4
Prostate Cancer	0.7	0.9	2.5	-1.4	-0.2	1.3	-0.4	-1.6	0.1	-1.4	-0.3	0.3
Age at First Birth	0.4	0.5	1.7	0.1	0.9	1.0	0.2	-0.0	-0.9	-0.3	1.3	0.4
Bipolar Disorder (2011)	0.4	0.4	3.7	0.0	0.0	0.0	0.0	0.0	0.0	1.9	-0.1	0.2
Body Mass Index (BMI) (2010)	0.8	1.1	2.7	0.3	-1.0	-1.5	-0.0	1.0	-1.0	1.6	-1.3	0.5
Coronary Artery Disease (CAD)	2.1	2.5	6.4	0.4	-1.9	-2.5	-2.2	-1.8	-0.7	-1.0	-0.3	-1.6
Crohns Disease (2012)	1.2	2.0	5.6	2.4	1.2	0.7	-0.3	1.7	-0.1	1.4	2.3	0.5
Mean Putamen Volume	1.2	1.4	4.4	1.8	0.7	0.1	0.8	2.1	-0.8	1.1	1.0	0.9
Fasting Glucose	0.3	0.4	1.5	-1.2	0.2	-1.1	-0.1	0.1	-0.6	-0.0	-0.6	-0.0
HbA1C	0.7	0.8	3.9	-1.2	-0.2	0.5	2.0	0.8	0.4	0.8	0.3	-0.5
HDL Cholesterol	0.4	0.7	2.0	-0.1	1.4	1.2	1.1	0.7	-0.1	0.2	0.6	0.6
LDL Cholesterol	0.7	1.1	2.7	-0.7	-1.2	-0.2	1.6	0.2	1.3	0.7	-0.8	-1.5
Lupus	0.7	1.0	3.7	-0.9	-0.6	-1.9	-0.1	0.7	-0.6	0.3	-1.2	-1.4
Neuroticism (2016)	0.8	1.1	2.9	0.2	-1.7	-0.6	-1.4	-0.9	1.1	-0.5	0.6	-1.5
Primary Biliary Cirrhosis	0.2	0.2	0.8	0.0	-0.9	0.1	0.5	0.6	0.7	-0.0	0.4	-0.6
Rheumatoid Arthritis	0.2	0.3	0.6	0.7	0.6	0.8	-0.2	0.3	0.4	-0.3	0.7	0.2
Schizophrenia (2014)	1.0	2.3	5.2	-1.1	-0.3	-1.5	-1.6	-1.8	1.4	-2.3	0.2	-2.0
Triglycerides	0.3	0.5	2.1	-0.3	-1.0	-0.3	0.3	0.5	-1.4	0.5	-0.4	0.5
Type 2 Diabetes (T2D) (2012)	1.0	1.2	3.5	1.1	-0.2	0.4	0.9	1.1	-0.7	1.9	0.0	1.8
Ulcerative Colitis	1.0	1.4	4.3	2.0	-0.1	0.7	0.1	1.6	-0.1	1.1	2.1	0.6
Blood Eosinophil Count	0.1	0.8	2.8	-0.4	-1.7	-0.2	0.1	0.7	1.3	1.2	0.5	-0.1
Blood Platelet Count	0.3	3.8	17.5	0.8	0.4	2.2	0.6	1.4	1.1	1.2	4.2	2.5
Blood Red Count	0.4	3.6	14.5	-1.9	0.4	1.8	0.1	-3.8	1.4	-2.9	0.1	0.8
Blood White Count	0.4	2.6	9.4	-1.2	-1.3	1.6	1.9	0.3	3.1	1.0	1.9	-0.3
Heel T-Score	2.2	17.8	44.0	1.9	2.7	4.8	3.9	4.8	-3.2	4.6	3.5	6.6
BMI	0.3	1.7	4.6	-0.9	0.3	-1.4	-1.8	-2.0	-0.7	-2.1	-0.0	-0.4
Height	0.1	2.3	12.2	0.4	-0.4	0.4	0.9	-0.5	3.5	-1.2	-2.3	-0.3
Waist Hip Ratio (WHR)	1.6	7.0	22.8	-2.0	-3.8	-2.4	1.3	0.4	3.2	1.9	-0.5	-4.8
Systolic Blood Pressure	0.8	3.8	8.9	0.9	-1.1	2.5	3.0	2.7	-1.0	2.5	1.4	0.3
Smoking Status	0.9	2.2	5.9	0.4	1.6	-0.4	-0.8	1.8	-2.4	2.3	-0.8	1.0
Allergy or Eczema	0.3	0.9	3.7	-1.9	-1.1	0.4	1.2	-0.3	-0.6	0.7	-0.5	-0.1
Cardiovascular Disease	0.7	2.3	6.2	0.1	-1.2	1.4	2.5	1.9	1.1	2.0	1.3	-0.7
Hypothyroidism (self reported)	0.8	1.8	6.0	-0.5	-2.5	-0.0	1.6	-0.0	2.3	0.2	-1.5	-0.1
Respiratory disease	0.7	1.5	5.1	-0.9	0.0	-2.3	-1.4	-1.6	-0.4	-0.7	-1.3	-1.0
Type 2 Diabetes (T2D) (2018)	0.2	0.4	0.8	-0.7	-0.6	0.6	-0.3	-0.9	0.0	-0.8	-0.1	0.8
Lung FEV1/FVC ratio	1.0	4.9	17.7	-0.6	-4.2	-0.6	0.2	-1.2	3.6	0.4	-2.1	-2.6
Lung FVC	0.6	2.8	8.1	0.1	-0.9	0.5	2.5	2.8	-1.1	2.4	-0.6	1.8
Neuroticism	0.2	0.5	1.7	-1.1	-1.3	0.3	-0.0	-0.2	0.7	0.2	0.6	-0.6
Chronotype (morning person)	0.6	1.3	5.9	1.0	2.4	-0.1	0.2	0.2	0.5	0.3	2.1	-0.6
Hair Pigment	0.1	3.0	8.5	0.6	-1.1	-1.1	-2.9	-2.1	-1.2	-2.1	-2.5	0.3
Tanning	0.1	1.5	3.4	-1.3	1.6	0.6	0.0	-0.2	-1.4	-0.7	-1.8	1.9
Hand grip strength (left)	1.0	2.7	7.6	-2.6	-2.2	-1.0	1.4	-0.7	0.9	0.2	-2.8	-0.3
Number of treatments/medications taken	0.2	0.3	1.2	-1.1	-0.5	-0.7	0.6	-0.1	0.4	0.2	-0.4	-0.5
Average weekly spirits intake	1.0	1.3	3.7	-1.9	-1.0	-0.5	-0.6	-1.4	-1.0	-1.1	-1.3	-0.0
Sensitivity / hurt feelings	0.2	0.4	1.0	-0.6	-0.9	0.3	-0.4	-0.1	0.8	1.0	0.8	0.3
Frequency of depressed mood in last 2 weeks	0.5	0.7	2.5	-0.6	0.8	0.5	-1.6	-1.2	-0.1	-0.5	-0.5	1.1
Hearing difficulty/problems: Yes	0.1	0.1	0.3	-0.5	0.2	-0.3	0.2	-0.3	-0.1	-0.1	0.1	-0.4
Relative age of first facial hair	0.2	0.3	0.9	-0.7	-1.0	-0.0	0.3	0.3	0.0	0.8	0.6	-0.5
Other serious medical condition/disability diagnosed by doctor	2.0	2.6	9.3	-1.5	0.3	-0.7	-1.4	-3.0	1.0	-2.5	-1.3	-0.7
Ever used hormone-replacement therapy (HRT)	0.5	0.6	1.8	1.3	0.9	1.3	-0.1	0.2	-0.5	-0.3	0.0	0.9
Ever had hysterectomy (womb removed)	0.4	0.5	2.2	0.7	-1.5	-0.2	0.4	-0.1	0.9	0.8	0.2	-0.1
Systolic blood pressure, automated reading	0.3	1.0	2.9	0.8	-0.7	1.7	1.7	0.8	-0.8	0.6	0.3	-0.0
Eye problems/disorders: Diabetes related eye disease	3.7	4.0	9.0	-0.5	-1.6	-2.7	-3.0	-2.6	0.2	-2.2	-2.1	-1.1
Angina	0.8	1.0	3.2	-0.6	-1.8	-1.0	-1.4	-0.8	0.1	-1.3	0.4	0.3
Medication for hormone replacement therapy	1.9	2.1	5.7	0.8	1.6	2.0	1.9	1.2	-0.0	1.0	-0.3	2.4
Vitamin and mineral supplements	0.4	0.5	1.2	-0.7	0.3	-0.8	-0.3	-1.1	1.0	-0.8	-0.5	0.2
Supplements: Zinc	0.7	0.8	2.2	0.7	0.0	-1.4	-0.4	0.5	-0.5	1.5	0.3	-1.3
Medication: Co-codamol	1.0	1.1	5.9	0.1	0.2	0.3	-1.1	-1.5	-0.0	-2.4	0.6	-0.2
Medication: Metformin	0.3	0.4	1.5	-0.8	-1.2	0.5	0.0	-0.6	-0.3	-0.3	-0.7	0.8
Diabetes (father)	0.7	0.9	2.7	-1.7	-0.2	0.3	0.9	-0.4	1.6	-1.2	-0.6	-0.1
Diabetes (mother)	0.6	0.7	2.5	1.4	-0.2	0.8	0.2	0.7	0.5	0.7	1.6	0.3
Severe depression (siblings)	1.2	1.3	3.4	1.4	-0.3	0.2	1.1	1.8	1.2	1.9	0.5	0.3
Pack years adult smoking proportion	0.4	0.6	1.7	0.6	0.8	0.2	-1.3	-0.2	-0.1	-0.8	1.3	-0.5
Impedance of leg (right)	0.7	3.5	8.0	2.0	-2.8	-1.4	1.0	1.5	1.2	2.7	-1.5	-1.9
Leg fat-free mass (left)	0.3	1.5	3.8	-1.9	1.5	-0.7	-0.6	-1.4	1.0	-1.9	-0.2	-0.6
Trunk fat percentage	0.3	1.3	3.9	-0.5	-0.8	-2.0	-0.1	-0.9	1.2	-1.3	0.0	-1.7
Hand grip strength (right)	1.1	2.9	7.6	-2.7	-1.8	-1.1	1.8	-0.7	1.3	0.8	-2.8	-1.0
Townsend deprivation index at recruitment	0.5	0.7	2.8	-1.1	0.8	1.7	1.0	-0.1	-0.9	-0.4	0.0	0.3
Current tobacco smoking	0.7	1.1	3.1	-0.6	0.8	0.2	-1.6	-0.0	-1.8	-0.6	-1.5	0.9
Average weekly fortified wine intake	0.3	0.4	1.8	-0.1	-1.4	0.1	-0.1	-0.0	-0.4	-0.3	0.5	-1.1
Maternal smoking around birth	0.6	0.9	2.0	1.0	-1.0	-1.0	-0.1	0.7	1.0	0.7	0.8	-1.4
Fed-up feelings	0.7	1.3	4.6	-0.2	-2.1	-0.3	0.1	0.5	1.9	1.6	0.9	0.1
Frequency of unenthusiasm / disinterest in last 2 weeks	0.4	0.5	3.0	-1.7	0.7	0.7	-0.3	-0.4	0.1	-0.2	0.1	0.7
Relative age voice broke	0.3	0.4	1.6	-1.3	0.5	0.2	0.6	0.4	-1.0	0.4	-0.6	-0.2
Taking other prescription medications	0.7	1.1	6.2	0.5	-0.6	-0.4	1.1	0.5	2.5	0.6	0.2	-0.8
Age when periods started (menarche)	0.5	1.1	4.3	-2.1	-1.5	0.5	1.2	0.9	0.4	1.0	0.3	0.2
Bilateral oophorectomy (both ovaries removed)	0.6	0.7	1.6	-1.2	0.7	0.8	0.6	-0.1	1.2	-0.7	-1.1	-0.2
Heel bone mineral density (BMD) T-score, automated (left)	1.4	3.2	8.4	-0.4	0.8	2.2	2.9	1.5	0.2	2.8	0.8	2.1
Tinnitus: Yes, but not now, but have in the past	2.5	2.7	8.7	-0.3	1.4	0.7	2.4	2.4	-0.3	3.0	-0.8	0.7
Qualifications: CSEs or equivalent	0.3	0.4	1.3	-1.2	0.1	0.3	0.5	0.8	0.2	0.9	0.5	-0.3
Serious illness, injury or assault to yourself	0.8	0.9	2.3	-1.5	-0.8	-1.2	-1.0	-0.5	-0.5	0.1	-1.4	-0.5
High blood pressure	0.4	1.0	2.7	0.6	-0.8	0.6	1.6	1.5	-0.2	1.4	1.1	-0.4
Hayfever, allergic rhinitis or eczema	0.3	0.6	1.6	0.4	-0.7	0.9	1.1	0.1	-0.2	1.3	0.5	0.6
Multivitamins +/- minerals	0.9	1.1	2.6	1.1	0.1	1.5	1.2	1.0	-0.6	1.6	1.0	0.5
Stomach or abdominal pain in last month	0.8	0.9	2.8	-0.2	0.5	-0.1	0.9	0.3	1.6	0.7	1.7	-1.2
Supplements: Glucosamine	1.1	1.4	3.3	0.2	0.6	-1.4	-1.4	-1.0	-1.0	-1.7	-1.8	0.4
Diverticular disease/diverticulitis (self-reported)	1.3	1.6	3.6	-1.0	-1.6	-1.9	-0.2	-0.5	1.3	0.2	-1.3	-1.9
Medication: Atenolol	0.8	1.0	2.8	-1.4	-1.6	-0.3	1.2	0.1	0.1	0.3	-0.1	-1.7
Medication: Levothyroxine sodium	0.4	0.6	3.0	-0.6	-1.7	-0.2	0.6	0.4	0.8	0.1	-1.0	-0.0
Sitting height	0.4	2.7	7.8	-0.7	0.7	-1.4	-1.1	-1.9	2.8	-1.3	-2.4	-1.0
Chronic bronchitis/emphysema (father)	1.0	1.2	1.9	-1.4	-1.3	-0.9	1.3	1.0	-0.1	1.2	0.9	-1.1
High blood pressure (mother)	0.3	0.4	2.0	0.0	-1.0	-0.2	0.1	0.7	0.1	1.4	0.1	-0.3
Body mass index (BMI)	0.3	1.3	4.5	-1.1	0.4	-1.1	-1.1	-1.8	0.1	-2.1	-0.2	-0.4
Impedance of leg (left)	0.7	3.2	9.3	2.6	-3.0	-1.0	0.7	1.3	0.9	2.3	-1.3	-1.3
Leg predicted mass (left)	0.3	1.6	3.8	-1.9	1.4	-0.8	-0.7	-1.4	1.1	-1.9	-0.2	-0.7
Trunk fat mass	0.3	1.5	3.8	-1.0	-0.3	-1.9	-0.3	-1.2	1.3	-1.6	-0.4	-1.7
Waist circumference	1.2	4.5	9.3	-2.1	-1.0	-2.7	-1.4	-2.6	1.2	-2.3	-1.8	-3.1
Number of incorrect matches in round	0.9	1.6	7.5	-0.8	0.3	0.5	-0.1	0.7	-2.7	-0.2	-1.0	2.0
Past tobacco smoking	1.4	2.5	6.3	-1.1	-0.1	1.0	0.7	-2.4	2.4	-2.5	1.1	-0.6
Alcohol usually taken with meals	0.5	0.8	2.8	0.5	-1.0	-0.9	0.4	0.7	0.5	0.7	-1.7	-0.7
Nervous feelings	0.3	0.5	2.0	-1.4	-0.3	-0.1	0.8	-0.7	1.1	0.4	-0.1	-0.4
Frequency of tenseness / restlessness in last 2 weeks	0.8	1.3	4.0	-1.5	-0.4	-0.1	-2.0	-1.7	-0.0	-0.8	-1.3	0.3
Hearing difficulty/problems with background noise	0.7	1.0	3.3	-0.3	-0.7	0.7	1.1	1.6	0.1	1.1	1.8	-0.3
Hair/balding pattern: Pattern 2	1.1	1.4	4.6	0.7	-0.9	-0.7	-1.6	-2.1	0.4	-1.6	-1.0	0.1
Had menopause	0.8	1.0	3.5	1.9	0.9	-0.9	-0.7	0.3	-1.6	-0.1	0.0	-0.5
Had other major operations	1.4	1.7	5.5	2.4	-0.6	-0.9	-1.6	-0.5	-0.1	-0.6	1.6	-1.8
Forced vital capacity (FVC)	0.7	2.6	8.2	-1.0	0.4	1.0	2.9	2.1	0.3	2.1	-1.6	1.4
Heel bone mineral density (BMD) T-score, automated (right)	1.2	2.8	6.9	0.5	0.8	2.0	2.6	1.4	0.3	2.5	1.7	1.4
Ever unenthusiastic/disinterested for a whole week	0.7	0.9	3.1	0.3	1.8	-1.0	-1.3	-0.9	-0.0	0.2	0.7	-0.8
Qualifications: None of the above	0.5	1.1	2.4	1.4	0.7	0.2	0.7	1.2	0.7	1.5	1.5	-0.5
Financial difficulties in last 2 years	1.1	1.5	3.2	-0.9	0.1	1.1	1.8	1.3	0.9	1.6	-1.2	1.3
Mouth/teeth dental problems	1.2	1.8	5.8	0.9	0.5	1.7	1.1	1.4	-1.4	1.2	0.0	2.4
Heart attack	0.3	0.4	1.5	-0.1	-0.6	-0.1	0.6	0.4	1.0	0.5	1.2	0.0
Allergy	0.2	0.5	2.1	0.2	-0.7	-0.6	-0.8	-0.2	0.3	-0.9	-0.1	-1.4
Pain all over the body in last month	0.7	0.8	1.6	0.6	0.1	0.5	-1.2	-1.2	-0.8	-0.8	-0.8	1.3
Diabetes (self-reported)	0.6	0.9	2.1	-1.3	-0.1	0.3	-0.6	-0.8	-1.0	-0.6	-1.4	1.3
Hayfever/allergic rhinitis (self-reported)	1.1	1.4	4.3	-1.1	-1.5	-0.5	-0.3	-2.1	0.7	-1.3	-0.6	-1.3
Medication: Ramipril	1.6	2.1	6.3	-1.0	-1.8	1.7	2.5	1.1	1.2	0.8	1.4	0.0
Medication: Simvastatin	0.6	0.9	2.4	0.8	-1.6	-0.2	0.9	1.2	0.4	1.4	-0.1	-1.0
Fluid intelligence score	0.3	0.7	1.8	0.6	0.6	0.4	0.6	0.6	-1.2	-0.1	-1.1	1.3
Illnesses of siblings	0.6	0.9	3.9	0.4	-1.2	-0.8	0.1	-0.0	2.0	0.1	0.5	-1.3
Neuroticism score	0.5	1.0	2.8	-1.7	-1.2	-0.1	0.0	-0.3	1.7	0.8	0.6	-0.8
Weight	0.4	1.8	4.3	-1.3	0.7	-1.4	-0.9	-1.8	1.0	-2.1	-1.2	-0.9
Impedance of arm (right)	0.6	2.6	6.9	1.8	0.2	0.1	1.8	2.6	0.3	2.4	1.7	-0.8
Arm fat percentage (right)	0.2	0.8	2.6	-0.7	0.7	-1.1	-0.6	-1.1	0.2	-1.6	0.7	-0.8
Trunk fat-free mass	0.4	2.2	4.2	-1.5	1.2	-1.1	-1.6	-1.9	1.0	-2.0	-1.7	-0.9
Hip circumference	0.4	1.7	7.1	-0.9	1.5	-0.2	-0.8	-1.9	0.0	-2.7	-1.0	0.6
Time employed in main current job	0.4	0.4	1.3	-0.5	-0.7	-0.2	1.0	-0.1	0.2	0.8	-1.1	-0.0
Alcohol intake versus 10 years previously	1.5	2.2	8.4	-2.9	-0.9	-1.5	-0.6	-0.9	1.7	-0.8	-0.9	-1.7
Father’s age at death	2.7	3.6	9.3	-1.0	-0.1	-1.8	-2.1	-2.1	-0.7	-3.0	-2.6	-1.6
Worrier / anxious feelings	1.2	2.3	6.1	-2.1	-0.5	-1.0	-1.6	-2.5	0.7	-2.2	0.2	-1.0
Frequency of tiredness / lethargy in last 2 weeks	0.6	0.9	2.7	-1.6	0.3	0.8	1.2	0.2	0.9	1.4	0.7	-0.3
Falls in the last year	0.7	0.9	2.4	-0.4	0.3	-0.7	-1.4	-0.4	-1.2	-0.6	-1.2	1.5
Hair/balding pattern: Pattern 3	0.7	1.1	3.6	-0.6	-0.9	0.6	1.9	1.2	1.1	1.3	-0.1	-0.0
Number of live births	1.4	2.0	6.6	0.1	1.3	1.2	2.6	1.9	0.9	1.7	1.2	0.1
Forced expiratory volume in 1-second (FEV1)	0.6	1.9	6.2	-0.7	-0.6	1.1	2.5	1.3	1.3	1.7	-1.7	0.4
Pulse rate	2.4	4.0	9.4	-0.1	-0.6	-1.4	-2.1	-2.9	1.7	-2.9	-3.1	-0.3
Happiness	1.5	1.8	10.7	-0.5	-1.7	-0.8	0.4	0.5	3.3	0.5	-0.3	-1.1
Noisy workplace	1.0	1.3	2.9	0.7	1.7	1.7	-0.2	-0.4	0.9	-0.3	1.7	1.0
Qualifications: A levels/AS levels or equivalent	0.4	0.9	3.1	-1.6	-0.9	-0.7	-0.1	-0.7	0.3	-0.5	-1.8	-0.0
Serious illness, injury or assault of a close relative in last 2 years	1.0	1.2	5.6	0.5	-1.4	-0.8	-0.3	1.2	0.4	2.4	0.3	-0.7
Mouth/teeth dental problems: Dentures	1.6	2.6	6.0	-0.2	-0.4	-1.9	-1.8	-2.1	1.6	-1.8	-0.4	-2.5
Asthma	0.2	0.4	0.9	0.1	0.8	-0.7	-0.5	-0.9	-0.1	0.0	-0.9	0.3
Medication: Ibuprofen (e.g. Nurofen)	0.6	0.8	4.0	-0.7	-2.0	-1.0	-0.9	-0.6	0.1	0.2	-0.3	0.2
Medication: Cholesterol lowering	0.5	0.8	3.5	-0.9	-1.9	-0.3	1.0	0.5	0.1	1.0	-0.9	0.1
Depression (self-reported)	0.4	0.5	2.6	-0.4	0.4	0.2	0.4	0.2	1.6	-0.0	-0.2	1.0
Medication: Lansoprazole	1.7	1.9	5.4	0.6	-2.3	-2.3	-1.2	0.2	0.2	-0.2	0.2	-2.2
Prospective memory result	0.8	1.0	6.8	0.3	0.1	-0.2	0.1	1.0	-2.6	0.7	0.8	0.2
Lung cancer (father)	0.9	1.1	4.1	1.7	0.1	0.5	-0.4	0.1	-2.0	0.9	1.0	0.8
Illnesses of mother	0.5	0.6	2.0	-0.2	1.4	0.8	0.2	-0.9	-0.3	-0.7	-0.4	1.0
Forced expiratory volume in 1-second (FEV1), Best measure	0.9	2.9	9.5	-0.8	-0.6	1.6	3.1	1.4	1.4	2.1	-1.4	1.6
Pulse wave Arterial Stiffness index	2.3	2.7	5.4	1.7	1.2	0.6	-2.3	-2.1	-1.2	-2.2	-0.0	1.9
Impedance of arm (left)	0.7	3.2	9.0	2.0	-0.1	0.0	2.1	3.0	0.4	2.7	2.0	-0.6
Arm fat mass (right)	0.3	1.4	4.0	-1.0	0.5	-1.5	-1.1	-1.5	0.7	-2.0	-0.2	-0.9
Trunk predicted mass	0.4	2.3	4.2	-1.5	1.2	-1.2	-1.7	-1.9	0.9	-2.1	-1.7	-0.9
Standing height	0.2	1.7	7.1	-0.7	0.6	-1.1	0.1	-0.2	2.0	-0.1	-2.7	-1.2
Length of working week for main job	0.9	1.0	4.2	0.7	-0.1	-1.0	-2.0	-1.1	-0.8	-1.2	0.4	-0.5
Exposure to tobacco smoke at home	0.4	0.4	1.6	-0.6	0.3	0.2	1.3	0.9	-0.3	0.9	0.1	-0.4
Breastfed as a baby	0.4	0.5	1.6	0.7	-1.2	-0.3	-0.3	0.3	0.6	0.8	-0.1	-1.3
Tense / ‘highly strung’	0.3	0.4	1.9	-0.7	-1.0	0.0	-0.3	-1.4	0.3	-0.3	-0.1	0.1
Seen doctor (GP) for nerves, anxiety, tension or depression	0.6	0.9	3.2	0.2	0.6	-0.9	-1.0	-1.1	1.8	-0.7	-0.3	-0.7
Hair/balding pattern: Pattern 4	0.7	1.8	4.1	-0.1	1.7	1.8	2.0	1.3	-0.9	1.0	0.3	1.4
Birth weight of first child	0.3	0.6	1.3	0.7	-0.1	0.5	-0.9	-1.0	-0.4	-0.4	-0.8	1.1
Peak expiratory flow (PEF)	0.6	1.4	3.2	-1.3	-1.8	-0.0	0.5	-1.0	1.8	-0.7	-1.3	-1.2
Pulse wave reflection index	2.4	3.0	9.0	0.9	2.5	2.2	0.4	0.3	-1.6	-0.1	1.7	3.0
Ever highly irritable/argumentative for 2 days	0.7	0.9	2.0	0.4	1.4	1.2	-0.4	-0.0	-0.5	0.5	1.2	1.4
Loud music exposure frequency	1.1	1.2	4.2	2.1	-0.3	0.2	-1.2	1.1	-1.1	-0.1	1.4	0.8
Qualifications: O levels/GCSEs or equivalent	1.6	2.5	7.4	-2.3	-1.7	-1.5	-0.7	-1.2	0.8	-1.1	-2.7	-1.2
Mouth/teeth dental problems: Bleeding gums	0.5	0.7	2.1	0.8	0.1	0.4	0.8	1.4	0.5	1.1	0.9	-0.1
Blood clot in the leg (DVT)	0.7	0.9	2.9	-1.7	-0.1	-1.4	-0.7	-0.5	0.3	-0.7	-1.3	0.3
Medication: Paracetamol	0.4	0.7	2.3	-0.3	0.8	0.5	-0.9	-1.5	-0.6	-0.9	-0.4	1.0
Headache pain in last month	0.6	1.0	5.8	-0.4	-0.8	-0.2	0.6	-0.2	2.4	0.1	-0.2	-1.2
Medication for cholesterol, blood pressure or diabetes	0.3	0.5	2.5	0.7	1.6	-0.1	-0.9	-0.7	0.6	-0.5	-0.1	-0.0
Glaucoma (self-reported)	0.4	0.4	1.2	0.8	-0.4	0.1	0.9	1.1	0.3	1.0	0.1	-0.0
Gout (self-reported)	0.6	0.8	4.0	-2.0	0.0	-1.3	-0.3	-0.4	-0.8	-0.8	-0.4	-0.2
Hypothyroidism/myxoedema (self-reported)	0.5	0.9	3.0	-0.7	-1.7	-0.5	0.7	-0.5	1.6	-0.3	-1.2	-0.1
Medication: Amlodipine	0.4	0.5	2.2	-0.8	0.8	-0.3	0.2	-0.6	-1.5	-0.5	0.7	-0.3
Medication: Ventolin 100micrograms inhaler	0.6	0.8	2.3	0.2	1.5	-0.2	-0.9	-0.9	-1.5	-0.2	-0.0	0.7
Birth weight	0.2	0.5	1.8	0.0	1.3	-1.0	-1.0	-0.7	0.3	-0.5	0.3	-0.3
Chronic bronchitis/emphysema (mother)	0.4	0.5	3.2	0.0	1.8	0.5	0.2	-0.1	-0.5	-0.3	0.2	0.8
High blood pressure (siblings)	0.7	1.0	4.3	0.2	0.2	-0.6	0.0	1.0	-1.2	1.2	-2.1	0.4
Forced vital capacity (FVC), Best measure	0.9	3.1	10.3	-1.0	-0.1	1.2	3.2	1.9	0.8	2.1	-1.7	2.0
Body fat percentage	0.3	1.3	4.2	-0.4	-0.7	-2.1	-0.5	-1.1	0.8	-1.4	-0.2	-1.6
Leg fat percentage (right)	0.3	1.0	3.0	-0.5	-0.5	-1.7	-0.6	-1.4	0.3	-1.1	-1.2	-1.0
Arm fat-free mass (right)	0.5	2.5	5.7	-1.4	0.7	-1.4	-1.7	-2.2	1.1	-2.4	-1.7	-1.1
Exposure to tobacco smoke outside home	0.4	0.5	1.1	-0.1	1.0	0.4	0.8	1.0	0.9	0.7	0.6	0.4
Comparative body size at age 10	1.2	3.4	5.7	1.2	2.4	1.8	0.6	2.2	-1.8	1.7	2.1	2.0
Number of full brothers	2.4	3.0	7.1	1.8	2.2	1.8	1.4	1.6	0.0	2.0	2.7	0.3
Worry too long after embarrassment	0.6	1.0	4.8	-0.4	-0.5	-0.1	-0.2	0.5	1.2	0.5	2.2	-1.2
Seen a psychiatrist for nerves, anxiety, tension or depression	3.1	4.0	12.6	-0.2	-0.5	-0.9	-2.4	-3.5	1.0	-3.4	-2.0	-0.6
Wheeze or whistling in the chest in last year	0.6	1.0	2.2	-1.5	1.0	-0.9	-1.4	-1.1	-0.8	-1.0	-0.9	-0.3
Number of children fathered	0.7	0.8	2.3	-1.1	0.9	0.9	-0.3	-0.5	-1.0	0.2	-0.2	1.5
Reason for reducing amount of alcohol drunk: Health precaution	1.8	2.1	7.1	0.1	-1.1	-2.1	-2.7	-1.0	-0.7	-1.2	-1.2	-1.5
Age at first live birth	0.2	0.3	1.0	1.0	0.6	1.0	-0.4	-0.3	0.1	-0.0	0.2	0.1
Pulse wave peak to peak time	2.5	2.9	6.0	-1.6	-1.0	-0.5	2.4	2.4	1.1	2.4	-0.2	-1.8
Health satisfaction	2.3	3.0	11.2	-1.0	-2.2	-1.2	0.4	-0.2	3.3	0.0	-0.4	-2.9
Shortness of breath walking on level ground	0.9	1.1	2.6	-0.8	1.6	-1.5	-0.9	-0.4	1.5	-0.1	0.8	-0.6
Qualifications: College or University degree	1.3	4.0	12.9	0.9	0.2	-1.7	-3.6	-2.3	-1.2	-3.1	-1.1	-1.0
Eye problems/disorders: None of the above	0.5	0.5	1.5	-1.2	-0.5	0.1	1.1	0.1	1.2	-0.1	-0.4	-0.4
Mouth/teeth dental problems: Loose teeth	0.5	0.6	1.9	-0.8	0.6	-1.4	0.3	0.2	0.6	0.3	-0.7	-1.2
Emphysema/chronic bronchitis	0.7	0.8	2.6	-0.3	1.6	0.2	-1.4	-0.3	-1.1	-0.8	-0.6	0.5
Medication for pain relief, constipation, heartburn	0.1	0.2	0.7	0.6	0.8	0.4	-0.5	0.3	-0.4	-0.2	-0.6	-0.2
Neck or shoulder pain in last month	0.7	0.9	2.2	-1.0	-1.2	-0.9	-0.8	-1.5	0.8	-0.3	-0.7	-0.9
Medication: Blood pressure	0.5	1.0	2.3	-0.1	-1.5	0.8	1.4	1.1	-0.7	0.9	1.0	0.6
Angina (self-reported)	0.8	1.0	3.3	-0.9	-1.8	-1.0	-1.1	-0.9	0.3	-1.2	0.3	0.2
Migraine (self-reported)	0.9	1.1	2.7	0.3	-0.2	-0.4	-1.1	-1.1	1.6	-1.6	0.6	-1.1
Medication: Ibuprofen	0.9	1.0	2.9	-1.5	-1.7	-1.1	-0.8	-1.2	0.1	-0.6	-0.5	-0.4
Medication: Allopurinol	1.0	1.4	2.9	-1.7	-0.2	-1.3	-1.5	-1.4	-0.8	-1.6	0.3	-0.7
Medication: Omeprazole	0.9	1.0	3.4	-0.8	1.6	1.8	1.4	0.0	0.7	-0.2	0.6	0.1
Medication: Seretide 50 evohaler	0.8	0.9	3.7	0.9	-0.2	-0.6	-1.5	0.0	-1.9	-0.1	-0.6	0.8
Mean time to correctly identify matches	0.3	0.5	1.1	-0.2	-1.0	-1.1	-0.9	-0.6	-0.1	-1.0	0.2	-0.7
Heart disease (mother)	0.4	0.5	1.4	-0.7	-0.7	-1.0	-0.0	0.4	0.7	0.0	-0.9	-1.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.9	1.1	2.9	-1.7	-0.9	-0.8	-1.1	-0.9	-1.2	-1.0	-1.0	-0.1
Whole body fat mass	0.3	1.4	3.7	-0.9	-0.3	-1.9	-0.5	-1.2	1.3	-1.5	-0.4	-1.6
Leg fat mass (right)	0.3	1.3	3.5	-0.9	-0.0	-1.9	-0.8	-1.4	0.6	-1.3	-1.0	-1.2
Arm predicted mass (right)	0.5	2.8	5.0	-1.6	0.0	-1.8	-1.7	-2.1	1.2	-2.2	-2.1	-1.1
Pulse rate, automated reading	5.0	16.2	26.4	-1.2	-3.6	-4.3	-4.2	-4.9	2.8	-4.3	-4.3	-5.1
Alcohol intake frequency.	0.4	1.0	3.1	0.2	0.7	-0.6	-1.1	-0.6	0.3	-0.8	1.6	-1.8
Comparative height size at age 10	0.6	3.2	8.4	-0.6	0.5	-2.9	-0.6	-1.2	2.0	-1.4	-1.9	-2.9
Number of full sisters	1.1	1.3	2.3	-1.3	-1.5	-1.5	-0.3	-1.1	1.2	0.3	-1.1	-1.2
Suffer from ‘nerves’	0.4	0.6	2.3	-1.5	0.2	1.0	0.7	0.2	-0.0	0.7	-0.4	1.2
Overall health rating	0.8	1.8	5.2	0.1	-0.2	1.6	1.4	0.6	2.3	1.4	1.8	-0.9
Chest pain or discomfort	0.3	0.4	2.1	-0.6	1.5	-0.0	-0.4	-0.6	-0.4	0.2	0.4	0.1
Had major operations	1.1	1.3	6.4	-0.5	0.7	-0.6	-0.5	0.5	-2.5	0.7	-0.6	1.6
Age at last live birth	1.1	1.7	4.2	0.7	2.0	2.0	1.3	0.7	-0.4	0.9	0.0	1.8
Family relationship satisfaction	0.9	1.1	2.6	-0.3	-0.5	-0.8	0.6	1.5	1.6	1.6	-0.4	-0.8
Leg pain on walking	0.9	1.2	5.0	1.1	1.7	-0.2	-0.4	0.6	0.4	1.0	2.2	0.1
Qualifications: NVQ or HND or HNC or equivalent	0.5	0.6	1.4	-0.2	1.0	0.4	1.1	-0.5	0.9	-0.6	0.1	1.2
Commuting to job workplace: Car/motor vehicle	0.6	0.7	2.0	0.6	-1.2	-0.9	-0.0	0.1	1.4	1.3	0.6	0.4
Illness, injury, bereavement, stress in last 2 years	0.6	0.7	2.4	1.3	1.6	0.4	0.0	-0.1	-0.7	-0.8	1.1	-0.0
Medication: Aspirin	1.4	1.9	4.8	0.5	-2.1	-0.8	1.3	2.2	0.6	2.1	0.6	-0.3
Supplements: Vitamin C	0.7	0.8	3.4	0.8	-1.1	-0.6	-0.1	-0.1	0.3	-0.2	-1.8	-1.1
Knee pain experienced in last month	0.3	0.5	1.9	-1.1	0.4	1.4	0.4	-0.2	0.5	-0.3	-0.2	0.8
Hypertension (Self-reported)	0.5	1.4	4.9	0.2	-0.3	0.9	2.2	1.8	-0.1	1.7	0.9	-0.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.5	0.6	2.5	-0.2	-0.1	0.2	-0.1	-0.8	1.6	-0.8	0.0	-1.3
Illnesses of father: Heart disease	0.8	1.2	2.9	-0.1	-0.8	0.6	1.4	0.9	1.7	1.4	-1.1	-0.6
Illnesses of siblings: Diabetes	1.2	1.5	4.7	-1.1	-0.5	-1.1	-1.2	-1.8	-0.8	-2.2	-1.0	-0.4
Smoking status: Previous	1.2	1.8	5.9	0.7	0.1	-1.1	-0.2	2.1	-1.9	2.4	-0.5	0.2
Forced expiratory volume in 1-second (FEV1), predicted	0.3	0.6	2.5	-0.6	1.1	-0.1	-0.6	-1.6	0.4	-0.8	-0.2	0.3
Whole body fat-free mass	0.3	2.0	4.6	-1.7	1.2	-1.0	-1.2	-1.8	1.1	-2.1	-1.1	-0.9
Leg fat-free mass (right)	0.3	1.6	5.1	-1.6	1.6	-0.4	-0.9	-1.6	0.8	-2.2	-0.2	-0.2
Arm fat percentage (left)	0.2	0.8	2.1	-0.5	0.6	-1.3	-0.5	-0.8	0.3	-1.4	0.8	-0.8
Average weekly red wine intake	0.9	1.4	2.3	0.9	0.4	1.5	1.4	1.4	-0.9	1.5	-0.3	1.4
Handedness (chirality/laterality): Left-handed	0.7	0.8	1.7	-0.2	-0.5	-1.3	-1.1	-0.7	0.8	-0.9	-1.0	-1.0
Mood swings	1.4	2.6	6.2	-0.7	-0.1	-1.6	-2.5	-2.2	0.5	-1.9	-0.2	-2.2
Loneliness, isolation	0.5	0.7	2.1	-0.4	-1.1	-0.6	-1.4	-1.0	0.7	-0.3	-1.0	-0.1
Long-standing illness, disability or infirmity	0.6	1.0	3.0	-1.7	-0.2	-0.4	-0.3	-1.7	0.4	-1.3	-0.9	0.2
Ever had bowel cancer screening	0.4	0.5	1.8	-0.3	-0.0	-0.6	-0.4	-0.6	-1.3	0.2	-0.7	-1.1
Diabetes diagnosed by doctor	0.5	0.8	2.5	-1.6	-0.8	0.3	-0.3	-1.1	-0.4	-0.4	-1.1	1.0
Ever had stillbirth, spontaneous miscarriage or termination	0.4	0.4	2.0	1.4	-0.3	-0.1	-0.4	-0.1	-0.9	-0.1	0.4	0.7
Friendships satisfaction	1.0	1.2	2.9	0.5	-1.4	-0.6	0.6	1.7	1.1	1.7	-1.1	-0.4
Qualifications: nursing, teaching	0.7	1.1	2.2	-0.7	0.9	-1.3	-1.5	-1.4	-0.9	-1.4	-0.5	-0.3
Commuting to job workplace: Walk	0.4	0.5	2.3	0.4	0.5	0.8	0.1	-0.4	-0.5	-0.6	0.1	-1.5
Eye problems/disorders: Cataract	0.9	1.1	4.0	2.0	0.0	0.3	-1.4	0.6	-1.1	1.1	0.6	0.7
Mouth/teeth dental problems: Mouth ulcers	0.5	0.8	2.6	-0.1	0.4	-1.4	-1.6	-0.2	-1.2	-0.5	-0.7	-0.3
Medication for cholesterol	1.6	2.4	7.6	-0.1	-0.8	-1.3	-2.8	-2.1	-0.3	-2.5	-0.5	-0.7
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.8	1.0	1.8	0.7	-0.9	1.3	1.1	1.2	1.0	0.4	1.4	0.2
Back pain experienced in last month	0.9	1.3	3.5	-0.7	-1.6	-1.4	-0.9	-1.3	1.9	-0.4	-0.4	-0.9
Mineral and other dietary supplements	0.2	0.3	0.5	-0.7	0.4	0.6	-0.0	-0.0	0.7	0.3	0.7	0.5
Breast cancer (self-reported)	0.4	0.5	2.0	-0.5	-0.8	-0.7	-0.2	-0.2	0.3	0.2	0.8	-1.4
Asthma (self-reported)	0.3	0.6	1.5	-0.1	0.9	-1.1	-0.9	-1.2	-0.2	-0.4	-0.9	-0.0
Osteoporosis (self-reported)	1.5	1.8	6.7	-0.2	-1.0	-2.6	-2.0	-0.0	-1.9	-0.2	-0.4	-1.1
Osteoarthritis (self-reported)	0.7	0.9	2.8	-0.0	1.7	0.6	0.2	-0.8	-0.7	-1.0	1.6	0.3
Medication: Aspirin	0.7	0.9	2.8	0.7	-1.7	-0.9	0.5	1.6	-0.2	1.0	0.2	0.1
Medication: Gliclazide	0.9	1.1	4.0	-0.5	0.8	0.7	1.9	0.5	2.0	0.1	0.4	0.4
Illnesses of father: None of the above (group 1)	2.5	3.1	8.2	0.4	2.9	0.1	-1.8	-1.4	-2.2	-1.7	0.2	2.6
Smoking status: Current	0.7	1.2	3.2	-0.3	1.0	0.3	-1.7	0.1	-1.8	-0.4	-1.5	1.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.5	1.0	2.0	1.0	-1.3	-0.4	0.7	0.7	0.8	1.4	-1.4	0.2
Whole body water mass	0.4	2.1	5.1	-1.7	1.3	-0.9	-1.3	-1.8	1.1	-2.2	-1.1	-0.8
Leg predicted mass (right)	0.3	1.4	4.4	-1.4	1.7	-0.3	-0.9	-1.5	0.7	-2.1	-0.1	-0.1
Arm fat mass (left)	0.3	1.1	2.7	-0.8	0.5	-1.5	-0.8	-1.3	0.9	-1.6	0.1	-0.9
Number of self-reported non-cancer illnesses	0.5	0.9	3.0	-0.6	-0.4	-0.3	1.3	-1.0	1.0	-0.2	-0.9	-1.7
Average weekly champagne plus white wine intake	0.7	0.9	3.1	0.1	-1.1	0.6	0.2	0.8	-1.3	0.8	-0.6	1.7
Miserableness	0.3	0.5	1.7	-0.9	-0.8	0.3	-1.3	-0.8	0.5	-0.2	-0.2	-0.1
Guilty feelings	0.5	0.8	3.2	-0.4	-0.4	0.1	0.9	0.9	1.0	1.8	-0.7	0.7
Wears glasses or contact lenses	0.3	0.3	0.8	-0.1	0.4	0.1	-0.9	-0.7	-0.7	-0.8	-0.3	-0.3
Ever taken oral contraceptive pill	1.0	1.1	2.5	0.9	0.5	0.4	0.8	1.5	1.3	1.1	1.6	-0.6
Hearing aid user	1.1	1.3	4.3	0.9	-0.2	-1.1	-1.1	-0.9	0.1	-1.2	1.1	-2.1
Mother’s age at death	2.2	2.8	9.4	2.4	1.4	0.5	-1.0	1.4	-3.1	1.3	0.6	1.6
Financial situation satisfaction	1.8	2.2	6.5	0.1	0.7	2.5	1.4	1.4	-0.8	1.3	1.3	2.3
Tinnitus: Yes, now most or all of the time	1.1	1.2	4.0	0.5	-1.4	0.8	0.0	0.6	1.7	0.9	2.0	-0.2
Commuting to job workplace: Public transport	0.9	1.1	2.6	-0.5	1.4	1.6	1.5	0.8	-0.6	-0.3	-1.0	0.8
Eye problems/disorders: Glaucoma	0.3	0.3	1.1	-0.3	-0.9	-0.1	0.5	-0.4	0.5	-0.5	0.1	-1.0
Medication: Blood pressure	0.7	1.3	4.5	-0.1	-0.2	0.2	2.1	1.7	0.1	1.9	0.6	-0.6
Pain type(s) experienced in last month: Hip pain	0.2	0.3	1.2	0.1	1.0	0.5	-0.2	0.2	-0.5	0.2	1.1	-0.0
Supplements: Fish oil (including cod liver oil)	0.2	0.2	1.0	0.7	0.0	0.2	0.4	0.3	-1.0	0.5	-0.4	-0.1
High cholesterol (Self-reported)	1.0	1.8	6.5	0.0	-2.5	-0.5	1.5	1.7	1.1	1.5	-0.8	-0.7
Medication: Bendroflumethiazide	0.4	0.7	2.7	-0.5	-0.1	0.1	0.8	0.0	1.2	0.1	1.0	-1.6
Medication: Paracetamol	0.8	1.2	3.3	-0.4	1.1	0.3	-1.5	-1.8	-1.0	-1.6	-0.4	0.5
Medication: Lisinopril	0.5	0.6	2.0	1.3	-0.2	0.0	-0.3	1.0	-0.7	0.2	1.4	0.1
Medication: Atorvastatin	1.2	1.5	3.3	-0.9	-1.4	-0.2	1.5	1.8	0.7	1.7	-0.4	1.2
Illnesses of father: High blood pressure	0.5	0.6	2.4	1.6	-0.1	-0.5	-0.5	0.5	0.4	0.8	-0.5	-1.1
Alcohol drinker status: Never	1.9	2.3	5.5	-0.9	-0.8	-1.9	-1.1	-1.8	-0.0	-2.3	-1.0	-2.0
Ever smoked	1.7	3.0	9.9	1.4	0.5	-0.6	-1.2	2.4	-3.1	2.2	-1.0	1.3
Basal metabolic rate	0.4	2.0	4.9	-1.6	1.1	-1.0	-1.2	-1.9	1.2	-2.2	-1.1	-0.9
Leg fat percentage (left)	0.3	1.0	2.1	-0.0	-0.8	-1.5	-0.8	-1.4	0.2	-1.4	-1.1	-0.6
Arm fat-free mass (left)	0.6	2.8	5.2	-1.6	0.6	-1.4	-1.6	-2.3	1.3	-2.3	-2.2	-1.0
Number of operations (self-reported)	0.7	1.1	4.2	0.8	0.4	-0.4	-1.3	-0.5	-2.0	-0.9	-1.4	0.1
Average weekly beer plus cider intake	0.2	0.3	0.8	-0.4	0.5	0.3	-0.3	-0.9	0.3	-0.8	-0.5	0.1
Irritability	0.2	0.4	1.3	-1.2	-0.4	-1.0	-0.7	-0.2	-0.6	0.0	-0.2	-0.3
Risk taking	0.5	0.7	2.3	-1.2	-0.4	-0.2	-0.7	-1.5	-0.4	-0.8	-0.9	-0.0
Ever had prostate specific antigen (PSA) test	0.8	0.9	2.9	0.4	-1.0	0.7	-0.1	0.2	-1.7	0.1	-1.0	1.5
Fractured/broken bones in last 5 years	0.7	0.8	3.3	0.6	-0.1	-0.7	-1.8	-1.2	0.1	-1.0	-0.7	-0.6
Age started oral contraceptive pill	0.3	0.4	1.5	0.9	-0.3	-0.4	0.7	1.2	0.3	0.5	0.3	-0.2
Diastolic blood pressure, automated reading	0.8	2.4	5.2	-0.8	-1.7	-0.5	-0.3	-2.1	1.4	-1.6	-2.3	-2.0
Ever depressed for a whole week	0.4	0.5	1.4	0.0	1.0	0.1	0.0	-0.5	1.2	0.6	0.5	-1.1
Unable to work because of sickness or disability	0.2	0.2	0.7	-0.5	-0.3	0.5	-0.1	-0.7	0.8	-0.2	0.1	0.7
Commuting to job workplace: Cycle	0.3	0.4	2.1	-0.5	0.2	1.5	0.5	0.3	-0.6	0.0	0.0	0.9
Myopia	1.0	1.4	4.4	-1.2	-1.4	-1.2	0.4	-1.0	2.1	-0.4	-0.8	-1.2
Vascular/heart problems diagnosed by doctor	0.3	0.9	2.2	-0.8	0.6	-0.3	-1.3	-1.5	0.2	-1.2	-1.3	0.4
Cholesterol lowering medication	1.8	2.6	5.6	0.0	-1.9	0.1	2.3	2.4	1.7	2.3	0.4	-0.6
Medication: Omeprazole (e.g. Zanprol)	0.8	1.0	2.7	-1.1	1.1	0.8	1.0	-0.8	1.6	-0.6	0.5	-1.1
Pain experienced in last month	1.1	1.9	7.5	1.0	1.8	0.3	-1.0	1.1	-2.7	-0.3	0.2	1.6
Supplements: Calcium	0.5	0.6	3.0	-0.1	0.3	-1.7	0.1	-0.1	0.2	0.2	-0.5	-1.4
Basal cell carcinoma (self-reported)	2.0	2.4	7.0	1.0	1.4	-0.3	-2.3	-1.1	-1.9	-2.6	0.9	-0.3
Heart attack/myocardial infarction (self-reported)	0.5	0.6	1.8	-0.0	-1.1	-0.3	0.6	0.3	1.4	0.5	1.4	-0.2
Deep venous thrombosis (DVT) (self-reported)	0.7	1.0	2.4	-1.5	-0.3	-1.5	-1.0	-0.6	0.1	-0.8	-1.3	0.1
Heart disease (siblings)	0.5	0.6	2.7	-0.0	0.5	0.7	-0.2	0.5	-1.4	0.5	0.0	1.6
Alcohol drinker status: Previous	2.1	2.4	8.0	2.8	1.5	1.4	-0.2	1.6	0.6	0.3	2.3	1.0
Pack years of smoking	0.3	0.5	2.4	0.6	0.7	0.2	-0.8	0.2	0.2	-0.4	1.6	-0.5
Impedance of whole body	0.5	2.4	6.2	2.1	-1.6	-0.5	1.6	2.1	0.8	2.5	0.3	-1.1
Leg fat mass (left)	0.3	1.3	2.9	-0.7	-0.2	-1.7	-0.9	-1.5	0.6	-1.5	-1.0	-1.0
Arm predicted mass (left)	0.7	3.5	7.6	-1.7	0.5	-1.6	-1.9	-2.6	1.3	-2.8	-2.1	-1.2