TWAS hub - PLIN4

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Prostate	0.4250	0.128	0.0038	0.180	NA	0.003	NA	0.007	2.7e-05	NA	0.27	NA	0.21
2	TCGA	Head and Neck Squamous Cell Carcinoma	0.0592	0.030	0.0020	0.009	0.01	0.002	NA	0.002	2.8e-02	0.025	0.17	NA	0.16

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Birth weight	7.1	15.4	23.8	4.9	2.6
Ever had stillbirth, spontaneous miscarriage or termination	6.4	6.8	13.7	-3.7	-0.2
Supplements: Calcium	6.1	6.7	12.6	-3.5	0.9
Wheeze or whistling in the chest in last year	4.4	7.9	15.6	-3.9	-0.4
Blood Red Count	3.8	37.0	55.4	-7.4	-4.3
Medication: Laxatives (e.g. Dulcolax, Senokot)	3.8	4.4	7.5	-2.7	-1.1
Cholesterol lowering medication	3.8	5.6	11.0	-0.4	3.3
Illnesses of siblings: Diabetes	3.7	4.6	9.0	-3.0	-0.5
Number of self-reported non-cancer illnesses	3.7	6.4	12.7	-3.6	-0.5
Diverticular disease/diverticulitis (self-reported)	3.3	3.9	6.3	-2.5	-1.2
Unable to work because of sickness or disability	3.2	4.2	5.9	-2.4	-1.6
Supplements: Zinc	3.0	3.2	3.5	-1.7	-1.9
Mineral and other dietary supplements	3.0	4.0	7.5	2.7	-0.8
Alzheimer’s Disease (in mother)	2.8	3.2	4.3	-1.5	2.1
Leg fat-free mass (right)	2.8	15.1	17.1	-4.1	-3.6
Leg predicted mass (right)	2.8	15.0	17.3	-4.2	-3.6
Leg fat-free mass (left)	2.7	14.0	17.3	-4.2	-3.3
Leg predicted mass (left)	2.7	14.1	17.1	-4.1	-3.3
Pain all over the body in last month	2.7	2.8	3.0	-1.6	-1.7
Had major operations	2.7	3.2	5.9	-2.4	-0.7
Respiratory disease	2.6	5.7	10.5	-3.2	1.0
Taking other prescription medications	2.6	4.0	5.0	-2.2	1.7
Impedance of leg (left)	2.5	12.3	22.1	4.7	1.6
Medication: Seretide 50 evohaler	2.5	2.9	4.0	-2.0	-1.3
Whole body fat-free mass	2.5	14.2	14.9	-3.9	-3.7
Whole body water mass	2.5	14.5	16.1	-4.0	-3.6
Impedance of leg (right)	2.4	11.8	20.1	4.5	1.9
Trunk fat-free mass	2.4	14.0	14.2	-3.7	-3.8
Trunk predicted mass	2.4	13.7	14.0	-3.7	-3.7
Birth weight of first child	2.4	4.3	4.7	2.2	2.0
Arm predicted mass (left)	2.4	12.2	12.4	-3.5	-3.5
Primary Biliary Cirrhosis	2.3	3.2	5.3	-1.1	2.3
Asthma	2.3	4.4	8.8	-3.0	-0.3
Exposure to tobacco smoke at home	2.3	2.5	4.8	-0.5	-2.2
Arm fat-free mass (right)	2.3	11.6	11.9	-3.4	-3.5
Mouth/teeth dental problems: Loose teeth	2.3	2.7	2.9	-1.7	-1.6
Comparative height size at age 10	2.3	12.5	19.3	-2.4	-4.4
Medication: Lisinopril	2.3	3.0	6.0	-2.4	-0.1
Basal metabolic rate	2.3	12.8	14.3	-3.8	-3.4
Arm fat-free mass (left)	2.3	11.9	12.9	-3.6	-3.3
Myopia	2.3	3.4	3.8	-1.7	-1.9
Number of treatments/medications taken	2.2	4.0	5.8	-2.4	1.5
Medication: Simvastatin	2.2	3.2	6.4	-0.2	2.5
Serious illness, injury or assault of a close relative in last 2 years	2.2	2.6	4.2	-2.1	-1.0
Health satisfaction	2.2	2.8	5.6	-2.4	0.1
Tinnitus: Yes, now most or all of the time	2.2	2.5	3.5	-1.2	1.9
Ever smoked	2.2	3.9	7.8	-2.8	0.1
Relative age voice broke	2.1	3.1	5.9	0.6	2.4
Medication: Atenolol	2.1	2.7	4.5	-0.9	2.1
Past tobacco smoking	2.1	3.8	7.7	2.8	-0.0
High blood pressure (siblings)	2.1	3.1	4.7	-2.2	1.2
Arm predicted mass (right)	2.0	10.3	10.9	-3.3	-3.1
Alcohol drinker status: Previous	2.0	2.2	4.2	-2.0	-0.6
Ulcerative Colitis (UC)	1.9	3.5	5.9	2.4	1.1
Hair/balding pattern: Pattern 2	1.9	2.4	4.2	0.8	-2.1
Illnesses of siblings	1.9	2.7	5.1	2.3	-0.6
Overall health rating	1.9	4.1	8.2	-2.9	0.3
Long-standing illness, disability or infirmity	1.9	2.9	5.6	-2.4	0.4
Asthma (self-reported)	1.9	3.8	7.7	-2.8	-0.1
Osteoarthritis (self-reported)	1.9	2.4	3.7	-1.0	1.9
Medication: Gliclazide	1.9	2.1	3.3	-1.8	-1.0
Pain type(s) experienced in last month: Hip pain	1.9	2.4	3.7	-1.9	1.0
Impedance of whole body	1.9	9.8	16.6	4.1	1.8
Type 2 Diabetes (T2D) (2018)	1.8	3.3	6.4	-2.5	-0.4
Hearing difficulty/problems: Yes	1.8	2.7	5.4	-0.0	2.3
Falls in the last year	1.8	2.5	2.9	-1.7	-1.4
Blood clot in the leg (DVT)	1.8	2.3	4.1	-2.0	-0.7
Medication for cholesterol, blood pressure or diabetes	1.8	3.0	5.2	2.3	-0.9
Age at last live birth	1.8	2.7	4.6	-2.1	-0.8
Medication: Aspirin	1.8	2.4	3.7	-1.9	1.0
Medication: Aspirin	1.8	2.3	3.1	-1.8	1.2
Hearing aid user	1.8	2.1	3.5	1.9	0.8
Supplements: Fish oil (including cod liver oil)	1.8	2.3	4.6	-2.1	0.2
Average weekly beer plus cider intake	1.8	2.6	4.6	0.7	-2.1
Irritable Bowel Disease (IBD)	1.7	4.1	7.0	2.7	1.1
Qualifications: CSEs or equivalent	1.7	2.2	4.5	0.2	-2.1
Financial difficulties in last 2 years	1.7	2.3	2.3	-1.5	-1.5
Allergy	1.7	3.9	7.8	2.8	0.3
Medication: Ramipril	1.7	2.2	4.0	-0.6	2.0
Shortness of breath walking on level ground	1.7	2.0	4.0	-2.0	-0.1
Migraine (self-reported)	1.7	2.1	3.0	-1.1	-1.7
Suffer from ‘nerves’	1.7	2.6	5.1	-2.3	-0.3
Smoking status: Previous	1.7	2.6	5.2	-2.3	0.2
Ever used hormone-replacement therapy (HRT)	1.6	2.0	3.0	-1.7	1.0
Noisy workplace	1.6	2.0	3.9	0.1	2.0
Pulse wave Arterial Stiffness index	1.6	1.8	3.0	-0.8	-1.7
Alcohol drinker status: Never	1.6	1.9	3.8	1.9	-0.0
Deep venous thrombosis (DVT) (self-reported)	1.6	2.0	3.3	-1.8	-0.8
Blood Platelet Count	1.5	17.6	31.1	-5.6	-2.0
Father’s age at death	1.5	2.0	3.2	-1.8	-0.9
Worrier / anxious feelings	1.5	2.9	4.0	-2.0	-1.3
Lung cancer (father)	1.5	1.7	2.8	-0.8	-1.7
Neck or shoulder pain in last month	1.5	2.1	2.1	-1.5	-1.4
Number of operations (self-reported)	1.5	2.2	2.7	-1.3	1.6
Fasting Glucose	1.4	1.7	3.3	0.4	-1.8
Height	1.4	27.8	31.5	-4.9	-5.6
Depression (self-reported)	1.4	1.7	2.1	-1.5	-1.1
Seen doctor (GP) for nerves, anxiety, tension or depression	1.4	2.2	3.2	-1.0	-1.8
Medication for pain relief, constipation, heartburn	1.4	2.3	4.0	2.0	-0.8
Medication: Omeprazole	1.4	1.7	2.8	-1.7	0.8
Knee pain experienced in last month	1.4	2.1	4.2	-2.0	-0.3
Medication for cholesterol	1.4	2.1	2.4	1.5	-1.4
Age started oral contraceptive pill	1.4	1.7	3.4	-0.3	1.8
Verbal and Numeric Reasoning (VNR)	1.3	3.2	5.1	1.1	2.3
Eye problems/disorders: Diabetes related eye disease	1.3	1.4	2.6	-1.6	-0.4
Diabetes (mother)	1.3	1.7	2.1	-1.5	-1.1
Alcohol intake versus 10 years previously	1.3	1.9	2.2	1.2	1.5
Headache pain in last month	1.3	2.3	3.1	1.8	-1.2
Seen a psychiatrist for nerves, anxiety, tension or depression	1.3	1.7	2.5	-1.0	1.6
Leg pain on walking	1.3	1.6	3.2	-1.8	0.1
Illnesses of father: Heart disease	1.3	1.8	3.4	0.4	1.9
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.3	2.7	3.2	1.5	1.8
Wears glasses or contact lenses	1.3	1.5	2.0	-1.0	1.4
Commuting to job workplace: Public transport	1.3	1.5	1.6	1.2	1.3
High cholesterol (Self-reported)	1.3	2.3	4.2	-0.6	2.1
Intelligence (Savage-Jansen 2018)	1.2	3.7	5.8	1.3	2.4
LDL Cholesterol	1.2	1.8	3.6	-1.9	0.0
Rheumatoid Arthritis	1.2	1.6	3.2	-1.8	0.0
Waist Hip Ratio (WHR)	1.2	5.4	8.9	3.0	1.4
Smoking Status	1.2	2.9	5.4	-2.3	0.6
Cardiovascular Disease	1.2	3.9	7.6	-2.8	0.5
Diabetes (self-reported)	1.2	1.9	3.8	-1.9	0.0
Impedance of arm (left)	1.2	5.5	7.8	2.8	1.8
Exposure to tobacco smoke outside home	1.2	1.7	3.1	1.8	0.5
Pulse wave peak to peak time	1.2	1.4	2.2	0.7	1.5
Medication: Blood pressure	1.2	2.2	4.0	-2.0	0.6
Ever had bowel cancer screening	1.2	1.5	2.6	-1.6	0.6
Qualifications: nursing, teaching	1.2	1.9	3.5	-0.6	1.9
Bilateral oophorectomy (both ovaries removed)	1.1	1.3	1.8	-1.4	-0.9
Neuroticism score	1.1	2.4	4.8	-2.2	-0.2
Weight	1.1	5.4	8.8	-3.0	-1.4
Hip circumference	1.1	4.9	9.9	-3.1	-0.1
Medication: Cholesterol lowering	1.1	1.8	3.1	-0.7	1.8
Number of children fathered	1.1	1.2	2.4	-1.5	-0.3
Hypertension (Self-reported)	1.1	3.1	5.2	-2.3	1.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.1	1.2	2.3	0.4	1.5
Eye problems/disorders: Cataract	1.1	1.3	1.6	-1.0	1.3
Osteoporosis (self-reported)	1.1	1.4	1.6	-1.1	-1.3
Mother’s age at death	1.1	1.4	2.7	-0.2	-1.6
Vascular/heart problems diagnosed by doctor	1.1	3.1	5.0	2.2	-1.1
Schizophrenia (2018)	1.0	2.0	4.0	-2.0	0.0
HbA1C	1.0	1.1	1.7	-0.7	-1.3
Lupus	1.0	1.4	2.7	1.6	0.5
Frequency of depressed mood in last 2 weeks	1.0	1.4	2.7	-1.6	-0.2
Ever had hysterectomy (womb removed)	1.0	1.1	1.6	-1.3	0.8
Systolic blood pressure, automated reading	1.0	3.0	5.3	0.8	2.3
High blood pressure	1.0	2.8	5.2	-2.3	0.6
Alcohol usually taken with meals	1.0	1.7	2.8	-0.7	1.7
Had menopause	1.0	1.3	2.3	-0.5	1.5
Standing height	1.0	9.8	15.0	-2.2	-3.9
Number of full brothers	1.0	1.3	1.7	-1.3	-0.9
Family relationship satisfaction	1.0	1.2	2.0	-0.7	-1.4
Diabetes diagnosed by doctor	1.0	1.6	3.1	-1.8	0.2
Illnesses of father: None of the above (group 1)	1.0	1.3	2.4	-0.4	-1.6
Medication: Blood pressure	1.0	1.9	2.5	-1.2	1.6
Basal cell carcinoma (self-reported)	1.0	1.2	1.3	1.1	-1.1
Bipolar Disorder or Schizophrenia	0.9	2.2	4.5	-2.1	0.0
Crohns Disease (2017)	0.9	2.1	3.5	1.9	0.8
Age at First Birth	0.9	1.3	2.6	-1.6	-0.0
Average weekly spirits intake	0.9	1.1	2.2	1.5	-0.2
Severe depression (siblings)	0.9	1.0	1.2	-1.1	0.8
Fed-up feelings	0.9	1.6	2.8	-1.7	-0.6
Stomach or abdominal pain in last month	0.9	1.1	1.1	-1.1	-1.0
Supplements: Glucosamine	0.9	1.1	1.4	-1.2	0.9
Nervous feelings	0.9	1.8	3.2	-1.8	0.5
Qualifications: A levels/AS levels or equivalent	0.9	1.9	1.9	-1.4	1.4
Pulse wave reflection index	0.9	1.1	2.0	-0.3	-1.4
Emphysema/chronic bronchitis	0.9	1.0	1.8	-0.3	-1.4
Commuting to job workplace: Car/motor vehicle	0.9	1.0	1.5	-0.7	-1.2
Illness, injury, bereavement, stress in last 2 years	0.9	1.1	1.2	1.0	1.1
Financial situation satisfaction	0.9	1.1	2.1	-1.5	-0.2
Ever had prostate specific antigen (PSA) test	0.9	1.0	2.0	-1.4	-0.4
Alzheimer’s Disease (including proxy)	0.8	1.2	2.3	-0.1	1.5
Allergy or Eczema	0.8	2.0	3.8	-2.0	0.3
Other serious medical condition/disability diagnosed by doctor	0.8	1.0	1.3	-0.9	1.1
Serious illness, injury or assault to yourself	0.8	0.9	1.8	-0.1	1.3
Sitting height	0.8	5.4	10.4	-0.7	-3.2
Impedance of arm (right)	0.8	3.9	4.5	2.1	1.8
Hair/balding pattern: Pattern 3	0.8	1.2	2.0	-0.6	1.4
Loud music exposure frequency	0.8	0.8	1.6	-1.3	0.2
Medication: Paracetamol	0.8	1.4	2.7	-1.6	-0.3
Medication: Amlodipine	0.8	1.2	2.3	-1.5	-0.1
Eye problems/disorders: Glaucoma	0.8	1.0	1.9	1.4	0.1
Fractured/broken bones in last 5 years	0.8	1.0	1.3	-1.1	-0.8
Relative age of first facial hair	0.7	1.4	2.9	-0.1	1.7
Townsend deprivation index at recruitment	0.7	1.0	2.0	-0.0	-1.4
Had other major operations	0.7	0.9	1.6	-0.5	1.3
Qualifications: None of the above	0.7	1.6	2.3	1.5	-0.9
Arm fat mass (right)	0.7	2.7	5.4	-2.3	-0.1
Angina (self-reported)	0.7	0.9	1.5	-0.5	1.2
Mood swings	0.7	1.2	2.1	-0.6	-1.4
Worry (Nagel 2018)	0.6	1.3	2.6	-1.6	-0.1
Breast Cancer	0.6	1.4	2.6	1.6	-0.5
Chronotype (morning person)	0.6	1.3	2.5	1.6	0.2
Angina	0.6	0.8	1.0	-0.8	1.0
Frequency of tenseness / restlessness in last 2 weeks	0.6	1.0	2.0	-1.4	-0.1
Heart attack	0.6	0.8	0.8	-0.9	0.9
Illnesses of mother	0.6	0.7	1.4	-0.1	-1.2
Qualifications: O levels/GCSEs or equivalent	0.6	0.9	1.8	-1.4	0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.6	0.7	0.8	0.9	-0.7
Pulse rate, automated reading	0.6	1.9	3.7	-1.9	-0.1
Chest pain or discomfort	0.6	0.8	1.6	-1.3	-0.2
Forced expiratory volume in 1-second (FEV1), predicted	0.6	1.2	2.1	-0.6	-1.4
Average weekly red wine intake	0.6	0.8	1.5	-0.4	1.2
Arm fat mass (left)	0.6	2.6	5.2	-2.3	-0.1
Risk taking	0.6	0.9	1.7	-1.3	0.3
Medication: Omeprazole (e.g. Zanprol)	0.6	0.8	1.2	-1.1	0.6
Heart attack/myocardial infarction (self-reported)	0.6	0.7	1.0	-0.6	1.0
Lung FVC	0.5	2.3	3.0	1.3	1.7
Hayfever, allergic rhinitis or eczema	0.5	1.0	2.0	-1.4	0.1
Chronic bronchitis/emphysema (father)	0.5	0.5	0.7	-0.6	-0.8
Body mass index (BMI)	0.5	1.9	3.7	-1.9	0.4
Waist circumference	0.5	1.9	3.7	-1.9	0.4
Ever unenthusiastic/disinterested for a whole week	0.5	0.6	1.1	-0.0	-1.1
Arm fat percentage (right)	0.5	1.8	2.5	-1.6	1.1
Breastfed as a baby	0.5	0.6	1.0	-0.5	1.0
Qualifications: NVQ or HND or HNC or equivalent	0.5	0.6	0.6	0.8	-0.8
Guilty feelings	0.5	0.7	1.4	-0.2	1.2
Ever taken oral contraceptive pill	0.5	0.5	0.6	-0.7	-0.7
Commuting to job workplace: Cycle	0.5	0.6	1.2	0.1	-1.1
Depressed Affect (Nagel 2018)	0.4	0.8	1.3	-0.5	-1.1
Neuroticism (2016)	0.4	0.6	1.2	-1.1	-0.1
Schizophrenia (2014)	0.4	1.0	2.0	-1.4	0.0
Lung FEV1/FVC ratio	0.4	2.1	4.0	2.0	-0.3
Neuroticism	0.4	1.1	2.2	-1.5	0.1
Hand grip strength (left)	0.4	0.9	1.8	1.4	-0.2
Sensitivity / hurt feelings	0.4	0.8	1.4	-1.2	-0.3
Medication for hormone replacement therapy	0.4	0.5	0.6	-0.8	-0.6
Hand grip strength (right)	0.4	1.1	2.2	1.5	0.0
Maternal smoking around birth	0.4	0.6	0.7	-0.8	-0.8
Trunk fat mass	0.4	1.7	3.4	-1.8	0.0
Number of incorrect matches in round	0.4	0.7	1.1	-1.1	-0.6
Hearing difficulty/problems with background noise	0.4	0.6	1.2	-1.1	0.0
Fluid intelligence score	0.4	0.8	1.3	0.5	1.1
Ever highly irritable/argumentative for 2 days	0.4	0.4	0.9	0.1	-0.9
Mouth/teeth dental problems: Bleeding gums	0.4	0.5	0.6	-0.8	0.6
Comparative body size at age 10	0.4	1.1	1.6	1.3	-0.8
Reason for reducing amount of alcohol drunk: Health precaution	0.4	0.4	0.7	0.4	0.8
Qualifications: College or University degree	0.4	1.1	1.4	-1.2	0.9
Eye problems/disorders: None of the above	0.4	0.4	0.6	0.7	-0.5
Medication: Ibuprofen	0.4	0.5	1.0	-1.0	0.1
Heart disease (mother)	0.4	0.4	0.6	-0.8	0.5
Whole body fat mass	0.4	1.8	3.6	-1.9	-0.2
Leg fat mass (right)	0.4	1.7	3.5	-1.9	-0.1
Loneliness, isolation	0.4	0.6	1.2	-1.1	-0.1
Medication: Bendroflumethiazide	0.4	0.7	0.7	-0.9	-0.8
Ever depressed for a whole week	0.4	0.5	0.9	-1.0	-0.0
Heart disease (siblings)	0.4	0.5	0.5	-0.7	0.7
Leg fat mass (left)	0.4	1.7	3.5	-1.9	-0.2
Bipolar Disorder (2018)	0.3	0.5	0.9	-1.0	0.0
Vitamin and mineral supplements	0.3	0.4	0.8	0.1	-0.9
Medication: Metformin	0.3	0.5	0.8	-0.9	0.4
Diabetes (father)	0.3	0.4	0.5	-0.7	0.5
Current tobacco smoking	0.3	0.4	0.8	-0.9	0.2
Multivitamins +/- minerals	0.3	0.4	0.5	0.7	0.6
Medication: Levothyroxine sodium	0.3	0.6	1.0	1.0	0.4
Time employed in main current job	0.3	0.4	0.7	-0.8	-0.3
Tense / ‘highly strung’	0.3	0.5	0.8	-0.9	0.3
Body fat percentage	0.3	1.0	1.4	-0.8	1.2
Leg fat percentage (right)	0.3	0.9	1.7	-0.5	1.3
Worry too long after embarrassment	0.3	0.5	1.0	-1.0	-0.1
Age at first live birth	0.3	0.6	0.7	-0.8	-0.6
Medication: Allopurinol	0.3	0.4	0.7	-0.1	-0.8
Arm fat percentage (left)	0.3	1.4	1.8	-1.3	1.0
Smoking status: Current	0.3	0.5	0.9	-1.0	0.0
Medication: Paracetamol	0.3	0.5	1.1	-1.0	0.0
Medication: Atorvastatin	0.3	0.4	0.8	-0.2	0.9
Irritability	0.3	0.5	1.0	0.1	-1.0
Pain experienced in last month	0.3	0.4	0.8	0.9	0.1
Neuroticism (Nagel 2018)	0.2	0.4	0.6	-0.6	-0.7
Prostate Cancer	0.2	0.3	0.3	0.4	0.6
Mean Putamen Volume	0.2	0.3	0.5	0.2	-0.7
Heel T-Score	0.2	1.4	2.3	-0.7	1.5
BMI	0.2	1.4	2.6	-1.6	0.3
Hair Pigment	0.2	6.8	12.7	3.6	1.0
Trunk fat percentage	0.2	0.9	1.2	-0.8	1.1
Hayfever/allergic rhinitis (self-reported)	0.2	0.3	0.5	-0.4	0.7
Forced expiratory volume in 1-second (FEV1)	0.2	0.7	1.3	1.1	-0.3
Prospective memory result	0.2	0.2	0.3	-0.6	0.3
Forced expiratory volume in 1-second (FEV1), Best measure	0.2	0.6	1.0	0.4	-1.0
Medication: Ventolin 100micrograms inhaler	0.2	0.2	0.2	-0.5	-0.4
Supplements: Vitamin C	0.2	0.2	0.2	0.4	0.5
Handedness (chirality/laterality): Left-handed	0.2	0.2	0.3	0.5	0.4
Average weekly champagne plus white wine intake	0.2	0.3	0.5	0.7	0.4
Leg fat percentage (left)	0.2	0.6	1.1	-0.4	1.0
Alzheimer’s Disease (in father)	0.1	0.2	0.2	0.4	0.4
Ovarian Cancer	0.1	0.1	0.1	-0.2	0.4
Body Mass Index (BMI) (2010)	0.1	0.1	0.2	-0.5	0.0
Triglycerides	0.1	0.1	0.2	0.5	0.0
Ulcerative Colitis	0.1	0.1	0.3	0.5	0.0
Systolic Blood Pressure	0.1	0.7	1.4	-0.2	1.2
Tanning	0.1	1.2	1.5	0.9	-1.2
Medication: Co-codamol	0.1	0.1	0.2	0.4	0.2
Average weekly fortified wine intake	0.1	0.1	0.1	-0.3	-0.1
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.3	0.7	-0.8	-0.1
Tinnitus: Yes, but not now, but have in the past	0.1	0.2	0.3	-0.6	-0.0
High blood pressure (mother)	0.1	0.2	0.3	0.6	0.3
Heel bone mineral density (BMD) T-score, automated (right)	0.1	0.3	0.4	-0.5	-0.7
Mouth/teeth dental problems	0.1	0.1	0.1	0.4	0.1
Frequency of tiredness / lethargy in last 2 weeks	0.1	0.2	0.5	-0.7	-0.0
Number of live births	0.1	0.1	0.2	0.1	0.5
Happiness	0.1	0.1	0.2	0.1	-0.4
Mouth/teeth dental problems: Dentures	0.1	0.1	0.2	-0.0	-0.5
Medication: Ibuprofen (e.g. Nurofen)	0.1	0.1	0.1	-0.3	0.3
Medication: Lansoprazole	0.1	0.1	0.2	-0.2	0.4
Length of working week for main job	0.1	0.1	0.2	-0.4	0.1
Peak expiratory flow (PEF)	0.1	0.3	0.4	0.7	-0.5
Glaucoma (self-reported)	0.1	0.1	0.3	-0.1	-0.5
Gout (self-reported)	0.1	0.1	0.2	-0.2	-0.5
Hypothyroidism/myxoedema (self-reported)	0.1	0.2	0.2	0.4	0.4
Chronic bronchitis/emphysema (mother)	0.1	0.1	0.2	-0.2	-0.4
Forced vital capacity (FVC), Best measure	0.1	0.5	1.1	-0.1	-1.0
Mean time to correctly identify matches	0.1	0.2	0.4	0.2	0.6
Alcohol intake frequency.	0.1	0.1	0.2	-0.5	0.1
Friendships satisfaction	0.1	0.1	0.2	-0.5	0.1
Commuting to job workplace: Walk	0.1	0.1	0.1	-0.1	0.4
Mouth/teeth dental problems: Mouth ulcers	0.1	0.1	0.2	0.4	-0.1
Back pain experienced in last month	0.1	0.2	0.3	0.5	0.4
Breast cancer (self-reported)	0.1	0.1	0.1	-0.3	-0.3
Depression (Nagel 2018)	0.0	0.1	0.1	-0.4	0.0
Schizophrenia vs Biploar Disorder	0.0	0.0	0.0	0.0	0.0
Major Depression (MDD)	0.0	0.0	0.0	0.0	0.0
Reaction Time	0.0	0.1	0.1	0.3	-0.2
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0
Coronary Artery Disease (CAD)	0.0	0.0	0.0	0.0	0.0
Crohns Disease (2012)	0.0	0.0	0.1	0.3	0.0
HDL Cholesterol	0.0	0.0	0.0	-0.0	0.0
Type 2 Diabetes (T2D) (2012)	0.0	0.0	0.0	0.0	0.0
Blood Eosinophil Count	0.0	0.3	0.5	-0.5	-0.7
Blood White Count	0.0	0.1	0.1	0.3	-0.3
Hypothyroidism (self reported)	0.0	0.0	0.0	-0.1	-0.0
Pack years adult smoking proportion	0.0	0.0	0.0	-0.1	-0.1
Frequency of unenthusiasm / disinterest in last 2 weeks	0.0	0.1	0.1	-0.1	0.3
Age when periods started (menarche)	0.0	0.1	0.1	0.2	-0.3
Forced vital capacity (FVC)	0.0	0.1	0.2	0.3	-0.4
Pulse rate	0.0	0.0	0.0	-0.1	-0.2
Hair/balding pattern: Pattern 4	0.0	0.1	0.2	-0.4	-0.3
Number of full sisters	0.0	0.0	0.0	-0.0	-0.0
Miserableness	0.0	0.1	0.1	0.4	-0.1
Illnesses of father: High blood pressure	0.0	0.1	0.1	-0.1	-0.3
Diastolic blood pressure, automated reading	0.0	0.0	0.0	-0.2	-0.0
Pack years of smoking	0.0	0.0	0.0	-0.1	0.2

Hub : Genes

PLIN4

Models

Trait associations