Hub : Genes

POLL

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0860	0.0270	1.0e-08	0.104	0.076	0.110	0.100	0.106	1.4e-12	1.7e-09	2.6e-13	3.7e-12	8.2e-13
2	GTEx	Cells Transformed fibroblasts	0.0430	0.0230	8.4e-03	0.001	NA	-0.003	NA	-0.003	2.7e-01	NA	7.1e-01	NA	6.7e-01
3	GTEx	Small Intestine Terminal Ileum	0.3230	0.1100	8.1e-03	0.075	NA	0.100	NA	0.111	9.7e-03	NA	3.1e-03	NA	1.9e-03
4	GTEx	Testis	0.1050	0.0460	3.0e-03	0.124	NA	0.082	NA	0.079	3.8e-06	NA	1.8e-04	NA	2.1e-04
5	ROSMAP	Brain Pre-frontal Cortex	0.0783	0.0257	6.1e-08	0.050	0.059	0.046	0.058	0.048	4.8e-07	4.4e-08	1.3e-06	6.3e-08	7.7e-07
6	TCGA	Brain Lower Grade Glioma	0.0167	0.0108	5.4e-03	0.018	0.013	0.014	NA	0.013	3.0e-03	1.1e-02	8.5e-03	NA	1.1e-02
7	TCGA	Lung Squamous Cell Carcinoma	0.0413	0.0227	3.4e-06	0.037	0.052	0.045	NA	0.042	4.4e-05	1.2e-06	6.9e-06	NA	1.4e-05
8	TCGA	Pancreatic Adenocarcinoma	0.0590	0.0390	3.2e-03	0.016	0.043	0.004	NA	0.006	6.8e-02	6.5e-03	2.0e-01	NA	1.8e-01
9	TCGA	Thyroid Carcinoma	0.0230	0.0150	2.1e-03	0.016	0.027	0.025	NA	0.025	9.2e-03	1.1e-03	1.5e-03	NA	1.6e-03

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Bipolar Disorder (2018)	0.6	0.9	2.3	1.5	1.1	0.7	-1.2	0.7	0.4	0.8	1.0	0.5
Bipolar Disorder or Schizophrenia	0.4	1.1	5.6	2.4	1.1	-0.1	-1.4	-0.2	0.1	0.2	0.9	-0.2
Depressed Affect (Nagel 2018)	0.3	0.5	1.8	-0.5	-0.5	0.4	0.9	-0.9	-1.3	-0.4	0.4	-0.7
Depression (Nagel 2018)	0.4	0.6	1.7	-0.8	-0.5	-1.0	1.3	-0.8	-1.0	-0.4	-0.0	-0.5
Intelligence (Savage-Jansen 2018)	4.0	12.3	24.3	-3.5	-3.0	-0.9	3.4	-4.9	-3.8	-3.5	-3.5	-3.7
Neuroticism (Nagel 2018)	0.6	1.4	5.4	0.6	1.6	0.2	-0.0	-0.1	-0.5	1.5	2.3	1.1
Schizophrenia (2018)	0.3	0.7	3.3	1.8	0.6	-0.7	-0.8	-0.8	-0.2	-0.3	0.3	-0.6
Schizophrenia vs Biploar Disorder	0.4	0.5	1.2	1.1	0.8	-0.8	-0.8	0.3	0.8	0.2	0.5	0.2
Worry (Nagel 2018)	2.0	4.1	11.0	1.4	2.9	-0.1	-0.8	1.1	0.6	2.7	3.3	2.5
Alzheimer’s Disease (in mother)	0.1	0.1	0.6	0.0	0.1	-0.8	0.0	0.3	-0.3	-0.0	0.2	-0.1
Alzheimer’s Disease (in father)	1.5	1.6	3.3	1.3	1.3	-1.8	-0.7	1.4	0.7	1.3	1.2	1.3
Alzheimer’s Disease (including proxy)	0.4	0.5	1.7	1.0	0.5	-1.3	-0.6	0.7	0.4	0.5	0.6	0.4
Crohns Disease (2017)	0.3	0.6	1.7	-1.0	-0.1	-1.2	1.3	-0.3	-0.6	-0.5	-0.4	-0.4
Irritable Bowel Disease (IBD)	0.1	0.3	1.3	-1.0	0.3	-0.6	1.1	-0.1	-0.4	-0.1	-0.1	-0.1
Ulcerative Colitis (UC)	0.1	0.2	0.4	-0.6	0.5	0.1	0.7	0.1	-0.2	0.3	0.3	0.3
Major Depression (MDD)	1.7	2.1	3.1	1.7	1.8	-1.6	-1.1	0.5	1.2	1.7	1.5	1.5
Reaction Time	1.5	2.9	5.5	-1.5	-1.4	-1.7	2.2	-2.1	-2.3	-1.0	-1.2	-1.3
Verbal and Numeric Reasoning (VNR)	4.0	9.5	18.4	-2.9	-3.2	0.3	2.4	-4.3	-2.8	-3.4	-3.4	-3.4
Breast Cancer	2.5	6.0	10.8	3.1	1.9	0.2	-3.3	1.7	3.1	2.5	1.9	2.7
Ovarian Cancer	0.5	0.6	1.7	0.7	0.0	0.8	-1.0	1.2	1.3	0.2	-0.1	0.4
Prostate Cancer	0.2	0.3	1.0	0.3	0.8	0.3	-0.5	-0.2	-0.1	0.5	1.0	0.5
Age at First Birth	0.7	1.0	2.0	-0.6	-0.8	-0.9	0.6	-1.4	-0.8	-1.3	-1.1	-1.3
Bipolar Disorder (2011)	4.1	3.9	8.3	2.9	1.9	-0.0	-2.5	1.2	1.9	2.0	2.0	2.0
Body Mass Index (BMI) (2010)	0.7	1.0	3.3	0.3	-1.3	-1.0	-0.3	-0.2	0.1	-1.4	-1.8	-1.0
Coronary Artery Disease (CAD)	1.2	1.5	2.8	-0.7	-1.6	-0.5	0.9	-0.6	-0.9	-1.6	-1.6	-1.7
Crohns Disease (2012)	0.2	0.3	1.1	0.3	1.0	-1.0	-0.1	0.3	0.3	0.3	0.7	0.2
Mean Putamen Volume	2.0	2.3	3.5	-1.6	-1.7	1.1	1.0	-1.7	-1.0	-1.7	-1.9	-1.7
Fasting Glucose	0.9	1.0	3.1	1.0	-0.1	1.8	-1.4	0.8	1.3	0.3	-0.0	0.7
HbA1C	0.5	0.6	2.7	0.8	0.0	-0.2	-0.6	1.6	0.9	0.5	-0.0	0.7
HDL Cholesterol	0.3	0.5	1.3	-1.1	-0.8	0.8	0.8	-0.1	-0.6	-0.6	-0.6	-0.5
LDL Cholesterol	0.6	0.9	2.0	0.9	-0.9	1.4	-1.2	-0.7	0.5	-0.8	-0.9	-0.8
Lupus	1.3	2.0	3.6	-1.6	-1.5	0.5	1.1	-1.9	-1.5	-1.4	-1.3	-1.3
Neuroticism (2016)	0.5	0.7	3.2	0.1	-0.4	1.1	0.1	-1.8	-0.9	-0.6	-0.3	-0.8
Primary Biliary Cirrhosis	2.4	3.5	12.2	-1.7	-2.4	3.5	0.8	-0.6	-0.9	-1.7	-2.0	-1.4
Rheumatoid Arthritis	0.8	1.2	2.8	-1.7	-0.8	1.1	1.4	-0.2	-1.4	-0.9	-0.7	-0.9
Schizophrenia (2014)	0.3	0.6	2.7	1.6	0.3	0.0	-0.7	-0.9	-0.2	-0.5	0.1	-0.9
Triglycerides	0.7	1.1	2.2	1.0	0.3	-0.2	-0.8	1.3	1.5	1.2	0.5	1.5
Type 2 Diabetes (T2D) (2012)	0.4	0.5	2.1	0.9	0.2	1.4	-0.9	0.2	0.6	-0.1	-0.3	-0.1
Ulcerative Colitis	0.3	0.5	1.7	-0.1	1.1	-1.3	0.3	-0.6	-0.1	0.4	0.7	0.3
Blood Eosinophil Count	0.0	0.3	1.0	-0.0	-0.2	1.0	-0.2	-0.1	-0.1	-0.9	-0.1	-0.8
Blood Platelet Count	0.4	5.1	21.6	-1.3	-2.5	4.7	0.5	-2.2	-0.8	-1.9	-1.8	-1.9
Blood Red Count	0.3	3.2	8.6	-2.2	-0.5	-1.2	2.9	-1.0	-2.9	-1.4	-0.3	-1.7
Blood White Count	0.5	3.4	7.6	1.5	2.4	1.4	-1.6	1.9	1.2	1.9	2.8	1.7
Heel T-Score	0.4	3.4	13.0	-1.5	-1.3	3.6	0.6	-1.2	-0.8	-2.2	-1.4	-2.1
BMI	1.7	9.8	18.7	-2.5	-4.2	0.4	1.9	-2.0	-1.9	-4.3	-4.3	-4.0
Height	1.8	35.2	57.3	5.6	5.8	1.6	-6.5	6.0	7.6	6.3	5.7	6.5
Waist Hip Ratio (WHR)	0.5	2.3	4.9	1.2	1.9	0.1	-0.9	2.2	1.1	1.6	2.0	1.6
Systolic Blood Pressure	5.2	25.9	38.8	5.8	6.2	-1.1	-4.7	4.1	4.7	5.8	5.8	5.6
Smoking Status	2.2	5.1	13.2	0.9	3.6	-1.8	-0.3	2.0	1.2	2.6	3.6	2.0
Allergy or Eczema	3.2	8.3	11.0	-2.6	-3.3	0.7	2.4	-3.3	-3.2	-3.2	-3.1	-3.1
Cardiovascular Disease	0.2	0.8	1.8	0.0	1.2	-1.3	0.5	-0.1	-0.5	1.0	1.3	0.6
Hypothyroidism (self reported)	2.3	5.2	7.8	1.5	2.8	-1.6	-1.4	2.8	1.9	2.7	2.7	2.5
Respiratory disease	0.6	1.4	2.0	-1.1	-1.4	0.5	1.2	-0.9	-1.1	-1.3	-1.4	-1.3
Type 2 Diabetes (T2D) (2018)	1.8	3.3	7.2	-0.5	-2.1	1.2	0.1	-2.1	-1.2	-2.7	-2.2	-2.4
Lung FEV1/FVC ratio	0.2	0.8	4.8	-0.8	-0.4	1.0	0.1	2.2	0.6	0.2	0.1	0.4
Lung FVC	0.0	0.2	1.1	-0.4	-1.1	0.3	0.4	0.2	0.2	0.1	-0.3	0.1
Neuroticism	1.1	2.5	9.1	1.0	2.4	0.7	-0.7	0.2	-0.3	1.9	3.0	1.5
Chronotype (morning person)	0.2	0.5	1.7	-1.3	0.1	-1.0	0.7	0.5	0.8	0.1	-0.1	0.5
Hair Pigment	0.0	0.4	1.1	-1.0	-0.0	0.6	0.5	1.1	0.6	0.4	0.7	0.4
Tanning	0.1	0.9	1.6	-0.6	-0.9	-0.2	0.7	-0.9	-1.1	-1.2	-1.1	-1.3
Hand grip strength (left)	6.3	16.5	36.4	3.5	3.8	0.7	-3.5	6.0	4.7	4.0	4.0	4.2
Number of treatments/medications taken	0.7	1.2	2.9	0.8	1.5	-1.7	-0.5	0.1	0.5	1.3	1.3	1.1
Average weekly spirits intake	0.7	0.8	2.8	0.9	0.4	-0.7	-0.9	1.7	1.5	0.2	-0.3	0.4
Sensitivity / hurt feelings	2.5	4.2	9.0	2.1	2.8	0.1	-1.6	1.5	1.1	2.4	3.0	2.2
Frequency of depressed mood in last 2 weeks	0.3	0.5	1.3	0.1	1.0	-0.7	0.0	0.5	0.0	0.9	1.1	0.8
Hearing difficulty/problems: Yes	0.7	1.1	2.7	-1.2	-0.0	-1.6	1.6	-0.9	-1.5	0.4	0.2	0.1
Relative age of first facial hair	1.9	3.8	6.1	-2.4	-2.5	1.6	1.9	-1.3	-1.5	-2.1	-1.9	-2.0
Other serious medical condition/disability diagnosed by doctor	1.6	2.0	3.2	-1.4	-1.6	-0.1	1.4	-1.2	-1.8	-1.5	-1.6	-1.6
Ever used hormone-replacement therapy (HRT)	0.4	0.5	1.3	0.6	1.0	0.2	-0.3	1.2	0.8	0.8	0.5	0.7
Ever had hysterectomy (womb removed)	0.7	0.8	2.2	0.9	1.2	-0.4	-0.5	0.7	0.3	1.1	1.5	0.9
Systolic blood pressure, automated reading	1.4	4.2	6.6	2.6	2.4	-0.2	-2.1	1.6	1.9	2.2	2.2	2.2
Eye problems/disorders: Diabetes related eye disease	5.3	5.9	7.8	-2.8	-2.7	-0.2	2.6	-2.1	-2.3	-2.7	-2.7	-2.5
Angina	1.0	1.4	3.6	0.6	1.5	-1.9	-0.3	1.1	1.0	1.2	1.1	1.1
Medication for hormone replacement therapy	0.7	0.8	3.5	-0.1	-0.0	1.6	-0.0	1.9	0.8	0.5	-0.3	0.5
Vitamin and mineral supplements	0.5	0.7	1.8	1.4	0.1	-0.1	-1.1	1.1	1.2	0.3	-0.2	0.6
Supplements: Zinc	0.1	0.1	0.4	-0.3	0.2	-0.0	0.3	0.1	-0.6	0.6	0.5	0.3
Medication: Co-codamol	0.1	0.2	0.8	0.9	0.1	-0.0	-0.8	0.1	-0.1	0.2	0.2	0.0
Medication: Metformin	4.2	5.9	10.9	-1.6	-2.2	-0.7	1.5	-3.0	-2.6	-3.3	-2.7	-3.1
Diabetes (father)	0.3	0.3	2.0	-0.4	0.5	-1.4	0.7	0.2	-0.3	0.2	0.1	0.0
Diabetes (mother)	0.7	0.9	1.5	0.9	1.1	0.9	-1.2	1.0	0.4	0.9	0.9	1.0
Severe depression (siblings)	0.5	0.5	1.9	0.1	0.5	-1.4	0.3	-1.3	-0.6	0.2	0.4	-0.1
Pack years adult smoking proportion	0.1	0.2	1.2	0.2	0.2	-0.5	-0.0	1.1	0.1	-0.3	-0.4	-0.3
Impedance of leg (right)	0.4	1.8	6.1	0.8	1.1	2.5	-1.4	0.7	0.9	1.2	1.5	1.3
Leg fat-free mass (left)	0.2	1.0	4.4	0.9	0.1	-0.3	-1.2	1.6	2.1	0.2	-0.1	0.4
Trunk fat percentage	3.1	12.5	20.4	-3.4	-4.1	1.5	2.6	-3.2	-3.1	-4.5	-3.9	-4.5
Hand grip strength (right)	4.5	12.2	24.8	3.3	3.0	0.6	-3.4	5.0	4.5	3.3	2.9	3.6
Townsend deprivation index at recruitment	3.2	4.6	6.7	2.4	2.4	0.6	-2.6	2.2	2.5	2.0	2.1	1.9
Current tobacco smoking	1.9	3.1	6.7	0.9	2.6	-2.0	-0.6	2.3	1.4	1.6	2.1	1.3
Average weekly fortified wine intake	3.0	3.6	7.2	-2.7	-1.8	0.3	2.3	-1.5	-2.1	-1.8	-1.6	-1.9
Maternal smoking around birth	1.1	1.6	5.7	1.1	1.2	-2.4	-0.7	1.7	1.4	0.7	0.4	0.5
Fed-up feelings	0.7	1.3	2.9	-0.9	-1.0	1.3	0.9	-1.1	-1.7	-1.2	-0.5	-1.4
Frequency of unenthusiasm / disinterest in last 2 weeks	0.4	0.5	1.9	-1.0	-0.6	-0.8	1.4	-0.1	-0.6	-0.4	-0.3	-0.5
Relative age voice broke	0.8	1.3	2.7	-1.4	-1.6	1.1	0.9	0.0	-0.8	-1.3	-1.2	-1.1
Taking other prescription medications	0.1	0.1	0.5	-0.2	-0.1	-0.3	0.2	-0.4	-0.7	-0.0	-0.1	-0.1
Age when periods started (menarche)	1.4	3.5	8.3	-2.9	-1.5	0.5	2.9	-0.9	-1.8	-1.8	-1.4	-1.7
Bilateral oophorectomy (both ovaries removed)	1.4	1.6	3.6	1.6	1.3	-1.9	-0.9	1.1	0.9	1.3	1.0	1.1
Heel bone mineral density (BMD) T-score, automated (left)	1.8	4.2	6.7	-1.7	-2.1	1.9	1.2	-2.0	-1.8	-2.6	-2.1	-2.6
Tinnitus: Yes, but not now, but have in the past	2.8	3.0	4.1	1.5	2.0	-1.1	-1.5	1.7	2.0	2.0	1.8	1.8
Qualifications: CSEs or equivalent	0.2	0.3	2.2	0.4	0.2	-1.5	0.1	0.6	0.4	-0.0	0.0	-0.1
Serious illness, injury or assault to yourself	1.1	1.4	4.2	-0.7	-1.3	1.1	0.4	-2.1	-0.9	-1.1	-1.2	-1.1
High blood pressure	0.5	1.5	3.6	-0.2	1.6	-1.3	0.5	-0.2	-0.2	1.8	1.9	1.3
Hayfever, allergic rhinitis or eczema	3.1	6.7	9.8	-2.7	-3.0	0.4	2.7	-3.1	-3.0	-2.5	-2.5	-2.4
Multivitamins +/- minerals	0.3	0.4	1.0	-0.8	0.4	0.3	0.5	-0.8	-1.0	0.2	0.7	-0.2
Stomach or abdominal pain in last month	0.2	0.3	1.0	0.2	0.1	0.7	-0.4	1.0	0.2	0.6	0.5	0.4
Supplements: Glucosamine	0.2	0.3	0.8	-0.2	0.7	-0.8	0.4	0.9	-0.1	0.6	0.5	0.3
Diverticular disease/diverticulitis (self-reported)	0.8	1.0	2.3	-0.2	-0.6	-0.4	0.4	-1.1	-0.7	-1.5	-1.3	-1.5
Medication: Atenolol	0.9	1.2	3.6	0.3	1.7	-0.7	-0.2	0.4	-0.1	1.4	1.9	1.2
Medication: Levothyroxine sodium	1.2	2.0	3.6	1.2	1.9	-1.9	-1.0	1.1	0.9	1.3	1.8	1.3
Sitting height	2.1	14.7	29.1	4.3	3.5	-1.0	-4.2	3.2	5.4	3.9	3.2	4.2
Chronic bronchitis/emphysema (father)	1.5	1.7	3.3	1.5	1.2	1.3	-1.6	1.3	1.8	1.0	0.7	1.0
High blood pressure (mother)	1.7	2.4	4.2	1.7	1.3	-0.5	-1.9	0.5	1.7	2.0	1.4	2.0
Body mass index (BMI)	2.5	10.5	18.3	-2.6	-4.2	0.5	2.3	-2.3	-2.4	-4.3	-4.2	-4.1
Impedance of leg (left)	0.4	1.8	5.8	0.5	1.2	2.4	-1.2	0.2	0.5	1.3	1.7	1.3
Leg predicted mass (left)	0.2	1.0	4.4	0.9	0.1	-0.3	-1.2	1.5	2.1	0.2	-0.1	0.4
Trunk fat mass	1.6	7.0	13.0	-2.5	-3.3	1.3	1.6	-1.9	-1.7	-3.6	-3.2	-3.5
Waist circumference	0.6	2.0	4.1	-1.2	-1.8	0.8	0.8	-0.5	-1.1	-2.0	-1.7	-2.0
Number of incorrect matches in round	2.6	4.4	7.9	1.3	2.5	-0.3	-1.2	2.6	1.9	2.6	2.2	2.8
Past tobacco smoking	0.6	1.0	2.6	-0.1	-1.5	1.5	-0.3	-0.7	0.0	-1.2	-1.6	-0.6
Alcohol usually taken with meals	0.6	1.0	2.6	-0.8	-1.1	-0.5	0.7	-1.6	-1.0	-1.1	-0.9	-1.1
Nervous feelings	1.1	2.0	5.6	1.3	2.4	-0.3	-0.8	0.1	0.0	1.7	2.2	1.5
Frequency of tenseness / restlessness in last 2 weeks	0.5	0.7	2.1	-0.3	-0.4	-1.0	0.9	-0.9	-1.4	-0.8	-0.2	-0.8
Hearing difficulty/problems with background noise	1.2	1.9	5.1	-1.6	-1.1	0.1	1.7	-1.8	-2.2	-0.8	-0.7	-1.1
Hair/balding pattern: Pattern 2	1.1	1.5	2.5	-1.5	-1.5	-0.4	1.6	-0.9	-0.7	-1.3	-1.2	-1.3
Had menopause	1.2	1.5	2.2	-0.7	-1.2	-1.1	1.4	-0.7	-1.3	-1.4	-1.4	-1.5
Had other major operations	0.2	0.2	0.6	0.5	-0.6	-0.3	-0.4	-0.8	0.2	-0.2	-0.4	-0.3
Forced vital capacity (FVC)	1.6	6.3	14.3	2.3	1.1	1.4	-2.7	3.2	3.8	2.4	1.7	2.7
Heel bone mineral density (BMD) T-score, automated (right)	1.9	4.3	6.4	-1.8	-2.2	1.9	1.4	-2.1	-2.0	-2.5	-2.0	-2.5
Ever unenthusiastic/disinterested for a whole week	2.0	2.5	3.3	1.8	1.7	0.4	-1.7	1.3	1.4	1.7	1.8	1.7
Qualifications: None of the above	2.0	4.3	11.0	2.2	1.9	-0.3	-1.9	3.3	2.3	1.8	2.0	1.8
Financial difficulties in last 2 years	0.4	0.5	1.2	-0.2	-1.1	0.5	0.5	-0.7	-0.1	-0.8	-1.0	-0.7
Mouth/teeth dental problems	1.0	1.5	4.5	1.2	-0.0	0.8	-1.3	2.1	1.8	0.7	-0.1	1.1
Heart attack	0.1	0.1	0.2	0.3	-0.1	0.3	0.1	0.4	-0.4	0.1	-0.0	0.1
Allergy	3.6	8.4	11.8	3.1	3.1	0.1	-3.3	2.6	3.4	2.9	3.0	3.0
Pain all over the body in last month	0.1	0.1	0.3	-0.4	-0.2	-0.4	0.3	-0.0	-0.2	-0.5	-0.3	-0.4
Diabetes (self-reported)	3.4	5.3	9.3	-1.6	-2.4	0.7	1.5	-2.6	-2.2	-3.0	-2.6	-3.0
Hayfever/allergic rhinitis (self-reported)	2.7	3.5	6.9	-2.6	-1.6	-0.1	2.6	-1.4	-2.1	-1.8	-1.9	-1.7
Medication: Ramipril	0.3	0.4	0.7	-0.8	-0.3	-0.7	0.7	-0.8	-0.8	-0.3	-0.5	-0.3
Medication: Simvastatin	1.4	2.0	4.2	-1.4	-0.9	0.1	1.3	-2.0	-1.7	-1.6	-1.2	-1.7
Fluid intelligence score	2.5	5.2	7.5	-2.0	-2.7	1.1	1.7	-2.7	-1.8	-2.5	-2.7	-2.6
Illnesses of siblings	0.5	0.7	1.6	-0.1	-0.8	-0.5	0.2	-1.3	-0.7	-1.2	-0.9	-1.2
Neuroticism score	0.4	0.8	3.0	0.4	1.3	-0.0	0.2	-0.1	-1.1	0.8	1.7	0.4
Weight	0.3	1.4	3.4	-0.5	-1.8	0.6	-0.0	-0.1	0.3	-1.8	-1.8	-1.6
Impedance of arm (right)	0.3	1.2	4.0	-1.4	0.2	1.1	1.0	-1.3	-2.0	-0.5	0.5	-0.8
Arm fat percentage (right)	3.2	12.6	22.1	-3.2	-4.2	0.9	2.6	-2.6	-3.3	-4.7	-4.1	-4.7
Trunk fat-free mass	1.4	7.9	17.2	2.8	2.4	-0.8	-2.9	3.6	4.2	2.6	2.0	2.9
Hip circumference	1.3	5.4	9.9	-2.0	-3.1	1.4	1.3	-1.5	-1.6	-3.1	-2.9	-3.0
Time employed in main current job	1.5	1.7	2.4	1.2	1.5	0.5	-1.0	1.4	1.5	1.4	1.3	1.5
Alcohol intake versus 10 years previously	0.2	0.3	1.1	0.1	0.1	0.2	0.2	0.4	1.0	0.6	0.3	0.7
Father’s age at death	0.6	0.9	2.7	-1.2	-0.8	0.6	1.0	-0.8	-1.7	-0.7	-0.5	-0.7
Worrier / anxious feelings	1.3	2.4	6.5	1.2	2.1	0.3	-0.9	0.3	0.6	2.1	2.5	2.0
Frequency of tiredness / lethargy in last 2 weeks	0.3	0.6	1.4	-0.5	-0.9	0.2	0.8	0.2	-0.6	-1.0	-0.6	-1.2
Falls in the last year	0.3	0.4	1.2	-0.2	-0.6	0.2	0.3	-1.1	-0.9	-0.5	-0.6	-0.7
Hair/balding pattern: Pattern 3	0.2	0.3	1.7	-0.4	-0.4	0.2	0.2	-1.3	-0.5	-0.3	-0.3	-0.3
Number of live births	6.5	9.3	14.4	-3.1	-3.8	0.6	2.8	-2.6	-2.7	-3.5	-3.6	-3.4
Forced expiratory volume in 1-second (FEV1)	1.7	5.9	14.2	2.2	0.6	1.8	-2.7	3.5	3.8	1.9	1.2	2.3
Pulse rate	1.1	1.8	5.4	-0.4	-0.7	-0.7	0.7	-2.3	-1.5	-1.6	-1.1	-1.8
Happiness	0.5	0.7	2.7	0.0	-0.9	0.3	-0.2	-1.6	0.0	-0.8	-1.0	-0.8
Noisy workplace	1.2	1.4	2.9	-1.2	-1.4	0.1	1.2	-0.2	-0.9	-1.5	-1.7	-1.5
Qualifications: A levels/AS levels or equivalent	1.3	2.9	4.3	-2.1	-1.6	-0.7	1.7	-1.8	-2.0	-1.6	-1.9	-1.5
Serious illness, injury or assault of a close relative in last 2 years	0.3	0.3	0.8	0.4	0.3	0.4	-0.2	-0.2	0.1	0.9	0.8	0.8
Mouth/teeth dental problems: Dentures	0.2	0.4	1.2	0.1	1.0	-0.2	0.2	-1.1	-0.8	0.3	0.9	-0.1
Asthma	0.8	1.5	2.6	-1.2	-1.6	0.4	1.4	-0.6	-1.2	-1.3	-1.6	-1.3
Medication: Ibuprofen (e.g. Nurofen)	0.6	0.8	2.4	1.6	0.2	-0.9	-1.3	0.3	1.3	-0.3	-0.3	-0.0
Medication: Cholesterol lowering	0.0	0.0	0.1	-0.0	0.4	-0.3	-0.0	0.1	0.4	0.0	-0.2	-0.0
Depression (self-reported)	0.2	0.3	0.7	0.8	0.4	0.6	-0.7	-0.0	0.5	0.2	0.5	0.2
Medication: Lansoprazole	1.7	1.9	3.9	2.0	1.8	-1.1	-1.6	1.5	1.2	0.8	1.1	0.8
Prospective memory result	3.1	3.8	7.4	1.2	1.8	1.0	-1.5	1.9	1.9	2.5	2.3	2.7
Lung cancer (father)	0.7	0.8	1.9	1.2	1.4	0.4	-1.1	-0.0	0.4	0.9	1.1	0.7
Illnesses of mother	1.1	1.3	3.1	-0.5	-1.0	0.3	0.7	-1.5	-0.5	-1.7	-1.4	-1.6
Forced expiratory volume in 1-second (FEV1), Best measure	0.8	2.6	7.3	1.4	0.3	0.9	-1.8	2.5	2.7	1.0	0.6	1.4
Pulse wave Arterial Stiffness index	0.3	0.3	1.1	0.4	0.7	-1.1	-0.2	0.5	-0.3	0.5	0.4	0.6
Impedance of arm (left)	0.4	1.8	5.0	-1.8	0.0	1.2	1.3	-1.9	-2.2	-0.7	0.3	-0.9
Arm fat mass (right)	1.6	6.7	13.2	-2.0	-3.3	1.0	1.5	-1.6	-1.8	-3.6	-3.3	-3.5
Trunk predicted mass	1.4	7.8	17.1	2.7	2.4	-0.7	-2.8	3.5	4.1	2.6	2.0	2.8
Standing height	2.1	20.6	32.0	3.9	4.7	0.8	-4.6	4.7	5.7	4.9	4.7	5.1
Length of working week for main job	0.8	0.9	3.8	-0.1	-0.8	2.0	-0.6	0.3	-0.0	-1.1	-1.0	-0.8
Exposure to tobacco smoke at home	1.4	1.6	2.8	1.7	1.2	-1.5	-1.4	0.9	1.4	1.0	0.6	1.1
Breastfed as a baby	1.0	1.3	2.7	1.5	0.5	-0.1	-1.3	1.4	1.7	0.9	0.5	1.1
Tense / ‘highly strung’	1.5	2.5	4.9	1.3	2.2	-2.0	-0.7	1.5	0.8	1.8	1.9	1.6
Seen doctor (GP) for nerves, anxiety, tension or depression	2.0	3.1	4.8	1.7	2.2	-1.0	-1.4	1.2	1.6	2.2	2.2	1.9
Hair/balding pattern: Pattern 4	4.8	11.6	16.1	2.8	3.4	1.0	-3.2	4.0	3.4	4.0	3.9	3.9
Birth weight of first child	0.1	0.2	0.9	-0.3	0.0	-0.7	0.3	-0.9	-0.1	-0.1	-0.0	-0.2
Peak expiratory flow (PEF)	2.8	6.5	11.8	2.4	1.6	1.9	-3.0	3.1	3.4	2.3	2.1	2.6
Pulse wave reflection index	0.3	0.4	1.0	-0.3	-0.1	0.4	-0.3	0.9	0.8	0.7	0.2	1.0
Ever highly irritable/argumentative for 2 days	0.5	0.6	2.0	0.8	-0.2	-1.4	-0.5	1.1	1.1	-0.0	-0.5	0.1
Loud music exposure frequency	1.3	1.4	4.5	-0.4	-1.7	-0.4	0.6	-0.1	-0.5	-1.5	-2.1	-1.4
Qualifications: O levels/GCSEs or equivalent	0.9	1.5	2.6	-1.5	-0.9	-0.4	1.2	-1.4	-1.6	-1.1	-1.2	-1.1
Mouth/teeth dental problems: Bleeding gums	1.4	1.8	3.2	-1.7	-1.0	-0.1	1.5	-1.8	-1.5	-1.3	-1.0	-1.5
Blood clot in the leg (DVT)	0.1	0.2	0.9	0.0	-0.5	1.0	-0.1	-0.2	-0.4	-0.0	-0.2	-0.3
Medication: Paracetamol	0.6	1.0	2.4	1.6	0.7	-0.1	-1.2	0.5	1.1	1.0	0.9	1.0
Headache pain in last month	3.5	6.1	12.0	-1.9	-2.4	-1.0	2.6	-3.5	-2.6	-2.6	-2.1	-2.7
Medication for cholesterol, blood pressure or diabetes	0.1	0.2	0.4	0.4	-0.5	0.6	-0.6	0.3	-0.0	-0.3	-0.1	-0.2
Glaucoma (self-reported)	3.1	3.7	8.0	-1.5	-2.6	-0.2	1.5	-1.3	-1.1	-2.4	-2.8	-2.3
Gout (self-reported)	0.2	0.3	1.1	0.0	-0.7	-0.6	0.0	-1.0	-0.3	-0.3	-0.6	-0.2
Hypothyroidism/myxoedema (self-reported)	0.8	1.6	2.9	0.8	1.7	-1.7	-0.6	1.2	0.6	1.4	1.6	1.2
Medication: Amlodipine	0.4	0.5	1.9	-0.9	0.6	-1.4	1.0	-0.1	-0.4	0.3	0.6	0.2
Medication: Ventolin 100micrograms inhaler	1.4	1.8	3.1	-1.6	-1.8	-0.0	1.6	-0.8	-1.4	-1.2	-1.5	-1.2
Birth weight	0.3	0.6	3.0	-0.3	-0.0	0.1	-0.2	1.7	1.3	0.5	0.2	0.6
Chronic bronchitis/emphysema (mother)	2.5	3.0	5.4	1.6	1.9	-0.1	-1.6	1.5	2.3	1.9	1.7	1.8
High blood pressure (siblings)	2.8	4.1	7.2	1.3	2.1	0.4	-1.5	2.7	2.3	2.4	1.9	2.5
Forced vital capacity (FVC), Best measure	1.0	3.5	8.9	1.9	0.8	0.6	-2.1	2.5	3.0	1.6	1.1	1.9
Body fat percentage	3.2	12.5	21.2	-3.2	-4.2	1.6	2.4	-3.0	-3.0	-4.6	-4.0	-4.5
Leg fat percentage (right)	2.3	8.3	15.5	-2.3	-3.7	1.3	1.5	-2.1	-2.0	-3.9	-3.6	-3.7
Arm fat-free mass (right)	0.9	4.4	13.6	2.1	1.2	-0.2	-2.4	2.7	3.7	1.5	0.9	1.9
Exposure to tobacco smoke outside home	1.4	1.8	5.5	1.6	0.6	0.6	-1.4	2.3	2.1	0.6	0.4	0.8
Comparative body size at age 10	1.5	4.1	5.9	-1.9	-2.4	0.3	1.5	-1.8	-2.4	-2.4	-2.2	-2.3
Number of full brothers	0.2	0.3	0.9	-0.7	-0.4	1.0	0.7	0.2	-0.0	0.3	-0.2	0.3
Worry too long after embarrassment	0.4	0.8	3.4	0.1	0.7	-0.0	0.1	-1.8	-1.5	0.1	0.8	-0.3
Seen a psychiatrist for nerves, anxiety, tension or depression	3.8	4.9	8.3	1.9	2.9	-1.0	-1.4	2.6	1.5	2.7	2.5	2.6
Wheeze or whistling in the chest in last year	0.5	0.9	2.3	-1.1	-0.6	-1.5	1.4	0.3	-0.6	-0.4	-0.9	-0.6
Number of children fathered	1.1	1.2	4.6	-1.3	-0.1	-2.2	1.2	-0.9	-1.1	-0.4	-0.5	-0.6
Reason for reducing amount of alcohol drunk: Health precaution	0.6	0.7	2.4	-1.1	0.2	-0.3	1.6	-0.1	-1.1	0.8	0.4	0.4
Age at first live birth	0.2	0.3	2.1	0.0	0.4	-1.5	0.2	-0.7	0.3	0.0	-0.2	0.3
Pulse wave peak to peak time	0.2	0.3	1.4	-0.3	-0.6	1.2	0.1	-0.3	0.5	-0.3	-0.2	-0.4
Health satisfaction	0.4	0.5	1.1	1.0	0.7	-0.6	-0.9	-0.2	0.3	0.8	0.8	0.7
Shortness of breath walking on level ground	1.2	1.4	2.4	-0.5	-1.6	-0.8	0.6	-1.1	-1.3	-1.3	-1.5	-1.4
Qualifications: College or University degree	2.6	8.3	16.8	-2.8	-3.1	0.5	2.4	-4.1	-3.3	-2.8	-3.0	-2.7
Eye problems/disorders: None of the above	0.9	1.1	2.6	1.0	1.4	-1.6	-0.8	0.0	0.7	0.8	1.1	0.9
Mouth/teeth dental problems: Loose teeth	1.3	1.6	3.9	-0.8	-1.8	-0.6	1.1	0.7	-0.3	-1.3	-2.0	-1.5
Emphysema/chronic bronchitis	1.1	1.3	3.0	1.0	1.4	-1.6	-0.5	1.7	1.0	0.8	0.8	0.8
Medication for pain relief, constipation, heartburn	0.2	0.3	1.0	-1.0	0.1	0.1	0.9	0.8	-0.3	0.3	0.2	0.3
Neck or shoulder pain in last month	1.7	2.4	5.5	2.4	1.3	-0.8	-2.0	1.6	1.3	1.4	1.4	1.3
Medication: Blood pressure	0.3	0.4	1.5	-1.2	0.3	-0.2	1.1	-0.9	-0.4	0.4	0.2	0.2
Angina (self-reported)	1.1	1.4	5.2	0.5	1.5	-2.3	-0.1	1.0	0.9	1.2	1.0	1.1
Migraine (self-reported)	1.4	1.8	3.8	-1.7	-1.6	0.4	1.4	-1.4	-0.3	-1.1	-2.0	-1.0
Medication: Ibuprofen	0.6	0.7	1.8	1.3	-0.1	-0.9	-1.1	0.4	1.3	-0.5	-0.6	-0.3
Medication: Allopurinol	0.5	0.7	2.8	0.6	0.6	-1.7	-0.5	-0.1	0.6	0.8	0.4	0.9
Medication: Omeprazole	0.9	1.1	2.2	-0.9	-1.5	0.9	0.5	-1.3	-0.4	-1.1	-1.2	-1.1
Medication: Seretide 50 evohaler	0.6	0.7	2.3	-0.3	0.8	-1.5	0.5	-0.3	-0.3	1.0	1.0	1.0
Mean time to correctly identify matches	1.2	2.2	4.5	-1.3	-1.1	-1.9	1.9	-2.1	-2.0	-0.5	-0.8	-0.9
Heart disease (mother)	0.4	0.5	2.9	-0.3	0.4	-1.7	0.7	0.5	-0.3	0.7	0.3	0.4
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.2	0.3	1.4	-0.1	-0.4	0.8	-0.0	1.2	0.2	0.2	0.3	0.2
Whole body fat mass	1.5	6.4	12.2	-2.2	-3.2	1.3	1.4	-1.8	-1.7	-3.5	-3.1	-3.3
Leg fat mass (right)	1.6	6.0	11.8	-1.8	-3.4	1.5	1.0	-1.5	-1.1	-3.4	-3.3	-3.2
Arm predicted mass (right)	0.7	3.8	11.4	2.1	1.1	-0.3	-2.3	2.5	3.4	1.4	0.8	1.7
Pulse rate, automated reading	2.4	7.8	13.8	-2.1	-2.2	-0.5	2.1	-3.7	-3.3	-3.5	-2.6	-3.5
Alcohol intake frequency.	0.3	0.6	1.6	1.3	0.4	0.5	-1.0	0.7	1.3	0.2	0.4	0.5
Comparative height size at age 10	1.8	9.9	17.5	3.0	2.8	0.6	-3.3	3.6	4.2	3.3	2.8	3.5
Number of full sisters	0.4	0.5	3.6	-0.0	0.1	1.9	-0.2	0.2	0.2	0.4	0.7	0.4
Suffer from ‘nerves’	2.9	4.5	9.6	2.0	3.1	-0.9	-1.4	1.5	0.9	2.6	2.9	2.4
Overall health rating	0.5	1.1	2.5	-1.0	-0.9	0.2	0.9	-0.9	-1.3	-1.3	-0.7	-1.6
Chest pain or discomfort	0.8	1.2	2.2	-1.2	-1.4	-0.1	1.5	-0.1	-0.4	-1.1	-1.4	-1.2
Had major operations	0.8	0.9	1.6	-0.7	-0.2	-1.3	0.6	-1.3	-1.1	-1.1	-0.8	-1.1
Age at last live birth	0.3	0.4	1.7	-0.8	0.0	-1.3	0.9	-0.3	0.2	-0.2	-0.5	0.0
Family relationship satisfaction	0.4	0.5	2.8	0.6	0.2	0.5	-0.7	-1.7	0.3	0.6	0.5	0.5
Leg pain on walking	0.7	0.9	1.8	-0.7	-1.3	0.4	0.7	-0.7	-0.9	-1.1	-1.3	-1.1
Qualifications: NVQ or HND or HNC or equivalent	1.0	1.2	2.0	1.3	1.2	-1.2	-1.2	1.4	1.4	0.5	0.6	0.6
Commuting to job workplace: Car/motor vehicle	0.1	0.2	1.2	-0.1	0.2	-0.4	0.1	1.1	0.2	-0.1	-0.1	0.1
Illness, injury, bereavement, stress in last 2 years	0.1	0.1	0.2	0.1	0.3	-0.4	-0.0	0.5	-0.4	-0.2	0.2	-0.1
Medication: Aspirin	1.4	1.8	3.6	-0.8	-0.8	-1.9	1.1	-1.7	-1.7	-1.2	-1.0	-1.5
Supplements: Vitamin C	0.5	0.6	1.1	-1.0	-0.9	-0.8	0.9	-0.0	-0.6	-0.5	-1.0	-0.5
Knee pain experienced in last month	0.2	0.3	0.8	0.0	-0.6	0.3	0.1	-0.1	-0.3	-0.8	-0.5	-0.9
Hypertension (Self-reported)	0.7	2.0	5.0	0.4	1.8	-1.3	0.0	0.2	0.2	2.2	2.2	1.7
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.1	0.1	0.4	-0.1	0.3	-0.1	0.3	0.1	0.6	0.0	0.2	0.1
Illnesses of father: Heart disease	3.9	5.3	7.3	2.3	2.4	0.5	-2.4	2.2	2.2	2.7	2.5	2.7
Illnesses of siblings: Diabetes	0.2	0.2	1.5	-0.5	-0.4	1.2	0.3	0.1	-0.3	0.1	0.1	0.0
Smoking status: Previous	0.3	0.5	2.0	-0.1	1.0	-0.2	0.3	-0.4	-0.2	0.9	1.4	0.4
Forced expiratory volume in 1-second (FEV1), predicted	1.9	4.0	8.2	1.4	1.6	2.1	-2.2	2.5	2.9	1.4	1.7	1.8
Whole body fat-free mass	0.7	4.3	11.8	2.1	1.4	-0.7	-2.3	2.7	3.4	1.6	1.1	1.9
Leg fat-free mass (right)	0.2	1.2	4.4	1.1	0.5	-0.7	-1.2	1.5	2.1	0.6	0.3	0.7
Arm fat percentage (left)	3.6	14.3	24.6	-3.5	-4.3	0.8	2.9	-3.0	-3.5	-5.0	-4.4	-4.9
Average weekly red wine intake	0.7	1.0	3.1	-1.8	-1.1	0.0	1.4	-0.1	-1.1	-0.7	-0.9	-0.6
Handedness (chirality/laterality): Left-handed	1.5	1.8	3.1	1.3	0.6	1.8	-1.5	1.5	1.7	1.0	1.2	1.1
Mood swings	0.2	0.4	1.9	-0.5	0.3	0.2	0.9	-0.0	-1.4	-0.2	0.6	-0.5
Loneliness, isolation	0.7	1.0	3.4	-0.8	-0.5	0.9	0.7	-1.8	-1.2	-0.8	-0.3	-1.0
Long-standing illness, disability or infirmity	0.2	0.3	1.5	0.3	-0.7	-0.1	-0.4	-1.2	-0.5	-0.3	-0.5	-0.5
Ever had bowel cancer screening	0.5	0.6	1.6	-0.2	1.2	-1.3	0.3	0.4	-0.0	0.8	1.0	0.8
Diabetes diagnosed by doctor	4.1	6.7	12.2	-1.8	-2.5	-0.0	1.7	-2.9	-2.6	-3.5	-2.9	-3.4
Ever had stillbirth, spontaneous miscarriage or termination	0.4	0.4	1.2	0.1	-1.0	0.8	-0.2	-0.1	0.7	-0.2	-1.1	-0.2
Friendships satisfaction	1.6	2.0	9.0	-0.4	-1.2	1.0	0.4	-3.0	-1.0	-1.3	-1.2	-1.4
Qualifications: nursing, teaching	0.9	1.4	4.0	-0.6	-1.1	-1.6	0.6	-2.0	-0.9	-1.0	-1.1	-0.9
Commuting to job workplace: Walk	1.0	1.0	2.2	1.3	1.5	-0.2	-1.1	-0.1	0.9	1.0	1.2	0.9
Eye problems/disorders: Cataract	0.5	0.6	1.4	0.5	0.7	0.9	-0.6	1.0	-0.2	0.9	1.2	0.6
Mouth/teeth dental problems: Mouth ulcers	0.1	0.2	1.7	-0.2	0.1	-1.3	0.4	0.4	-0.1	-0.1	-0.1	-0.1
Medication for cholesterol	0.1	0.2	0.5	0.3	-0.5	0.6	-0.5	0.0	0.7	-0.2	-0.4	0.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.5	0.6	1.2	-1.0	-0.2	-1.1	1.1	-1.0	-1.0	0.1	0.1	-0.1
Back pain experienced in last month	2.5	3.6	9.2	3.0	1.8	-0.9	-2.8	1.1	2.0	1.4	1.5	1.3
Mineral and other dietary supplements	2.3	3.1	5.6	-1.5	-2.4	0.1	1.7	-1.7	-1.5	-2.0	-2.2	-1.8
Breast cancer (self-reported)	0.4	0.5	3.4	-0.1	-0.1	0.2	0.3	-1.8	-0.7	-0.2	-0.1	-0.4
Asthma (self-reported)	1.0	2.0	3.2	-1.5	-1.8	0.3	1.7	-0.6	-1.3	-1.5	-1.7	-1.4
Osteoporosis (self-reported)	0.5	0.6	1.8	1.3	0.6	-1.2	-0.8	-0.4	0.8	0.4	0.5	0.3
Osteoarthritis (self-reported)	0.9	1.2	2.6	-0.6	-0.9	-1.3	0.7	-1.6	-1.1	-1.0	-1.3	-1.1
Medication: Aspirin	1.1	1.4	5.3	-0.4	-0.4	-2.3	0.9	-1.2	-1.6	-0.9	-0.7	-1.1
Medication: Gliclazide	0.8	0.9	2.1	0.3	-0.6	-0.8	-0.4	-1.2	-0.5	-1.5	-1.2	-1.2
Illnesses of father: None of the above (group 1)	1.1	1.3	2.9	-1.1	-1.2	0.8	1.1	-1.7	-1.2	-1.0	-0.8	-1.1
Smoking status: Current	1.9	3.0	6.1	0.8	2.5	-2.0	-0.4	2.3	1.4	1.6	2.1	1.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.5	1.1	1.9	0.7	0.4	1.3	-1.2	0.9	1.1	1.3	1.0	1.4
Whole body water mass	0.8	4.5	11.8	2.2	1.5	-0.7	-2.3	2.8	3.4	1.6	1.1	1.9
Leg predicted mass (right)	0.2	1.3	4.7	1.1	0.6	-0.8	-1.3	1.6	2.2	0.6	0.3	0.8
Arm fat mass (left)	1.8	7.5	14.4	-2.3	-3.4	0.9	1.8	-1.8	-2.0	-3.8	-3.5	-3.6
Number of self-reported non-cancer illnesses	0.3	0.6	1.4	-0.8	0.1	-1.2	1.1	-1.2	-0.6	-0.0	-0.3	-0.3
Average weekly champagne plus white wine intake	2.4	3.3	5.2	-1.8	-2.1	0.7	1.5	-2.3	-1.7	-2.0	-1.9	-1.9
Miserableness	0.4	0.6	2.2	-0.2	-0.6	1.5	0.2	-1.1	-1.2	-0.4	0.2	-0.6
Guilty feelings	0.7	1.0	3.3	-0.8	-0.7	0.2	1.2	-1.3	-1.8	-0.6	-0.1	-0.9
Wears glasses or contact lenses	1.0	1.2	4.3	-0.0	-1.0	-1.4	0.1	-2.1	-0.9	-0.7	-1.2	-0.9
Ever taken oral contraceptive pill	0.7	0.8	1.5	-0.9	-1.1	-1.1	1.2	0.1	-0.2	-0.7	-1.2	-0.7
Hearing aid user	0.9	1.1	1.7	-1.1	-1.1	-1.0	1.3	-0.6	-1.0	-0.9	-1.2	-0.8
Mother’s age at death	1.0	1.2	3.5	0.6	1.7	1.0	-0.9	0.0	0.0	1.2	1.9	0.9
Financial situation satisfaction	1.9	2.3	4.1	0.8	1.6	-0.2	-1.0	1.6	2.0	1.8	1.8	1.9
Tinnitus: Yes, now most or all of the time	0.5	0.6	1.3	-0.3	0.9	-0.1	0.2	1.1	0.0	0.9	1.0	1.0
Commuting to job workplace: Public transport	0.5	0.5	1.4	0.4	1.2	0.1	-0.7	0.6	0.4	0.7	1.1	0.7
Eye problems/disorders: Glaucoma	4.1	4.9	10.5	-2.0	-2.9	0.3	2.0	-1.1	-1.4	-2.8	-3.2	-2.5
Medication: Blood pressure	0.7	1.3	5.6	0.6	1.3	-2.4	-0.2	0.6	0.1	1.1	1.2	0.8
Pain type(s) experienced in last month: Hip pain	0.6	0.8	1.7	0.7	-1.1	0.4	-0.5	-0.4	-0.4	-1.3	-1.1	-1.2
Supplements: Fish oil (including cod liver oil)	2.8	3.6	5.9	1.9	2.4	0.2	-2.1	1.6	1.9	2.1	2.1	2.0
High cholesterol (Self-reported)	0.6	1.0	2.3	-0.7	-0.3	-1.5	1.0	-1.0	-0.9	-1.1	-0.8	-1.3
Medication: Bendroflumethiazide	3.3	4.9	7.8	2.3	1.9	-0.3	-2.5	2.5	2.8	2.4	1.8	2.5
Medication: Paracetamol	0.4	0.6	1.5	1.2	0.3	-0.1	-0.8	1.0	0.8	0.8	0.7	0.7
Medication: Lisinopril	0.4	0.5	2.4	-0.1	-0.0	-1.6	0.8	-0.5	-0.3	-0.4	-0.5	-0.5
Medication: Atorvastatin	0.9	1.2	4.0	0.9	0.9	-2.0	-0.3	1.4	1.2	0.8	0.5	0.7
Illnesses of father: High blood pressure	0.8	1.0	3.5	0.5	0.9	-1.9	-0.1	1.8	0.3	0.7	0.6	0.7
Alcohol drinker status: Never	0.1	0.1	0.4	0.2	0.2	-0.7	-0.1	0.1	0.2	-0.1	-0.1	0.1
Ever smoked	0.7	1.2	2.7	0.4	1.6	-1.6	-0.1	1.1	0.1	1.2	1.6	0.6
Basal metabolic rate	0.4	2.2	7.6	1.6	0.7	-0.3	-1.8	2.0	2.8	0.8	0.5	1.1
Leg fat percentage (left)	2.4	8.6	15.1	-2.5	-3.6	1.1	1.8	-2.5	-2.4	-3.9	-3.5	-3.8
Arm fat-free mass (left)	0.8	4.1	12.2	2.3	1.1	0.0	-2.6	2.5	3.5	1.4	0.9	1.7
Number of operations (self-reported)	0.2	0.3	2.2	-0.0	0.0	-1.5	-0.1	-0.2	0.0	-0.0	-0.3	-0.1
Average weekly beer plus cider intake	1.0	1.5	6.2	-0.9	-1.1	2.5	0.5	-0.2	-0.4	-1.2	-1.2	-1.2
Irritability	0.7	1.1	3.1	-1.3	-0.3	-1.2	1.7	-0.0	-1.8	-0.6	-0.2	-0.8
Risk taking	1.3	1.9	4.8	1.3	1.1	-0.5	-1.1	2.2	1.7	1.5	0.6	1.6
Ever had prostate specific antigen (PSA) test	0.8	0.9	2.3	-0.1	1.1	-0.8	0.2	0.7	-0.1	1.4	1.5	1.2
Fractured/broken bones in last 5 years	0.4	0.5	1.0	0.0	-1.0	0.6	-0.1	-0.3	-0.9	-0.9	-0.8	-0.9
Age started oral contraceptive pill	0.2	0.3	1.1	0.6	-0.3	-1.0	-0.1	-0.1	0.4	-0.5	-0.6	-0.4
Diastolic blood pressure, automated reading	0.8	2.4	3.5	1.7	1.7	-1.2	-1.3	0.7	1.5	1.9	1.7	1.8
Ever depressed for a whole week	5.0	6.1	9.7	3.1	1.7	0.1	-3.1	3.1	2.7	2.3	2.2	2.5
Unable to work because of sickness or disability	1.7	2.2	2.8	1.6	1.6	-1.1	-1.5	1.4	1.7	1.5	1.2	1.6
Commuting to job workplace: Cycle	1.5	1.8	4.6	-1.4	0.3	-1.5	1.6	-2.0	-2.1	-0.0	-0.2	-0.4
Myopia	0.7	1.0	4.5	-0.3	0.3	-1.1	0.5	-2.1	-1.6	-0.1	0.7	-0.5
Vascular/heart problems diagnosed by doctor	0.5	1.4	3.3	0.1	-1.7	1.5	-0.5	0.3	0.3	-1.6	-1.8	-1.2
Cholesterol lowering medication	1.6	2.4	3.7	-1.1	-1.3	-1.0	1.4	-1.8	-1.9	-1.7	-1.4	-1.9
Medication: Omeprazole (e.g. Zanprol)	0.3	0.4	1.3	-0.1	-1.0	0.5	-0.1	-0.3	0.3	-0.6	-1.1	-0.6
Pain experienced in last month	0.2	0.4	1.6	-1.3	0.3	0.4	0.8	0.7	0.0	0.4	0.2	0.4
Supplements: Calcium	0.2	0.2	0.6	0.5	0.5	-0.8	-0.3	-0.3	-0.4	0.4	0.3	0.2
Basal cell carcinoma (self-reported)	0.3	0.3	0.8	-0.9	0.5	-0.1	0.6	0.6	-0.0	0.6	0.6	0.5
Heart attack/myocardial infarction (self-reported)	0.1	0.1	0.3	0.3	-0.0	0.2	0.1	0.5	-0.5	0.2	0.1	0.1
Deep venous thrombosis (DVT) (self-reported)	0.0	0.1	0.3	0.1	-0.2	0.6	-0.1	0.0	-0.1	0.3	0.1	0.0
Heart disease (siblings)	0.1	0.2	0.4	-0.4	0.1	-0.1	0.6	0.0	-0.6	0.6	0.4	0.3
Alcohol drinker status: Previous	3.7	4.3	6.1	-2.5	-2.5	0.5	2.5	-1.6	-2.4	-1.9	-1.8	-2.1
Pack years of smoking	0.2	0.3	0.7	-0.2	-0.0	-0.8	0.4	0.7	-0.2	-0.5	-0.6	-0.6
Impedance of whole body	0.2	1.0	4.0	-0.9	0.5	2.0	0.2	-1.2	-1.2	0.1	0.9	-0.1
Leg fat mass (left)	1.4	5.5	10.5	-1.9	-3.2	1.3	1.1	-1.6	-1.2	-3.2	-3.1	-3.0
Arm predicted mass (left)	0.7	3.7	11.1	2.1	1.0	-0.0	-2.4	2.6	3.3	1.3	0.7	1.6