Hub : Genes

POLR3K

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Adrenal Gland 0.1274 0.0675 9.1e-03 -0.003 NA -0.008 NA -0.005 4.1e-01 NA 8.6e-01 NA 5.6e-01
2 GTEx Artery Tibial 0.1210 0.0576 7.8e-03 0.002 NA -0.001 NA 0.004 2.1e-01 NA 3.8e-01 NA 1.3e-01
3 GTEx Brain Cerebellar Hemisphere 0.3320 0.1000 3.0e-04 0.010 NA 0.036 NA 0.042 1.7e-01 NA 4.3e-02 NA 3.1e-02
4 METSIM Adipose 0.0899 0.0354 2.0e-04 0.012 0.024 0.026 0.026 0.023 4.7e-03 1.3e-04 6.8e-05 6.7e-05 1.7e-04
5 NTR Blood 0.0351 0.0108 2.5e-07 0.026 0.027 0.037 0.030 0.035 5.5e-09 4.2e-09 6.5e-12 4.9e-10 1.8e-11
6 YFS Blood 0.1769 0.0308 0.0e+00 0.151 0.155 0.153 0.158 0.161 5.3e-47 3.0e-48 1.2e-47 2.6e-49 3.0e-50
7 TCGA Soft Tissue Sarcoma 0.0880 0.0520 4.6e-03 -0.001 0.028 0.002 NA 0.010 3.5e-01 8.7e-03 2.2e-01 NA 7.5e-02
8 TCGA Stomach Adenocarcinoma 0.1020 0.0390 1.3e-04 0.081 0.063 0.057 NA 0.067 1.9e-06 2.5e-05 5.8e-05 NA 1.4e-05

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bipolar Disorder (2018) 0.6 0.9 3.0 -1.7 1.0 -0.8 1.6 -0.5 -0.1 -0.1 0.0
Bipolar Disorder or Schizophrenia 0.1 0.3 1.9 -0.4 -0.0 -1.4 0.5 -0.6 -0.1 -0.1 0.0
Depressed Affect (Nagel 2018) 0.6 1.3 2.3 -0.8 -0.3 -1.3 1.4 1.5 0.9 1.4 1.1
Depression (Nagel 2018) 1.4 2.1 3.7 0.0 -0.0 -1.6 1.9 1.4 1.6 1.9 1.6
Intelligence (Savage-Jansen 2018) 0.9 2.7 7.3 1.9 1.5 2.7 2.2 0.4 1.1 1.0 1.2
Neuroticism (Nagel 2018) 0.9 2.1 5.6 1.4 0.2 -0.9 1.2 1.8 1.1 2.4 1.7
Schizophrenia (2018) 0.2 0.4 1.3 0.9 -0.8 -1.1 -0.6 -0.4 -0.0 0.0 0.0
Schizophrenia vs Biploar Disorder 0.5 0.7 3.4 1.8 0.0 0.9 -0.9 0.3 0.6 0.0 0.0
Worry (Nagel 2018) 2.7 5.7 10.4 2.1 -1.0 -2.5 0.0 3.2 2.8 3.2 2.3
Alzheimer’s Disease (in mother) 0.6 0.7 1.4 0.4 -1.1 0.1 0.7 1.2 0.9 0.7 -1.0
Alzheimer’s Disease (in father) 0.2 0.2 0.8 0.9 -0.1 -0.1 0.6 0.0 0.2 0.6 -0.4
Alzheimer’s Disease (including proxy) 0.6 0.9 2.9 1.7 -0.7 1.0 0.2 0.7 0.7 0.9 -1.0
Crohns Disease (2017) 0.2 0.4 1.6 0.4 1.3 0.0 0.6 -0.1 0.1 0.4 1.0
Irritable Bowel Disease (IBD) 0.5 1.1 3.8 1.1 2.0 0.5 0.6 -0.6 -0.4 -0.1 1.7
Ulcerative Colitis (UC) 0.9 1.6 4.8 1.8 1.8 0.8 0.9 -0.3 0.2 0.2 2.2
Major Depression (MDD) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
Reaction Time 0.8 1.5 4.6 -2.0 0.1 0.0 0.6 -1.3 -1.1 -2.1 0.3
Verbal and Numeric Reasoning (VNR) 0.4 1.1 4.0 1.5 0.7 2.0 0.7 0.3 0.9 0.6 0.2
Breast Cancer 1.1 2.7 6.6 0.4 0.2 -0.8 2.3 1.4 1.8 2.0 2.6
Ovarian Cancer 0.5 0.7 2.0 0.1 -1.1 0.0 -1.4 0.4 -0.2 -0.1 -1.4
Prostate Cancer 0.3 0.4 2.3 -0.2 0.5 1.5 0.5 -0.2 -0.2 -0.0 0.2
Age at First Birth 0.2 0.3 0.9 0.1 0.3 1.0 -0.3 -0.4 -0.9 0.2 -0.5
Bipolar Disorder (2011) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
Body Mass Index (BMI) (2010) 0.4 0.6 2.4 -1.0 -0.6 -1.6 0.9 0.1 -0.4 0.0 0.0
Coronary Artery Disease (CAD) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
Crohns Disease (2012) 0.1 0.1 0.4 -0.4 0.2 -0.1 -0.6 -0.6 -0.4 0.0 0.0
Mean Putamen Volume 0.5 0.6 1.7 0.3 0.7 -0.3 0.4 0.4 1.0 0.8 1.3
Fasting Glucose 0.9 1.1 3.4 0.8 0.5 1.8 1.4 -1.1 -0.3 -0.9 -0.4
HbA1C 0.6 0.7 3.4 -0.6 -0.3 -0.1 -1.8 0.1 -0.5 -0.9 0.7
HDL Cholesterol 0.3 0.5 2.0 0.1 -0.7 -0.0 -0.2 1.4 1.2 0.0 0.0
LDL Cholesterol 0.7 1.2 3.4 -0.3 0.9 0.1 -1.3 -1.8 -1.9 0.0 0.0
Lupus 2.5 3.8 9.4 -0.6 2.1 1.7 0.0 -3.1 -2.8 -2.3 -0.5
Neuroticism (2016) 0.9 1.3 5.7 -2.4 -0.5 -1.3 1.2 0.8 0.1 0.5 0.7
Primary Biliary Cirrhosis 1.5 2.1 4.8 -0.5 2.1 0.6 0.4 -2.2 -1.7 -2.0 0.4
Rheumatoid Arthritis 0.5 0.7 1.6 -1.0 -0.9 -0.7 0.1 1.3 1.0 0.7 0.0
Schizophrenia (2014) 0.3 0.6 3.1 1.8 0.5 -0.6 -0.2 -0.9 -0.4 -0.5 0.0
Triglycerides 0.1 0.2 0.5 0.1 -0.5 -0.4 0.7 0.7 0.7 0.0 0.0
Type 2 Diabetes (T2D) (2012) 0.1 0.2 1.2 0.0 0.0 0.0 0.0 0.0 -1.1 0.0 0.0
Ulcerative Colitis 0.2 0.3 1.5 0.3 0.1 0.7 -0.6 0.6 1.2 0.0 0.0
Blood Eosinophil Count 0.4 3.4 8.1 -0.2 -2.1 -2.9 -2.4 2.2 0.9 1.3 -1.1
Blood Platelet Count 0.7 8.3 22.1 -1.0 -2.7 -3.1 -4.7 0.6 -1.3 -2.0 -4.5
Blood Red Count 3.1 29.9 84.8 -4.5 -6.1 -8.1 -9.2 3.8 1.0 -1.4 -3.8
Blood White Count 0.9 6.4 16.1 -0.0 -3.6 -4.0 -0.1 3.1 2.9 1.8 -0.9
Heel T-Score 5.1 40.9 118.8 -1.1 10.1 10.9 6.0 -5.8 -4.7 -3.7 0.3
BMI 1.2 7.2 24.3 -4.9 -1.2 -3.8 1.6 -0.9 -1.1 -1.5 -3.2
Height 0.4 7.7 29.6 -4.2 2.6 5.4 2.3 -0.8 -0.2 -0.5 1.0
Waist Hip Ratio (WHR) 0.5 2.4 9.3 0.6 -0.8 -3.0 -1.1 1.1 1.9 1.5 -0.3
Systolic Blood Pressure 0.4 2.2 8.9 -1.6 0.1 -2.3 -0.5 -1.0 -0.1 -3.0 -0.3
Smoking Status 0.4 0.9 5.9 -0.7 -0.3 -2.4 0.3 0.6 0.3 0.3 -0.6
Allergy or Eczema 0.3 0.9 1.6 0.5 -0.4 -1.2 -0.7 1.2 1.3 0.9 0.7
Cardiovascular Disease 0.7 2.2 10.2 -0.1 -0.3 -3.2 0.5 -0.8 0.1 -1.6 -1.9
Hypothyroidism (self reported) 0.7 1.6 6.6 2.6 0.1 -0.7 0.6 0.0 0.1 0.9 -2.1
Respiratory disease 0.6 1.3 4.0 -0.0 -1.1 -2.0 0.0 1.4 1.6 0.9 -0.1
Type 2 Diabetes (T2D) (2018) 1.2 2.2 6.2 -0.8 1.1 -1.1 -0.7 -2.1 -2.5 -1.4 -1.3
Lung FEV1/FVC ratio 0.1 0.6 1.8 0.2 0.8 -0.1 0.9 -1.3 -1.1 -0.4 -0.3
Lung FVC 0.5 2.8 6.8 1.1 -1.9 0.7 0.3 2.6 1.8 2.5 -0.7
Neuroticism 0.7 1.6 5.3 -0.1 -0.1 -2.3 1.1 1.6 0.9 1.4 1.0
Chronotype (morning person) 0.7 1.5 4.7 -0.1 -1.0 -1.1 0.4 1.8 2.2 1.3 -0.2
Hair Pigment 0.1 1.7 6.7 -2.6 -0.5 -1.9 -1.3 -0.4 -0.9 -0.5 -0.2
Tanning 0.2 2.5 7.6 -1.0 -2.8 -1.4 0.2 2.0 2.0 0.9 -0.7
Hand grip strength (left) 0.8 2.2 6.0 -0.2 -0.8 1.6 2.5 1.9 1.3 1.5 -0.8
Number of treatments/medications taken 1.2 2.2 13.9 -0.5 -1.6 -3.7 0.1 0.6 1.0 0.3 0.0
Average weekly spirits intake 0.7 0.8 2.6 -0.4 1.3 -1.6 1.3 -0.1 0.2 -0.1 0.7
Sensitivity / hurt feelings 0.3 0.5 3.1 1.8 0.0 -0.1 -0.7 0.0 -0.4 0.5 0.6
Frequency of depressed mood in last 2 weeks 1.6 2.3 5.3 0.1 -0.1 -2.3 2.0 1.7 1.3 2.0 0.6
Hearing difficulty/problems: Yes 1.7 2.6 7.7 -2.8 -0.2 -0.3 0.3 -1.4 -1.7 -1.3 -2.6
Relative age of first facial hair 1.4 2.9 7.5 -0.9 -1.9 -0.7 0.0 2.0 2.7 2.5 0.1
Other serious medical condition/disability diagnosed by doctor 0.6 0.8 2.8 -0.1 -1.7 -1.2 0.5 0.7 0.3 0.9 -0.4
Ever used hormone-replacement therapy (HRT) 1.8 2.3 5.1 -1.0 0.2 -1.8 1.6 1.3 1.5 1.7 2.2
Ever had hysterectomy (womb removed) 0.7 0.8 2.2 0.8 -0.1 -0.3 -1.0 -1.1 -1.0 -1.5 -0.3
Systolic blood pressure, automated reading 1.0 2.8 10.1 -2.1 -1.5 -3.2 -0.3 -0.5 0.2 -2.2 -0.1
Eye problems/disorders: Diabetes related eye disease 0.1 0.1 0.2 0.5 0.0 0.4 0.2 -0.4 0.3 0.4 -0.0
Angina 0.8 1.1 3.3 -1.3 -0.3 -0.8 0.6 0.8 1.4 0.1 1.8
Medication for hormone replacement therapy 0.5 0.6 1.8 0.1 -1.2 -1.3 0.4 0.9 0.6 0.2 -0.5
Vitamin and mineral supplements 0.2 0.3 0.8 0.7 -0.1 0.3 -0.9 0.2 -0.7 0.1 -0.4
Supplements: Zinc 2.1 2.2 5.4 2.3 -0.2 -0.8 0.7 1.1 1.6 1.9 2.0
Medication: Co-codamol 0.8 0.9 2.0 -1.0 0.1 -0.9 -1.1 -1.2 -1.1 -1.4 0.1
Medication: Metformin 1.0 1.4 3.9 1.2 -0.8 -2.0 0.1 1.0 0.5 1.6 -1.2
Diabetes (father) 0.7 0.9 1.8 1.1 1.3 -0.3 0.6 -1.3 -0.9 -0.6 -1.0
Diabetes (mother) 0.3 0.4 1.5 -0.1 -0.3 -1.2 -1.2 0.0 -0.0 -0.1 0.3
Severe depression (siblings) 0.5 0.5 1.7 1.3 -0.6 -0.9 -0.6 0.8 0.0 0.4 0.2
Pack years adult smoking proportion 0.3 0.5 2.0 -0.7 0.3 -1.4 0.2 0.3 0.4 0.1 1.2
Impedance of leg (right) 0.7 3.3 9.1 3.0 1.9 2.3 -2.2 -0.5 0.3 0.1 1.7
Leg fat-free mass (left) 0.9 4.7 24.5 -5.0 -0.0 -0.2 2.6 -0.9 -1.3 -0.9 -1.6
Trunk fat percentage 0.8 3.1 9.6 -3.1 -0.5 -2.8 2.2 -0.6 -0.4 -0.6 -1.1
Hand grip strength (right) 1.1 3.1 7.4 1.3 0.2 2.7 2.3 1.7 1.7 2.1 0.2
Townsend deprivation index at recruitment 1.2 1.7 4.3 -1.0 1.5 -0.5 -1.0 -1.9 -2.1 -1.3 0.1
Current tobacco smoking 1.1 1.8 5.9 0.2 -2.2 -2.4 -0.7 1.2 1.0 0.4 -0.7
Average weekly fortified wine intake 0.8 1.0 3.3 0.6 -0.4 0.1 -1.8 -0.7 -0.6 -1.8 -0.3
Maternal smoking around birth 1.6 2.3 9.7 -3.1 0.7 -1.2 -1.0 -1.1 -1.6 -1.5 0.3
Fed-up feelings 0.3 0.5 1.7 -1.3 0.8 -0.5 0.4 -0.0 -0.7 0.0 0.7
Frequency of unenthusiasm / disinterest in last 2 weeks 0.6 0.7 2.5 0.3 0.5 -1.3 0.8 0.4 0.3 1.6 0.6
Relative age voice broke 0.9 1.3 3.5 -0.3 -1.9 0.0 0.3 1.2 1.8 1.3 -0.8
Taking other prescription medications 1.4 2.1 10.4 0.0 -1.7 -3.2 0.0 1.0 0.8 0.9 -1.0
Age when periods started (menarche) 1.4 3.4 14.4 3.8 -1.0 -1.0 -2.6 1.4 1.1 1.1 0.1
Bilateral oophorectomy (both ovaries removed) 0.3 0.4 0.9 -0.0 0.5 0.8 -0.4 -0.5 -0.8 -1.0 0.3
Heel bone mineral density (BMD) T-score, automated (left) 1.9 4.3 15.2 -2.4 1.6 2.6 3.9 -1.1 -0.4 -1.3 0.6
Tinnitus: Yes, but not now, but have in the past 0.6 0.7 2.5 -1.2 -1.6 -0.7 -0.4 0.0 0.4 -0.3 -0.8
Qualifications: CSEs or equivalent 0.4 0.6 1.0 0.9 -0.8 -1.0 -0.1 0.2 -0.9 1.0 -0.6
Serious illness, injury or assault to yourself 1.2 1.4 2.9 -1.7 -1.0 -1.2 0.4 -1.1 -1.0 -1.4 -1.2
High blood pressure 0.7 2.0 10.7 0.5 -0.8 -3.3 -1.0 -0.8 0.2 -1.5 -0.7
Hayfever, allergic rhinitis or eczema 0.3 0.8 2.2 1.1 0.5 -1.5 -0.1 0.4 0.3 0.8 1.3
Multivitamins +/- minerals 0.2 0.3 0.9 -0.2 0.0 -0.5 0.7 0.2 0.9 0.3 0.9
Stomach or abdominal pain in last month 3.0 3.7 14.8 -2.0 -2.8 -3.8 -1.1 1.2 0.2 0.5 -0.0
Supplements: Glucosamine 0.8 1.1 4.6 -0.9 -0.1 -0.1 2.1 0.4 1.3 0.8 0.9
Diverticular disease/diverticulitis (self-reported) 2.0 2.4 6.8 -0.4 -2.6 -1.6 -0.9 1.6 1.9 0.8 -1.4
Medication: Atenolol 2.9 3.7 8.4 -2.0 -1.4 -2.9 -0.8 1.7 2.1 1.6 2.1
Medication: Levothyroxine sodium 0.5 0.9 4.6 2.1 -0.5 -0.6 0.6 -0.2 -0.2 0.2 -1.3
Sitting height 0.9 6.4 30.0 -3.6 2.0 5.5 0.5 -1.0 -1.1 -1.2 0.4
Chronic bronchitis/emphysema (father) 1.2 1.4 7.0 -2.6 -1.0 -1.1 -0.1 0.7 0.8 -0.5 0.9
High blood pressure (mother) 1.2 1.6 7.1 1.8 0.6 -0.2 -2.7 -1.0 -0.4 -0.8 0.7
Body mass index (BMI) 1.3 5.4 18.8 -3.6 -2.1 -4.3 1.9 -0.1 -0.4 -0.2 -1.9
Impedance of leg (left) 0.7 3.6 11.7 3.4 2.2 2.3 -1.8 -0.5 0.2 0.2 1.7
Leg predicted mass (left) 0.9 4.8 25.8 -5.1 -0.1 -0.2 2.7 -0.9 -1.2 -0.9 -1.6
Trunk fat mass 0.9 3.8 15.4 -3.9 -0.3 -2.1 2.6 -0.8 -0.7 -0.8 -1.4
Waist circumference 1.2 4.3 16.9 -2.9 -2.1 -4.1 1.1 -0.3 -0.1 -0.2 -1.8
Number of incorrect matches in round 0.8 1.4 4.8 -1.5 -1.4 -2.2 0.9 0.3 0.6 0.5 -0.6
Past tobacco smoking 0.4 0.7 2.5 1.6 0.3 1.4 -0.0 -0.5 -0.3 -0.5 -0.5
Alcohol usually taken with meals 0.3 0.5 1.3 -0.0 0.0 1.0 -0.9 -0.6 -0.1 -1.1 -0.8
Nervous feelings 0.7 1.2 2.8 0.7 0.2 -0.6 0.8 1.3 1.7 1.1 1.7
Frequency of tenseness / restlessness in last 2 weeks 2.6 4.0 15.6 0.6 -1.1 -4.0 0.6 2.0 1.8 2.4 1.2
Hearing difficulty/problems with background noise 0.3 0.5 1.2 -1.0 -0.1 -0.9 -0.4 -0.4 -0.6 -0.2 -1.1
Hair/balding pattern: Pattern 2 0.4 0.5 0.9 -0.7 -0.6 -1.0 -0.4 0.9 0.1 0.8 0.6
Had menopause 0.4 0.5 1.2 -0.7 -0.9 -0.3 0.8 0.5 1.1 0.5 0.3
Had other major operations 0.2 0.3 1.0 -0.7 -0.1 0.6 0.4 -0.0 0.4 -0.2 1.0
Forced vital capacity (FVC) 0.5 1.9 7.9 -1.8 1.2 2.8 0.7 0.9 0.5 0.9 0.9
Heel bone mineral density (BMD) T-score, automated (right) 1.7 3.9 14.0 -1.6 1.8 2.9 3.7 -1.3 -0.5 -0.9 0.5
Ever unenthusiastic/disinterested for a whole week 1.6 1.9 5.2 0.2 0.5 -2.3 2.0 1.0 0.1 2.1 0.7
Qualifications: None of the above 0.7 1.5 4.7 -2.2 -0.7 -2.0 -1.5 -0.1 -0.0 -0.3 -0.0
Financial difficulties in last 2 years 1.2 1.7 9.5 -0.5 -1.2 -3.1 0.7 0.3 -0.1 1.0 -0.8
Mouth/teeth dental problems 1.2 1.8 3.6 0.5 1.4 1.9 0.6 -1.7 -1.6 -0.6 -1.5
Heart attack 0.4 0.5 1.5 -1.2 -0.4 -1.2 0.2 0.0 -0.3 -0.6 -0.7
Allergy 0.3 0.7 2.8 -0.5 0.1 1.7 0.2 -0.4 -0.7 -0.6 -1.1
Pain all over the body in last month 0.4 0.4 1.7 0.1 0.1 -1.3 -1.1 -0.4 -0.5 -0.1 -0.5
Diabetes (self-reported) 0.7 1.0 2.1 -0.4 0.5 -1.1 -0.7 -1.3 -1.5 -1.1 -1.1
Hayfever/allergic rhinitis (self-reported) 0.3 0.4 1.3 0.5 1.1 -0.7 0.5 0.2 -0.0 0.5 0.9
Medication: Ramipril 0.6 0.8 2.5 1.0 -1.5 -0.2 0.3 0.4 0.3 -0.6 -1.6
Medication: Simvastatin 0.9 1.4 5.5 -2.3 -0.4 -1.5 1.4 -0.1 0.5 -0.2 1.0
Fluid intelligence score 0.5 1.1 4.2 1.1 0.4 2.1 1.3 0.2 0.8 0.8 0.2
Illnesses of siblings 1.4 1.9 7.9 1.6 -0.6 2.8 0.8 1.4 0.7 1.2 -0.5
Neuroticism score 0.7 1.4 2.6 0.2 0.2 -1.4 1.4 1.6 1.1 1.5 1.2
Weight 0.9 4.6 23.6 -4.9 -0.5 -1.4 2.4 -0.9 -1.1 -1.0 -1.5
Impedance of arm (right) 0.3 1.2 3.0 1.2 1.1 1.7 -1.5 0.2 0.6 -0.2 1.0
Arm fat percentage (right) 1.2 4.8 16.9 -3.5 -1.7 -4.1 1.7 -0.1 -0.1 -0.4 -1.6
Trunk fat-free mass 0.5 2.8 16.1 -4.0 -0.1 1.2 1.5 -0.6 -1.0 -0.4 -1.0
Hip circumference 1.0 4.1 18.2 -4.3 -0.7 -2.1 1.9 -1.0 -1.4 -1.3 -1.3
Time employed in main current job 1.1 1.3 3.7 -1.0 -0.4 -1.9 1.0 0.6 1.5 0.1 1.2
Alcohol intake versus 10 years previously 1.3 1.9 4.3 0.1 1.2 1.1 -0.9 -1.7 -2.1 -2.0 -0.8
Father’s age at death 1.0 1.4 4.9 0.8 1.3 2.2 0.6 -1.0 -1.1 -0.9 0.5
Worrier / anxious feelings 0.6 1.2 2.6 1.6 0.1 -0.0 0.1 1.4 1.1 1.4 1.3
Frequency of tiredness / lethargy in last 2 weeks 0.7 1.1 5.4 0.9 0.5 -2.3 0.2 -0.9 -0.8 -0.3 -0.7
Falls in the last year 2.5 3.3 13.1 -2.1 -2.4 -3.6 0.3 1.2 1.0 0.7 -0.3
Hair/balding pattern: Pattern 3 0.4 0.6 1.3 0.9 -0.3 -0.2 -0.4 1.0 1.2 1.0 -0.4
Number of live births 0.9 1.2 4.9 -1.1 -1.2 -2.2 -0.4 0.3 0.1 -1.3 -0.4
Forced expiratory volume in 1-second (FEV1) 0.5 1.7 7.3 -1.5 1.5 2.7 0.8 -0.3 -0.8 -0.1 0.1
Pulse rate 1.2 2.1 4.0 -0.1 -1.6 -1.2 1.3 1.8 2.0 1.8 0.1
Happiness 0.5 0.6 1.9 0.6 1.2 0.0 -0.2 -0.9 -1.4 -0.7 0.2
Noisy workplace 0.9 1.1 7.7 -0.4 0.3 -2.8 0.9 -0.3 -0.3 0.3 0.3
Qualifications: A levels/AS levels or equivalent 0.5 1.2 2.7 1.6 1.6 1.5 -0.4 -0.5 -0.4 0.3 1.0
Serious illness, injury or assault of a close relative in last 2 years 0.2 0.3 0.9 0.7 0.4 1.0 0.2 0.3 0.4 -0.3 0.5
Mouth/teeth dental problems: Dentures 1.3 2.2 6.7 -1.4 -2.6 -2.3 -1.1 0.9 0.7 -0.1 -0.9
Asthma 0.4 0.7 2.3 -0.3 0.1 -1.0 -0.3 0.8 1.2 0.5 1.5
Medication: Ibuprofen (e.g. Nurofen) 1.5 1.9 3.9 -1.3 0.5 -2.0 0.6 -1.9 -1.3 -1.5 -1.5
Medication: Cholesterol lowering 0.5 0.8 4.5 -0.1 -0.4 -2.1 0.5 0.3 0.7 0.3 1.0
Depression (self-reported) 0.4 0.5 1.0 1.0 1.0 -0.3 0.7 0.6 0.1 1.0 0.1
Medication: Lansoprazole 1.8 2.0 6.1 -0.4 -1.6 -2.5 -0.4 1.8 1.2 1.0 1.4
Prospective memory result 0.6 0.7 4.5 2.1 0.3 -0.1 -0.9 0.1 -0.4 0.4 -0.0
Lung cancer (father) 1.0 1.1 3.4 -0.9 -1.8 -1.1 -1.8 0.3 0.1 0.3 -0.5
Illnesses of mother 0.8 1.0 2.4 -1.6 0.1 -0.4 1.5 0.9 0.4 1.0 -0.9
Forced expiratory volume in 1-second (FEV1), Best measure 0.6 1.9 6.7 -2.6 1.2 2.2 0.6 -0.3 -1.0 0.0 -0.8
Pulse wave Arterial Stiffness index 0.3 0.3 0.9 -0.7 0.5 -0.3 -0.9 -0.4 -0.1 -0.2 0.9
Impedance of arm (left) 0.2 1.1 2.2 1.0 1.5 1.1 -1.1 0.2 0.7 -0.3 1.4
Arm fat mass (right) 1.1 4.4 16.6 -4.1 -1.2 -3.1 2.0 -0.5 -0.7 -0.5 -1.6
Trunk predicted mass 0.5 2.7 16.0 -4.0 -0.2 1.0 1.5 -0.5 -1.0 -0.4 -0.9
Standing height 0.8 7.8 34.6 -3.5 2.9 5.9 1.2 -1.5 -1.2 -1.4 0.5
Length of working week for main job 2.0 2.2 4.7 -1.6 1.6 -0.9 2.2 -1.9 -1.8 -0.6 0.3
Exposure to tobacco smoke at home 0.5 0.5 1.6 0.7 -1.3 -0.2 0.8 0.1 0.1 0.4 -1.0
Breastfed as a baby 1.7 2.1 9.1 1.6 -0.8 0.2 -3.0 -0.9 -0.7 -1.5 -1.2
Tense / ‘highly strung’ 2.0 3.3 7.6 1.5 -0.2 -1.8 0.9 2.4 1.9 2.8 1.9
Seen doctor (GP) for nerves, anxiety, tension or depression 1.6 2.4 5.1 1.7 0.4 -1.8 0.8 1.6 1.1 2.3 1.8
Hair/balding pattern: Pattern 4 0.8 1.9 8.1 2.8 1.5 0.4 0.9 -1.1 -0.8 -1.5 -0.3
Birth weight of first child 0.5 1.0 2.2 0.4 -1.2 1.2 -0.8 1.5 1.2 0.6 -0.3
Peak expiratory flow (PEF) 0.9 2.0 4.4 -2.0 1.6 2.1 0.1 -1.3 -1.2 -1.2 -0.4
Pulse wave reflection index 0.3 0.3 1.2 0.1 0.6 0.5 -0.5 -1.1 -0.6 -0.5 0.3
Ever highly irritable/argumentative for 2 days 1.4 1.7 10.9 0.5 -0.9 -3.3 0.2 0.4 -0.0 1.1 -0.5
Loud music exposure frequency 1.7 1.8 3.8 0.6 1.4 1.7 0.0 -1.5 -1.9 -1.2 -1.4
Qualifications: O levels/GCSEs or equivalent 0.7 1.1 2.4 1.4 0.3 1.6 0.6 1.1 1.3 0.7 1.1
Mouth/teeth dental problems: Bleeding gums 1.7 2.2 9.7 -0.6 1.1 0.4 1.4 0.9 1.2 1.3 3.1
Blood clot in the leg (DVT) 1.0 1.2 5.7 1.1 -0.1 -0.6 -0.2 1.0 1.1 0.8 2.4
Medication: Paracetamol 0.6 1.0 5.1 -1.1 -0.8 -2.2 -0.6 -0.1 -0.2 -0.6 0.2
Headache pain in last month 0.3 0.5 1.5 -0.7 -0.7 -1.2 -0.1 0.9 0.4 0.5 0.5
Medication for cholesterol, blood pressure or diabetes 0.3 0.5 2.7 0.1 -0.1 1.6 0.5 0.5 0.0 0.4 -0.6
Glaucoma (self-reported) 0.1 0.1 0.5 0.7 -0.2 -0.1 -0.0 0.1 0.1 0.3 -0.0
Gout (self-reported) 0.9 1.2 3.6 -0.0 0.1 1.9 1.8 0.4 1.3 0.7 0.2
Hypothyroidism/myxoedema (self-reported) 0.6 1.2 6.1 2.5 -0.1 -0.0 0.8 -0.4 -0.1 0.4 -1.6
Medication: Amlodipine 0.2 0.3 1.0 -0.6 -0.4 -1.0 -0.1 -0.4 0.0 -0.7 -0.2
Medication: Ventolin 100micrograms inhaler 1.0 1.2 2.8 -0.6 -0.6 -0.4 -0.0 1.5 1.7 1.1 1.7
Birth weight 1.3 2.8 12.6 0.9 2.1 3.5 -0.9 -0.6 -0.1 0.3 1.8
Chronic bronchitis/emphysema (mother) 0.1 0.1 0.6 0.2 -0.3 -0.8 0.1 0.2 0.2 0.4 -0.2
High blood pressure (siblings) 0.7 1.0 5.1 -0.6 0.6 -2.3 -0.3 -0.5 0.1 -0.1 1.2
Forced vital capacity (FVC), Best measure 0.6 2.3 7.8 -2.8 1.1 2.7 0.3 0.9 0.1 1.1 0.1
Body fat percentage 0.8 3.3 10.3 -3.0 -0.8 -3.2 2.0 -0.7 -0.4 -0.6 -1.4
Leg fat percentage (right) 0.9 3.1 12.5 -2.4 -1.3 -3.5 0.9 -0.9 -0.7 -0.8 -1.6
Arm fat-free mass (right) 0.6 3.3 16.8 -4.1 0.1 0.4 2.1 -1.0 -1.4 -0.7 -1.1
Exposure to tobacco smoke outside home 0.9 1.3 3.9 0.5 0.0 -0.5 -1.1 -1.5 -2.0 -1.2 -0.7
Comparative body size at age 10 0.3 1.0 3.3 -0.6 -0.5 -1.4 1.8 0.2 0.3 0.9 -0.9
Number of full brothers 3.9 4.9 20.4 -1.8 -2.9 -4.5 -1.0 0.8 0.4 0.6 -2.2
Worry too long after embarrassment 0.7 1.1 2.8 -0.0 1.7 0.8 1.4 -1.3 -1.3 -0.1 -0.6
Seen a psychiatrist for nerves, anxiety, tension or depression 1.0 1.3 2.8 -0.2 1.3 -1.6 1.7 0.0 -0.3 1.5 1.1
Wheeze or whistling in the chest in last year 1.0 1.8 7.9 -0.6 0.9 -2.8 1.8 -0.0 0.2 0.6 1.4
Number of children fathered 0.3 0.4 0.9 -0.9 -0.6 -0.1 -0.9 -0.5 -0.1 -0.6 -0.3
Reason for reducing amount of alcohol drunk: Health precaution 2.4 2.8 5.5 -1.2 -1.3 -1.8 1.1 1.8 2.3 1.9 1.6
Age at first live birth 0.8 1.3 3.7 1.9 -0.6 0.4 1.4 1.1 1.1 1.1 -0.8
Pulse wave peak to peak time 0.2 0.3 1.0 0.5 -0.3 0.5 0.8 0.2 -0.1 -0.1 -1.0
Health satisfaction 1.8 2.3 5.4 0.1 -2.3 -2.1 0.0 1.9 1.4 1.7 -0.0
Shortness of breath walking on level ground 0.5 0.6 1.3 -1.1 -1.1 -0.9 -0.6 0.4 0.6 0.7 -0.4
Qualifications: College or University degree 0.4 1.3 4.3 -0.4 1.8 2.1 1.3 -0.5 -0.2 -0.1 1.0
Eye problems/disorders: None of the above 0.6 0.7 2.9 -0.2 -0.5 -1.7 1.1 0.6 0.5 0.7 0.1
Mouth/teeth dental problems: Loose teeth 1.2 1.4 5.4 0.0 1.1 -1.7 0.1 0.2 0.3 1.2 2.3
Emphysema/chronic bronchitis 0.1 0.1 0.3 0.2 0.1 0.1 0.3 -0.6 -0.2 0.0 0.1
Medication for pain relief, constipation, heartburn 1.6 2.7 18.3 1.1 1.3 4.3 -0.5 -0.3 -0.4 -0.4 0.3
Neck or shoulder pain in last month 0.6 0.8 2.1 -1.3 -0.8 -1.5 0.0 0.6 0.4 0.1 1.4
Medication: Blood pressure 0.4 0.7 1.6 -0.5 0.9 -0.8 -0.9 -1.2 -0.6 -0.8 0.7
Angina (self-reported) 1.1 1.4 4.2 -1.1 -0.1 -1.0 0.8 1.0 1.6 0.5 2.0
Migraine (self-reported) 0.3 0.4 0.9 -0.8 0.3 0.1 -0.1 -0.6 -0.8 -0.9 1.0
Medication: Ibuprofen 1.6 1.9 4.2 -0.8 0.4 -2.1 0.0 -1.9 -1.4 -1.7 -1.4
Medication: Allopurinol 0.7 1.0 3.8 0.1 1.0 1.9 1.2 -0.0 0.7 0.2 0.9
Medication: Omeprazole 2.6 3.1 9.0 -0.6 -2.9 -3.0 0.4 1.5 1.2 1.2 -1.4
Medication: Seretide 50 evohaler 1.3 1.5 4.2 -0.1 -1.0 -2.0 0.2 1.6 1.4 1.1 0.9
Mean time to correctly identify matches 0.7 1.3 4.8 -2.0 -0.4 -0.1 0.2 -1.1 -0.7 -2.2 0.1
Heart disease (mother) 0.5 0.6 2.7 0.3 0.8 0.3 0.5 -0.7 -0.1 -0.7 1.7
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.7 0.9 5.4 0.8 0.8 -0.1 2.3 -0.4 0.0 0.4 0.4
Whole body fat mass 0.9 3.9 15.6 -4.0 -0.8 -2.6 2.1 -0.7 -0.7 -0.7 -1.6
Leg fat mass (right) 1.0 3.9 14.7 -3.8 -0.8 -2.6 1.7 -1.2 -1.1 -0.9 -1.6
Arm predicted mass (right) 0.7 3.4 16.9 -4.1 0.2 0.6 2.3 -1.0 -1.3 -0.6 -1.1
Pulse rate, automated reading 0.9 3.0 4.6 0.1 -2.1 -1.7 2.0 1.9 2.0 1.7 -1.4
Alcohol intake frequency. 0.6 1.5 3.1 1.2 1.8 1.5 0.2 -1.2 -1.1 -0.6 1.3
Comparative height size at age 10 0.8 4.3 10.2 -3.2 1.8 3.0 0.8 -1.8 -1.4 -2.4 -0.7
Number of full sisters 0.4 0.5 1.1 0.1 0.4 0.4 -0.9 -1.0 -0.8 -1.0 0.6
Suffer from ‘nerves’ 1.7 2.6 6.0 1.0 -0.7 -0.9 0.3 2.2 2.3 2.4 1.6
Overall health rating 0.8 1.7 12.0 -0.1 -1.1 -3.5 0.3 0.2 0.1 0.7 -0.3
Chest pain or discomfort 0.8 1.2 5.4 -2.3 0.1 -1.4 1.2 -0.4 -0.5 -0.4 0.4
Had major operations 0.4 0.4 1.2 0.4 -0.7 -1.1 0.8 0.5 -0.1 0.4 -0.8
Age at last live birth 0.5 0.7 2.5 1.2 -0.4 -1.6 1.0 0.6 0.4 0.3 0.3
Family relationship satisfaction 0.3 0.4 1.7 1.3 0.8 0.5 -0.2 -0.3 -0.4 0.3 0.2
Leg pain on walking 1.0 1.2 3.8 -0.7 1.1 -2.0 -0.5 -0.8 -1.0 0.5 1.5
Qualifications: NVQ or HND or HNC or equivalent 0.2 0.3 1.5 1.2 0.3 -0.0 -0.5 -0.1 0.1 0.2 0.1
Commuting to job workplace: Car/motor vehicle 0.7 0.9 3.5 -1.0 0.1 -0.7 1.9 -0.2 0.9 -0.1 1.0
Illness, injury, bereavement, stress in last 2 years 0.1 0.2 0.7 -0.0 0.3 0.6 -0.8 -0.1 -0.2 0.1 0.2
Medication: Aspirin 0.7 0.9 3.0 -0.3 -0.8 -1.7 -0.2 0.9 1.3 0.7 0.4
Supplements: Vitamin C 0.8 1.0 4.1 0.7 -0.5 -2.0 0.3 0.2 0.8 1.1 1.1
Knee pain experienced in last month 0.6 0.9 3.3 -0.7 0.6 -1.8 -0.1 -0.6 -0.6 -0.3 1.5
Hypertension (Self-reported) 0.5 1.5 8.4 0.6 -0.8 -2.9 -0.9 -0.5 0.6 -0.9 -0.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 4.5 5.3 13.7 -1.8 -3.7 -3.3 0.4 2.6 2.1 0.6 -1.6
Illnesses of father: Heart disease 0.3 0.4 1.0 0.5 -0.3 -0.8 0.8 1.0 0.4 0.5 -0.6
Illnesses of siblings: Diabetes 0.7 0.8 3.2 -1.8 0.2 -1.7 -0.3 -0.4 -0.1 -0.2 0.4
Smoking status: Previous 0.2 0.3 1.3 -1.1 0.3 -0.6 0.3 0.1 -0.1 0.3 0.5
Forced expiratory volume in 1-second (FEV1), predicted 1.0 2.1 4.9 -1.6 1.8 2.2 1.2 -1.0 -1.2 -1.3 0.7
Whole body fat-free mass 0.6 3.6 19.9 -4.5 -0.1 0.6 2.0 -0.8 -1.2 -0.6 -1.3
Leg fat-free mass (right) 0.8 4.4 22.3 -4.7 0.0 -0.2 2.8 -0.8 -1.3 -0.7 -1.6
Arm fat percentage (left) 1.3 5.3 19.3 -3.7 -1.5 -4.4 2.1 -0.1 -0.0 -0.5 -1.4
Average weekly red wine intake 0.8 1.2 3.0 -0.8 -1.7 -0.6 -1.2 0.4 0.8 -0.8 -1.5
Handedness (chirality/laterality): Left-handed 0.2 0.3 1.0 -0.7 -0.2 1.0 -0.5 0.1 -0.2 -0.1 -0.6
Mood swings 0.2 0.4 1.2 -0.7 -0.5 -0.8 -0.4 0.2 -1.1 -0.3 -0.2
Loneliness, isolation 1.7 2.4 5.4 0.1 -0.7 -0.9 2.3 1.8 1.8 2.2 1.0
Long-standing illness, disability or infirmity 0.7 1.0 2.5 0.4 -1.3 -1.6 0.2 1.3 0.9 1.0 0.4
Ever had bowel cancer screening 2.0 2.3 5.5 -1.0 -0.3 -0.8 1.0 1.7 2.2 1.5 2.3
Diabetes diagnosed by doctor 0.8 1.3 2.9 -0.1 0.4 -1.4 -0.8 -1.7 -1.6 -1.1 -1.1
Ever had stillbirth, spontaneous miscarriage or termination 1.1 1.2 6.5 0.2 0.0 -2.5 1.3 0.4 0.7 0.5 0.5
Friendships satisfaction 0.4 0.4 1.0 1.0 -0.1 0.0 -0.7 -0.2 -0.9 1.0 -0.3
Qualifications: nursing, teaching 0.5 0.7 1.7 0.1 -0.7 0.5 1.1 1.0 1.3 1.2 -0.2
Commuting to job workplace: Walk 0.6 0.6 1.3 -0.3 0.9 1.1 0.9 -0.4 -1.0 -0.3 -0.8
Eye problems/disorders: Cataract 1.9 2.2 6.5 -0.4 1.9 2.5 -1.3 -1.5 -1.2 -1.3 0.8
Mouth/teeth dental problems: Mouth ulcers 0.5 0.8 1.8 0.2 -0.9 -1.2 -0.3 1.3 1.1 0.6 0.9
Medication for cholesterol 0.9 1.4 2.7 -0.7 1.6 1.4 1.6 -0.1 0.3 1.2 1.4
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.9 1.1 6.2 0.0 0.4 0.9 2.5 -0.5 -0.3 1.0 0.3
Back pain experienced in last month 0.7 1.1 3.9 -0.9 -1.4 -2.0 -0.8 0.6 0.6 -0.0 0.3
Mineral and other dietary supplements 0.4 0.6 3.2 0.8 0.0 0.4 -0.2 0.2 -0.8 0.2 -1.8
Breast cancer (self-reported) 0.8 0.9 2.4 -1.0 0.5 1.2 1.1 -1.0 -0.2 -1.6 -0.5
Asthma (self-reported) 0.4 0.7 2.5 0.1 0.3 -1.0 -0.5 0.7 1.1 0.6 1.6
Osteoporosis (self-reported) 3.5 4.3 8.6 2.0 -2.8 -2.3 -0.9 2.3 2.9 1.7 0.2
Osteoarthritis (self-reported) 0.4 0.5 1.5 0.6 -0.6 -0.5 0.7 0.5 1.2 0.7 0.4
Medication: Aspirin 0.8 1.0 2.6 -0.1 -0.5 -1.6 0.6 1.1 1.6 0.9 0.8
Medication: Gliclazide 1.0 1.1 2.5 0.4 0.3 -1.5 -0.9 -0.9 -1.6 0.0 -1.5
Illnesses of father: None of the above (group 1) 0.7 0.8 2.0 -0.2 -1.0 1.4 -1.4 1.0 0.7 0.3 -0.0
Smoking status: Current 0.6 1.0 3.7 0.0 -1.5 -1.9 -0.7 0.9 0.7 0.2 -0.1
Forced expiratory volume in 1-second (FEV1), predicted percentage 1.4 3.0 7.9 -1.4 -1.5 0.3 0.8 2.8 2.5 2.2 -0.4
Whole body water mass 0.6 3.7 20.9 -4.6 -0.0 0.6 2.0 -0.8 -1.3 -0.6 -1.2
Leg predicted mass (right) 0.8 4.4 22.3 -4.7 0.1 -0.1 2.7 -0.8 -1.3 -0.8 -1.6
Arm fat mass (left) 1.1 4.6 16.1 -4.0 -1.2 -3.4 2.3 -0.2 -0.5 -0.3 -1.5
Number of self-reported non-cancer illnesses 2.0 3.5 11.0 -0.4 -1.1 -3.3 1.5 1.9 2.5 1.2 1.5
Average weekly champagne plus white wine intake 0.9 1.2 3.4 -0.6 1.9 0.5 0.5 -1.4 -1.7 -0.8 0.3
Miserableness 0.4 0.7 1.5 -1.0 0.8 -0.8 1.2 -0.4 -1.0 -0.5 -0.6
Guilty feelings 0.9 1.3 4.1 1.1 1.5 -0.8 0.3 0.5 -0.1 1.4 2.0
Wears glasses or contact lenses 0.9 1.0 2.3 -0.2 -1.1 -1.4 -0.4 1.5 1.3 0.8 0.6
Ever taken oral contraceptive pill 1.4 1.6 4.9 1.7 1.3 2.2 0.7 -0.2 -0.2 0.8 1.4
Hearing aid user 0.6 0.7 5.3 -2.3 -0.1 -0.2 -0.4 -0.1 0.2 0.1 0.2
Mother’s age at death 1.2 1.5 4.8 1.4 1.5 2.2 -1.1 -0.8 -0.1 -0.4 1.1
Financial situation satisfaction 1.0 1.2 3.6 1.9 1.0 -0.1 -0.6 -1.1 -1.8 -0.2 0.3
Tinnitus: Yes, now most or all of the time 0.6 0.7 2.5 0.7 -1.1 -1.6 -1.0 0.3 -0.2 0.0 -0.7
Commuting to job workplace: Public transport 2.1 2.5 5.6 2.1 1.0 2.4 -2.0 -1.3 -1.4 -1.0 -0.8
Eye problems/disorders: Glaucoma 0.1 0.1 0.5 0.6 0.1 0.7 0.1 0.2 0.0 0.3 -0.0
Medication: Blood pressure 0.5 0.9 2.8 0.1 -0.6 -0.9 -0.5 -0.8 -0.5 -1.7 -1.5
Pain type(s) experienced in last month: Hip pain 1.4 1.7 6.8 -2.0 0.8 -2.6 0.5 -0.8 -0.2 -0.1 1.1
Supplements: Fish oil (including cod liver oil) 0.4 0.5 2.0 -0.9 -0.0 -0.4 -0.7 -0.3 0.3 -0.4 1.4
High cholesterol (Self-reported) 1.1 1.9 5.9 0.0 -1.4 -2.4 1.8 1.1 1.7 0.4 0.3
Medication: Bendroflumethiazide 0.6 1.0 2.6 0.7 -1.5 -0.8 -0.2 0.7 1.0 -0.4 -1.6
Medication: Paracetamol 0.5 0.8 2.8 -0.8 -0.7 -1.7 -0.9 -0.2 -0.6 -1.2 -0.0
Medication: Lisinopril 1.1 1.4 4.5 -0.6 0.0 -0.3 -1.3 -1.2 -1.4 -2.1 -1.0
Medication: Atorvastatin 0.3 0.4 1.5 0.7 0.6 -0.3 1.2 -0.6 -0.2 0.1 -0.8
Illnesses of father: High blood pressure 1.3 1.6 3.5 1.0 1.2 -1.1 0.5 -1.9 -1.6 -1.5 -0.0
Alcohol drinker status: Never 0.1 0.1 0.3 -0.2 -0.1 0.2 0.6 0.2 -0.1 0.4 0.1
Ever smoked 0.4 0.7 1.5 -1.2 -0.7 -1.0 -0.2 1.0 0.7 0.8 0.4
Basal metabolic rate 0.7 3.9 21.4 -4.6 -0.1 0.1 2.2 -0.8 -1.3 -0.7 -1.4
Leg fat percentage (left) 0.8 3.0 12.2 -2.1 -1.1 -3.5 1.2 -0.9 -0.7 -0.8 -1.6
Arm fat-free mass (left) 0.6 2.8 14.0 -3.7 -0.1 0.3 1.9 -0.9 -1.5 -0.5 -1.3
Number of operations (self-reported) 0.3 0.5 1.4 0.5 -0.3 -1.2 -0.6 -0.1 -0.8 -0.9 -0.5
Average weekly beer plus cider intake 1.1 1.7 3.3 -1.2 -0.8 -1.8 0.2 1.7 1.5 1.4 0.8
Irritability 1.1 1.8 5.8 0.1 1.5 0.8 2.4 0.9 0.3 1.8 1.2
Risk taking 0.6 0.9 3.3 -1.2 -1.2 -1.8 -0.5 0.1 -0.4 -0.4 -0.5
Ever had prostate specific antigen (PSA) test 0.9 1.0 4.8 -0.5 0.6 -0.4 -0.6 -0.7 -0.2 -1.4 2.2
Fractured/broken bones in last 5 years 1.0 1.4 4.5 1.0 -0.8 -2.1 0.1 0.9 0.8 1.6 0.9
Age started oral contraceptive pill 0.4 0.5 1.3 -0.9 0.3 1.1 1.1 -0.6 -0.1 -0.3 -0.0
Diastolic blood pressure, automated reading 0.5 1.6 6.8 -0.3 -1.4 -2.6 -0.5 -0.5 -0.2 -1.6 -1.1
Ever depressed for a whole week 1.4 1.7 7.1 -0.4 -0.1 -2.0 2.7 0.5 0.1 1.5 -0.2
Unable to work because of sickness or disability 0.7 1.0 4.3 -0.3 -1.5 -2.1 0.0 -0.2 -0.2 -0.5 -0.9
Commuting to job workplace: Cycle 0.5 0.6 1.8 -0.6 0.0 1.2 1.3 0.1 0.6 -0.9 0.0
Myopia 1.3 1.9 5.5 0.6 2.4 1.6 0.1 -1.5 -1.2 -1.6 -0.4
Vascular/heart problems diagnosed by doctor 0.9 2.6 14.4 -0.6 1.6 3.8 1.0 0.2 -0.7 1.3 0.5
Cholesterol lowering medication 0.6 0.9 3.4 -1.4 -1.1 -1.9 -0.2 0.3 0.2 -0.1 -0.1
Medication: Omeprazole (e.g. Zanprol) 4.7 5.7 15.1 -0.4 -3.8 -3.9 0.5 2.4 2.2 1.9 -1.3
Pain experienced in last month 1.1 1.9 9.1 1.2 -0.3 3.0 -0.0 -0.3 0.1 -0.3 -2.0
Supplements: Calcium 0.7 0.8 1.8 0.9 0.5 1.0 -1.1 0.2 0.9 0.5 1.3
Basal cell carcinoma (self-reported) 0.3 0.4 2.3 -1.5 0.4 0.2 -0.6 0.2 0.2 -0.0 0.2
Heart attack/myocardial infarction (self-reported) 0.6 0.7 2.4 -1.5 -0.7 -1.5 0.2 0.0 -0.2 -0.5 -0.6
Deep venous thrombosis (DVT) (self-reported) 1.2 1.6 6.4 1.1 -0.3 -0.9 -0.1 1.2 1.4 0.8 2.5
Heart disease (siblings) 1.1 1.4 8.5 1.0 0.0 -2.9 1.0 -0.0 0.6 0.3 0.5
Alcohol drinker status: Previous 1.0 1.1 3.1 -1.0 -0.6 0.3 0.6 1.2 1.3 1.0 1.8
Pack years of smoking 0.5 0.8 2.8 -0.5 0.1 -1.5 0.1 0.5 0.7 0.3 1.7
Impedance of whole body 0.5 2.7 6.6 2.6 2.1 2.3 -1.3 -0.2 0.5 -0.2 1.7
Leg fat mass (left) 0.9 3.7 13.0 -3.6 -0.6 -2.6 2.1 -1.1 -1.0 -0.7 -1.5
Arm predicted mass (left) 0.6 3.0 15.8 -4.0 -0.2 0.6 1.4 -1.1 -1.6 -0.7 -1.3