Hub : Genes

POLR3K

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adrenal Gland	0.1274	0.0675	9.1e-03	-0.003	NA	-0.008	NA	-0.005	4.1e-01	NA	8.6e-01	NA	5.6e-01
2	GTEx	Artery Tibial	0.1210	0.0576	7.8e-03	0.002	NA	-0.001	NA	0.004	2.1e-01	NA	3.8e-01	NA	1.3e-01
3	GTEx	Brain Cerebellar Hemisphere	0.3320	0.1000	3.0e-04	0.010	NA	0.036	NA	0.042	1.7e-01	NA	4.3e-02	NA	3.1e-02
4	METSIM	Adipose	0.0899	0.0354	2.0e-04	0.012	0.024	0.026	0.026	0.023	4.7e-03	1.3e-04	6.8e-05	6.7e-05	1.7e-04
5	NTR	Blood	0.0351	0.0108	2.5e-07	0.026	0.027	0.037	0.030	0.035	5.5e-09	4.2e-09	6.5e-12	4.9e-10	1.8e-11
6	YFS	Blood	0.1769	0.0308	0.0e+00	0.151	0.155	0.153	0.158	0.161	5.3e-47	3.0e-48	1.2e-47	2.6e-49	3.0e-50
7	TCGA	Soft Tissue Sarcoma	0.0880	0.0520	4.6e-03	-0.001	0.028	0.002	NA	0.010	3.5e-01	8.7e-03	2.2e-01	NA	7.5e-02
8	TCGA	Stomach Adenocarcinoma	0.1020	0.0390	1.3e-04	0.081	0.063	0.057	NA	0.067	1.9e-06	2.5e-05	5.8e-05	NA	1.4e-05

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8
Bipolar Disorder (2018)	0.6	0.9	3.0	-1.7	1.0	-0.8	1.6	-0.5	-0.1	-0.1	0.0
Bipolar Disorder or Schizophrenia	0.1	0.3	1.9	-0.4	-0.0	-1.4	0.5	-0.6	-0.1	-0.1	0.0
Depressed Affect (Nagel 2018)	0.6	1.3	2.3	-0.8	-0.3	-1.3	1.4	1.5	0.9	1.4	1.1
Depression (Nagel 2018)	1.4	2.1	3.7	0.0	-0.0	-1.6	1.9	1.4	1.6	1.9	1.6
Intelligence (Savage-Jansen 2018)	0.9	2.7	7.3	1.9	1.5	2.7	2.2	0.4	1.1	1.0	1.2
Neuroticism (Nagel 2018)	0.9	2.1	5.6	1.4	0.2	-0.9	1.2	1.8	1.1	2.4	1.7
Schizophrenia (2018)	0.2	0.4	1.3	0.9	-0.8	-1.1	-0.6	-0.4	-0.0	0.0	0.0
Schizophrenia vs Biploar Disorder	0.5	0.7	3.4	1.8	0.0	0.9	-0.9	0.3	0.6	0.0	0.0
Worry (Nagel 2018)	2.7	5.7	10.4	2.1	-1.0	-2.5	0.0	3.2	2.8	3.2	2.3
Alzheimer’s Disease (in mother)	0.6	0.7	1.4	0.4	-1.1	0.1	0.7	1.2	0.9	0.7	-1.0
Alzheimer’s Disease (in father)	0.2	0.2	0.8	0.9	-0.1	-0.1	0.6	0.0	0.2	0.6	-0.4
Alzheimer’s Disease (including proxy)	0.6	0.9	2.9	1.7	-0.7	1.0	0.2	0.7	0.7	0.9	-1.0
Crohns Disease (2017)	0.2	0.4	1.6	0.4	1.3	0.0	0.6	-0.1	0.1	0.4	1.0
Irritable Bowel Disease (IBD)	0.5	1.1	3.8	1.1	2.0	0.5	0.6	-0.6	-0.4	-0.1	1.7
Ulcerative Colitis (UC)	0.9	1.6	4.8	1.8	1.8	0.8	0.9	-0.3	0.2	0.2	2.2
Major Depression (MDD)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Reaction Time	0.8	1.5	4.6	-2.0	0.1	0.0	0.6	-1.3	-1.1	-2.1	0.3
Verbal and Numeric Reasoning (VNR)	0.4	1.1	4.0	1.5	0.7	2.0	0.7	0.3	0.9	0.6	0.2
Breast Cancer	1.1	2.7	6.6	0.4	0.2	-0.8	2.3	1.4	1.8	2.0	2.6
Ovarian Cancer	0.5	0.7	2.0	0.1	-1.1	0.0	-1.4	0.4	-0.2	-0.1	-1.4
Prostate Cancer	0.3	0.4	2.3	-0.2	0.5	1.5	0.5	-0.2	-0.2	-0.0	0.2
Age at First Birth	0.2	0.3	0.9	0.1	0.3	1.0	-0.3	-0.4	-0.9	0.2	-0.5
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Body Mass Index (BMI) (2010)	0.4	0.6	2.4	-1.0	-0.6	-1.6	0.9	0.1	-0.4	0.0	0.0
Coronary Artery Disease (CAD)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Crohns Disease (2012)	0.1	0.1	0.4	-0.4	0.2	-0.1	-0.6	-0.6	-0.4	0.0	0.0
Mean Putamen Volume	0.5	0.6	1.7	0.3	0.7	-0.3	0.4	0.4	1.0	0.8	1.3
Fasting Glucose	0.9	1.1	3.4	0.8	0.5	1.8	1.4	-1.1	-0.3	-0.9	-0.4
HbA1C	0.6	0.7	3.4	-0.6	-0.3	-0.1	-1.8	0.1	-0.5	-0.9	0.7
HDL Cholesterol	0.3	0.5	2.0	0.1	-0.7	-0.0	-0.2	1.4	1.2	0.0	0.0
LDL Cholesterol	0.7	1.2	3.4	-0.3	0.9	0.1	-1.3	-1.8	-1.9	0.0	0.0
Lupus	2.5	3.8	9.4	-0.6	2.1	1.7	0.0	-3.1	-2.8	-2.3	-0.5
Neuroticism (2016)	0.9	1.3	5.7	-2.4	-0.5	-1.3	1.2	0.8	0.1	0.5	0.7
Primary Biliary Cirrhosis	1.5	2.1	4.8	-0.5	2.1	0.6	0.4	-2.2	-1.7	-2.0	0.4
Rheumatoid Arthritis	0.5	0.7	1.6	-1.0	-0.9	-0.7	0.1	1.3	1.0	0.7	0.0
Schizophrenia (2014)	0.3	0.6	3.1	1.8	0.5	-0.6	-0.2	-0.9	-0.4	-0.5	0.0
Triglycerides	0.1	0.2	0.5	0.1	-0.5	-0.4	0.7	0.7	0.7	0.0	0.0
Type 2 Diabetes (T2D) (2012)	0.1	0.2	1.2	0.0	0.0	0.0	0.0	0.0	-1.1	0.0	0.0
Ulcerative Colitis	0.2	0.3	1.5	0.3	0.1	0.7	-0.6	0.6	1.2	0.0	0.0
Blood Eosinophil Count	0.4	3.4	8.1	-0.2	-2.1	-2.9	-2.4	2.2	0.9	1.3	-1.1
Blood Platelet Count	0.7	8.3	22.1	-1.0	-2.7	-3.1	-4.7	0.6	-1.3	-2.0	-4.5
Blood Red Count	3.1	29.9	84.8	-4.5	-6.1	-8.1	-9.2	3.8	1.0	-1.4	-3.8
Blood White Count	0.9	6.4	16.1	-0.0	-3.6	-4.0	-0.1	3.1	2.9	1.8	-0.9
Heel T-Score	5.1	40.9	118.8	-1.1	10.1	10.9	6.0	-5.8	-4.7	-3.7	0.3
BMI	1.2	7.2	24.3	-4.9	-1.2	-3.8	1.6	-0.9	-1.1	-1.5	-3.2
Height	0.4	7.7	29.6	-4.2	2.6	5.4	2.3	-0.8	-0.2	-0.5	1.0
Waist Hip Ratio (WHR)	0.5	2.4	9.3	0.6	-0.8	-3.0	-1.1	1.1	1.9	1.5	-0.3
Systolic Blood Pressure	0.4	2.2	8.9	-1.6	0.1	-2.3	-0.5	-1.0	-0.1	-3.0	-0.3
Smoking Status	0.4	0.9	5.9	-0.7	-0.3	-2.4	0.3	0.6	0.3	0.3	-0.6
Allergy or Eczema	0.3	0.9	1.6	0.5	-0.4	-1.2	-0.7	1.2	1.3	0.9	0.7
Cardiovascular Disease	0.7	2.2	10.2	-0.1	-0.3	-3.2	0.5	-0.8	0.1	-1.6	-1.9
Hypothyroidism (self reported)	0.7	1.6	6.6	2.6	0.1	-0.7	0.6	0.0	0.1	0.9	-2.1
Respiratory disease	0.6	1.3	4.0	-0.0	-1.1	-2.0	0.0	1.4	1.6	0.9	-0.1
Type 2 Diabetes (T2D) (2018)	1.2	2.2	6.2	-0.8	1.1	-1.1	-0.7	-2.1	-2.5	-1.4	-1.3
Lung FEV1/FVC ratio	0.1	0.6	1.8	0.2	0.8	-0.1	0.9	-1.3	-1.1	-0.4	-0.3
Lung FVC	0.5	2.8	6.8	1.1	-1.9	0.7	0.3	2.6	1.8	2.5	-0.7
Neuroticism	0.7	1.6	5.3	-0.1	-0.1	-2.3	1.1	1.6	0.9	1.4	1.0
Chronotype (morning person)	0.7	1.5	4.7	-0.1	-1.0	-1.1	0.4	1.8	2.2	1.3	-0.2
Hair Pigment	0.1	1.7	6.7	-2.6	-0.5	-1.9	-1.3	-0.4	-0.9	-0.5	-0.2
Tanning	0.2	2.5	7.6	-1.0	-2.8	-1.4	0.2	2.0	2.0	0.9	-0.7
Hand grip strength (left)	0.8	2.2	6.0	-0.2	-0.8	1.6	2.5	1.9	1.3	1.5	-0.8
Number of treatments/medications taken	1.2	2.2	13.9	-0.5	-1.6	-3.7	0.1	0.6	1.0	0.3	0.0
Average weekly spirits intake	0.7	0.8	2.6	-0.4	1.3	-1.6	1.3	-0.1	0.2	-0.1	0.7
Sensitivity / hurt feelings	0.3	0.5	3.1	1.8	0.0	-0.1	-0.7	0.0	-0.4	0.5	0.6
Frequency of depressed mood in last 2 weeks	1.6	2.3	5.3	0.1	-0.1	-2.3	2.0	1.7	1.3	2.0	0.6
Hearing difficulty/problems: Yes	1.7	2.6	7.7	-2.8	-0.2	-0.3	0.3	-1.4	-1.7	-1.3	-2.6
Relative age of first facial hair	1.4	2.9	7.5	-0.9	-1.9	-0.7	0.0	2.0	2.7	2.5	0.1
Other serious medical condition/disability diagnosed by doctor	0.6	0.8	2.8	-0.1	-1.7	-1.2	0.5	0.7	0.3	0.9	-0.4
Ever used hormone-replacement therapy (HRT)	1.8	2.3	5.1	-1.0	0.2	-1.8	1.6	1.3	1.5	1.7	2.2
Ever had hysterectomy (womb removed)	0.7	0.8	2.2	0.8	-0.1	-0.3	-1.0	-1.1	-1.0	-1.5	-0.3
Systolic blood pressure, automated reading	1.0	2.8	10.1	-2.1	-1.5	-3.2	-0.3	-0.5	0.2	-2.2	-0.1
Eye problems/disorders: Diabetes related eye disease	0.1	0.1	0.2	0.5	0.0	0.4	0.2	-0.4	0.3	0.4	-0.0
Angina	0.8	1.1	3.3	-1.3	-0.3	-0.8	0.6	0.8	1.4	0.1	1.8
Medication for hormone replacement therapy	0.5	0.6	1.8	0.1	-1.2	-1.3	0.4	0.9	0.6	0.2	-0.5
Vitamin and mineral supplements	0.2	0.3	0.8	0.7	-0.1	0.3	-0.9	0.2	-0.7	0.1	-0.4
Supplements: Zinc	2.1	2.2	5.4	2.3	-0.2	-0.8	0.7	1.1	1.6	1.9	2.0
Medication: Co-codamol	0.8	0.9	2.0	-1.0	0.1	-0.9	-1.1	-1.2	-1.1	-1.4	0.1
Medication: Metformin	1.0	1.4	3.9	1.2	-0.8	-2.0	0.1	1.0	0.5	1.6	-1.2
Diabetes (father)	0.7	0.9	1.8	1.1	1.3	-0.3	0.6	-1.3	-0.9	-0.6	-1.0
Diabetes (mother)	0.3	0.4	1.5	-0.1	-0.3	-1.2	-1.2	0.0	-0.0	-0.1	0.3
Severe depression (siblings)	0.5	0.5	1.7	1.3	-0.6	-0.9	-0.6	0.8	0.0	0.4	0.2
Pack years adult smoking proportion	0.3	0.5	2.0	-0.7	0.3	-1.4	0.2	0.3	0.4	0.1	1.2
Impedance of leg (right)	0.7	3.3	9.1	3.0	1.9	2.3	-2.2	-0.5	0.3	0.1	1.7
Leg fat-free mass (left)	0.9	4.7	24.5	-5.0	-0.0	-0.2	2.6	-0.9	-1.3	-0.9	-1.6
Trunk fat percentage	0.8	3.1	9.6	-3.1	-0.5	-2.8	2.2	-0.6	-0.4	-0.6	-1.1
Hand grip strength (right)	1.1	3.1	7.4	1.3	0.2	2.7	2.3	1.7	1.7	2.1	0.2
Townsend deprivation index at recruitment	1.2	1.7	4.3	-1.0	1.5	-0.5	-1.0	-1.9	-2.1	-1.3	0.1
Current tobacco smoking	1.1	1.8	5.9	0.2	-2.2	-2.4	-0.7	1.2	1.0	0.4	-0.7
Average weekly fortified wine intake	0.8	1.0	3.3	0.6	-0.4	0.1	-1.8	-0.7	-0.6	-1.8	-0.3
Maternal smoking around birth	1.6	2.3	9.7	-3.1	0.7	-1.2	-1.0	-1.1	-1.6	-1.5	0.3
Fed-up feelings	0.3	0.5	1.7	-1.3	0.8	-0.5	0.4	-0.0	-0.7	0.0	0.7
Frequency of unenthusiasm / disinterest in last 2 weeks	0.6	0.7	2.5	0.3	0.5	-1.3	0.8	0.4	0.3	1.6	0.6
Relative age voice broke	0.9	1.3	3.5	-0.3	-1.9	0.0	0.3	1.2	1.8	1.3	-0.8
Taking other prescription medications	1.4	2.1	10.4	0.0	-1.7	-3.2	0.0	1.0	0.8	0.9	-1.0
Age when periods started (menarche)	1.4	3.4	14.4	3.8	-1.0	-1.0	-2.6	1.4	1.1	1.1	0.1
Bilateral oophorectomy (both ovaries removed)	0.3	0.4	0.9	-0.0	0.5	0.8	-0.4	-0.5	-0.8	-1.0	0.3
Heel bone mineral density (BMD) T-score, automated (left)	1.9	4.3	15.2	-2.4	1.6	2.6	3.9	-1.1	-0.4	-1.3	0.6
Tinnitus: Yes, but not now, but have in the past	0.6	0.7	2.5	-1.2	-1.6	-0.7	-0.4	0.0	0.4	-0.3	-0.8
Qualifications: CSEs or equivalent	0.4	0.6	1.0	0.9	-0.8	-1.0	-0.1	0.2	-0.9	1.0	-0.6
Serious illness, injury or assault to yourself	1.2	1.4	2.9	-1.7	-1.0	-1.2	0.4	-1.1	-1.0	-1.4	-1.2
High blood pressure	0.7	2.0	10.7	0.5	-0.8	-3.3	-1.0	-0.8	0.2	-1.5	-0.7
Hayfever, allergic rhinitis or eczema	0.3	0.8	2.2	1.1	0.5	-1.5	-0.1	0.4	0.3	0.8	1.3
Multivitamins +/- minerals	0.2	0.3	0.9	-0.2	0.0	-0.5	0.7	0.2	0.9	0.3	0.9
Stomach or abdominal pain in last month	3.0	3.7	14.8	-2.0	-2.8	-3.8	-1.1	1.2	0.2	0.5	-0.0
Supplements: Glucosamine	0.8	1.1	4.6	-0.9	-0.1	-0.1	2.1	0.4	1.3	0.8	0.9
Diverticular disease/diverticulitis (self-reported)	2.0	2.4	6.8	-0.4	-2.6	-1.6	-0.9	1.6	1.9	0.8	-1.4
Medication: Atenolol	2.9	3.7	8.4	-2.0	-1.4	-2.9	-0.8	1.7	2.1	1.6	2.1
Medication: Levothyroxine sodium	0.5	0.9	4.6	2.1	-0.5	-0.6	0.6	-0.2	-0.2	0.2	-1.3
Sitting height	0.9	6.4	30.0	-3.6	2.0	5.5	0.5	-1.0	-1.1	-1.2	0.4
Chronic bronchitis/emphysema (father)	1.2	1.4	7.0	-2.6	-1.0	-1.1	-0.1	0.7	0.8	-0.5	0.9
High blood pressure (mother)	1.2	1.6	7.1	1.8	0.6	-0.2	-2.7	-1.0	-0.4	-0.8	0.7
Body mass index (BMI)	1.3	5.4	18.8	-3.6	-2.1	-4.3	1.9	-0.1	-0.4	-0.2	-1.9
Impedance of leg (left)	0.7	3.6	11.7	3.4	2.2	2.3	-1.8	-0.5	0.2	0.2	1.7
Leg predicted mass (left)	0.9	4.8	25.8	-5.1	-0.1	-0.2	2.7	-0.9	-1.2	-0.9	-1.6
Trunk fat mass	0.9	3.8	15.4	-3.9	-0.3	-2.1	2.6	-0.8	-0.7	-0.8	-1.4
Waist circumference	1.2	4.3	16.9	-2.9	-2.1	-4.1	1.1	-0.3	-0.1	-0.2	-1.8
Number of incorrect matches in round	0.8	1.4	4.8	-1.5	-1.4	-2.2	0.9	0.3	0.6	0.5	-0.6
Past tobacco smoking	0.4	0.7	2.5	1.6	0.3	1.4	-0.0	-0.5	-0.3	-0.5	-0.5
Alcohol usually taken with meals	0.3	0.5	1.3	-0.0	0.0	1.0	-0.9	-0.6	-0.1	-1.1	-0.8
Nervous feelings	0.7	1.2	2.8	0.7	0.2	-0.6	0.8	1.3	1.7	1.1	1.7
Frequency of tenseness / restlessness in last 2 weeks	2.6	4.0	15.6	0.6	-1.1	-4.0	0.6	2.0	1.8	2.4	1.2
Hearing difficulty/problems with background noise	0.3	0.5	1.2	-1.0	-0.1	-0.9	-0.4	-0.4	-0.6	-0.2	-1.1
Hair/balding pattern: Pattern 2	0.4	0.5	0.9	-0.7	-0.6	-1.0	-0.4	0.9	0.1	0.8	0.6
Had menopause	0.4	0.5	1.2	-0.7	-0.9	-0.3	0.8	0.5	1.1	0.5	0.3
Had other major operations	0.2	0.3	1.0	-0.7	-0.1	0.6	0.4	-0.0	0.4	-0.2	1.0
Forced vital capacity (FVC)	0.5	1.9	7.9	-1.8	1.2	2.8	0.7	0.9	0.5	0.9	0.9
Heel bone mineral density (BMD) T-score, automated (right)	1.7	3.9	14.0	-1.6	1.8	2.9	3.7	-1.3	-0.5	-0.9	0.5
Ever unenthusiastic/disinterested for a whole week	1.6	1.9	5.2	0.2	0.5	-2.3	2.0	1.0	0.1	2.1	0.7
Qualifications: None of the above	0.7	1.5	4.7	-2.2	-0.7	-2.0	-1.5	-0.1	-0.0	-0.3	-0.0
Financial difficulties in last 2 years	1.2	1.7	9.5	-0.5	-1.2	-3.1	0.7	0.3	-0.1	1.0	-0.8
Mouth/teeth dental problems	1.2	1.8	3.6	0.5	1.4	1.9	0.6	-1.7	-1.6	-0.6	-1.5
Heart attack	0.4	0.5	1.5	-1.2	-0.4	-1.2	0.2	0.0	-0.3	-0.6	-0.7
Allergy	0.3	0.7	2.8	-0.5	0.1	1.7	0.2	-0.4	-0.7	-0.6	-1.1
Pain all over the body in last month	0.4	0.4	1.7	0.1	0.1	-1.3	-1.1	-0.4	-0.5	-0.1	-0.5
Diabetes (self-reported)	0.7	1.0	2.1	-0.4	0.5	-1.1	-0.7	-1.3	-1.5	-1.1	-1.1
Hayfever/allergic rhinitis (self-reported)	0.3	0.4	1.3	0.5	1.1	-0.7	0.5	0.2	-0.0	0.5	0.9
Medication: Ramipril	0.6	0.8	2.5	1.0	-1.5	-0.2	0.3	0.4	0.3	-0.6	-1.6
Medication: Simvastatin	0.9	1.4	5.5	-2.3	-0.4	-1.5	1.4	-0.1	0.5	-0.2	1.0
Fluid intelligence score	0.5	1.1	4.2	1.1	0.4	2.1	1.3	0.2	0.8	0.8	0.2
Illnesses of siblings	1.4	1.9	7.9	1.6	-0.6	2.8	0.8	1.4	0.7	1.2	-0.5
Neuroticism score	0.7	1.4	2.6	0.2	0.2	-1.4	1.4	1.6	1.1	1.5	1.2
Weight	0.9	4.6	23.6	-4.9	-0.5	-1.4	2.4	-0.9	-1.1	-1.0	-1.5
Impedance of arm (right)	0.3	1.2	3.0	1.2	1.1	1.7	-1.5	0.2	0.6	-0.2	1.0
Arm fat percentage (right)	1.2	4.8	16.9	-3.5	-1.7	-4.1	1.7	-0.1	-0.1	-0.4	-1.6
Trunk fat-free mass	0.5	2.8	16.1	-4.0	-0.1	1.2	1.5	-0.6	-1.0	-0.4	-1.0
Hip circumference	1.0	4.1	18.2	-4.3	-0.7	-2.1	1.9	-1.0	-1.4	-1.3	-1.3
Time employed in main current job	1.1	1.3	3.7	-1.0	-0.4	-1.9	1.0	0.6	1.5	0.1	1.2
Alcohol intake versus 10 years previously	1.3	1.9	4.3	0.1	1.2	1.1	-0.9	-1.7	-2.1	-2.0	-0.8
Father’s age at death	1.0	1.4	4.9	0.8	1.3	2.2	0.6	-1.0	-1.1	-0.9	0.5
Worrier / anxious feelings	0.6	1.2	2.6	1.6	0.1	-0.0	0.1	1.4	1.1	1.4	1.3
Frequency of tiredness / lethargy in last 2 weeks	0.7	1.1	5.4	0.9	0.5	-2.3	0.2	-0.9	-0.8	-0.3	-0.7
Falls in the last year	2.5	3.3	13.1	-2.1	-2.4	-3.6	0.3	1.2	1.0	0.7	-0.3
Hair/balding pattern: Pattern 3	0.4	0.6	1.3	0.9	-0.3	-0.2	-0.4	1.0	1.2	1.0	-0.4
Number of live births	0.9	1.2	4.9	-1.1	-1.2	-2.2	-0.4	0.3	0.1	-1.3	-0.4
Forced expiratory volume in 1-second (FEV1)	0.5	1.7	7.3	-1.5	1.5	2.7	0.8	-0.3	-0.8	-0.1	0.1
Pulse rate	1.2	2.1	4.0	-0.1	-1.6	-1.2	1.3	1.8	2.0	1.8	0.1
Happiness	0.5	0.6	1.9	0.6	1.2	0.0	-0.2	-0.9	-1.4	-0.7	0.2
Noisy workplace	0.9	1.1	7.7	-0.4	0.3	-2.8	0.9	-0.3	-0.3	0.3	0.3
Qualifications: A levels/AS levels or equivalent	0.5	1.2	2.7	1.6	1.6	1.5	-0.4	-0.5	-0.4	0.3	1.0
Serious illness, injury or assault of a close relative in last 2 years	0.2	0.3	0.9	0.7	0.4	1.0	0.2	0.3	0.4	-0.3	0.5
Mouth/teeth dental problems: Dentures	1.3	2.2	6.7	-1.4	-2.6	-2.3	-1.1	0.9	0.7	-0.1	-0.9
Asthma	0.4	0.7	2.3	-0.3	0.1	-1.0	-0.3	0.8	1.2	0.5	1.5
Medication: Ibuprofen (e.g. Nurofen)	1.5	1.9	3.9	-1.3	0.5	-2.0	0.6	-1.9	-1.3	-1.5	-1.5
Medication: Cholesterol lowering	0.5	0.8	4.5	-0.1	-0.4	-2.1	0.5	0.3	0.7	0.3	1.0
Depression (self-reported)	0.4	0.5	1.0	1.0	1.0	-0.3	0.7	0.6	0.1	1.0	0.1
Medication: Lansoprazole	1.8	2.0	6.1	-0.4	-1.6	-2.5	-0.4	1.8	1.2	1.0	1.4
Prospective memory result	0.6	0.7	4.5	2.1	0.3	-0.1	-0.9	0.1	-0.4	0.4	-0.0
Lung cancer (father)	1.0	1.1	3.4	-0.9	-1.8	-1.1	-1.8	0.3	0.1	0.3	-0.5
Illnesses of mother	0.8	1.0	2.4	-1.6	0.1	-0.4	1.5	0.9	0.4	1.0	-0.9
Forced expiratory volume in 1-second (FEV1), Best measure	0.6	1.9	6.7	-2.6	1.2	2.2	0.6	-0.3	-1.0	0.0	-0.8
Pulse wave Arterial Stiffness index	0.3	0.3	0.9	-0.7	0.5	-0.3	-0.9	-0.4	-0.1	-0.2	0.9
Impedance of arm (left)	0.2	1.1	2.2	1.0	1.5	1.1	-1.1	0.2	0.7	-0.3	1.4
Arm fat mass (right)	1.1	4.4	16.6	-4.1	-1.2	-3.1	2.0	-0.5	-0.7	-0.5	-1.6
Trunk predicted mass	0.5	2.7	16.0	-4.0	-0.2	1.0	1.5	-0.5	-1.0	-0.4	-0.9
Standing height	0.8	7.8	34.6	-3.5	2.9	5.9	1.2	-1.5	-1.2	-1.4	0.5
Length of working week for main job	2.0	2.2	4.7	-1.6	1.6	-0.9	2.2	-1.9	-1.8	-0.6	0.3
Exposure to tobacco smoke at home	0.5	0.5	1.6	0.7	-1.3	-0.2	0.8	0.1	0.1	0.4	-1.0
Breastfed as a baby	1.7	2.1	9.1	1.6	-0.8	0.2	-3.0	-0.9	-0.7	-1.5	-1.2
Tense / ‘highly strung’	2.0	3.3	7.6	1.5	-0.2	-1.8	0.9	2.4	1.9	2.8	1.9
Seen doctor (GP) for nerves, anxiety, tension or depression	1.6	2.4	5.1	1.7	0.4	-1.8	0.8	1.6	1.1	2.3	1.8
Hair/balding pattern: Pattern 4	0.8	1.9	8.1	2.8	1.5	0.4	0.9	-1.1	-0.8	-1.5	-0.3
Birth weight of first child	0.5	1.0	2.2	0.4	-1.2	1.2	-0.8	1.5	1.2	0.6	-0.3
Peak expiratory flow (PEF)	0.9	2.0	4.4	-2.0	1.6	2.1	0.1	-1.3	-1.2	-1.2	-0.4
Pulse wave reflection index	0.3	0.3	1.2	0.1	0.6	0.5	-0.5	-1.1	-0.6	-0.5	0.3
Ever highly irritable/argumentative for 2 days	1.4	1.7	10.9	0.5	-0.9	-3.3	0.2	0.4	-0.0	1.1	-0.5
Loud music exposure frequency	1.7	1.8	3.8	0.6	1.4	1.7	0.0	-1.5	-1.9	-1.2	-1.4
Qualifications: O levels/GCSEs or equivalent	0.7	1.1	2.4	1.4	0.3	1.6	0.6	1.1	1.3	0.7	1.1
Mouth/teeth dental problems: Bleeding gums	1.7	2.2	9.7	-0.6	1.1	0.4	1.4	0.9	1.2	1.3	3.1
Blood clot in the leg (DVT)	1.0	1.2	5.7	1.1	-0.1	-0.6	-0.2	1.0	1.1	0.8	2.4
Medication: Paracetamol	0.6	1.0	5.1	-1.1	-0.8	-2.2	-0.6	-0.1	-0.2	-0.6	0.2
Headache pain in last month	0.3	0.5	1.5	-0.7	-0.7	-1.2	-0.1	0.9	0.4	0.5	0.5
Medication for cholesterol, blood pressure or diabetes	0.3	0.5	2.7	0.1	-0.1	1.6	0.5	0.5	0.0	0.4	-0.6
Glaucoma (self-reported)	0.1	0.1	0.5	0.7	-0.2	-0.1	-0.0	0.1	0.1	0.3	-0.0
Gout (self-reported)	0.9	1.2	3.6	-0.0	0.1	1.9	1.8	0.4	1.3	0.7	0.2
Hypothyroidism/myxoedema (self-reported)	0.6	1.2	6.1	2.5	-0.1	-0.0	0.8	-0.4	-0.1	0.4	-1.6
Medication: Amlodipine	0.2	0.3	1.0	-0.6	-0.4	-1.0	-0.1	-0.4	0.0	-0.7	-0.2
Medication: Ventolin 100micrograms inhaler	1.0	1.2	2.8	-0.6	-0.6	-0.4	-0.0	1.5	1.7	1.1	1.7
Birth weight	1.3	2.8	12.6	0.9	2.1	3.5	-0.9	-0.6	-0.1	0.3	1.8
Chronic bronchitis/emphysema (mother)	0.1	0.1	0.6	0.2	-0.3	-0.8	0.1	0.2	0.2	0.4	-0.2
High blood pressure (siblings)	0.7	1.0	5.1	-0.6	0.6	-2.3	-0.3	-0.5	0.1	-0.1	1.2
Forced vital capacity (FVC), Best measure	0.6	2.3	7.8	-2.8	1.1	2.7	0.3	0.9	0.1	1.1	0.1
Body fat percentage	0.8	3.3	10.3	-3.0	-0.8	-3.2	2.0	-0.7	-0.4	-0.6	-1.4
Leg fat percentage (right)	0.9	3.1	12.5	-2.4	-1.3	-3.5	0.9	-0.9	-0.7	-0.8	-1.6
Arm fat-free mass (right)	0.6	3.3	16.8	-4.1	0.1	0.4	2.1	-1.0	-1.4	-0.7	-1.1
Exposure to tobacco smoke outside home	0.9	1.3	3.9	0.5	0.0	-0.5	-1.1	-1.5	-2.0	-1.2	-0.7
Comparative body size at age 10	0.3	1.0	3.3	-0.6	-0.5	-1.4	1.8	0.2	0.3	0.9	-0.9
Number of full brothers	3.9	4.9	20.4	-1.8	-2.9	-4.5	-1.0	0.8	0.4	0.6	-2.2
Worry too long after embarrassment	0.7	1.1	2.8	-0.0	1.7	0.8	1.4	-1.3	-1.3	-0.1	-0.6
Seen a psychiatrist for nerves, anxiety, tension or depression	1.0	1.3	2.8	-0.2	1.3	-1.6	1.7	0.0	-0.3	1.5	1.1
Wheeze or whistling in the chest in last year	1.0	1.8	7.9	-0.6	0.9	-2.8	1.8	-0.0	0.2	0.6	1.4
Number of children fathered	0.3	0.4	0.9	-0.9	-0.6	-0.1	-0.9	-0.5	-0.1	-0.6	-0.3
Reason for reducing amount of alcohol drunk: Health precaution	2.4	2.8	5.5	-1.2	-1.3	-1.8	1.1	1.8	2.3	1.9	1.6
Age at first live birth	0.8	1.3	3.7	1.9	-0.6	0.4	1.4	1.1	1.1	1.1	-0.8
Pulse wave peak to peak time	0.2	0.3	1.0	0.5	-0.3	0.5	0.8	0.2	-0.1	-0.1	-1.0
Health satisfaction	1.8	2.3	5.4	0.1	-2.3	-2.1	0.0	1.9	1.4	1.7	-0.0
Shortness of breath walking on level ground	0.5	0.6	1.3	-1.1	-1.1	-0.9	-0.6	0.4	0.6	0.7	-0.4
Qualifications: College or University degree	0.4	1.3	4.3	-0.4	1.8	2.1	1.3	-0.5	-0.2	-0.1	1.0
Eye problems/disorders: None of the above	0.6	0.7	2.9	-0.2	-0.5	-1.7	1.1	0.6	0.5	0.7	0.1
Mouth/teeth dental problems: Loose teeth	1.2	1.4	5.4	0.0	1.1	-1.7	0.1	0.2	0.3	1.2	2.3
Emphysema/chronic bronchitis	0.1	0.1	0.3	0.2	0.1	0.1	0.3	-0.6	-0.2	0.0	0.1
Medication for pain relief, constipation, heartburn	1.6	2.7	18.3	1.1	1.3	4.3	-0.5	-0.3	-0.4	-0.4	0.3
Neck or shoulder pain in last month	0.6	0.8	2.1	-1.3	-0.8	-1.5	0.0	0.6	0.4	0.1	1.4
Medication: Blood pressure	0.4	0.7	1.6	-0.5	0.9	-0.8	-0.9	-1.2	-0.6	-0.8	0.7
Angina (self-reported)	1.1	1.4	4.2	-1.1	-0.1	-1.0	0.8	1.0	1.6	0.5	2.0
Migraine (self-reported)	0.3	0.4	0.9	-0.8	0.3	0.1	-0.1	-0.6	-0.8	-0.9	1.0
Medication: Ibuprofen	1.6	1.9	4.2	-0.8	0.4	-2.1	0.0	-1.9	-1.4	-1.7	-1.4
Medication: Allopurinol	0.7	1.0	3.8	0.1	1.0	1.9	1.2	-0.0	0.7	0.2	0.9
Medication: Omeprazole	2.6	3.1	9.0	-0.6	-2.9	-3.0	0.4	1.5	1.2	1.2	-1.4
Medication: Seretide 50 evohaler	1.3	1.5	4.2	-0.1	-1.0	-2.0	0.2	1.6	1.4	1.1	0.9
Mean time to correctly identify matches	0.7	1.3	4.8	-2.0	-0.4	-0.1	0.2	-1.1	-0.7	-2.2	0.1
Heart disease (mother)	0.5	0.6	2.7	0.3	0.8	0.3	0.5	-0.7	-0.1	-0.7	1.7
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.7	0.9	5.4	0.8	0.8	-0.1	2.3	-0.4	0.0	0.4	0.4
Whole body fat mass	0.9	3.9	15.6	-4.0	-0.8	-2.6	2.1	-0.7	-0.7	-0.7	-1.6
Leg fat mass (right)	1.0	3.9	14.7	-3.8	-0.8	-2.6	1.7	-1.2	-1.1	-0.9	-1.6
Arm predicted mass (right)	0.7	3.4	16.9	-4.1	0.2	0.6	2.3	-1.0	-1.3	-0.6	-1.1
Pulse rate, automated reading	0.9	3.0	4.6	0.1	-2.1	-1.7	2.0	1.9	2.0	1.7	-1.4
Alcohol intake frequency.	0.6	1.5	3.1	1.2	1.8	1.5	0.2	-1.2	-1.1	-0.6	1.3
Comparative height size at age 10	0.8	4.3	10.2	-3.2	1.8	3.0	0.8	-1.8	-1.4	-2.4	-0.7
Number of full sisters	0.4	0.5	1.1	0.1	0.4	0.4	-0.9	-1.0	-0.8	-1.0	0.6
Suffer from ‘nerves’	1.7	2.6	6.0	1.0	-0.7	-0.9	0.3	2.2	2.3	2.4	1.6
Overall health rating	0.8	1.7	12.0	-0.1	-1.1	-3.5	0.3	0.2	0.1	0.7	-0.3
Chest pain or discomfort	0.8	1.2	5.4	-2.3	0.1	-1.4	1.2	-0.4	-0.5	-0.4	0.4
Had major operations	0.4	0.4	1.2	0.4	-0.7	-1.1	0.8	0.5	-0.1	0.4	-0.8
Age at last live birth	0.5	0.7	2.5	1.2	-0.4	-1.6	1.0	0.6	0.4	0.3	0.3
Family relationship satisfaction	0.3	0.4	1.7	1.3	0.8	0.5	-0.2	-0.3	-0.4	0.3	0.2
Leg pain on walking	1.0	1.2	3.8	-0.7	1.1	-2.0	-0.5	-0.8	-1.0	0.5	1.5
Qualifications: NVQ or HND or HNC or equivalent	0.2	0.3	1.5	1.2	0.3	-0.0	-0.5	-0.1	0.1	0.2	0.1
Commuting to job workplace: Car/motor vehicle	0.7	0.9	3.5	-1.0	0.1	-0.7	1.9	-0.2	0.9	-0.1	1.0
Illness, injury, bereavement, stress in last 2 years	0.1	0.2	0.7	-0.0	0.3	0.6	-0.8	-0.1	-0.2	0.1	0.2
Medication: Aspirin	0.7	0.9	3.0	-0.3	-0.8	-1.7	-0.2	0.9	1.3	0.7	0.4
Supplements: Vitamin C	0.8	1.0	4.1	0.7	-0.5	-2.0	0.3	0.2	0.8	1.1	1.1
Knee pain experienced in last month	0.6	0.9	3.3	-0.7	0.6	-1.8	-0.1	-0.6	-0.6	-0.3	1.5
Hypertension (Self-reported)	0.5	1.5	8.4	0.6	-0.8	-2.9	-0.9	-0.5	0.6	-0.9	-0.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	4.5	5.3	13.7	-1.8	-3.7	-3.3	0.4	2.6	2.1	0.6	-1.6
Illnesses of father: Heart disease	0.3	0.4	1.0	0.5	-0.3	-0.8	0.8	1.0	0.4	0.5	-0.6
Illnesses of siblings: Diabetes	0.7	0.8	3.2	-1.8	0.2	-1.7	-0.3	-0.4	-0.1	-0.2	0.4
Smoking status: Previous	0.2	0.3	1.3	-1.1	0.3	-0.6	0.3	0.1	-0.1	0.3	0.5
Forced expiratory volume in 1-second (FEV1), predicted	1.0	2.1	4.9	-1.6	1.8	2.2	1.2	-1.0	-1.2	-1.3	0.7
Whole body fat-free mass	0.6	3.6	19.9	-4.5	-0.1	0.6	2.0	-0.8	-1.2	-0.6	-1.3
Leg fat-free mass (right)	0.8	4.4	22.3	-4.7	0.0	-0.2	2.8	-0.8	-1.3	-0.7	-1.6
Arm fat percentage (left)	1.3	5.3	19.3	-3.7	-1.5	-4.4	2.1	-0.1	-0.0	-0.5	-1.4
Average weekly red wine intake	0.8	1.2	3.0	-0.8	-1.7	-0.6	-1.2	0.4	0.8	-0.8	-1.5
Handedness (chirality/laterality): Left-handed	0.2	0.3	1.0	-0.7	-0.2	1.0	-0.5	0.1	-0.2	-0.1	-0.6
Mood swings	0.2	0.4	1.2	-0.7	-0.5	-0.8	-0.4	0.2	-1.1	-0.3	-0.2
Loneliness, isolation	1.7	2.4	5.4	0.1	-0.7	-0.9	2.3	1.8	1.8	2.2	1.0
Long-standing illness, disability or infirmity	0.7	1.0	2.5	0.4	-1.3	-1.6	0.2	1.3	0.9	1.0	0.4
Ever had bowel cancer screening	2.0	2.3	5.5	-1.0	-0.3	-0.8	1.0	1.7	2.2	1.5	2.3
Diabetes diagnosed by doctor	0.8	1.3	2.9	-0.1	0.4	-1.4	-0.8	-1.7	-1.6	-1.1	-1.1
Ever had stillbirth, spontaneous miscarriage or termination	1.1	1.2	6.5	0.2	0.0	-2.5	1.3	0.4	0.7	0.5	0.5
Friendships satisfaction	0.4	0.4	1.0	1.0	-0.1	0.0	-0.7	-0.2	-0.9	1.0	-0.3
Qualifications: nursing, teaching	0.5	0.7	1.7	0.1	-0.7	0.5	1.1	1.0	1.3	1.2	-0.2
Commuting to job workplace: Walk	0.6	0.6	1.3	-0.3	0.9	1.1	0.9	-0.4	-1.0	-0.3	-0.8
Eye problems/disorders: Cataract	1.9	2.2	6.5	-0.4	1.9	2.5	-1.3	-1.5	-1.2	-1.3	0.8
Mouth/teeth dental problems: Mouth ulcers	0.5	0.8	1.8	0.2	-0.9	-1.2	-0.3	1.3	1.1	0.6	0.9
Medication for cholesterol	0.9	1.4	2.7	-0.7	1.6	1.4	1.6	-0.1	0.3	1.2	1.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.9	1.1	6.2	0.0	0.4	0.9	2.5	-0.5	-0.3	1.0	0.3
Back pain experienced in last month	0.7	1.1	3.9	-0.9	-1.4	-2.0	-0.8	0.6	0.6	-0.0	0.3
Mineral and other dietary supplements	0.4	0.6	3.2	0.8	0.0	0.4	-0.2	0.2	-0.8	0.2	-1.8
Breast cancer (self-reported)	0.8	0.9	2.4	-1.0	0.5	1.2	1.1	-1.0	-0.2	-1.6	-0.5
Asthma (self-reported)	0.4	0.7	2.5	0.1	0.3	-1.0	-0.5	0.7	1.1	0.6	1.6
Osteoporosis (self-reported)	3.5	4.3	8.6	2.0	-2.8	-2.3	-0.9	2.3	2.9	1.7	0.2
Osteoarthritis (self-reported)	0.4	0.5	1.5	0.6	-0.6	-0.5	0.7	0.5	1.2	0.7	0.4
Medication: Aspirin	0.8	1.0	2.6	-0.1	-0.5	-1.6	0.6	1.1	1.6	0.9	0.8
Medication: Gliclazide	1.0	1.1	2.5	0.4	0.3	-1.5	-0.9	-0.9	-1.6	0.0	-1.5
Illnesses of father: None of the above (group 1)	0.7	0.8	2.0	-0.2	-1.0	1.4	-1.4	1.0	0.7	0.3	-0.0
Smoking status: Current	0.6	1.0	3.7	0.0	-1.5	-1.9	-0.7	0.9	0.7	0.2	-0.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.4	3.0	7.9	-1.4	-1.5	0.3	0.8	2.8	2.5	2.2	-0.4
Whole body water mass	0.6	3.7	20.9	-4.6	-0.0	0.6	2.0	-0.8	-1.3	-0.6	-1.2
Leg predicted mass (right)	0.8	4.4	22.3	-4.7	0.1	-0.1	2.7	-0.8	-1.3	-0.8	-1.6
Arm fat mass (left)	1.1	4.6	16.1	-4.0	-1.2	-3.4	2.3	-0.2	-0.5	-0.3	-1.5
Number of self-reported non-cancer illnesses	2.0	3.5	11.0	-0.4	-1.1	-3.3	1.5	1.9	2.5	1.2	1.5
Average weekly champagne plus white wine intake	0.9	1.2	3.4	-0.6	1.9	0.5	0.5	-1.4	-1.7	-0.8	0.3
Miserableness	0.4	0.7	1.5	-1.0	0.8	-0.8	1.2	-0.4	-1.0	-0.5	-0.6
Guilty feelings	0.9	1.3	4.1	1.1	1.5	-0.8	0.3	0.5	-0.1	1.4	2.0
Wears glasses or contact lenses	0.9	1.0	2.3	-0.2	-1.1	-1.4	-0.4	1.5	1.3	0.8	0.6
Ever taken oral contraceptive pill	1.4	1.6	4.9	1.7	1.3	2.2	0.7	-0.2	-0.2	0.8	1.4
Hearing aid user	0.6	0.7	5.3	-2.3	-0.1	-0.2	-0.4	-0.1	0.2	0.1	0.2
Mother’s age at death	1.2	1.5	4.8	1.4	1.5	2.2	-1.1	-0.8	-0.1	-0.4	1.1
Financial situation satisfaction	1.0	1.2	3.6	1.9	1.0	-0.1	-0.6	-1.1	-1.8	-0.2	0.3
Tinnitus: Yes, now most or all of the time	0.6	0.7	2.5	0.7	-1.1	-1.6	-1.0	0.3	-0.2	0.0	-0.7
Commuting to job workplace: Public transport	2.1	2.5	5.6	2.1	1.0	2.4	-2.0	-1.3	-1.4	-1.0	-0.8
Eye problems/disorders: Glaucoma	0.1	0.1	0.5	0.6	0.1	0.7	0.1	0.2	0.0	0.3	-0.0
Medication: Blood pressure	0.5	0.9	2.8	0.1	-0.6	-0.9	-0.5	-0.8	-0.5	-1.7	-1.5
Pain type(s) experienced in last month: Hip pain	1.4	1.7	6.8	-2.0	0.8	-2.6	0.5	-0.8	-0.2	-0.1	1.1
Supplements: Fish oil (including cod liver oil)	0.4	0.5	2.0	-0.9	-0.0	-0.4	-0.7	-0.3	0.3	-0.4	1.4
High cholesterol (Self-reported)	1.1	1.9	5.9	0.0	-1.4	-2.4	1.8	1.1	1.7	0.4	0.3
Medication: Bendroflumethiazide	0.6	1.0	2.6	0.7	-1.5	-0.8	-0.2	0.7	1.0	-0.4	-1.6
Medication: Paracetamol	0.5	0.8	2.8	-0.8	-0.7	-1.7	-0.9	-0.2	-0.6	-1.2	-0.0
Medication: Lisinopril	1.1	1.4	4.5	-0.6	0.0	-0.3	-1.3	-1.2	-1.4	-2.1	-1.0
Medication: Atorvastatin	0.3	0.4	1.5	0.7	0.6	-0.3	1.2	-0.6	-0.2	0.1	-0.8
Illnesses of father: High blood pressure	1.3	1.6	3.5	1.0	1.2	-1.1	0.5	-1.9	-1.6	-1.5	-0.0
Alcohol drinker status: Never	0.1	0.1	0.3	-0.2	-0.1	0.2	0.6	0.2	-0.1	0.4	0.1
Ever smoked	0.4	0.7	1.5	-1.2	-0.7	-1.0	-0.2	1.0	0.7	0.8	0.4
Basal metabolic rate	0.7	3.9	21.4	-4.6	-0.1	0.1	2.2	-0.8	-1.3	-0.7	-1.4
Leg fat percentage (left)	0.8	3.0	12.2	-2.1	-1.1	-3.5	1.2	-0.9	-0.7	-0.8	-1.6
Arm fat-free mass (left)	0.6	2.8	14.0	-3.7	-0.1	0.3	1.9	-0.9	-1.5	-0.5	-1.3
Number of operations (self-reported)	0.3	0.5	1.4	0.5	-0.3	-1.2	-0.6	-0.1	-0.8	-0.9	-0.5
Average weekly beer plus cider intake	1.1	1.7	3.3	-1.2	-0.8	-1.8	0.2	1.7	1.5	1.4	0.8
Irritability	1.1	1.8	5.8	0.1	1.5	0.8	2.4	0.9	0.3	1.8	1.2
Risk taking	0.6	0.9	3.3	-1.2	-1.2	-1.8	-0.5	0.1	-0.4	-0.4	-0.5
Ever had prostate specific antigen (PSA) test	0.9	1.0	4.8	-0.5	0.6	-0.4	-0.6	-0.7	-0.2	-1.4	2.2
Fractured/broken bones in last 5 years	1.0	1.4	4.5	1.0	-0.8	-2.1	0.1	0.9	0.8	1.6	0.9
Age started oral contraceptive pill	0.4	0.5	1.3	-0.9	0.3	1.1	1.1	-0.6	-0.1	-0.3	-0.0
Diastolic blood pressure, automated reading	0.5	1.6	6.8	-0.3	-1.4	-2.6	-0.5	-0.5	-0.2	-1.6	-1.1
Ever depressed for a whole week	1.4	1.7	7.1	-0.4	-0.1	-2.0	2.7	0.5	0.1	1.5	-0.2
Unable to work because of sickness or disability	0.7	1.0	4.3	-0.3	-1.5	-2.1	0.0	-0.2	-0.2	-0.5	-0.9
Commuting to job workplace: Cycle	0.5	0.6	1.8	-0.6	0.0	1.2	1.3	0.1	0.6	-0.9	0.0
Myopia	1.3	1.9	5.5	0.6	2.4	1.6	0.1	-1.5	-1.2	-1.6	-0.4
Vascular/heart problems diagnosed by doctor	0.9	2.6	14.4	-0.6	1.6	3.8	1.0	0.2	-0.7	1.3	0.5
Cholesterol lowering medication	0.6	0.9	3.4	-1.4	-1.1	-1.9	-0.2	0.3	0.2	-0.1	-0.1
Medication: Omeprazole (e.g. Zanprol)	4.7	5.7	15.1	-0.4	-3.8	-3.9	0.5	2.4	2.2	1.9	-1.3
Pain experienced in last month	1.1	1.9	9.1	1.2	-0.3	3.0	-0.0	-0.3	0.1	-0.3	-2.0
Supplements: Calcium	0.7	0.8	1.8	0.9	0.5	1.0	-1.1	0.2	0.9	0.5	1.3
Basal cell carcinoma (self-reported)	0.3	0.4	2.3	-1.5	0.4	0.2	-0.6	0.2	0.2	-0.0	0.2
Heart attack/myocardial infarction (self-reported)	0.6	0.7	2.4	-1.5	-0.7	-1.5	0.2	0.0	-0.2	-0.5	-0.6
Deep venous thrombosis (DVT) (self-reported)	1.2	1.6	6.4	1.1	-0.3	-0.9	-0.1	1.2	1.4	0.8	2.5
Heart disease (siblings)	1.1	1.4	8.5	1.0	0.0	-2.9	1.0	-0.0	0.6	0.3	0.5
Alcohol drinker status: Previous	1.0	1.1	3.1	-1.0	-0.6	0.3	0.6	1.2	1.3	1.0	1.8
Pack years of smoking	0.5	0.8	2.8	-0.5	0.1	-1.5	0.1	0.5	0.7	0.3	1.7
Impedance of whole body	0.5	2.7	6.6	2.6	2.1	2.3	-1.3	-0.2	0.5	-0.2	1.7
Leg fat mass (left)	0.9	3.7	13.0	-3.6	-0.6	-2.6	2.1	-1.1	-1.0	-0.7	-1.5
Arm predicted mass (left)	0.6	3.0	15.8	-4.0	-0.2	0.6	1.4	-1.1	-1.6	-0.7	-1.3