TWAS hub - POM121B

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Visceral Omentum	0.1000	0.0500	8.3e-03	0.101	NA	0.067	NA	0.077	6.4e-06	NA	2.3e-04	NA	7.9e-05
2	GTEx	Artery Aorta	0.1220	0.0510	1.5e-04	0.036	NA	0.067	NA	0.080	4.5e-03	NA	1.4e-04	NA	3.6e-05
3	GTEx	Artery Tibial	0.0682	0.0349	2.6e-03	0.002	NA	0.006	NA	0.004	2.0e-01	NA	1.1e-01	NA	1.6e-01
4	GTEx	Brain Hypothalamus	0.1660	0.0720	5.3e-03	0.148	NA	0.014	NA	0.059	2.5e-04	NA	1.5e-01	NA	1.7e-02
5	GTEx	Cells Transformed fibroblasts	0.0610	0.0300	2.4e-03	0.025	NA	-0.003	NA	0.010	4.9e-03	NA	6.2e-01	NA	5.8e-02
6	GTEx	Esophagus Mucosa	0.1430	0.0510	1.3e-05	0.021	NA	0.095	NA	0.071	1.5e-02	NA	7.0e-07	NA	1.8e-05
7	GTEx	Esophagus Muscularis	0.0680	0.0370	6.3e-03	-0.005	NA	0.004	NA	0.001	9.9e-01	NA	1.7e-01	NA	2.8e-01
8	GTEx	Heart Atrial Appendage	0.0760	0.0390	6.2e-03	0.030	NA	0.036	NA	0.032	1.6e-02	NA	9.7e-03	NA	1.4e-02
9	GTEx	Muscle Skeletal	0.0568	0.0335	3.3e-03	0.022	NA	0.028	NA	0.009	2.9e-03	NA	8.0e-04	NA	3.8e-02
10	GTEx	Nerve Tibial	0.1365	0.0485	1.4e-05	0.014	NA	0.063	NA	0.050	3.3e-02	NA	2.8e-05	NA	1.9e-04
11	GTEx	Thyroid	0.1180	0.0500	2.9e-04	0.011	NA	0.012	NA	0.026	4.7e-02	NA	3.7e-02	NA	4.3e-03
12	GTEx	Whole Blood	0.0470	0.0260	4.5e-03	0.032	NA	0.022	NA	0.032	6.1e-04	NA	3.8e-03	NA	6.1e-04
13	ROSMAP	Brain Pre-frontal Cortex	0.0906	0.0377	1.6e-04	0.023	0.041	0.033	0.039	0.015	5.2e-04	4.6e-06	4.2e-05	7.2e-06	4.2e-03

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13
Triglycerides	16.3	26.7	130.0	1.2	7.6	4.8	-1.0	3.9	-1.2	2.2	9.1	3.6	-0.8	1.9	3.6	11.4
Respiratory disease	4.2	9.4	16.5	-3.1	-3.5	-4.1	-2.6	-1.6	-2.8	-3.7	-2.6	-2.5	-3.4	-3.9	-2.3	-2.8
Wheeze or whistling in the chest in last year	4.0	7.2	12.4	-2.6	-2.9	-3.5	-1.9	-1.2	-2.9	-3.3	-1.9	-3.0	-3.0	-2.9	-1.7	-3.1
Neck or shoulder pain in last month	3.7	5.2	10.2	-1.5	-1.9	-2.6	-2.6	-1.2	-2.5	-2.3	-1.8	-1.7	-2.5	-3.1	-1.9	-3.2
LDL Cholesterol	3.5	5.6	9.4	-1.4	-2.6	-2.4	-2.0	-2.0	-3.0	-2.9	-2.6	-1.8	-2.3	-3.1	-2.5	-1.3
Asthma	3.2	6.2	13.8	-3.0	-3.1	-3.7	-1.3	-1.5	-2.2	-3.4	-2.0	-2.0	-2.6	-2.9	-1.8	-1.2
Medication: Ventolin 100micrograms inhaler	3.1	3.9	7.2	-1.6	-2.2	-2.2	-1.5	-1.8	-2.2	-2.7	-2.2	-1.4	-1.9	-2.7	-2.1	-0.0
Gout (self-reported)	3.0	4.1	10.8	0.2	3.3	1.9	-0.1	2.5	0.7	1.9	3.3	1.8	0.0	1.5	2.4	2.4
Ever unenthusiastic/disinterested for a whole week	2.9	3.6	7.2	2.1	2.0	2.1	1.2	1.1	2.3	2.7	2.3	1.0	2.4	2.2	1.3	0.2
Asthma (self-reported)	2.8	5.6	12.5	-2.6	-3.0	-3.5	-1.4	-1.5	-1.9	-3.1	-2.1	-1.8	-2.3	-2.8	-1.9	-1.4
Leg pain on walking	2.6	3.2	6.5	0.1	1.9	1.8	0.6	2.2	1.6	1.7	2.5	1.9	1.5	1.8	2.3	1.7
Mouth/teeth dental problems: Bleeding gums	2.5	3.2	10.7	-1.9	-0.8	-1.4	-1.8	-0.7	-3.3	-1.9	-0.8	-1.3	-2.9	-2.4	-1.2	0.3
Frequency of unenthusiasm / disinterest in last 2 weeks	2.4	3.2	14.0	-0.9	-0.7	-2.0	-1.5	-0.0	-1.8	-1.2	-0.9	-3.7	-2.5	-1.4	-0.4	-2.4
Impedance of leg (left)	2.4	11.5	28.8	1.4	5.4	4.4	-0.1	4.7	2.8	3.7	3.7	2.2	2.1	3.1	4.5	1.4
Number of children fathered	2.4	2.7	10.4	0.4	1.2	1.9	0.9	1.3	1.6	1.4	1.6	1.2	2.0	1.6	1.5	3.2
Frequency of tiredness / lethargy in last 2 weeks	2.3	3.7	7.8	-1.8	-1.2	-2.4	-2.2	-0.1	-2.4	-1.6	-0.2	-2.6	-2.8	-2.3	-0.8	-2.2
Medication: Blood pressure	2.3	4.0	14.9	-0.1	2.3	2.3	-1.4	2.4	0.9	1.0	2.5	1.9	1.6	0.3	1.9	3.9
Alcohol intake frequency.	2.3	5.2	12.3	1.6	3.5	2.7	0.5	2.0	1.8	2.3	3.3	2.2	1.3	2.1	2.1	2.8
Impedance of leg (right)	2.2	10.5	27.4	0.9	5.2	4.1	-0.4	4.7	2.3	3.3	3.9	2.3	1.5	2.7	4.5	1.8
Medication: Atenolol	2.2	2.8	5.2	0.5	1.9	1.9	1.0	1.8	1.6	1.6	2.3	1.0	1.7	1.9	2.0	1.4
Guilty feelings	2.1	3.2	6.2	2.0	2.1	1.9	0.6	1.6	2.5	2.5	1.2	-0.1	2.1	2.1	1.8	0.7
Ever taken oral contraceptive pill	2.1	2.4	3.9	-1.2	-1.7	-1.8	-0.1	-1.7	-1.9	-2.0	-1.7	-1.5	-1.7	-1.5	-1.6	-0.7
Birth weight	2.0	4.3	18.7	-0.8	-1.2	-2.2	-2.6	0.4	-1.1	-0.7	-1.8	-3.5	-1.7	-1.8	-0.3	-4.3
Commuting to job workplace: Public transport	2.0	2.4	7.3	0.5	-1.0	-1.4	0.1	-1.7	-1.3	-0.6	-2.3	-2.0	-1.9	-0.7	-1.6	-2.7
Number of full brothers	1.9	2.4	5.5	0.6	1.3	1.6	0.9	0.9	1.4	1.3	2.0	2.3	1.7	1.4	1.3	2.2
Impedance of whole body	1.9	9.7	29.6	0.7	5.4	3.6	-0.2	4.6	1.9	3.2	4.0	1.9	0.4	2.8	4.4	1.4
Depression (Nagel 2018)	1.8	2.7	10.7	-1.3	-1.2	-2.0	0.0	-0.2	-1.6	-1.2	-1.1	-3.3	-2.2	-0.6	-0.3	-2.6
Allergy	1.8	4.1	8.6	0.9	2.0	2.5	2.6	1.4	1.7	2.2	2.1	1.8	1.6	2.9	2.1	1.7
Loud music exposure frequency	1.7	1.8	5.2	-2.0	-1.4	-2.0	-0.3	-0.6	-1.5	-1.5	-0.9	-0.8	-2.3	-1.3	-0.6	-0.6
Supplements: Fish oil (including cod liver oil)	1.7	2.2	4.6	1.2	1.8	1.5	1.3	0.4	1.7	1.2	1.7	2.1	1.2	1.6	0.8	2.0
Neuroticism (2016)	1.6	2.2	8.2	-0.9	0.9	0.7	1.5	1.7	1.4	0.9	2.9	1.7	0.3	1.7	2.2	-0.3
Waist Hip Ratio (WHR)	1.6	7.3	31.9	0.2	4.0	3.1	-0.1	2.1	-0.6	0.8	4.1	3.5	0.2	1.0	1.8	5.7
Relative age of first facial hair	1.6	3.3	7.6	-1.0	-0.9	-1.6	-2.0	-1.0	-2.8	-1.6	-2.1	-1.6	-2.7	-2.3	-1.5	-1.4
Medication: Co-codamol	1.6	1.9	5.9	-2.4	-0.3	-0.8	-2.2	1.2	-1.4	-1.5	0.7	0.0	-1.5	-1.8	0.5	1.0
Hair/balding pattern: Pattern 2	1.6	2.0	4.0	0.7	1.4	1.4	0.8	0.9	1.5	1.2	1.9	2.0	1.8	1.4	1.2	1.6
Falls in the last year	1.6	2.2	8.9	-1.3	1.4	0.9	-1.2	3.0	1.1	1.0	1.6	0.9	0.9	0.4	2.6	0.5
Impedance of arm (left)	1.6	7.3	24.0	0.3	4.9	2.7	-0.1	4.0	1.1	2.6	3.9	1.4	-0.5	2.3	3.9	0.9
Emphysema/chronic bronchitis	1.6	1.8	3.7	-1.0	-1.6	-1.6	-0.5	-1.3	-1.2	-1.9	-0.6	-0.1	-1.6	-1.5	-1.3	-1.9
Body Mass Index (BMI) (2010)	1.5	2.1	4.4	0.2	-1.0	-1.3	-1.9	-1.5	-1.7	-1.3	-0.9	-1.7	-1.1	-2.1	-2.0	0.6
Hand grip strength (right)	1.5	4.2	9.8	-1.7	-2.8	-2.6	-1.2	-1.2	-1.8	-1.9	-2.4	-1.0	-1.7	-2.2	-1.6	-3.1
Fluid intelligence score	1.5	3.1	18.5	-0.3	-1.9	-1.1	4.3	-2.1	0.1	-0.1	-1.6	0.4	-0.5	1.7	-0.9	-2.3
Medication: Ibuprofen (e.g. Nurofen)	1.5	1.9	10.9	0.0	1.3	1.6	0.4	0.8	0.6	1.0	1.8	1.4	0.8	0.8	1.1	3.3
Tense / ‘highly strung’	1.5	2.5	6.0	1.5	1.6	1.2	1.9	1.0	1.5	2.4	2.1	0.2	0.7	2.5	1.4	-1.1
Deep venous thrombosis (DVT) (self-reported)	1.5	1.9	8.9	0.5	-0.8	-1.4	-3.0	-0.9	-0.4	-1.0	-0.8	-0.6	-0.4	-2.4	-1.7	-0.9
Number of treatments/medications taken	1.4	2.6	11.8	-1.0	1.4	1.1	-0.9	1.6	-0.4	0.0	2.8	2.2	0.1	-0.2	1.3	3.4
Frequency of depressed mood in last 2 weeks	1.4	2.0	7.5	-1.8	-0.7	-1.7	-0.3	0.6	-1.4	-0.9	-0.7	-2.7	-2.0	-0.6	0.3	-1.8
Medication for hormone replacement therapy	1.4	1.6	3.9	2.0	1.4	1.3	0.1	0.9	1.6	1.9	0.6	0.9	1.5	1.3	0.8	-0.3
Average weekly fortified wine intake	1.4	1.7	6.7	-0.5	1.1	1.3	0.2	1.5	0.6	0.5	2.6	1.2	0.8	0.8	1.6	2.0
Age when periods started (menarche)	1.4	3.4	8.8	-0.9	-1.2	-1.7	-2.7	-1.3	-2.5	-1.8	-0.4	-0.4	-2.6	-3.0	-1.9	-1.0
Impedance of arm (right)	1.4	6.6	22.2	-0.2	4.7	2.5	-0.6	4.0	0.6	2.3	3.6	1.6	-0.9	1.8	3.7	1.3
Father’s age at death	1.4	1.9	6.8	-0.0	-2.0	-1.3	1.9	-2.6	-0.9	-1.2	-1.3	0.2	-0.8	-0.2	-2.0	-0.7
Depression (self-reported)	1.4	1.7	4.6	-1.5	-0.8	-1.3	-1.4	0.1	-1.7	-1.3	-0.1	-2.1	-1.7	-1.5	-0.3	-1.2
Medication: Amlodipine	1.4	1.9	9.2	-1.4	1.0	1.2	-0.8	2.2	0.3	0.3	0.6	0.2	1.2	0.2	1.9	3.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.4	1.6	4.8	-2.2	-1.2	-1.5	0.5	-0.4	-1.4	-1.7	-0.6	-0.8	-2.1	-0.7	-0.2	-1.0
Medication for cholesterol	1.4	2.1	5.0	-0.8	-2.2	-1.8	0.1	-1.9	-1.1	-1.9	-1.3	-1.6	-1.2	-1.3	-1.6	-0.7
Ever smoked	1.4	2.4	10.2	-0.9	1.5	1.0	-3.2	3.1	0.1	0.6	0.5	-1.3	0.5	-0.8	2.1	-0.2
HDL Cholesterol	1.3	2.2	13.1	-0.4	-2.0	-0.5	1.5	-0.9	1.8	-0.0	-1.5	0.3	1.4	0.5	-0.3	-3.6
Hand grip strength (left)	1.3	3.3	7.0	-1.3	-2.4	-2.3	-1.4	-1.0	-1.4	-1.7	-2.4	-1.5	-1.3	-2.0	-1.4	-2.6
Hearing difficulty/problems: Yes	1.3	2.0	4.9	-2.2	-1.4	-1.4	-1.8	1.2	-0.8	-1.1	-0.9	-2.0	-0.7	-1.5	0.4	-2.0
Medication: Aspirin	1.3	1.7	9.1	0.0	0.8	0.7	1.5	0.3	0.3	0.2	2.2	1.7	0.3	1.2	0.7	3.0
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.3	1.5	4.5	-1.5	-1.3	-2.0	1.4	-0.5	-0.7	-0.9	-0.1	-0.9	-1.7	0.1	-0.0	-2.1
Alcohol drinker status: Never	1.3	1.6	3.7	0.7	1.0	1.4	1.7	0.9	1.4	1.7	1.0	1.2	1.0	1.9	1.3	0.1
Ever depressed for a whole week	1.3	1.6	5.0	2.2	0.4	1.1	1.1	-0.9	1.7	1.6	0.4	1.1	1.8	1.1	-0.5	0.5
Verbal and Numeric Reasoning (VNR)	1.2	2.8	10.5	-0.1	-2.2	-1.2	3.2	-2.2	-0.0	-0.5	-3.1	-0.7	-0.1	1.0	-1.3	-1.6
Crohns Disease (2012)	1.2	1.9	10.0	1.3	2.1	1.5	-3.2	0.8	-0.5	0.3	1.1	0.0	0.4	-1.2	-0.1	1.6
Lupus	1.2	1.8	5.3	1.0	1.9	1.4	-0.8	1.6	1.1	1.6	2.3	0.8	1.1	0.7	1.3	-0.2
Ulcerative Colitis	1.2	1.8	4.6	1.2	-0.5	-0.8	-1.6	-2.0	-1.0	-1.0	-1.2	-1.5	-0.7	-1.8	-2.2	-0.0
Blood clot in the leg (DVT)	1.2	1.5	9.1	0.4	-0.6	-1.1	-3.0	-0.6	-0.3	-0.9	-0.4	-0.4	-0.2	-2.3	-1.4	-0.4
Medication for cholesterol, blood pressure or diabetes	1.2	2.1	14.2	0.7	-1.2	-0.8	1.4	-1.0	0.8	0.3	-2.0	-1.2	0.3	0.7	-0.6	-3.8
Medication: Allopurinol	1.2	1.6	5.0	-0.5	2.0	0.9	-0.9	1.8	-0.4	0.9	2.2	1.0	-1.0	0.2	1.4	1.1
Medication: Seretide 50 evohaler	1.2	1.4	5.5	2.3	-0.4	-0.3	-1.1	-1.7	-0.2	0.2	-0.7	-0.7	0.2	-0.8	-1.9	-1.5
Illnesses of siblings: Diabetes	1.2	1.5	4.5	-0.6	-0.8	-0.8	-2.1	-0.0	-0.9	-0.8	-2.0	-1.9	-0.3	-1.7	-0.7	1.0
Smoking status: Current	1.2	1.9	11.2	-0.8	-0.5	-0.5	-3.3	0.6	-1.0	-1.0	-0.5	-1.1	-0.5	-2.4	-0.4	-1.6
Ever used hormone-replacement therapy (HRT)	1.1	1.4	4.1	-1.2	-1.1	-1.0	-2.0	0.1	-0.8	-1.2	-1.7	-1.2	-0.6	-1.8	-0.5	-0.5
Current tobacco smoking	1.1	1.8	9.5	-1.0	-0.8	-0.7	-3.1	0.3	-0.9	-1.3	-0.5	-0.7	-0.5	-2.4	-0.6	-1.7
Alcohol intake versus 10 years previously	1.1	1.6	5.1	0.8	2.2	1.1	-0.8	1.6	0.6	1.3	2.2	0.9	0.0	0.6	1.3	0.9
Birth weight of first child	1.1	1.9	7.7	0.2	-0.9	-1.5	-1.9	-0.7	-0.6	-0.5	-2.0	-0.9	-1.0	-1.6	-1.1	-2.8
Qualifications: NVQ or HND or HNC or equivalent	1.1	1.3	2.1	0.6	1.5	1.2	-0.8	1.3	1.1	1.1	1.3	1.4	1.3	0.4	1.1	1.1
High cholesterol (Self-reported)	1.1	1.9	12.0	0.8	1.8	1.3	-0.8	0.3	-0.6	0.4	1.6	1.7	-0.1	-0.1	0.1	3.5
Intelligence (Savage-Jansen 2018)	1.0	3.0	17.5	0.3	-2.0	-0.7	4.2	-2.1	1.0	0.1	-1.9	-0.3	0.7	1.9	-0.8	-1.8
Schizophrenia vs Biploar Disorder	1.0	1.4	4.7	1.2	2.0	1.4	0.7	0.7	0.5	1.1	2.2	0.0	0.2	1.3	0.9	0.2
Alzheimer’s Disease (in mother)	1.0	1.1	2.6	-0.2	0.8	0.8	1.5	1.2	1.2	0.8	0.3	0.8	0.9	1.6	1.5	1.0
Sensitivity / hurt feelings	1.0	1.7	5.4	0.4	1.6	1.3	0.1	1.7	1.1	1.0	1.0	-0.2	1.1	1.2	1.7	2.3
Severe depression (siblings)	1.0	1.1	4.7	-0.6	-1.0	-1.2	1.8	-0.7	-0.7	-0.2	-0.2	-0.8	-1.2	0.6	-0.4	-2.2
Time employed in main current job	1.0	1.1	2.6	0.4	1.1	1.3	1.1	0.9	1.1	0.8	0.3	0.6	1.6	1.4	1.2	1.2
Supplements: Vitamin C	1.0	1.1	3.0	-0.2	1.3	1.2	-0.8	1.7	0.8	0.6	1.3	0.8	1.0	0.3	1.4	1.2
Illnesses of father: Heart disease	1.0	1.3	4.1	1.8	0.2	-0.0	-1.1	-1.8	-0.6	-0.3	-1.2	-0.1	-0.0	-1.1	-2.0	1.7
Commuting to job workplace: Cycle	1.0	1.2	4.9	-1.4	-1.3	-1.3	1.0	0.1	-0.7	-0.6	-0.7	-1.5	-0.7	0.2	0.2	-2.2
Reaction Time	0.9	1.7	6.5	2.1	0.4	0.3	-2.5	-1.1	-0.9	0.2	-1.4	-0.6	0.3	-1.7	-1.8	-0.6
Mean Putamen Volume	0.9	1.0	6.0	1.0	0.0	-0.3	-2.5	0.0	0.1	0.1	-0.9	-1.2	0.1	-1.3	-0.6	-1.2
Average weekly spirits intake	0.9	1.1	5.2	-1.4	0.1	0.2	-2.3	1.2	-0.1	-0.5	1.2	1.2	0.1	-1.4	0.6	0.5
Vitamin and mineral supplements	0.9	1.2	2.5	-0.4	-1.5	-1.0	0.3	-1.4	-1.2	-0.9	-1.6	-1.1	-1.1	-0.7	-1.3	-1.2
Medication: Ramipril	0.9	1.2	3.8	-1.2	-0.9	-1.0	-1.8	-0.3	-1.1	-1.4	0.1	0.7	-0.7	-1.9	-0.8	0.2
Hair/balding pattern: Pattern 3	0.9	1.4	3.6	0.7	1.9	1.3	-0.7	1.8	0.8	1.5	1.6	0.5	0.5	0.7	1.3	-0.2
Noisy workplace	0.9	1.1	8.6	0.4	0.9	0.1	-2.9	0.6	-0.8	-0.1	0.1	-0.7	-0.6	-1.6	-0.3	-0.5
Serious illness, injury or assault of a close relative in last 2 years	0.9	1.0	6.3	-0.1	-1.0	-1.3	-0.1	-0.8	-0.6	-0.3	-0.3	-1.0	-1.0	-0.6	-0.8	-2.5
Mouth/teeth dental problems: Dentures	0.9	1.5	4.3	0.3	0.7	1.6	0.0	1.7	1.5	1.3	0.9	1.0	2.1	1.1	1.5	-0.1
Medication: Cholesterol lowering	0.9	1.5	5.2	-0.1	-0.3	-0.9	-0.5	-1.3	-1.8	-1.2	0.6	0.0	-1.7	-1.2	-1.4	2.3
Prospective memory result	0.9	1.1	6.4	-0.6	0.6	0.7	-0.3	1.4	0.3	0.7	2.5	1.4	0.4	0.3	1.3	0.0
Glaucoma (self-reported)	0.9	1.0	6.3	-2.5	-0.2	-0.1	0.2	1.8	0.2	-0.6	0.1	-0.0	-0.0	0.2	1.7	0.8
Hypothyroidism/myxoedema (self-reported)	0.9	1.8	4.1	1.3	1.3	1.5	0.1	0.8	1.6	1.2	1.7	2.0	1.7	1.1	0.9	0.7
Exposure to tobacco smoke outside home	0.9	1.2	10.0	0.1	1.1	0.5	-3.2	1.3	-0.4	0.2	-0.6	0.0	0.3	-1.4	0.3	0.4
Medication: Ibuprofen	0.9	1.0	6.6	0.1	0.8	1.1	0.4	0.3	0.2	0.6	1.6	1.0	0.4	0.5	0.5	2.6
Overall health rating	0.9	1.9	7.7	-1.1	-0.5	-1.6	-2.2	0.5	-1.2	-0.8	0.3	-0.8	-1.6	-1.7	-0.2	-2.8
Chest pain or discomfort	0.9	1.3	5.2	-2.1	0.0	-0.5	-1.5	2.3	0.2	-0.2	1.3	-0.4	-0.0	-0.5	1.7	-0.2
Had major operations	0.9	1.1	3.7	0.0	1.2	0.7	-1.8	1.9	0.5	0.3	0.1	-1.6	0.8	-0.1	1.3	0.4
Age at last live birth	0.9	1.3	2.2	0.0	-1.1	-1.3	0.2	-1.5	-1.2	-0.9	-1.2	-1.5	-1.4	-0.7	-1.4	-1.3
Illnesses of father: None of the above (group 1)	0.9	1.2	5.2	-2.3	-0.4	-0.8	1.1	1.1	-0.3	-0.4	0.9	-0.2	-1.3	0.6	1.6	-1.0
Myopia	0.9	1.3	5.1	-1.9	0.5	-0.1	0.9	2.1	0.6	0.3	0.5	0.8	-0.4	1.1	2.3	0.3
Fasting Glucose	0.8	0.9	3.6	-0.3	-0.8	-0.6	-1.0	-0.4	-0.8	-0.6	-1.5	-1.1	-0.5	-1.1	-0.8	-1.9
Rheumatoid Arthritis	0.8	1.2	2.8	0.2	-0.4	-0.7	-1.7	-0.9	-1.2	-0.9	-0.3	-1.3	-0.6	-1.6	-1.2	-1.4
Blood Red Count	0.8	7.6	14.3	1.3	2.6	3.3	1.0	2.1	3.2	2.7	2.5	3.4	3.7	2.4	2.3	3.8
Blood White Count	0.8	5.9	16.6	-0.1	4.1	2.6	-2.0	3.2	0.0	1.4	3.9	1.7	0.0	0.3	2.5	3.5
Smoking Status	0.8	2.0	13.0	-0.1	1.2	1.0	-3.6	2.3	0.1	0.4	0.9	-0.3	0.6	-1.3	1.2	-1.0
Allergy or Eczema	0.8	2.0	6.1	0.8	-0.7	-1.2	-2.3	-0.9	-0.6	-0.8	-1.7	-1.3	-0.4	-1.9	-1.7	-2.5
Cardiovascular Disease	0.8	2.5	8.7	-1.2	1.8	1.2	-1.3	1.8	-0.8	0.1	2.5	2.1	-0.5	-0.3	1.3	3.0
Eye problems/disorders: Diabetes related eye disease	0.8	0.9	3.1	0.4	-1.1	-1.2	0.9	-1.8	-0.7	-0.6	-1.0	-0.2	-0.8	-0.2	-1.5	-0.1
Relative age voice broke	0.8	1.2	2.7	-0.1	-0.4	-0.9	-1.6	-0.6	-1.2	-0.4	-1.4	-1.1	-1.2	-1.5	-1.0	-1.4
Supplements: Glucosamine	0.8	1.0	8.6	-0.6	0.4	0.4	0.7	0.1	0.1	-0.2	0.5	1.7	0.3	0.3	0.3	2.9
High blood pressure (mother)	0.8	1.2	4.5	1.6	1.8	0.9	-2.1	0.6	0.6	0.9	1.2	0.2	0.8	-0.5	-0.0	-0.7
Past tobacco smoking	0.8	1.6	6.9	0.9	-1.1	-0.7	2.0	-2.6	-0.1	-0.5	-1.1	1.1	-0.4	0.2	-2.0	0.4
Nervous feelings	0.8	1.5	5.2	-0.8	-1.3	-1.5	0.7	-0.4	-0.5	-0.3	-1.6	-2.2	-1.2	0.1	-0.1	-2.3
Seen doctor (GP) for nerves, anxiety, tension or depression	0.8	1.2	4.1	-0.6	0.6	-0.1	-1.2	2.0	0.5	0.5	-0.3	-1.5	-0.0	0.1	1.5	-2.0
Qualifications: O levels/GCSEs or equivalent	0.8	1.3	4.7	-0.6	-1.3	-0.9	0.7	-1.4	-1.1	-1.3	-2.2	-0.9	-1.2	-0.5	-1.1	0.2
Reason for reducing amount of alcohol drunk: Health precaution	0.8	0.9	1.9	-0.1	-1.3	-1.1	-0.6	-1.3	-0.5	-0.8	-0.2	1.2	-0.7	-1.1	-1.4	-1.1
Medication for pain relief, constipation, heartburn	0.8	1.4	7.3	1.4	-0.8	-0.4	-0.1	-1.1	0.3	0.2	-2.1	-1.0	0.3	-0.2	-1.2	-2.7
Mean time to correctly identify matches	0.8	1.5	5.4	1.8	0.1	0.1	-2.3	-1.3	-0.9	-0.2	-1.1	-0.5	0.1	-1.7	-1.9	-0.1
Number of full sisters	0.8	1.0	7.3	-0.2	0.7	0.8	-0.3	0.7	0.4	0.2	1.4	1.2	0.7	0.1	0.6	2.7
Friendships satisfaction	0.8	1.0	5.4	0.1	0.2	-0.4	2.3	-0.3	0.4	0.4	0.7	0.1	-0.5	1.5	0.3	-1.8
Mineral and other dietary supplements	0.8	1.0	4.2	-0.3	-1.0	-0.8	-0.9	-0.1	-0.8	-0.5	-1.4	-2.0	-0.7	-0.8	-0.4	-1.6
Medication: Aspirin	0.8	1.0	5.7	0.0	0.4	0.3	1.4	-0.0	0.1	-0.0	1.8	1.1	0.1	1.0	0.4	2.4
Medication: Gliclazide	0.8	0.9	1.8	-0.3	-0.7	-1.1	-1.2	-0.6	-1.3	-0.9	-0.7	-0.6	-0.9	-1.3	-1.0	-1.2
Hearing aid user	0.8	0.9	3.8	-1.9	-1.0	-0.9	0.4	0.0	-0.7	-1.4	0.4	0.3	-0.7	-0.5	0.1	1.6
Average weekly beer plus cider intake	0.8	1.1	2.3	0.1	1.3	1.0	0.9	1.3	0.9	1.2	1.0	-0.2	0.8	1.4	1.5	1.1
Irritability	0.8	1.3	3.5	0.6	1.4	0.7	-0.6	1.8	0.8	1.2	1.0	-1.9	0.4	0.9	1.6	-0.7
Unable to work because of sickness or disability	0.8	1.1	2.6	-0.8	0.5	-0.2	-1.6	1.5	-1.1	-0.2	0.8	-1.4	-0.7	-0.6	1.0	-1.6
Neuroticism (Nagel 2018)	0.7	1.7	3.8	1.7	1.6	0.9	0.9	0.8	1.7	1.9	1.0	-0.6	1.0	2.0	1.1	-0.5
HbA1C	0.7	0.7	6.5	-0.6	-0.9	-0.6	0.3	-0.4	-0.5	-0.4	-0.8	0.2	-0.2	-0.4	-0.3	-2.6
Primary Biliary Cirrhosis	0.7	0.9	6.6	0.1	0.6	0.6	0.9	-0.0	-0.8	0.3	1.5	0.7	-0.4	0.6	0.3	2.6
Systolic Blood Pressure	0.7	3.7	8.6	1.6	2.6	2.9	-1.9	1.6	1.6	1.8	2.2	2.1	2.0	0.3	1.1	1.9
Hypothyroidism (self reported)	0.7	1.5	6.2	0.8	1.2	1.4	-0.5	0.7	1.0	0.8	1.9	2.5	1.4	0.3	0.6	0.6
Neuroticism	0.7	1.6	3.6	0.9	1.3	0.7	1.1	1.2	1.9	1.6	1.6	0.1	0.9	1.9	1.6	-0.3
Pack years adult smoking proportion	0.7	1.0	3.5	-0.0	0.0	-0.3	-1.9	-0.8	-1.3	-1.0	-0.3	0.1	-1.1	-1.8	-1.3	0.1
Tinnitus: Yes, but not now, but have in the past	0.7	0.8	3.3	-0.7	-0.3	-0.1	-1.3	0.6	0.0	-0.7	-1.8	-1.5	0.8	-0.8	0.1	0.3
Medication: Levothyroxine sodium	0.7	1.2	3.0	1.5	0.9	1.4	-1.0	0.3	0.7	1.0	1.5	1.7	1.3	0.1	0.1	0.4
Number of incorrect matches in round	0.7	1.1	3.8	-0.4	-0.7	-1.2	-0.2	-1.1	-1.4	-1.1	0.2	-0.4	-1.9	-0.9	-1.0	-1.4
Frequency of tenseness / restlessness in last 2 weeks	0.7	1.0	6.5	0.9	0.9	0.2	-1.3	0.8	-0.1	0.8	0.2	-2.5	-0.4	0.0	0.5	-1.4
Qualifications: None of the above	0.7	1.5	4.7	0.0	1.3	1.1	-2.0	2.2	0.9	0.7	1.8	0.4	0.9	-0.1	1.6	0.3
Number of live births	0.7	1.0	2.5	-1.6	-1.2	-1.4	0.3	0.0	-0.6	-1.0	-1.1	-1.6	-0.9	-0.4	0.1	-0.8
Illnesses of mother	0.7	0.8	1.8	-1.1	-1.4	-1.1	1.3	-0.6	-0.6	-0.9	-0.5	-0.9	-1.1	0.1	-0.2	-0.9
Ever had stillbirth, spontaneous miscarriage or termination	0.7	0.7	1.6	-0.3	-1.2	-1.2	1.1	-1.3	-0.3	-0.4	-0.6	-0.8	-0.7	-0.1	-1.0	-0.7
Back pain experienced in last month	0.7	1.0	3.1	-1.2	0.2	-0.2	0.9	1.5	0.6	0.1	1.1	0.2	0.2	1.0	1.7	-1.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.7	1.6	5.7	1.8	-1.0	-0.3	2.0	-2.4	0.3	0.2	-1.5	0.4	0.5	0.7	-1.7	-0.6
Wears glasses or contact lenses	0.7	0.8	1.9	0.5	-0.8	-0.5	-0.6	-1.2	-1.3	-0.4	-0.6	-1.2	-0.9	-0.9	-1.4	-0.5
Eye problems/disorders: Glaucoma	0.7	0.8	5.0	-2.2	-0.3	-0.1	-0.4	1.1	-0.2	-1.0	-0.3	0.3	-0.1	-0.4	1.0	1.2
Crohns Disease (2017)	0.6	1.2	5.2	1.1	1.7	1.1	-1.0	0.4	0.1	0.5	1.5	1.3	0.3	-0.1	0.2	2.3
Major Depression (MDD)	0.6	0.8	2.4	1.6	1.0	0.7	0.7	-0.1	0.8	1.1	1.0	-0.2	0.8	1.2	0.1	-0.4
Breast Cancer	0.6	1.5	6.2	0.7	2.2	1.3	-2.5	1.3	-0.2	0.7	1.2	0.4	0.2	-0.9	0.4	1.3
Schizophrenia (2014)	0.6	1.4	4.3	0.0	0.9	0.9	2.1	0.9	0.8	0.7	1.3	0.9	0.5	1.9	1.3	1.5
BMI	0.6	3.4	11.2	-2.2	-3.4	-2.3	-0.9	-1.7	-1.6	-2.4	-1.1	-0.2	-0.6	-2.4	-1.8	0.1
Systolic blood pressure, automated reading	0.6	1.8	5.3	2.3	1.5	2.0	-1.5	0.1	1.2	1.4	1.1	1.0	1.7	-0.1	-0.3	1.3
Diabetes (father)	0.6	0.7	2.1	-0.7	-1.4	-0.8	-0.2	-0.9	-0.5	-0.8	-1.4	0.2	-0.3	-1.0	-1.0	-0.7
Heel bone mineral density (BMD) T-score, automated (left)	0.6	1.4	4.0	1.3	-1.1	-1.0	0.2	-1.5	-0.4	-0.1	-1.6	-1.8	-0.1	-0.2	-1.5	-2.0
Qualifications: CSEs or equivalent	0.6	0.7	1.8	-1.4	-0.1	-0.7	-0.9	0.2	-0.9	-1.0	0.3	0.8	-1.0	-1.1	-0.1	1.2
Heart attack	0.6	0.8	8.3	-0.7	-0.0	-0.0	0.6	-0.1	-0.4	-0.6	0.8	0.3	-0.1	0.0	0.1	2.9
Medication: Simvastatin	0.6	0.8	3.8	0.5	0.1	-0.3	-0.1	-1.1	-1.3	-0.5	0.8	0.5	-0.9	-0.6	-1.2	1.9
Trunk fat-free mass	0.6	3.5	9.1	-1.5	-3.0	-1.8	-2.6	-0.3	-0.8	-1.7	-2.8	-1.6	0.9	-2.6	-1.2	-1.3
Pulse wave Arterial Stiffness index	0.6	0.7	3.5	-0.7	-0.1	0.2	1.9	0.3	0.3	0.1	-0.3	0.3	0.5	1.2	0.8	1.3
Trunk predicted mass	0.6	3.4	8.6	-1.4	-2.9	-1.7	-2.6	-0.2	-0.7	-1.6	-2.8	-1.6	1.0	-2.5	-1.1	-1.4
Hair/balding pattern: Pattern 4	0.6	1.4	4.7	0.8	-0.7	-1.1	-1.1	-1.9	-0.8	-0.9	-0.6	-0.9	-1.0	-1.6	-2.2	-0.6
Pulse wave reflection index	0.6	0.7	1.8	-1.4	-1.0	-0.8	0.8	-0.6	-1.1	-1.1	-0.4	-0.6	-0.9	-0.3	-0.3	1.1
Chronic bronchitis/emphysema (mother)	0.6	0.7	1.9	-0.5	1.2	0.8	-0.5	1.3	-0.4	0.4	1.4	0.6	-0.1	0.2	1.1	0.8
High blood pressure (siblings)	0.6	0.9	2.4	-1.2	0.1	-0.4	-1.6	0.4	-1.3	-0.8	-0.8	-0.5	-0.8	-1.3	-0.1	1.3
Worry too long after embarrassment	0.6	1.0	4.7	2.2	0.9	0.5	1.1	-0.4	1.0	1.6	0.8	-0.5	0.3	1.3	-0.1	-0.5
Pulse wave peak to peak time	0.6	0.7	4.4	0.6	0.2	-0.1	-2.1	0.0	-0.2	0.1	0.3	-0.3	-0.4	-1.2	-0.6	-1.5
Qualifications: College or University degree	0.6	1.9	9.5	-1.3	-1.4	-0.9	3.1	-1.4	-1.1	-1.1	-1.8	-0.7	-1.1	0.8	-0.5	-0.3
Eye problems/disorders: None of the above	0.6	0.6	1.7	0.6	0.7	0.7	0.8	0.6	0.5	1.1	1.3	-0.3	0.2	1.1	0.8	-0.9
Pulse rate, automated reading	0.6	1.9	7.0	1.5	2.6	2.0	-2.0	1.0	-0.0	1.2	0.6	0.7	0.7	-0.3	0.2	1.7
Suffer from ‘nerves’	0.6	0.9	4.6	-0.8	-0.1	-0.9	-0.6	0.6	-0.6	-0.5	-1.1	-2.1	-0.9	-0.3	0.4	-1.4
Whole body fat-free mass	0.6	3.3	9.5	-1.7	-3.1	-1.9	-2.2	-0.4	-0.7	-1.8	-2.5	-1.3	0.7	-2.4	-1.2	-1.3
Leg fat-free mass (right)	0.6	3.0	9.8	-1.9	-3.1	-2.1	-1.5	-0.7	-0.7	-1.9	-2.2	-1.0	0.3	-2.1	-1.2	-1.2
Whole body water mass	0.6	3.5	10.2	-1.7	-3.2	-2.0	-2.2	-0.5	-0.8	-1.9	-2.7	-1.5	0.7	-2.5	-1.3	-1.3
Number of self-reported non-cancer illnesses	0.6	1.1	5.6	-1.1	0.3	0.2	-0.7	0.6	-0.5	-0.6	1.8	1.4	-0.1	-0.6	0.4	2.4
Pain type(s) experienced in last month: Hip pain	0.6	0.8	2.5	-1.0	0.4	0.3	0.3	1.4	0.5	-0.0	1.5	0.6	0.2	0.7	1.6	0.9
Medication: Bendroflumethiazide	0.6	0.9	6.7	-0.2	0.2	0.1	-2.6	0.5	-0.8	-0.4	-0.8	-0.1	-0.2	-1.6	-0.4	-0.2
Fractured/broken bones in last 5 years	0.6	0.8	4.0	-0.5	0.7	0.4	-1.6	1.0	-0.3	0.0	-0.2	-0.5	-0.1	-0.7	0.6	2.0
Medication: Omeprazole (e.g. Zanprol)	0.6	0.8	4.6	-0.4	0.4	-0.3	-2.1	0.6	-1.1	-0.3	0.5	-0.6	-0.8	-1.4	-0.1	-0.0
Heart attack/myocardial infarction (self-reported)	0.6	0.8	8.4	-0.8	-0.1	-0.0	0.5	-0.1	-0.4	-0.6	0.8	0.4	-0.0	-0.0	0.0	2.9
Heart disease (siblings)	0.6	0.8	3.5	1.4	0.5	0.9	0.0	-0.9	0.6	0.4	-0.9	0.1	0.9	0.1	-0.8	1.9
Pack years of smoking	0.6	0.8	4.6	0.3	0.5	0.2	-2.1	-0.4	-1.0	-0.5	-0.3	-0.1	-0.6	-1.6	-1.0	0.3
Alzheimer’s Disease (including proxy)	0.5	0.8	1.4	-0.1	0.7	1.1	0.8	1.2	0.8	0.7	0.7	0.6	0.8	1.1	1.2	1.1
Heel T-Score	0.5	3.8	11.4	0.4	-2.5	-2.3	1.6	-2.6	-1.0	-1.2	-1.9	-2.2	-1.1	-0.2	-2.1	-3.4
Ever had hysterectomy (womb removed)	0.5	0.6	3.9	-0.5	-0.1	-0.4	1.2	-0.4	-0.2	-0.5	0.9	0.0	-0.3	0.4	-0.0	2.0
Supplements: Zinc	0.5	0.6	2.2	-1.0	0.1	0.2	0.0	0.7	0.3	-0.2	1.1	1.5	0.5	0.0	0.7	1.1
Leg fat-free mass (left)	0.5	2.7	8.6	-2.1	-2.9	-2.1	-1.7	-0.4	-0.8	-1.9	-1.7	-0.8	0.2	-2.2	-0.9	-1.0
Trunk fat percentage	0.5	1.9	8.8	-1.4	1.0	0.4	-0.6	2.2	0.8	0.2	3.0	1.6	0.4	0.4	2.0	0.5
Maternal smoking around birth	0.5	0.7	1.4	-0.7	-0.7	-0.9	-0.7	-0.7	-0.9	-0.8	0.1	-0.0	-1.1	-1.2	-0.9	-1.1
Leg predicted mass (left)	0.5	2.8	9.0	-2.1	-3.0	-2.2	-1.6	-0.5	-0.8	-2.0	-1.7	-0.8	0.1	-2.2	-1.0	-1.0
Alcohol usually taken with meals	0.5	0.7	2.4	-0.6	-0.6	-1.0	-0.0	-0.6	-1.5	-0.9	-1.1	-0.9	-1.2	-0.6	-0.7	-0.3
Hearing difficulty/problems with background noise	0.5	0.8	3.4	-1.4	-0.3	-0.4	-0.4	1.8	0.6	0.0	-0.2	-1.3	0.4	0.2	1.5	-0.9
Financial difficulties in last 2 years	0.5	0.7	2.5	-0.8	-0.5	-1.1	-0.9	0.0	-0.8	-1.0	-0.3	-1.6	-0.8	-0.9	-0.2	-0.3
Mouth/teeth dental problems	0.5	0.7	3.8	0.8	-0.6	-0.4	1.2	-1.9	0.1	-0.5	-0.0	0.4	-0.3	0.1	-1.3	1.0
Illnesses of siblings	0.5	0.7	2.8	-0.4	-0.2	0.2	1.7	0.4	0.9	0.4	1.1	0.8	0.4	1.2	0.9	-0.9
Worrier / anxious feelings	0.5	0.9	2.1	1.0	1.2	0.4	-0.4	1.3	0.6	1.5	1.0	-0.9	0.0	0.9	1.1	-1.0
Qualifications: A levels/AS levels or equivalent	0.5	1.2	3.2	0.4	-1.0	-0.7	1.6	-1.8	-0.7	-0.8	-1.2	-1.3	-0.8	0.3	-1.3	-1.1
Breastfed as a baby	0.5	0.7	1.9	-0.2	0.7	0.8	1.1	0.6	0.5	0.8	0.6	0.3	0.7	1.1	0.9	1.4
Arm fat-free mass (right)	0.5	2.6	8.4	-1.0	-2.9	-1.4	-2.1	-0.3	0.0	-1.3	-2.4	-1.1	1.5	-2.0	-1.1	-1.5
Comparative body size at age 10	0.5	1.2	5.6	-0.7	0.1	0.3	2.4	-0.6	-0.2	-0.3	1.7	1.3	-0.2	1.0	0.1	2.0
Seen a psychiatrist for nerves, anxiety, tension or depression	0.5	0.7	1.6	-1.2	-0.2	-0.8	-0.4	0.4	-0.9	-0.9	0.2	-1.2	-1.0	-0.5	0.3	-1.3
Arm predicted mass (right)	0.5	2.3	7.1	-0.7	-2.7	-1.2	-2.0	-0.2	0.2	-1.1	-2.3	-1.2	1.8	-1.8	-1.0	-1.4
Knee pain experienced in last month	0.5	0.8	2.9	-1.7	-1.1	-0.6	-0.5	-0.1	-0.9	-1.3	-0.8	-0.1	-0.3	-1.0	-0.2	1.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.5	0.6	1.3	-0.7	-0.6	-1.0	-0.9	-0.4	-1.0	-0.7	0.3	0.0	-0.9	-1.1	-0.6	-0.5
Forced expiratory volume in 1-second (FEV1), predicted	0.5	1.0	1.9	0.3	1.1	1.4	-0.1	1.1	0.7	0.7	1.0	1.4	1.1	0.7	1.1	1.4
Handedness (chirality/laterality): Left-handed	0.5	0.6	1.8	0.7	0.3	1.0	0.5	0.4	1.3	1.0	0.1	0.5	1.4	0.9	0.5	0.2
Eye problems/disorders: Cataract	0.5	0.6	2.6	1.2	0.5	0.6	-0.6	0.2	1.6	0.6	-0.3	0.5	1.5	0.2	0.1	-0.3
Leg predicted mass (right)	0.5	2.9	9.6	-1.8	-3.1	-2.1	-1.5	-0.7	-0.7	-1.9	-2.2	-1.0	0.3	-2.1	-1.2	-1.2
Tinnitus: Yes, now most or all of the time	0.5	0.6	2.0	1.4	1.1	0.7	0.3	-0.3	0.4	1.1	0.7	-0.4	0.6	0.6	-0.3	1.1
Number of operations (self-reported)	0.5	0.8	3.5	-0.4	0.3	-0.5	-1.9	0.8	-0.6	-0.2	-0.1	-1.6	-0.5	-1.0	0.2	1.1
Ever had prostate specific antigen (PSA) test	0.5	0.6	2.0	-0.4	-0.7	-0.7	0.9	-0.4	-0.9	-0.4	-0.3	-1.4	-0.8	0.2	-0.2	-1.2
Diastolic blood pressure, automated reading	0.5	1.6	4.5	0.6	1.9	1.5	-0.9	0.8	0.3	0.6	2.1	1.8	0.5	0.0	0.5	2.1
Schizophrenia (2018)	0.4	0.9	2.6	0.5	0.7	1.1	1.1	0.3	0.8	0.5	1.1	1.3	0.8	1.0	0.7	1.6
Alzheimer’s Disease (in father)	0.4	0.4	1.2	-0.3	0.6	1.0	-0.9	0.9	-0.0	0.2	1.1	0.3	0.2	-0.2	0.5	0.8
Ulcerative Colitis (UC)	0.4	0.7	1.7	0.2	-0.5	-0.7	0.4	-1.3	-1.0	-0.9	-0.4	-1.2	-0.8	-0.4	-1.0	0.8
Prostate Cancer	0.4	0.5	1.5	-0.1	0.3	-0.1	-1.0	-0.4	-1.0	-0.8	-0.1	0.5	-0.7	-1.0	-0.6	1.2
Blood Platelet Count	0.4	4.9	17.6	0.7	4.2	2.1	-2.5	2.2	-1.0	1.0	3.2	0.6	-0.9	-0.2	1.4	3.8
Lung FVC	0.4	1.9	6.8	0.9	-1.9	-1.0	0.8	-2.6	-0.3	-0.6	-2.1	0.5	-0.2	-0.6	-2.2	-1.1
Diabetes (mother)	0.4	0.5	2.6	-0.2	0.2	0.5	-1.6	0.6	-0.5	-0.2	-0.5	-0.3	0.8	-0.9	0.0	1.3
Taking other prescription medications	0.4	0.6	2.7	-1.3	-0.1	-0.3	-0.8	0.7	-0.4	-0.6	0.5	0.8	-0.1	-0.7	0.4	1.7
Serious illness, injury or assault to yourself	0.4	0.5	1.7	-1.3	0.1	-0.4	-0.8	1.2	-0.5	-0.5	0.2	-0.3	-0.3	-0.4	0.9	0.5
High blood pressure	0.4	1.0	4.2	0.1	1.4	1.0	-2.0	1.2	-0.3	0.4	0.6	0.4	0.3	-0.7	0.5	1.8
Stomach or abdominal pain in last month	0.4	0.5	3.0	0.3	0.2	-0.3	-0.8	0.2	-0.6	0.4	-0.1	-1.0	-0.8	-0.3	-0.1	-1.7
Diverticular disease/diverticulitis (self-reported)	0.4	0.5	1.8	-1.3	-0.8	-0.8	0.9	0.3	0.1	-0.9	0.1	0.4	-0.4	0.3	0.5	-1.2
Sitting height	0.4	2.7	13.4	0.2	-0.4	1.1	-1.7	1.9	2.2	1.2	-2.4	-0.5	3.7	-0.0	1.2	-0.1
Body mass index (BMI)	0.4	1.5	5.8	-1.3	-2.4	-1.7	0.0	-1.4	-0.7	-1.8	0.2	0.4	-0.1	-1.2	-1.3	-0.1
Had menopause	0.4	0.5	1.7	0.2	0.4	0.9	-0.2	0.9	0.9	0.5	0.3	0.3	1.3	0.5	0.9	0.2
Heel bone mineral density (BMD) T-score, automated (right)	0.4	0.9	3.0	1.7	-0.4	-0.6	1.0	-1.2	0.5	0.5	-0.9	-0.7	0.4	0.7	-1.0	-1.6
Forced expiratory volume in 1-second (FEV1)	0.4	1.3	6.5	-0.6	-1.9	-0.8	0.1	-1.4	-0.6	-1.0	-2.5	0.3	-0.0	-1.0	-1.3	0.1
Medication: Lansoprazole	0.4	0.4	2.4	-0.5	0.3	0.1	-1.5	1.0	-0.4	0.2	-0.1	0.3	-0.3	-0.7	0.5	-0.6
Forced expiratory volume in 1-second (FEV1), Best measure	0.4	1.3	6.7	0.8	-1.4	-0.3	0.1	-1.9	-0.2	-0.4	-2.6	-0.1	0.4	-0.7	-1.7	-0.1
Standing height	0.4	4.0	17.8	-1.7	0.8	0.9	-3.8	4.2	0.9	0.8	-1.1	-1.1	1.7	-0.9	2.7	-0.8
Medication: Paracetamol	0.4	0.7	2.9	-1.7	0.6	0.1	-0.3	1.3	-0.5	-0.3	0.9	0.6	-0.7	-0.1	1.2	0.8
Forced vital capacity (FVC), Best measure	0.4	1.5	8.1	0.8	-1.5	-0.5	-0.4	-1.8	-0.2	-0.3	-2.8	-0.3	0.3	-1.0	-1.8	-0.8
Health satisfaction	0.4	0.6	2.2	-0.7	-0.9	-1.2	-0.5	-0.1	-0.6	-0.5	0.1	-0.6	-0.6	-0.7	-0.4	-1.5
Mouth/teeth dental problems: Loose teeth	0.4	0.5	1.4	-1.2	0.4	0.5	-0.4	1.1	0.0	-0.1	0.8	0.4	0.3	-0.1	0.9	1.0
Migraine (self-reported)	0.4	0.5	1.5	0.7	0.8	0.1	-1.2	-0.3	-0.9	0.1	0.7	-0.1	-1.0	-0.8	-0.5	-0.1
Medication: Omeprazole	0.4	0.5	2.5	-0.1	0.3	-0.3	-1.6	-0.0	-1.0	-0.5	0.7	-0.5	-0.7	-1.2	-0.5	0.3
Comparative height size at age 10	0.4	2.1	9.0	-1.0	0.5	0.6	-1.2	3.0	1.6	1.1	0.3	-0.3	1.6	0.5	2.3	-1.7
Commuting to job workplace: Car/motor vehicle	0.4	0.5	2.6	0.1	-0.6	-0.1	1.0	-0.9	-0.3	-0.3	-0.7	-0.0	0.4	0.2	-0.6	1.6
Hypertension (Self-reported)	0.4	1.1	3.8	-0.5	1.3	0.8	-1.9	1.5	-0.4	0.1	0.9	0.3	0.1	-0.7	0.8	1.8
Smoking status: Previous	0.4	0.7	2.8	-0.4	0.7	0.5	-0.3	1.7	0.5	0.5	1.0	-0.4	0.6	0.6	1.5	-0.2
Average weekly red wine intake	0.4	0.6	1.7	-1.2	-1.3	-0.8	0.4	-0.3	-0.9	-0.7	-1.1	-0.3	-0.6	-0.4	-0.4	-1.0
Mood swings	0.4	0.7	2.0	-0.3	1.1	-0.1	-1.2	1.4	0.2	0.2	1.0	-1.3	-0.4	-0.1	1.0	0.6
Mouth/teeth dental problems: Mouth ulcers	0.4	0.7	2.1	0.5	0.8	0.3	-0.6	1.1	0.5	1.1	-0.7	-1.1	0.4	0.4	0.7	-1.5
Breast cancer (self-reported)	0.4	0.5	2.6	-1.6	-0.5	-0.7	0.1	0.3	-0.5	-1.2	0.8	0.6	-0.8	-0.4	0.3	-0.3
Osteoporosis (self-reported)	0.4	0.4	1.7	-0.6	0.8	0.4	-0.2	1.3	0.7	0.6	0.3	-0.2	0.5	0.4	1.2	0.1
Average weekly champagne plus white wine intake	0.4	0.5	3.1	-0.2	-1.0	-0.6	0.3	-0.5	-0.4	0.1	-1.8	0.0	-0.0	-0.1	-0.4	-1.2
Medication: Atorvastatin	0.4	0.5	2.2	-0.1	1.2	0.4	-0.3	0.5	-0.3	-0.1	1.5	0.3	-0.6	0.0	0.4	1.4
Basal metabolic rate	0.4	2.4	7.3	-1.8	-2.7	-1.6	-2.1	0.0	-0.5	-1.6	-1.8	-1.0	0.8	-2.1	-0.7	-1.0
Arm fat-free mass (left)	0.4	2.1	7.3	-1.5	-2.7	-1.4	-1.7	0.0	-0.2	-1.4	-2.0	-0.9	1.3	-1.8	-0.7	-1.0
Vascular/heart problems diagnosed by doctor	0.4	1.1	6.3	0.1	-1.3	-1.0	1.4	-1.2	0.3	-0.4	-1.0	-0.4	-0.3	0.4	-0.6	-2.5
Cholesterol lowering medication	0.4	0.5	2.6	-0.1	0.7	0.0	-0.5	-0.0	-1.3	-0.3	0.6	0.3	-1.0	-0.4	-0.3	1.6
Basal cell carcinoma (self-reported)	0.4	0.4	1.4	-0.2	-0.2	-0.9	-1.1	-0.1	0.0	-0.7	0.0	0.2	-0.6	-0.9	-0.5	-1.2
Arm predicted mass (left)	0.4	2.2	7.7	-1.4	-2.8	-1.4	-1.9	-0.1	-0.1	-1.4	-2.0	-0.8	1.4	-1.9	-0.8	-1.1
Worry (Nagel 2018)	0.3	0.7	3.5	0.6	0.4	-0.2	0.8	0.4	0.5	1.0	0.4	-0.6	-0.3	1.1	0.7	-1.9
Blood Eosinophil Count	0.3	2.1	6.0	-2.3	-2.5	-1.7	-0.4	-0.3	-1.0	-1.7	-1.2	-0.8	-0.9	-1.3	-0.4	-2.0
Height	0.3	6.2	27.2	-1.3	1.1	0.8	-3.6	5.2	2.3	1.6	-1.1	-1.7	2.5	-0.1	3.6	-2.4
Lung FEV1/FVC ratio	0.3	1.5	3.2	-0.5	-1.7	-0.3	-0.2	-1.8	-0.9	-1.5	-1.7	0.5	-0.0	-1.4	-1.7	1.4
Angina	0.3	0.4	1.5	-0.4	0.3	0.2	1.0	0.7	0.4	0.3	1.2	0.6	0.1	0.9	0.8	0.3
Townsend deprivation index at recruitment	0.3	0.4	3.2	-0.3	0.3	-0.1	-1.8	0.6	-0.1	-0.1	0.6	-0.2	-0.1	-1.0	0.1	0.4
Bilateral oophorectomy (both ovaries removed)	0.3	0.3	1.8	-0.2	0.3	-0.1	0.1	0.4	-0.3	-0.4	1.2	-0.1	-0.4	0.2	0.5	1.3
Hayfever, allergic rhinitis or eczema	0.3	0.8	1.6	0.1	-0.9	-1.1	-0.8	-0.8	-0.6	-0.8	-0.9	-0.6	-0.6	-1.0	-1.1	-1.3
Chronic bronchitis/emphysema (father)	0.3	0.4	1.6	1.1	0.3	-0.2	-0.8	-0.2	-0.2	0.2	-0.4	-0.7	0.2	-0.2	-0.5	-1.3
Trunk fat mass	0.3	1.1	3.3	-1.7	-0.1	-0.3	-1.3	1.8	0.4	-0.4	1.8	0.9	0.4	-0.5	1.4	-0.1
Had other major operations	0.3	0.3	1.1	-1.1	-0.7	-0.8	-0.7	0.3	0.1	-0.4	-0.9	-0.5	0.0	-0.7	0.0	-0.0
Pain all over the body in last month	0.3	0.3	0.9	-0.4	0.1	0.0	-0.6	-0.1	-1.0	-0.6	0.7	0.4	-0.8	-0.6	-0.2	0.7
Diabetes (self-reported)	0.3	0.4	1.3	1.1	-0.2	-0.0	0.9	-0.5	0.8	0.2	-0.4	0.5	1.1	0.7	-0.3	-0.5
Arm fat percentage (right)	0.3	1.1	4.0	-1.8	-0.6	-1.1	-0.2	0.1	-0.9	-1.3	2.0	1.1	-1.1	-0.7	0.1	0.3
Hip circumference	0.3	1.5	4.0	-2.0	-1.8	-1.2	-1.3	1.3	0.4	-0.6	-0.4	-1.0	0.6	-0.8	0.9	-1.8
Happiness	0.3	0.3	0.8	0.8	0.2	0.3	0.8	-0.3	0.7	0.9	-0.5	0.3	0.4	0.7	-0.1	-0.6
Lung cancer (father)	0.3	0.3	2.8	0.5	-0.5	-0.4	0.3	-0.4	0.1	0.3	-0.0	0.2	-0.1	0.1	-0.2	-1.7
Peak expiratory flow (PEF)	0.3	0.7	2.2	-0.5	-1.0	-0.7	-1.1	-0.6	-0.8	-0.8	-1.5	-0.5	-0.2	-1.2	-0.9	-0.0
Body fat percentage	0.3	1.1	6.3	-1.4	0.3	-0.1	-0.4	1.3	0.3	-0.3	2.5	1.3	0.0	-0.1	1.2	0.2
Family relationship satisfaction	0.3	0.3	2.3	-0.3	-0.1	-0.1	1.5	0.0	0.4	0.3	0.1	-0.6	0.1	0.9	0.4	-0.4
Long-standing illness, disability or infirmity	0.3	0.5	1.5	-0.1	-0.3	-0.8	-1.2	-0.1	-0.7	-0.6	0.5	-0.2	-0.7	-1.0	-0.4	-1.1
Ever had bowel cancer screening	0.3	0.4	2.2	-1.5	-0.1	-0.2	0.7	0.8	-0.1	-0.2	0.5	0.5	-0.5	0.3	1.0	0.0
Diabetes diagnosed by doctor	0.3	0.5	1.5	1.0	-0.1	0.2	1.0	-0.4	0.9	0.3	-0.4	0.8	1.2	0.9	-0.1	0.0
Qualifications: nursing, teaching	0.3	0.5	1.7	0.0	0.1	-0.1	0.8	-0.6	-1.3	-0.5	0.1	-1.0	-1.0	0.2	-0.4	1.2
Commuting to job workplace: Walk	0.3	0.3	0.9	0.5	0.5	0.5	-0.4	0.6	0.7	0.7	-0.5	-0.3	0.2	0.3	0.5	-1.0
Mother’s age at death	0.3	0.4	2.3	0.5	-0.1	0.3	1.5	-0.7	0.7	0.3	0.1	0.4	0.4	0.9	-0.3	0.0
Medication: Paracetamol	0.3	0.5	2.0	-1.4	0.4	0.2	-0.0	1.1	-0.2	-0.3	0.7	0.8	-0.1	0.0	1.0	0.8
Medication: Lisinopril	0.3	0.4	1.8	-0.9	0.1	0.3	-0.4	0.8	-0.6	-0.1	0.4	0.9	0.0	-0.1	0.7	1.4
Risk taking	0.3	0.4	1.2	1.1	0.4	0.3	0.0	-1.0	-0.4	-0.1	0.3	0.8	-0.2	-0.2	-1.1	0.5
Age started oral contraceptive pill	0.3	0.4	1.5	0.7	-0.5	-0.2	-0.4	-1.1	0.2	-0.2	-1.1	0.4	0.2	-0.6	-1.2	0.2
Supplements: Calcium	0.3	0.3	2.1	-0.1	0.6	0.3	0.2	0.3	0.3	-0.2	0.8	-0.1	0.3	0.3	0.4	1.4
Alcohol drinker status: Previous	0.3	0.4	1.8	-0.2	0.6	0.4	-0.5	1.3	0.4	0.4	0.2	-0.1	0.5	0.3	1.1	-0.6
Bipolar Disorder or Schizophrenia	0.2	0.4	1.3	0.5	0.4	0.6	1.1	-0.2	0.6	0.3	0.7	0.8	0.5	0.9	0.3	0.8
Depressed Affect (Nagel 2018)	0.2	0.3	1.0	0.9	1.0	0.3	0.3	0.1	0.9	0.6	0.5	-0.3	0.3	0.6	0.3	0.5
Irritable Bowel Disease (IBD)	0.2	0.5	3.7	0.9	0.8	0.2	-0.1	-0.7	-0.3	-0.1	0.6	0.4	-0.3	-0.2	-0.6	1.9
Type 2 Diabetes (T2D) (2018)	0.2	0.3	0.8	0.3	-0.9	-0.2	-0.5	-0.5	0.1	-0.6	-0.8	0.6	0.8	-0.5	-0.7	-0.5
Chronotype (morning person)	0.2	0.4	2.7	1.6	-0.1	0.1	0.4	-1.2	0.5	0.4	0.3	-0.3	0.4	0.2	-1.0	0.1
Other serious medical condition/disability diagnosed by doctor	0.2	0.3	0.9	-0.1	-0.1	-0.3	-0.2	-0.6	-0.7	-0.4	0.7	0.8	-0.5	-0.5	-0.6	1.0
Medication: Metformin	0.2	0.3	1.2	1.1	-0.0	-0.1	0.3	-0.2	0.9	0.2	-0.8	0.1	1.0	0.5	-0.1	-0.4
Fed-up feelings	0.2	0.3	2.3	0.4	0.4	-0.1	-0.7	0.1	-0.2	0.1	0.5	-1.5	-0.5	-0.2	-0.0	-0.0
Multivitamins +/- minerals	0.2	0.2	0.6	-0.5	-0.2	-0.7	0.0	-0.3	-0.5	-0.8	0.6	-0.4	-0.5	-0.4	-0.2	0.7
Waist circumference	0.2	0.7	2.5	-1.6	-0.3	-0.2	-0.9	1.3	-0.3	-0.7	1.3	0.2	0.3	-0.5	0.9	1.0
Forced vital capacity (FVC)	0.2	0.9	5.8	-0.5	-1.5	-0.8	-0.3	-0.9	-0.3	-0.6	-2.4	-0.0	0.0	-0.9	-0.9	-0.3
Hayfever/allergic rhinitis (self-reported)	0.2	0.2	1.1	0.1	-0.0	-0.1	1.0	-0.1	0.4	0.0	0.7	0.7	0.1	0.7	0.2	-0.3
Neuroticism score	0.2	0.5	1.3	0.2	0.6	-0.2	0.4	0.7	0.6	0.8	0.7	-1.1	-0.3	0.9	0.9	-0.6
Weight	0.2	1.2	3.8	-1.9	-1.8	-1.1	-1.5	0.7	-0.1	-1.2	-0.1	-0.0	0.8	-1.4	0.2	-0.5
Pulse rate	0.2	0.3	1.0	0.8	0.8	0.6	0.1	-0.3	0.1	0.2	-0.6	0.1	0.2	0.2	-0.3	1.0
Arm fat mass (right)	0.2	0.9	3.5	-1.9	-1.3	-1.1	-0.5	0.3	-0.5	-1.2	1.2	0.7	-0.1	-0.9	0.2	0.2
Length of working week for main job	0.2	0.3	1.1	0.4	-0.0	-0.0	-0.9	-0.4	-0.2	-0.5	0.1	0.2	0.1	-0.7	-0.5	1.0
Exposure to tobacco smoke at home	0.2	0.3	0.7	0.3	0.9	0.6	-0.6	0.8	-0.1	0.3	-0.5	-0.5	0.2	0.2	0.7	0.5
Ever highly irritable/argumentative for 2 days	0.2	0.2	1.4	-0.3	-0.4	-0.6	0.4	-0.2	-0.1	0.1	-0.4	-0.6	-0.4	0.1	-0.1	-1.2
Headache pain in last month	0.2	0.3	1.1	-0.4	0.5	-0.0	-0.3	0.1	-0.9	0.3	0.6	0.3	-1.1	-0.3	0.1	0.7
Leg fat percentage (right)	0.2	0.8	5.5	-0.7	0.2	0.2	-0.3	0.9	0.6	-0.0	2.3	1.2	0.7	0.1	0.9	0.3
Age at first live birth	0.2	0.4	1.3	1.1	-0.0	0.0	1.0	-0.9	-0.1	0.4	-0.3	-0.4	0.0	0.6	-0.6	-0.8
Shortness of breath walking on level ground	0.2	0.2	1.6	0.2	-0.8	-0.5	-0.0	-0.5	0.4	0.1	0.2	-0.1	-0.1	-0.2	-0.5	-1.3
Angina (self-reported)	0.2	0.2	1.1	-0.5	0.1	0.0	0.8	0.4	0.1	0.1	1.1	0.3	-0.1	0.6	0.5	-0.1
Heart disease (mother)	0.2	0.2	0.9	-0.0	-0.5	-0.8	0.3	-0.4	-0.4	-0.1	-0.1	-0.3	-0.6	-0.0	-0.4	-0.9
Whole body fat mass	0.2	1.0	4.2	-2.0	-0.8	-0.9	-1.1	1.1	-0.2	-1.0	1.4	0.7	-0.0	-0.9	0.7	-0.3
Leg fat mass (right)	0.2	0.7	2.4	-1.6	-1.1	-0.6	-0.7	0.5	0.0	-0.9	1.3	0.9	0.5	-0.7	0.4	0.1
Illness, injury, bereavement, stress in last 2 years	0.2	0.2	0.8	0.0	0.3	0.9	0.5	0.0	0.4	0.3	-0.2	0.7	0.7	0.3	0.1	0.5
Arm fat percentage (left)	0.2	0.9	4.0	-1.6	-0.6	-1.1	-0.2	0.0	-0.7	-1.2	2.0	0.9	-1.0	-0.6	0.1	0.0
Loneliness, isolation	0.2	0.3	1.2	-0.3	0.3	0.3	0.9	0.2	0.7	-0.0	-0.0	0.5	0.3	0.6	0.5	1.1
Osteoarthritis (self-reported)	0.2	0.3	0.9	0.3	-0.5	-0.4	0.7	-0.9	0.1	-0.1	0.3	0.7	0.0	0.1	-0.7	0.6
Arm fat mass (left)	0.2	1.0	3.8	-1.9	-1.4	-1.2	-0.7	0.3	-0.6	-1.4	1.0	0.6	-0.2	-1.1	0.1	-0.2
Miserableness	0.2	0.4	1.4	0.3	0.8	0.5	0.5	0.2	0.7	0.7	0.9	0.1	0.2	0.6	0.4	1.2
Medication: Blood pressure	0.2	0.4	1.4	-1.1	0.7	0.2	-0.9	1.2	-0.5	-0.1	0.1	0.4	-0.3	-0.4	0.7	0.2
Leg fat percentage (left)	0.2	0.8	5.0	-0.4	0.3	0.4	-0.1	0.9	0.9	0.2	2.2	1.3	1.0	0.3	0.9	0.1
Pain experienced in last month	0.2	0.3	1.0	0.6	0.3	0.5	0.8	-0.1	0.5	0.4	0.3	0.7	0.5	0.7	0.2	1.0
Leg fat mass (left)	0.2	0.7	2.3	-1.5	-1.1	-0.6	-0.6	0.5	0.1	-0.9	1.1	0.9	0.6	-0.7	0.4	-0.1
Bipolar Disorder (2018)	0.1	0.1	0.5	-0.0	-0.3	-0.5	0.5	-0.7	-0.2	-0.3	-0.1	-0.3	-0.3	0.0	-0.3	-0.6
Ovarian Cancer	0.1	0.1	0.4	-0.3	-0.1	-0.2	-0.6	0.1	-0.3	0.1	0.3	-0.1	-0.3	-0.5	-0.1	-0.5
Age at First Birth	0.1	0.2	0.5	0.0	-0.6	-0.4	0.7	-0.6	-0.2	-0.1	-0.7	-0.6	-0.3	0.2	-0.3	0.1
Hair Pigment	0.1	2.0	6.0	-0.2	2.4	1.1	-1.8	2.2	0.2	1.0	2.5	0.6	-0.5	0.0	1.7	-0.2
Tanning	0.1	0.7	1.6	-0.6	-1.3	0.0	1.3	0.2	1.0	0.1	-1.1	0.7	1.1	0.8	0.5	-0.6
Financial situation satisfaction	0.1	0.1	0.4	0.2	0.2	-0.1	-0.6	0.5	0.4	0.3	-0.2	-0.4	0.4	-0.0	0.2	-0.7
Illnesses of father: High blood pressure	0.1	0.1	0.3	-0.2	-0.0	0.0	-0.6	0.0	-0.4	-0.3	-0.1	0.5	-0.1	-0.5	-0.1	0.4
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Coronary Artery Disease (CAD)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Type 2 Diabetes (T2D) (2012)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0

Hub : Genes

POM121B

Models

Trait associations