TWAS hub - POP7

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	TCGA	Bladder Urothelial Carcinoma	0.0420	0.0260	0.00052	0.029	0.029	0.025	NA	0.025	0.00160	0.00160	3.0e-03	NA	0.00310
2	TCGA	Head and Neck Squamous Cell Carcinoma	0.0345	0.0246	0.00260	0.002	0.018	0.020	NA	0.016	0.18000	0.00340	2.3e-03	NA	0.00520
3	TCGA	Prostate Adenocarcinoma	0.1084	0.0724	0.00150	0.031	0.027	0.041	NA	0.026	0.00028	0.00074	3.9e-05	NA	0.00082

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
Blood Red Count	66.5	642.3	1017.6	31.9	4.6	29.8
Pulse rate, automated reading	11.0	35.6	64.6	-5.8	-8.0	2.9
Pulse rate	7.7	12.9	26.3	-2.2	-5.1	2.8
Blood Platelet Count	7.2	83.3	151.3	-12.3	-2.8	-9.5
Schizophrenia (2014)	4.9	10.8	19.3	0.1	-4.4	3.6
Stomach or abdominal pain in last month	4.5	5.5	8.9	3.0	2.7	0.7
Schizophrenia (2018)	4.2	8.7	17.0	-0.2	-4.1	3.0
Bipolar Disorder or Schizophrenia	3.5	8.5	14.7	-0.1	-3.8	3.3
Crohns Disease (2012)	3.1	5.0	10.7	1.3	-1.6	3.3
Age at First Birth	3.0	4.3	6.7	-2.2	1.1	-2.6
HbA1C	3.0	3.3	6.0	1.8	0.8	2.4
Schizophrenia vs Biploar Disorder	2.9	3.9	7.6	1.4	-1.5	2.8
Hypothyroidism/myxoedema (self-reported)	2.7	5.3	15.3	0.7	3.9	-0.1
Cholesterol lowering medication	2.6	3.8	5.8	-2.4	-2.4	0.3
Hypothyroidism (self reported)	2.5	5.8	16.5	0.5	4.1	-0.9
Had other major operations	2.5	3.1	5.7	1.6	2.4	0.9
Pulse wave peak to peak time	2.5	2.9	5.3	-1.8	0.4	-2.3
Number of operations (self-reported)	2.5	3.7	5.2	1.5	1.9	2.3
Average weekly champagne plus white wine intake	2.3	3.2	5.2	2.1	2.3	-0.2
Supplements: Zinc	2.2	2.4	3.7	1.9	1.2	1.4
Qualifications: O levels/GCSEs or equivalent	2.2	3.4	6.1	0.2	2.0	-2.5
Forced expiratory volume in 1-second (FEV1), predicted	2.2	4.5	10.5	-1.6	0.7	-3.2
Medication: Omeprazole	2.1	2.5	5.6	1.4	2.4	-0.1
Supplements: Fish oil (including cod liver oil)	2.1	2.7	6.0	-2.5	-0.1	-1.5
Lung cancer (father)	2.0	2.3	4.4	-2.1	-1.5	0.5
Pulse wave Arterial Stiffness index	2.0	2.4	3.8	1.8	-0.4	2.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	2.0	2.3	4.6	-1.5	-0.4	-2.1
Handedness (chirality/laterality): Left-handed	2.0	2.4	3.4	-1.8	-1.6	-1.2
Type 2 Diabetes (T2D) (2018)	1.9	3.5	9.1	1.1	3.0	0.4
Prospective memory result	1.9	2.4	5.8	-1.0	-2.4	0.6
Ever had stillbirth, spontaneous miscarriage or termination	1.9	2.0	3.9	1.2	2.0	0.9
Reason for reducing amount of alcohol drunk: Health precaution	1.8	2.1	4.7	2.2	0.7	1.1
Fed-up feelings	1.6	3.0	3.9	-1.5	-2.0	1.6
Multivitamins +/- minerals	1.6	2.0	5.1	-0.7	0.7	-2.2
Age at first live birth	1.6	2.8	4.0	0.8	2.0	-1.9
Smoking status: Current	1.6	2.6	6.7	-0.5	-2.6	0.9
Fractured/broken bones in last 5 years	1.6	2.0	5.7	-0.6	-2.4	0.3
Other serious medical condition/disability diagnosed by doctor	1.5	1.9	4.5	-2.1	0.2	-1.1
Alcohol usually taken with meals	1.5	2.4	5.1	2.3	1.3	0.7
Blood White Count	1.4	10.4	27.0	1.8	-1.0	5.2
Angina	1.4	1.9	4.5	1.0	2.1	-0.4
Medication: Levothyroxine sodium	1.4	2.4	5.9	-0.6	2.4	-1.0
Hair/balding pattern: Pattern 3	1.4	2.1	4.3	1.3	2.1	0.3
Depression (self-reported)	1.4	1.7	4.3	-0.0	-2.1	0.9
Seen a psychiatrist for nerves, anxiety, tension or depression	1.4	1.8	4.0	-1.0	-2.0	-0.7
Wheeze or whistling in the chest in last year	1.4	2.4	5.8	1.2	-0.1	2.4
Medication for cholesterol	1.4	2.1	4.5	1.2	2.1	-0.5
Age started oral contraceptive pill	1.4	1.8	2.8	-1.5	-0.5	-1.7
Ulcerative Colitis (UC)	1.3	2.3	6.2	-2.5	-0.4	0.8
Reaction Time	1.3	2.4	6.6	-0.4	-0.7	2.6
Breast Cancer	1.3	3.2	5.2	2.3	1.5	1.4
Had menopause	1.3	1.6	3.0	-1.7	-1.4	0.1
Serious illness, injury or assault of a close relative in last 2 years	1.3	1.5	2.7	1.6	0.9	1.0
Blood clot in the leg (DVT)	1.3	1.7	3.9	-1.0	2.0	-0.1
Mean time to correctly identify matches	1.3	2.5	5.7	-1.0	-1.0	2.4
Medication: Omeprazole (e.g. Zanprol)	1.3	1.6	3.7	1.1	1.9	-0.2
Deep venous thrombosis (DVT) (self-reported)	1.3	1.7	4.5	-0.8	2.1	0.2
Alcohol drinker status: Previous	1.3	1.5	2.5	-1.6	-0.2	-1.4
Medication: Co-codamol	1.2	1.4	3.0	0.8	0.6	1.7
Serious illness, injury or assault to yourself	1.2	1.4	3.3	0.8	0.6	1.8
Supplements: Glucosamine	1.2	1.6	4.7	0.3	2.2	-0.1
Glaucoma (self-reported)	1.2	1.5	3.4	0.9	-0.3	1.9
Angina (self-reported)	1.2	1.6	3.8	0.9	1.9	-0.5
Chest pain or discomfort	1.2	1.8	3.1	1.3	0.8	1.8
Friendships satisfaction	1.2	1.5	3.0	-0.4	-1.7	1.2
Intelligence (Savage-Jansen 2018)	1.1	3.3	8.6	0.1	1.1	-2.9
Irritable Bowel Disease (IBD)	1.1	2.5	3.1	-1.7	-1.4	1.6
Mean Putamen Volume	1.1	1.3	2.6	1.6	-0.3	1.1
Rheumatoid Arthritis	1.1	1.5	2.8	-1.7	0.4	-1.2
BMI	1.1	6.2	12.0	2.3	1.0	3.5
Ever had hysterectomy (womb removed)	1.1	1.3	1.6	-1.0	1.3	1.1
Leg fat-free mass (left)	1.1	5.8	12.3	2.2	3.5	0.6
Frequency of unenthusiasm / disinterest in last 2 weeks	1.1	1.5	2.7	-1.6	-1.2	0.7
Leg predicted mass (left)	1.1	5.8	12.1	2.2	3.5	0.7
Allergy	1.1	2.4	3.1	-1.8	-1.7	-1.1
Fluid intelligence score	1.1	2.2	3.5	-1.3	-1.2	-1.9
Time employed in main current job	1.1	1.3	2.6	0.2	-1.1	1.6
Qualifications: A levels/AS levels or equivalent	1.1	2.5	4.4	0.4	1.7	-2.1
Exposure to tobacco smoke at home	1.1	1.2	3.0	0.8	1.7	-0.0
High blood pressure (siblings)	1.1	1.6	3.8	-1.9	0.1	-1.0
Financial situation satisfaction	1.1	1.3	2.7	-1.6	-1.0	-0.6
Medication: Atorvastatin	1.1	1.4	1.7	-1.3	-1.1	-1.1
Current tobacco smoking	1.0	1.7	4.0	-0.2	-2.0	1.0
Average weekly fortified wine intake	1.0	1.2	2.2	1.5	1.0	0.6
Relative age voice broke	1.0	1.5	3.7	-1.9	-0.1	-0.9
Heart attack	1.0	1.3	2.9	1.0	1.7	-0.0
Falls in the last year	1.0	1.4	2.1	-1.1	-0.9	1.4
Pulse wave reflection index	1.0	1.2	1.9	1.4	1.0	0.8
Overall health rating	1.0	2.1	2.3	-1.5	-1.5	1.3
Eye problems/disorders: Cataract	1.0	1.1	3.1	0.4	1.8	-0.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.0	1.1	2.0	-1.1	-1.4	0.5
Medication: Blood pressure	1.0	2.0	3.1	0.0	-1.7	1.8
Medication: Paracetamol	1.0	1.6	3.0	1.7	-0.4	1.3
Medication: Lisinopril	1.0	1.3	1.7	1.3	1.1	1.0
Leg fat percentage (left)	1.0	3.5	6.4	-0.7	-1.9	2.5
Diastolic blood pressure, automated reading	1.0	3.2	8.2	0.3	-2.9	1.1
Heart attack/myocardial infarction (self-reported)	1.0	1.3	3.0	0.9	1.7	-0.2
Depression (Nagel 2018)	0.9	1.3	3.3	-0.5	-0.7	1.8
Alzheimer’s Disease (in mother)	0.9	1.0	1.8	0.7	1.0	-1.3
Prostate Cancer	0.9	1.2	3.3	-0.3	-1.8	-0.5
Ulcerative Colitis	0.9	1.3	3.1	-0.9	-0.1	1.7
Smoking Status	0.9	2.2	5.0	-1.2	-2.2	0.5
Chronic bronchitis/emphysema (father)	0.9	1.0	1.7	-0.5	-1.1	1.3
Impedance of leg (left)	0.9	4.4	11.2	-1.3	-3.3	-0.5
Pain all over the body in last month	0.9	0.9	2.4	-0.3	-0.6	1.5
Diabetes (self-reported)	0.9	1.4	4.1	0.1	2.0	-0.3
Breastfed as a baby	0.9	1.1	2.3	1.5	1.0	0.3
Medication: Ibuprofen	0.9	1.0	1.9	1.1	1.4	0.1
Qualifications: NVQ or HND or HNC or equivalent	0.9	1.1	1.4	-1.2	-1.1	-0.8
Leg fat-free mass (right)	0.9	4.9	11.8	1.6	3.4	0.3
Average weekly red wine intake	0.9	1.3	3.0	-0.9	0.1	-1.7
Diabetes diagnosed by doctor	0.9	1.5	4.4	0.1	2.1	-0.2
Leg predicted mass (right)	0.9	5.0	12.0	1.7	3.5	0.3
Miserableness	0.9	1.6	2.8	-1.3	-1.7	0.3
Medication: Bendroflumethiazide	0.9	1.4	3.0	0.3	-1.7	1.0
Crohns Disease (2017)	0.8	1.7	3.5	-0.4	-1.9	1.3
Blood Eosinophil Count	0.8	5.9	13.8	-0.0	-2.0	3.7
Systolic blood pressure, automated reading	0.8	2.5	3.7	-1.7	-0.9	-1.9
Hayfever, allergic rhinitis or eczema	0.8	1.8	3.4	1.8	0.7	1.2
Sitting height	0.8	5.7	10.7	2.3	3.3	-1.1
Frequency of tenseness / restlessness in last 2 weeks	0.8	1.3	3.1	0.4	-0.7	1.8
Medication: Simvastatin	0.8	1.2	3.4	-1.8	-0.5	0.1
Forced expiratory volume in 1-second (FEV1), Best measure	0.8	2.7	5.5	-0.6	1.4	-2.4
Leg fat percentage (right)	0.8	3.0	6.6	-0.1	-1.6	2.6
Osteoporosis (self-reported)	0.8	1.0	1.6	-1.3	-0.8	-1.0
Ever had prostate specific antigen (PSA) test	0.8	1.0	2.0	-0.3	-1.4	0.9
Major Depression (MDD)	0.7	0.8	1.8	-0.6	-0.6	1.3
Heel T-Score	0.7	5.9	7.8	2.4	2.0	2.8
Frequency of depressed mood in last 2 weeks	0.7	0.9	2.0	-0.6	-0.6	1.4
Vitamin and mineral supplements	0.7	1.0	2.6	0.5	-0.0	1.6
Maternal smoking around birth	0.7	1.0	1.1	0.9	1.1	1.1
Illnesses of siblings	0.7	1.0	2.8	1.7	0.1	0.6
Peak expiratory flow (PEF)	0.7	1.7	3.4	0.4	1.8	-1.2
Medication: Paracetamol	0.7	1.2	2.5	1.6	-0.1	1.0
Chronic bronchitis/emphysema (mother)	0.7	0.8	1.7	0.3	-1.3	0.7
Qualifications: College or University degree	0.7	2.2	3.3	1.8	1.8	-0.1
Migraine (self-reported)	0.7	0.9	1.8	0.4	0.8	1.4
Number of full sisters	0.7	0.8	2.3	0.2	1.5	-0.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.7	0.8	1.3	-0.5	1.0	-1.1
Hearing aid user	0.7	0.8	1.9	-0.4	-0.6	1.4
Risk taking	0.7	1.0	2.1	0.7	-0.6	1.5
Commuting to job workplace: Cycle	0.7	0.8	1.5	-1.2	-0.4	-0.9
Supplements: Calcium	0.7	0.8	1.5	-0.9	0.1	-1.2
Bipolar Disorder (2018)	0.6	1.0	2.1	0.1	-0.9	1.4
Waist Hip Ratio (WHR)	0.6	2.6	5.2	-0.2	1.6	-2.3
Townsend deprivation index at recruitment	0.6	0.9	1.5	1.0	0.1	1.2
Qualifications: CSEs or equivalent	0.6	0.8	1.2	-1.1	-0.4	-1.0
Number of incorrect matches in round	0.6	1.1	2.3	-0.5	-0.7	1.5
Forced expiratory volume in 1-second (FEV1)	0.6	2.0	3.5	-0.5	1.4	-1.9
Medication: Lansoprazole	0.6	0.6	1.8	-0.3	-0.1	1.4
Illnesses of mother	0.6	0.7	1.7	1.3	0.6	0.4
Length of working week for main job	0.6	0.7	0.8	-0.9	0.7	-0.9
Ever highly irritable/argumentative for 2 days	0.6	0.7	1.2	-0.8	-0.4	1.1
Medication: Amlodipine	0.6	0.9	1.8	-0.8	-1.4	-0.4
Forced vital capacity (FVC), Best measure	0.6	2.4	5.8	-0.7	0.9	-2.4
Body fat percentage	0.6	2.3	6.5	0.5	-0.2	2.6
Number of full brothers	0.6	0.8	1.6	-0.8	0.2	-1.3
Medication for pain relief, constipation, heartburn	0.6	1.0	1.4	-1.0	-1.2	0.7
Neck or shoulder pain in last month	0.6	0.9	2.1	-0.7	-0.2	1.5
Medication: Seretide 50 evohaler	0.6	0.7	1.7	0.5	-0.2	1.3
Had major operations	0.6	0.6	1.6	0.6	0.0	1.2
Age at last live birth	0.6	0.9	2.3	-0.6	-0.3	-1.5
Smoking status: Previous	0.6	1.0	1.9	0.2	1.4	-1.0
Ever had bowel cancer screening	0.6	0.7	1.2	-1.1	-0.8	0.3
Mineral and other dietary supplements	0.6	0.8	1.5	0.9	0.2	1.2
Mother’s age at death	0.6	0.7	1.1	1.0	0.9	-0.5
Eye problems/disorders: Glaucoma	0.6	0.8	1.4	0.5	-0.8	1.2
Illnesses of father: High blood pressure	0.6	0.7	1.6	-0.7	-1.3	0.4
Irritability	0.6	1.0	2.7	0.3	0.6	1.6
Depressed Affect (Nagel 2018)	0.5	1.1	1.7	-1.3	-0.9	0.8
Lupus	0.5	0.8	1.4	0.6	0.7	1.2
Neuroticism (2016)	0.5	0.8	1.6	-1.2	-0.8	-0.1
Primary Biliary Cirrhosis	0.5	0.7	1.1	-0.5	0.9	-1.1
Allergy or Eczema	0.5	1.2	2.2	1.5	0.9	0.7
Hand grip strength (left)	0.5	1.4	3.6	-0.2	-0.6	-1.9
Ever used hormone-replacement therapy (HRT)	0.5	0.6	1.5	-1.2	-0.3	-0.5
Eye problems/disorders: Diabetes related eye disease	0.5	0.5	1.0	-0.8	0.0	-1.0
Medication: Metformin	0.5	0.7	1.4	-1.2	0.7	-0.4
Pack years adult smoking proportion	0.5	0.7	1.2	0.8	-0.5	1.1
Impedance of leg (right)	0.5	2.6	7.3	-0.4	-2.7	-0.5
Trunk fat percentage	0.5	2.2	5.8	0.8	0.3	2.4
Age when periods started (menarche)	0.5	1.2	2.1	-1.5	-1.0	-0.5
Trunk fat mass	0.5	2.0	4.2	1.0	0.9	2.0
Hair/balding pattern: Pattern 2	0.5	0.6	0.9	-0.4	-0.9	-0.9
Qualifications: None of the above	0.5	1.0	1.7	-1.3	-0.9	0.7
Worrier / anxious feelings	0.5	0.9	1.8	-0.3	-1.0	1.3
Noisy workplace	0.5	0.7	0.7	0.8	0.8	0.8
Asthma	0.5	0.9	2.0	0.8	1.4	0.1
Medication: Ibuprofen (e.g. Nurofen)	0.5	0.7	1.1	0.9	1.1	-0.3
Standing height	0.5	5.3	7.8	2.1	2.8	-2.0
Mouth/teeth dental problems: Bleeding gums	0.5	0.6	1.3	-0.6	0.4	-1.1
Eye problems/disorders: None of the above	0.5	0.5	0.8	0.1	-0.9	0.9
Whole body fat mass	0.5	2.1	5.1	0.9	0.6	2.2
Comparative height size at age 10	0.5	2.7	5.2	0.8	2.3	-1.5
Leg pain on walking	0.5	0.6	0.9	0.4	1.0	0.9
Illness, injury, bereavement, stress in last 2 years	0.5	0.6	1.0	-1.0	0.2	-0.9
Whole body fat-free mass	0.5	3.0	7.6	1.2	2.8	-0.2
Long-standing illness, disability or infirmity	0.5	0.7	2.2	-0.0	1.5	0.2
Back pain experienced in last month	0.5	0.7	1.6	0.1	-0.7	1.3
Whole body water mass	0.5	2.8	7.1	1.2	2.7	-0.0
Ever taken oral contraceptive pill	0.5	0.5	1.0	0.1	1.0	-0.7
High cholesterol (Self-reported)	0.5	0.9	1.5	-0.7	-0.9	1.2
Average weekly beer plus cider intake	0.5	0.7	1.1	0.1	-1.0	-1.0
Height	0.4	7.6	14.4	1.6	2.4	-3.8
Systolic Blood Pressure	0.4	1.8	4.6	-0.2	0.9	-2.1
Average weekly spirits intake	0.4	0.5	1.0	-0.6	0.3	-1.0
Hearing difficulty/problems: Yes	0.4	0.6	1.8	-1.3	-0.3	-0.1
Relative age of first facial hair	0.4	0.8	2.0	-0.6	1.4	-0.3
Taking other prescription medications	0.4	0.7	0.9	0.7	0.8	1.0
Bilateral oophorectomy (both ovaries removed)	0.4	0.4	0.7	-0.8	-0.4	0.6
Body mass index (BMI)	0.4	1.6	4.4	0.2	0.5	2.1
Weight	0.4	1.8	2.9	1.1	1.7	1.1
Arm fat percentage (right)	0.4	1.6	4.2	0.6	0.5	2.1
Trunk fat-free mass	0.4	2.2	5.6	0.7	2.4	-0.7
Medication: Cholesterol lowering	0.4	0.6	1.2	-1.1	0.7	-0.1
Trunk predicted mass	0.4	2.1	5.3	0.7	2.3	-0.8
Emphysema/chronic bronchitis	0.4	0.5	1.0	-0.2	0.7	-1.0
Medication: Blood pressure	0.4	0.8	1.8	0.7	1.4	0.1
Leg fat mass (right)	0.4	1.4	4.1	0.3	0.2	2.0
Commuting to job workplace: Car/motor vehicle	0.4	0.4	0.7	0.8	-0.6	-0.6
Medication: Aspirin	0.4	0.5	1.1	-0.1	0.5	-1.1
Arm fat percentage (left)	0.4	1.7	4.2	0.7	0.6	2.1
Loneliness, isolation	0.4	0.6	1.4	-1.2	-0.6	0.1
Mouth/teeth dental problems: Mouth ulcers	0.4	0.6	1.1	1.0	-0.5	0.6
Asthma (self-reported)	0.4	0.8	1.8	0.7	1.3	0.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.4	0.9	2.5	-1.6	0.2	-0.3
Guilty feelings	0.4	0.6	1.1	0.4	-0.6	1.0
Basal metabolic rate	0.4	2.4	6.1	1.1	2.5	0.1
Unable to work because of sickness or disability	0.4	0.5	1.2	-0.5	0.3	1.1
Alzheimer’s Disease (including proxy)	0.3	0.5	0.8	-0.1	0.9	-0.8
Verbal and Numeric Reasoning (VNR)	0.3	0.7	1.9	0.5	0.2	-1.4
Fasting Glucose	0.3	0.3	0.6	-0.2	0.8	-0.6
Respiratory disease	0.3	0.6	1.0	-0.2	0.9	-1.0
Lung FVC	0.3	1.8	3.6	-1.9	-1.2	-0.4
Hair Pigment	0.3	8.0	12.3	-0.7	3.3	-3.5
Medication for hormone replacement therapy	0.3	0.3	0.8	0.3	0.3	-0.9
Hand grip strength (right)	0.3	0.7	1.1	0.1	-1.1	-0.9
Waist circumference	0.3	1.0	2.1	0.3	1.5	0.9
Forced vital capacity (FVC)	0.3	1.2	2.5	-0.4	1.0	-1.6
Heel bone mineral density (BMD) T-score, automated (right)	0.3	0.7	1.6	0.3	0.5	1.3
Impedance of arm (right)	0.3	1.3	3.3	1.8	0.8	0.0
Hip circumference	0.3	1.4	1.7	1.1	1.3	1.2
Alcohol intake versus 10 years previously	0.3	0.5	1.3	-1.2	-0.3	-0.2
Father’s age at death	0.3	0.4	0.6	0.3	-0.7	-0.8
Number of live births	0.3	0.4	0.8	-0.9	-0.6	0.3
Arm fat mass (right)	0.3	1.4	3.0	0.6	1.0	1.7
Tense / ‘highly strung’	0.3	0.5	0.8	0.8	-0.0	0.9
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.4	0.9	-0.3	-1.0	0.4
Birth weight of first child	0.3	0.6	1.6	-1.3	-0.5	-0.3
Loud music exposure frequency	0.3	0.3	0.5	0.6	0.7	-0.3
Medication for cholesterol, blood pressure or diabetes	0.3	0.5	1.2	0.6	-1.1	0.1
Exposure to tobacco smoke outside home	0.3	0.4	0.6	0.3	-0.7	0.8
Number of children fathered	0.3	0.3	0.5	0.7	0.6	0.3
Shortness of breath walking on level ground	0.3	0.4	1.0	-1.0	-0.4	0.1
Heart disease (mother)	0.3	0.4	0.8	-0.2	0.9	-0.5
Suffer from ‘nerves’	0.3	0.5	1.2	-0.3	-1.1	0.4
Illnesses of siblings: Diabetes	0.3	0.4	0.9	-0.0	0.6	1.0
Mood swings	0.3	0.5	0.9	-1.0	0.2	-0.6
Qualifications: nursing, teaching	0.3	0.5	1.0	0.5	1.0	-0.3
Arm fat mass (left)	0.3	1.2	2.8	0.5	0.7	1.7
Tinnitus: Yes, now most or all of the time	0.3	0.3	0.7	-0.2	0.8	-0.5
Myopia	0.3	0.4	1.1	0.0	1.0	0.5
Pain experienced in last month	0.3	0.6	1.2	0.4	0.6	-1.1
Heart disease (siblings)	0.3	0.3	0.8	-0.2	-0.3	-0.9
Pack years of smoking	0.3	0.4	0.9	0.4	-0.5	0.9
Leg fat mass (left)	0.3	1.3	4.0	0.0	0.0	2.0
Neuroticism (Nagel 2018)	0.2	0.4	1.0	-0.1	-0.5	1.0
Cardiovascular Disease	0.2	0.8	1.4	0.5	-0.8	1.2
Lung FEV1/FVC ratio	0.2	1.2	3.0	-1.7	-0.7	-0.4
Neuroticism	0.2	0.5	0.8	-0.6	-0.5	0.9
Sensitivity / hurt feelings	0.2	0.3	0.9	-0.0	0.9	0.4
Severe depression (siblings)	0.2	0.3	0.5	0.5	-0.7	0.2
Diverticular disease/diverticulitis (self-reported)	0.2	0.2	0.4	0.7	-0.1	-0.4
High blood pressure (mother)	0.2	0.2	0.4	-0.6	-0.5	0.0
Ever unenthusiastic/disinterested for a whole week	0.2	0.3	0.5	-0.7	-0.2	0.5
Financial difficulties in last 2 years	0.2	0.3	0.7	0.9	0.4	0.1
Hayfever/allergic rhinitis (self-reported)	0.2	0.3	0.7	0.3	0.8	-0.0
Medication: Ramipril	0.2	0.3	0.6	-0.7	-0.4	0.2
Neuroticism score	0.2	0.4	0.8	-0.9	-0.3	0.3
Happiness	0.2	0.3	0.4	0.7	-0.2	0.6
Impedance of arm (left)	0.2	1.0	2.4	1.5	0.6	-0.5
Hair/balding pattern: Pattern 4	0.2	0.5	1.0	0.7	0.2	1.0
Headache pain in last month	0.2	0.3	0.5	-0.5	-0.1	0.7
Gout (self-reported)	0.2	0.3	0.7	-0.1	-0.9	0.4
Comparative body size at age 10	0.2	0.6	1.0	-1.0	0.4	0.7
Worry too long after embarrassment	0.2	0.3	0.6	0.2	-0.4	0.8
Health satisfaction	0.2	0.2	0.5	-0.4	-0.7	0.2
Medication: Allopurinol	0.2	0.2	0.5	-0.5	-0.7	0.0
Arm predicted mass (right)	0.2	0.9	2.4	0.6	1.6	0.1
Alcohol intake frequency.	0.2	0.4	0.7	-0.8	0.3	0.7
Knee pain experienced in last month	0.2	0.3	0.4	0.4	0.7	0.5
Hypertension (Self-reported)	0.2	0.6	1.2	0.5	-0.6	1.1
Illnesses of father: Heart disease	0.2	0.3	0.7	0.3	-0.1	-0.8
Breast cancer (self-reported)	0.2	0.3	0.5	-0.7	0.5	0.3
Osteoarthritis (self-reported)	0.2	0.3	0.8	-0.1	0.3	0.9
Number of self-reported non-cancer illnesses	0.2	0.3	0.4	-0.5	0.7	0.4
Commuting to job workplace: Public transport	0.2	0.2	0.4	0.6	-0.2	0.4
Alcohol drinker status: Never	0.2	0.3	0.4	0.7	0.6	-0.1
Arm predicted mass (left)	0.2	0.8	1.8	0.6	1.4	0.3
Worry (Nagel 2018)	0.1	0.2	0.4	0.3	-0.6	0.4
Alzheimer’s Disease (in father)	0.1	0.2	0.4	0.3	0.6	0.1
Ovarian Cancer	0.1	0.2	0.3	0.5	0.4	-0.2
Chronotype (morning person)	0.1	0.3	1.0	0.1	0.0	-1.0
Tanning	0.1	1.1	1.9	1.4	1.1	0.4
Number of treatments/medications taken	0.1	0.2	0.4	-0.1	-0.5	0.6
Diabetes (mother)	0.1	0.1	0.2	0.0	0.3	0.5
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.1	0.2	0.2	0.4	0.5
Tinnitus: Yes, but not now, but have in the past	0.1	0.2	0.5	0.7	-0.0	0.1
High blood pressure	0.1	0.3	0.5	0.3	-0.5	0.7
Medication: Atenolol	0.1	0.1	0.2	-0.4	0.4	-0.3
Past tobacco smoking	0.1	0.1	0.4	0.1	-0.2	0.6
Nervous feelings	0.1	0.3	0.5	0.7	0.4	-0.3
Hearing difficulty/problems with background noise	0.1	0.1	0.3	0.1	0.6	0.1
Frequency of tiredness / lethargy in last 2 weeks	0.1	0.1	0.2	-0.4	0.1	0.5
Mouth/teeth dental problems: Dentures	0.1	0.2	0.4	-0.6	0.5	-0.1
Birth weight	0.1	0.1	0.2	-0.3	-0.5	0.3
Arm fat-free mass (right)	0.1	0.5	1.4	0.5	1.2	-0.0
Mouth/teeth dental problems: Loose teeth	0.1	0.1	0.3	-0.1	0.4	0.5
Family relationship satisfaction	0.1	0.2	0.5	0.1	-0.7	-0.2
Supplements: Vitamin C	0.1	0.1	0.3	0.0	0.3	-0.5
Commuting to job workplace: Walk	0.1	0.1	0.2	-0.1	0.2	0.5
Medication: Aspirin	0.1	0.1	0.3	-0.2	0.4	-0.5
Medication: Gliclazide	0.1	0.1	0.3	-0.3	0.6	0.0
Illnesses of father: None of the above (group 1)	0.1	0.1	0.2	0.2	0.4	0.4
Pain type(s) experienced in last month: Hip pain	0.1	0.1	0.3	-0.0	0.6	0.2
Ever smoked	0.1	0.2	0.5	-0.3	0.1	-0.7
Arm fat-free mass (left)	0.1	0.5	1.2	0.3	1.1	0.2
Ever depressed for a whole week	0.1	0.1	0.4	0.2	0.6	0.2
Vascular/heart problems diagnosed by doctor	0.1	0.3	0.6	-0.3	0.4	-0.8
Basal cell carcinoma (self-reported)	0.1	0.1	0.2	0.1	-0.3	-0.5
Impedance of whole body	0.1	0.6	1.5	0.5	-1.2	-0.4
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0
Body Mass Index (BMI) (2010)	0.0	0.0	0.0	0.0	0.0	0.0
Coronary Artery Disease (CAD)	0.0	0.0	0.0	0.0	0.0	0.0
HDL Cholesterol	0.0	0.0	0.0	0.0	0.0	0.0
LDL Cholesterol	0.0	0.0	0.0	0.0	0.0	0.0
Triglycerides	0.0	0.0	0.0	0.0	0.0	0.0
Type 2 Diabetes (T2D) (2012)	0.0	0.0	0.0	0.0	0.0	0.0
Diabetes (father)	0.0	0.0	0.1	-0.0	0.3	-0.0
Mouth/teeth dental problems	0.0	0.1	0.1	0.2	-0.0	0.3
Medication: Ventolin 100micrograms inhaler	0.0	0.0	0.1	-0.3	0.0	0.2
Wears glasses or contact lenses	0.0	0.0	0.1	0.1	0.1	0.2

Hub : Genes

POP7

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Trait associations