Hub : Genes

POU6F1

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.0700 0.0240 1.1e-04 0.044 0.042 0.027 0.040 0.024 4.1e-06 6.6e-06 2.4e-04 1.1e-05 6.2e-04
2 GTEx Cells Transformed fibroblasts 0.1830 0.0560 4.7e-04 0.125 NA 0.140 NA 0.152 1.2e-09 NA 1.1e-10 NA 1.7e-11
3 GTEx Skin Not Sun Exposed Suprapubic 0.1730 0.0660 3.3e-03 0.017 NA 0.017 NA 0.056 3.8e-02 NA 3.6e-02 NA 5.0e-04
4 GTEx Skin Sun Exposed Lower leg 0.1690 0.0540 2.3e-04 0.023 NA 0.087 NA 0.109 4.8e-03 NA 1.1e-07 NA 2.5e-09
5 METSIM Adipose 0.0342 0.0145 2.7e-03 0.017 0.013 0.025 0.014 0.017 1.3e-03 3.7e-03 9.6e-05 2.9e-03 1.0e-03
6 NTR Blood 0.0289 0.0111 2.9e-04 0.012 0.009 0.005 0.009 0.006 6.8e-05 5.9e-04 8.5e-03 5.3e-04 3.5e-03
7 YFS Blood 0.1248 0.0270 5.6e-17 0.068 0.072 0.092 0.085 0.091 3.6e-21 1.6e-22 1.2e-28 1.8e-26 3.2e-28
8 TCGA Testicular Germ Cell Tumors 0.2220 0.0940 3.7e-04 0.061 0.093 0.059 NA 0.061 3.5e-03 3.5e-04 3.9e-03 NA 3.5e-03

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bipolar Disorder (2018) 4.1 6.5 14.0 2.6 1.9 -0.2 3.1 -1.7 -3.7 -2.6 2.8
Bipolar Disorder or Schizophrenia 2.4 5.8 13.9 2.8 1.7 -0.8 3.0 -2.3 -3.7 -2.0 1.7
Depressed Affect (Nagel 2018) 2.4 5.0 8.0 -2.4 -2.0 -2.3 -2.6 1.0 2.8 2.6 -1.2
Depression (Nagel 2018) 0.4 0.6 1.8 0.8 0.5 -0.7 -0.5 -0.6 -0.6 -1.3 0.7
Intelligence (Savage-Jansen 2018) 0.5 1.4 6.7 -0.8 1.0 -0.3 -1.0 -1.2 2.6 -0.7 0.3
Neuroticism (Nagel 2018) 2.5 5.9 9.5 -3.1 -1.9 -2.7 -2.5 1.7 2.7 2.9 -1.2
Schizophrenia (2018) 0.6 1.2 3.1 1.6 0.6 -0.7 1.4 -0.8 -1.8 -0.4 -0.2
Schizophrenia vs Biploar Disorder 1.2 1.6 5.4 0.6 -0.6 2.0 0.3 0.5 0.9 1.2 -2.3
Worry (Nagel 2018) 0.5 1.1 2.3 -1.5 -0.6 -1.2 -0.7 1.2 0.7 1.4 0.1
Alzheimer’s Disease (in mother) 0.5 0.6 2.2 0.0 0.7 -0.1 -1.5 -0.6 0.3 -0.0 -1.1
Alzheimer’s Disease (in father) 1.0 1.0 1.9 1.0 -1.4 0.5 0.6 1.2 -0.5 1.2 -1.3
Alzheimer’s Disease (including proxy) 0.5 0.7 3.0 1.0 0.4 -0.2 -1.2 -0.3 0.2 0.3 -1.7
Crohns Disease (2017) 0.7 1.6 5.5 2.3 -0.9 -0.4 -0.0 -1.6 -1.3 -0.0 -1.4
Irritable Bowel Disease (IBD) 0.7 1.6 5.6 1.9 0.2 -1.2 0.6 -1.0 -2.4 -1.0 0.4
Ulcerative Colitis (UC) 1.4 2.6 8.1 0.9 1.2 -1.2 1.1 0.0 -2.8 -1.9 2.0
Major Depression (MDD) 2.0 2.4 4.1 -1.8 -1.5 -0.9 -1.8 1.2 1.2 2.0 -1.7
Reaction Time 0.4 0.7 1.8 0.6 -0.3 0.6 1.3 1.2 -0.3 -0.2 -1.4
Verbal and Numeric Reasoning (VNR) 0.4 1.0 4.8 -0.9 1.3 0.3 -0.4 0.2 2.2 -0.2 0.7
Breast Cancer 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
Ovarian Cancer 1.0 1.4 3.7 -1.0 1.9 -0.6 -0.4 -0.9 -1.0 -1.4 1.4
Prostate Cancer 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
Age at First Birth 0.9 1.3 3.1 0.4 0.8 -0.1 1.6 -0.7 -1.8 -0.8 1.7
Bipolar Disorder (2011) 3.3 3.2 7.5 1.2 2.7 -1.2 1.8 -1.2 -1.8 -2.7 0.0
Body Mass Index (BMI) (2010) 1.7 2.4 6.5 0.8 2.5 -0.2 -0.5 -1.5 -0.1 -2.5 1.7
Coronary Artery Disease (CAD) 0.3 0.3 1.0 0.2 0.7 0.8 -0.2 -0.2 1.0 -0.4 0.3
Crohns Disease (2012) 0.5 0.7 2.8 1.1 0.3 -0.3 -1.1 -1.7 -0.6 -0.4 0.1
Mean Putamen Volume 0.3 0.3 1.6 -1.3 -0.4 -0.1 0.5 0.7 -0.1 0.4 -0.1
Fasting Glucose 0.4 0.4 1.2 0.5 0.4 0.6 0.8 0.6 -0.6 -0.2 1.1
HbA1C 0.5 0.6 2.0 -0.4 0.1 -0.6 0.0 1.4 -1.2 -0.5 0.6
HDL Cholesterol 0.8 1.3 2.8 -0.5 -1.5 1.3 -0.5 0.8 1.2 1.0 -1.7
LDL Cholesterol 1.8 2.8 5.4 -1.4 -2.2 -0.5 -2.3 1.9 1.5 1.7 -1.1
Lupus 0.5 0.8 1.5 0.9 -1.0 -0.6 -0.1 1.2 0.7 1.1 -1.1
Neuroticism (2016) 3.0 4.4 7.8 -2.8 -1.8 -2.3 -0.9 1.3 2.6 2.8 -1.5
Primary Biliary Cirrhosis 0.8 1.1 2.6 1.3 1.6 -1.1 0.3 -1.2 -0.2 -1.2 0.2
Rheumatoid Arthritis 1.4 1.9 4.5 0.0 -2.1 -0.6 0.3 1.3 1.1 1.7 -2.0
Schizophrenia (2014) 1.3 2.8 7.0 2.6 0.9 0.1 2.2 -1.4 -2.3 -1.4 0.6
Triglycerides 0.3 0.4 1.3 0.2 0.8 -0.2 -1.2 -0.0 0.0 -0.9 0.8
Type 2 Diabetes (T2D) (2012) 0.4 0.4 1.5 0.2 0.9 -1.2 -0.6 0.1 0.3 -0.5 0.5
Ulcerative Colitis 1.4 2.1 6.0 -0.5 1.4 -0.9 0.7 -0.1 -2.1 -1.6 2.5
Blood Eosinophil Count 0.3 2.3 5.2 2.2 1.8 0.2 1.4 -1.1 -0.8 -2.3 1.0
Blood Platelet Count 3.5 40.4 118.8 7.7 0.9 7.0 10.9 0.0 -7.5 -4.1 4.7
Blood Red Count 0.1 1.1 4.5 -0.0 1.1 0.5 -1.3 -1.1 -2.1 -0.7 -0.1
Blood White Count 0.5 3.9 13.1 2.8 1.0 0.6 3.6 -0.8 -1.8 -2.0 1.0
Heel T-Score 0.5 4.3 16.4 0.9 -1.9 -0.6 0.2 0.6 2.5 2.5 -4.0
BMI 1.8 10.3 25.5 0.6 5.0 -0.1 0.3 -4.2 -1.6 -4.7 3.7
Height 0.6 12.1 30.6 1.2 -5.5 3.6 1.0 2.7 2.8 3.6 -4.9
Waist Hip Ratio (WHR) 0.2 0.7 2.1 -0.1 1.1 0.9 0.1 0.3 -0.5 -1.2 1.5
Systolic Blood Pressure 0.6 3.0 9.1 -2.3 -0.7 -2.2 -0.9 0.3 3.0 1.2 -1.3
Smoking Status 0.5 1.2 3.8 -0.3 -1.5 -0.1 0.4 2.0 -1.0 1.0 -1.2
Allergy or Eczema 0.7 1.9 4.4 -0.2 -1.0 -1.9 -0.7 0.2 1.8 2.1 -1.4
Cardiovascular Disease 1.4 4.6 10.9 -2.4 2.5 -3.3 -2.1 -1.1 2.1 -1.3 1.5
Hypothyroidism (self reported) 0.3 0.6 1.4 0.2 -0.1 -0.2 -1.1 0.1 1.2 0.9 -1.2
Respiratory disease 0.4 0.8 3.8 0.5 1.0 -1.9 1.0 -0.4 -0.2 -0.7 0.2
Type 2 Diabetes (T2D) (2018) 0.4 0.8 2.6 0.3 1.6 0.2 0.6 -1.0 -0.4 -0.8 1.2
Lung FEV1/FVC ratio 0.4 1.8 6.3 -1.7 -0.0 1.2 -2.5 -0.2 1.8 0.7 -0.1
Lung FVC 0.8 3.9 13.0 -3.6 -0.9 -1.8 -2.3 -0.5 1.9 1.8 -1.3
Neuroticism 2.4 5.8 11.9 -3.3 -2.1 -1.8 -1.6 2.1 2.7 3.5 -1.2
Chronotype (morning person) 0.8 1.9 5.7 1.0 2.2 0.6 0.7 -1.2 0.0 -1.2 2.4
Hair Pigment 0.0 1.0 4.6 -1.3 -0.4 0.9 -0.6 2.1 0.4 0.4 0.2
Tanning 0.2 3.0 7.5 -0.4 2.7 1.0 0.7 -1.3 -1.8 -1.7 2.6
Hand grip strength (left) 1.0 2.5 5.7 -0.5 -2.1 1.8 -1.1 0.5 2.0 2.4 -1.0
Number of treatments/medications taken 1.0 1.7 7.7 -1.6 1.4 -2.8 -0.5 0.0 -0.2 -0.8 0.9
Average weekly spirits intake 0.6 0.8 2.3 -1.5 -0.6 -0.7 -1.4 0.5 0.6 0.4 0.6
Sensitivity / hurt feelings 0.5 0.9 2.0 -1.1 -0.3 -0.9 -0.4 0.8 1.4 1.4 -0.7
Frequency of depressed mood in last 2 weeks 0.3 0.5 1.1 0.8 0.2 -0.2 0.2 -0.7 -1.0 -1.0 0.6
Hearing difficulty/problems: Yes 1.2 1.8 6.8 -1.5 -0.3 -2.6 0.1 1.3 1.3 0.9 -1.0
Relative age of first facial hair 0.7 1.5 6.6 -1.5 -0.6 -2.6 -0.9 -0.0 -0.7 1.1 -0.3
Other serious medical condition/disability diagnosed by doctor 1.1 1.4 4.1 -2.0 1.3 -0.4 -1.6 -0.5 -0.4 -1.2 0.8
Ever used hormone-replacement therapy (HRT) 2.5 3.2 5.8 1.2 1.9 0.8 1.7 -1.5 -2.2 -2.4 2.0
Ever had hysterectomy (womb removed) 2.7 3.0 10.0 -0.8 -1.1 -1.9 -3.2 -0.3 1.9 1.6 -1.6
Systolic blood pressure, automated reading 1.4 4.1 12.3 -2.4 -1.4 -1.2 -1.0 1.4 3.5 2.1 -1.8
Eye problems/disorders: Diabetes related eye disease 2.0 2.2 8.2 2.9 0.7 2.2 0.8 0.0 -1.0 -1.6 -0.6
Angina 0.4 0.6 1.5 -1.2 0.4 -0.5 -0.9 0.0 -0.7 -0.5 1.0
Medication for hormone replacement therapy 1.3 1.5 4.8 -0.2 2.2 -0.4 0.5 -1.4 -0.7 -1.7 1.3
Vitamin and mineral supplements 0.2 0.3 0.9 -0.6 -0.3 -0.4 -0.6 1.0 -0.4 0.4 -0.0
Supplements: Zinc 0.3 0.3 1.1 1.1 -0.4 0.8 -0.3 -0.2 0.2 0.3 -0.8
Medication: Co-codamol 1.6 1.9 3.5 0.9 1.3 1.2 0.8 -1.4 -1.9 -1.8 1.5
Medication: Metformin 0.4 0.6 2.0 1.4 0.8 -0.3 0.6 -0.4 -0.5 -0.9 0.3
Diabetes (father) 0.8 0.9 3.8 -1.9 -0.4 0.4 -0.8 0.4 1.3 0.9 -0.3
Diabetes (mother) 0.5 0.6 1.1 -0.5 0.7 -0.4 0.5 -0.8 -1.0 -1.0 0.8
Severe depression (siblings) 0.3 0.3 0.7 -0.6 -0.2 -0.1 0.4 0.8 -0.8 -0.4 0.6
Pack years adult smoking proportion 1.1 1.6 3.9 -0.5 -1.4 0.1 -0.8 0.6 1.9 1.6 -2.0
Impedance of leg (right) 0.7 3.2 7.8 1.3 -2.8 -0.4 0.6 1.5 0.5 2.5 -2.6
Leg fat-free mass (left) 0.3 1.4 3.6 0.2 1.4 1.8 0.5 -1.3 0.2 -1.9 0.6
Trunk fat percentage 1.3 5.3 16.5 2.1 3.4 -0.4 1.2 -2.1 -1.5 -4.1 1.4
Hand grip strength (right) 0.8 2.2 6.6 0.2 -2.0 1.4 -0.7 0.2 1.7 2.6 -1.4
Townsend deprivation index at recruitment 0.3 0.4 1.8 -0.0 -0.5 -0.2 0.7 -0.3 0.2 0.3 -1.3
Current tobacco smoking 0.9 1.5 2.9 -1.2 -1.5 -0.3 -1.7 0.1 1.3 1.2 -1.6
Average weekly fortified wine intake 0.4 0.5 2.5 -0.3 -0.4 -0.3 0.3 1.6 -0.6 0.4 0.6
Maternal smoking around birth 0.6 0.9 4.4 -0.3 -1.3 0.0 0.2 -0.1 0.1 0.8 -2.1
Fed-up feelings 0.2 0.3 1.0 -0.2 0.4 -0.2 -1.0 0.2 0.5 0.2 0.8
Frequency of unenthusiasm / disinterest in last 2 weeks 0.8 1.0 3.2 1.8 0.7 0.1 0.8 -0.8 -1.0 -1.3 0.6
Relative age voice broke 0.5 0.7 2.7 -0.4 -1.0 -0.2 -1.6 -0.8 0.1 0.7 -0.8
Taking other prescription medications 1.2 1.8 6.2 -2.5 -0.8 -1.0 -1.2 1.3 1.0 1.1 -1.3
Age when periods started (menarche) 1.6 3.8 8.4 0.5 -2.9 1.2 1.7 2.4 0.6 2.0 -2.8
Bilateral oophorectomy (both ovaries removed) 2.4 2.8 5.6 1.8 2.3 -0.2 0.8 -2.4 -0.7 -2.2 1.6
Heel bone mineral density (BMD) T-score, automated (left) 0.4 1.0 4.4 0.0 -0.5 0.0 -0.1 0.7 2.1 0.7 -1.5
Tinnitus: Yes, but not now, but have in the past 0.8 0.9 1.6 0.9 1.0 1.2 -0.5 -1.0 -0.0 -1.3 0.8
Qualifications: CSEs or equivalent 1.4 1.8 7.2 0.8 1.5 -0.1 1.4 -0.0 -2.7 -1.5 0.7
Serious illness, injury or assault to yourself 1.0 1.2 2.6 -1.6 1.0 0.3 0.5 -1.6 -0.8 -1.2 0.8
High blood pressure 1.5 4.2 13.9 -2.0 2.5 -3.7 -1.6 -1.6 1.3 -1.4 1.0
Hayfever, allergic rhinitis or eczema 0.9 2.0 5.0 0.8 -1.4 -1.3 0.3 0.6 1.8 2.2 -1.7
Multivitamins +/- minerals 0.5 0.6 2.0 0.9 -0.2 0.1 -0.3 -1.4 1.0 0.0 -0.9
Stomach or abdominal pain in last month 0.3 0.4 1.2 -0.3 0.6 -0.9 -0.7 -1.1 0.6 -0.3 -0.3
Supplements: Glucosamine 0.8 1.0 2.8 -0.6 -1.7 1.0 0.2 0.6 0.6 1.5 -1.0
Diverticular disease/diverticulitis (self-reported) 0.1 0.2 0.3 0.5 -0.4 -0.5 -0.1 0.5 -0.6 -0.2 -0.2
Medication: Atenolol 1.2 1.5 3.9 -0.1 1.5 -0.2 0.4 -1.1 -1.3 -2.0 1.5
Medication: Levothyroxine sodium 0.6 1.1 3.0 0.6 -0.5 -1.4 -0.8 0.9 1.7 0.7 -1.1
Sitting height 0.2 1.2 3.6 -0.7 -0.8 1.9 0.4 0.4 1.7 0.5 -1.1
Chronic bronchitis/emphysema (father) 1.2 1.4 3.3 0.5 1.8 -0.9 0.4 -0.4 -1.2 -1.2 1.8
High blood pressure (mother) 0.6 0.9 2.9 -0.9 1.0 0.6 -0.9 -0.1 0.0 -1.2 1.7
Body mass index (BMI) 2.0 8.7 23.1 0.7 4.8 -0.2 0.2 -3.2 -1.7 -4.8 3.1
Impedance of leg (left) 0.7 3.3 8.8 1.4 -3.0 0.3 0.9 1.3 0.2 2.3 -2.7
Leg predicted mass (left) 0.3 1.4 3.6 0.1 1.4 1.9 0.5 -1.2 0.3 -1.9 0.6
Trunk fat mass 1.2 5.2 16.1 2.2 3.3 0.5 1.3 -2.2 -1.2 -4.0 1.4
Waist circumference 1.4 5.1 16.0 1.2 3.1 1.0 0.5 -2.5 -1.2 -4.0 2.2
Number of incorrect matches in round 0.8 1.4 3.3 0.7 -1.6 0.4 1.2 1.8 -0.9 0.8 -1.2
Past tobacco smoking 0.5 0.9 3.1 0.7 1.3 0.5 -0.6 -0.8 1.8 -0.3 0.9
Alcohol usually taken with meals 0.1 0.1 0.2 0.4 0.3 -0.3 0.2 -0.5 0.2 -0.0 0.3
Nervous feelings 0.3 0.6 2.3 -1.5 0.3 -1.1 0.3 0.1 -0.3 0.5 0.7
Frequency of tenseness / restlessness in last 2 weeks 0.2 0.3 1.7 -0.6 -0.0 -1.3 0.2 -0.0 0.3 -0.4 0.2
Hearing difficulty/problems with background noise 0.6 1.0 2.4 -1.5 -0.2 -0.5 0.6 0.7 1.6 1.2 -1.0
Hair/balding pattern: Pattern 2 0.6 0.8 2.2 -0.3 0.9 0.3 0.5 -0.4 -1.3 -0.8 1.5
Had menopause 1.1 1.3 4.6 -0.7 -1.5 2.1 -0.5 1.6 -0.1 0.6 -0.4
Had other major operations 1.0 1.2 4.1 -0.2 -0.5 -0.4 -2.0 -0.3 1.1 1.5 -1.3
Forced vital capacity (FVC) 1.2 4.7 10.9 -1.2 -2.4 0.7 -1.4 -0.5 3.3 3.0 -2.8
Heel bone mineral density (BMD) T-score, automated (right) 0.6 1.3 4.5 1.7 -0.2 0.3 0.4 0.7 2.1 0.2 -1.6
Ever unenthusiastic/disinterested for a whole week 1.1 1.4 3.1 -1.8 -0.7 -1.0 -0.6 1.1 1.7 1.4 0.2
Qualifications: None of the above 0.5 1.1 3.3 -1.5 -1.0 -0.7 -0.2 1.0 -1.8 0.4 -0.5
Financial difficulties in last 2 years 0.3 0.4 1.6 -0.8 -0.7 -0.4 -0.0 0.1 0.6 0.5 -1.3
Mouth/teeth dental problems 0.8 1.3 4.3 1.5 1.2 0.2 0.5 -2.1 0.9 -1.0 0.5
Heart attack 0.4 0.5 2.7 1.6 -0.2 0.3 0.6 0.2 -0.2 -0.5 0.5
Allergy 0.6 1.4 3.1 -0.8 1.0 1.8 -1.1 -0.8 -1.0 -1.6 1.0
Pain all over the body in last month 0.8 0.8 2.4 0.3 0.4 -0.4 1.1 -0.8 -1.5 -1.2 0.8
Diabetes (self-reported) 1.2 1.8 3.1 1.5 1.8 0.3 0.6 -1.3 -1.7 -1.4 1.5
Hayfever/allergic rhinitis (self-reported) 0.5 0.7 2.6 1.3 -0.6 0.4 0.3 -0.3 1.6 0.2 -0.3
Medication: Ramipril 3.4 4.4 7.8 -0.1 2.3 -1.0 1.3 -2.8 -2.4 -2.6 2.5
Medication: Simvastatin 0.3 0.5 1.5 -0.8 0.6 0.3 -0.3 -0.1 -0.7 -0.9 1.2
Fluid intelligence score 0.3 0.7 4.4 0.4 0.8 0.1 -0.7 -0.0 2.1 -0.1 -0.3
Illnesses of siblings 0.2 0.3 1.4 -0.6 -0.3 1.2 -0.0 0.0 0.6 0.2 -0.3
Neuroticism score 1.8 3.7 9.4 -2.2 -2.1 -0.5 -0.3 2.4 1.7 3.1 -1.2
Weight 0.6 3.0 9.0 1.1 2.3 1.5 0.7 -2.1 -0.4 -3.0 1.0
Impedance of arm (right) 0.9 4.1 7.9 1.4 -2.8 -1.2 1.5 2.2 1.6 2.3 -2.5
Arm fat percentage (right) 1.6 6.2 18.1 1.3 4.0 -1.2 0.6 -2.5 -1.1 -4.3 2.1
Trunk fat-free mass 0.2 1.2 8.3 -0.2 0.1 2.9 0.2 -0.8 0.7 -0.5 -0.2
Hip circumference 0.8 3.4 10.3 1.5 2.1 1.5 1.3 -2.2 -0.8 -3.2 0.9
Time employed in main current job 0.5 0.6 1.5 -1.0 -0.6 0.7 -0.3 1.2 1.1 0.6 0.1
Alcohol intake versus 10 years previously 0.3 0.4 1.1 -1.1 0.8 -0.3 0.4 -0.4 -0.7 -0.7 0.6
Father’s age at death 0.7 1.0 2.5 1.1 1.6 -0.6 0.4 -0.7 -0.7 -1.5 0.4
Worrier / anxious feelings 0.2 0.5 1.5 0.4 0.1 0.5 1.2 1.0 -0.3 -0.2 0.8
Frequency of tiredness / lethargy in last 2 weeks 0.3 0.5 0.9 -0.4 -0.2 -1.0 -0.8 -0.9 0.4 0.2 -0.9
Falls in the last year 1.3 1.8 3.3 -1.7 0.1 -1.8 -1.5 -1.8 0.6 -0.3 -1.5
Hair/balding pattern: Pattern 3 1.4 2.0 5.4 0.0 -2.3 -0.3 -0.6 1.9 -0.0 1.8 -1.9
Number of live births 0.4 0.6 2.0 0.9 -0.8 0.5 0.6 -0.4 -0.4 0.2 -1.4
Forced expiratory volume in 1-second (FEV1) 1.1 3.7 11.1 -1.3 -1.5 1.5 -1.5 -1.0 3.3 2.4 -1.8
Pulse rate 2.8 4.7 6.7 1.9 2.4 1.5 2.5 -2.5 -1.8 -2.6 1.9
Happiness 0.6 0.7 3.1 0.5 -0.5 1.7 1.0 0.2 -0.7 0.4 -0.7
Noisy workplace 1.0 1.2 3.3 -0.4 1.1 -0.0 1.1 -0.2 -1.8 -1.1 1.5
Qualifications: A levels/AS levels or equivalent 0.2 0.5 2.3 1.1 0.5 0.5 -0.2 -0.3 1.5 0.3 -0.0
Serious illness, injury or assault of a close relative in last 2 years 1.8 2.1 8.2 -1.0 1.5 0.0 1.4 -0.4 -1.1 -1.4 2.9
Mouth/teeth dental problems: Dentures 0.7 1.3 3.0 -1.7 -0.1 -0.8 -1.1 1.5 -1.7 -0.3 0.2
Asthma 0.6 1.1 6.8 0.4 0.5 -2.6 0.4 -0.3 1.1 -0.0 -0.5
Medication: Ibuprofen (e.g. Nurofen) 0.5 0.7 1.6 0.5 0.9 -0.7 0.7 -0.6 -0.4 -1.1 1.3
Medication: Cholesterol lowering 0.3 0.5 1.6 0.0 0.9 0.0 0.0 -0.5 -0.9 -1.3 0.8
Depression (self-reported) 0.9 1.0 3.2 -0.9 -0.7 -0.3 -0.6 0.6 1.8 1.4 -0.9
Medication: Lansoprazole 1.9 2.1 7.0 1.0 2.6 -1.3 0.1 -0.5 -1.0 -1.5 2.0
Prospective memory result 0.8 0.9 4.8 -2.2 -0.6 -0.3 0.1 0.7 -0.9 1.0 0.2
Lung cancer (father) 1.0 1.2 2.2 0.8 0.2 -0.9 1.1 -1.5 -1.4 -1.4 0.9
Illnesses of mother 0.9 1.1 2.7 -0.5 -1.5 0.5 -0.6 0.9 1.4 1.7 -0.6
Forced expiratory volume in 1-second (FEV1), Best measure 1.2 3.8 11.8 -1.4 -1.5 0.5 -2.0 -1.0 3.4 2.5 -1.9
Pulse wave Arterial Stiffness index 1.0 1.2 3.8 -1.6 -0.6 1.1 2.0 0.6 0.5 0.5 -0.7
Impedance of arm (left) 0.8 3.9 6.9 1.3 -2.6 -0.8 1.3 2.4 1.5 2.3 -2.6
Arm fat mass (right) 1.2 5.0 15.6 1.1 3.5 0.1 0.6 -2.6 -0.9 -3.9 1.7
Trunk predicted mass 0.2 1.2 8.3 -0.2 0.1 2.9 0.3 -0.8 0.7 -0.5 -0.1
Standing height 1.1 10.4 23.0 0.9 -4.8 3.8 1.0 2.3 2.9 3.3 -4.4
Length of working week for main job 0.8 0.8 1.9 0.3 0.5 1.1 -0.6 -0.5 -1.1 -1.1 1.4
Exposure to tobacco smoke at home 0.7 0.7 2.1 0.9 -1.1 0.6 -0.9 -0.5 -0.1 0.6 -1.4
Breastfed as a baby 0.9 1.1 4.4 0.0 -0.1 1.5 2.1 1.0 -0.7 -0.3 0.5
Tense / ‘highly strung’ 1.0 1.6 3.6 -0.2 -1.5 1.0 1.9 1.4 0.6 1.6 -1.1
Seen doctor (GP) for nerves, anxiety, tension or depression 0.7 1.1 3.7 -0.0 1.9 0.5 1.3 -0.2 -0.8 -0.7 1.5
Hair/balding pattern: Pattern 4 0.3 0.8 2.0 -0.9 -1.0 -0.5 -1.0 1.4 0.2 0.7 0.9
Birth weight of first child 0.3 0.5 1.4 0.6 -0.2 0.3 -0.6 -1.2 1.0 -0.4 -0.7
Peak expiratory flow (PEF) 0.6 1.3 3.6 -1.3 -0.4 1.2 -0.1 -1.0 1.9 1.6 -0.4
Pulse wave reflection index 2.9 3.6 11.0 -3.3 -0.9 -0.7 -1.0 2.1 2.4 1.9 -1.3
Ever highly irritable/argumentative for 2 days 1.7 2.1 3.5 1.8 1.7 1.7 0.3 -0.7 -0.4 -1.9 1.9
Loud music exposure frequency 0.1 0.1 0.2 0.1 0.2 -0.1 0.1 -0.4 0.0 -0.3 0.4
Qualifications: O levels/GCSEs or equivalent 1.2 2.0 6.0 2.5 1.6 1.0 0.5 -1.2 1.2 -1.3 1.1
Mouth/teeth dental problems: Bleeding gums 0.3 0.3 1.1 0.5 -0.3 0.1 1.1 0.9 0.4 0.5 -0.3
Blood clot in the leg (DVT) 1.0 1.3 3.8 0.5 0.7 1.5 0.7 -0.0 -1.2 -1.4 1.9
Medication: Paracetamol 0.6 0.9 3.8 -1.4 0.0 -2.0 -0.5 -0.4 0.9 0.3 -0.7
Headache pain in last month 1.2 2.1 4.5 -2.1 -0.4 -2.1 -2.1 -0.0 1.3 0.9 -1.0
Medication for cholesterol, blood pressure or diabetes 0.9 1.6 3.4 -0.1 -1.4 0.9 -0.5 1.3 1.8 1.8 -1.1
Glaucoma (self-reported) 1.2 1.4 4.5 -0.6 -1.1 -0.1 -0.3 1.0 2.1 1.4 -1.6
Gout (self-reported) 0.5 0.7 1.9 1.2 -0.2 0.5 1.4 0.4 0.5 0.0 -1.2
Hypothyroidism/myxoedema (self-reported) 0.8 1.6 4.6 -0.1 -0.8 -0.4 -1.4 0.9 2.1 1.7 -1.4
Medication: Amlodipine 1.2 1.7 5.1 0.6 1.8 -2.3 -0.8 -0.9 -0.8 -1.6 0.7
Medication: Ventolin 100micrograms inhaler 1.8 2.3 3.8 0.6 2.0 -1.7 -0.9 -1.7 -1.0 -1.6 2.0
Birth weight 0.5 1.2 2.4 0.4 -1.4 1.2 1.2 1.6 -0.1 1.1 -0.9
Chronic bronchitis/emphysema (mother) 1.4 1.6 3.5 -1.1 -1.9 -1.1 1.2 0.9 -0.7 1.6 -1.3
High blood pressure (siblings) 0.4 0.6 3.9 -0.1 0.1 -2.0 -0.2 -0.5 0.6 0.3 -0.3
Forced vital capacity (FVC), Best measure 1.2 4.2 10.2 -1.4 -2.1 -0.0 -1.6 -0.4 3.2 2.9 -2.5
Body fat percentage 1.7 6.8 20.2 2.1 3.8 -0.3 1.0 -2.7 -1.8 -4.5 1.9
Leg fat percentage (right) 1.6 5.8 15.5 1.5 3.8 -0.4 0.5 -2.6 -1.6 -3.9 2.1
Arm fat-free mass (right) 0.4 1.9 9.1 0.2 1.0 3.0 0.5 -1.5 -0.3 -1.5 0.4
Exposure to tobacco smoke outside home 0.2 0.3 0.6 0.3 -0.4 -0.8 -0.3 -0.7 -0.4 0.2 -0.6
Comparative body size at age 10 0.3 1.0 3.0 0.8 1.2 -0.6 -0.5 -0.9 1.7 -0.7 1.0
Number of full brothers 0.7 0.9 2.1 0.7 1.5 0.2 1.0 -0.3 -0.9 -1.3 0.7
Worry too long after embarrassment 4.3 7.3 14.4 -3.6 -3.0 -1.6 -0.6 2.7 2.4 3.8 -2.5
Seen a psychiatrist for nerves, anxiety, tension or depression 0.2 0.3 1.0 -1.0 -0.2 -0.9 -0.6 0.0 0.0 0.5 -0.3
Wheeze or whistling in the chest in last year 0.4 0.7 2.4 0.4 0.5 -1.6 -0.6 -0.4 0.7 -1.2 -0.7
Number of children fathered 1.6 1.8 4.7 1.4 0.4 0.9 2.2 -0.6 -2.1 -0.9 1.1
Reason for reducing amount of alcohol drunk: Health precaution 0.3 0.3 0.6 0.6 0.8 -0.4 0.7 -0.4 0.7 -0.3 -0.3
Age at first live birth 0.3 0.6 3.0 0.4 -0.3 1.7 0.5 -0.8 -0.5 0.6 -0.1
Pulse wave peak to peak time 0.8 0.9 3.6 1.6 0.1 -0.8 -1.9 -0.4 -0.3 -0.1 0.1
Health satisfaction 0.7 0.9 2.7 -1.6 -1.0 -0.5 -0.5 0.8 0.2 1.0 -1.3
Shortness of breath walking on level ground 0.3 0.4 2.9 0.2 -0.1 0.2 1.7 0.1 0.0 -0.0 -0.5
Qualifications: College or University degree 0.3 1.1 4.7 -0.5 0.8 -0.4 -1.2 0.0 2.2 1.0 0.4
Eye problems/disorders: None of the above 0.9 1.1 2.9 -1.1 0.6 -1.4 1.4 0.1 0.4 -0.0 1.7
Mouth/teeth dental problems: Loose teeth 1.0 1.2 4.2 2.0 -1.2 1.4 1.1 0.5 -0.9 0.2 -0.5
Emphysema/chronic bronchitis 0.3 0.4 1.7 -1.3 -0.9 0.4 0.1 0.3 0.3 0.1 -0.2
Medication for pain relief, constipation, heartburn 0.5 0.8 3.4 1.4 0.4 1.8 0.0 -0.8 0.4 -0.2 -0.1
Neck or shoulder pain in last month 1.1 1.6 5.2 -1.1 0.8 -1.3 -1.7 -2.3 -0.6 -0.7 -0.0
Medication: Blood pressure 1.8 3.2 7.1 1.3 2.3 -1.2 0.5 -2.7 -1.7 -2.6 0.8
Angina (self-reported) 0.5 0.7 3.1 -1.8 0.4 -0.6 -1.1 0.1 -0.4 -0.2 0.8
Migraine (self-reported) 0.4 0.5 1.6 -0.5 -0.4 -1.3 -0.5 0.9 0.1 0.6 -0.5
Medication: Ibuprofen 0.5 0.6 3.3 0.2 0.4 -1.8 0.2 -0.2 -0.2 -0.4 0.9
Medication: Allopurinol 0.6 0.8 2.6 1.4 0.4 1.1 1.6 0.2 -0.3 -0.5 -0.2
Medication: Omeprazole 0.2 0.2 1.1 -0.6 -0.1 0.4 0.0 -0.3 -0.3 0.0 -1.1
Medication: Seretide 50 evohaler 0.8 0.9 3.0 -1.0 -0.7 -0.7 -0.2 -0.2 1.7 0.6 -1.3
Mean time to correctly identify matches 0.6 1.1 3.3 0.5 -0.9 0.8 1.2 1.5 -0.2 0.0 -1.8
Heart disease (mother) 0.4 0.5 1.3 -0.8 0.1 -0.7 1.1 1.0 -0.9 -0.2 0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria 1.1 1.3 3.5 -0.6 1.0 -1.7 -1.9 -1.1 0.2 1.1 -0.6
Whole body fat mass 1.4 5.9 17.8 2.2 3.5 0.8 1.2 -2.4 -1.4 -4.2 1.7
Leg fat mass (right) 1.6 6.1 17.9 1.6 3.6 0.8 0.7 -2.9 -1.2 -4.2 2.0
Arm predicted mass (right) 0.4 2.0 8.4 0.4 1.2 2.9 0.3 -1.6 -0.3 -1.6 0.5
Pulse rate, automated reading 0.6 1.9 7.1 1.2 1.6 1.1 -0.4 -2.7 0.4 -1.3 1.0
Alcohol intake frequency. 0.1 0.3 0.4 -0.6 0.7 -0.7 -0.6 0.4 -0.5 -0.3 0.2
Comparative height size at age 10 0.8 4.3 10.6 -0.6 -3.2 1.4 -0.9 2.0 2.1 1.9 -2.9
Number of full sisters 0.6 0.7 2.3 0.4 -0.8 0.5 -0.3 -0.5 1.5 0.8 -1.1
Suffer from ‘nerves’ 1.3 2.0 6.2 -1.5 -1.9 0.2 0.0 1.3 1.5 2.5 -0.6
Overall health rating 0.2 0.3 1.1 -0.4 0.7 0.1 0.3 -0.4 -1.0 -0.7 0.6
Chest pain or discomfort 0.2 0.2 0.6 -0.8 -0.3 -0.6 0.1 0.2 0.7 0.4 -0.3
Had major operations 2.1 2.5 6.0 1.2 2.0 0.7 -0.1 -1.8 -0.7 -2.0 2.5
Age at last live birth 0.7 0.9 2.4 -0.4 -0.7 1.5 -0.1 -1.5 -0.1 1.2 -0.9
Family relationship satisfaction 0.7 0.9 2.1 -0.2 -0.7 1.0 -0.0 1.4 0.4 1.4 -1.2
Leg pain on walking 1.6 2.0 6.1 -1.7 -1.1 -2.0 -2.5 -0.2 0.6 0.8 -0.7
Qualifications: NVQ or HND or HNC or equivalent 1.1 1.3 4.3 0.0 -1.8 -0.4 -0.6 0.6 0.9 1.1 -2.1
Commuting to job workplace: Car/motor vehicle 0.5 0.6 1.6 0.1 0.7 0.1 1.3 0.6 -0.7 -1.1 0.7
Illness, injury, bereavement, stress in last 2 years 1.5 1.8 3.2 0.6 -1.6 -0.2 -1.3 1.2 1.6 1.8 -1.6
Medication: Aspirin 0.5 0.6 2.1 -1.1 -0.2 -1.4 -0.3 1.2 -0.4 0.2 0.4
Supplements: Vitamin C 0.1 0.2 0.4 0.4 0.5 -0.2 0.7 -0.2 -0.5 -0.4 0.1
Knee pain experienced in last month 0.4 0.7 2.3 -1.5 -1.2 0.6 -0.5 0.3 0.5 0.4 -0.8
Hypertension (Self-reported) 1.2 3.4 13.8 -1.3 2.0 -3.7 -1.3 -1.2 1.7 -1.1 0.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.7 0.8 4.0 -1.2 0.3 -0.2 0.6 2.0 0.5 0.2 0.2
Illnesses of father: Heart disease 0.2 0.3 0.6 -0.8 0.4 -0.8 0.1 0.6 -0.6 -0.1 0.7
Illnesses of siblings: Diabetes 0.2 0.2 0.6 -0.8 -0.4 0.4 0.2 0.5 -0.4 0.6 -0.2
Smoking status: Previous 0.9 1.4 7.2 0.3 0.8 -0.6 1.0 0.1 -2.7 -1.1 0.4
Forced expiratory volume in 1-second (FEV1), predicted 0.6 1.2 2.3 0.1 -1.5 1.1 0.2 0.8 1.4 1.5 -1.0
Whole body fat-free mass 0.2 1.2 6.6 0.0 0.6 2.6 0.3 -1.1 0.4 -1.1 0.1
Leg fat-free mass (right) 0.3 1.3 4.5 0.1 1.1 2.1 0.6 -1.2 0.3 -1.7 0.5
Arm fat percentage (left) 1.7 6.6 19.2 1.5 4.2 -0.7 0.8 -2.5 -1.3 -4.4 2.3
Average weekly red wine intake 0.8 1.2 2.2 0.5 -1.4 -1.4 0.2 -0.5 1.5 1.4 -1.1
Handedness (chirality/laterality): Left-handed 1.3 1.5 4.2 1.4 0.9 0.4 2.0 -0.4 -1.2 -1.5 1.2
Mood swings 1.9 3.4 6.2 -1.9 -2.5 -1.5 -0.8 1.5 1.9 2.5 -1.6
Loneliness, isolation 0.6 0.9 2.9 -0.7 -1.1 -0.1 -0.5 -0.1 1.7 1.3 -0.6
Long-standing illness, disability or infirmity 0.9 1.4 3.0 -1.7 1.7 -1.6 -0.8 -0.5 -0.6 -0.4 1.3
Ever had bowel cancer screening 0.1 0.2 0.5 -0.2 0.4 0.5 0.7 -0.4 -0.2 -0.3 0.4
Diabetes diagnosed by doctor 1.1 1.8 3.5 1.4 1.9 -0.2 0.9 -1.4 -1.5 -1.6 1.3
Ever had stillbirth, spontaneous miscarriage or termination 0.5 0.5 2.0 -1.0 0.0 -0.3 -0.8 -0.4 1.4 0.1 -0.1
Friendships satisfaction 0.5 0.6 1.1 -0.5 -0.6 0.8 -0.8 0.7 0.7 1.1 -1.1
Qualifications: nursing, teaching 0.3 0.5 1.8 0.7 -0.1 -1.4 -0.5 -0.4 0.5 0.8 0.3
Commuting to job workplace: Walk 0.4 0.4 1.6 -0.6 0.2 -1.3 -0.4 -0.1 0.3 0.7 0.9
Eye problems/disorders: Cataract 0.7 0.8 3.9 0.0 -0.1 0.5 -2.0 0.3 0.7 0.7 -1.1
Mouth/teeth dental problems: Mouth ulcers 1.1 1.8 6.4 -2.5 -1.1 -0.7 -1.6 1.2 -0.6 1.2 -0.3
Medication for cholesterol 1.7 2.6 8.1 0.3 -2.8 1.0 0.4 1.0 -0.4 2.1 -2.3
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.3 0.3 1.3 0.8 -0.4 -0.2 1.1 0.4 -0.5 -0.4 0.3
Back pain experienced in last month 2.1 3.0 6.9 -2.1 -1.7 -1.0 -2.6 1.9 0.7 1.5 -1.6
Mineral and other dietary supplements 0.4 0.5 1.1 0.6 1.0 0.0 0.9 -0.6 -0.5 -1.0 0.7
Breast cancer (self-reported) 1.4 1.7 5.9 -0.2 -1.0 -0.3 -0.4 0.2 2.4 0.9 -2.3
Asthma (self-reported) 0.5 1.0 5.1 0.7 0.3 -2.3 0.3 -0.3 1.1 0.1 -0.8
Osteoporosis (self-reported) 0.9 1.1 4.3 -1.4 -0.4 0.4 -2.1 0.3 0.7 0.9 -0.9
Osteoarthritis (self-reported) 0.3 0.4 1.9 0.6 -0.8 1.4 0.1 0.4 0.0 0.1 -0.1
Medication: Aspirin 0.6 0.8 2.5 -1.1 -0.5 -1.6 -0.5 1.4 -0.0 0.5 0.2
Medication: Gliclazide 0.6 0.6 1.4 -0.8 0.7 -0.0 -1.1 0.4 -0.9 -0.5 1.2
Illnesses of father: None of the above (group 1) 0.1 0.1 0.5 0.7 -0.1 0.7 0.1 -0.1 0.1 -0.2 -0.4
Smoking status: Current 1.6 2.5 5.2 -1.6 -2.3 -0.2 -1.5 0.7 1.4 1.8 -2.0
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.8 1.7 3.9 -0.8 -0.1 -0.6 -2.0 -1.4 1.8 1.4 -1.1
Whole body water mass 0.2 1.2 6.3 -0.0 0.6 2.5 0.3 -1.1 0.4 -1.1 0.1
Leg predicted mass (right) 0.2 1.3 4.7 0.1 1.0 2.2 0.6 -1.1 0.4 -1.6 0.4
Arm fat mass (left) 1.2 4.7 14.6 1.3 3.3 0.3 0.9 -2.4 -0.9 -3.8 1.7
Number of self-reported non-cancer illnesses 0.3 0.5 1.3 -0.2 -0.1 -1.1 -0.8 1.2 0.6 0.2 -0.4
Average weekly champagne plus white wine intake 0.2 0.3 1.4 0.4 0.2 0.7 -0.2 0.4 1.2 -0.2 -0.3
Miserableness 3.4 5.9 13.3 -2.2 -3.6 -0.8 -1.1 2.0 2.4 3.7 -2.0
Guilty feelings 0.4 0.6 1.5 -0.5 0.1 -1.1 -0.2 1.2 1.1 0.6 0.5
Wears glasses or contact lenses 0.9 1.1 5.2 -1.1 -0.2 0.3 0.2 2.3 -0.8 -0.6 0.9
Ever taken oral contraceptive pill 0.4 0.4 1.7 -0.3 0.1 -1.3 -1.1 -0.4 0.1 -0.4 0.0
Hearing aid user 0.8 0.9 5.1 -0.5 1.2 -2.3 -0.5 0.0 -0.3 -0.4 0.4
Mother’s age at death 0.4 0.5 1.6 -0.4 -0.5 -0.1 -1.1 0.1 -0.4 1.3 -0.9
Financial situation satisfaction 0.2 0.3 0.9 -1.0 -0.5 -0.8 -0.4 0.1 0.2 0.5 -0.4
Tinnitus: Yes, now most or all of the time 0.6 0.7 1.9 -0.9 -0.1 -1.1 -0.6 0.1 1.4 0.6 -0.7
Commuting to job workplace: Public transport 1.3 1.5 3.7 -0.9 -1.0 -0.2 -1.2 1.2 1.9 1.1 -1.6
Eye problems/disorders: Glaucoma 1.0 1.2 3.7 -0.8 -0.8 -0.1 -1.0 0.2 1.9 1.0 -1.6
Medication: Blood pressure 0.9 1.7 6.2 -1.6 1.5 -2.5 -0.3 0.1 1.1 -0.8 1.0
Pain type(s) experienced in last month: Hip pain 1.2 1.5 2.6 -1.3 -1.2 -0.3 -1.6 0.6 1.3 1.4 -1.5
Supplements: Fish oil (including cod liver oil) 0.3 0.5 2.4 -0.1 -0.5 -0.8 0.0 1.5 -0.0 0.6 0.1
High cholesterol (Self-reported) 0.9 1.7 5.2 -0.2 2.3 0.7 -0.2 -0.6 0.1 -1.8 2.0
Medication: Bendroflumethiazide 0.8 1.2 8.7 0.1 -0.4 -2.9 -0.4 0.6 -0.0 -0.3 -0.2
Medication: Paracetamol 1.4 2.2 6.3 -2.4 -0.1 -2.5 -1.3 -0.1 1.6 0.9 -0.8
Medication: Lisinopril 0.8 1.1 4.9 0.9 1.2 -0.4 -0.2 -0.7 -0.3 -2.2 0.8
Medication: Atorvastatin 0.2 0.2 0.6 0.2 0.8 -0.5 -0.3 0.4 0.8 -0.3 -0.1
Illnesses of father: High blood pressure 1.1 1.4 4.5 -2.1 -0.5 -1.9 -0.1 -0.7 0.5 0.7 -1.2
Alcohol drinker status: Never 0.7 0.8 2.6 -1.4 0.1 -0.3 -0.4 1.0 1.6 0.8 0.2
Ever smoked 0.3 0.5 1.5 -0.6 -1.2 -0.1 0.6 0.6 -1.2 0.2 -0.7
Basal metabolic rate 0.3 1.5 5.7 0.3 1.1 2.4 0.5 -1.4 0.3 -1.6 0.3
Leg fat percentage (left) 1.7 6.0 16.6 1.7 3.6 0.0 0.8 -2.7 -1.8 -4.1 2.0
Arm fat-free mass (left) 0.3 1.7 7.2 0.6 0.8 2.7 0.5 -1.9 -0.3 -1.4 0.0
Number of operations (self-reported) 0.5 0.7 2.3 -0.4 0.7 0.7 -1.4 -0.4 1.5 0.2 -0.1
Average weekly beer plus cider intake 0.5 0.8 2.2 1.0 0.7 1.5 0.9 -0.4 -0.7 -0.8 0.5
Irritability 1.4 2.4 3.5 -1.4 -1.9 -1.0 -1.3 1.4 1.6 1.8 -1.7
Risk taking 0.8 1.1 5.7 0.8 -0.6 0.5 2.4 0.1 -0.6 -1.2 -0.1
Ever had prostate specific antigen (PSA) test 0.4 0.5 1.6 1.0 0.5 -1.3 0.2 0.0 -0.6 -0.2 0.7
Fractured/broken bones in last 5 years 0.6 0.8 3.1 -0.7 -0.3 1.0 -0.7 0.6 -1.8 -0.2 0.9
Age started oral contraceptive pill 0.9 1.1 2.7 0.4 -1.6 0.1 -0.6 0.9 0.9 1.3 -1.5
Diastolic blood pressure, automated reading 0.9 2.8 11.8 -2.4 -0.6 -1.1 -1.2 0.1 3.4 0.6 -1.4
Ever depressed for a whole week 0.6 0.7 1.4 -0.9 -0.3 -1.0 -0.9 0.3 1.2 1.1 -0.5
Unable to work because of sickness or disability 0.3 0.4 1.5 -1.0 0.6 -0.5 -1.2 0.0 0.1 -0.6 -0.1
Commuting to job workplace: Cycle 1.8 2.2 5.6 -0.4 -2.4 -0.3 -1.4 0.5 1.5 1.9 -1.9
Myopia 0.4 0.6 3.0 -0.3 -0.4 -0.7 1.7 0.2 0.9 -0.0 -0.7
Vascular/heart problems diagnosed by doctor 1.4 3.8 13.4 2.4 -1.9 3.7 1.8 1.1 -1.2 1.1 -0.9
Cholesterol lowering medication 0.4 0.6 1.7 -1.3 0.9 -0.3 -0.9 0.4 0.9 -0.1 0.5
Medication: Omeprazole (e.g. Zanprol) 0.3 0.3 0.9 -0.3 0.2 -0.2 0.4 -0.7 -1.0 -0.6 -0.6
Pain experienced in last month 3.0 5.0 11.4 3.4 1.8 1.8 3.1 -0.3 -1.5 -1.8 2.5
Supplements: Calcium 6.3 6.9 19.8 -0.8 -3.4 -0.2 -1.1 2.4 2.4 3.3 -4.5
Basal cell carcinoma (self-reported) 3.5 4.1 7.7 2.7 2.3 -0.9 1.1 -2.8 -1.7 -2.5 1.2
Heart attack/myocardial infarction (self-reported) 0.2 0.3 1.8 1.3 -0.2 0.0 0.3 -0.0 -0.3 -0.5 0.6
Deep venous thrombosis (DVT) (self-reported) 1.0 1.3 4.0 0.4 0.8 1.2 0.7 -0.2 -1.3 -1.4 2.0
Heart disease (siblings) 1.1 1.4 3.4 1.1 -1.8 -0.8 0.4 1.5 -0.9 0.7 -1.4
Alcohol drinker status: Previous 0.2 0.2 0.5 0.3 0.4 -0.7 0.6 -0.4 -0.3 -0.4 -0.7
Pack years of smoking 1.2 1.8 3.9 -0.7 -1.4 -0.0 -0.9 0.8 1.9 1.7 -2.0
Impedance of whole body 0.8 4.2 8.9 1.8 -2.9 -0.4 1.3 1.9 1.0 2.4 -3.0
Leg fat mass (left) 1.5 5.9 17.4 1.6 3.5 1.0 0.8 -2.7 -1.4 -4.2 2.0
Arm predicted mass (left) 0.3 1.5 6.2 0.4 0.8 2.5 0.2 -1.8 -0.2 -1.4 0.1