Hub : Genes

POU6F1

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0700	0.0240	1.1e-04	0.044	0.042	0.027	0.040	0.024	4.1e-06	6.6e-06	2.4e-04	1.1e-05	6.2e-04
2	GTEx	Cells Transformed fibroblasts	0.1830	0.0560	4.7e-04	0.125	NA	0.140	NA	0.152	1.2e-09	NA	1.1e-10	NA	1.7e-11
3	GTEx	Skin Not Sun Exposed Suprapubic	0.1730	0.0660	3.3e-03	0.017	NA	0.017	NA	0.056	3.8e-02	NA	3.6e-02	NA	5.0e-04
4	GTEx	Skin Sun Exposed Lower leg	0.1690	0.0540	2.3e-04	0.023	NA	0.087	NA	0.109	4.8e-03	NA	1.1e-07	NA	2.5e-09
5	METSIM	Adipose	0.0342	0.0145	2.7e-03	0.017	0.013	0.025	0.014	0.017	1.3e-03	3.7e-03	9.6e-05	2.9e-03	1.0e-03
6	NTR	Blood	0.0289	0.0111	2.9e-04	0.012	0.009	0.005	0.009	0.006	6.8e-05	5.9e-04	8.5e-03	5.3e-04	3.5e-03
7	YFS	Blood	0.1248	0.0270	5.6e-17	0.068	0.072	0.092	0.085	0.091	3.6e-21	1.6e-22	1.2e-28	1.8e-26	3.2e-28
8	TCGA	Testicular Germ Cell Tumors	0.2220	0.0940	3.7e-04	0.061	0.093	0.059	NA	0.061	3.5e-03	3.5e-04	3.9e-03	NA	3.5e-03

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8
Bipolar Disorder (2018)	4.1	6.5	14.0	2.6	1.9	-0.2	3.1	-1.7	-3.7	-2.6	2.8
Bipolar Disorder or Schizophrenia	2.4	5.8	13.9	2.8	1.7	-0.8	3.0	-2.3	-3.7	-2.0	1.7
Depressed Affect (Nagel 2018)	2.4	5.0	8.0	-2.4	-2.0	-2.3	-2.6	1.0	2.8	2.6	-1.2
Depression (Nagel 2018)	0.4	0.6	1.8	0.8	0.5	-0.7	-0.5	-0.6	-0.6	-1.3	0.7
Intelligence (Savage-Jansen 2018)	0.5	1.4	6.7	-0.8	1.0	-0.3	-1.0	-1.2	2.6	-0.7	0.3
Neuroticism (Nagel 2018)	2.5	5.9	9.5	-3.1	-1.9	-2.7	-2.5	1.7	2.7	2.9	-1.2
Schizophrenia (2018)	0.6	1.2	3.1	1.6	0.6	-0.7	1.4	-0.8	-1.8	-0.4	-0.2
Schizophrenia vs Biploar Disorder	1.2	1.6	5.4	0.6	-0.6	2.0	0.3	0.5	0.9	1.2	-2.3
Worry (Nagel 2018)	0.5	1.1	2.3	-1.5	-0.6	-1.2	-0.7	1.2	0.7	1.4	0.1
Alzheimer’s Disease (in mother)	0.5	0.6	2.2	0.0	0.7	-0.1	-1.5	-0.6	0.3	-0.0	-1.1
Alzheimer’s Disease (in father)	1.0	1.0	1.9	1.0	-1.4	0.5	0.6	1.2	-0.5	1.2	-1.3
Alzheimer’s Disease (including proxy)	0.5	0.7	3.0	1.0	0.4	-0.2	-1.2	-0.3	0.2	0.3	-1.7
Crohns Disease (2017)	0.7	1.6	5.5	2.3	-0.9	-0.4	-0.0	-1.6	-1.3	-0.0	-1.4
Irritable Bowel Disease (IBD)	0.7	1.6	5.6	1.9	0.2	-1.2	0.6	-1.0	-2.4	-1.0	0.4
Ulcerative Colitis (UC)	1.4	2.6	8.1	0.9	1.2	-1.2	1.1	0.0	-2.8	-1.9	2.0
Major Depression (MDD)	2.0	2.4	4.1	-1.8	-1.5	-0.9	-1.8	1.2	1.2	2.0	-1.7
Reaction Time	0.4	0.7	1.8	0.6	-0.3	0.6	1.3	1.2	-0.3	-0.2	-1.4
Verbal and Numeric Reasoning (VNR)	0.4	1.0	4.8	-0.9	1.3	0.3	-0.4	0.2	2.2	-0.2	0.7
Breast Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Ovarian Cancer	1.0	1.4	3.7	-1.0	1.9	-0.6	-0.4	-0.9	-1.0	-1.4	1.4
Prostate Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Age at First Birth	0.9	1.3	3.1	0.4	0.8	-0.1	1.6	-0.7	-1.8	-0.8	1.7
Bipolar Disorder (2011)	3.3	3.2	7.5	1.2	2.7	-1.2	1.8	-1.2	-1.8	-2.7	0.0
Body Mass Index (BMI) (2010)	1.7	2.4	6.5	0.8	2.5	-0.2	-0.5	-1.5	-0.1	-2.5	1.7
Coronary Artery Disease (CAD)	0.3	0.3	1.0	0.2	0.7	0.8	-0.2	-0.2	1.0	-0.4	0.3
Crohns Disease (2012)	0.5	0.7	2.8	1.1	0.3	-0.3	-1.1	-1.7	-0.6	-0.4	0.1
Mean Putamen Volume	0.3	0.3	1.6	-1.3	-0.4	-0.1	0.5	0.7	-0.1	0.4	-0.1
Fasting Glucose	0.4	0.4	1.2	0.5	0.4	0.6	0.8	0.6	-0.6	-0.2	1.1
HbA1C	0.5	0.6	2.0	-0.4	0.1	-0.6	0.0	1.4	-1.2	-0.5	0.6
HDL Cholesterol	0.8	1.3	2.8	-0.5	-1.5	1.3	-0.5	0.8	1.2	1.0	-1.7
LDL Cholesterol	1.8	2.8	5.4	-1.4	-2.2	-0.5	-2.3	1.9	1.5	1.7	-1.1
Lupus	0.5	0.8	1.5	0.9	-1.0	-0.6	-0.1	1.2	0.7	1.1	-1.1
Neuroticism (2016)	3.0	4.4	7.8	-2.8	-1.8	-2.3	-0.9	1.3	2.6	2.8	-1.5
Primary Biliary Cirrhosis	0.8	1.1	2.6	1.3	1.6	-1.1	0.3	-1.2	-0.2	-1.2	0.2
Rheumatoid Arthritis	1.4	1.9	4.5	0.0	-2.1	-0.6	0.3	1.3	1.1	1.7	-2.0
Schizophrenia (2014)	1.3	2.8	7.0	2.6	0.9	0.1	2.2	-1.4	-2.3	-1.4	0.6
Triglycerides	0.3	0.4	1.3	0.2	0.8	-0.2	-1.2	-0.0	0.0	-0.9	0.8
Type 2 Diabetes (T2D) (2012)	0.4	0.4	1.5	0.2	0.9	-1.2	-0.6	0.1	0.3	-0.5	0.5
Ulcerative Colitis	1.4	2.1	6.0	-0.5	1.4	-0.9	0.7	-0.1	-2.1	-1.6	2.5
Blood Eosinophil Count	0.3	2.3	5.2	2.2	1.8	0.2	1.4	-1.1	-0.8	-2.3	1.0
Blood Platelet Count	3.5	40.4	118.8	7.7	0.9	7.0	10.9	0.0	-7.5	-4.1	4.7
Blood Red Count	0.1	1.1	4.5	-0.0	1.1	0.5	-1.3	-1.1	-2.1	-0.7	-0.1
Blood White Count	0.5	3.9	13.1	2.8	1.0	0.6	3.6	-0.8	-1.8	-2.0	1.0
Heel T-Score	0.5	4.3	16.4	0.9	-1.9	-0.6	0.2	0.6	2.5	2.5	-4.0
BMI	1.8	10.3	25.5	0.6	5.0	-0.1	0.3	-4.2	-1.6	-4.7	3.7
Height	0.6	12.1	30.6	1.2	-5.5	3.6	1.0	2.7	2.8	3.6	-4.9
Waist Hip Ratio (WHR)	0.2	0.7	2.1	-0.1	1.1	0.9	0.1	0.3	-0.5	-1.2	1.5
Systolic Blood Pressure	0.6	3.0	9.1	-2.3	-0.7	-2.2	-0.9	0.3	3.0	1.2	-1.3
Smoking Status	0.5	1.2	3.8	-0.3	-1.5	-0.1	0.4	2.0	-1.0	1.0	-1.2
Allergy or Eczema	0.7	1.9	4.4	-0.2	-1.0	-1.9	-0.7	0.2	1.8	2.1	-1.4
Cardiovascular Disease	1.4	4.6	10.9	-2.4	2.5	-3.3	-2.1	-1.1	2.1	-1.3	1.5
Hypothyroidism (self reported)	0.3	0.6	1.4	0.2	-0.1	-0.2	-1.1	0.1	1.2	0.9	-1.2
Respiratory disease	0.4	0.8	3.8	0.5	1.0	-1.9	1.0	-0.4	-0.2	-0.7	0.2
Type 2 Diabetes (T2D) (2018)	0.4	0.8	2.6	0.3	1.6	0.2	0.6	-1.0	-0.4	-0.8	1.2
Lung FEV1/FVC ratio	0.4	1.8	6.3	-1.7	-0.0	1.2	-2.5	-0.2	1.8	0.7	-0.1
Lung FVC	0.8	3.9	13.0	-3.6	-0.9	-1.8	-2.3	-0.5	1.9	1.8	-1.3
Neuroticism	2.4	5.8	11.9	-3.3	-2.1	-1.8	-1.6	2.1	2.7	3.5	-1.2
Chronotype (morning person)	0.8	1.9	5.7	1.0	2.2	0.6	0.7	-1.2	0.0	-1.2	2.4
Hair Pigment	0.0	1.0	4.6	-1.3	-0.4	0.9	-0.6	2.1	0.4	0.4	0.2
Tanning	0.2	3.0	7.5	-0.4	2.7	1.0	0.7	-1.3	-1.8	-1.7	2.6
Hand grip strength (left)	1.0	2.5	5.7	-0.5	-2.1	1.8	-1.1	0.5	2.0	2.4	-1.0
Number of treatments/medications taken	1.0	1.7	7.7	-1.6	1.4	-2.8	-0.5	0.0	-0.2	-0.8	0.9
Average weekly spirits intake	0.6	0.8	2.3	-1.5	-0.6	-0.7	-1.4	0.5	0.6	0.4	0.6
Sensitivity / hurt feelings	0.5	0.9	2.0	-1.1	-0.3	-0.9	-0.4	0.8	1.4	1.4	-0.7
Frequency of depressed mood in last 2 weeks	0.3	0.5	1.1	0.8	0.2	-0.2	0.2	-0.7	-1.0	-1.0	0.6
Hearing difficulty/problems: Yes	1.2	1.8	6.8	-1.5	-0.3	-2.6	0.1	1.3	1.3	0.9	-1.0
Relative age of first facial hair	0.7	1.5	6.6	-1.5	-0.6	-2.6	-0.9	-0.0	-0.7	1.1	-0.3
Other serious medical condition/disability diagnosed by doctor	1.1	1.4	4.1	-2.0	1.3	-0.4	-1.6	-0.5	-0.4	-1.2	0.8
Ever used hormone-replacement therapy (HRT)	2.5	3.2	5.8	1.2	1.9	0.8	1.7	-1.5	-2.2	-2.4	2.0
Ever had hysterectomy (womb removed)	2.7	3.0	10.0	-0.8	-1.1	-1.9	-3.2	-0.3	1.9	1.6	-1.6
Systolic blood pressure, automated reading	1.4	4.1	12.3	-2.4	-1.4	-1.2	-1.0	1.4	3.5	2.1	-1.8
Eye problems/disorders: Diabetes related eye disease	2.0	2.2	8.2	2.9	0.7	2.2	0.8	0.0	-1.0	-1.6	-0.6
Angina	0.4	0.6	1.5	-1.2	0.4	-0.5	-0.9	0.0	-0.7	-0.5	1.0
Medication for hormone replacement therapy	1.3	1.5	4.8	-0.2	2.2	-0.4	0.5	-1.4	-0.7	-1.7	1.3
Vitamin and mineral supplements	0.2	0.3	0.9	-0.6	-0.3	-0.4	-0.6	1.0	-0.4	0.4	-0.0
Supplements: Zinc	0.3	0.3	1.1	1.1	-0.4	0.8	-0.3	-0.2	0.2	0.3	-0.8
Medication: Co-codamol	1.6	1.9	3.5	0.9	1.3	1.2	0.8	-1.4	-1.9	-1.8	1.5
Medication: Metformin	0.4	0.6	2.0	1.4	0.8	-0.3	0.6	-0.4	-0.5	-0.9	0.3
Diabetes (father)	0.8	0.9	3.8	-1.9	-0.4	0.4	-0.8	0.4	1.3	0.9	-0.3
Diabetes (mother)	0.5	0.6	1.1	-0.5	0.7	-0.4	0.5	-0.8	-1.0	-1.0	0.8
Severe depression (siblings)	0.3	0.3	0.7	-0.6	-0.2	-0.1	0.4	0.8	-0.8	-0.4	0.6
Pack years adult smoking proportion	1.1	1.6	3.9	-0.5	-1.4	0.1	-0.8	0.6	1.9	1.6	-2.0
Impedance of leg (right)	0.7	3.2	7.8	1.3	-2.8	-0.4	0.6	1.5	0.5	2.5	-2.6
Leg fat-free mass (left)	0.3	1.4	3.6	0.2	1.4	1.8	0.5	-1.3	0.2	-1.9	0.6
Trunk fat percentage	1.3	5.3	16.5	2.1	3.4	-0.4	1.2	-2.1	-1.5	-4.1	1.4
Hand grip strength (right)	0.8	2.2	6.6	0.2	-2.0	1.4	-0.7	0.2	1.7	2.6	-1.4
Townsend deprivation index at recruitment	0.3	0.4	1.8	-0.0	-0.5	-0.2	0.7	-0.3	0.2	0.3	-1.3
Current tobacco smoking	0.9	1.5	2.9	-1.2	-1.5	-0.3	-1.7	0.1	1.3	1.2	-1.6
Average weekly fortified wine intake	0.4	0.5	2.5	-0.3	-0.4	-0.3	0.3	1.6	-0.6	0.4	0.6
Maternal smoking around birth	0.6	0.9	4.4	-0.3	-1.3	0.0	0.2	-0.1	0.1	0.8	-2.1
Fed-up feelings	0.2	0.3	1.0	-0.2	0.4	-0.2	-1.0	0.2	0.5	0.2	0.8
Frequency of unenthusiasm / disinterest in last 2 weeks	0.8	1.0	3.2	1.8	0.7	0.1	0.8	-0.8	-1.0	-1.3	0.6
Relative age voice broke	0.5	0.7	2.7	-0.4	-1.0	-0.2	-1.6	-0.8	0.1	0.7	-0.8
Taking other prescription medications	1.2	1.8	6.2	-2.5	-0.8	-1.0	-1.2	1.3	1.0	1.1	-1.3
Age when periods started (menarche)	1.6	3.8	8.4	0.5	-2.9	1.2	1.7	2.4	0.6	2.0	-2.8
Bilateral oophorectomy (both ovaries removed)	2.4	2.8	5.6	1.8	2.3	-0.2	0.8	-2.4	-0.7	-2.2	1.6
Heel bone mineral density (BMD) T-score, automated (left)	0.4	1.0	4.4	0.0	-0.5	0.0	-0.1	0.7	2.1	0.7	-1.5
Tinnitus: Yes, but not now, but have in the past	0.8	0.9	1.6	0.9	1.0	1.2	-0.5	-1.0	-0.0	-1.3	0.8
Qualifications: CSEs or equivalent	1.4	1.8	7.2	0.8	1.5	-0.1	1.4	-0.0	-2.7	-1.5	0.7
Serious illness, injury or assault to yourself	1.0	1.2	2.6	-1.6	1.0	0.3	0.5	-1.6	-0.8	-1.2	0.8
High blood pressure	1.5	4.2	13.9	-2.0	2.5	-3.7	-1.6	-1.6	1.3	-1.4	1.0
Hayfever, allergic rhinitis or eczema	0.9	2.0	5.0	0.8	-1.4	-1.3	0.3	0.6	1.8	2.2	-1.7
Multivitamins +/- minerals	0.5	0.6	2.0	0.9	-0.2	0.1	-0.3	-1.4	1.0	0.0	-0.9
Stomach or abdominal pain in last month	0.3	0.4	1.2	-0.3	0.6	-0.9	-0.7	-1.1	0.6	-0.3	-0.3
Supplements: Glucosamine	0.8	1.0	2.8	-0.6	-1.7	1.0	0.2	0.6	0.6	1.5	-1.0
Diverticular disease/diverticulitis (self-reported)	0.1	0.2	0.3	0.5	-0.4	-0.5	-0.1	0.5	-0.6	-0.2	-0.2
Medication: Atenolol	1.2	1.5	3.9	-0.1	1.5	-0.2	0.4	-1.1	-1.3	-2.0	1.5
Medication: Levothyroxine sodium	0.6	1.1	3.0	0.6	-0.5	-1.4	-0.8	0.9	1.7	0.7	-1.1
Sitting height	0.2	1.2	3.6	-0.7	-0.8	1.9	0.4	0.4	1.7	0.5	-1.1
Chronic bronchitis/emphysema (father)	1.2	1.4	3.3	0.5	1.8	-0.9	0.4	-0.4	-1.2	-1.2	1.8
High blood pressure (mother)	0.6	0.9	2.9	-0.9	1.0	0.6	-0.9	-0.1	0.0	-1.2	1.7
Body mass index (BMI)	2.0	8.7	23.1	0.7	4.8	-0.2	0.2	-3.2	-1.7	-4.8	3.1
Impedance of leg (left)	0.7	3.3	8.8	1.4	-3.0	0.3	0.9	1.3	0.2	2.3	-2.7
Leg predicted mass (left)	0.3	1.4	3.6	0.1	1.4	1.9	0.5	-1.2	0.3	-1.9	0.6
Trunk fat mass	1.2	5.2	16.1	2.2	3.3	0.5	1.3	-2.2	-1.2	-4.0	1.4
Waist circumference	1.4	5.1	16.0	1.2	3.1	1.0	0.5	-2.5	-1.2	-4.0	2.2
Number of incorrect matches in round	0.8	1.4	3.3	0.7	-1.6	0.4	1.2	1.8	-0.9	0.8	-1.2
Past tobacco smoking	0.5	0.9	3.1	0.7	1.3	0.5	-0.6	-0.8	1.8	-0.3	0.9
Alcohol usually taken with meals	0.1	0.1	0.2	0.4	0.3	-0.3	0.2	-0.5	0.2	-0.0	0.3
Nervous feelings	0.3	0.6	2.3	-1.5	0.3	-1.1	0.3	0.1	-0.3	0.5	0.7
Frequency of tenseness / restlessness in last 2 weeks	0.2	0.3	1.7	-0.6	-0.0	-1.3	0.2	-0.0	0.3	-0.4	0.2
Hearing difficulty/problems with background noise	0.6	1.0	2.4	-1.5	-0.2	-0.5	0.6	0.7	1.6	1.2	-1.0
Hair/balding pattern: Pattern 2	0.6	0.8	2.2	-0.3	0.9	0.3	0.5	-0.4	-1.3	-0.8	1.5
Had menopause	1.1	1.3	4.6	-0.7	-1.5	2.1	-0.5	1.6	-0.1	0.6	-0.4
Had other major operations	1.0	1.2	4.1	-0.2	-0.5	-0.4	-2.0	-0.3	1.1	1.5	-1.3
Forced vital capacity (FVC)	1.2	4.7	10.9	-1.2	-2.4	0.7	-1.4	-0.5	3.3	3.0	-2.8
Heel bone mineral density (BMD) T-score, automated (right)	0.6	1.3	4.5	1.7	-0.2	0.3	0.4	0.7	2.1	0.2	-1.6
Ever unenthusiastic/disinterested for a whole week	1.1	1.4	3.1	-1.8	-0.7	-1.0	-0.6	1.1	1.7	1.4	0.2
Qualifications: None of the above	0.5	1.1	3.3	-1.5	-1.0	-0.7	-0.2	1.0	-1.8	0.4	-0.5
Financial difficulties in last 2 years	0.3	0.4	1.6	-0.8	-0.7	-0.4	-0.0	0.1	0.6	0.5	-1.3
Mouth/teeth dental problems	0.8	1.3	4.3	1.5	1.2	0.2	0.5	-2.1	0.9	-1.0	0.5
Heart attack	0.4	0.5	2.7	1.6	-0.2	0.3	0.6	0.2	-0.2	-0.5	0.5
Allergy	0.6	1.4	3.1	-0.8	1.0	1.8	-1.1	-0.8	-1.0	-1.6	1.0
Pain all over the body in last month	0.8	0.8	2.4	0.3	0.4	-0.4	1.1	-0.8	-1.5	-1.2	0.8
Diabetes (self-reported)	1.2	1.8	3.1	1.5	1.8	0.3	0.6	-1.3	-1.7	-1.4	1.5
Hayfever/allergic rhinitis (self-reported)	0.5	0.7	2.6	1.3	-0.6	0.4	0.3	-0.3	1.6	0.2	-0.3
Medication: Ramipril	3.4	4.4	7.8	-0.1	2.3	-1.0	1.3	-2.8	-2.4	-2.6	2.5
Medication: Simvastatin	0.3	0.5	1.5	-0.8	0.6	0.3	-0.3	-0.1	-0.7	-0.9	1.2
Fluid intelligence score	0.3	0.7	4.4	0.4	0.8	0.1	-0.7	-0.0	2.1	-0.1	-0.3
Illnesses of siblings	0.2	0.3	1.4	-0.6	-0.3	1.2	-0.0	0.0	0.6	0.2	-0.3
Neuroticism score	1.8	3.7	9.4	-2.2	-2.1	-0.5	-0.3	2.4	1.7	3.1	-1.2
Weight	0.6	3.0	9.0	1.1	2.3	1.5	0.7	-2.1	-0.4	-3.0	1.0
Impedance of arm (right)	0.9	4.1	7.9	1.4	-2.8	-1.2	1.5	2.2	1.6	2.3	-2.5
Arm fat percentage (right)	1.6	6.2	18.1	1.3	4.0	-1.2	0.6	-2.5	-1.1	-4.3	2.1
Trunk fat-free mass	0.2	1.2	8.3	-0.2	0.1	2.9	0.2	-0.8	0.7	-0.5	-0.2
Hip circumference	0.8	3.4	10.3	1.5	2.1	1.5	1.3	-2.2	-0.8	-3.2	0.9
Time employed in main current job	0.5	0.6	1.5	-1.0	-0.6	0.7	-0.3	1.2	1.1	0.6	0.1
Alcohol intake versus 10 years previously	0.3	0.4	1.1	-1.1	0.8	-0.3	0.4	-0.4	-0.7	-0.7	0.6
Father’s age at death	0.7	1.0	2.5	1.1	1.6	-0.6	0.4	-0.7	-0.7	-1.5	0.4
Worrier / anxious feelings	0.2	0.5	1.5	0.4	0.1	0.5	1.2	1.0	-0.3	-0.2	0.8
Frequency of tiredness / lethargy in last 2 weeks	0.3	0.5	0.9	-0.4	-0.2	-1.0	-0.8	-0.9	0.4	0.2	-0.9
Falls in the last year	1.3	1.8	3.3	-1.7	0.1	-1.8	-1.5	-1.8	0.6	-0.3	-1.5
Hair/balding pattern: Pattern 3	1.4	2.0	5.4	0.0	-2.3	-0.3	-0.6	1.9	-0.0	1.8	-1.9
Number of live births	0.4	0.6	2.0	0.9	-0.8	0.5	0.6	-0.4	-0.4	0.2	-1.4
Forced expiratory volume in 1-second (FEV1)	1.1	3.7	11.1	-1.3	-1.5	1.5	-1.5	-1.0	3.3	2.4	-1.8
Pulse rate	2.8	4.7	6.7	1.9	2.4	1.5	2.5	-2.5	-1.8	-2.6	1.9
Happiness	0.6	0.7	3.1	0.5	-0.5	1.7	1.0	0.2	-0.7	0.4	-0.7
Noisy workplace	1.0	1.2	3.3	-0.4	1.1	-0.0	1.1	-0.2	-1.8	-1.1	1.5
Qualifications: A levels/AS levels or equivalent	0.2	0.5	2.3	1.1	0.5	0.5	-0.2	-0.3	1.5	0.3	-0.0
Serious illness, injury or assault of a close relative in last 2 years	1.8	2.1	8.2	-1.0	1.5	0.0	1.4	-0.4	-1.1	-1.4	2.9
Mouth/teeth dental problems: Dentures	0.7	1.3	3.0	-1.7	-0.1	-0.8	-1.1	1.5	-1.7	-0.3	0.2
Asthma	0.6	1.1	6.8	0.4	0.5	-2.6	0.4	-0.3	1.1	-0.0	-0.5
Medication: Ibuprofen (e.g. Nurofen)	0.5	0.7	1.6	0.5	0.9	-0.7	0.7	-0.6	-0.4	-1.1	1.3
Medication: Cholesterol lowering	0.3	0.5	1.6	0.0	0.9	0.0	0.0	-0.5	-0.9	-1.3	0.8
Depression (self-reported)	0.9	1.0	3.2	-0.9	-0.7	-0.3	-0.6	0.6	1.8	1.4	-0.9
Medication: Lansoprazole	1.9	2.1	7.0	1.0	2.6	-1.3	0.1	-0.5	-1.0	-1.5	2.0
Prospective memory result	0.8	0.9	4.8	-2.2	-0.6	-0.3	0.1	0.7	-0.9	1.0	0.2
Lung cancer (father)	1.0	1.2	2.2	0.8	0.2	-0.9	1.1	-1.5	-1.4	-1.4	0.9
Illnesses of mother	0.9	1.1	2.7	-0.5	-1.5	0.5	-0.6	0.9	1.4	1.7	-0.6
Forced expiratory volume in 1-second (FEV1), Best measure	1.2	3.8	11.8	-1.4	-1.5	0.5	-2.0	-1.0	3.4	2.5	-1.9
Pulse wave Arterial Stiffness index	1.0	1.2	3.8	-1.6	-0.6	1.1	2.0	0.6	0.5	0.5	-0.7
Impedance of arm (left)	0.8	3.9	6.9	1.3	-2.6	-0.8	1.3	2.4	1.5	2.3	-2.6
Arm fat mass (right)	1.2	5.0	15.6	1.1	3.5	0.1	0.6	-2.6	-0.9	-3.9	1.7
Trunk predicted mass	0.2	1.2	8.3	-0.2	0.1	2.9	0.3	-0.8	0.7	-0.5	-0.1
Standing height	1.1	10.4	23.0	0.9	-4.8	3.8	1.0	2.3	2.9	3.3	-4.4
Length of working week for main job	0.8	0.8	1.9	0.3	0.5	1.1	-0.6	-0.5	-1.1	-1.1	1.4
Exposure to tobacco smoke at home	0.7	0.7	2.1	0.9	-1.1	0.6	-0.9	-0.5	-0.1	0.6	-1.4
Breastfed as a baby	0.9	1.1	4.4	0.0	-0.1	1.5	2.1	1.0	-0.7	-0.3	0.5
Tense / ‘highly strung’	1.0	1.6	3.6	-0.2	-1.5	1.0	1.9	1.4	0.6	1.6	-1.1
Seen doctor (GP) for nerves, anxiety, tension or depression	0.7	1.1	3.7	-0.0	1.9	0.5	1.3	-0.2	-0.8	-0.7	1.5
Hair/balding pattern: Pattern 4	0.3	0.8	2.0	-0.9	-1.0	-0.5	-1.0	1.4	0.2	0.7	0.9
Birth weight of first child	0.3	0.5	1.4	0.6	-0.2	0.3	-0.6	-1.2	1.0	-0.4	-0.7
Peak expiratory flow (PEF)	0.6	1.3	3.6	-1.3	-0.4	1.2	-0.1	-1.0	1.9	1.6	-0.4
Pulse wave reflection index	2.9	3.6	11.0	-3.3	-0.9	-0.7	-1.0	2.1	2.4	1.9	-1.3
Ever highly irritable/argumentative for 2 days	1.7	2.1	3.5	1.8	1.7	1.7	0.3	-0.7	-0.4	-1.9	1.9
Loud music exposure frequency	0.1	0.1	0.2	0.1	0.2	-0.1	0.1	-0.4	0.0	-0.3	0.4
Qualifications: O levels/GCSEs or equivalent	1.2	2.0	6.0	2.5	1.6	1.0	0.5	-1.2	1.2	-1.3	1.1
Mouth/teeth dental problems: Bleeding gums	0.3	0.3	1.1	0.5	-0.3	0.1	1.1	0.9	0.4	0.5	-0.3
Blood clot in the leg (DVT)	1.0	1.3	3.8	0.5	0.7	1.5	0.7	-0.0	-1.2	-1.4	1.9
Medication: Paracetamol	0.6	0.9	3.8	-1.4	0.0	-2.0	-0.5	-0.4	0.9	0.3	-0.7
Headache pain in last month	1.2	2.1	4.5	-2.1	-0.4	-2.1	-2.1	-0.0	1.3	0.9	-1.0
Medication for cholesterol, blood pressure or diabetes	0.9	1.6	3.4	-0.1	-1.4	0.9	-0.5	1.3	1.8	1.8	-1.1
Glaucoma (self-reported)	1.2	1.4	4.5	-0.6	-1.1	-0.1	-0.3	1.0	2.1	1.4	-1.6
Gout (self-reported)	0.5	0.7	1.9	1.2	-0.2	0.5	1.4	0.4	0.5	0.0	-1.2
Hypothyroidism/myxoedema (self-reported)	0.8	1.6	4.6	-0.1	-0.8	-0.4	-1.4	0.9	2.1	1.7	-1.4
Medication: Amlodipine	1.2	1.7	5.1	0.6	1.8	-2.3	-0.8	-0.9	-0.8	-1.6	0.7
Medication: Ventolin 100micrograms inhaler	1.8	2.3	3.8	0.6	2.0	-1.7	-0.9	-1.7	-1.0	-1.6	2.0
Birth weight	0.5	1.2	2.4	0.4	-1.4	1.2	1.2	1.6	-0.1	1.1	-0.9
Chronic bronchitis/emphysema (mother)	1.4	1.6	3.5	-1.1	-1.9	-1.1	1.2	0.9	-0.7	1.6	-1.3
High blood pressure (siblings)	0.4	0.6	3.9	-0.1	0.1	-2.0	-0.2	-0.5	0.6	0.3	-0.3
Forced vital capacity (FVC), Best measure	1.2	4.2	10.2	-1.4	-2.1	-0.0	-1.6	-0.4	3.2	2.9	-2.5
Body fat percentage	1.7	6.8	20.2	2.1	3.8	-0.3	1.0	-2.7	-1.8	-4.5	1.9
Leg fat percentage (right)	1.6	5.8	15.5	1.5	3.8	-0.4	0.5	-2.6	-1.6	-3.9	2.1
Arm fat-free mass (right)	0.4	1.9	9.1	0.2	1.0	3.0	0.5	-1.5	-0.3	-1.5	0.4
Exposure to tobacco smoke outside home	0.2	0.3	0.6	0.3	-0.4	-0.8	-0.3	-0.7	-0.4	0.2	-0.6
Comparative body size at age 10	0.3	1.0	3.0	0.8	1.2	-0.6	-0.5	-0.9	1.7	-0.7	1.0
Number of full brothers	0.7	0.9	2.1	0.7	1.5	0.2	1.0	-0.3	-0.9	-1.3	0.7
Worry too long after embarrassment	4.3	7.3	14.4	-3.6	-3.0	-1.6	-0.6	2.7	2.4	3.8	-2.5
Seen a psychiatrist for nerves, anxiety, tension or depression	0.2	0.3	1.0	-1.0	-0.2	-0.9	-0.6	0.0	0.0	0.5	-0.3
Wheeze or whistling in the chest in last year	0.4	0.7	2.4	0.4	0.5	-1.6	-0.6	-0.4	0.7	-1.2	-0.7
Number of children fathered	1.6	1.8	4.7	1.4	0.4	0.9	2.2	-0.6	-2.1	-0.9	1.1
Reason for reducing amount of alcohol drunk: Health precaution	0.3	0.3	0.6	0.6	0.8	-0.4	0.7	-0.4	0.7	-0.3	-0.3
Age at first live birth	0.3	0.6	3.0	0.4	-0.3	1.7	0.5	-0.8	-0.5	0.6	-0.1
Pulse wave peak to peak time	0.8	0.9	3.6	1.6	0.1	-0.8	-1.9	-0.4	-0.3	-0.1	0.1
Health satisfaction	0.7	0.9	2.7	-1.6	-1.0	-0.5	-0.5	0.8	0.2	1.0	-1.3
Shortness of breath walking on level ground	0.3	0.4	2.9	0.2	-0.1	0.2	1.7	0.1	0.0	-0.0	-0.5
Qualifications: College or University degree	0.3	1.1	4.7	-0.5	0.8	-0.4	-1.2	0.0	2.2	1.0	0.4
Eye problems/disorders: None of the above	0.9	1.1	2.9	-1.1	0.6	-1.4	1.4	0.1	0.4	-0.0	1.7
Mouth/teeth dental problems: Loose teeth	1.0	1.2	4.2	2.0	-1.2	1.4	1.1	0.5	-0.9	0.2	-0.5
Emphysema/chronic bronchitis	0.3	0.4	1.7	-1.3	-0.9	0.4	0.1	0.3	0.3	0.1	-0.2
Medication for pain relief, constipation, heartburn	0.5	0.8	3.4	1.4	0.4	1.8	0.0	-0.8	0.4	-0.2	-0.1
Neck or shoulder pain in last month	1.1	1.6	5.2	-1.1	0.8	-1.3	-1.7	-2.3	-0.6	-0.7	-0.0
Medication: Blood pressure	1.8	3.2	7.1	1.3	2.3	-1.2	0.5	-2.7	-1.7	-2.6	0.8
Angina (self-reported)	0.5	0.7	3.1	-1.8	0.4	-0.6	-1.1	0.1	-0.4	-0.2	0.8
Migraine (self-reported)	0.4	0.5	1.6	-0.5	-0.4	-1.3	-0.5	0.9	0.1	0.6	-0.5
Medication: Ibuprofen	0.5	0.6	3.3	0.2	0.4	-1.8	0.2	-0.2	-0.2	-0.4	0.9
Medication: Allopurinol	0.6	0.8	2.6	1.4	0.4	1.1	1.6	0.2	-0.3	-0.5	-0.2
Medication: Omeprazole	0.2	0.2	1.1	-0.6	-0.1	0.4	0.0	-0.3	-0.3	0.0	-1.1
Medication: Seretide 50 evohaler	0.8	0.9	3.0	-1.0	-0.7	-0.7	-0.2	-0.2	1.7	0.6	-1.3
Mean time to correctly identify matches	0.6	1.1	3.3	0.5	-0.9	0.8	1.2	1.5	-0.2	0.0	-1.8
Heart disease (mother)	0.4	0.5	1.3	-0.8	0.1	-0.7	1.1	1.0	-0.9	-0.2	0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.1	1.3	3.5	-0.6	1.0	-1.7	-1.9	-1.1	0.2	1.1	-0.6
Whole body fat mass	1.4	5.9	17.8	2.2	3.5	0.8	1.2	-2.4	-1.4	-4.2	1.7
Leg fat mass (right)	1.6	6.1	17.9	1.6	3.6	0.8	0.7	-2.9	-1.2	-4.2	2.0
Arm predicted mass (right)	0.4	2.0	8.4	0.4	1.2	2.9	0.3	-1.6	-0.3	-1.6	0.5
Pulse rate, automated reading	0.6	1.9	7.1	1.2	1.6	1.1	-0.4	-2.7	0.4	-1.3	1.0
Alcohol intake frequency.	0.1	0.3	0.4	-0.6	0.7	-0.7	-0.6	0.4	-0.5	-0.3	0.2
Comparative height size at age 10	0.8	4.3	10.6	-0.6	-3.2	1.4	-0.9	2.0	2.1	1.9	-2.9
Number of full sisters	0.6	0.7	2.3	0.4	-0.8	0.5	-0.3	-0.5	1.5	0.8	-1.1
Suffer from ‘nerves’	1.3	2.0	6.2	-1.5	-1.9	0.2	0.0	1.3	1.5	2.5	-0.6
Overall health rating	0.2	0.3	1.1	-0.4	0.7	0.1	0.3	-0.4	-1.0	-0.7	0.6
Chest pain or discomfort	0.2	0.2	0.6	-0.8	-0.3	-0.6	0.1	0.2	0.7	0.4	-0.3
Had major operations	2.1	2.5	6.0	1.2	2.0	0.7	-0.1	-1.8	-0.7	-2.0	2.5
Age at last live birth	0.7	0.9	2.4	-0.4	-0.7	1.5	-0.1	-1.5	-0.1	1.2	-0.9
Family relationship satisfaction	0.7	0.9	2.1	-0.2	-0.7	1.0	-0.0	1.4	0.4	1.4	-1.2
Leg pain on walking	1.6	2.0	6.1	-1.7	-1.1	-2.0	-2.5	-0.2	0.6	0.8	-0.7
Qualifications: NVQ or HND or HNC or equivalent	1.1	1.3	4.3	0.0	-1.8	-0.4	-0.6	0.6	0.9	1.1	-2.1
Commuting to job workplace: Car/motor vehicle	0.5	0.6	1.6	0.1	0.7	0.1	1.3	0.6	-0.7	-1.1	0.7
Illness, injury, bereavement, stress in last 2 years	1.5	1.8	3.2	0.6	-1.6	-0.2	-1.3	1.2	1.6	1.8	-1.6
Medication: Aspirin	0.5	0.6	2.1	-1.1	-0.2	-1.4	-0.3	1.2	-0.4	0.2	0.4
Supplements: Vitamin C	0.1	0.2	0.4	0.4	0.5	-0.2	0.7	-0.2	-0.5	-0.4	0.1
Knee pain experienced in last month	0.4	0.7	2.3	-1.5	-1.2	0.6	-0.5	0.3	0.5	0.4	-0.8
Hypertension (Self-reported)	1.2	3.4	13.8	-1.3	2.0	-3.7	-1.3	-1.2	1.7	-1.1	0.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.7	0.8	4.0	-1.2	0.3	-0.2	0.6	2.0	0.5	0.2	0.2
Illnesses of father: Heart disease	0.2	0.3	0.6	-0.8	0.4	-0.8	0.1	0.6	-0.6	-0.1	0.7
Illnesses of siblings: Diabetes	0.2	0.2	0.6	-0.8	-0.4	0.4	0.2	0.5	-0.4	0.6	-0.2
Smoking status: Previous	0.9	1.4	7.2	0.3	0.8	-0.6	1.0	0.1	-2.7	-1.1	0.4
Forced expiratory volume in 1-second (FEV1), predicted	0.6	1.2	2.3	0.1	-1.5	1.1	0.2	0.8	1.4	1.5	-1.0
Whole body fat-free mass	0.2	1.2	6.6	0.0	0.6	2.6	0.3	-1.1	0.4	-1.1	0.1
Leg fat-free mass (right)	0.3	1.3	4.5	0.1	1.1	2.1	0.6	-1.2	0.3	-1.7	0.5
Arm fat percentage (left)	1.7	6.6	19.2	1.5	4.2	-0.7	0.8	-2.5	-1.3	-4.4	2.3
Average weekly red wine intake	0.8	1.2	2.2	0.5	-1.4	-1.4	0.2	-0.5	1.5	1.4	-1.1
Handedness (chirality/laterality): Left-handed	1.3	1.5	4.2	1.4	0.9	0.4	2.0	-0.4	-1.2	-1.5	1.2
Mood swings	1.9	3.4	6.2	-1.9	-2.5	-1.5	-0.8	1.5	1.9	2.5	-1.6
Loneliness, isolation	0.6	0.9	2.9	-0.7	-1.1	-0.1	-0.5	-0.1	1.7	1.3	-0.6
Long-standing illness, disability or infirmity	0.9	1.4	3.0	-1.7	1.7	-1.6	-0.8	-0.5	-0.6	-0.4	1.3
Ever had bowel cancer screening	0.1	0.2	0.5	-0.2	0.4	0.5	0.7	-0.4	-0.2	-0.3	0.4
Diabetes diagnosed by doctor	1.1	1.8	3.5	1.4	1.9	-0.2	0.9	-1.4	-1.5	-1.6	1.3
Ever had stillbirth, spontaneous miscarriage or termination	0.5	0.5	2.0	-1.0	0.0	-0.3	-0.8	-0.4	1.4	0.1	-0.1
Friendships satisfaction	0.5	0.6	1.1	-0.5	-0.6	0.8	-0.8	0.7	0.7	1.1	-1.1
Qualifications: nursing, teaching	0.3	0.5	1.8	0.7	-0.1	-1.4	-0.5	-0.4	0.5	0.8	0.3
Commuting to job workplace: Walk	0.4	0.4	1.6	-0.6	0.2	-1.3	-0.4	-0.1	0.3	0.7	0.9
Eye problems/disorders: Cataract	0.7	0.8	3.9	0.0	-0.1	0.5	-2.0	0.3	0.7	0.7	-1.1
Mouth/teeth dental problems: Mouth ulcers	1.1	1.8	6.4	-2.5	-1.1	-0.7	-1.6	1.2	-0.6	1.2	-0.3
Medication for cholesterol	1.7	2.6	8.1	0.3	-2.8	1.0	0.4	1.0	-0.4	2.1	-2.3
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.3	0.3	1.3	0.8	-0.4	-0.2	1.1	0.4	-0.5	-0.4	0.3
Back pain experienced in last month	2.1	3.0	6.9	-2.1	-1.7	-1.0	-2.6	1.9	0.7	1.5	-1.6
Mineral and other dietary supplements	0.4	0.5	1.1	0.6	1.0	0.0	0.9	-0.6	-0.5	-1.0	0.7
Breast cancer (self-reported)	1.4	1.7	5.9	-0.2	-1.0	-0.3	-0.4	0.2	2.4	0.9	-2.3
Asthma (self-reported)	0.5	1.0	5.1	0.7	0.3	-2.3	0.3	-0.3	1.1	0.1	-0.8
Osteoporosis (self-reported)	0.9	1.1	4.3	-1.4	-0.4	0.4	-2.1	0.3	0.7	0.9	-0.9
Osteoarthritis (self-reported)	0.3	0.4	1.9	0.6	-0.8	1.4	0.1	0.4	0.0	0.1	-0.1
Medication: Aspirin	0.6	0.8	2.5	-1.1	-0.5	-1.6	-0.5	1.4	-0.0	0.5	0.2
Medication: Gliclazide	0.6	0.6	1.4	-0.8	0.7	-0.0	-1.1	0.4	-0.9	-0.5	1.2
Illnesses of father: None of the above (group 1)	0.1	0.1	0.5	0.7	-0.1	0.7	0.1	-0.1	0.1	-0.2	-0.4
Smoking status: Current	1.6	2.5	5.2	-1.6	-2.3	-0.2	-1.5	0.7	1.4	1.8	-2.0
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.8	1.7	3.9	-0.8	-0.1	-0.6	-2.0	-1.4	1.8	1.4	-1.1
Whole body water mass	0.2	1.2	6.3	-0.0	0.6	2.5	0.3	-1.1	0.4	-1.1	0.1
Leg predicted mass (right)	0.2	1.3	4.7	0.1	1.0	2.2	0.6	-1.1	0.4	-1.6	0.4
Arm fat mass (left)	1.2	4.7	14.6	1.3	3.3	0.3	0.9	-2.4	-0.9	-3.8	1.7
Number of self-reported non-cancer illnesses	0.3	0.5	1.3	-0.2	-0.1	-1.1	-0.8	1.2	0.6	0.2	-0.4
Average weekly champagne plus white wine intake	0.2	0.3	1.4	0.4	0.2	0.7	-0.2	0.4	1.2	-0.2	-0.3
Miserableness	3.4	5.9	13.3	-2.2	-3.6	-0.8	-1.1	2.0	2.4	3.7	-2.0
Guilty feelings	0.4	0.6	1.5	-0.5	0.1	-1.1	-0.2	1.2	1.1	0.6	0.5
Wears glasses or contact lenses	0.9	1.1	5.2	-1.1	-0.2	0.3	0.2	2.3	-0.8	-0.6	0.9
Ever taken oral contraceptive pill	0.4	0.4	1.7	-0.3	0.1	-1.3	-1.1	-0.4	0.1	-0.4	0.0
Hearing aid user	0.8	0.9	5.1	-0.5	1.2	-2.3	-0.5	0.0	-0.3	-0.4	0.4
Mother’s age at death	0.4	0.5	1.6	-0.4	-0.5	-0.1	-1.1	0.1	-0.4	1.3	-0.9
Financial situation satisfaction	0.2	0.3	0.9	-1.0	-0.5	-0.8	-0.4	0.1	0.2	0.5	-0.4
Tinnitus: Yes, now most or all of the time	0.6	0.7	1.9	-0.9	-0.1	-1.1	-0.6	0.1	1.4	0.6	-0.7
Commuting to job workplace: Public transport	1.3	1.5	3.7	-0.9	-1.0	-0.2	-1.2	1.2	1.9	1.1	-1.6
Eye problems/disorders: Glaucoma	1.0	1.2	3.7	-0.8	-0.8	-0.1	-1.0	0.2	1.9	1.0	-1.6
Medication: Blood pressure	0.9	1.7	6.2	-1.6	1.5	-2.5	-0.3	0.1	1.1	-0.8	1.0
Pain type(s) experienced in last month: Hip pain	1.2	1.5	2.6	-1.3	-1.2	-0.3	-1.6	0.6	1.3	1.4	-1.5
Supplements: Fish oil (including cod liver oil)	0.3	0.5	2.4	-0.1	-0.5	-0.8	0.0	1.5	-0.0	0.6	0.1
High cholesterol (Self-reported)	0.9	1.7	5.2	-0.2	2.3	0.7	-0.2	-0.6	0.1	-1.8	2.0
Medication: Bendroflumethiazide	0.8	1.2	8.7	0.1	-0.4	-2.9	-0.4	0.6	-0.0	-0.3	-0.2
Medication: Paracetamol	1.4	2.2	6.3	-2.4	-0.1	-2.5	-1.3	-0.1	1.6	0.9	-0.8
Medication: Lisinopril	0.8	1.1	4.9	0.9	1.2	-0.4	-0.2	-0.7	-0.3	-2.2	0.8
Medication: Atorvastatin	0.2	0.2	0.6	0.2	0.8	-0.5	-0.3	0.4	0.8	-0.3	-0.1
Illnesses of father: High blood pressure	1.1	1.4	4.5	-2.1	-0.5	-1.9	-0.1	-0.7	0.5	0.7	-1.2
Alcohol drinker status: Never	0.7	0.8	2.6	-1.4	0.1	-0.3	-0.4	1.0	1.6	0.8	0.2
Ever smoked	0.3	0.5	1.5	-0.6	-1.2	-0.1	0.6	0.6	-1.2	0.2	-0.7
Basal metabolic rate	0.3	1.5	5.7	0.3	1.1	2.4	0.5	-1.4	0.3	-1.6	0.3
Leg fat percentage (left)	1.7	6.0	16.6	1.7	3.6	0.0	0.8	-2.7	-1.8	-4.1	2.0
Arm fat-free mass (left)	0.3	1.7	7.2	0.6	0.8	2.7	0.5	-1.9	-0.3	-1.4	0.0
Number of operations (self-reported)	0.5	0.7	2.3	-0.4	0.7	0.7	-1.4	-0.4	1.5	0.2	-0.1
Average weekly beer plus cider intake	0.5	0.8	2.2	1.0	0.7	1.5	0.9	-0.4	-0.7	-0.8	0.5
Irritability	1.4	2.4	3.5	-1.4	-1.9	-1.0	-1.3	1.4	1.6	1.8	-1.7
Risk taking	0.8	1.1	5.7	0.8	-0.6	0.5	2.4	0.1	-0.6	-1.2	-0.1
Ever had prostate specific antigen (PSA) test	0.4	0.5	1.6	1.0	0.5	-1.3	0.2	0.0	-0.6	-0.2	0.7
Fractured/broken bones in last 5 years	0.6	0.8	3.1	-0.7	-0.3	1.0	-0.7	0.6	-1.8	-0.2	0.9
Age started oral contraceptive pill	0.9	1.1	2.7	0.4	-1.6	0.1	-0.6	0.9	0.9	1.3	-1.5
Diastolic blood pressure, automated reading	0.9	2.8	11.8	-2.4	-0.6	-1.1	-1.2	0.1	3.4	0.6	-1.4
Ever depressed for a whole week	0.6	0.7	1.4	-0.9	-0.3	-1.0	-0.9	0.3	1.2	1.1	-0.5
Unable to work because of sickness or disability	0.3	0.4	1.5	-1.0	0.6	-0.5	-1.2	0.0	0.1	-0.6	-0.1
Commuting to job workplace: Cycle	1.8	2.2	5.6	-0.4	-2.4	-0.3	-1.4	0.5	1.5	1.9	-1.9
Myopia	0.4	0.6	3.0	-0.3	-0.4	-0.7	1.7	0.2	0.9	-0.0	-0.7
Vascular/heart problems diagnosed by doctor	1.4	3.8	13.4	2.4	-1.9	3.7	1.8	1.1	-1.2	1.1	-0.9
Cholesterol lowering medication	0.4	0.6	1.7	-1.3	0.9	-0.3	-0.9	0.4	0.9	-0.1	0.5
Medication: Omeprazole (e.g. Zanprol)	0.3	0.3	0.9	-0.3	0.2	-0.2	0.4	-0.7	-1.0	-0.6	-0.6
Pain experienced in last month	3.0	5.0	11.4	3.4	1.8	1.8	3.1	-0.3	-1.5	-1.8	2.5
Supplements: Calcium	6.3	6.9	19.8	-0.8	-3.4	-0.2	-1.1	2.4	2.4	3.3	-4.5
Basal cell carcinoma (self-reported)	3.5	4.1	7.7	2.7	2.3	-0.9	1.1	-2.8	-1.7	-2.5	1.2
Heart attack/myocardial infarction (self-reported)	0.2	0.3	1.8	1.3	-0.2	0.0	0.3	-0.0	-0.3	-0.5	0.6
Deep venous thrombosis (DVT) (self-reported)	1.0	1.3	4.0	0.4	0.8	1.2	0.7	-0.2	-1.3	-1.4	2.0
Heart disease (siblings)	1.1	1.4	3.4	1.1	-1.8	-0.8	0.4	1.5	-0.9	0.7	-1.4
Alcohol drinker status: Previous	0.2	0.2	0.5	0.3	0.4	-0.7	0.6	-0.4	-0.3	-0.4	-0.7
Pack years of smoking	1.2	1.8	3.9	-0.7	-1.4	-0.0	-0.9	0.8	1.9	1.7	-2.0
Impedance of whole body	0.8	4.2	8.9	1.8	-2.9	-0.4	1.3	1.9	1.0	2.4	-3.0
Leg fat mass (left)	1.5	5.9	17.4	1.6	3.5	1.0	0.8	-2.7	-1.4	-4.2	2.0
Arm predicted mass (left)	0.3	1.5	6.2	0.4	0.8	2.5	0.2	-1.8	-0.2	-1.4	0.1