Hub : Genes

PPIL2

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Artery Aorta	0.1460	0.0620	4.5e-03	0.034	NA	0.016	NA	0.020	5.8e-03	NA	4.3e-02	NA	2.8e-02
2	GTEx	Artery Tibial	0.1206	0.0476	3.0e-03	0.067	NA	0.020	NA	0.056	5.5e-06	NA	1.0e-02	NA	3.1e-05
3	GTEx	Brain Caudate basal ganglia	0.4720	0.1020	1.4e-04	0.113	NA	0.118	NA	0.149	3.9e-04	NA	2.9e-04	NA	4.7e-05
4	GTEx	Brain Cortex	0.4130	0.0930	6.2e-05	0.214	NA	0.046	NA	0.042	1.5e-06	NA	2.1e-02	NA	2.6e-02
5	GTEx	Brain Frontal Cortex BA9	0.5817	0.1093	1.6e-04	0.101	NA	0.014	NA	0.100	1.3e-03	NA	1.4e-01	NA	1.3e-03
6	GTEx	Brain Hippocampus	0.3561	0.1257	9.3e-03	0.154	NA	0.179	NA	0.110	1.9e-04	NA	5.6e-05	NA	1.5e-03
7	GTEx	Esophagus Muscularis	0.1150	0.0400	2.8e-04	0.081	NA	0.076	NA	0.079	1.3e-05	NA	2.1e-05	NA	1.7e-05
8	GTEx	Nerve Tibial	0.1719	0.0505	1.8e-05	0.167	NA	0.143	NA	0.163	6.8e-12	NA	2.4e-10	NA	1.2e-11
9	GTEx	Pancreas	0.1440	0.0600	5.9e-03	0.079	NA	0.092	NA	0.092	3.2e-04	NA	1.1e-04	NA	1.0e-04
10	METSIM	Adipose	0.0462	0.0222	7.4e-03	0.002	0.012	0.000	0.012	0.003	1.3e-01	6.1e-03	2.8e-01	0.0061	9.1e-02
11	TCGA	Breast Invasive Carcinoma	0.0156	0.0091	8.1e-03	0.007	0.010	0.013	NA	0.013	1.0e-02	2.9e-03	7.2e-04	NA	9.8e-04
12	TCGA	Kidney Renal Clear Cell Carcinoma	0.0658	0.0263	8.1e-06	0.063	0.056	0.052	NA	0.044	1.3e-07	6.1e-07	1.6e-06	NA	1.1e-05
13	TCGA	Brain Lower Grade Glioma	0.0344	0.0186	4.8e-03	0.036	0.009	0.030	NA	0.020	5.6e-05	3.0e-02	2.2e-04	NA	2.2e-03
14	TCGA	Lung Squamous Cell Carcinoma	0.0316	0.0172	4.0e-03	0.002	0.017	0.000	NA	0.004	1.7e-01	4.4e-03	2.9e-01	NA	1.1e-01
15	TCGA	Prostate Adenocarcinoma	0.0435	0.0211	7.7e-04	0.046	0.024	0.028	NA	0.024	1.3e-05	1.4e-03	5.9e-04	NA	1.5e-03
16	TCGA	Thyroid Carcinoma	0.0470	0.0260	1.8e-03	0.036	0.030	0.034	NA	0.032	1.7e-04	5.8e-04	2.7e-04	NA	4.4e-04

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16
Bipolar Disorder (2018)	6.6	10.4	19.5	-2.7	-2.4	-3.9	-3.7	-3.6	-3.0	-3.6	-3.1	-3.6	1.1	3.4	4.4	3.4	2.0	3.1	3.3
Bipolar Disorder or Schizophrenia	3.7	9.0	18.7	-0.9	-2.4	-3.0	-3.1	-3.8	-2.0	-2.2	-1.5	-2.7	2.4	3.7	4.3	4.2	-0.0	4.1	3.5
Depressed Affect (Nagel 2018)	0.4	0.8	4.7	-1.0	-1.5	-1.0	-0.3	-0.8	-0.1	-0.8	-0.9	-0.7	-2.2	1.1	-0.3	0.1	-0.1	-0.7	0.3
Depression (Nagel 2018)	0.2	0.4	3.6	-0.6	-0.4	0.6	0.3	0.2	-0.7	0.2	-0.0	0.0	-1.9	0.1	-0.4	-0.2	-0.2	-0.4	-0.3
Intelligence (Savage-Jansen 2018)	0.1	0.3	3.3	0.6	-0.4	-0.1	0.2	0.2	0.1	0.7	0.2	0.2	1.8	0.1	0.0	-0.0	-0.6	0.4	0.1
Neuroticism (Nagel 2018)	0.4	1.0	1.9	-1.4	-1.4	-1.0	-1.0	-1.2	-0.7	-1.4	-1.2	-0.9	-1.3	0.9	0.5	0.3	0.8	-0.1	0.4
Schizophrenia (2018)	1.3	2.7	7.6	1.1	-1.2	-0.9	-1.1	-2.0	-0.1	0.1	0.6	-0.5	2.3	2.0	1.9	2.8	-1.7	2.7	1.9
Schizophrenia vs Biploar Disorder	1.6	2.1	5.9	0.0	-0.1	2.2	1.4	0.9	1.6	1.4	0.7	1.4	-0.8	-1.3	-2.4	-2.1	-0.7	-1.8	-1.8
Worry (Nagel 2018)	0.1	0.2	1.1	-0.3	0.6	-0.0	-0.5	0.1	-0.4	-0.7	-0.1	-0.2	0.2	-0.1	1.0	0.4	0.8	0.4	0.2
Alzheimer’s Disease (in mother)	0.5	0.6	2.4	1.5	1.3	0.1	-0.1	0.6	-1.4	0.4	0.5	0.1	-0.1	0.1	-0.1	0.7	-1.6	-0.0	0.4
Alzheimer’s Disease (in father)	0.2	0.3	0.7	-0.8	-0.8	0.3	-0.2	-0.6	-0.1	-0.5	-0.3	-0.4	-0.6	0.6	0.7	0.4	0.5	0.2	0.3
Alzheimer’s Disease (including proxy)	0.5	0.7	3.5	1.2	0.7	0.7	0.8	0.5	-0.1	0.6	0.5	0.6	-0.3	-0.3	-1.0	-0.1	-1.9	-1.4	-0.7
Crohns Disease (2017)	3.9	8.5	31.9	-1.7	-1.4	-1.9	-3.2	-2.6	-1.4	-2.3	-2.4	-2.2	1.9	1.8	4.7	1.9	5.6	4.7	2.2
Irritable Bowel Disease (IBD)	2.5	5.9	22.2	-1.3	-0.7	-1.1	-2.5	-2.0	-0.7	-1.3	-1.7	-1.7	1.7	1.3	4.3	1.7	4.7	4.5	2.0
Ulcerative Colitis (UC)	0.5	0.9	4.1	0.2	0.4	0.3	-0.5	-0.6	0.7	0.4	0.1	0.1	1.6	0.1	1.8	0.5	1.6	2.0	0.6
Major Depression (MDD)	0.2	0.3	1.8	-0.1	0.6	-0.6	0.2	0.4	0.1	-0.2	-0.6	-0.3	-1.3	-0.3	-0.4	-0.1	-0.3	-1.0	-0.3
Reaction Time	1.2	2.4	5.8	1.6	-0.5	0.7	1.8	1.2	1.2	1.6	1.0	1.7	-1.7	-0.9	-2.4	-2.4	0.1	-1.8	-1.9
Verbal and Numeric Reasoning (VNR)	0.2	0.5	6.0	-0.3	-0.6	-0.5	-0.3	-0.0	-0.6	-0.1	-0.6	-0.3	2.5	0.1	-0.2	-0.3	0.2	0.3	0.1
Breast Cancer	0.2	0.4	2.7	-0.0	0.3	0.4	0.1	0.0	0.1	0.8	0.3	-0.1	1.0	0.3	-0.5	0.9	-1.6	0.2	0.7
Ovarian Cancer	0.6	0.8	2.8	0.2	1.6	0.8	0.1	0.3	0.2	0.3	1.5	0.7	1.0	-0.6	0.6	1.1	-1.7	0.5	-0.0
Prostate Cancer	1.8	2.5	4.3	-1.2	-1.6	-1.7	-2.0	-1.5	-1.3	-1.8	-1.9	-1.9	0.7	2.1	1.0	1.5	0.9	1.5	1.9
Age at First Birth	0.1	0.2	0.6	0.1	-0.4	-0.0	-0.3	-0.6	-0.5	-0.5	-0.6	-0.5	0.2	0.8	0.3	0.4	0.4	0.3	0.3
Bipolar Disorder (2011)	1.7	1.6	7.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	2.0	2.7	2.2	0.6	2.3	1.9
Body Mass Index (BMI) (2010)	0.6	0.8	5.2	-1.0	-0.2	-0.2	0.4	0.9	0.2	-0.1	-0.8	0.1	-0.4	-0.9	0.1	-1.4	2.3	-0.5	-1.2
Coronary Artery Disease (CAD)	4.1	4.9	11.4	-2.3	-3.4	-2.4	-2.2	-2.2	-1.5	-2.7	-2.6	-2.7	-1.3	2.7	1.7	1.5	1.8	1.5	1.9
Crohns Disease (2012)	1.3	2.1	11.9	-0.5	0.7	0.4	-1.0	-0.2	-0.2	-0.2	-0.1	-0.1	2.2	-0.5	2.8	0.5	3.4	2.5	0.3
Mean Putamen Volume	0.1	0.2	1.1	0.1	-0.0	0.4	-0.3	-0.2	0.0	0.3	0.3	-0.1	1.0	0.1	-0.6	0.2	0.1	0.5	0.4
Fasting Glucose	0.1	0.2	0.9	0.3	-0.6	0.0	0.1	-0.0	-0.1	0.4	0.2	0.5	0.9	-0.1	-0.1	-0.5	0.5	0.6	-0.5
HbA1C	0.5	0.6	1.8	-0.6	-0.5	-0.6	-0.5	-1.2	-1.2	-0.3	-0.4	-0.5	-0.4	1.3	0.7	0.7	0.3	0.9	0.9
HDL Cholesterol	5.7	9.5	24.9	3.2	3.3	2.7	3.7	3.0	2.0	3.3	3.9	3.2	1.1	-2.8	-3.0	-1.3	-5.0	-3.3	-2.4
LDL Cholesterol	0.7	1.1	3.6	-0.9	-1.0	-0.7	-1.0	-1.6	-1.7	-1.9	-1.3	-1.2	0.5	1.1	0.2	0.7	0.0	-0.1	0.5
Lupus	1.9	2.9	11.2	-1.0	0.2	-0.3	-2.1	-1.7	0.9	-0.5	-0.4	-0.6	2.1	0.3	2.8	0.7	3.3	3.3	1.1
Neuroticism (2016)	1.5	2.2	6.7	-2.6	-2.3	-1.6	-0.3	-0.6	-0.2	-1.5	-2.0	-1.0	-2.2	0.8	-0.3	-1.2	1.9	-1.4	-0.2
Primary Biliary Cirrhosis	1.3	1.8	4.0	-1.4	-0.7	-0.8	-1.8	-0.8	-1.4	-1.7	-2.0	-1.8	-0.4	0.9	1.2	1.0	1.8	1.4	1.3
Rheumatoid Arthritis	0.5	0.7	4.9	-1.5	-0.5	0.6	0.1	0.1	0.1	0.1	-0.1	-0.1	0.4	-0.2	1.2	-0.2	2.2	1.1	-0.0
Schizophrenia (2014)	1.8	4.0	9.0	0.3	-1.8	-1.5	-1.8	-2.7	-0.7	-0.6	-0.4	-1.5	2.5	2.6	2.5	3.0	-0.7	3.0	2.4
Triglycerides	0.3	0.5	3.1	0.5	-1.1	-0.0	0.2	0.1	0.2	-0.0	0.1	0.2	-0.3	0.3	-1.4	-0.2	-1.8	-1.3	-0.2
Type 2 Diabetes (T2D) (2012)	0.5	0.6	3.2	-1.8	-0.4	-0.9	-0.3	-0.1	0.5	-0.9	-1.3	-0.1	-0.5	0.1	-0.6	-0.4	1.3	-0.4	0.2
Ulcerative Colitis	0.7	1.0	4.6	-0.2	0.0	0.4	-0.3	-0.2	0.8	0.3	0.2	-0.2	1.2	0.3	2.1	0.9	1.6	2.1	0.8
Blood Eosinophil Count	0.3	2.6	10.8	-1.0	-0.1	0.0	-1.6	-1.7	-0.6	-0.7	-0.7	-1.1	0.4	0.9	3.0	1.3	2.8	3.3	1.4
Blood Platelet Count	0.1	1.5	2.7	1.4	1.3	1.6	1.3	1.5	0.7	1.2	1.1	1.3	0.9	-1.4	1.5	-0.4	1.2	0.9	-1.0
Blood Red Count	0.6	5.9	20.5	-1.3	-1.7	-1.6	-2.3	-3.2	-2.1	-1.9	-1.0	-2.0	1.5	2.4	4.5	3.0	1.3	3.8	2.2
Blood White Count	0.2	1.9	8.2	-0.1	-1.1	-0.3	1.0	-0.2	-0.2	-0.6	-0.2	0.2	-2.5	0.2	-1.8	-0.6	-2.8	-2.9	-1.1
Heel T-Score	0.2	1.6	9.4	0.6	-1.3	-1.0	0.4	0.3	-1.2	-0.8	-0.2	-0.1	-0.5	0.2	-1.9	-0.1	-3.1	-2.5	-0.9
BMI	1.1	6.2	20.8	-2.9	-2.5	-2.3	-2.2	-1.7	-1.9	-3.3	-3.7	-2.9	-2.7	1.9	1.5	0.0	4.6	0.6	1.3
Height	1.6	30.0	56.1	4.2	4.8	6.3	6.1	6.0	4.6	6.8	5.4	5.3	-1.4	-5.0	-7.5	-4.4	-6.6	-6.1	-4.3
Waist Hip Ratio (WHR)	0.4	2.0	7.0	-0.7	-0.3	-0.5	-1.4	-1.2	-1.1	-0.5	-0.5	-1.3	1.2	1.6	2.0	2.3	0.2	2.6	2.1
Systolic Blood Pressure	0.6	3.2	11.7	0.9	0.5	1.3	2.0	1.7	0.7	1.6	0.7	1.1	-1.5	-1.2	-3.4	-1.7	-2.9	-3.0	-1.3
Smoking Status	0.1	0.2	1.7	0.0	-0.4	-0.1	0.5	0.4	1.3	0.1	0.4	0.3	-0.5	-0.3	0.4	-0.2	-0.4	-0.4	-0.5
Allergy or Eczema	1.6	4.1	14.6	-1.5	-0.4	-0.8	-1.9	-2.1	-1.4	-1.3	-1.3	-1.5	1.8	1.3	3.4	1.4	3.8	3.3	1.7
Cardiovascular Disease	0.5	1.7	6.5	-1.0	-2.5	-1.8	-0.4	-1.7	-0.5	-1.6	-1.7	-0.6	-0.7	0.9	-0.8	-1.3	1.3	-1.5	-0.6
Hypothyroidism (self reported)	0.8	1.8	5.9	-0.5	-0.6	-0.3	-1.6	-1.8	-1.5	-1.2	-0.4	-0.8	0.0	1.0	2.1	1.2	1.8	2.4	1.1
Respiratory disease	0.8	1.8	5.1	-1.2	-1.2	-1.1	-1.4	-1.0	-0.6	-1.7	-1.6	-1.5	-0.6	1.1	2.0	0.9	2.3	1.3	1.1
Type 2 Diabetes (T2D) (2018)	1.8	3.3	13.3	-1.8	-1.0	-1.8	-1.7	-1.7	-1.7	-2.4	-2.3	-2.1	-0.9	1.2	1.8	0.5	3.6	1.4	0.9
Lung FEV1/FVC ratio	0.1	0.6	3.1	0.9	0.3	0.7	0.7	0.8	0.5	0.5	0.3	0.4	-0.6	-0.3	-1.8	-0.6	-1.2	-1.2	-0.5
Lung FVC	1.5	7.5	15.5	3.9	2.1	2.2	3.3	2.9	2.6	3.8	3.9	3.7	1.8	-2.4	-1.1	-1.8	-2.2	-1.1	-2.5
Neuroticism	0.5	1.2	2.4	-1.1	-1.3	-1.5	-1.4	-1.5	-1.1	-1.5	-1.2	-1.1	-0.7	1.3	0.0	0.6	0.2	-0.2	0.8
Chronotype (morning person)	3.0	6.9	12.8	-1.9	-1.3	-2.8	-3.2	-2.7	-3.2	-2.8	-2.3	-3.0	0.3	3.1	2.2	3.6	0.4	2.9	3.5
Hair Pigment	0.1	3.3	9.4	-0.5	-0.8	-1.8	-1.9	-2.4	-1.6	-1.2	-0.8	-1.4	3.1	2.3	1.7	2.3	-0.1	2.0	2.1
Tanning	0.1	1.4	8.9	1.1	1.2	0.3	0.9	0.1	1.6	1.1	1.7	1.2	-0.2	-0.5	-0.5	0.7	-3.0	-0.9	-0.2
Hand grip strength (left)	1.6	4.2	12.6	1.7	1.8	1.3	2.0	1.6	1.6	2.1	2.0	2.0	-1.7	-1.5	-3.5	-1.6	-2.7	-2.6	-1.5
Number of treatments/medications taken	0.4	0.8	2.5	-0.9	-0.9	-0.5	-0.6	-0.3	-0.7	-1.1	-1.2	-0.7	1.6	0.7	1.1	0.2	1.4	0.6	0.2
Average weekly spirits intake	0.2	0.2	0.9	-0.7	-0.3	-0.4	-0.1	-0.0	-0.7	-0.2	-0.9	-0.4	0.5	0.4	-0.3	-0.5	0.5	-0.5	0.1
Sensitivity / hurt feelings	0.4	0.6	1.8	-1.3	-0.9	0.3	-0.5	-0.5	0.4	-0.9	-1.3	-0.8	-1.2	-0.2	0.6	-0.5	1.3	-0.4	-0.3
Frequency of depressed mood in last 2 weeks	0.4	0.5	3.9	-1.5	-0.4	0.3	0.2	-0.2	-0.8	0.2	-0.2	-0.2	-2.0	0.4	-0.5	-0.3	-0.5	-0.6	-0.1
Hearing difficulty/problems: Yes	0.4	0.5	2.2	0.3	0.7	1.1	-0.3	-0.2	-0.3	0.3	0.2	-0.2	1.4	0.1	0.9	0.9	-0.1	1.5	0.5
Relative age of first facial hair	0.5	1.0	2.4	-0.0	1.2	0.8	1.2	1.4	0.6	0.5	0.6	0.8	-1.2	-1.6	-0.1	-1.2	0.5	-0.8	-1.4
Other serious medical condition/disability diagnosed by doctor	4.7	6.2	12.2	-2.3	-1.7	-1.6	-2.9	-2.1	-2.1	-2.1	-3.2	-3.1	0.4	2.5	2.9	1.8	3.5	2.9	2.9
Ever used hormone-replacement therapy (HRT)	0.4	0.6	1.7	0.1	0.2	-0.3	-0.7	-0.8	-0.6	-0.1	-0.8	-1.0	0.1	1.3	0.1	1.1	-0.9	0.7	1.3
Ever had hysterectomy (womb removed)	0.1	0.1	1.0	-0.6	0.5	0.0	-0.1	-0.3	0.4	0.0	-0.3	0.0	1.0	0.0	-0.4	0.0	-0.3	-0.4	0.0
Systolic blood pressure, automated reading	0.6	1.9	5.6	1.1	1.0	1.4	1.6	1.5	0.4	1.3	0.5	0.7	-0.6	-1.0	-2.1	-1.1	-2.4	-2.3	-1.0
Eye problems/disorders: Diabetes related eye disease	0.1	0.2	0.7	0.1	-0.2	-0.4	0.4	-0.1	0.1	-0.1	0.4	0.5	0.8	-0.1	-0.4	-0.5	0.3	-0.5	-0.6
Angina	0.7	1.0	2.1	-1.0	-1.1	-1.5	-1.3	-1.1	-0.8	-1.3	-1.5	-1.1	0.5	1.0	-0.0	0.2	0.7	0.2	0.8
Medication for hormone replacement therapy	1.0	1.1	3.2	-0.4	-1.7	-1.8	-0.8	-0.8	-0.6	-1.1	-1.5	-1.2	-0.9	1.8	-0.3	0.5	-0.0	-0.0	1.0
Vitamin and mineral supplements	0.9	1.2	4.0	1.1	-0.3	0.2	1.4	1.0	0.5	0.7	0.7	1.1	0.6	-0.6	-1.6	-1.5	-0.7	-2.0	-1.3
Supplements: Zinc	3.9	4.2	8.8	-1.9	-1.8	-2.6	-2.6	-3.0	-1.4	-2.0	-2.1	-2.1	-1.5	2.5	1.5	1.8	1.1	1.9	2.3
Medication: Co-codamol	0.4	0.5	2.3	0.6	-1.5	-0.5	0.5	0.0	0.6	0.2	0.6	0.7	-0.8	0.3	-0.9	-0.2	-1.1	-0.8	-0.5
Medication: Metformin	1.2	1.6	3.3	-1.1	-1.0	-1.2	-1.4	-1.6	-1.8	-1.8	-1.5	-1.4	-0.9	1.3	0.7	0.4	1.8	0.6	0.7
Diabetes (father)	1.9	2.4	6.6	1.1	2.3	2.6	1.4	1.7	1.7	1.1	1.8	1.7	0.2	-2.5	-0.1	-0.8	-0.2	-0.4	-1.6
Diabetes (mother)	0.7	0.8	2.2	0.1	0.0	0.7	0.7	1.0	1.3	-0.3	-0.1	0.3	-1.3	-1.5	-0.0	-1.2	0.5	-1.3	-1.4
Severe depression (siblings)	1.5	1.6	3.4	-1.8	-1.3	-0.7	-1.2	-0.9	-1.4	-1.4	-1.3	-1.6	-1.0	1.3	1.4	1.3	1.2	1.2	1.2
Pack years adult smoking proportion	1.2	1.8	3.8	1.1	0.1	1.3	1.6	1.1	0.5	1.0	1.1	1.5	1.1	-1.2	-1.9	-1.9	-1.1	-1.9	-1.7
Impedance of leg (right)	1.5	7.3	40.3	3.8	1.4	1.8	2.5	1.7	1.8	3.1	3.5	2.7	0.9	-1.3	-3.0	0.1	-6.3	-1.6	-1.1
Leg fat-free mass (left)	0.2	1.2	6.5	-1.3	-0.3	0.9	0.2	0.4	0.3	-0.4	-0.8	-0.2	-2.6	-0.5	-1.0	-1.5	1.8	-1.4	-0.6
Trunk fat percentage	0.1	0.2	0.8	0.2	-0.4	0.6	-0.1	0.2	-0.1	-0.5	-0.6	-0.5	-0.9	0.2	-0.7	0.1	-0.2	-0.8	0.0
Hand grip strength (right)	2.1	5.7	9.2	2.1	2.1	2.4	2.6	2.3	2.3	2.7	2.9	2.7	-0.9	-2.2	-3.0	-1.7	-3.0	-2.3	-2.0
Townsend deprivation index at recruitment	0.4	0.5	2.1	-1.4	-0.1	-0.7	-1.0	-0.5	-0.7	-0.9	-0.5	-0.7	-0.5	0.2	1.0	0.4	0.8	0.4	0.5
Current tobacco smoking	0.3	0.4	1.3	0.5	-0.4	0.0	1.0	0.3	0.4	0.6	0.9	1.0	-0.0	-0.6	0.0	-0.6	-0.5	-0.7	-1.2
Average weekly fortified wine intake	0.3	0.3	0.8	-0.1	-0.8	-0.6	-0.7	-0.9	-0.5	-0.8	-0.8	-0.6	-0.1	0.5	-0.5	-0.2	-0.3	-0.7	0.3
Maternal smoking around birth	0.1	0.1	0.7	0.1	-0.6	0.1	-0.3	-0.6	-0.0	-0.5	-0.0	-0.0	-0.0	0.2	-0.4	0.0	-0.8	-0.3	-0.2
Fed-up feelings	0.4	0.8	5.5	-1.6	-1.2	-0.5	-0.2	-0.4	0.5	-0.3	-0.6	-0.4	-2.3	0.4	-0.4	-0.4	0.3	-0.8	0.1
Frequency of unenthusiasm / disinterest in last 2 weeks	0.6	0.8	2.9	-1.2	-1.7	-0.6	-0.5	-0.5	-1.0	-0.4	-1.0	-0.9	-1.7	1.4	-0.0	0.1	0.6	0.2	0.7
Relative age voice broke	0.5	0.8	3.6	-1.6	-0.7	-0.6	-0.1	-0.5	-1.4	-1.0	-1.1	-0.7	-0.8	0.2	0.4	-0.7	1.9	-0.1	-0.3
Taking other prescription medications	1.0	1.6	5.5	-0.8	-0.6	-0.7	-1.2	-0.5	-0.8	-2.2	-1.6	-1.6	0.3	0.7	2.3	1.0	1.9	1.2	0.5
Age when periods started (menarche)	1.2	3.0	10.4	2.8	0.7	0.8	0.9	-0.4	-1.0	1.7	2.5	1.2	3.2	0.7	0.5	1.8	-3.2	1.1	0.5
Bilateral oophorectomy (both ovaries removed)	0.6	0.7	1.8	-0.6	-0.0	-0.6	-0.5	-1.0	-1.1	-0.3	-0.5	-0.7	0.6	1.0	1.4	1.2	0.2	1.1	1.1
Heel bone mineral density (BMD) T-score, automated (left)	1.0	2.4	11.6	0.5	-1.6	-0.6	1.4	0.9	0.6	-0.0	0.1	1.1	-0.1	-1.0	-2.4	-2.5	-0.5	-3.4	-2.4
Tinnitus: Yes, but not now, but have in the past	0.7	0.7	5.1	-0.3	1.3	0.0	-0.1	0.3	0.4	-0.2	-0.5	-0.4	-2.3	-1.0	-1.1	-0.5	-0.7	-1.2	0.0
Qualifications: CSEs or equivalent	0.2	0.3	1.4	0.0	0.0	-0.3	-0.0	0.2	-0.6	-0.7	-0.3	0.0	-1.0	-0.5	0.8	-0.5	1.2	-0.4	-0.6
Serious illness, injury or assault to yourself	0.2	0.3	1.0	-0.3	-0.2	-0.7	-0.6	-0.4	-0.8	-0.2	-0.5	-0.5	1.0	0.3	0.0	-0.0	0.6	0.5	0.3
High blood pressure	0.3	0.8	3.1	0.9	-1.3	-0.6	0.8	-0.1	0.3	-0.0	-0.2	0.6	0.5	-0.0	-1.2	-1.6	0.3	-1.8	-1.4
Hayfever, allergic rhinitis or eczema	1.3	2.9	12.5	-1.5	-0.7	-0.3	-1.7	-1.8	-0.6	-1.1	-0.9	-0.9	1.1	0.8	2.9	1.0	3.5	3.1	1.2
Multivitamins +/- minerals	0.3	0.3	1.2	-1.1	0.7	-0.4	-0.4	-0.0	0.0	-0.2	-0.4	-0.7	-0.7	0.1	0.8	0.7	0.3	0.7	0.6
Stomach or abdominal pain in last month	1.9	2.4	5.1	-2.2	-1.4	-1.6	-1.9	-1.7	-0.4	-1.9	-2.3	-1.9	-1.8	1.8	0.3	0.6	0.9	0.0	1.6
Supplements: Glucosamine	0.5	0.6	1.7	-0.9	-0.6	-0.7	-0.5	-0.9	-1.1	-0.0	-1.1	-1.1	-0.6	1.3	-0.0	0.6	-0.4	0.4	1.1
Diverticular disease/diverticulitis (self-reported)	0.8	0.9	8.4	-0.2	-2.9	-1.1	-0.6	-0.4	0.4	-1.1	-0.7	-0.5	0.5	1.2	0.4	0.2	0.3	-0.1	0.3
Medication: Atenolol	0.4	0.5	4.8	0.1	-0.8	-0.8	-0.2	-0.2	-0.0	-0.7	-0.2	-0.2	2.2	0.6	0.8	0.4	0.6	0.7	0.1
Medication: Levothyroxine sodium	0.8	1.4	4.2	-0.8	-0.5	-0.3	-1.6	-1.8	-1.5	-1.5	-1.1	-0.9	-0.5	0.7	1.4	0.4	2.0	1.4	0.7
Sitting height	2.5	17.4	40.4	2.9	2.8	4.0	4.5	4.5	3.7	4.3	3.5	3.7	-2.5	-3.3	-6.4	-3.3	-5.9	-5.9	-3.3
Chronic bronchitis/emphysema (father)	1.1	1.3	3.3	-0.8	-0.2	-0.8	-1.4	-1.1	-0.3	-1.2	-0.9	-1.5	0.7	1.2	1.6	1.8	-0.2	1.4	1.5
High blood pressure (mother)	0.4	0.5	1.0	1.0	0.3	0.8	0.7	0.6	0.5	0.4	0.8	0.8	1.0	-0.9	-0.7	-0.6	-0.5	-0.7	-0.9
Body mass index (BMI)	0.5	2.0	5.4	-1.3	-1.5	-1.0	-1.5	-1.2	-1.1	-2.2	-2.1	-1.7	-1.1	1.3	1.1	0.5	2.3	0.5	0.9
Impedance of leg (left)	1.3	6.2	39.5	3.3	1.2	1.6	2.3	1.5	1.5	2.8	3.2	2.3	1.1	-0.9	-2.6	0.4	-6.3	-1.5	-0.9
Leg predicted mass (left)	0.2	1.2	7.0	-1.4	-0.4	0.7	0.1	0.4	0.2	-0.5	-0.9	-0.3	-2.6	-0.4	-0.9	-1.4	1.9	-1.4	-0.6
Trunk fat mass	0.1	0.4	2.3	0.1	-0.3	0.9	0.1	0.3	0.0	-0.3	-0.5	-0.3	-1.5	0.1	-1.2	-0.3	-0.2	-1.2	-0.1
Waist circumference	0.2	0.7	2.4	-0.5	-0.6	0.1	-0.8	-0.3	-0.4	-1.2	-1.3	-1.2	-1.5	0.8	0.4	0.5	0.9	0.1	0.7
Number of incorrect matches in round	0.3	0.5	1.5	-0.1	0.5	0.1	-1.0	-0.8	-1.0	-0.3	-0.6	-0.8	0.4	0.9	0.3	1.1	-0.1	0.8	1.2
Past tobacco smoking	0.2	0.4	1.0	0.2	1.0	0.6	0.5	0.2	-0.7	0.6	0.5	0.7	-0.5	-0.7	-0.8	-0.6	-0.1	-0.6	-0.6
Alcohol usually taken with meals	0.8	1.3	3.4	-0.9	-1.3	-0.8	-0.9	-1.2	-1.9	-0.6	-1.0	-1.4	-1.6	1.6	0.6	1.3	-0.2	0.5	1.5
Nervous feelings	0.3	0.5	2.7	-0.3	-0.1	-0.2	0.4	0.8	0.3	-0.5	-0.0	0.3	-0.3	-0.7	0.7	-1.0	1.7	-0.5	-1.1
Frequency of tenseness / restlessness in last 2 weeks	0.6	1.0	3.1	-0.6	-1.5	-0.6	-0.6	-1.2	-0.5	-0.2	-0.3	-0.7	-0.7	1.8	0.7	1.5	-0.7	1.3	1.4
Hearing difficulty/problems with background noise	0.8	1.3	3.3	-0.5	-0.8	0.2	-1.5	-1.5	-0.7	-0.9	-1.3	-1.2	1.0	0.7	1.6	1.0	1.2	1.8	1.0
Hair/balding pattern: Pattern 2	0.5	0.6	4.2	-0.8	-0.8	-0.5	-0.1	-0.5	-0.1	-0.8	-0.5	-0.2	0.6	-0.2	1.5	-0.5	2.1	0.1	-0.5
Had menopause	3.5	4.4	7.7	2.4	2.7	2.6	1.8	2.5	1.8	2.8	2.1	1.9	1.8	-1.9	-2.1	-0.9	-2.5	-1.1	-1.2
Had other major operations	2.1	2.6	7.5	2.2	1.0	2.2	1.4	1.1	2.7	1.9	2.5	1.7	1.1	-1.2	-0.4	0.1	-2.1	0.1	-0.8
Forced vital capacity (FVC)	1.9	7.3	12.6	2.2	2.3	2.6	3.5	3.2	1.6	3.3	3.4	3.5	0.7	-2.6	-2.6	-2.4	-2.3	-2.6	-2.7
Heel bone mineral density (BMD) T-score, automated (right)	0.5	1.2	6.1	0.1	-2.2	-1.5	0.4	-0.3	-0.3	-0.6	-0.6	0.0	0.3	0.2	-1.4	-1.3	-0.6	-2.5	-1.1
Ever unenthusiastic/disinterested for a whole week	2.7	3.3	5.1	-1.8	-1.4	-2.0	-2.2	-1.8	-1.7	-2.2	-2.1	-2.3	-0.4	2.0	1.9	1.9	1.0	1.4	1.9
Qualifications: None of the above	0.6	1.3	4.5	-0.3	-1.0	-1.3	-1.0	-0.7	-2.1	-1.5	-0.8	-0.9	-1.8	1.3	1.1	1.2	0.7	0.6	0.8
Financial difficulties in last 2 years	0.3	0.4	0.8	0.6	0.8	0.8	0.2	0.9	0.7	0.8	0.7	0.3	-0.6	-0.2	0.6	0.5	-0.6	0.7	0.3
Mouth/teeth dental problems	0.4	0.7	5.0	0.2	0.5	-0.1	-0.3	-0.3	0.3	0.8	0.1	-0.1	0.2	0.7	-1.5	0.7	-2.2	-0.4	1.0
Heart attack	0.4	0.5	2.6	0.1	-1.1	-1.6	-0.1	-0.1	-0.1	-1.1	-0.2	-0.1	1.3	0.4	-0.0	-0.1	0.9	-0.0	-0.2
Allergy	0.6	1.5	10.0	0.9	1.1	0.1	1.1	1.1	0.1	1.1	0.9	0.5	-0.6	-0.4	-1.8	-0.0	-3.2	-1.7	-0.5
Pain all over the body in last month	2.1	2.2	8.5	-2.3	-1.1	-1.0	-1.5	-0.8	-1.6	-1.8	-2.5	-1.6	0.6	0.6	1.1	-0.1	2.9	0.3	0.6
Diabetes (self-reported)	2.1	3.2	11.6	-2.3	-0.7	-1.5	-1.9	-1.5	-1.9	-2.1	-2.3	-2.1	-0.4	1.0	1.9	0.5	3.4	1.4	1.0
Hayfever/allergic rhinitis (self-reported)	0.7	0.9	4.0	-0.5	-1.7	-0.8	-0.5	-1.2	-0.0	-0.6	-0.5	-0.3	0.1	1.0	1.4	0.1	2.0	1.1	0.3
Medication: Ramipril	1.5	1.9	5.5	-0.7	-1.9	-1.4	-1.2	-2.3	-1.5	-1.4	-1.1	-1.3	0.5	2.3	1.0	1.1	0.5	0.8	1.2
Medication: Simvastatin	1.0	1.5	5.5	-1.1	-2.4	-1.3	-0.9	-1.7	-1.4	-1.2	-1.8	-1.2	0.7	1.8	0.1	-0.2	0.3	-0.3	0.5
Fluid intelligence score	0.2	0.4	3.4	-0.0	-0.6	-0.2	0.2	0.8	0.2	0.0	-0.3	0.0	1.8	-0.5	-0.1	-0.9	1.0	-0.1	-0.5
Illnesses of siblings	0.1	0.2	0.5	0.1	0.3	-0.5	-0.7	-0.6	-0.3	-0.6	0.0	-0.2	0.4	0.2	0.2	0.5	-0.3	0.7	0.4
Neuroticism score	0.4	0.8	1.9	-1.4	-1.1	-1.1	-0.9	-0.6	-0.2	-1.0	-1.3	-1.0	-1.1	0.8	0.3	0.2	0.3	-0.2	0.6
Weight	0.1	0.6	3.9	-0.3	-0.3	0.9	0.2	0.4	0.3	-0.1	-0.5	-0.2	-2.0	-0.0	-1.3	-0.7	0.3	-1.4	-0.3
Impedance of arm (right)	0.4	1.8	4.9	2.0	0.8	0.5	1.1	1.2	1.4	1.6	1.6	1.4	1.0	-1.0	-1.8	-0.6	-2.2	-0.7	-0.8
Arm fat percentage (right)	0.4	1.7	4.4	-1.1	-1.6	-1.0	-1.4	-1.1	-0.9	-1.9	-2.1	-1.7	-0.6	1.4	0.7	0.4	1.9	0.4	1.0
Trunk fat-free mass	0.3	1.6	5.6	-0.2	0.4	1.6	1.1	0.9	0.6	0.9	0.3	0.7	-2.4	-0.6	-2.2	-1.6	-0.4	-2.1	-0.9
Hip circumference	0.2	1.0	3.2	0.5	0.7	1.5	0.7	1.2	0.6	0.4	0.1	0.4	-1.8	-0.8	-1.4	-1.0	-0.3	-1.6	-0.7
Time employed in main current job	0.9	1.0	7.1	1.9	0.5	0.5	0.4	-0.2	1.2	1.0	1.2	0.7	-0.4	-0.2	-0.3	0.5	-2.7	-0.2	-0.2
Alcohol intake versus 10 years previously	0.3	0.5	1.6	-0.2	-1.3	-0.1	-0.6	-0.6	0.4	-1.1	-0.3	-0.5	-0.1	0.5	1.2	1.0	0.0	0.7	0.4
Father’s age at death	0.3	0.4	2.1	0.5	0.7	0.5	0.1	-0.3	0.2	0.9	0.4	0.3	-0.7	0.1	-1.3	0.1	-1.4	-0.5	0.3
Worrier / anxious feelings	1.4	2.7	4.7	1.3	2.0	2.2	1.7	2.0	0.8	2.1	1.7	1.9	0.3	-1.8	-1.8	-1.5	-1.5	-1.4	-1.4
Frequency of tiredness / lethargy in last 2 weeks	0.5	0.8	2.1	-1.4	-0.6	-0.6	-0.8	-0.7	-1.0	-1.0	-1.4	-1.2	-0.1	1.2	0.2	0.8	0.4	0.5	1.0
Falls in the last year	0.1	0.2	0.8	-0.0	0.3	-0.2	-0.2	-0.3	-0.8	-0.2	-0.3	0.1	-0.9	0.1	-0.6	-0.3	-0.2	-0.5	-0.3
Hair/balding pattern: Pattern 3	0.5	0.7	4.2	0.2	-0.6	-0.9	-0.6	-0.6	-0.3	-0.1	0.1	-0.2	-1.4	0.8	-1.2	0.8	-2.0	-0.2	0.6
Number of live births	0.6	0.8	2.1	-0.5	0.1	-0.5	-1.1	-0.8	-0.4	-0.9	-0.7	-1.0	0.2	0.9	1.2	1.5	0.1	1.3	1.4
Forced expiratory volume in 1-second (FEV1)	1.8	6.2	10.7	2.4	1.9	2.3	3.3	2.9	1.9	3.0	3.1	3.1	0.3	-2.0	-2.6	-2.0	-2.7	-2.4	-2.3
Pulse rate	0.4	0.7	3.3	-0.4	-1.8	-0.8	-0.1	-0.9	-0.6	-0.2	-0.2	-0.5	-0.1	1.1	1.5	0.8	0.5	0.9	0.6
Happiness	0.9	1.1	3.3	-1.4	-1.4	-0.8	-1.0	-1.8	-0.6	-0.5	-1.2	-1.0	-1.8	1.0	0.3	-0.1	1.0	0.4	0.9
Noisy workplace	0.5	0.6	1.6	1.2	-0.0	0.6	0.8	-0.6	0.9	1.0	1.3	1.2	-0.8	-0.5	0.1	-0.5	-0.9	-0.3	-0.8
Qualifications: A levels/AS levels or equivalent	0.5	1.0	2.7	-0.3	-1.1	-0.6	-0.7	-1.6	0.6	1.1	0.3	-0.2	-0.6	1.2	-0.6	0.8	-1.7	1.3	1.5
Serious illness, injury or assault of a close relative in last 2 years	3.1	3.6	6.1	2.0	1.6	2.4	2.1	1.5	2.5	2.2	2.1	2.0	1.0	-1.7	-1.8	-1.6	-2.0	-1.8	-1.6
Mouth/teeth dental problems: Dentures	0.3	0.4	2.1	0.2	-0.3	0.1	-0.1	0.2	-0.5	-1.0	0.2	0.4	-0.6	-0.9	0.9	-0.3	1.5	0.2	-1.0
Asthma	0.5	1.0	4.5	-0.6	-1.4	-0.8	-0.8	-0.6	0.0	-1.3	-0.9	-0.9	-0.3	0.6	1.8	0.4	2.1	1.0	0.5
Medication: Ibuprofen (e.g. Nurofen)	0.1	0.1	0.5	-0.5	-0.4	-0.6	0.4	-0.1	-0.4	-0.0	-0.4	-0.1	-0.3	0.5	0.7	-0.2	0.6	-0.1	-0.1
Medication: Cholesterol lowering	0.6	0.9	2.6	0.5	-1.4	-1.1	0.0	-0.6	-0.7	-0.9	-0.6	0.1	1.4	0.3	-1.3	-1.3	-0.1	-1.6	-1.0
Depression (self-reported)	0.2	0.2	1.4	-0.3	-0.1	0.5	-0.1	-0.3	-0.7	-0.3	0.2	0.2	-1.2	-0.3	0.1	-0.6	0.6	-0.4	-0.5
Medication: Lansoprazole	3.0	3.4	9.4	-1.5	-3.1	-2.1	-2.2	-1.9	-1.0	-2.6	-2.6	-2.0	-0.5	1.9	1.2	0.7	2.0	0.8	1.2
Prospective memory result	0.5	0.6	1.6	-0.6	0.6	-0.7	-0.7	-0.2	-1.1	-0.7	-1.3	-1.1	0.5	0.3	0.9	0.4	1.0	0.6	0.6
Lung cancer (father)	0.9	1.0	3.0	0.5	0.1	1.7	0.7	0.7	1.4	0.4	0.1	0.7	0.4	-1.6	-1.1	-1.6	-0.6	-1.3	-1.3
Illnesses of mother	0.4	0.5	1.9	-0.7	-0.9	-0.6	-0.8	-1.0	0.0	-0.5	-0.8	-0.7	0.1	1.0	0.6	0.1	1.4	0.6	0.6
Forced expiratory volume in 1-second (FEV1), Best measure	2.6	8.4	14.0	3.0	2.1	2.8	3.7	3.3	2.4	3.7	3.7	3.6	-0.2	-2.3	-3.1	-2.0	-3.5	-2.6	-2.4
Pulse wave Arterial Stiffness index	0.3	0.3	2.2	0.4	0.6	-0.6	-0.3	0.0	-1.5	0.1	-0.5	-0.4	0.7	0.6	0.5	0.5	-0.1	0.3	0.7
Impedance of arm (left)	0.3	1.3	2.5	1.5	1.0	0.5	1.1	1.2	1.4	1.4	1.6	1.3	0.4	-1.1	-1.4	-0.6	-1.6	-0.5	-0.8
Arm fat mass (right)	0.2	1.0	2.9	-1.1	-1.1	-0.3	-1.0	-0.7	-0.7	-1.4	-1.7	-1.4	-1.1	1.1	0.2	0.2	1.4	-0.1	0.8
Trunk predicted mass	0.3	1.4	5.4	-0.3	0.3	1.5	1.0	0.7	0.6	0.8	0.2	0.6	-2.3	-0.5	-2.2	-1.5	-0.3	-2.0	-0.8
Standing height	1.2	11.7	28.7	1.9	2.5	4.1	3.7	3.4	2.8	4.1	3.3	3.1	-2.0	-2.8	-5.4	-2.6	-4.4	-4.1	-2.5
Length of working week for main job	1.1	1.2	4.8	0.6	-0.7	0.4	1.0	0.0	1.1	1.1	1.2	1.0	-1.1	-0.4	-1.6	-0.6	-2.2	-1.5	-0.7
Exposure to tobacco smoke at home	0.4	0.4	1.3	-0.1	-0.3	-0.6	-0.3	-0.5	-0.5	-0.1	0.5	-0.1	1.1	0.9	0.9	1.1	-0.3	1.1	0.7
Breastfed as a baby	0.2	0.3	0.8	-0.8	-0.5	0.2	0.0	0.1	-0.0	0.0	-0.9	-0.4	0.5	-0.4	-0.0	-0.9	0.8	-0.7	-0.5
Tense / ‘highly strung’	0.8	1.3	3.4	-1.7	-0.7	-1.2	-1.1	-0.5	-1.8	-1.0	-1.4	-1.5	-0.7	1.2	0.5	1.0	0.6	0.7	1.3
Seen doctor (GP) for nerves, anxiety, tension or depression	2.3	3.6	6.9	-2.2	-1.5	-2.5	-2.1	-1.8	-2.6	-2.0	-2.2	-2.2	-0.6	2.6	0.6	1.5	0.7	1.0	2.1
Hair/balding pattern: Pattern 4	0.2	0.4	2.9	1.0	0.8	0.8	0.1	-0.0	-0.0	0.8	0.5	0.3	0.7	-0.2	-0.5	0.3	-1.7	0.3	0.3
Birth weight of first child	0.9	1.7	3.2	1.3	0.9	0.7	1.3	0.5	1.0	1.7	1.5	1.8	1.6	-0.9	-1.8	-1.1	-1.5	-1.0	-1.3
Peak expiratory flow (PEF)	0.3	0.6	1.7	0.5	-0.6	-0.1	1.0	0.5	1.1	0.8	0.7	0.7	1.1	0.1	-1.0	-0.5	-1.3	-1.1	-0.4
Pulse wave reflection index	0.3	0.4	1.1	0.3	0.4	-0.7	-0.5	0.4	-0.7	-0.4	-0.3	-0.3	0.7	0.1	1.0	0.6	0.9	0.9	0.4
Ever highly irritable/argumentative for 2 days	0.5	0.6	1.5	-1.1	-0.3	0.0	-0.7	-0.7	-1.2	-0.0	-0.5	-0.9	0.5	0.9	0.9	0.8	0.3	1.1	1.1
Loud music exposure frequency	1.0	1.1	3.4	1.8	0.5	1.2	0.8	0.6	0.5	0.6	1.6	1.6	0.8	-1.3	0.0	-0.4	-0.5	0.2	-1.4
Qualifications: O levels/GCSEs or equivalent	0.5	0.9	3.8	0.4	0.9	1.2	0.4	0.4	1.3	1.5	0.9	0.6	2.0	-0.6	-0.6	-0.2	-0.5	0.9	0.1
Mouth/teeth dental problems: Bleeding gums	1.1	1.4	3.5	-1.4	-0.7	-0.8	-1.3	-1.2	-1.9	-0.8	-1.1	-1.5	0.1	1.2	1.5	1.1	0.7	1.3	1.4
Blood clot in the leg (DVT)	1.2	1.6	6.6	0.4	-0.8	0.4	0.6	-0.0	1.2	-0.2	-0.1	1.0	-0.5	-1.0	-2.1	-2.6	0.3	-2.4	-2.0
Medication: Paracetamol	0.2	0.4	2.6	0.1	-0.6	0.8	0.8	0.8	1.6	0.0	0.4	0.5	-0.5	-0.4	0.1	-0.2	-0.1	-0.4	-0.7
Headache pain in last month	0.8	1.4	4.2	-1.3	-1.1	-1.7	-0.8	-1.4	-2.0	-1.3	-0.8	-0.9	0.2	1.7	1.2	1.1	0.5	0.4	1.0
Medication for cholesterol, blood pressure or diabetes	1.1	1.7	5.3	-1.7	0.9	0.2	-1.2	-0.2	-0.2	-0.5	-0.4	-1.3	-1.3	0.7	2.0	2.3	0.3	2.2	2.1
Glaucoma (self-reported)	0.5	0.5	2.0	0.8	1.4	0.6	0.6	1.1	-0.0	1.1	0.8	0.6	-0.5	-0.9	-0.6	-0.4	-0.2	-0.3	-0.4
Gout (self-reported)	0.1	0.2	0.4	-0.1	-0.1	-0.3	-0.3	-0.1	0.1	-0.5	-0.5	-0.5	-0.5	0.7	-0.4	0.0	0.5	-0.2	0.6
Hypothyroidism/myxoedema (self-reported)	0.9	1.8	4.9	-0.6	-0.7	0.0	-1.9	-1.9	-0.8	-1.4	-0.8	-1.1	-0.8	0.8	2.0	1.1	1.8	2.2	1.1
Medication: Amlodipine	1.1	1.5	3.5	1.4	-0.5	-0.0	1.3	0.6	1.2	1.1	0.7	1.3	-0.4	-0.7	-1.8	-1.9	-0.9	-1.9	-1.6
Medication: Ventolin 100micrograms inhaler	0.5	0.7	2.6	-1.0	-1.6	-0.2	-0.6	-0.1	-0.3	-0.8	-1.0	-0.9	0.0	0.6	0.8	0.2	1.5	0.5	0.5
Birth weight	0.7	1.5	4.8	0.7	0.5	1.2	1.6	0.9	0.5	2.2	2.0	1.8	-0.2	-0.5	-1.5	-1.0	-0.9	-0.5	-0.9
Chronic bronchitis/emphysema (mother)	0.5	0.5	2.4	-1.6	0.9	0.1	-0.7	0.0	-1.2	-0.8	-0.9	-0.8	0.6	-0.3	0.4	0.2	0.7	0.2	0.4
High blood pressure (siblings)	0.7	1.0	3.0	1.0	0.3	1.0	1.3	1.1	0.8	1.7	1.0	1.1	1.0	-0.8	-0.9	-0.7	-1.0	-0.9	-0.8
Forced vital capacity (FVC), Best measure	3.5	12.8	22.2	3.3	2.8	3.8	4.5	4.0	2.9	4.7	4.7	4.5	0.3	-3.3	-3.5	-2.7	-3.6	-3.1	-3.3
Body fat percentage	0.1	0.3	0.8	0.1	-0.9	0.2	-0.4	-0.2	-0.3	-0.8	-0.8	-0.7	-0.8	0.7	-0.4	0.3	-0.1	-0.5	0.4
Leg fat percentage (right)	0.2	0.6	1.7	0.6	-1.1	0.1	-0.7	-0.8	-0.2	-0.8	-0.5	-0.7	-0.6	1.2	-0.3	1.1	-1.3	0.0	0.8
Arm fat-free mass (right)	0.2	1.1	4.9	-0.4	0.1	1.5	0.9	0.6	0.1	0.6	0.1	0.5	-2.2	-0.4	-1.6	-1.3	-0.1	-1.8	-0.8
Exposure to tobacco smoke outside home	0.3	0.4	1.4	-0.7	-0.7	-0.4	-0.1	-0.5	0.9	-0.4	-0.1	-0.1	1.1	0.5	1.2	0.5	0.8	0.5	0.2
Comparative body size at age 10	0.8	2.1	14.6	-1.6	-0.8	0.0	-0.0	0.2	0.5	-1.0	-1.4	-0.1	-1.5	-1.0	-0.4	-2.4	3.8	-1.2	-1.5
Number of full brothers	0.3	0.3	1.2	-0.8	-0.5	-0.4	-0.6	-0.1	-0.2	-1.1	-0.8	-0.8	0.1	0.4	0.4	0.7	0.2	-0.0	0.7
Worry too long after embarrassment	1.5	2.5	4.2	-2.0	-1.8	-1.8	-1.8	-1.9	-1.4	-1.9	-2.0	-1.8	-1.2	1.5	1.3	0.8	1.2	0.7	1.1
Seen a psychiatrist for nerves, anxiety, tension or depression	1.6	2.1	6.8	-2.6	-0.6	-1.0	-1.6	-1.2	-1.6	-1.7	-1.9	-1.6	0.9	1.1	1.5	0.8	1.8	1.0	1.2
Wheeze or whistling in the chest in last year	2.3	4.2	10.3	-2.5	-3.2	-1.8	-2.0	-2.8	-1.8	-2.7	-2.2	-1.9	-1.4	2.2	1.6	1.1	1.9	0.8	1.2
Number of children fathered	5.7	6.4	11.2	3.3	2.8	2.0	2.8	3.4	1.9	2.5	3.0	3.0	0.6	-2.9	-2.1	-2.1	-1.6	-2.2	-2.8
Reason for reducing amount of alcohol drunk: Health precaution	0.8	0.9	3.6	-1.4	-1.2	-1.2	-0.4	-0.2	-0.5	-1.1	-0.9	-0.4	-1.3	0.0	0.0	-1.1	1.9	-0.6	-0.5
Age at first live birth	0.5	0.9	1.9	1.1	-0.4	0.4	1.3	0.9	0.8	1.2	1.0	1.3	0.6	-0.8	-1.0	-1.4	-0.2	-0.7	-1.3
Pulse wave peak to peak time	0.7	0.8	3.5	-0.0	-0.2	1.1	0.8	0.5	1.9	0.4	0.9	0.9	-0.7	-1.0	-0.9	-0.8	-0.4	-0.8	-1.1
Health satisfaction	1.4	1.9	3.8	-0.9	-1.4	-1.5	-1.3	-1.7	-0.7	-0.8	-1.0	-1.3	-0.7	1.9	1.6	1.7	0.4	1.8	2.0
Shortness of breath walking on level ground	3.1	3.7	9.9	-1.0	-3.0	-3.1	-2.3	-2.9	-1.5	-2.2	-2.0	-1.7	-1.1	2.0	0.8	0.4	1.8	1.0	1.4
Qualifications: College or University degree	0.2	0.6	2.2	-1.3	-0.9	-0.5	-0.7	-1.2	0.2	0.0	-0.7	-0.5	-1.5	0.8	-0.2	-0.3	1.0	0.4	0.7
Eye problems/disorders: None of the above	0.4	0.5	1.2	0.3	0.6	0.1	1.0	1.1	0.4	0.5	0.4	0.5	0.4	-0.8	-0.4	-0.9	0.1	-1.1	-0.9
Mouth/teeth dental problems: Loose teeth	0.6	0.7	3.0	0.6	-0.3	0.6	0.9	0.8	0.2	0.4	0.2	0.9	0.5	-1.1	-0.0	-1.7	0.9	-1.0	-1.5
Emphysema/chronic bronchitis	0.7	0.8	3.1	-0.3	-0.8	-0.2	1.1	0.9	-0.2	0.5	0.1	0.5	-1.8	-0.2	-1.2	-1.3	0.0	-1.4	-0.9
Medication for pain relief, constipation, heartburn	0.6	1.1	3.3	1.7	1.8	1.1	0.2	0.2	-0.3	1.5	1.6	0.7	0.2	-0.6	-0.4	0.7	-1.6	0.6	0.4
Neck or shoulder pain in last month	0.6	0.9	3.8	0.1	-1.9	-1.5	-0.6	-1.4	-1.0	-0.7	-0.5	-0.4	-1.3	1.4	0.4	0.2	-0.6	-0.2	0.4
Medication: Blood pressure	0.4	0.7	2.1	1.4	-0.6	-0.4	0.5	-0.4	-0.2	0.3	0.2	0.9	0.7	-0.2	-1.3	-1.3	0.0	-1.1	-1.2
Angina (self-reported)	0.8	1.0	2.5	-0.9	-1.4	-1.6	-1.2	-1.0	-0.7	-1.3	-1.5	-1.1	0.8	1.1	-0.2	0.1	0.7	0.1	0.7
Migraine (self-reported)	0.7	0.9	3.8	-1.4	-0.0	0.6	0.5	0.3	0.2	0.4	-0.8	0.1	-0.1	-0.8	-1.5	-1.9	0.2	-1.8	-1.0
Medication: Ibuprofen	0.1	0.1	0.3	-0.6	-0.3	-0.4	0.4	0.3	-0.4	-0.1	-0.2	0.2	0.1	-0.0	0.5	-0.3	0.5	-0.3	-0.5
Medication: Allopurinol	0.4	0.5	2.5	-0.9	0.2	-0.3	-0.0	0.3	-0.5	-1.0	-1.0	-0.5	-0.2	0.1	-0.2	-0.8	1.6	-1.0	-0.3
Medication: Omeprazole	7.1	8.4	15.1	-3.7	-3.2	-3.3	-3.0	-2.3	-2.6	-3.7	-3.9	-3.6	-1.4	2.7	2.6	1.8	2.9	1.8	2.5
Medication: Seretide 50 evohaler	2.2	2.6	5.8	-2.4	-1.4	-0.7	-1.9	-1.2	-1.2	-1.9	-1.9	-2.0	-0.8	1.2	1.6	1.2	2.2	1.5	1.4
Mean time to correctly identify matches	0.7	1.4	3.9	1.3	-0.2	1.0	1.3	0.9	1.4	1.5	0.8	1.0	-1.6	-0.4	-2.0	-1.2	-0.7	-1.1	-1.0
Heart disease (mother)	0.9	1.1	2.8	-1.4	-1.7	-1.7	-0.9	-0.9	-1.5	-1.3	-1.2	-0.9	-0.1	1.2	0.0	0.3	0.6	0.2	0.6
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.8	2.1	3.4	-1.7	-1.3	-1.8	-1.7	-1.7	-0.1	-1.8	-1.6	-1.6	-0.2	1.4	1.5	1.2	1.5	1.1	1.6
Whole body fat mass	0.1	0.5	2.6	-0.2	-0.9	0.3	-0.2	-0.1	-0.1	-0.7	-0.9	-0.6	-1.6	0.5	-0.9	-0.3	0.1	-1.1	0.0
Leg fat mass (right)	0.1	0.3	1.2	0.2	-1.1	0.3	-0.3	-0.3	0.1	-0.6	-0.7	-0.6	-1.1	0.7	-0.6	0.2	-0.4	-0.6	0.3
Arm predicted mass (right)	0.2	0.9	5.4	-0.7	-0.1	1.4	0.6	0.4	-0.1	0.3	-0.2	0.2	-2.3	-0.3	-1.4	-1.0	0.1	-1.6	-0.5
Pulse rate, automated reading	0.6	1.9	4.1	-0.9	-1.8	-1.2	-0.9	-1.5	-1.7	-0.8	-0.4	-1.1	-0.2	1.9	2.0	1.9	0.3	1.9	1.5
Alcohol intake frequency.	0.4	0.9	2.6	-1.2	-0.1	-0.0	-1.2	-0.9	-1.1	-1.6	-1.0	-1.2	-1.0	0.6	1.1	1.0	0.7	0.4	0.7
Comparative height size at age 10	1.0	5.5	23.1	-0.1	-0.6	0.8	1.6	1.2	1.4	1.3	0.6	1.3	-4.1	-1.4	-4.8	-3.1	-1.7	-4.4	-2.0
Number of full sisters	1.9	2.4	7.8	1.6	1.3	1.9	1.6	1.4	0.8	1.5	1.7	1.4	-0.6	-1.3	-1.9	-0.3	-2.8	-1.5	-1.0
Suffer from ‘nerves’	0.7	1.1	3.8	-0.7	-0.7	-0.8	-0.8	-0.5	-1.3	-1.5	-0.9	-1.1	0.3	0.8	1.9	0.8	1.5	1.1	0.7
Overall health rating	0.6	1.2	2.4	-1.5	-1.6	-1.0	-0.8	-1.3	-1.4	-1.3	-1.0	-0.7	-0.4	1.4	1.1	0.4	1.5	0.6	0.6
Chest pain or discomfort	5.1	7.3	13.9	-3.4	-3.5	-3.4	-2.8	-2.5	-1.6	-3.7	-3.2	-3.0	-2.0	2.8	2.0	1.7	2.6	1.4	2.1
Had major operations	0.3	0.4	1.3	-0.1	-1.1	-0.8	-0.2	-0.3	-0.1	-0.1	-0.7	-0.4	0.1	1.1	0.4	0.3	1.0	0.5	0.5
Age at last live birth	0.2	0.3	1.1	1.0	0.1	0.4	0.5	0.1	-0.0	1.0	1.0	0.8	0.8	-0.3	-0.2	-0.1	-0.4	0.6	-0.4
Family relationship satisfaction	4.4	5.4	10.5	-3.1	-2.0	-2.2	-2.7	-2.9	-1.4	-2.6	-2.5	-2.3	0.2	2.0	2.7	1.3	3.2	2.2	2.0
Leg pain on walking	1.0	1.3	5.1	-0.4	-2.3	-1.9	-0.8	-1.0	-0.2	-1.0	-1.5	-1.1	-1.0	1.8	-0.1	0.3	-0.4	-0.6	0.8
Qualifications: NVQ or HND or HNC or equivalent	3.1	3.7	6.6	2.0	2.1	2.6	2.3	2.5	2.1	2.1	2.0	1.9	0.8	-2.2	-0.6	-0.9	-2.1	-1.2	-1.7
Commuting to job workplace: Car/motor vehicle	0.2	0.3	3.0	0.1	-0.6	0.0	-0.0	-0.1	0.4	0.1	-0.0	0.2	1.7	0.1	0.7	0.1	0.3	0.3	-0.0
Illness, injury, bereavement, stress in last 2 years	3.1	3.8	7.7	-2.8	-1.2	-1.6	-2.4	-1.8	-2.0	-2.7	-2.2	-2.2	-0.5	1.2	2.1	1.4	2.5	1.4	1.4
Medication: Aspirin	0.5	0.7	2.6	-0.8	-1.6	-0.9	-0.4	-0.6	-0.2	-0.8	-1.1	-0.5	1.6	0.9	-0.3	-0.5	1.1	-0.1	-0.0
Supplements: Vitamin C	0.9	1.1	2.6	-1.0	-0.5	-0.2	-1.6	-1.6	-0.9	-1.4	-0.4	-0.8	-0.3	0.4	1.5	1.0	1.2	1.6	0.6
Knee pain experienced in last month	0.5	0.8	2.7	0.2	0.0	-0.3	-0.8	-1.0	0.0	-0.2	-0.1	-0.6	-0.3	0.9	1.0	1.6	-1.5	1.4	1.3
Hypertension (Self-reported)	0.3	0.8	2.7	1.0	-1.0	-0.3	0.9	0.0	0.5	0.1	-0.0	0.8	0.3	-0.1	-1.1	-1.6	0.3	-1.6	-1.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.7	0.9	3.6	0.1	0.5	-0.0	-0.5	0.9	0.8	-0.3	-0.0	-0.6	1.6	0.5	1.3	1.9	-0.6	1.4	1.0
Illnesses of father: Heart disease	0.4	0.5	2.4	0.2	-0.3	-0.7	-0.3	-0.4	-0.2	-0.4	0.6	-0.4	-0.9	0.6	0.4	1.6	-1.6	0.5	0.7
Illnesses of siblings: Diabetes	0.5	0.7	2.2	-1.1	-0.8	-0.2	-0.2	-0.9	0.8	-0.8	-0.8	-0.4	-1.5	-0.1	0.2	-0.8	1.4	-0.5	-0.5
Smoking status: Previous	0.8	1.2	2.6	-1.2	-0.5	-1.0	-1.4	-0.6	-0.1	-1.3	-1.5	-1.6	-0.0	1.1	0.9	1.0	0.7	1.0	1.5
Forced expiratory volume in 1-second (FEV1), predicted	2.7	5.6	10.9	1.5	2.1	2.4	3.3	2.5	2.3	2.6	2.9	3.0	-1.3	-2.3	-2.4	-2.2	-1.0	-2.5	-2.5
Whole body fat-free mass	0.2	1.2	6.1	-0.7	0.1	1.4	0.8	0.7	0.4	0.4	-0.2	0.3	-2.5	-0.5	-1.7	-1.5	0.5	-1.8	-0.8
Leg fat-free mass (right)	0.2	1.2	6.4	-1.5	-0.1	0.8	0.1	0.5	0.2	-0.4	-0.9	-0.4	-2.5	-0.5	-0.7	-1.4	2.0	-1.2	-0.5
Arm fat percentage (left)	0.5	2.2	5.5	-1.4	-1.6	-1.0	-1.6	-1.2	-0.9	-2.1	-2.2	-1.8	-1.0	1.5	1.0	0.5	2.3	0.6	1.1
Average weekly red wine intake	0.4	0.6	1.8	0.5	-0.0	0.8	0.6	-0.1	0.9	1.3	0.9	0.9	1.2	-0.4	-0.7	-0.9	-0.8	-0.4	-0.5
Handedness (chirality/laterality): Left-handed	0.3	0.4	2.1	0.8	1.0	0.6	0.4	0.4	-0.4	0.6	0.8	0.7	1.5	-0.3	0.3	0.1	0.3	0.3	-0.3
Mood swings	0.3	0.6	1.9	-0.7	-1.2	-0.2	0.9	0.4	0.5	-0.0	-0.4	-0.1	-1.3	0.8	-1.1	-0.5	-0.5	-1.4	-0.2
Loneliness, isolation	4.2	5.8	8.9	-2.4	-2.1	-2.5	-2.7	-2.8	-2.7	-2.7	-2.5	-2.8	-1.5	3.0	2.1	2.4	0.7	1.9	2.7
Long-standing illness, disability or infirmity	4.6	7.1	12.2	-2.5	-2.3	-2.2	-3.3	-3.0	-2.3	-2.7	-3.0	-2.8	-0.5	2.6	3.0	1.8	3.5	3.2	2.5
Ever had bowel cancer screening	1.3	1.6	4.6	-0.8	-1.2	-1.7	-1.1	-1.0	-0.4	-0.7	-0.6	-1.1	0.3	1.6	1.3	2.0	0.5	2.1	1.6
Diabetes diagnosed by doctor	3.7	6.1	14.4	-2.8	-1.2	-2.2	-2.6	-2.4	-2.9	-2.8	-3.0	-2.9	0.1	2.0	2.8	1.5	3.8	2.2	1.9
Ever had stillbirth, spontaneous miscarriage or termination	0.5	0.6	2.5	-1.4	0.1	-0.2	-0.6	0.1	-1.0	-0.9	-1.1	-0.8	-1.6	0.1	-0.1	-0.1	0.8	-0.4	0.3
Friendships satisfaction	3.8	4.7	8.1	-2.2	-2.4	-2.3	-2.5	-2.8	-0.3	-1.9	-2.4	-2.3	0.2	2.3	2.5	1.2	2.8	2.1	2.3
Qualifications: nursing, teaching	0.4	0.6	1.2	-0.4	0.9	0.7	0.7	0.9	0.7	0.9	0.1	0.3	1.0	-0.9	-1.1	-1.0	-0.5	-0.8	-0.4
Commuting to job workplace: Walk	0.3	0.3	3.4	0.2	0.4	0.0	0.0	-0.0	0.1	0.1	-0.0	0.1	-1.8	-0.3	-1.0	-0.3	-0.7	-0.5	-0.1
Eye problems/disorders: Cataract	0.5	0.6	2.3	0.8	-1.5	-0.2	0.3	-0.6	0.8	0.4	0.3	0.5	-0.3	0.8	-1.3	-0.2	-1.4	-0.4	-0.1
Mouth/teeth dental problems: Mouth ulcers	0.7	1.0	7.8	-0.8	-1.2	-0.1	-0.2	-0.2	0.5	-0.9	-1.2	-0.8	0.6	0.4	1.6	-0.3	2.8	0.8	0.0
Medication for cholesterol	0.7	1.0	3.0	1.0	1.6	0.8	0.7	1.3	1.0	0.8	1.7	1.0	-0.4	-1.7	0.7	0.2	0.0	0.4	-0.7
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.2	0.2	0.6	-0.1	0.7	-0.3	0.6	0.6	0.3	-0.0	0.3	0.5	0.5	-0.5	0.4	-0.1	0.0	-0.0	-0.8
Back pain experienced in last month	0.2	0.3	1.6	-0.2	-0.6	-0.9	0.2	-0.2	-0.7	-0.5	-0.3	0.1	-1.3	0.5	-0.4	-0.3	-0.2	-0.8	-0.2
Mineral and other dietary supplements	1.1	1.5	2.7	1.1	0.7	0.9	1.5	1.3	0.7	0.9	1.1	1.3	1.2	-1.6	-0.9	-1.4	-0.8	-1.6	-1.6
Breast cancer (self-reported)	0.3	0.3	2.8	0.8	-0.4	-0.4	-0.4	-0.4	0.1	-0.1	0.1	-0.0	0.8	0.4	-0.4	0.6	-1.7	-0.2	0.2
Asthma (self-reported)	0.7	1.4	5.2	-0.8	-1.4	-0.8	-1.0	-0.8	0.0	-1.4	-1.1	-1.1	-0.3	0.9	2.1	0.7	2.3	1.4	0.8
Osteoporosis (self-reported)	0.3	0.4	2.1	-0.2	0.9	-0.0	-0.6	-0.8	0.4	1.1	0.1	-0.1	-0.2	0.1	0.3	0.6	-0.1	1.5	1.0
Osteoarthritis (self-reported)	1.4	1.9	4.5	-0.6	-1.1	-1.6	-1.4	-1.7	-0.5	-1.4	-1.4	-1.5	-0.3	2.1	0.8	1.7	0.4	1.5	1.8
Medication: Aspirin	0.5	0.6	2.2	-0.1	-0.8	0.3	0.6	0.4	0.8	0.0	-0.2	0.5	1.5	-0.3	-0.8	-1.4	0.6	-1.0	-1.0
Medication: Gliclazide	0.5	0.6	2.8	-0.6	0.0	-0.2	-0.4	-0.1	-0.7	-1.0	-0.7	-0.5	1.7	0.2	0.9	-0.1	1.7	0.3	-0.0
Illnesses of father: None of the above (group 1)	0.4	0.5	1.7	0.7	0.8	0.4	0.3	0.5	-0.2	-0.1	0.1	0.7	1.3	-0.8	-0.1	-1.2	1.1	-0.7	-1.0
Smoking status: Current	0.4	0.7	1.6	1.0	-0.4	0.3	1.2	0.5	0.7	1.0	1.3	1.3	0.3	-0.7	-0.1	-0.6	-0.8	-0.6	-1.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.9	1.9	4.1	2.0	1.7	1.4	1.6	1.7	0.8	1.7	2.0	1.8	1.1	-1.4	0.1	-0.4	-1.1	-0.3	-1.1
Whole body water mass	0.2	1.0	5.5	-0.8	0.1	1.2	0.6	0.6	0.2	0.3	-0.3	0.2	-2.3	-0.4	-1.5	-1.3	0.6	-1.6	-0.6
Leg predicted mass (right)	0.2	1.2	6.4	-1.6	-0.3	0.7	0.0	0.4	0.1	-0.5	-1.0	-0.5	-2.5	-0.3	-0.7	-1.3	2.0	-1.2	-0.5
Arm fat mass (left)	0.2	1.0	2.6	-1.1	-1.1	-0.1	-0.9	-0.7	-0.5	-1.3	-1.6	-1.2	-1.3	0.9	0.1	0.0	1.6	-0.1	0.6
Number of self-reported non-cancer illnesses	1.3	2.2	9.6	-1.7	-2.0	-1.5	-1.0	-1.3	-0.6	-1.7	-2.0	-1.3	0.5	1.3	1.6	-0.2	3.1	0.8	0.3
Average weekly champagne plus white wine intake	0.2	0.3	1.9	-1.4	-0.4	0.5	0.1	0.2	0.4	0.3	-0.7	-0.4	0.4	-0.2	-0.1	-0.9	1.0	-0.0	0.0
Miserableness	0.3	0.6	1.8	-0.7	-0.4	-0.3	1.0	0.9	0.6	0.3	-0.5	0.1	-1.2	-0.3	-0.4	-1.3	0.8	-1.2	-0.9
Guilty feelings	1.3	1.9	4.3	-1.4	-1.9	-1.8	-1.7	-2.1	-0.6	-1.7	-1.7	-1.5	-1.2	1.7	0.3	0.5	0.3	0.1	1.1
Wears glasses or contact lenses	0.9	1.0	3.2	0.1	0.2	0.4	0.9	1.0	1.4	1.1	0.1	1.0	-0.2	-1.2	-1.4	-1.8	0.8	-1.1	-1.2
Ever taken oral contraceptive pill	0.4	0.4	2.0	0.6	-0.2	0.1	-0.5	-0.6	-0.4	-0.8	0.3	-0.2	0.7	0.3	1.4	1.1	0.4	1.1	0.2
Hearing aid user	0.2	0.2	2.0	0.2	-0.0	0.5	0.1	0.0	0.1	0.3	0.4	0.3	1.4	-0.2	0.3	0.3	0.1	0.8	-0.1
Mother’s age at death	0.8	1.0	4.0	0.6	2.0	1.2	0.5	0.6	-0.6	1.0	1.1	0.3	0.1	-0.2	1.0	1.5	-1.0	1.5	0.6
Financial situation satisfaction	0.4	0.5	1.8	-0.9	-1.0	-0.8	-0.4	-0.3	0.0	-0.1	-0.7	-0.4	-1.4	0.5	0.7	-0.2	1.1	0.2	0.4
Tinnitus: Yes, now most or all of the time	1.6	1.9	5.0	1.6	1.8	2.0	0.9	0.9	1.0	2.2	2.2	1.4	0.9	-0.5	-0.7	0.2	-2.0	0.3	0.1
Commuting to job workplace: Public transport	1.3	1.5	4.2	-0.2	-1.4	-2.1	-1.0	-1.3	-1.2	-1.5	-1.6	-1.6	-0.9	1.7	0.4	0.5	1.3	0.2	0.9
Eye problems/disorders: Glaucoma	0.4	0.5	2.6	0.5	1.6	0.4	-0.5	0.1	-0.6	0.1	0.2	-0.4	0.3	-0.1	0.6	1.1	-0.2	1.0	0.8
Medication: Blood pressure	0.1	0.2	2.7	-0.1	-0.6	0.2	-0.0	-0.5	-0.3	0.1	-0.3	-0.0	1.6	0.5	0.1	-0.1	0.2	0.2	0.0
Pain type(s) experienced in last month: Hip pain	0.7	0.9	2.8	0.1	-1.5	-1.1	0.5	0.5	0.6	-0.3	-0.6	0.1	-0.9	0.3	-1.7	-1.3	0.4	-1.6	-0.8
Supplements: Fish oil (including cod liver oil)	0.2	0.3	1.0	-0.6	0.2	-0.1	-0.5	-0.4	-0.2	0.2	-0.2	-0.3	-1.0	0.8	-0.5	0.6	-0.5	0.5	0.9
High cholesterol (Self-reported)	0.4	0.7	2.7	-0.0	-1.6	-1.2	-0.3	-0.9	-0.6	-1.0	-1.4	-0.8	1.0	1.1	-0.4	-0.4	-0.2	-1.0	0.0
Medication: Bendroflumethiazide	0.9	1.4	3.0	1.7	0.9	1.7	1.4	1.1	1.2	1.4	1.1	1.4	0.9	-1.3	-0.6	-0.9	-0.3	-0.5	-1.4
Medication: Paracetamol	0.4	0.6	3.1	-0.2	0.0	1.0	0.9	1.1	1.8	0.1	0.4	0.7	-0.4	-1.0	0.4	-0.5	0.5	-0.5	-1.0
Medication: Lisinopril	0.3	0.4	1.7	1.3	0.0	0.5	0.3	0.0	1.0	0.8	0.9	0.9	-0.1	-0.2	-0.1	0.0	-0.9	-0.1	-0.2
Medication: Atorvastatin	0.3	0.3	1.3	0.5	0.2	-0.2	-0.4	-0.1	-1.0	-0.6	-0.1	-0.4	1.0	0.2	-0.1	0.9	-1.1	0.2	0.4
Illnesses of father: High blood pressure	0.2	0.3	1.3	-0.2	-0.3	0.6	0.5	0.8	1.1	0.6	0.4	0.2	0.6	-0.5	0.7	-0.2	0.9	0.1	0.0
Alcohol drinker status: Never	0.3	0.3	1.5	-0.7	0.2	-0.1	-0.6	0.0	0.4	-0.8	-0.8	-0.7	0.1	0.2	0.6	0.1	1.2	0.5	0.4
Ever smoked	0.2	0.4	2.0	-0.1	-1.4	-0.9	-0.4	-0.5	0.6	-0.6	-0.4	-0.4	0.7	0.7	0.9	0.3	0.5	0.6	0.3
Basal metabolic rate	0.2	1.1	5.9	-0.7	0.0	1.3	0.6	0.7	0.3	0.3	-0.3	0.2	-2.4	-0.4	-1.6	-1.4	0.5	-1.7	-0.6
Leg fat percentage (left)	0.2	0.9	2.2	0.2	-1.4	-0.3	-1.0	-1.1	-0.6	-1.2	-1.0	-1.1	-0.6	1.5	0.0	1.3	-0.9	0.2	1.1
Arm fat-free mass (left)	0.2	1.1	4.3	-0.3	0.0	1.4	0.9	0.7	0.0	0.5	0.0	0.4	-2.1	-0.4	-1.7	-1.1	-0.5	-1.9	-0.7
Number of operations (self-reported)	0.6	0.9	6.0	0.9	-2.4	-0.7	0.0	-0.5	0.8	0.3	0.2	-0.0	1.3	1.3	0.4	0.8	-0.4	0.9	0.5
Average weekly beer plus cider intake	0.3	0.4	1.6	-0.3	-0.8	-0.2	0.6	0.7	1.0	0.2	0.1	0.3	0.2	-0.2	-1.0	-0.7	-0.9	-1.3	-0.5
Irritability	0.2	0.4	1.0	-0.4	-0.3	0.1	-0.8	-0.9	0.8	0.6	0.2	-0.2	0.1	0.6	-0.1	0.8	-0.7	0.9	1.0
Risk taking	0.5	0.7	2.2	0.9	0.9	1.0	0.5	0.7	0.6	1.0	0.1	0.3	0.7	-0.4	-1.3	-0.7	-1.5	-0.8	-0.2
Ever had prostate specific antigen (PSA) test	1.4	1.7	4.4	-0.4	-0.8	-1.6	-1.4	-1.0	-0.8	-2.1	-1.1	-1.4	1.1	1.6	1.3	2.0	-0.0	0.9	1.2
Fractured/broken bones in last 5 years	0.6	0.8	3.6	0.1	1.1	0.9	-0.7	0.2	0.3	0.2	0.3	-0.2	1.7	-0.3	1.4	1.0	0.5	1.9	0.8
Age started oral contraceptive pill	0.2	0.2	0.9	0.7	-0.4	0.3	0.1	0.1	-0.1	0.6	0.4	0.2	0.9	0.5	0.2	0.2	-0.1	0.7	0.3
Diastolic blood pressure, automated reading	0.1	0.3	1.2	0.1	-0.4	-0.4	-0.1	-0.1	-1.1	-0.1	-0.6	-0.8	0.2	0.7	0.7	0.8	-0.1	0.3	0.8
Ever depressed for a whole week	0.3	0.4	1.5	-0.4	-0.1	-0.8	-0.5	-0.6	-0.9	-0.6	-0.5	-0.6	-1.2	0.5	0.0	0.6	-0.6	-0.3	0.4
Unable to work because of sickness or disability	1.8	2.4	5.7	-2.4	-1.2	-1.4	-1.7	-1.1	-2.1	-2.3	-1.7	-1.6	0.3	1.1	1.8	0.6	2.0	0.6	0.9
Commuting to job workplace: Cycle	4.2	5.1	11.0	-1.6	-2.9	-2.0	-2.5	-3.3	-1.6	-1.7	-2.0	-2.3	-0.8	2.8	2.2	2.3	1.8	2.6	2.6
Myopia	2.0	2.9	10.6	-0.0	-0.7	-0.1	2.0	1.5	2.1	0.9	0.6	1.8	0.1	-1.7	-1.9	-3.2	1.3	-2.5	-2.6
Vascular/heart problems diagnosed by doctor	0.3	0.8	2.9	-0.7	1.1	0.7	-0.7	0.1	-0.0	0.2	0.3	-0.5	-0.7	0.0	1.4	1.6	-0.4	1.7	1.4
Cholesterol lowering medication	3.2	4.7	7.6	-2.3	-2.3	-2.1	-2.3	-2.7	-2.6	-2.4	-2.7	-2.5	0.6	2.8	1.8	1.8	1.2	1.6	2.1
Medication: Omeprazole (e.g. Zanprol)	6.6	8.0	16.5	-3.7	-3.6	-3.5	-2.8	-2.1	-2.5	-3.9	-4.1	-3.4	-1.3	2.4	2.1	1.1	3.0	1.1	1.9
Pain experienced in last month	1.1	1.8	4.0	1.0	1.4	1.9	1.4	1.8	2.0	1.3	0.9	1.1	0.2	-1.8	-1.0	-1.3	0.4	-0.6	-1.5
Supplements: Calcium	1.5	1.6	2.9	-1.1	-1.3	-1.6	-1.3	-1.2	-1.4	-0.9	-1.7	-1.4	0.8	1.5	0.9	0.6	1.4	1.0	1.4
Basal cell carcinoma (self-reported)	2.2	2.6	5.5	-1.2	-1.4	-1.5	-1.7	-1.1	-2.1	-1.0	-1.8	-2.0	0.5	2.0	1.5	2.2	-0.1	1.7	2.4
Heart attack/myocardial infarction (self-reported)	0.4	0.6	3.2	0.1	-1.2	-1.8	-0.1	-0.3	-0.1	-1.3	-0.2	-0.1	1.2	0.5	0.0	-0.1	1.0	-0.0	-0.3
Deep venous thrombosis (DVT) (self-reported)	1.1	1.4	5.9	0.1	-0.6	0.4	0.5	0.1	1.1	-0.3	-0.3	0.8	-0.4	-0.9	-2.0	-2.4	0.3	-2.3	-1.8
Heart disease (siblings)	0.2	0.2	1.6	0.2	-0.0	0.2	0.5	0.2	-0.5	0.8	0.2	0.1	-0.5	0.5	-0.1	0.5	-1.3	-0.0	0.4
Alcohol drinker status: Previous	1.2	1.3	5.5	0.0	2.0	2.3	1.1	1.0	0.7	1.4	0.8	0.9	1.6	-1.1	-0.5	-0.9	-0.7	-0.6	-0.6
Pack years of smoking	1.4	2.1	4.8	1.0	0.2	1.4	1.6	1.2	0.3	1.0	1.0	1.4	1.2	-1.2	-2.2	-2.0	-1.4	-2.2	-1.7
Impedance of whole body	1.0	4.9	19.7	3.0	1.6	1.5	2.1	1.9	1.9	2.5	3.0	2.3	1.1	-1.6	-2.3	-0.2	-4.4	-1.2	-1.3
Leg fat mass (left)	0.1	0.5	1.6	-0.2	-1.3	0.1	-0.6	-0.5	-0.3	-0.9	-1.0	-0.9	-1.2	1.0	-0.5	0.3	-0.2	-0.5	0.6
Arm predicted mass (left)	0.2	1.2	4.2	-0.3	0.1	1.4	0.9	0.7	0.1	0.5	-0.0	0.4	-2.0	-0.5	-1.9	-1.3	-0.3	-2.1	-0.8