TWAS hub - PPP1R32

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Testis	0.214	0.091	0.0057	-0.006	NA	0.038	NA	0.024	0.80	NA	0.0088	NA	0.03000
2	GTEx	Uterus	0.659	0.125	0.0015	-0.015	NA	0.071	NA	0.141	0.98	NA	0.0150	NA	0.00088

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
LDL Cholesterol	12.8	20.2	40.2	0.5	-6.3
Number of live births	11.6	16.4	26.7	2.5	-5.2
HDL Cholesterol	10.0	16.6	32.7	0.7	-5.7
Respiratory disease	9.2	20.4	34.4	2.5	-5.9
Medication: Levothyroxine sodium	9.2	15.6	26.7	2.1	-5.2
Triglycerides	8.1	13.2	26.4	-0.3	5.1
Hypothyroidism (self reported)	7.6	17.5	34.9	-0.2	-5.9
Asthma (self-reported)	7.4	14.7	25.9	1.9	-5.1
Pulse rate, automated reading	7.3	23.4	45.4	1.2	6.7
Fasting Glucose	7.0	8.4	16.8	0.2	-4.1
Hypothyroidism/myxoedema (self-reported)	6.4	12.4	24.5	0.6	-4.9
Asthma	6.2	12.2	22.0	1.6	-4.7
Blood Red Count	6.0	57.6	108.2	2.7	10.4
Blood Eosinophil Count	5.7	43.9	85.2	-1.6	-9.2
Blood Platelet Count	5.5	63.8	127.7	-0.1	11.3
Ever unenthusiastic/disinterested for a whole week	5.4	6.6	12.8	-0.7	3.6
Allergy	5.3	12.1	13.2	-3.3	3.6
High cholesterol (Self-reported)	5.0	8.9	15.8	1.4	-4.0
Heel bone mineral density (BMD) T-score, automated (left)	4.8	10.9	18.4	-1.9	4.3
Hayfever/allergic rhinitis (self-reported)	4.7	6.2	7.4	2.2	-2.7
Wheeze or whistling in the chest in last year	4.7	8.4	11.8	2.2	-3.4
Heel bone mineral density (BMD) T-score, automated (right)	4.3	9.8	16.7	-1.7	4.1
Medication: Simvastatin	4.3	6.3	12.5	-0.0	-3.5
Medication: Atenolol	3.9	4.9	6.6	-1.8	2.6
Commuting to job workplace: Car/motor vehicle	3.9	4.4	7.8	1.0	-2.8
Supplements: Fish oil (including cod liver oil)	3.8	4.9	9.6	-0.5	-3.1
Crohns Disease (2012)	3.7	6.0	9.7	-1.5	3.1
Emphysema/chronic bronchitis	3.7	4.1	6.8	2.6	-1.2
Average weekly spirits intake	3.6	4.5	8.4	0.8	-2.9
Bipolar Disorder (2018)	3.5	5.5	11.0	-0.2	3.3
Hair/balding pattern: Pattern 2	3.5	4.5	7.3	2.7	-1.3
Osteoporosis (self-reported)	3.4	4.2	8.3	0.5	-2.9
Hair/balding pattern: Pattern 3	3.2	4.7	9.1	-3.0	-0.6
Ovarian Cancer	3.1	4.1	7.7	0.7	-2.8
Pulse rate	3.1	5.2	10.2	-0.4	3.2
Crohns Disease (2017)	3.0	6.5	13.0	0.3	3.6
Townsend deprivation index at recruitment	3.0	4.2	7.7	0.8	2.8
Tense / ‘highly strung’	3.0	4.9	9.7	-0.5	3.1
Seen doctor (GP) for nerves, anxiety, tension or depression	3.0	4.6	8.9	-0.5	3.0
Irritability	3.0	5.0	9.6	-0.7	3.1
Fractured/broken bones in last 5 years	3.0	3.8	7.3	0.6	-2.7
Falls in the last year	2.9	3.9	7.7	0.4	-2.8
Number of children fathered	2.9	3.3	6.6	0.1	-2.6
Reason for reducing amount of alcohol drunk: Health precaution	2.9	3.4	4.7	-1.5	2.2
Ever depressed for a whole week	2.9	3.6	7.1	-0.2	2.7
Rheumatoid Arthritis	2.8	3.9	7.3	0.7	-2.7
Blood White Count	2.8	20.6	41.1	-0.2	-6.4
Other serious medical condition/disability diagnosed by doctor	2.8	3.6	5.4	-2.3	-1.4
Qualifications: NVQ or HND or HNC or equivalent	2.8	3.4	5.3	1.2	-2.3
Qualifications: CSEs or equivalent	2.7	3.6	4.5	1.6	-2.1
Medication: Lisinopril	2.7	3.5	7.0	-0.1	2.6
Exposure to tobacco smoke outside home	2.6	3.4	5.0	2.2	-1.4
Hearing aid user	2.6	2.9	5.8	0.2	-2.4
Seen a psychiatrist for nerves, anxiety, tension or depression	2.5	3.3	5.7	-0.9	2.4
Hayfever, allergic rhinitis or eczema	2.4	5.3	6.3	2.5	-2.1
Medication: Ventolin 100micrograms inhaler	2.4	3.0	4.0	2.0	-1.4
Heel T-Score	2.3	18.5	37.1	0.0	6.1
Type 2 Diabetes (T2D) (2018)	2.3	4.3	6.0	1.6	-2.5
Qualifications: nursing, teaching	2.3	3.5	5.9	-2.4	1.1
Basal cell carcinoma (self-reported)	2.3	2.7	5.5	0.2	-2.3
Mouth/teeth dental problems: Dentures	2.2	3.7	4.7	1.6	-2.2
Illnesses of mother	2.2	2.7	5.1	2.3	-0.5
Exposure to tobacco smoke at home	2.2	2.5	2.9	-1.4	-1.7
Mouth/teeth dental problems: Mouth ulcers	2.2	3.5	6.7	0.5	2.6
Average weekly champagne plus white wine intake	2.2	3.0	6.0	0.2	2.4
Commuting to job workplace: Public transport	2.2	2.6	4.0	-2.0	1.1
Bipolar Disorder or Schizophrenia	2.1	5.2	7.2	1.8	2.7
Heart attack	2.1	2.7	2.8	-1.6	-1.7
Blood clot in the leg (DVT)	2.1	2.8	5.3	-0.5	-2.3
Heart attack/myocardial infarction (self-reported)	2.1	2.7	4.0	-1.2	-2.0
Deep venous thrombosis (DVT) (self-reported)	2.1	2.6	4.9	-0.6	-2.2
Alzheimer’s Disease (in father)	2.0	2.2	2.9	-1.2	1.7
HbA1C	2.0	2.2	4.4	-0.0	-2.1
Chronotype (morning person)	2.0	4.7	9.2	0.4	-3.0
Hair/balding pattern: Pattern 4	2.0	4.7	9.5	-0.1	-3.1
Medication: Omeprazole	2.0	2.4	3.4	-1.2	1.9
Number of full sisters	1.9	2.3	2.5	-1.4	1.6
Long-standing illness, disability or infirmity	1.9	3.0	5.9	0.0	-2.4
Mineral and other dietary supplements	1.9	2.5	4.7	0.6	2.2
Diastolic blood pressure, automated reading	1.9	5.8	8.4	-1.8	2.9
Myopia	1.9	2.8	3.2	-1.5	1.8
Schizophrenia vs Biploar Disorder	1.8	2.4	4.6	-0.4	-2.1
Lupus	1.8	2.7	3.2	1.4	-1.8
Diverticular disease/diverticulitis (self-reported)	1.8	2.1	3.9	-0.5	2.0
Nervous feelings	1.8	3.3	5.2	-1.2	2.3
Diabetes (self-reported)	1.8	2.8	3.5	1.9	-1.4
Cholesterol lowering medication	1.8	2.7	5.3	-0.3	-2.3
Schizophrenia (2014)	1.7	3.8	5.0	1.6	2.2
Taking other prescription medications	1.7	2.6	4.8	0.5	-2.2
Age when periods started (menarche)	1.7	4.2	8.2	2.9	-0.3
Chronic bronchitis/emphysema (father)	1.7	2.0	4.0	0.1	-2.0
Neuroticism score	1.7	3.6	7.0	-0.5	2.6
Diabetes diagnosed by doctor	1.7	2.9	3.5	1.9	-1.5
Number of treatments/medications taken	1.6	2.9	5.8	0.2	-2.4
Had other major operations	1.6	1.9	3.1	-0.9	1.8
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.6	1.8	3.2	0.7	-1.8
Illnesses of father: High blood pressure	1.6	1.9	2.9	1.0	-1.7
Allergy or Eczema	1.5	4.1	6.5	1.3	-2.6
Vitamin and mineral supplements	1.5	2.1	4.2	0.1	2.0
Multivitamins +/- minerals	1.5	1.9	3.7	-0.2	-1.9
Chronic bronchitis/emphysema (mother)	1.5	1.8	3.5	-1.9	0.3
Angina (self-reported)	1.5	2.0	3.3	-1.8	0.8
Medication: Seretide 50 evohaler	1.5	1.7	1.9	1.2	-1.4
Osteoarthritis (self-reported)	1.5	1.9	2.0	-1.4	1.3
Miserableness	1.5	2.7	4.9	0.7	2.2
Irritable Bowel Disease (IBD)	1.4	3.4	6.4	0.7	2.5
Supplements: Zinc	1.4	1.5	2.8	-1.7	-0.4
High blood pressure (mother)	1.4	1.9	2.9	-1.7	-1.0
Had major operations	1.4	1.7	3.3	1.8	0.2
Number of self-reported non-cancer illnesses	1.4	2.4	4.2	0.8	-2.0
Worry (Nagel 2018)	1.3	2.7	5.1	-0.6	2.3
Maternal smoking around birth	1.3	1.9	3.4	0.6	-1.8
Illnesses of siblings	1.3	1.8	3.1	-1.8	-0.6
Worrier / anxious feelings	1.3	2.5	3.7	1.2	1.9
Headache pain in last month	1.3	2.2	3.9	0.7	-2.0
Gout (self-reported)	1.3	1.7	1.8	1.3	1.3
Mouth/teeth dental problems: Loose teeth	1.3	1.5	2.0	-1.0	1.4
Medication for pain relief, constipation, heartburn	1.3	2.2	4.2	-0.3	2.1
Neck or shoulder pain in last month	1.3	1.8	2.3	1.1	-1.5
Age at last live birth	1.3	2.0	2.1	1.5	-1.3
Average weekly beer plus cider intake	1.3	1.9	2.2	-1.5	1.3
Age started oral contraceptive pill	1.3	1.7	2.2	-1.5	1.1
Age at First Birth	1.2	1.7	3.3	0.1	1.8
Type 2 Diabetes (T2D) (2012)	1.2	1.4	2.2	-1.5	-0.7
Angina	1.2	1.6	2.4	-1.6	0.9
Medication: Cholesterol lowering	1.2	1.9	3.7	0.3	-1.9
Migraine (self-reported)	1.2	1.6	3.1	1.8	-0.1
Ever taken oral contraceptive pill	1.2	1.4	2.4	-1.5	0.6
Mother’s age at death	1.2	1.4	2.9	-0.2	1.7
Medication: Omeprazole (e.g. Zanprol)	1.2	1.4	1.8	-1.0	1.4
Schizophrenia (2018)	1.1	2.3	3.7	1.9	0.9
Relative age voice broke	1.1	1.7	3.0	1.7	0.7
Prospective memory result	1.1	1.4	2.7	0.3	-1.6
Ever highly irritable/argumentative for 2 days	1.1	1.4	2.7	0.0	1.6
Medication: Gliclazide	1.1	1.3	1.3	1.1	-1.1
Alcohol drinker status: Never	1.1	1.3	1.4	1.2	-1.1
Risk taking	1.1	1.6	3.2	0.2	-1.8
Coronary Artery Disease (CAD)	1.0	1.2	2.0	-1.4	-0.7
Waist Hip Ratio (WHR)	1.0	4.3	8.6	0.1	-2.9
Neuroticism	1.0	2.3	4.6	0.2	2.2
Diabetes (mother)	1.0	1.3	2.1	1.5	0.6
Alcohol usually taken with meals	1.0	1.7	3.2	1.8	0.4
Medication: Paracetamol	1.0	1.7	2.1	1.4	-1.2
Family relationship satisfaction	1.0	1.2	1.7	0.8	1.3
Ever had stillbirth, spontaneous miscarriage or termination	1.0	1.1	1.8	1.4	-0.6
Eye problems/disorders: Glaucoma	1.0	1.2	2.2	1.5	0.3
Prostate Cancer	0.9	1.2	2.0	-0.7	1.4
Primary Biliary Cirrhosis	0.9	1.3	1.9	-0.8	-1.4
Forced expiratory volume in 1-second (FEV1)	0.9	3.0	5.4	-2.3	-0.7
Length of working week for main job	0.9	1.0	1.9	-1.4	-0.4
Medication: Allopurinol	0.9	1.2	1.7	0.9	1.3
Heart disease (mother)	0.9	1.1	1.4	-1.2	0.8
Medication for cholesterol	0.9	1.3	2.6	-0.2	1.6
Medication: Aspirin	0.9	1.2	1.4	-1.0	-1.2
Wears glasses or contact lenses	0.9	1.0	2.0	0.1	1.4
Number of operations (self-reported)	0.9	1.3	2.5	1.6	0.0
Mean Putamen Volume	0.8	0.9	1.8	1.3	-0.4
Systolic blood pressure, automated reading	0.8	2.2	3.4	-1.8	1.0
Medication for hormone replacement therapy	0.8	0.9	1.7	0.1	-1.3
Financial difficulties in last 2 years	0.8	1.0	1.1	1.1	-1.0
Worry too long after embarrassment	0.8	1.3	2.3	1.5	-0.5
Suffer from ‘nerves’	0.8	1.2	1.3	-1.0	1.1
Illness, injury, bereavement, stress in last 2 years	0.8	1.0	1.1	0.9	1.1
Medication: Aspirin	0.8	1.0	1.2	-1.1	-0.9
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.8	1.6	2.5	-0.9	1.6
Medication: Bendroflumethiazide	0.8	1.2	2.1	1.5	-0.5
Ever used hormone-replacement therapy (HRT)	0.7	0.9	1.6	-0.3	-1.3
Medication: Metformin	0.7	1.0	1.0	1.0	-1.0
Fed-up feelings	0.7	1.2	1.9	-0.7	1.4
Forced vital capacity (FVC)	0.7	2.8	5.7	-2.4	-0.0
Happiness	0.7	0.9	1.3	-1.2	0.7
Glaucoma (self-reported)	0.7	0.8	1.4	1.2	-0.4
Smoking status: Previous	0.7	1.0	1.7	1.3	-0.5
Mood swings	0.7	1.2	2.1	-0.6	1.4
Ever had bowel cancer screening	0.7	0.8	1.2	0.6	-1.1
Neuroticism (2016)	0.6	0.9	1.7	1.3	0.3
Hand grip strength (left)	0.6	1.5	1.9	1.0	1.4
Eye problems/disorders: Diabetes related eye disease	0.6	0.6	1.2	1.1	0.0
Number of incorrect matches in round	0.6	1.0	1.1	-1.1	1.0
Medication: Ibuprofen (e.g. Nurofen)	0.6	0.8	1.5	-0.3	-1.2
Peak expiratory flow (PEF)	0.6	1.3	2.7	-1.6	-0.0
Birth weight	0.6	1.3	1.4	1.2	1.1
Alcohol intake frequency.	0.6	1.4	2.0	1.4	-0.9
Systolic Blood Pressure	0.5	2.4	4.2	-2.0	0.7
Relative age of first facial hair	0.5	1.1	2.0	1.4	0.2
Ever had hysterectomy (womb removed)	0.5	0.5	0.5	0.7	-0.7
Impedance of leg (right)	0.5	2.5	4.5	-0.6	2.1
Supplements: Glucosamine	0.5	0.7	1.1	-1.0	-0.6
Impedance of leg (left)	0.5	2.4	3.7	-1.1	1.9
Had menopause	0.5	0.6	0.9	-0.9	-0.6
Depression (self-reported)	0.5	0.6	0.9	0.9	0.5
Lung cancer (father)	0.5	0.6	1.1	-1.0	0.4
Forced expiratory volume in 1-second (FEV1), Best measure	0.5	1.5	2.8	-1.7	-0.4
Pulse wave reflection index	0.5	0.6	1.0	0.5	-1.0
High blood pressure (siblings)	0.5	0.7	0.8	0.8	0.9
Comparative body size at age 10	0.5	1.3	2.0	0.8	-1.4
Mean time to correctly identify matches	0.5	0.9	1.1	-0.9	1.0
Comparative height size at age 10	0.5	2.8	5.1	-2.2	-0.7
Supplements: Vitamin C	0.5	0.6	1.3	-1.1	-0.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.5	0.6	1.2	-0.2	1.1
Smoking status: Current	0.5	0.8	1.0	-1.0	0.8
Heart disease (siblings)	0.5	0.6	1.1	1.1	0.0
Ulcerative Colitis (UC)	0.4	0.8	1.2	0.6	1.1
Sensitivity / hurt feelings	0.4	0.7	1.3	-1.1	-0.4
Pack years adult smoking proportion	0.4	0.6	1.1	-0.3	1.1
Average weekly fortified wine intake	0.4	0.5	0.9	-0.2	1.0
Bilateral oophorectomy (both ovaries removed)	0.4	0.5	0.7	-0.5	-0.9
Sitting height	0.4	3.2	3.8	-1.9	-1.6
Past tobacco smoking	0.4	0.7	0.7	-0.8	0.8
Qualifications: None of the above	0.4	0.8	1.0	1.0	-0.8
Father’s age at death	0.4	0.5	1.1	0.1	1.0
Birth weight of first child	0.4	0.8	1.2	1.1	0.6
Forced vital capacity (FVC), Best measure	0.4	1.5	2.9	-1.7	0.3
Leg fat percentage (right)	0.4	1.6	2.9	0.5	1.7
Leg predicted mass (right)	0.4	1.9	3.6	-0.3	-1.9
Medication: Paracetamol	0.4	0.6	0.6	0.8	-0.8
Ever smoked	0.4	0.7	0.8	0.9	-0.8
Unable to work because of sickness or disability	0.4	0.5	0.9	-0.9	-0.4
Neuroticism (Nagel 2018)	0.3	0.7	1.1	-0.5	1.1
Reaction Time	0.3	0.7	0.8	-0.9	0.7
Height	0.3	5.6	5.7	-2.4	-2.3
Frequency of depressed mood in last 2 weeks	0.3	0.4	0.6	-0.8	0.5
Medication: Co-codamol	0.3	0.3	0.6	0.8	0.2
Diabetes (father)	0.3	0.4	0.7	-0.3	-0.8
Leg fat-free mass (left)	0.3	1.4	2.8	-0.1	-1.7
Leg predicted mass (left)	0.3	1.4	2.8	-0.2	-1.7
Frequency of tenseness / restlessness in last 2 weeks	0.3	0.4	0.7	-0.4	0.8
Mouth/teeth dental problems	0.3	0.4	0.7	-0.9	-0.3
Medication: Ramipril	0.3	0.3	0.6	0.8	0.3
Standing height	0.3	3.1	3.5	-1.6	-1.9
Loud music exposure frequency	0.3	0.3	0.6	-0.8	0.2
Mouth/teeth dental problems: Bleeding gums	0.3	0.4	0.5	-0.6	0.7
Medication: Amlodipine	0.3	0.4	0.5	-0.6	-0.7
Number of full brothers	0.3	0.4	0.8	-0.2	0.9
Age at first live birth	0.3	0.5	0.9	1.0	0.0
Pulse wave peak to peak time	0.3	0.3	0.6	-0.7	-0.3
Qualifications: College or University degree	0.3	1.0	1.5	-0.6	1.2
Eye problems/disorders: None of the above	0.3	0.4	0.4	-0.6	0.7
Medication: Ibuprofen	0.3	0.4	0.6	-0.4	-0.8
Arm predicted mass (right)	0.3	1.3	2.2	-0.7	-1.5
Overall health rating	0.3	0.7	1.3	1.1	-0.3
Illnesses of siblings: Diabetes	0.3	0.4	0.7	0.9	-0.0
Forced expiratory volume in 1-second (FEV1), predicted	0.3	0.5	0.6	-0.8	-0.7
Whole body fat-free mass	0.3	1.5	3.1	-0.1	-1.8
Leg fat-free mass (right)	0.3	1.8	3.5	-0.3	-1.9
Friendships satisfaction	0.3	0.4	0.7	-0.8	0.4
Tinnitus: Yes, now most or all of the time	0.3	0.3	0.4	-0.6	0.5
Pain type(s) experienced in last month: Hip pain	0.3	0.4	0.8	0.9	0.0
Leg fat percentage (left)	0.3	1.2	2.3	0.4	1.5
Vascular/heart problems diagnosed by doctor	0.3	0.7	0.8	0.9	-0.8
Intelligence (Savage-Jansen 2018)	0.2	0.6	0.9	-0.4	1.0
Alzheimer’s Disease (in mother)	0.2	0.3	0.3	0.5	-0.5
Body Mass Index (BMI) (2010)	0.2	0.2	0.3	-0.5	0.4
Smoking Status	0.2	0.5	0.6	0.8	0.5
Cardiovascular Disease	0.2	0.6	1.2	-0.2	-1.1
Lung FVC	0.2	1.1	2.0	-0.4	1.4
Current tobacco smoking	0.2	0.3	0.3	-0.6	0.5
High blood pressure	0.2	0.6	0.7	-0.7	0.9
Stomach or abdominal pain in last month	0.2	0.3	0.6	-0.8	0.1
Fluid intelligence score	0.2	0.4	0.7	0.1	0.9
Arm fat percentage (right)	0.2	0.8	0.9	0.8	1.0
Trunk fat-free mass	0.2	1.4	2.9	-0.0	-1.7
Serious illness, injury or assault of a close relative in last 2 years	0.2	0.2	0.3	-0.4	-0.6
Trunk predicted mass	0.2	1.4	2.8	0.1	-1.7
Breastfed as a baby	0.2	0.2	0.3	0.3	0.6
Qualifications: O levels/GCSEs or equivalent	0.2	0.2	0.4	0.6	0.3
Body fat percentage	0.2	0.6	1.3	-0.1	1.1
Arm fat-free mass (right)	0.2	1.1	1.8	-0.5	-1.4
Health satisfaction	0.2	0.3	0.5	-0.1	0.7
Shortness of breath walking on level ground	0.2	0.3	0.5	-0.2	-0.7
Hypertension (Self-reported)	0.2	0.7	0.8	-0.9	0.7
Illnesses of father: Heart disease	0.2	0.2	0.4	0.6	0.3
Commuting to job workplace: Walk	0.2	0.3	0.5	-0.1	0.7
Back pain experienced in last month	0.2	0.3	0.5	-0.7	-0.1
Breast cancer (self-reported)	0.2	0.2	0.2	0.5	0.4
Whole body water mass	0.2	1.4	2.7	-0.1	-1.6
Basal metabolic rate	0.2	1.1	2.1	-0.0	-1.4
Commuting to job workplace: Cycle	0.2	0.3	0.3	-0.6	0.5
Supplements: Calcium	0.2	0.2	0.3	-0.6	-0.3
Alcohol drinker status: Previous	0.2	0.2	0.3	-0.3	0.5
Pack years of smoking	0.2	0.4	0.7	0.2	0.8
Impedance of whole body	0.2	1.0	1.1	-1.0	1.0
Depressed Affect (Nagel 2018)	0.1	0.2	0.4	-0.1	0.6
Alzheimer’s Disease (including proxy)	0.1	0.1	0.1	0.4	0.3
Verbal and Numeric Reasoning (VNR)	0.1	0.3	0.6	-0.1	0.8
Breast Cancer	0.1	0.2	0.3	-0.4	0.6
Hair Pigment	0.1	3.3	6.5	0.4	2.5
Tanning	0.1	1.4	1.7	1.0	-1.3
Hearing difficulty/problems: Yes	0.1	0.1	0.2	0.4	-0.1
Trunk fat percentage	0.1	0.5	0.8	-0.5	0.9
Hand grip strength (right)	0.1	0.2	0.3	0.5	0.4
Tinnitus: Yes, but not now, but have in the past	0.1	0.1	0.1	0.1	0.4
Serious illness, injury or assault to yourself	0.1	0.1	0.3	-0.2	-0.5
Body mass index (BMI)	0.1	0.3	0.4	0.6	0.4
Waist circumference	0.1	0.5	0.8	0.4	-0.9
Hearing difficulty/problems with background noise	0.1	0.2	0.3	0.1	0.6
Impedance of arm (right)	0.1	0.2	0.5	-0.0	0.7
Time employed in main current job	0.1	0.1	0.2	-0.4	0.2
Alcohol intake versus 10 years previously	0.1	0.1	0.2	-0.4	-0.1
Frequency of tiredness / lethargy in last 2 weeks	0.1	0.2	0.2	0.4	-0.4
Noisy workplace	0.1	0.1	0.1	0.1	0.4
Medication: Lansoprazole	0.1	0.1	0.2	0.2	0.5
Pulse wave Arterial Stiffness index	0.1	0.2	0.2	0.4	0.4
Impedance of arm (left)	0.1	0.5	0.7	-0.8	0.5
Arm fat mass (right)	0.1	0.3	0.5	0.7	0.5
Medication: Blood pressure	0.1	0.2	0.3	-0.0	0.6
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.1	0.1	0.2	-0.5	0.2
Leg fat mass (right)	0.1	0.3	0.6	0.2	0.8
Chest pain or discomfort	0.1	0.2	0.4	0.6	-0.1
Leg pain on walking	0.1	0.1	0.1	0.2	-0.3
Knee pain experienced in last month	0.1	0.1	0.2	-0.2	-0.4
Arm fat percentage (left)	0.1	0.4	0.6	0.3	0.8
Average weekly red wine intake	0.1	0.2	0.3	0.3	0.5
Loneliness, isolation	0.1	0.2	0.2	-0.5	-0.3
Eye problems/disorders: Cataract	0.1	0.2	0.3	0.0	-0.6
Illnesses of father: None of the above (group 1)	0.1	0.2	0.2	0.4	0.4
Guilty feelings	0.1	0.1	0.2	-0.1	0.5
Arm fat-free mass (left)	0.1	0.7	1.5	0.0	-1.2
Ever had prostate specific antigen (PSA) test	0.1	0.1	0.2	0.4	-0.2
Pain experienced in last month	0.1	0.1	0.1	-0.4	0.3
Leg fat mass (left)	0.1	0.3	0.6	0.1	0.8
Arm predicted mass (left)	0.1	0.6	1.3	-0.2	-1.1
Depression (Nagel 2018)	0.0	0.1	0.1	0.3	-0.2
Major Depression (MDD)	0.0	0.0	0.0	0.2	0.0
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0
Ulcerative Colitis	0.0	0.0	0.0	0.2	0.1
BMI	0.0	0.0	0.1	-0.3	0.0
Lung FEV1/FVC ratio	0.0	0.1	0.2	-0.5	-0.2
Severe depression (siblings)	0.0	0.0	0.0	0.2	-0.1
Frequency of unenthusiasm / disinterest in last 2 weeks	0.0	0.0	0.0	-0.2	-0.1
Trunk fat mass	0.0	0.1	0.1	-0.3	0.4
Pain all over the body in last month	0.0	0.0	0.0	-0.2	0.1
Weight	0.0	0.1	0.2	-0.1	-0.4
Hip circumference	0.0	0.2	0.3	-0.1	0.6
Qualifications: A levels/AS levels or equivalent	0.0	0.0	0.0	-0.2	-0.0
Medication for cholesterol, blood pressure or diabetes	0.0	0.1	0.1	0.3	0.2
Whole body fat mass	0.0	0.1	0.2	-0.1	0.5
Handedness (chirality/laterality): Left-handed	0.0	0.0	0.0	-0.2	-0.0
Arm fat mass (left)	0.0	0.2	0.3	0.6	0.3
Financial situation satisfaction	0.0	0.0	0.1	0.3	0.1
Medication: Blood pressure	0.0	0.0	0.1	0.1	0.3
Medication: Atorvastatin	0.0	0.1	0.1	0.3	0.1

Hub : Genes

PPP1R32

Models

Trait associations