TWAS hub - PPP2R5A

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0900	0.0270	2.7e-05	0.052	0.052	0.056	0.053	0.053	5.5e-07	6.4e-07	1.9e-07	4.8e-07	4.6e-07
2	GTEx	Lung	0.1036	0.0398	1.6e-03	0.034	NA	0.004	NA	0.006	1.3e-03	NA	1.5e-01	NA	9.9e-02
3	GTEx	Thyroid	0.2420	0.0520	1.9e-10	0.185	NA	0.206	NA	0.207	3.9e-14	NA	1.1e-15	NA	9.6e-16
4	GTEx	Whole Blood	0.1930	0.0430	1.7e-09	0.201	NA	0.177	NA	0.189	2.8e-18	NA	4.6e-16	NA	3.2e-17
5	METSIM	Adipose	0.0487	0.0171	3.4e-04	0.023	0.031	0.016	0.030	0.018	1.9e-04	1.8e-05	1.8e-03	2.1e-05	9.4e-04
6	NTR	Blood	0.0541	0.0135	1.7e-12	0.058	0.040	0.055	0.049	0.062	3.5e-18	8.1e-13	3.7e-17	1.7e-15	2.2e-19
7	YFS	Blood	0.3164	0.0309	0.0e+00	0.506	0.491	0.515	0.390	0.515	9.9e-196	3.5e-187	1.8e-200	7.8e-138	1.5e-200
8	TCGA	Prostate Adenocarcinoma	0.0477	0.0246	1.8e-03	0.033	0.032	0.039	NA	0.043	2.1e-04	2.4e-04	5.7e-05	NA	2.5e-05
9	TCGA	Testicular Germ Cell Tumors	0.2100	0.0960	8.4e-05	0.177	0.146	0.073	NA	0.155	7.4e-07	7.5e-06	1.5e-03	NA	4.1e-06

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Smoking status: Previous	5.4	8.1	12.6	0.1	-3.3	-2.8	-3.4	-2.4	-3.5	-3.5	-3.0	-1.7
Past tobacco smoking	5.1	9.4	14.4	-0.5	3.3	2.9	3.8	2.7	3.8	3.8	3.2	2.1
Length of working week for main job	5.1	5.6	8.9	-0.8	3.0	2.1	2.7	2.5	2.4	2.7	2.4	2.1
Ever smoked	5.1	8.9	13.6	1.0	-3.3	-2.9	-3.7	-2.8	-3.4	-3.4	-3.2	-2.2
Medication: Amlodipine	4.7	6.7	9.6	-0.5	-3.0	-2.7	-3.1	-2.8	-3.1	-3.1	-2.6	-0.7
Commuting to job workplace: Public transport	4.5	5.4	9.4	2.2	-2.1	-1.5	-2.6	-3.0	-2.0	-2.3	-3.1	-1.7
Myopia	4.1	5.9	11.4	0.3	-1.9	-1.8	-3.0	-3.4	-2.9	-2.9	-2.3	-2.0
Mouth/teeth dental problems: Mouth ulcers	4.0	6.4	15.0	0.2	-2.8	-3.9	-2.8	-2.3	-2.4	-2.6	-2.2	-1.8
Smoking Status	3.8	9.1	15.0	0.6	-3.3	-2.9	-3.8	-1.7	-3.9	-3.7	-2.7	-3.0
Financial situation satisfaction	3.6	4.5	8.5	-0.2	2.9	2.3	2.6	1.3	2.4	2.5	1.9	1.6
Family relationship satisfaction	3.1	3.8	6.4	-0.5	2.1	2.0	2.5	1.5	2.2	2.4	2.2	0.9
Waist Hip Ratio (WHR)	3.0	13.4	38.2	6.2	-2.4	-1.1	-2.9	-5.5	-0.5	-1.9	-5.6	-1.3
Unable to work because of sickness or disability	3.0	3.9	6.0	-1.2	1.8	2.5	2.3	1.5	1.8	1.9	2.2	2.2
Pulse rate	2.8	4.7	8.4	0.3	2.5	2.9	2.6	1.5	2.6	2.7	1.6	1.2
Exposure to tobacco smoke at home	2.8	3.2	10.2	1.5	-1.1	-1.9	-1.8	-3.2	-1.0	-1.5	-2.2	-0.6
Crohns Disease (2012)	2.7	4.3	8.8	-0.0	2.1	1.6	2.7	0.9	2.7	2.8	3.0	0.2
Hand grip strength (left)	2.7	7.0	10.3	0.6	-3.0	-2.7	-3.0	-2.2	-2.9	-3.2	-2.2	-3.0
Hayfever, allergic rhinitis or eczema	2.7	5.8	11.2	0.5	-2.6	-2.0	-3.2	-1.1	-3.4	-3.1	-2.2	-2.1
Bilateral oophorectomy (both ovaries removed)	2.6	3.0	7.6	1.8	-1.8	-2.7	-1.5	-1.7	-0.8	-1.4	-1.7	-1.5
Medication: Aspirin	2.6	3.4	5.1	0.6	-2.1	-1.9	-2.3	-1.4	-2.2	-2.2	-1.6	-1.6
Illnesses of father: None of the above (group 1)	2.5	3.1	7.9	1.0	-1.7	-2.8	-1.9	-1.6	-1.1	-1.5	-2.3	-1.0
Birth weight of first child	2.4	4.3	8.9	0.6	-2.0	-2.5	-2.5	-1.5	-2.2	-2.4	-3.0	0.1
Medication: Aspirin	2.4	3.2	4.8	0.7	-1.9	-1.8	-2.2	-1.6	-2.2	-2.1	-1.6	-1.4
Schizophrenia vs Biploar Disorder	2.3	3.0	7.3	0.5	-1.9	-1.1	-1.9	-2.7	-1.8	-1.8	-2.0	-0.8
Hearing aid user	2.3	2.6	6.7	-0.1	2.1	1.8	1.8	0.5	1.7	1.6	0.4	2.6
Medication: Bendroflumethiazide	2.3	3.4	7.8	-0.9	-2.8	-1.7	-1.7	-2.4	-1.9	-2.1	-1.7	0.1
Allergy or Eczema	2.2	5.8	11.8	0.5	-2.5	-2.2	-3.1	-0.8	-3.4	-3.1	-2.0	-2.3
Health satisfaction	2.2	2.8	5.0	0.1	2.2	0.9	2.0	1.7	2.0	1.9	2.2	0.3
Pain type(s) experienced in last month: Hip pain	2.2	2.8	4.5	-1.9	1.6	1.5	2.0	1.4	1.4	1.7	2.1	1.3
Schizophrenia (2018)	2.0	4.2	7.5	-0.3	-2.7	-1.7	-2.5	-1.1	-2.7	-2.7	-2.1	-1.0
HbA1C	2.0	2.2	5.4	1.4	-1.4	-1.1	-1.5	-2.3	-1.1	-1.4	-1.2	-1.7
Primary Biliary Cirrhosis	2.0	2.8	7.7	0.7	-1.1	-2.8	-1.9	-0.8	-1.6	-1.8	-0.7	-2.2
Lung cancer (father)	2.0	2.3	4.9	-1.2	1.4	1.5	1.8	0.3	1.4	1.5	1.5	2.2
Qualifications: nursing, teaching	2.0	3.0	9.7	3.1	-0.1	-0.8	-1.0	-2.4	0.1	-0.5	-3.1	0.6
Relative age voice broke	1.9	2.9	4.5	1.3	-1.6	-2.0	-2.1	-1.5	-1.4	-1.8	-1.9	-1.5
Glaucoma (self-reported)	1.9	2.3	11.2	-3.4	0.5	0.3	0.7	1.6	-0.1	0.4	1.9	1.5
Number of full sisters	1.9	2.3	6.2	-0.2	1.6	2.5	1.6	1.2	1.4	1.6	1.6	0.8
Supplements: Vitamin C	1.9	2.3	5.0	0.8	1.8	1.1	1.7	1.1	2.2	2.0	1.1	0.8
Hypertension (Self-reported)	1.9	5.4	8.8	-0.1	-2.8	-2.3	-2.5	-3.0	-2.5	-2.6	-1.9	-1.7
Guilty feelings	1.9	2.9	5.5	-0.9	-2.3	-1.8	-1.7	-1.4	-2.1	-2.0	-1.6	0.1
Mean Putamen Volume	1.8	2.1	4.5	0.3	1.3	1.5	2.0	0.0	2.1	1.8	1.6	0.6
Hair/balding pattern: Pattern 2	1.8	2.3	6.9	-0.6	1.3	1.2	1.7	1.4	1.5	1.6	2.6	-0.8
Allergy	1.8	4.1	10.7	0.9	2.2	1.5	2.7	-0.4	3.3	2.8	0.8	1.7
Medication: Simvastatin	1.7	2.5	5.0	-0.6	-1.9	-1.1	-1.9	-1.0	-2.2	-2.0	-1.8	0.1
Average weekly champagne plus white wine intake	1.7	2.4	5.5	-0.2	1.7	1.0	1.9	0.7	1.7	2.0	1.2	2.4
Cardiovascular Disease	1.6	5.2	8.5	-0.6	-2.9	-2.2	-2.7	-2.2	-2.9	-2.8	-2.1	-1.2
Impedance of arm (right)	1.6	7.5	31.7	5.6	0.4	-0.3	-0.5	-4.6	1.8	0.5	-3.2	-0.3
Qualifications: A levels/AS levels or equivalent	1.6	3.6	11.8	3.4	-0.2	-1.7	-1.4	-2.3	-0.1	-0.8	-2.9	-0.8
Pulse rate, automated reading	1.6	5.2	10.6	1.8	2.7	3.3	2.5	-0.2	3.1	2.7	0.5	1.6
Basal cell carcinoma (self-reported)	1.6	2.0	3.4	-0.6	-1.6	-1.7	-1.9	-1.0	-1.7	-1.6	-1.4	-0.0
Schizophrenia (2014)	1.5	3.3	6.3	-0.1	-2.5	-1.8	-2.1	-1.2	-2.2	-2.3	-1.9	-1.0
Qualifications: None of the above	1.5	3.1	15.6	-4.0	-0.6	1.0	1.0	1.3	-0.6	0.1	2.8	0.0
Breastfed as a baby	1.5	1.9	5.0	0.5	-1.7	-0.7	-1.5	-2.2	-1.1	-1.4	-1.7	-0.7
Qualifications: O levels/GCSEs or equivalent	1.5	2.4	7.0	2.1	-0.4	-2.0	-1.3	-1.9	-0.1	-0.8	-2.6	0.5
Alzheimer’s Disease (including proxy)	1.4	2.0	6.2	-2.4	0.7	0.6	1.3	1.6	0.2	0.8	2.5	0.2
Diabetes (mother)	1.4	1.8	4.6	1.7	1.4	1.0	1.5	-0.8	2.1	1.8	0.4	-0.0
High blood pressure	1.4	4.0	6.7	-0.2	-2.4	-2.0	-2.1	-2.6	-2.2	-2.2	-1.5	-1.6
Frequency of tiredness / lethargy in last 2 weeks	1.4	2.3	6.5	1.7	1.5	1.2	1.8	-0.7	2.5	1.9	0.4	0.7
Impedance of arm (left)	1.4	6.3	27.2	5.2	0.7	-0.1	-0.0	-4.0	2.4	1.0	-2.6	0.1
Medication: Allopurinol	1.4	1.8	3.5	-1.8	-1.8	-1.9	-1.1	-1.0	-1.4	-1.3	-0.9	0.1
Medication: Seretide 50 evohaler	1.4	1.6	5.2	-0.6	-1.2	-1.3	-1.1	-0.0	-1.6	-1.2	0.5	-2.3
Alzheimer’s Disease (in father)	1.3	1.4	4.3	-2.1	0.9	-0.0	0.6	1.5	-0.0	0.4	1.0	1.9
Lupus	1.3	1.9	4.7	0.2	1.6	2.2	1.6	0.8	1.6	1.6	1.1	0.7
Impedance of leg (right)	1.3	6.4	21.2	4.4	-1.1	-1.1	-1.4	-4.6	0.4	-0.8	-1.8	-3.0
Fed-up feelings	1.3	2.4	5.6	-1.0	1.9	1.1	1.9	1.1	1.3	1.7	2.4	0.7
Age when periods started (menarche)	1.3	3.0	13.3	3.6	0.1	-0.7	-0.8	-2.4	0.6	-0.2	-1.1	-2.4
Chronic bronchitis/emphysema (father)	1.3	1.5	3.2	-0.5	1.1	0.1	1.5	1.8	1.4	1.4	1.5	0.6
Pain all over the body in last month	1.3	1.4	2.6	-0.7	1.5	1.4	1.1	1.3	0.9	1.0	1.6	0.4
Medication: Lansoprazole	1.3	1.5	4.8	1.2	-0.9	-1.2	-1.2	-1.3	-0.7	-0.9	-0.7	-2.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.3	1.6	3.8	1.4	0.7	1.9	1.0	0.3	1.0	1.0	1.1	-1.8
High cholesterol (Self-reported)	1.3	2.4	5.1	-0.7	-2.3	-1.3	-1.8	-1.0	-2.0	-1.9	-1.4	-0.3
Impedance of whole body	1.3	6.4	27.7	5.3	-0.0	-0.6	-0.5	-4.3	1.8	0.3	-2.2	-1.6
Tanning	1.2	14.9	32.3	5.7	-2.9	-1.9	-3.8	-5.2	-1.9	-3.1	-5.1	-3.1
Relative age of first facial hair	1.2	2.5	8.3	1.0	-1.9	-2.0	-1.4	-0.6	-1.0	-1.4	-0.3	-2.9
Pack years adult smoking proportion	1.2	1.8	3.6	-0.3	0.7	0.9	1.9	0.9	1.9	1.8	1.2	1.6
Impedance of leg (left)	1.2	5.9	18.4	4.3	-0.9	-1.0	-1.3	-4.0	0.3	-0.8	-1.6	-3.4
Mouth/teeth dental problems: Dentures	1.2	2.1	6.7	-2.6	0.7	0.8	1.4	1.5	0.5	1.2	1.9	1.3
Blood clot in the leg (DVT)	1.2	1.5	2.8	-0.8	1.7	1.2	1.2	1.7	0.8	1.0	1.4	0.8
Medication for cholesterol, blood pressure or diabetes	1.2	2.0	4.1	1.4	2.0	-0.0	1.2	2.0	1.6	1.5	1.3	-0.4
Back pain experienced in last month	1.2	1.7	4.7	1.7	-0.5	-1.0	-1.1	-2.0	-0.3	-0.8	-2.2	0.4
Irritability	1.2	2.0	3.9	0.6	1.1	1.2	1.7	1.3	2.0	1.9	1.7	-0.2
Alzheimer’s Disease (in mother)	1.1	1.2	4.1	-1.6	0.5	1.1	0.9	1.3	-0.0	0.5	2.0	-0.6
Crohns Disease (2017)	1.1	2.4	5.2	0.6	1.9	1.2	1.9	-0.1	2.3	2.1	1.7	0.5
Alcohol usually taken with meals	1.1	1.7	4.0	1.9	1.6	0.8	1.0	0.9	2.0	1.6	0.2	0.6
Age at first live birth	1.1	1.9	7.2	1.7	-1.6	-0.7	-1.2	-0.5	-0.6	-1.1	-0.9	-2.7
Commuting to job workplace: Car/motor vehicle	1.1	1.3	3.7	-1.2	0.8	0.1	1.2	1.9	0.8	0.9	1.6	0.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.1	1.3	3.2	-1.3	0.4	1.0	1.2	1.8	0.5	0.7	1.4	1.0
Medication: Gliclazide	1.1	1.3	3.3	-1.3	0.8	0.5	1.3	0.7	1.3	1.3	0.6	1.8
Eye problems/disorders: Glaucoma	1.1	1.3	6.1	-2.5	0.4	0.1	0.5	1.2	-0.0	0.4	1.2	1.4
Vascular/heart problems diagnosed by doctor	1.1	3.0	5.0	-0.2	2.1	1.7	1.9	2.2	1.9	1.9	1.5	1.6
LDL Cholesterol	1.0	1.6	2.9	-1.2	-1.7	-1.1	-1.4	-1.0	-1.6	-1.6	-0.5	-0.3
Neuroticism (2016)	1.0	1.4	3.3	-0.8	0.4	1.0	1.4	1.7	1.0	1.2	1.8	0.4
Heel T-Score	1.0	7.8	12.7	-0.7	-3.5	-3.4	-3.5	-1.3	-3.5	-3.6	-2.1	-1.6
Height	1.0	18.3	59.6	7.7	-0.9	-2.5	-2.8	-5.8	0.2	-1.5	-7.4	0.5
Respiratory disease	1.0	2.1	5.0	0.2	-1.7	-0.3	-1.9	0.3	-2.2	-2.0	-0.8	-1.7
Diabetes (father)	1.0	1.3	6.3	1.1	-0.3	1.0	-0.6	-2.5	-0.2	-0.6	-1.4	-0.1
Qualifications: CSEs or equivalent	1.0	1.3	6.6	-2.6	0.3	1.1	0.8	0.7	-0.2	0.3	1.6	0.5
Sitting height	1.0	7.3	28.5	5.3	-1.0	-2.5	-1.6	-2.8	0.5	-0.8	-4.2	-0.7
Nervous feelings	1.0	1.8	5.7	-2.4	0.8	1.1	1.2	1.1	0.5	1.1	1.5	1.6
Had other major operations	1.0	1.2	2.4	0.7	1.5	1.5	1.1	0.5	1.3	1.3	0.5	0.9
Father’s age at death	1.0	1.3	2.8	-0.2	-1.7	-1.0	-1.4	-0.9	-1.4	-1.4	-0.9	-0.7
Gout (self-reported)	1.0	1.4	2.6	-1.6	-1.5	-1.2	-1.1	-0.3	-1.5	-1.3	-0.3	-0.8
Eye problems/disorders: None of the above	1.0	1.1	5.2	0.3	-0.9	-0.3	-0.2	-1.6	-0.6	-0.4	0.8	-2.3
Medication: Blood pressure	1.0	1.8	3.6	-1.3	-1.8	-0.5	-1.3	-1.9	-1.5	-1.4	-1.3	0.3
Medication for cholesterol	1.0	1.6	2.7	-1.6	0.9	1.6	1.4	1.3	0.9	1.1	1.3	1.1
Smoking status: Current	1.0	1.6	4.3	1.0	-0.9	-1.3	-1.5	-0.3	-1.4	-1.3	-0.8	-2.1
Mother’s age at death	1.0	1.3	3.1	1.5	-0.6	-1.5	-0.9	-1.8	-0.5	-0.7	-0.6	-1.4
Medication: Paracetamol	1.0	1.6	3.1	-0.9	1.5	1.1	1.1	1.8	0.9	1.1	1.6	1.0
Pack years of smoking	1.0	1.5	3.3	-0.0	0.6	0.8	1.8	0.8	1.8	1.7	1.0	1.5
Ovarian Cancer	0.9	1.1	5.0	-2.2	0.4	-0.0	-0.3	1.3	-1.1	-0.6	0.7	1.0
Current tobacco smoking	0.9	1.5	3.8	0.7	-1.0	-1.4	-1.4	-0.2	-1.4	-1.3	-0.7	-1.9
Heel bone mineral density (BMD) T-score, automated (left)	0.9	2.0	4.8	1.6	-0.8	-0.6	-1.4	-2.2	-0.9	-1.3	-1.4	-1.8
Stomach or abdominal pain in last month	0.9	1.1	2.5	1.1	1.1	0.6	1.0	-0.5	1.6	1.2	0.9	-1.0
Had menopause	0.9	1.1	4.0	-1.1	0.7	0.9	1.2	0.4	0.7	1.1	2.0	-0.2
Medication: Ventolin 100micrograms inhaler	0.9	1.2	3.1	-0.1	-1.0	-0.6	-1.4	0.4	-1.8	-1.5	-0.6	-1.1
Reason for reducing amount of alcohol drunk: Health precaution	0.9	1.0	2.6	-1.1	-1.6	-1.5	-0.8	0.1	-1.1	-1.0	-0.0	-0.3
Handedness (chirality/laterality): Left-handed	0.9	1.1	1.8	0.8	-0.8	-0.8	-1.4	-1.0	-1.3	-1.2	-1.1	-0.8
Commuting to job workplace: Walk	0.9	1.0	4.5	2.1	0.6	0.5	-0.2	-1.0	0.6	0.3	-0.7	-1.2
Eye problems/disorders: Cataract	0.9	1.1	2.6	-0.6	0.8	0.6	0.9	1.6	1.0	1.1	0.7	1.6
Deep venous thrombosis (DVT) (self-reported)	0.9	1.2	2.4	-0.6	1.5	1.1	1.1	1.2	0.7	0.9	1.5	0.5
Bipolar Disorder or Schizophrenia	0.8	2.0	3.7	-0.5	-1.6	-1.5	-1.7	-0.2	-1.9	-1.9	-1.4	-0.4
Intelligence (Savage-Jansen 2018)	0.8	2.4	11.0	3.3	0.5	-0.5	-0.3	-2.2	1.4	0.5	-1.8	0.3
HDL Cholesterol	0.8	1.4	8.7	-3.0	-0.2	-0.1	0.0	0.8	-1.1	-0.4	1.2	0.6
Type 2 Diabetes (T2D) (2012)	0.8	0.9	3.6	1.9	0.0	0.4	-0.3	-1.3	0.4	0.0	-1.5	0.4
Diverticular disease/diverticulitis (self-reported)	0.8	1.0	2.0	-0.0	0.8	1.1	1.2	1.1	1.0	1.0	1.4	0.1
Asthma	0.8	1.5	4.5	-1.1	-1.2	-0.4	-1.6	0.8	-2.1	-1.7	-0.3	-0.5
Depression (self-reported)	0.8	1.0	2.5	-0.2	-1.6	-0.8	-1.0	-0.9	-1.2	-1.2	-0.7	-0.8
Pulse wave Arterial Stiffness index	0.8	0.9	4.7	1.1	0.3	2.2	0.6	-0.5	0.9	0.5	-0.6	0.3
Hair/balding pattern: Pattern 4	0.8	1.9	6.7	-1.1	1.1	1.6	1.5	0.3	1.2	1.3	0.5	2.6
Worry too long after embarrassment	0.8	1.4	3.1	1.8	-0.9	-0.6	-1.0	-1.6	-0.6	-0.7	-1.6	-0.9
Pulse wave peak to peak time	0.8	0.9	5.4	-0.7	-0.3	-2.3	-0.7	0.3	-0.8	-0.6	0.4	-0.5
Overall health rating	0.8	1.8	3.9	0.1	2.0	1.1	1.5	1.2	1.4	1.4	1.8	0.5
Age at last live birth	0.8	1.2	6.7	1.3	-0.6	1.0	0.0	0.7	0.2	0.1	0.6	-2.6
Average weekly red wine intake	0.8	1.1	2.2	1.5	-0.6	-0.9	-1.3	-0.9	-0.7	-0.9	-1.4	-1.0
Breast cancer (self-reported)	0.8	0.9	3.4	-1.8	0.4	0.6	0.5	1.3	0.0	0.4	0.5	1.4
Asthma (self-reported)	0.8	1.6	4.2	-0.7	-1.4	-0.5	-1.7	0.7	-2.0	-1.7	-0.4	-0.8
Number of self-reported non-cancer illnesses	0.8	1.4	3.3	0.0	-1.3	-0.6	-1.5	-0.8	-1.8	-1.7	-1.0	-0.6
Wears glasses or contact lenses	0.8	0.9	3.7	-1.9	-0.8	-0.8	-0.5	-0.3	-1.4	-1.0	0.2	0.4
Ever taken oral contraceptive pill	0.8	0.8	4.9	-0.6	0.6	0.8	0.6	0.3	0.7	0.6	-0.0	2.2
Depression (Nagel 2018)	0.7	1.1	2.9	0.3	-1.3	-0.2	-1.0	-1.7	-0.9	-1.0	-1.3	-0.5
Verbal and Numeric Reasoning (VNR)	0.7	1.6	4.4	2.1	-0.0	-0.7	-1.0	-1.9	0.2	-0.4	-2.0	0.5
Prostate Cancer	0.7	0.9	3.6	1.6	0.3	0.7	-0.1	-1.9	0.5	-0.0	-0.9	-0.7
Ulcerative Colitis	0.7	1.1	2.8	-1.7	0.2	1.2	0.8	1.0	0.4	0.7	1.1	1.4
Eye problems/disorders: Diabetes related eye disease	0.7	0.8	3.6	1.3	-0.0	-0.6	-0.7	-0.7	0.1	-0.3	-1.9	0.8
Hand grip strength (right)	0.7	1.8	4.8	-0.2	-1.6	-1.8	-1.2	-0.3	-1.4	-1.6	-0.4	-2.2
Supplements: Glucosamine	0.7	0.9	3.6	-0.9	0.7	1.3	0.5	1.9	0.1	0.5	0.8	0.6
Medication: Ramipril	0.7	0.9	2.0	-1.4	-1.3	-0.9	-0.6	-1.1	-0.9	-0.8	-0.5	0.8
Hair/balding pattern: Pattern 3	0.7	1.0	2.3	-0.2	-0.7	-0.8	-1.3	-0.4	-1.4	-1.2	-1.5	0.4
Chronic bronchitis/emphysema (mother)	0.7	0.8	1.7	0.7	0.8	0.5	1.2	0.5	1.3	1.1	0.7	0.6
Comparative body size at age 10	0.7	2.0	8.2	-2.9	-0.4	1.2	1.0	0.6	-0.0	0.4	1.0	2.4
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.7	0.9	2.8	-0.8	-0.7	-1.1	-0.5	-0.7	-1.1	-0.9	0.2	-1.7
Illness, injury, bereavement, stress in last 2 years	0.7	0.9	2.2	-0.3	-1.5	-0.9	-0.8	-1.5	-0.6	-0.8	-0.6	-0.6
Miserableness	0.7	1.1	2.4	-1.3	1.5	1.6	1.0	0.4	0.5	1.0	1.1	0.7
Breast Cancer	0.6	1.4	3.3	1.3	1.2	1.8	0.9	0.5	1.1	1.2	1.0	-1.0
Age at First Birth	0.6	0.8	3.3	0.5	-1.2	-1.0	-0.8	-0.4	-0.6	-0.6	-0.2	-1.8
BMI	0.6	3.3	7.5	-2.4	1.1	1.8	1.7	2.7	0.6	1.2	1.7	2.1
Hearing difficulty/problems: Yes	0.6	0.9	3.0	0.6	1.7	1.0	0.9	-0.4	1.2	1.1	0.4	0.5
Townsend deprivation index at recruitment	0.6	0.8	2.6	-0.2	0.6	1.4	0.7	0.5	0.4	0.4	1.6	-1.1
Body mass index (BMI)	0.6	2.5	9.1	-2.1	1.0	1.0	1.2	3.0	0.2	0.7	1.5	1.7
Medication: Cholesterol lowering	0.6	0.9	1.8	-1.2	-1.2	0.1	-0.8	-1.3	-1.2	-1.0	-0.8	0.4
Standing height	0.6	5.7	29.9	5.5	0.2	-0.7	-0.9	-1.7	1.1	-0.1	-4.0	0.2
Wheeze or whistling in the chest in last year	0.6	1.1	4.0	-2.0	-0.2	0.4	-0.0	1.9	-0.8	-0.3	0.9	0.7
Neck or shoulder pain in last month	0.6	0.9	2.8	-0.2	-0.9	-0.7	-0.6	-1.7	-0.8	-0.9	-0.2	-1.3
Suffer from ‘nerves’	0.6	1.0	1.8	0.9	-0.6	-1.3	-1.3	-0.7	-1.0	-1.0	-1.3	-0.5
Ever had stillbirth, spontaneous miscarriage or termination	0.6	0.7	3.0	-0.1	-0.3	0.5	0.1	1.0	-0.1	-0.1	1.4	-1.7
Medication: Blood pressure	0.6	1.1	1.9	0.4	-0.8	-1.4	-1.2	-0.6	-1.3	-1.2	-0.7	-1.1
Supplements: Fish oil (including cod liver oil)	0.6	0.7	1.9	-1.3	0.7	0.6	0.6	1.2	0.0	0.5	1.4	0.1
Illnesses of father: High blood pressure	0.6	0.7	2.4	-0.9	0.8	1.3	0.2	1.5	-0.3	0.2	0.9	0.3
Fractured/broken bones in last 5 years	0.6	0.7	2.1	-0.6	-0.8	-0.7	-0.9	0.2	-1.5	-1.1	-0.1	-1.0
Blood Red Count	0.5	4.4	21.4	4.6	1.9	1.3	0.6	-1.3	2.3	1.4	-1.9	0.2
Lung FEV1/FVC ratio	0.5	2.5	4.1	-1.7	-1.6	-1.2	-1.6	-0.3	-1.7	-1.7	-2.0	1.8
Leg fat-free mass (left)	0.5	2.5	7.6	-0.1	1.4	1.1	1.2	2.8	1.1	1.2	-0.2	2.7
Multivitamins +/- minerals	0.5	0.6	3.5	1.9	1.0	0.1	-0.2	-0.3	0.4	0.4	-0.6	-0.0
Leg predicted mass (left)	0.5	2.4	7.6	-0.1	1.4	1.1	1.2	2.8	1.0	1.2	-0.2	2.7
Mouth/teeth dental problems	0.5	0.7	2.1	0.8	1.2	1.5	0.7	0.8	0.8	0.7	0.6	0.1
Fluid intelligence score	0.5	1.1	3.3	0.8	-0.8	-0.9	-1.1	-1.5	-0.7	-0.9	-1.8	0.2
Happiness	0.5	0.6	2.4	-1.0	0.4	0.3	0.6	1.0	-0.1	0.4	1.6	0.0
Prospective memory result	0.5	0.6	2.3	-1.3	-0.1	0.4	-0.1	-0.8	-0.7	-0.5	-0.4	1.5
Ever highly irritable/argumentative for 2 days	0.5	0.6	1.8	0.3	-1.0	-1.3	-0.7	-0.4	-0.4	-0.7	-0.9	0.3
Exposure to tobacco smoke outside home	0.5	0.7	1.6	0.9	1.3	0.9	0.8	0.7	0.9	0.9	0.4	0.1
Qualifications: College or University degree	0.5	1.6	8.4	2.9	1.2	-0.4	0.4	-0.6	1.3	1.0	-0.9	-0.1
Mouth/teeth dental problems: Loose teeth	0.5	0.5	1.6	-0.3	-0.7	0.1	-0.8	0.0	-1.2	-0.8	-0.0	-1.2
Emphysema/chronic bronchitis	0.5	0.5	3.0	0.4	-0.3	0.4	-0.3	0.6	-0.5	-0.4	0.4	-1.7
Medication: Omeprazole	0.5	0.6	1.1	0.7	1.1	1.0	0.7	-0.3	1.0	0.8	0.2	0.3
Qualifications: NVQ or HND or HNC or equivalent	0.5	0.7	1.5	-0.1	-0.9	-0.6	-1.1	-0.3	-0.9	-1.1	-1.2	-0.0
Leg fat-free mass (right)	0.5	2.6	9.4	-0.2	1.4	1.1	1.2	3.1	0.9	1.2	-0.2	2.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.5	1.0	4.2	-2.0	-1.1	-0.9	-0.3	1.2	-0.9	-0.6	0.4	0.1
Leg predicted mass (right)	0.5	2.9	10.0	-0.3	1.6	1.2	1.4	3.2	1.1	1.3	-0.0	2.7
Medication: Atorvastatin	0.5	0.6	1.0	-1.0	0.7	0.9	0.9	-0.1	0.7	0.7	0.7	0.8
Alcohol drinker status: Never	0.5	0.6	2.1	1.2	0.4	-0.1	0.2	-1.4	0.9	0.5	-0.4	0.3
Worry (Nagel 2018)	0.4	0.8	1.8	-1.0	-1.4	-1.0	-0.9	0.2	-1.3	-1.0	-0.2	-0.5
Major Depression (MDD)	0.4	0.5	1.4	-1.2	-0.8	-0.3	0.0	1.1	-0.6	-0.2	0.9	-0.6
Bipolar Disorder (2011)	0.4	0.4	1.2	-0.7	0.7	0.2	0.3	1.1	0.1	0.2	-0.2	1.0
Body Mass Index (BMI) (2010)	0.4	0.6	1.3	-0.1	-1.1	-0.4	-1.1	-0.4	-1.1	-0.8	-0.6	-0.4
Blood Eosinophil Count	0.4	2.8	5.5	-0.4	-2.4	-1.9	-2.1	0.2	-2.1	-2.0	-1.7	-0.6
Blood White Count	0.4	3.0	5.0	0.7	2.0	1.7	2.2	1.7	2.2	2.0	1.7	0.1
Lung FVC	0.4	2.0	6.2	-1.1	0.1	-1.2	1.0	2.2	0.4	0.6	2.5	-1.7
Chronotype (morning person)	0.4	0.9	3.2	-1.8	0.6	1.2	0.7	1.1	0.0	0.6	0.8	0.8
Sensitivity / hurt feelings	0.4	0.8	1.6	-1.1	-1.2	-0.7	-0.9	-0.4	-1.3	-1.0	-0.5	0.2
Ever used hormone-replacement therapy (HRT)	0.4	0.5	2.4	-0.3	0.6	0.2	-0.0	-1.5	0.0	0.1	-0.1	1.1
Ever had hysterectomy (womb removed)	0.4	0.4	2.0	-0.2	0.3	-0.7	0.3	-0.8	0.6	0.4	-0.3	1.4
Medication: Metformin	0.4	0.5	1.5	-0.7	-0.4	-0.5	-0.6	-0.6	-0.5	-0.7	-1.0	1.2
Average weekly fortified wine intake	0.4	0.5	3.0	1.7	0.5	0.3	0.1	0.2	0.8	0.3	-0.7	-0.0
Number of incorrect matches in round	0.4	0.7	2.4	-0.6	0.6	0.6	0.6	1.1	0.1	0.4	1.5	-0.8
Heel bone mineral density (BMD) T-score, automated (right)	0.4	0.9	4.0	0.6	-0.6	-0.7	-1.1	-0.0	-0.9	-1.0	-0.1	-2.0
Hip circumference	0.4	1.9	10.0	-0.8	1.0	0.8	0.9	3.2	0.4	0.7	0.6	1.6
Time employed in main current job	0.4	0.5	1.4	-0.1	-1.2	-0.7	-0.6	-0.2	-0.5	-0.6	-1.0	0.8
Falls in the last year	0.4	0.5	1.1	-1.0	-0.5	-0.3	-0.5	0.7	-0.9	-0.8	0.7	-0.8
Serious illness, injury or assault of a close relative in last 2 years	0.4	0.4	1.2	0.7	-0.1	-0.2	-0.8	-0.3	-0.5	-0.6	-1.1	0.9
Loud music exposure frequency	0.4	0.5	1.5	-1.1	0.1	-0.5	-0.2	1.2	-0.8	-0.4	0.7	-0.2
Medication: Paracetamol	0.4	0.7	1.6	-0.3	1.1	0.7	0.7	1.3	0.6	0.8	1.0	0.6
Shortness of breath walking on level ground	0.4	0.4	0.9	-0.8	-0.9	-0.5	-0.6	0.1	-0.9	-0.7	-0.4	-0.4
Medication: Ibuprofen	0.4	0.4	1.5	-0.7	0.5	0.2	0.5	1.2	0.3	0.4	0.5	0.9
Alcohol intake frequency.	0.4	0.9	1.9	0.1	1.2	1.4	1.0	0.7	1.1	1.1	1.2	-0.3
Leg pain on walking	0.4	0.5	2.4	-0.6	-0.1	-0.3	-0.0	0.9	-0.6	-0.4	0.7	-1.6
Mood swings	0.4	0.7	1.6	-0.1	0.9	0.9	0.8	1.3	0.4	0.6	1.2	-0.5
Friendships satisfaction	0.4	0.5	0.9	-0.2	0.4	0.4	0.9	0.9	0.8	0.8	1.0	-0.1
Ever had prostate specific antigen (PSA) test	0.4	0.5	1.2	-0.4	-0.8	0.2	-0.6	-0.1	-0.9	-0.9	-1.1	0.3
Depressed Affect (Nagel 2018)	0.3	0.7	1.4	-1.0	1.0	0.9	1.0	0.9	0.3	0.6	1.2	0.1
Irritable Bowel Disease (IBD)	0.3	0.7	1.2	-0.8	0.8	0.8	1.0	0.1	0.9	1.0	1.1	0.9
Ulcerative Colitis (UC)	0.3	0.5	3.0	-1.7	-0.6	-0.0	-0.2	-0.2	-0.6	-0.3	0.1	1.0
Rheumatoid Arthritis	0.3	0.4	1.6	-1.3	0.3	0.2	0.3	1.2	-0.1	0.3	0.6	0.2
Systolic Blood Pressure	0.3	1.7	3.5	0.9	-1.0	-1.2	-1.4	-1.9	-1.2	-1.3	-1.6	-0.6
Type 2 Diabetes (T2D) (2018)	0.3	0.6	2.7	0.3	0.3	-0.2	0.1	-1.6	0.4	0.2	-0.9	1.0
Hair Pigment	0.3	9.0	30.4	-1.3	1.8	1.9	2.4	4.5	1.2	1.9	5.5	-3.4
Angina	0.3	0.4	0.9	-0.5	-0.6	-0.9	-0.6	-0.5	-0.6	-0.6	-0.4	0.2
Vitamin and mineral supplements	0.3	0.5	1.4	-1.2	-1.2	-0.1	-0.4	0.1	-0.8	-0.7	0.2	-0.4
Medication: Co-codamol	0.3	0.4	2.3	-1.5	-0.3	0.1	-0.0	0.6	-0.6	-0.3	0.6	-0.2
Serious illness, injury or assault to yourself	0.3	0.4	1.1	0.9	1.0	0.2	0.5	0.6	0.6	0.5	0.4	-0.3
Medication: Atenolol	0.3	0.4	1.5	0.5	0.4	-1.2	0.4	-0.3	0.6	0.4	0.7	-0.6
Medication: Levothyroxine sodium	0.3	0.6	1.6	1.3	0.9	1.2	0.3	0.4	0.8	0.3	0.2	0.1
Hearing difficulty/problems with background noise	0.3	0.5	2.3	1.5	0.6	0.3	0.2	-0.3	0.7	0.4	-0.2	-0.6
Diabetes (self-reported)	0.3	0.4	1.2	-0.1	0.7	-0.3	0.3	-1.1	0.5	0.3	-0.6	1.1
Hayfever/allergic rhinitis (self-reported)	0.3	0.4	1.0	0.6	-0.5	-0.6	-0.8	-0.4	-0.6	-0.6	-1.0	0.1
Arm fat mass (right)	0.3	1.0	4.1	0.2	1.0	0.6	0.8	2.0	0.7	0.7	0.1	1.5
Mouth/teeth dental problems: Bleeding gums	0.3	0.4	0.7	0.8	0.8	0.5	0.5	0.6	0.7	0.7	0.3	0.2
Arm fat-free mass (right)	0.3	1.3	8.5	-1.1	0.5	-0.1	0.6	2.9	0.1	0.4	0.6	1.0
Number of full brothers	0.3	0.4	1.8	-0.7	0.3	0.3	0.6	-0.2	0.2	0.3	1.4	-0.9
Number of children fathered	0.3	0.3	0.8	0.9	0.8	-0.0	0.1	-0.0	0.7	0.2	-0.6	0.8
Angina (self-reported)	0.3	0.5	1.0	-0.4	-0.6	-1.0	-0.7	-0.8	-0.7	-0.7	-0.6	0.2
Heart disease (mother)	0.3	0.3	1.5	0.5	-0.2	0.2	0.2	-1.2	0.5	0.1	-0.8	0.4
Comparative height size at age 10	0.3	1.5	5.9	0.1	0.9	0.8	0.9	2.4	0.8	1.0	-0.5	1.8
Had major operations	0.3	0.3	0.9	0.6	-0.2	-0.0	-0.8	0.2	-0.5	-0.7	-1.0	-0.0
Knee pain experienced in last month	0.3	0.5	2.3	-0.0	-0.7	-1.5	-0.6	-0.2	-0.5	-0.6	-0.5	-0.5
Forced expiratory volume in 1-second (FEV1), predicted	0.3	0.6	2.3	1.5	1.2	0.2	0.3	-0.0	0.8	0.5	-0.8	0.4
Ever had bowel cancer screening	0.3	0.3	1.4	-1.2	-0.0	0.0	0.0	0.4	-0.3	0.0	1.2	-0.2
Mineral and other dietary supplements	0.3	0.3	1.3	0.8	-0.7	-0.4	-0.2	-1.1	0.3	-0.1	-0.7	0.1
Osteoporosis (self-reported)	0.3	0.3	0.6	-0.1	0.7	0.8	0.7	0.2	0.7	0.7	0.4	0.5
Arm fat mass (left)	0.3	1.2	4.3	0.1	1.0	0.8	1.0	2.1	0.9	0.9	0.3	1.6
Tinnitus: Yes, now most or all of the time	0.3	0.3	1.6	-0.0	-0.2	0.3	-0.3	0.4	-0.7	-0.5	0.2	-1.3
Basal metabolic rate	0.3	1.4	7.0	-0.2	0.9	0.5	0.7	2.6	0.4	0.6	-0.3	1.9
Arm fat-free mass (left)	0.3	1.6	10.7	-1.1	0.5	0.2	0.7	3.3	0.1	0.4	0.6	1.1
Risk taking	0.3	0.4	1.3	-1.1	-0.6	0.5	0.3	1.2	-0.1	-0.1	0.7	-0.2
Age started oral contraceptive pill	0.3	0.4	1.1	1.1	0.3	0.2	0.2	-0.9	0.7	0.6	0.5	-0.7
Medication: Omeprazole (e.g. Zanprol)	0.3	0.4	1.9	0.8	0.3	0.6	-0.0	-1.4	0.1	-0.1	-0.7	0.5
Heart attack/myocardial infarction (self-reported)	0.3	0.4	2.4	-1.5	-0.5	-0.1	0.0	0.2	-0.4	-0.2	0.9	-0.2
Arm predicted mass (left)	0.3	1.4	9.2	-1.1	0.6	0.1	0.6	3.0	-0.1	0.3	0.5	1.1
Bipolar Disorder (2018)	0.2	0.3	1.2	-0.5	0.7	-0.3	0.4	1.1	0.4	0.2	0.3	0.7
Coronary Artery Disease (CAD)	0.2	0.3	0.6	0.8	-0.0	-0.7	-0.5	-0.5	-0.1	-0.3	-0.6	-0.7
Fasting Glucose	0.2	0.2	0.8	0.8	-0.4	0.4	0.0	0.1	0.5	0.2	-0.9	0.5
Triglycerides	0.2	0.3	0.6	0.2	-0.7	-0.3	-0.8	-0.2	-0.7	-0.7	-0.6	-0.3
Frequency of depressed mood in last 2 weeks	0.2	0.2	1.6	0.3	0.1	0.3	0.1	-1.3	0.2	0.2	-0.2	-0.0
Medication for hormone replacement therapy	0.2	0.3	1.3	1.1	0.5	0.2	0.2	-0.7	0.3	0.2	-0.1	-0.6
Supplements: Zinc	0.2	0.3	1.6	-0.1	0.3	-0.6	0.3	1.3	0.1	0.2	0.4	0.1
Severe depression (siblings)	0.2	0.2	0.6	0.4	-0.0	-0.3	-0.2	-0.8	-0.2	-0.3	-0.6	-0.7
Trunk fat percentage	0.2	0.9	3.6	1.9	0.8	0.6	0.5	0.7	1.1	0.7	-0.7	0.7
Frequency of unenthusiasm / disinterest in last 2 weeks	0.2	0.3	0.9	-0.3	-1.0	-0.3	-0.4	-0.5	-0.6	-0.7	-0.2	-0.7
Tinnitus: Yes, but not now, but have in the past	0.2	0.2	0.5	-0.2	-0.1	0.6	0.4	0.5	0.2	0.3	0.7	-0.7
Trunk fat mass	0.2	0.8	3.0	1.7	0.6	0.5	0.4	1.0	0.8	0.5	-1.0	0.9
Waist circumference	0.2	0.6	2.3	1.0	0.0	0.5	-0.3	0.4	-0.2	-0.3	-1.5	1.3
Frequency of tenseness / restlessness in last 2 weeks	0.2	0.3	1.8	0.5	-0.5	-0.5	0.2	-1.3	0.5	0.4	-0.2	0.2
Forced vital capacity (FVC)	0.2	0.9	2.4	0.7	0.7	0.0	1.1	1.6	1.2	1.0	1.0	-0.6
Heart attack	0.2	0.3	1.8	-1.3	-0.5	0.0	-0.1	0.1	-0.4	-0.2	0.5	0.1
Illnesses of siblings	0.2	0.2	0.6	-0.3	0.2	-0.5	0.3	0.7	0.5	0.3	0.3	0.8
Weight	0.2	1.1	4.6	0.3	1.0	0.6	0.6	2.1	0.6	0.6	-0.5	1.8
Alcohol intake versus 10 years previously	0.2	0.2	0.8	-0.7	-0.2	-0.9	-0.1	0.1	-0.2	-0.2	0.6	-0.6
Forced expiratory volume in 1-second (FEV1)	0.2	0.5	1.7	-0.1	0.5	0.4	0.9	1.3	0.9	0.8	0.6	0.2
Illnesses of mother	0.2	0.3	0.7	0.1	-0.1	-0.7	-0.8	0.0	-0.7	-0.7	-0.7	0.1
Tense / ‘highly strung’	0.2	0.4	1.7	-1.3	-0.4	-0.2	-0.0	0.2	-0.4	-0.1	0.2	1.0
Seen doctor (GP) for nerves, anxiety, tension or depression	0.2	0.3	1.0	-0.7	-0.4	0.2	-0.6	-0.4	-1.0	-0.7	0.0	-0.3
Peak expiratory flow (PEF)	0.2	0.6	2.3	-1.5	-0.7	0.0	-0.3	1.1	-0.8	-0.7	-0.1	0.3
Pulse wave reflection index	0.2	0.3	1.3	0.2	0.2	1.1	0.6	0.1	0.7	0.5	0.1	0.3
Forced vital capacity (FVC), Best measure	0.2	0.7	2.2	1.5	-0.6	-1.2	-0.1	0.6	0.3	-0.2	-0.6	-1.1
Seen a psychiatrist for nerves, anxiety, tension or depression	0.2	0.2	0.6	0.2	-0.5	0.3	-0.5	-0.0	-0.6	-0.7	-0.4	-0.8
Migraine (self-reported)	0.2	0.2	0.7	-0.5	0.6	0.5	0.4	0.3	0.0	0.2	0.8	0.3
Mean time to correctly identify matches	0.2	0.4	1.6	0.2	0.6	1.3	0.4	0.1	0.4	0.4	-0.2	1.0
Arm predicted mass (right)	0.2	1.3	8.3	-1.2	0.3	-0.1	0.6	2.9	-0.0	0.3	0.5	1.0
Chest pain or discomfort	0.2	0.2	0.6	0.8	0.7	0.5	0.3	-0.6	0.5	0.5	0.2	-0.0
Whole body fat-free mass	0.2	1.2	6.0	-0.3	0.7	0.4	0.6	2.4	0.3	0.5	-0.4	1.9
Arm fat percentage (left)	0.2	0.7	1.9	0.3	0.8	0.6	0.7	1.4	0.7	0.6	-0.0	1.4
Diabetes diagnosed by doctor	0.2	0.4	1.0	-0.3	1.0	0.3	0.5	-0.7	0.7	0.6	-0.1	1.0
Whole body water mass	0.2	1.3	6.7	-0.4	0.7	0.3	0.6	2.6	0.2	0.5	-0.4	1.8
Medication: Lisinopril	0.2	0.2	0.9	1.0	0.3	-0.0	0.4	-0.2	0.6	0.5	-0.2	0.0
Average weekly beer plus cider intake	0.2	0.4	1.5	0.6	-0.0	-0.6	-0.0	-1.0	-0.1	-0.2	-0.2	-1.2
Diastolic blood pressure, automated reading	0.2	0.5	1.4	0.9	0.7	-0.6	0.2	1.2	0.4	0.3	0.4	-1.0
Commuting to job workplace: Cycle	0.2	0.3	0.6	-0.3	-0.8	0.2	-0.6	-0.2	-0.8	-0.6	-0.6	0.3
Cholesterol lowering medication	0.2	0.3	0.7	0.2	-0.2	-0.6	-0.8	0.0	-0.7	-0.7	-0.8	0.6
Supplements: Calcium	0.2	0.2	0.5	-0.2	0.4	0.5	0.5	0.0	0.5	0.7	0.4	0.4
Neuroticism (Nagel 2018)	0.1	0.2	0.7	-0.8	-0.2	-0.1	0.0	0.5	-0.6	-0.2	0.5	-0.6
Reaction Time	0.1	0.3	1.2	0.4	0.1	0.6	-0.1	0.0	-0.1	-0.1	-0.9	1.1
Blood Platelet Count	0.1	1.6	4.4	-0.4	-1.2	0.8	-0.7	-2.1	-1.2	-1.2	0.4	-1.9
Hypothyroidism (self reported)	0.1	0.3	0.5	0.6	0.1	-0.1	0.5	0.4	0.7	0.4	0.7	-0.7
Number of treatments/medications taken	0.1	0.1	0.4	-0.2	-0.5	-0.1	-0.4	-0.2	-0.7	-0.4	0.1	-0.4
Other serious medical condition/disability diagnosed by doctor	0.1	0.1	0.2	0.3	-0.4	-0.3	-0.3	0.4	-0.3	-0.4	-0.2	-0.2
Maternal smoking around birth	0.1	0.1	0.4	0.6	0.6	0.2	0.0	0.2	-0.1	-0.0	-0.2	0.3
Taking other prescription medications	0.1	0.1	0.5	-0.1	-0.2	0.7	-0.1	0.2	-0.3	-0.2	0.4	-0.5
High blood pressure (mother)	0.1	0.2	1.0	-1.0	0.1	0.0	0.3	-0.3	0.0	0.2	0.3	0.7
Ever unenthusiastic/disinterested for a whole week	0.1	0.1	0.2	-0.5	0.3	-0.2	0.2	0.3	0.1	0.0	0.3	0.3
Financial difficulties in last 2 years	0.1	0.2	0.8	-0.1	0.0	-0.3	-0.2	0.6	-0.4	-0.4	-0.1	-0.9
Neuroticism score	0.1	0.3	0.5	-0.7	0.2	0.5	0.6	0.3	0.2	0.6	0.7	0.5
Arm fat percentage (right)	0.1	0.5	1.5	0.3	0.6	0.5	0.3	1.2	0.3	0.3	-0.3	1.2
Trunk fat-free mass	0.1	0.6	3.4	-0.1	0.3	-0.1	0.1	1.8	-0.1	0.1	-0.8	1.2
Worrier / anxious feelings	0.1	0.2	1.1	-1.1	-0.1	-0.1	-0.3	0.1	-0.6	-0.3	-0.0	0.7
Number of live births	0.1	0.2	0.5	-0.7	-0.2	0.4	-0.1	-0.7	-0.4	-0.4	0.2	-0.1
Noisy workplace	0.1	0.1	0.4	-0.4	0.0	0.5	0.1	0.6	-0.1	-0.1	0.1	-0.1
Medication: Ibuprofen (e.g. Nurofen)	0.1	0.1	0.3	-0.1	-0.4	-0.6	-0.2	0.2	-0.4	-0.3	0.1	-0.3
Forced expiratory volume in 1-second (FEV1), Best measure	0.1	0.2	0.5	0.0	-0.7	-0.6	-0.0	0.4	0.1	-0.2	-0.7	0.4
Trunk predicted mass	0.1	0.6	3.3	-0.1	0.2	-0.1	0.1	1.8	-0.1	0.0	-0.8	1.3
Headache pain in last month	0.1	0.2	0.9	-0.4	1.0	0.5	0.3	-0.6	0.0	0.2	0.1	0.5
Hypothyroidism/myxoedema (self-reported)	0.1	0.2	0.5	0.7	0.4	0.6	0.4	0.4	0.7	0.3	0.3	0.2
Birth weight	0.1	0.3	0.7	-0.3	0.1	-0.1	0.7	0.7	0.7	0.4	0.1	0.8
High blood pressure (siblings)	0.1	0.2	0.6	0.1	-0.1	0.8	-0.3	-0.7	-0.5	-0.3	-0.2	-0.3
Body fat percentage	0.1	0.5	1.3	1.1	0.6	0.6	0.5	0.8	0.8	0.5	-0.3	0.6
Medication for pain relief, constipation, heartburn	0.1	0.1	0.3	-0.4	0.1	-0.0	0.3	-0.4	0.5	0.2	-0.2	0.5
Whole body fat mass	0.1	0.6	1.3	0.9	0.6	0.5	0.5	1.1	0.7	0.5	-0.5	1.0
Leg fat mass (right)	0.1	0.5	2.4	0.0	0.5	0.9	0.6	1.5	0.4	0.4	0.3	0.8
Illnesses of father: Heart disease	0.1	0.2	0.4	-0.3	-0.4	0.7	-0.2	-0.7	-0.4	-0.3	-0.2	0.5
Illnesses of siblings: Diabetes	0.1	0.2	0.4	0.6	0.3	0.6	-0.1	-0.6	0.2	0.1	-0.3	0.0
Loneliness, isolation	0.1	0.2	0.7	0.6	0.0	-0.3	-0.2	-0.8	-0.1	-0.2	-0.4	-0.3
Osteoarthritis (self-reported)	0.1	0.1	0.4	-0.6	0.1	0.3	0.3	0.4	-0.2	0.2	0.4	0.3
Leg fat percentage (left)	0.1	0.2	1.1	-0.0	-0.2	0.3	-0.0	1.1	-0.3	-0.3	0.3	-0.5
Number of operations (self-reported)	0.1	0.1	0.4	-0.0	0.5	0.4	0.2	0.1	0.4	0.3	0.0	0.7
Ever depressed for a whole week	0.1	0.2	0.8	0.2	0.9	-0.2	0.4	-0.1	0.5	0.4	0.5	-0.0
Heart disease (siblings)	0.1	0.1	0.2	-0.2	0.1	0.2	0.3	0.4	0.3	0.5	0.3	-0.4
Alcohol drinker status: Previous	0.1	0.1	0.4	-0.1	-0.6	0.5	0.3	-0.4	0.0	-0.0	0.4	-0.5
Leg fat mass (left)	0.1	0.6	2.9	-0.1	0.5	0.9	0.6	1.7	0.3	0.4	0.4	0.6
Neuroticism	0.0	0.1	0.3	-0.1	-0.5	-0.0	-0.1	0.1	-0.3	-0.2	-0.1	0.1
Average weekly spirits intake	0.0	0.0	0.1	-0.1	-0.1	-0.0	0.2	0.0	0.2	0.2	0.2	0.2
Systolic blood pressure, automated reading	0.0	0.1	0.6	0.4	0.8	-0.2	0.2	0.2	0.2	0.3	0.4	-0.3
Leg fat percentage (right)	0.0	0.1	0.5	0.2	-0.2	0.3	-0.0	0.7	-0.2	-0.3	0.2	-0.3
Long-standing illness, disability or infirmity	0.0	0.0	0.1	0.1	0.0	0.3	-0.0	0.2	-0.1	-0.2	0.0	0.0
Pain experienced in last month	0.0	0.1	0.2	0.4	-0.4	0.2	-0.2	0.1	-0.1	-0.1	-0.4	-0.3

Hub : Genes

PPP2R5A

Models

Trait associations