TWAS hub - PPP5C

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.135	0.0420	6.8e-04	0.064	NA	0.101	NA	0.092	6.1e-06	NA	1.2e-08	NA	5.8e-08
2	GTEx	Adipose Visceral Omentum	0.185	0.0640	1.5e-03	0.040	NA	0.053	NA	0.048	3.6e-03	NA	1.0e-03	NA	1.7e-03
3	GTEx	Artery Aorta	0.195	0.0630	1.3e-03	0.013	NA	0.002	NA	0.008	6.1e-02	NA	2.4e-01	NA	1.1e-01
4	GTEx	Artery Tibial	0.329	0.0533	1.7e-10	0.235	NA	0.208	NA	0.233	2.4e-18	NA	3.2e-16	NA	3.3e-18
5	GTEx	Breast Mammary Tissue	0.190	0.0640	5.2e-03	-0.006	NA	0.050	NA	0.000	9.8e-01	NA	1.4e-03	NA	3.0e-01
6	GTEx	Breast Mammary Tissue (Female)	0.237	0.1095	4.1e-02	0.011	NA	0.019	NA	0.013	1.5e-01	NA	8.7e-02	NA	1.3e-01
7	GTEx	Esophagus Muscularis	0.133	0.0480	6.2e-03	0.026	NA	0.031	NA	0.055	9.8e-03	NA	5.6e-03	NA	2.8e-04
8	GTEx	Spleen	0.329	0.1050	5.7e-03	0.439	NA	0.420	NA	0.434	1.2e-12	NA	5.1e-12	NA	1.8e-12
9	GTEx	Whole Blood	0.160	0.0470	3.1e-04	0.118	NA	0.121	NA	0.109	5.0e-11	NA	3.0e-11	NA	3.0e-10
10	METSIM	Adipose	0.228	0.0352	1.1e-16	0.175	0.139	0.171	0.173	0.180	2.3e-25	3.1e-20	7.2e-25	4.1e-25	3.8e-26
11	TCGA	Thyroid Carcinoma	0.056	0.0250	2.4e-03	0.032	0.013	0.014	NA	0.010	4.1e-04	1.9e-02	1.4e-02	NA	3.4e-02

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11
Mouth/teeth dental problems: Mouth ulcers	24.0	38.1	74.8	-7.1	-5.5	-3.2	-3.0	-4.8	-2.3	-4.7	-7.9	-8.1	-8.0	-8.6
Crohns Disease (2017)	4.5	9.9	29.9	3.8	2.8	-1.2	-0.8	2.2	1.3	-1.5	5.1	3.6	5.5	2.6
Pain type(s) experienced in last month: Hip pain	3.7	4.6	12.2	3.5	-0.2	-0.7	-0.5	-0.2	-1.1	-0.1	3.3	2.9	3.3	2.5
Prospective memory result	3.6	4.4	7.6	2.6	1.3	1.7	2.7	1.0	0.9	2.8	1.9	2.5	1.9	2.6
Back pain experienced in last month	3.6	5.3	13.1	3.6	1.0	-0.9	-1.0	-1.5	-2.0	-0.8	3.4	2.6	3.3	2.5
Alzheimer’s Disease (in mother)	3.4	4.0	7.4	-2.4	-2.7	1.7	1.5	1.2	1.8	1.9	-2.4	-1.6	-2.4	-1.9
Irritable Bowel Disease (IBD)	3.4	8.2	21.5	3.3	2.2	-1.4	-1.1	1.9	1.4	-2.9	4.3	3.9	4.6	1.7
Pulse rate	3.4	5.7	12.2	2.2	2.9	2.3	3.0	1.2	1.1	3.5	2.4	2.6	2.3	1.7
Hearing difficulty/problems: Yes	3.3	5.1	10.7	2.7	0.8	-1.0	-0.6	2.8	1.7	-0.4	3.2	3.3	3.0	2.4
Crohns Disease (2012)	3.2	5.2	14.1	2.9	2.2	-1.3	-1.1	1.9	0.0	-1.5	3.5	2.3	3.8	2.1
Hearing difficulty/problems with background noise	3.2	5.1	11.8	2.4	1.8	0.2	0.5	1.6	2.1	0.0	3.4	3.1	3.3	2.7
Ever had bowel cancer screening	3.2	3.8	8.2	2.8	1.0	-0.8	-1.0	1.7	1.1	-1.3	2.9	2.2	2.6	2.4
Alzheimer’s Disease (including proxy)	2.8	4.0	10.0	-2.1	-1.8	1.9	1.8	2.8	3.2	1.4	-1.8	-1.3	-1.7	-1.5
LDL Cholesterol	2.8	4.4	10.6	2.4	2.1	0.4	0.8	1.4	-0.4	1.1	3.2	2.9	3.2	2.1
High cholesterol (Self-reported)	2.7	4.8	9.7	2.7	2.3	0.6	0.5	2.2	1.5	0.6	3.0	2.8	3.1	2.5
Lupus	2.6	4.0	11.3	-2.4	-0.3	-0.1	0.7	-0.7	1.5	-0.2	-2.9	-2.5	-3.0	-3.4
Medication: Atorvastatin	2.6	3.2	6.8	2.1	0.9	1.9	1.6	0.3	1.5	1.1	2.5	1.8	2.6	2.1
Pain experienced in last month	2.6	4.3	12.5	-3.5	-0.3	0.2	0.5	-0.4	2.0	-0.1	-2.9	-2.3	-2.9	-2.8
Chronotype (morning person)	2.5	5.9	15.2	3.9	1.6	1.5	1.8	0.2	-1.5	3.7	2.7	2.4	2.6	2.4
Had other major operations	2.4	2.9	8.0	-2.2	-0.1	-0.3	-0.2	-2.8	-1.6	-0.2	-2.1	-1.9	-2.0	-2.0
Mouth/teeth dental problems	2.4	3.7	7.3	2.0	1.3	0.1	-0.2	2.3	2.0	-0.1	2.6	2.7	2.3	2.3
Medication: Aspirin	2.4	3.1	5.3	-2.2	-1.8	-2.0	-2.3	0.7	-0.4	-1.9	-1.7	-2.0	-1.5	-1.7
Supplements: Glucosamine	2.3	3.0	9.4	-1.2	-0.3	-1.7	-0.5	-1.7	-0.6	-1.4	-1.9	-2.2	-2.3	-3.1
Serious illness, injury or assault of a close relative in last 2 years	2.3	2.7	6.8	-1.8	-1.2	-2.1	-2.2	-0.6	-1.0	-2.6	-1.3	-0.9	-1.6	-1.5
Blood Eosinophil Count	2.2	17.3	41.9	4.8	4.0	1.7	1.5	3.3	1.2	3.0	6.0	4.8	6.5	4.8
Supplements: Zinc	2.2	2.3	5.3	-1.7	-1.7	0.6	0.9	0.1	-0.2	-0.4	-2.0	-2.1	-2.2	-2.3
Multivitamins +/- minerals	2.2	2.8	7.0	-2.1	-0.7	-0.6	-0.2	-1.2	-0.4	-0.9	-2.4	-2.2	-2.5	-2.6
Medication: Lansoprazole	2.2	2.5	4.9	1.5	1.1	-1.4	-1.5	1.3	-1.1	-0.9	2.2	2.1	2.2	1.2
Eye problems/disorders: Glaucoma	2.2	2.6	6.9	2.0	2.0	0.2	0.4	0.6	-0.2	0.4	2.5	1.7	2.6	2.1
Depression (self-reported)	2.1	2.5	6.6	2.1	0.6	-1.2	-0.2	0.8	0.1	-0.2	2.5	2.4	2.6	1.4
Heart disease (mother)	2.1	2.6	5.2	-0.8	-1.8	-0.8	-1.3	-2.3	-1.9	-1.7	-1.6	-2.0	-1.7	-1.3
Medication: Aspirin	2.1	2.8	5.4	-2.3	-1.6	-1.8	-2.2	0.5	-0.5	-1.6	-1.7	-1.8	-1.5	-1.7
Mother’s age at death	2.1	2.6	6.6	1.2	1.6	-0.8	-0.1	2.1	0.5	-0.1	2.5	1.9	2.6	1.8
Alcohol drinker status: Never	2.0	2.4	7.6	-2.1	-0.4	-2.1	-2.8	-1.1	-0.7	-2.1	-1.2	0.3	-1.2	-0.9
Medication: Omeprazole (e.g. Zanprol)	2.0	2.5	5.7	1.9	1.6	-2.0	-1.2	-0.4	-0.6	-1.0	2.4	1.3	2.4	1.2
Medication: Cholesterol lowering	1.8	2.8	6.6	1.8	0.9	-1.2	-0.9	1.4	1.6	-1.1	2.5	1.9	2.6	1.4
Medication: Omeprazole	1.8	2.2	4.8	1.8	2.2	-1.4	-0.3	0.9	0.5	-0.2	2.2	1.5	2.1	1.1
Knee pain experienced in last month	1.8	2.9	8.0	2.8	1.4	0.1	0.2	-0.2	-2.4	-0.1	2.4	1.9	2.3	1.2
Qualifications: nursing, teaching	1.8	2.8	7.3	1.4	0.7	-1.4	-2.7	-0.9	-1.8	-2.7	1.4	1.0	1.4	1.6
Financial difficulties in last 2 years	1.7	2.3	7.0	2.3	0.6	1.1	2.6	1.2	1.2	1.7	1.9	0.1	1.5	0.1
Pulse rate, automated reading	1.7	5.4	10.7	2.5	3.3	1.3	2.6	1.7	0.2	2.9	2.6	2.6	2.7	1.4
Triglycerides	1.6	2.6	7.2	1.7	1.0	0.1	-0.3	-0.7	-0.9	-0.3	2.4	2.7	2.3	2.1
Medication: Co-codamol	1.6	1.9	3.2	1.8	1.6	1.1	1.3	-0.0	-0.9	1.7	1.6	0.9	1.5	1.6
Maternal smoking around birth	1.6	2.3	4.7	1.7	-0.2	1.4	1.4	1.0	-0.7	1.2	2.0	1.6	1.9	2.2
Medication: Simvastatin	1.6	2.3	5.7	0.9	1.4	-2.4	-2.4	0.7	0.1	-2.1	1.7	1.1	1.5	0.4
Peak expiratory flow (PEF)	1.6	3.8	9.7	1.7	0.9	-0.8	-0.9	1.4	0.5	-1.5	3.0	2.3	2.8	3.1
Major Depression (MDD)	1.5	1.8	4.1	-1.9	1.1	-0.6	-0.5	0.5	0.9	-1.1	-2.0	-1.3	-1.9	-1.8
Mean Putamen Volume	1.5	1.7	4.8	0.1	-0.4	1.5	2.2	1.9	1.7	1.5	0.9	0.5	1.0	0.7
Blood Red Count	1.5	14.4	30.7	4.8	3.1	-0.4	0.9	4.4	3.3	-0.8	5.5	4.6	5.3	3.8
Medication: Levothyroxine sodium	1.5	2.6	7.1	-2.7	-0.7	0.4	0.3	1.0	1.2	-0.1	-2.4	-2.5	-2.2	-1.3
Illnesses of siblings: Diabetes	1.5	1.9	4.7	1.3	1.2	0.7	0.7	1.8	1.5	-0.2	1.7	0.9	1.7	2.2
Friendships satisfaction	1.5	1.8	6.4	1.1	0.1	-1.7	-0.8	2.5	1.7	-0.9	1.4	0.9	1.4	0.6
Commuting to job workplace: Walk	1.5	1.6	5.1	-0.9	-0.7	1.0	0.9	0.1	2.2	0.0	-1.8	-1.4	-1.7	-1.3
Glaucoma (self-reported)	1.4	1.6	3.6	1.6	1.3	0.5	0.3	0.4	-0.9	0.6	1.7	1.3	1.9	1.9
Comparative body size at age 10	1.4	3.8	9.1	-3.0	-2.9	1.0	0.2	-2.2	-0.7	0.6	-2.7	-1.6	-2.5	-1.0
Number of full brothers	1.4	1.7	6.8	0.6	0.2	1.7	2.2	0.5	0.4	2.6	0.8	1.3	0.8	1.1
Seen a psychiatrist for nerves, anxiety, tension or depression	1.4	1.8	4.7	1.8	0.3	0.5	0.9	1.0	0.2	0.9	2.2	1.7	2.0	1.5
Osteoarthritis (self-reported)	1.4	1.9	6.2	2.5	1.6	0.1	0.1	-0.4	0.6	-0.8	1.9	0.8	1.8	1.6
Illnesses of father: None of the above (group 1)	1.4	1.7	6.0	1.6	2.4	-1.7	-1.9	0.9	-0.5	-0.4	0.9	0.7	0.7	0.9
Rheumatoid Arthritis	1.3	1.7	4.0	-1.3	-1.8	-0.5	-0.3	-0.7	-1.4	0.3	-1.7	-2.0	-1.9	-1.1
Medication for cholesterol, blood pressure or diabetes	1.3	2.1	4.8	-1.9	-1.2	1.2	0.9	-1.1	-0.1	0.5	-2.1	-2.2	-2.2	-0.6
Neck or shoulder pain in last month	1.3	1.8	3.5	1.3	1.9	-0.8	-1.2	-0.2	-0.9	-1.3	1.8	1.1	1.6	1.7
Medication: Allopurinol	1.3	1.8	5.2	-0.5	-2.3	0.2	0.5	1.3	0.5	0.3	-1.4	-1.9	-1.4	-2.1
Average weekly champagne plus white wine intake	1.3	1.7	5.0	-1.3	-2.2	0.2	0.2	0.2	-0.6	0.5	-1.8	-1.6	-1.9	-1.5
Ever taken oral contraceptive pill	1.3	1.4	4.0	-0.3	-0.2	1.6	1.5	-0.5	2.0	0.3	-1.3	-0.6	-1.3	-1.5
Hearing aid user	1.3	1.5	5.6	0.8	-0.7	-1.3	-0.5	1.5	2.4	-0.6	1.1	1.5	1.1	0.9
Number of operations (self-reported)	1.3	2.0	5.2	-2.3	-0.2	1.3	1.1	0.5	1.0	1.0	-1.5	-1.7	-1.7	-1.7
Blood White Count	1.2	9.1	20.1	-4.5	-4.0	0.8	0.4	-2.4	-0.4	-0.3	-4.2	-3.9	-4.0	-3.1
Ever had hysterectomy (womb removed)	1.2	1.3	4.5	1.0	0.5	1.6	1.6	2.1	0.8	0.9	0.6	0.6	0.4	1.2
Diabetes (mother)	1.2	1.5	4.4	1.3	1.3	-0.8	-0.2	0.3	-0.1	-0.1	2.1	1.8	2.0	1.2
Tinnitus: Yes, but not now, but have in the past	1.2	1.3	3.0	-1.7	0.4	-1.3	-0.9	-0.8	-1.6	-0.9	-1.0	-0.9	-0.8	-1.6
Happiness	1.2	1.4	5.5	1.3	0.4	-2.3	-1.6	1.5	0.3	-0.8	1.1	0.9	1.0	-0.1
Noisy workplace	1.2	1.5	5.7	0.9	1.1	-2.4	-1.4	0.2	-0.1	-0.8	1.3	1.2	1.1	1.3
Pulse wave reflection index	1.2	1.5	4.4	-0.7	-1.1	-0.3	-1.0	-2.1	-0.6	-1.6	-1.6	-1.3	-1.5	-0.5
Long-standing illness, disability or infirmity	1.2	1.9	4.6	1.1	1.0	-1.3	-1.4	-0.1	-2.2	-0.4	1.5	1.8	1.6	1.3
Cholesterol lowering medication	1.2	1.8	6.1	1.3	2.5	0.1	-0.6	0.4	-0.2	-0.5	1.6	2.0	1.4	1.5
Ulcerative Colitis (UC)	1.1	2.1	7.5	1.4	0.9	-0.9	-0.7	0.5	1.1	-2.7	1.6	2.1	1.8	0.3
Medication for hormone replacement therapy	1.1	1.3	4.0	-0.6	-1.7	0.1	-0.3	-0.8	-0.1	-0.9	-1.4	-2.0	-1.5	-1.0
Vitamin and mineral supplements	1.1	1.4	3.6	1.3	0.2	-0.0	-0.4	1.2	0.7	0.4	1.6	1.6	1.7	1.9
Average weekly fortified wine intake	1.1	1.3	3.4	-1.8	-1.3	-0.5	-0.0	-1.4	-0.2	-0.5	-1.2	-0.8	-1.4	-1.6
Ever unenthusiastic/disinterested for a whole week	1.1	1.4	6.2	-0.8	-2.5	-1.6	-1.2	-0.3	-1.2	-0.8	-0.5	-1.2	-0.5	-0.5
Frequency of tiredness / lethargy in last 2 weeks	1.1	1.8	3.5	1.9	0.8	-1.7	-1.4	-0.8	-1.2	-1.2	1.3	1.9	1.0	0.8
Mouth/teeth dental problems: Bleeding gums	1.1	1.4	4.5	-0.8	0.1	-0.2	0.4	-1.8	-2.1	0.2	-1.2	-1.0	-1.2	-1.6
Medication: Ventolin 100micrograms inhaler	1.1	1.4	5.4	-0.7	-1.4	0.1	0.3	-2.3	-1.3	0.4	-1.2	-1.4	-1.3	-0.9
Chronic bronchitis/emphysema (mother)	1.1	1.3	4.5	-2.1	-1.3	0.3	0.4	-0.8	-1.0	0.7	-1.4	-0.9	-1.1	-1.0
Suffer from ‘nerves’	1.1	1.8	4.5	0.4	1.0	-1.2	-1.3	-1.7	0.4	-1.2	1.7	2.1	1.4	1.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.1	1.3	3.9	0.6	-0.2	-1.2	-1.4	-0.1	-0.7	-1.7	1.0	2.0	1.2	0.6
Handedness (chirality/laterality): Left-handed	1.1	1.3	2.8	-0.9	-0.9	1.0	0.4	0.2	1.5	0.1	-1.7	-1.7	-1.6	-1.2
Ever had stillbirth, spontaneous miscarriage or termination	1.1	1.2	2.8	-1.7	-1.6	-1.0	-1.4	0.3	0.5	-0.8	-0.7	-0.7	-0.7	-1.4
Wears glasses or contact lenses	1.1	1.3	3.5	-1.1	0.4	-1.1	-1.6	-1.7	-0.7	-1.9	-0.6	-0.8	-0.8	-0.2
Commuting to job workplace: Public transport	1.1	1.3	3.6	-0.6	0.3	-0.7	-0.8	-1.9	-0.9	-1.3	-1.5	-0.8	-1.8	-0.9
Alzheimer’s Disease (in father)	1.0	1.0	4.8	-0.3	-0.2	0.8	1.0	2.2	2.0	0.5	-0.2	-0.7	-0.0	0.1
Respiratory disease	1.0	2.2	4.0	1.8	1.4	-0.1	0.3	-1.7	-1.4	0.8	1.9	1.9	1.7	2.0
Pain all over the body in last month	1.0	1.1	3.4	-1.7	-0.6	-0.5	-1.0	1.9	0.2	-0.3	-1.2	-0.9	-1.1	0.1
Gout (self-reported)	1.0	1.4	4.3	-0.8	-2.1	0.2	0.3	1.6	0.6	0.5	-1.0	-1.4	-0.9	-1.8
Birth weight	1.0	2.2	5.6	1.9	2.4	0.5	0.8	-0.0	0.2	-0.3	1.8	2.1	2.0	1.6
Myopia	1.0	1.5	3.0	-0.6	-1.1	-0.7	-1.5	-1.5	-1.7	-1.7	-1.1	-0.6	-1.1	-1.1
Allergy or Eczema	0.9	2.4	5.4	1.5	1.6	0.2	0.1	1.4	-0.3	1.3	2.1	2.1	2.3	1.8
Current tobacco smoking	0.9	1.4	3.5	-1.8	-1.9	0.3	0.6	0.8	-0.1	1.4	-1.1	-1.3	-0.8	-1.5
Lung cancer (father)	0.9	1.1	4.2	0.3	1.1	-1.3	-1.2	-0.5	-2.0	-0.7	0.9	1.0	0.9	-0.2
Pulse wave Arterial Stiffness index	0.9	1.1	2.0	1.2	1.4	1.2	1.2	1.1	1.4	0.2	0.4	0.7	0.4	1.2
Exposure to tobacco smoke at home	0.9	1.0	2.3	0.7	0.6	1.0	0.9	-1.3	-1.5	1.0	0.7	1.4	0.9	0.6
Wheeze or whistling in the chest in last year	0.9	1.7	4.0	-1.0	-1.4	0.7	0.8	-2.0	-1.9	1.0	-1.4	-1.1	-1.2	-1.0
Number of children fathered	0.9	1.0	5.8	-0.7	0.0	1.4	1.5	0.0	-0.4	2.4	0.2	-0.5	0.1	0.5
Pulse wave peak to peak time	0.9	1.1	2.5	-0.8	-1.3	-1.3	-1.3	-1.4	-1.6	-0.4	-0.1	-0.4	-0.1	-1.0
Smoking status: Current	0.9	1.4	3.8	-1.7	-1.9	0.1	0.4	1.0	-0.2	1.4	-1.0	-1.1	-0.7	-1.4
Body Mass Index (BMI) (2010)	0.8	1.1	1.8	-1.2	-1.2	-1.3	-1.4	-0.7	-0.1	-1.2	-1.4	-0.5	-1.3	-0.7
Schizophrenia (2014)	0.8	1.7	3.6	-1.9	-1.3	-1.4	-1.7	1.1	0.3	-1.9	-0.8	-1.0	-0.7	-1.2
Ulcerative Colitis	0.8	1.1	5.1	0.5	0.0	-1.1	-1.1	-0.4	-0.7	-2.2	0.7	1.6	0.8	-0.2
Average weekly spirits intake	0.8	1.0	2.4	1.3	0.9	0.5	0.1	1.0	1.0	0.3	1.3	1.6	1.3	1.1
Age when periods started (menarche)	0.8	1.9	7.5	-0.9	0.3	-0.9	-0.7	-1.8	-2.7	-0.5	-1.1	-0.7	-1.5	-1.8
Bilateral oophorectomy (both ovaries removed)	0.8	0.9	3.1	-0.6	-1.8	0.9	0.3	-0.0	1.0	0.1	-0.9	-1.4	-1.3	-0.4
Number of incorrect matches in round	0.8	1.3	5.0	-0.6	-1.2	1.5	1.7	-0.2	-0.2	2.2	-0.8	-1.3	-0.3	0.1
Hair/balding pattern: Pattern 2	0.8	1.0	4.2	0.3	-2.0	1.4	1.5	-0.3	0.4	1.2	-0.3	-0.7	-0.5	0.3
Time employed in main current job	0.8	1.0	4.8	0.7	0.7	0.2	0.1	-2.2	-1.5	0.1	-1.0	-0.3	-1.2	-0.2
Forced expiratory volume in 1-second (FEV1)	0.8	2.7	6.0	2.0	0.9	-1.2	-1.2	-0.5	-0.5	-1.7	2.4	2.0	2.2	2.0
Medication: Seretide 50 evohaler	0.8	0.9	4.1	1.3	0.6	-0.4	-0.0	-0.1	-0.6	-0.1	1.3	2.0	1.0	1.0
Smoking status: Previous	0.8	1.2	6.0	-0.4	-0.4	-1.4	-2.1	0.6	-0.4	-2.4	-0.1	-0.2	0.3	0.0
Deep venous thrombosis (DVT) (self-reported)	0.8	1.0	2.6	-0.4	0.8	-0.6	-0.2	-0.8	0.8	-1.1	-1.6	-0.3	-1.6	-1.5
Bipolar Disorder (2018)	0.7	1.2	5.6	-1.0	1.6	-0.2	-0.8	2.4	1.2	0.5	-0.4	-0.8	-0.5	0.3
Depression (Nagel 2018)	0.7	1.0	2.5	-0.6	-0.2	-1.6	-1.1	-0.3	0.2	-1.5	-0.8	-0.7	-1.1	-1.5
Fasting Glucose	0.7	0.8	3.2	-0.7	0.0	-0.9	-0.9	-0.5	-1.1	-0.7	-0.6	-0.8	-0.6	-1.8
Primary Biliary Cirrhosis	0.7	1.0	4.1	1.0	0.8	1.8	0.6	0.0	0.4	0.8	0.2	0.7	0.1	2.0
Waist Hip Ratio (WHR)	0.7	3.2	8.5	2.1	2.9	0.2	-0.4	2.5	0.7	0.7	2.0	2.2	2.2	1.2
Angina	0.7	0.9	3.6	-0.7	-1.4	1.0	0.7	0.7	1.1	1.9	-0.0	-0.6	0.2	0.1
Diabetes (father)	0.7	0.9	2.2	-0.9	-0.0	-1.2	-1.3	-1.4	-1.5	-1.2	-0.1	0.1	-0.3	-0.1
Medication: Atenolol	0.7	0.9	4.4	0.9	0.5	2.1	1.2	-0.6	1.0	0.1	0.7	0.4	0.8	0.0
Frequency of tenseness / restlessness in last 2 weeks	0.7	1.1	4.4	1.1	0.4	-2.1	-1.5	-0.5	-0.3	-1.7	0.8	0.1	0.5	-0.4
Diabetes (self-reported)	0.7	1.0	5.5	0.7	0.4	0.2	-0.1	2.4	0.6	0.2	1.2	1.2	1.2	0.7
Medication: Ramipril	0.7	0.9	2.5	-1.6	-1.5	-0.4	-0.6	0.3	-0.2	0.4	-1.4	-0.5	-1.1	-1.1
Number of live births	0.7	1.0	2.7	-1.2	-0.4	0.6	-0.4	1.6	0.3	0.1	-1.4	-1.6	-1.3	0.0
Mouth/teeth dental problems: Dentures	0.7	1.2	3.5	0.4	0.2	1.9	1.6	-0.8	-0.5	1.8	0.2	0.5	0.4	1.5
Forced expiratory volume in 1-second (FEV1), Best measure	0.7	2.2	5.3	2.1	0.7	-0.8	-0.8	0.2	-0.1	-0.5	2.3	1.7	2.2	2.0
Forced vital capacity (FVC), Best measure	0.7	2.7	7.0	2.5	0.4	0.0	0.1	-0.1	0.5	0.1	2.6	1.8	2.6	2.4
Medication: Ibuprofen	0.7	0.8	2.7	0.2	-1.0	1.6	1.4	-0.8	-0.1	1.3	-0.5	-0.8	-0.4	0.0
Chest pain or discomfort	0.7	1.0	3.0	-1.2	-1.0	-1.5	-1.1	-1.1	0.6	-1.7	-0.2	-0.4	-0.3	-0.6
Mineral and other dietary supplements	0.7	1.0	3.6	0.1	-0.2	1.2	1.0	0.6	1.4	1.9	0.6	0.6	0.8	1.0
Age at First Birth	0.6	0.9	2.0	-0.9	-1.1	-0.9	-0.5	-1.0	-0.2	-0.5	-1.1	-0.7	-1.4	-1.0
Lung FVC	0.6	3.0	6.5	1.3	0.0	-1.7	-1.7	1.3	0.8	-1.8	2.6	1.8	2.5	2.0
Systolic blood pressure, automated reading	0.6	1.6	5.1	-1.1	0.1	-2.3	-1.9	0.1	0.0	-2.0	-0.7	-0.8	-0.5	-1.6
Taking other prescription medications	0.6	1.0	1.7	0.9	0.7	-1.1	-1.1	0.9	-0.4	-1.3	1.3	1.0	1.2	0.9
Qualifications: CSEs or equivalent	0.6	0.7	3.3	-0.3	-0.1	-1.5	-0.8	-0.8	-1.8	-0.7	0.3	0.2	0.4	-0.4
Past tobacco smoking	0.6	1.2	3.7	0.4	0.9	1.7	1.9	-1.4	0.2	1.8	-0.3	0.0	-0.7	0.3
Forced vital capacity (FVC)	0.6	2.2	6.2	2.1	0.7	-0.2	-0.2	-1.0	-0.2	-0.7	2.5	1.7	2.2	1.9
Heel bone mineral density (BMD) T-score, automated (right)	0.6	1.3	2.5	-1.4	0.1	0.2	-0.0	-1.2	1.3	-0.9	-1.5	-1.6	-1.5	-0.9
Hayfever/allergic rhinitis (self-reported)	0.6	0.8	2.4	-0.8	-0.2	-0.7	-1.3	-1.0	-1.6	0.0	-1.0	-0.3	-1.1	-0.2
Fluid intelligence score	0.6	1.2	4.3	-0.0	-1.2	0.9	-1.6	-1.5	-1.1	-2.1	-0.2	-0.2	-0.3	0.9
Falls in the last year	0.6	0.9	3.8	-0.1	-0.4	-1.6	-1.4	0.3	-0.6	-2.0	0.1	0.6	0.0	-0.4
Medication: Ibuprofen (e.g. Nurofen)	0.6	0.7	2.1	0.4	-1.3	1.2	1.1	0.2	0.4	0.7	-0.6	-1.4	-0.5	0.1
Loud music exposure frequency	0.6	0.7	2.1	-0.3	-1.3	1.4	1.1	0.6	0.3	1.2	-0.5	-0.3	-0.4	0.1
Qualifications: O levels/GCSEs or equivalent	0.6	0.9	2.9	1.5	-1.5	0.5	0.0	0.6	1.7	0.1	0.8	0.1	0.6	0.9
Blood clot in the leg (DVT)	0.6	0.8	1.8	-0.2	0.6	-0.6	-0.2	-0.7	0.8	-1.2	-1.3	-0.0	-1.4	-1.3
Hypothyroidism/myxoedema (self-reported)	0.6	1.1	3.5	-1.9	0.4	0.6	0.3	0.8	0.4	0.1	-1.6	-1.3	-1.5	-0.5
Eye problems/disorders: None of the above	0.6	0.6	1.8	-0.1	-0.2	-0.4	-0.1	1.4	0.8	-0.3	-1.0	-0.6	-1.2	-1.2
Angina (self-reported)	0.6	0.8	3.4	-0.8	-1.2	0.9	0.7	0.7	1.2	1.9	0.1	-0.5	0.3	0.0
Had major operations	0.6	0.7	1.8	-1.0	-1.1	-0.2	-0.4	0.7	-0.2	-0.3	-0.7	-1.3	-1.0	-0.9
Age at last live birth	0.6	0.9	3.9	0.6	-0.1	0.2	-0.7	1.6	2.0	-1.2	0.1	0.5	-0.1	0.9
Eye problems/disorders: Cataract	0.6	0.7	3.5	-0.5	-0.2	-0.3	-1.0	-1.9	-1.5	-0.8	0.3	-0.3	0.3	-0.1
Asthma (self-reported)	0.6	1.1	4.5	0.8	-0.3	0.5	0.3	-2.1	-2.0	0.7	0.8	0.6	0.8	0.8
Osteoporosis (self-reported)	0.6	0.7	3.1	-0.3	0.1	-1.2	-1.8	0.1	0.5	-1.5	-0.1	-0.6	-0.2	0.2
Medication: Gliclazide	0.6	0.6	1.2	0.7	1.0	-0.6	-1.1	0.5	-0.4	-0.6	0.7	0.9	0.7	1.1
Miserableness	0.6	1.0	3.8	-0.5	-0.2	2.0	1.9	-1.0	0.3	1.4	-0.4	-0.0	-0.6	0.0
Financial situation satisfaction	0.6	0.8	3.1	0.2	-0.2	-1.8	-0.7	1.7	0.4	0.1	-0.5	-0.5	-0.4	-1.1
Medication: Blood pressure	0.6	1.2	3.9	0.8	-0.8	1.8	0.8	-2.0	-0.9	1.1	0.5	0.3	0.4	1.5
Ever smoked	0.6	1.0	2.8	-0.3	-1.2	-1.7	-1.6	1.2	0.2	-1.5	0.2	-0.0	0.4	-0.7
Average weekly beer plus cider intake	0.6	0.9	1.7	0.9	0.3	1.1	1.3	-0.3	-0.4	1.1	1.3	0.9	1.3	0.5
Risk taking	0.6	0.9	6.1	-0.4	-2.5	0.5	0.4	0.5	0.6	0.1	-0.7	-1.0	-0.8	-0.4
Ever had prostate specific antigen (PSA) test	0.6	0.6	1.7	0.1	0.5	-0.8	-0.4	1.3	0.7	-0.8	0.8	0.9	0.8	1.1
Supplements: Calcium	0.6	0.7	2.4	-0.8	0.8	-1.0	-1.3	0.3	-0.2	-1.6	-0.4	-0.4	-0.5	-0.6
Pack years of smoking	0.6	0.9	2.8	0.9	0.7	-0.2	-0.1	-1.3	-1.7	0.3	0.7	1.5	0.5	1.0
Bipolar Disorder or Schizophrenia	0.5	1.2	3.2	-1.6	0.7	-1.1	-1.8	1.6	1.3	-1.2	-0.1	-0.5	0.1	-0.2
Schizophrenia (2018)	0.5	1.0	4.0	-1.2	-0.4	-1.3	-1.7	0.2	0.7	-2.0	0.3	0.0	0.5	-0.5
Verbal and Numeric Reasoning (VNR)	0.5	1.1	3.9	0.2	-1.3	0.1	-2.0	-1.2	-0.7	-2.0	0.1	-0.2	-0.3	0.5
Systolic Blood Pressure	0.5	2.3	5.1	-1.4	-1.0	-0.5	-0.7	-1.6	0.5	-0.7	-2.2	-2.0	-2.0	-2.3
Type 2 Diabetes (T2D) (2018)	0.5	0.9	1.7	0.3	1.0	0.7	-0.0	1.3	0.5	0.5	1.3	1.1	1.3	1.2
Other serious medical condition/disability diagnosed by doctor	0.5	0.7	1.5	1.0	1.2	-0.7	-0.2	-0.1	0.4	0.6	1.2	0.9	1.0	0.5
Eye problems/disorders: Diabetes related eye disease	0.5	0.5	2.1	-1.4	-0.6	0.0	-0.9	-0.6	0.1	-1.3	-0.6	-0.1	-0.6	-0.1
Severe depression (siblings)	0.5	0.6	2.5	0.8	1.6	-0.7	0.5	0.9	-0.2	-0.4	0.7	0.8	0.7	-0.2
Pack years adult smoking proportion	0.5	0.8	3.5	0.5	0.5	-0.2	-0.2	-1.5	-1.9	0.3	0.4	1.1	0.2	0.8
Frequency of unenthusiasm / disinterest in last 2 weeks	0.5	0.7	2.1	-0.5	-0.5	-1.2	-0.9	-1.4	-0.7	-1.0	-0.4	-0.2	-0.7	-0.8
Relative age voice broke	0.5	0.8	2.1	-1.5	-1.4	0.4	0.1	-0.5	-0.6	0.6	-1.2	-0.2	-1.3	-0.5
Heel bone mineral density (BMD) T-score, automated (left)	0.5	1.2	2.6	-1.6	-0.5	0.2	0.2	-1.6	0.9	-0.6	-1.3	-1.6	-1.3	-1.0
Serious illness, injury or assault to yourself	0.5	0.6	3.0	0.8	-0.6	0.7	0.3	-0.4	-1.7	1.2	0.0	0.5	0.1	0.5
Chronic bronchitis/emphysema (father)	0.5	0.5	1.4	0.9	-0.1	-0.3	0.4	0.4	0.3	0.4	1.2	1.1	1.2	0.6
Had menopause	0.5	0.6	2.2	-0.4	0.6	-1.1	-1.0	-0.1	-1.3	-1.5	0.2	-0.0	0.2	-0.6
Hair/balding pattern: Pattern 3	0.5	0.8	2.1	0.5	1.4	-0.3	-0.7	-0.1	-1.5	0.8	1.0	0.6	1.1	0.6
Asthma	0.5	1.0	4.9	0.6	-0.2	0.2	0.0	-2.2	-2.1	0.4	0.5	0.3	0.5	0.6
Illnesses of mother	0.5	0.6	2.0	1.2	0.5	0.3	0.1	0.5	0.1	0.6	0.9	0.7	0.9	1.4
Length of working week for main job	0.5	0.5	3.0	0.1	0.0	-0.7	0.6	1.7	1.3	0.5	0.0	-0.1	0.2	-0.4
Ever highly irritable/argumentative for 2 days	0.5	0.6	2.2	-0.4	-0.8	-1.5	-0.6	-0.6	-1.2	-0.5	0.3	-0.6	0.4	-0.7
Medication: Paracetamol	0.5	0.9	2.7	1.2	1.2	1.6	1.4	0.2	-0.2	-0.1	0.7	-0.0	0.7	1.2
Exposure to tobacco smoke outside home	0.5	0.7	2.7	0.2	0.3	1.6	1.1	0.7	-0.1	1.6	-0.4	-0.3	-0.2	-0.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.5	0.6	1.8	1.3	-0.6	-0.3	0.5	1.3	0.1	-0.4	1.0	0.3	1.0	-0.2
Illness, injury, bereavement, stress in last 2 years	0.5	0.7	2.9	-0.1	0.9	0.4	-0.8	-1.1	0.3	-0.8	0.3	0.7	0.4	1.7
Average weekly red wine intake	0.5	0.7	3.2	0.5	-1.8	0.5	0.9	-0.0	1.6	0.4	-0.3	0.1	-0.5	-0.1
Loneliness, isolation	0.5	0.7	2.1	-0.2	0.4	-1.2	-1.0	-1.4	-0.2	-1.5	-0.1	0.6	-0.3	-0.3
Breast cancer (self-reported)	0.5	0.6	2.5	0.5	0.9	0.6	0.4	-0.9	-0.1	1.6	-0.3	-1.0	-0.3	0.3
Number of self-reported non-cancer illnesses	0.5	0.8	1.9	1.3	0.9	-0.4	-0.6	0.4	-0.5	-0.1	1.2	1.2	1.4	1.0
Guilty feelings	0.5	0.8	2.5	-0.6	-0.5	-1.2	-1.2	-1.3	-0.9	-1.6	0.3	0.4	0.1	0.4
Supplements: Fish oil (including cod liver oil)	0.5	0.6	2.0	0.2	0.4	-1.0	-1.1	0.3	-1.4	-1.4	0.1	0.7	0.1	0.3
Medication: Lisinopril	0.5	0.6	2.2	0.7	-0.1	0.2	0.3	-1.5	-1.4	0.3	0.2	-0.2	0.1	-1.2
Irritability	0.5	0.8	1.8	1.3	0.3	-0.6	-0.9	-0.4	-0.9	-0.6	1.3	1.3	0.9	0.8
Heart disease (siblings)	0.5	0.6	2.3	0.8	-0.3	1.3	1.5	0.5	0.5	1.0	0.4	0.1	0.3	0.4
Alcohol drinker status: Previous	0.5	0.6	2.8	-0.5	-0.8	0.4	0.1	-0.4	-0.7	-0.1	-1.2	0.2	-0.9	-1.7
Intelligence (Savage-Jansen 2018)	0.4	1.1	5.7	0.4	-1.1	-0.5	-1.8	-0.4	0.8	-2.4	0.5	-0.0	0.2	0.8
Schizophrenia vs Biploar Disorder	0.4	0.5	1.2	0.8	-0.9	-0.8	0.1	0.2	0.6	-1.1	0.3	0.1	0.4	-1.1
Worry (Nagel 2018)	0.4	0.8	2.8	-0.2	0.5	-1.7	-1.4	-1.1	-0.4	-0.7	0.7	0.5	0.4	-0.8
Breast Cancer	0.4	1.0	4.8	1.0	-0.7	0.4	-0.5	0.8	1.3	-0.4	0.7	1.1	0.7	2.2
Height	0.4	7.2	28.8	2.1	3.9	-0.1	0.9	-5.4	-3.0	-1.5	2.2	3.1	2.0	-0.5
Cardiovascular Disease	0.4	1.2	3.4	1.6	0.2	1.3	0.4	-0.1	0.1	0.6	1.7	0.7	1.9	1.2
Sensitivity / hurt feelings	0.4	0.6	2.4	-0.1	-0.3	1.0	1.6	-0.3	-0.0	1.4	-0.0	0.9	-0.3	0.3
Medication: Metformin	0.4	0.6	2.5	-1.6	-0.8	-0.5	-0.4	0.2	-0.6	-0.1	-0.6	0.0	-0.5	-1.3
Nervous feelings	0.4	0.8	2.3	0.3	0.6	-1.5	-1.1	-1.1	-0.8	-0.4	1.2	0.6	0.9	0.4
Illnesses of siblings	0.4	0.6	1.5	-0.7	-0.6	-0.9	-1.1	-0.4	-1.2	-0.3	-0.3	-0.1	-0.2	-1.2
Father’s age at death	0.4	0.5	1.3	0.2	0.7	-1.1	-1.1	0.1	-0.9	-0.4	0.4	0.5	0.6	-0.8
Seen doctor (GP) for nerves, anxiety, tension or depression	0.4	0.7	4.2	-0.5	-1.2	0.4	-0.0	2.1	0.8	0.4	0.1	-0.4	-0.1	0.4
High blood pressure (siblings)	0.4	0.6	1.6	0.8	0.8	0.4	1.0	-0.4	0.4	0.2	0.7	1.2	0.6	1.1
Age at first live birth	0.4	0.7	1.8	1.3	-1.0	0.5	-0.2	0.8	1.2	-0.5	0.5	0.4	0.2	1.4
Health satisfaction	0.4	0.5	1.8	0.3	-0.9	-1.3	-0.7	0.2	-0.8	0.1	0.3	1.1	0.6	-0.2
Mouth/teeth dental problems: Loose teeth	0.4	0.5	3.2	-0.2	0.3	0.3	0.9	0.6	-0.2	1.8	-0.3	-0.6	-0.1	-0.0
Alcohol intake frequency.	0.4	0.9	2.6	0.0	1.1	-1.6	-1.2	0.0	-1.2	-1.2	0.3	1.3	0.4	0.1
Comparative height size at age 10	0.4	2.4	9.1	0.4	1.4	0.0	-0.3	-3.0	-2.3	-1.8	1.2	1.7	1.4	0.4
Number of full sisters	0.4	0.5	1.5	-0.2	1.2	-0.4	-0.2	-0.4	0.8	-1.2	0.5	0.0	0.6	0.9
Leg pain on walking	0.4	0.5	1.3	-0.3	-0.7	0.3	1.1	0.9	-0.9	1.0	-0.3	0.3	-0.1	-0.6
Supplements: Vitamin C	0.4	0.5	2.2	0.3	0.9	0.7	1.0	-0.2	-1.5	1.0	0.0	-0.1	-0.0	-0.3
Illnesses of father: Heart disease	0.4	0.5	4.2	-0.6	-2.0	0.2	-0.4	-0.4	-0.4	-0.8	-0.3	0.0	-0.4	-0.1
Diabetes diagnosed by doctor	0.4	0.6	4.4	-0.1	0.4	0.2	-0.3	2.1	0.5	-0.1	0.6	0.9	0.7	0.3
Medication for cholesterol	0.4	0.7	2.1	-1.0	1.1	-1.3	-0.3	1.5	0.3	-0.2	-0.2	0.1	-0.1	-1.1
Tinnitus: Yes, now most or all of the time	0.4	0.5	2.1	-0.2	0.8	0.7	0.4	0.7	1.4	-1.0	-0.1	-0.3	-0.1	0.6
Medication: Paracetamol	0.4	0.7	1.4	1.1	0.8	1.1	0.9	-0.2	-0.2	-0.4	1.0	0.4	0.9	1.2
Heel T-Score	0.3	2.5	8.1	-2.0	-0.3	1.3	1.2	-0.1	2.9	1.0	-1.9	-1.8	-1.6	-1.0
Smoking Status	0.3	0.7	2.4	-1.5	-0.7	-0.7	-0.4	1.6	-0.0	0.2	-0.6	-0.4	0.0	-1.1
Hypothyroidism (self reported)	0.3	0.6	1.5	-1.0	1.0	0.9	0.2	0.5	0.3	0.1	-1.2	-0.7	-1.2	0.0
Neuroticism	0.3	0.6	3.8	0.5	-0.0	-0.3	-0.1	-0.4	0.0	-0.1	1.3	1.9	1.0	0.0
Ever used hormone-replacement therapy (HRT)	0.3	0.4	2.9	-0.0	-1.7	-0.3	0.0	-0.3	-0.3	-0.7	-0.4	-0.3	-0.4	-0.8
Leg fat-free mass (left)	0.3	1.6	7.7	-0.6	0.2	-0.0	0.3	-2.8	-1.9	-0.8	-1.2	0.2	-1.0	-1.5
Townsend deprivation index at recruitment	0.3	0.4	1.6	-0.1	0.1	0.4	1.3	0.4	0.0	1.1	0.2	0.7	0.4	-0.7
Hayfever, allergic rhinitis or eczema	0.3	0.6	1.6	0.3	0.4	0.5	0.0	0.4	-0.9	0.9	0.7	1.0	0.8	1.3
Diverticular disease/diverticulitis (self-reported)	0.3	0.4	1.9	0.8	1.4	-0.4	-0.4	-0.3	-0.7	0.2	0.3	0.8	0.2	0.4
High blood pressure (mother)	0.3	0.4	1.3	-0.3	0.5	0.3	0.9	-0.8	-1.1	-0.7	0.3	-0.2	0.2	-0.4
Leg predicted mass (left)	0.3	1.5	7.5	-0.6	0.2	-0.1	0.1	-2.7	-1.9	-0.9	-1.1	0.3	-0.9	-1.4
Waist circumference	0.3	0.9	2.9	0.3	1.4	-0.6	-0.9	0.2	-1.5	-0.7	0.6	1.7	1.0	0.1
Qualifications: None of the above	0.3	0.6	2.1	-0.5	1.4	-0.9	-0.5	0.7	0.1	0.8	0.4	0.6	0.9	0.7
Allergy	0.3	0.6	2.1	-0.4	-0.2	-0.9	-0.4	1.1	1.5	-1.0	-0.1	-0.9	-0.3	-0.9
Neuroticism score	0.3	0.6	2.8	0.5	0.3	-0.1	0.1	-0.4	-0.4	0.3	1.3	1.7	1.0	0.5
Alcohol intake versus 10 years previously	0.3	0.5	1.2	0.4	-0.1	-1.0	-0.4	0.3	1.1	-0.1	0.9	0.5	1.1	0.2
Standing height	0.3	2.5	17.8	1.0	1.4	0.4	0.4	-4.2	-2.0	-1.1	0.5	1.0	0.3	-0.3
Breastfed as a baby	0.3	0.4	1.4	0.6	0.6	0.8	0.2	0.9	1.2	0.1	-0.4	0.3	-0.4	0.6
Worry too long after embarrassment	0.3	0.5	2.0	-0.4	-0.7	0.2	0.7	0.1	-0.4	1.4	0.7	1.3	0.4	0.3
Reason for reducing amount of alcohol drunk: Health precaution	0.3	0.3	1.2	-0.2	-0.0	1.1	0.5	-0.5	-0.6	0.1	-0.4	-1.0	-0.4	0.0
Qualifications: College or University degree	0.3	0.9	3.6	-0.2	-1.9	1.2	-0.6	-0.9	0.2	-1.0	-1.0	-1.0	-1.1	0.1
Family relationship satisfaction	0.3	0.3	0.9	0.5	-0.7	-0.9	-0.3	0.8	0.4	-0.4	0.1	0.4	0.2	-0.9
Commuting to job workplace: Car/motor vehicle	0.3	0.3	1.6	-0.2	0.4	-0.2	-0.7	0.5	-1.3	0.4	0.6	0.4	0.7	-0.2
Leg fat-free mass (right)	0.3	1.7	8.2	-0.7	0.2	-0.1	0.0	-2.9	-2.2	-0.8	-1.2	0.2	-1.1	-1.5
Mood swings	0.3	0.6	2.2	0.7	-0.7	0.6	-0.3	-0.0	-0.5	0.4	1.0	0.5	0.9	1.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.3	0.6	2.6	0.6	0.0	-1.1	-0.8	-0.6	0.8	-1.6	0.6	-0.4	0.5	0.4
Leg predicted mass (right)	0.3	1.6	7.7	-0.6	0.2	-0.1	0.0	-2.8	-2.1	-0.7	-1.2	0.2	-1.0	-1.4
Medication: Bendroflumethiazide	0.3	0.5	1.3	-0.9	-0.9	0.4	-0.5	-0.3	-0.1	0.1	-1.2	-0.7	-1.0	-0.7
Illnesses of father: High blood pressure	0.3	0.4	1.3	-0.2	-0.6	0.4	1.1	-0.7	0.8	-0.4	0.2	-0.4	0.2	-1.1
Age started oral contraceptive pill	0.3	0.4	1.6	-0.2	-0.2	-0.8	-0.2	0.4	0.4	-0.9	-0.5	-0.6	-0.6	-1.3
Diastolic blood pressure, automated reading	0.3	0.9	3.8	0.6	2.0	-0.3	0.9	1.2	0.7	0.5	1.0	0.5	1.2	-0.4
Ever depressed for a whole week	0.3	0.3	0.8	-0.5	-0.9	-0.5	-0.3	0.8	0.3	-0.0	-0.7	-0.7	-0.5	-0.4
Unable to work because of sickness or disability	0.3	0.4	2.4	-0.1	0.6	0.1	0.8	0.4	0.1	1.6	0.4	0.5	0.4	0.0
Heart attack/myocardial infarction (self-reported)	0.3	0.4	1.2	-0.3	-1.1	0.7	0.1	-0.7	-0.2	0.0	0.8	0.4	0.9	0.5
Neuroticism (Nagel 2018)	0.2	0.6	1.6	-0.8	0.0	-1.2	-1.3	-1.0	0.5	-1.0	0.1	0.5	-0.2	-0.3
Ovarian Cancer	0.2	0.3	1.8	0.6	0.0	0.3	0.5	-1.3	-0.2	-0.3	0.2	0.7	0.1	0.6
HbA1C	0.2	0.2	0.9	0.9	0.9	0.1	-0.2	0.3	-0.4	0.4	0.2	0.6	0.1	0.4
HDL Cholesterol	0.2	0.4	0.9	-0.4	-0.1	0.1	0.3	0.8	1.0	0.8	-0.7	-0.6	-0.9	-0.5
Neuroticism (2016)	0.2	0.3	1.5	0.4	0.5	0.7	0.8	-0.2	1.2	-0.0	-0.1	0.5	0.1	-0.2
Lung FEV1/FVC ratio	0.2	0.8	2.6	-0.9	-1.0	-0.6	-0.9	0.7	0.8	-1.6	-0.8	0.0	-0.6	-1.2
Hand grip strength (left)	0.2	0.6	2.7	0.7	0.0	-0.8	-0.0	-0.2	-0.1	-0.1	1.3	1.1	1.6	0.0
Number of treatments/medications taken	0.2	0.4	1.0	0.9	0.0	-0.1	-0.7	-0.3	-1.0	-0.7	0.5	0.5	0.6	0.9
Frequency of depressed mood in last 2 weeks	0.2	0.2	1.4	0.0	-0.2	-1.2	-0.4	0.7	-0.1	-0.5	0.0	-0.2	-0.2	-0.3
Impedance of leg (right)	0.2	0.8	2.2	0.8	0.4	0.4	-0.2	1.1	0.6	0.1	1.5	0.1	1.4	1.5
Stomach or abdominal pain in last month	0.2	0.3	0.8	-0.0	0.4	0.5	0.6	0.2	-0.8	0.9	-0.3	0.4	-0.4	0.4
Impedance of leg (left)	0.2	0.9	3.3	0.8	0.4	0.1	-0.6	1.0	0.1	0.1	1.6	0.1	1.4	1.8
Heart attack	0.2	0.3	1.3	-0.4	-1.1	0.2	-0.3	-0.7	-0.1	-0.4	0.6	0.4	0.8	0.3
Weight	0.2	1.0	4.7	0.1	0.7	-0.1	-0.2	-1.9	-2.2	-1.0	-0.2	1.0	0.2	-0.4
Trunk fat-free mass	0.2	1.0	6.2	0.4	1.1	-0.0	0.4	-2.5	-1.0	-0.9	0.1	0.9	0.3	-0.6
Qualifications: A levels/AS levels or equivalent	0.2	0.4	1.9	1.4	-0.7	0.1	-0.8	0.3	0.5	-0.1	0.5	0.4	0.3	0.8
Trunk predicted mass	0.2	0.9	5.8	0.5	1.1	0.2	0.5	-2.4	-0.9	-0.8	0.1	0.9	0.3	-0.5
Tense / ‘highly strung’	0.2	0.3	0.9	0.6	-0.1	-0.3	-0.1	0.1	-0.2	-0.2	0.9	1.0	0.9	-0.2
Headache pain in last month	0.2	0.4	1.3	1.1	0.9	-0.2	0.1	0.5	0.0	-0.5	1.1	0.2	0.8	0.3
Medication: Amlodipine	0.2	0.2	1.4	-1.2	-0.5	0.2	-0.1	0.0	0.1	0.2	-0.6	-0.1	-0.6	-0.4
Arm fat-free mass (right)	0.2	0.8	3.7	-0.2	0.5	-0.5	-0.2	-1.9	-1.6	-1.1	-0.3	0.4	-0.1	-1.0
Shortness of breath walking on level ground	0.2	0.3	0.6	-0.4	-0.3	0.1	0.4	-0.5	-0.8	-0.6	-0.6	-0.3	-0.5	-0.6
Emphysema/chronic bronchitis	0.2	0.3	1.1	-1.1	-0.7	0.7	0.3	-0.3	-0.2	0.1	-0.2	-0.7	-0.1	-0.0
Medication for pain relief, constipation, heartburn	0.2	0.3	1.7	0.0	0.5	-0.8	-0.1	-0.1	0.3	0.8	0.4	1.3	0.1	-0.0
Medication: Blood pressure	0.2	0.3	1.3	0.2	-0.4	-0.6	-0.7	-0.5	-0.9	-0.2	-0.0	0.5	-0.0	-1.1
Migraine (self-reported)	0.2	0.2	1.2	-0.0	1.1	-0.5	-0.2	-0.3	0.0	-0.5	-0.4	-0.1	-0.2	-0.7
Mean time to correctly identify matches	0.2	0.3	0.9	0.6	0.7	-1.0	-0.4	0.2	-0.0	-0.7	0.5	0.8	0.4	0.3
Overall health rating	0.2	0.5	1.3	-0.3	1.1	-1.0	-1.1	0.7	0.4	-1.1	-0.2	0.1	-0.2	-0.3
Qualifications: NVQ or HND or HNC or equivalent	0.2	0.2	0.6	0.7	0.5	-0.3	0.8	0.5	-0.3	0.4	0.4	0.1	0.2	-0.1
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.4	1.7	0.1	0.2	1.3	1.2	-0.3	0.6	1.1	-0.1	-0.2	-0.1	-0.2
Whole body fat-free mass	0.2	1.1	7.3	-0.2	0.7	0.0	0.3	-2.7	-1.4	-0.9	-0.6	0.4	-0.4	-1.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.2	0.3	0.9	1.0	0.8	0.2	0.1	-0.3	-0.2	-0.3	0.7	0.5	0.8	-0.0
Whole body water mass	0.2	1.2	7.4	-0.2	0.7	0.0	0.3	-2.7	-1.5	-0.9	-0.6	0.4	-0.4	-1.0
Basal metabolic rate	0.2	1.2	6.7	-0.2	0.7	-0.1	0.1	-2.6	-1.7	-1.0	-0.6	0.6	-0.3	-1.0
Arm fat-free mass (left)	0.2	1.0	5.1	-0.0	0.8	-0.4	-0.0	-2.3	-1.6	-1.1	-0.3	0.6	-0.0	-0.9
Fractured/broken bones in last 5 years	0.2	0.3	0.8	0.3	-0.1	0.9	0.8	-0.7	-0.4	0.6	0.1	-0.3	-0.0	0.4
Commuting to job workplace: Cycle	0.2	0.3	0.8	-0.3	-0.8	-0.8	-0.5	-0.5	-0.9	0.1	-0.1	0.2	-0.0	0.6
Arm predicted mass (left)	0.2	1.0	5.6	-0.0	0.6	-0.2	-0.0	-2.4	-1.5	-1.2	-0.3	0.5	-0.1	-0.8
Depressed Affect (Nagel 2018)	0.1	0.2	1.4	-0.4	-0.3	0.1	-0.3	-0.6	1.2	-0.4	-0.1	0.4	-0.4	0.1
Reaction Time	0.1	0.3	0.9	0.3	0.0	-1.0	-0.7	-0.1	-0.7	-0.7	-0.1	0.4	-0.2	0.0
Prostate Cancer	0.1	0.2	0.9	0.3	0.1	-0.0	-0.1	-0.5	-0.0	0.3	-0.4	-1.0	-0.6	0.2
Type 2 Diabetes (T2D) (2012)	0.1	0.2	0.5	0.2	0.6	0.5	0.3	-0.1	-0.3	0.4	0.3	0.5	0.7	0.2
Blood Platelet Count	0.1	0.8	4.2	0.5	0.4	-0.0	0.4	-2.0	-1.2	0.5	0.6	0.9	1.0	-0.3
BMI	0.1	0.8	1.7	-0.8	-0.9	0.8	0.6	-0.6	-1.0	0.2	-1.3	-1.2	-0.9	-1.3
Tanning	0.1	1.2	4.2	0.2	-0.0	1.6	2.1	0.9	1.4	1.2	0.8	-0.2	0.8	0.8
Relative age of first facial hair	0.1	0.3	0.9	-0.5	0.3	0.7	0.5	0.8	-0.4	0.9	-0.2	-0.1	-0.2	0.3
Trunk fat percentage	0.1	0.5	2.6	-0.8	-0.5	0.2	-0.5	0.1	-1.6	-0.7	-0.6	0.3	-0.3	0.2
Hand grip strength (right)	0.1	0.3	1.0	0.1	-0.0	-0.6	0.0	-0.8	-0.9	0.0	0.6	0.5	1.0	-0.4
Fed-up feelings	0.1	0.2	0.6	0.1	-0.7	0.7	0.3	-0.7	-0.3	0.5	0.4	0.4	0.2	0.5
High blood pressure	0.1	0.4	1.3	0.1	-0.9	0.5	0.0	-1.1	-0.7	-0.1	-0.5	-0.5	-0.5	-0.7
Sitting height	0.1	1.1	6.6	-0.1	1.0	0.7	1.1	-2.6	-0.5	0.2	-0.6	-0.4	-0.6	-1.0
Body mass index (BMI)	0.1	0.3	1.5	-0.5	-0.0	-0.3	-0.4	0.2	-1.2	-0.4	-0.5	0.5	-0.0	-0.3
Trunk fat mass	0.1	0.5	2.8	-0.5	-0.2	0.1	-0.4	-0.6	-1.7	-1.0	-0.4	0.7	-0.1	-0.0
Impedance of arm (right)	0.1	0.3	1.4	-0.1	-0.5	1.2	0.6	-0.1	0.2	0.7	0.1	-0.4	-0.2	0.8
Arm fat percentage (right)	0.1	0.3	1.0	-1.0	-0.3	0.0	-0.4	0.2	-0.9	-0.7	-0.7	0.4	-0.4	-0.0
Hip circumference	0.1	0.4	2.2	-0.2	0.4	0.2	0.1	-0.9	-1.5	-0.2	0.1	0.9	0.3	0.2
Worrier / anxious feelings	0.1	0.3	0.8	0.5	0.9	-0.1	-0.3	-0.1	-0.9	0.4	0.4	0.6	0.3	-0.1
Impedance of arm (left)	0.1	0.3	1.1	-0.1	-0.6	1.0	0.4	0.3	-0.1	0.8	0.2	-0.3	-0.2	0.9
Arm fat mass (right)	0.1	0.3	1.7	-0.6	-0.0	-0.0	-0.3	-0.4	-1.3	-0.8	-0.4	0.7	-0.0	0.0
Hair/balding pattern: Pattern 4	0.1	0.2	0.8	0.6	0.6	-0.2	-0.1	-0.9	-0.2	0.0	-0.1	0.3	0.0	-0.9
Birth weight of first child	0.1	0.3	1.0	0.8	0.7	0.4	0.5	0.1	0.5	-0.1	0.2	0.1	0.2	1.0
Body fat percentage	0.1	0.3	2.0	-0.6	-0.1	0.2	-0.4	0.3	-1.4	-0.6	-0.2	0.6	0.1	0.4
Leg fat percentage (right)	0.1	0.3	0.9	-0.1	0.3	-0.0	-0.4	0.7	-0.9	-0.5	0.1	0.7	0.5	0.4
Whole body fat mass	0.1	0.4	2.7	-0.5	-0.0	0.1	-0.3	-0.5	-1.6	-0.9	-0.3	0.8	0.0	-0.1
Leg fat mass (right)	0.1	0.5	2.9	-0.2	0.3	-0.1	-0.2	-0.6	-1.7	-0.6	-0.1	1.0	0.3	0.1
Arm predicted mass (right)	0.1	0.7	3.7	-0.1	0.6	0.0	0.2	-1.9	-1.4	-0.7	-0.5	0.4	-0.2	-0.8
Hypertension (Self-reported)	0.1	0.2	0.8	0.5	-0.9	0.4	-0.1	-0.8	-0.3	-0.2	-0.2	-0.4	-0.2	-0.3
Arm fat percentage (left)	0.1	0.3	1.3	-0.8	-0.4	-0.1	-0.5	0.4	-1.1	-0.5	-0.5	0.5	-0.2	0.1
Arm fat mass (left)	0.1	0.5	2.2	-0.7	0.1	-0.4	-0.6	-0.6	-1.5	-1.1	-0.4	0.6	-0.0	-0.2
Leg fat percentage (left)	0.1	0.3	1.4	-0.2	0.3	-0.2	-0.5	0.7	-1.2	-0.5	0.1	0.7	0.5	0.4
Vascular/heart problems diagnosed by doctor	0.1	0.3	1.3	-0.3	1.0	-0.7	-0.3	1.2	0.6	-0.2	0.0	0.3	-0.0	0.3
Basal cell carcinoma (self-reported)	0.1	0.2	0.5	0.1	-0.7	0.2	0.1	-0.6	-0.5	-0.6	-0.2	-0.1	-0.4	-0.0
Impedance of whole body	0.1	0.3	1.3	0.1	-0.6	0.8	0.0	0.7	-0.0	0.6	0.4	-0.4	0.2	1.1
Leg fat mass (left)	0.1	0.5	3.5	-0.3	0.2	-0.2	-0.3	-0.6	-1.9	-0.6	-0.1	0.9	0.3	0.0
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Coronary Artery Disease (CAD)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Hair Pigment	0.0	1.4	2.8	1.2	0.9	-0.5	-1.2	1.2	0.0	-0.8	1.3	1.6	1.3	1.7
Alcohol usually taken with meals	0.0	0.1	0.3	0.5	0.3	-0.1	-0.2	0.6	0.2	-0.0	-0.1	0.1	-0.1	0.0

Hub : Genes

PPP5C

Models

Trait associations