TWAS hub - PRKAB1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Brain Nucleus accumbens basal ganglia	0.5830	0.1470	7.1e-03	0.057	NA	0.084	NA	0.069	1.2e-02	NA	3.0e-03	NA	6.6e-03
2	GTEx	Cells Transformed fibroblasts	0.2350	0.0790	3.8e-04	0.278	NA	0.313	NA	0.313	4.9e-21	NA	6.1e-24	NA	6.0e-24
3	GTEx	Esophagus Mucosa	0.3830	0.0730	4.4e-09	0.323	NA	0.293	NA	0.321	3.6e-22	NA	6.4e-20	NA	5.4e-22
4	GTEx	Nerve Tibial	0.1095	0.0420	4.8e-04	0.098	NA	0.032	NA	0.066	2.1e-07	NA	2.3e-03	NA	2.1e-05
5	GTEx	Whole Blood	0.1040	0.0340	1.3e-05	0.048	NA	0.045	NA	0.073	3.0e-05	NA	5.0e-05	NA	3.0e-07
6	METSIM	Adipose	0.1096	0.0436	2.0e-03	0.091	0.007	0.077	0.089	0.086	1.9e-13	2.8e-02	1.1e-11	2.7e-13	8.0e-13
7	NTR	Blood	0.0225	0.0107	8.5e-03	0.022	0.002	0.015	0.012	0.020	9.5e-08	5.0e-02	1.1e-05	7.0e-05	4.0e-07
8	YFS	Blood	0.4002	0.0400	0.0e+00	0.174	0.176	0.228	0.229	0.234	1.3e-54	3.2e-55	4.2e-73	1.6e-73	3.9e-75
9	TCGA	Kidney Renal Clear Cell Carcinoma	0.0236	0.0154	3.6e-03	0.009	0.013	0.009	NA	0.009	3.0e-02	1.1e-02	3.2e-02	NA	3.0e-02
10	TCGA	Thyroid Carcinoma	0.0350	0.0230	1.9e-03	0.018	0.026	0.013	NA	0.015	6.8e-03	1.2e-03	1.9e-02	NA	1.1e-02

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10
Number of children fathered	6.2	7.0	11.4	-0.8	3.1	3.0	-2.7	-2.4	3.1	3.4	2.1	2.8	2.1
Systolic blood pressure, automated reading	4.7	13.5	22.8	-0.2	3.5	3.8	-4.5	-4.8	3.5	3.5	1.7	4.5	4.2
Crohns Disease (2017)	4.5	9.8	19.5	-0.4	4.3	4.0	-1.5	-1.4	3.9	4.4	3.5	2.7	2.3
Irritable Bowel Disease (IBD)	3.8	9.0	18.9	-0.1	4.3	4.0	-0.6	-0.8	3.9	4.3	3.8	1.8	1.5
Alcohol intake versus 10 years previously	3.7	5.6	9.9	-0.2	-3.1	-2.6	1.8	1.5	-2.7	-2.8	-2.1	-3.0	-2.4
Blood White Count	3.6	27.0	63.2	-0.4	-7.4	-7.0	0.2	-0.7	-7.4	-6.8	-8.0	-0.2	0.1
Alzheimer’s Disease (in father)	3.5	3.8	7.8	0.7	-2.7	-2.8	1.0	1.3	-2.1	-2.1	-1.9	-1.8	-2.0
Myopia	3.5	5.1	8.6	-0.0	-2.8	-2.7	2.1	1.8	-2.5	-2.9	-1.9	-2.2	-2.2
Coronary Artery Disease (CAD)	3.4	4.1	7.3	0.5	2.4	2.6	0.0	-2.2	1.9	2.7	1.5	2.0	2.5
Crohns Disease (2012)	3.4	5.4	10.8	0.4	3.1	2.9	-1.6	-1.3	2.7	3.3	2.3	2.3	1.8
Schizophrenia (2018)	3.0	6.3	16.2	0.7	0.5	0.1	3.2	4.0	1.1	0.3	2.4	-3.9	-3.7
Medication: Laxatives (e.g. Dulcolax, Senokot)	3.0	3.6	7.8	0.8	-1.9	-2.3	1.9	1.8	-1.9	-2.8	-1.4	-1.7	-1.7
Birth weight of first child	2.9	5.2	9.4	-2.1	1.7	2.1	-2.6	-3.0	1.7	2.1	0.7	3.1	2.7
Family relationship satisfaction	2.9	3.6	9.9	0.6	0.1	0.2	3.0	2.7	0.4	-0.1	1.4	-3.1	-2.8
High cholesterol (Self-reported)	2.9	5.1	13.6	-1.4	0.9	1.1	-3.1	-3.3	0.5	1.0	-0.6	3.7	3.4
Tense / ‘highly strung’	2.8	4.6	11.0	-1.3	-0.7	-1.1	3.3	3.3	-0.7	-1.0	0.8	-3.0	-3.0
Eye problems/disorders: Cataract	2.8	3.3	6.0	1.3	2.5	2.2	-1.1	-1.2	2.2	2.2	1.6	1.7	1.6
Bipolar Disorder or Schizophrenia	2.7	6.6	19.2	1.6	0.4	-0.2	3.6	4.4	0.7	0.1	2.0	-3.7	-3.6
Medication: Atorvastatin	2.7	3.3	9.5	-1.7	0.7	0.6	-1.9	-2.7	0.0	0.3	-0.7	3.1	3.0
Medication: Lisinopril	2.6	3.4	8.2	-0.8	0.5	1.0	-2.8	-2.6	0.2	0.7	-0.8	2.9	2.8
Alcohol intake frequency.	2.5	5.8	9.8	-2.2	-3.1	-2.8	1.8	1.7	-2.8	-2.6	-2.3	-2.2	-2.2
Ulcerative Colitis (UC)	2.4	4.6	10.0	0.2	3.0	3.0	0.0	-0.4	2.9	3.2	2.9	0.8	0.7
Mean time to correctly identify matches	2.4	4.5	10.6	-1.9	-1.3	-1.2	2.3	3.1	-1.0	-1.1	-0.1	-3.2	-3.3
Age at last live birth	2.4	3.5	9.1	-1.6	-0.5	-0.7	2.5	2.5	-0.2	-0.2	0.8	-3.0	-3.0
Illnesses of father: None of the above (group 1)	2.4	3.0	6.7	-0.2	-2.2	-2.2	-0.1	-0.8	-2.4	-2.6	-2.6	0.4	0.5
Wears glasses or contact lenses	2.4	2.7	4.7	-2.2	1.8	1.8	-1.3	-1.3	1.6	1.6	1.4	1.6	1.8
Mother’s age at death	2.4	3.0	9.3	0.2	-0.6	-1.1	2.6	3.0	-0.4	-0.9	0.4	-2.2	-2.4
Risk taking	2.4	3.5	9.0	-0.5	1.0	0.6	2.0	2.4	1.4	0.6	2.2	-3.0	-2.7
Maternal smoking around birth	2.3	3.4	12.4	1.1	-0.3	-0.3	1.7	2.8	0.2	-0.1	1.0	-2.9	-3.5
Handedness (chirality/laterality): Left-handed	2.3	2.7	4.9	-1.4	-1.8	-2.2	1.4	1.6	-2.2	-2.2	-1.3	-1.1	-0.8
Friendships satisfaction	2.3	2.9	5.3	0.9	0.8	1.1	2.3	2.1	1.0	1.1	1.9	-2.3	-2.3
Vascular/heart problems diagnosed by doctor	2.3	6.2	13.5	1.5	-1.6	-2.2	3.3	3.7	-1.3	-1.7	-0.1	-3.4	-3.3
Bipolar Disorder (2011)	2.2	2.2	7.5	2.7	-1.6	-1.6	0.0	1.3	-1.5	-1.2	-1.1	-1.1	-1.1
Qualifications: O levels/GCSEs or equivalent	2.2	3.5	6.8	0.9	-2.4	-2.6	1.5	1.4	-2.1	-2.5	-1.9	-1.2	-1.4
Mouth/teeth dental problems: Loose teeth	2.2	2.6	4.1	1.2	-1.9	-2.0	1.6	1.3	-1.9	-1.7	-1.3	-1.7	-1.4
Reaction Time	2.1	4.1	10.5	-2.0	-1.5	-1.2	1.9	2.8	-1.0	-0.7	-0.3	-3.2	-3.1
Primary Biliary Cirrhosis	2.1	3.0	6.7	0.3	2.6	2.3	-0.2	-0.1	2.2	2.3	2.4	1.2	0.8
Average weekly spirits intake	2.1	2.6	6.9	1.1	0.6	0.9	-2.0	-2.6	0.6	0.4	-0.6	2.4	2.4
High blood pressure	2.1	5.9	12.7	-1.8	1.6	2.1	-3.2	-3.6	1.2	1.5	0.2	3.3	3.4
Mouth/teeth dental problems: Bleeding gums	2.1	2.7	5.3	0.5	-1.3	-1.7	2.2	1.8	-1.4	-1.8	-0.7	-2.3	-1.8
Tinnitus: Yes, now most or all of the time	2.1	2.5	4.4	-0.8	-1.7	-1.9	1.7	1.6	-2.0	-2.1	-1.3	-0.9	-0.9
Depressed Affect (Nagel 2018)	2.0	4.1	11.2	-3.4	2.6	2.4	-1.0	-0.6	1.5	2.3	2.0	1.5	1.6
Multivitamins +/- minerals	2.0	2.6	6.3	-1.7	0.7	1.0	1.6	1.8	1.1	1.0	1.8	-2.0	-2.5
Financial difficulties in last 2 years	2.0	2.7	8.3	0.8	-0.7	-0.5	2.4	2.2	-0.3	-0.8	0.6	-2.9	-2.4
Hypertension (Self-reported)	2.0	5.7	11.8	-2.0	1.6	2.1	-3.1	-3.4	1.2	1.6	0.2	3.2	3.2
Medication: Bendroflumethiazide	2.0	3.0	4.4	-1.5	2.1	2.0	-1.6	-1.2	1.8	1.7	1.5	2.1	1.8
Alcohol drinker status: Previous	2.0	2.3	6.4	-0.9	-1.0	-0.9	1.6	2.1	-0.7	-0.9	-0.2	-2.3	-2.5
Ever unenthusiastic/disinterested for a whole week	1.9	2.4	7.1	0.8	-0.3	-0.6	2.6	2.7	-0.6	-1.1	0.4	-2.0	-1.7
Medication: Cholesterol lowering	1.9	3.0	5.8	-0.2	1.6	1.8	-2.2	-2.0	1.2	1.6	0.4	2.3	2.4
Commuting to job workplace: Walk	1.9	2.1	4.2	-0.8	2.1	1.7	-0.4	-1.0	1.5	1.9	1.7	1.1	1.5
Age started oral contraceptive pill	1.9	2.4	4.4	0.2	2.1	1.9	-1.1	-1.1	1.9	1.5	1.4	1.7	1.7
Schizophrenia (2014)	1.8	4.0	9.6	0.7	0.6	0.2	2.3	3.1	1.0	0.4	2.0	-3.1	-3.0
Seen a psychiatrist for nerves, anxiety, tension or depression	1.8	2.3	4.7	-2.2	1.3	1.0	1.2	1.7	1.0	1.3	2.1	-1.7	-1.3
Ever had prostate specific antigen (PSA) test	1.8	2.0	4.2	1.7	-1.9	-1.7	0.1	-0.4	-1.7	-1.9	-2.1	0.3	0.3
Ulcerative Colitis	1.7	2.5	5.2	0.9	2.0	2.1	0.6	0.3	2.1	2.3	2.3	-0.2	-0.4
Systolic Blood Pressure	1.7	8.7	21.4	-0.2	1.7	2.2	-4.3	-4.6	1.5	1.6	-0.1	4.3	4.1
Vitamin and mineral supplements	1.7	2.3	4.9	0.7	-0.7	-0.6	-2.1	-2.1	-0.9	-0.7	-1.7	2.1	2.2
Mouth/teeth dental problems: Dentures	1.7	3.0	8.5	0.6	-0.6	-0.3	-1.6	-2.5	-1.1	-0.7	-1.8	2.5	2.9
Worry (Nagel 2018)	1.6	3.4	14.2	-3.8	-0.9	-1.5	1.9	2.3	-1.7	-1.4	-0.1	-1.2	-1.3
Serious illness, injury or assault to yourself	1.6	2.0	6.2	-0.8	0.3	0.1	-1.6	-2.2	-0.1	-0.5	-0.9	2.5	2.1
Glaucoma (self-reported)	1.6	1.9	4.4	0.7	-2.1	-1.8	0.5	0.0	-1.8	-1.6	-1.8	-0.9	-0.9
Leg fat percentage (left)	1.6	5.7	13.0	-0.8	1.4	1.5	-3.6	-3.4	1.3	1.7	-0.4	3.4	3.5
Diastolic blood pressure, automated reading	1.6	4.9	13.7	-0.3	1.4	1.7	-3.0	-3.7	1.5	1.5	0.1	3.0	2.9
LDL Cholesterol	1.5	2.4	4.8	-0.8	1.7	1.6	-1.3	-1.7	1.1	1.7	0.8	2.0	2.2
Severe depression (siblings)	1.5	1.7	4.7	0.8	1.4	1.3	0.2	0.7	2.2	1.7	1.8	-0.4	-0.8
Hayfever/allergic rhinitis (self-reported)	1.5	1.9	6.6	-2.6	0.7	0.8	-1.3	-1.6	0.8	1.1	0.0	1.9	1.4
Medication for cholesterol, blood pressure or diabetes	1.5	2.4	6.3	0.2	-1.0	-1.2	2.0	2.3	-0.5	-0.8	0.1	-2.5	-2.3
Leg fat percentage (right)	1.5	5.3	11.4	-1.1	1.3	1.5	-3.4	-3.2	1.3	1.6	-0.3	3.2	3.4
Long-standing illness, disability or infirmity	1.5	2.2	4.1	0.7	1.8	1.9	-1.2	-1.2	1.6	1.2	1.0	1.7	2.0
Mouth/teeth dental problems: Mouth ulcers	1.5	2.4	4.4	-2.1	-1.6	-1.7	0.7	1.2	-1.8	-2.1	-1.1	-1.3	-1.1
Medication for cholesterol	1.5	2.3	4.7	1.7	-1.3	-1.3	1.5	2.0	-1.0	-1.0	-0.5	-2.2	-2.0
Ever depressed for a whole week	1.5	1.8	4.3	-1.0	-0.5	-0.6	2.1	2.1	-0.6	-0.8	0.3	-1.9	-1.8
Basal cell carcinoma (self-reported)	1.5	1.7	3.5	-0.8	-0.9	-1.3	1.9	1.7	-1.0	-0.9	-0.3	-1.9	-1.5
Depression (Nagel 2018)	1.4	2.1	5.1	-1.6	1.9	1.8	0.2	1.3	1.2	1.7	2.3	-0.5	-0.3
Diabetes (father)	1.4	1.8	4.3	0.7	1.9	1.7	0.5	0.5	1.8	1.5	2.1	-0.5	-0.2
Hearing difficulty/problems with background noise	1.4	2.2	4.9	-1.6	-1.4	-1.9	1.5	0.8	-2.0	-2.2	-1.5	-0.5	0.3
Financial situation satisfaction	1.4	1.8	3.5	1.9	-1.5	-1.1	1.1	1.1	-1.4	-1.3	-1.0	-1.4	-1.2
Ovarian Cancer	1.3	1.7	3.4	1.0	-1.7	-1.7	0.8	0.7	-1.7	-1.9	-1.3	-0.7	-0.7
Cardiovascular Disease	1.3	4.2	9.7	-1.3	1.2	1.5	-2.5	-3.1	0.7	1.1	-0.3	3.1	3.1
Qualifications: A levels/AS levels or equivalent	1.3	2.9	7.1	0.5	0.3	-0.2	2.7	2.6	0.5	0.2	1.5	-2.5	-2.5
Eye problems/disorders: None of the above	1.3	1.5	2.5	-1.0	-1.3	-1.5	1.0	1.1	-1.6	-1.6	-0.8	-1.1	-0.9
Cholesterol lowering medication	1.3	2.0	5.2	-0.7	0.3	0.4	-1.9	-2.3	-0.1	0.4	-0.7	2.1	2.2
Fasting Glucose	1.2	1.4	3.6	0.3	-1.4	-1.2	-0.1	-0.9	-1.6	-1.5	-1.9	0.6	0.6
Townsend deprivation index at recruitment	1.2	1.6	3.9	0.5	-1.3	-1.2	1.5	1.3	-1.3	-0.9	-0.8	-2.0	-1.3
Frequency of tenseness / restlessness in last 2 weeks	1.2	1.9	2.9	-1.5	-1.4	-1.4	1.2	1.5	-1.7	-1.7	-1.1	-1.1	-0.8
Heel bone mineral density (BMD) T-score, automated (right)	1.2	2.7	6.9	1.0	-2.2	-2.0	-1.3	-1.5	-1.6	-1.8	-2.6	0.7	0.8
Pain all over the body in last month	1.2	1.3	2.3	-0.3	-0.8	-0.8	-1.3	-1.0	-1.2	-1.3	-1.5	1.1	1.5
Exposure to tobacco smoke at home	1.2	1.3	3.0	-0.7	-1.7	-1.6	-0.0	0.2	-1.6	-1.2	-1.7	-0.4	-0.4
Medication: Blood pressure	1.2	2.0	3.9	-0.2	1.3	1.6	-1.7	-1.8	1.2	1.2	0.4	2.0	1.7
Qualifications: nursing, teaching	1.2	1.9	5.2	0.4	1.8	1.9	-0.4	-0.8	2.3	1.5	1.8	0.8	0.3
Medication: Gliclazide	1.2	1.3	3.1	-0.9	-1.3	-1.5	0.5	0.8	-1.4	-1.8	-1.3	-0.8	-0.6
Guilty feelings	1.2	1.8	3.6	-1.8	-1.4	-1.5	0.7	1.5	-1.9	-1.4	-1.1	-0.8	-0.5
Alzheimer’s Disease (in mother)	1.1	1.3	2.8	0.3	1.2	1.7	-1.0	-1.4	1.5	1.4	1.2	0.3	0.3
Respiratory disease	1.1	2.5	5.8	-1.0	1.9	1.9	-1.0	-0.2	2.4	2.1	2.2	0.1	-0.1
Fed-up feelings	1.1	1.9	4.9	-2.2	0.0	0.0	-1.3	-1.4	-0.8	-0.2	-0.9	2.2	2.2
Qualifications: None of the above	1.1	2.5	5.8	-1.2	1.2	1.7	-2.4	-1.6	1.1	1.9	0.6	1.7	1.5
Mouth/teeth dental problems	1.1	1.6	3.7	-0.7	1.7	1.6	-0.7	-0.4	1.9	1.8	1.5	0.9	0.2
Medication: Ramipril	1.1	1.5	6.7	2.6	0.9	1.0	-1.2	-1.3	0.9	1.3	0.6	0.1	0.6
Breastfed as a baby	1.1	1.3	3.9	0.5	0.2	0.3	1.1	1.5	0.5	0.5	1.2	-2.0	-2.0
Illnesses of siblings: Diabetes	1.1	1.3	3.0	-0.4	1.7	1.4	0.5	0.5	1.4	1.5	1.7	0.5	0.2
Number of self-reported non-cancer illnesses	1.1	1.8	5.2	-2.3	0.6	0.8	-1.6	-1.6	0.5	0.8	-0.1	1.9	1.6
Neuroticism (Nagel 2018)	1.0	2.3	19.9	-4.5	0.5	0.0	0.6	1.1	-0.6	0.2	0.8	-0.1	-0.0
Mean Putamen Volume	1.0	1.2	2.6	-1.0	-0.2	-0.4	-1.3	-1.5	-0.8	-0.4	-1.0	1.6	1.4
Nervous feelings	1.0	1.9	7.8	-2.8	-0.4	-1.1	1.6	1.8	-1.1	-0.4	-0.0	-1.3	-1.0
Length of working week for main job	1.0	1.1	7.8	2.8	0.1	-0.0	0.7	1.2	0.2	-0.1	0.2	-0.8	-0.7
Peak expiratory flow (PEF)	1.0	2.2	5.3	-0.5	2.3	2.1	0.3	-0.2	2.2	1.6	2.1	0.3	0.5
Exposure to tobacco smoke outside home	1.0	1.3	3.7	-0.5	-0.4	-0.2	1.4	1.9	-0.1	-0.2	0.5	-1.8	-1.9
Migraine (self-reported)	1.0	1.2	5.2	2.3	-0.5	0.2	0.2	0.4	0.4	0.6	0.6	-1.7	-1.6
Pain experienced in last month	1.0	1.6	4.8	-0.2	0.4	0.5	1.4	1.6	0.7	1.0	1.4	-1.8	-2.2
Smoking Status	0.9	2.2	4.9	0.5	1.9	1.7	1.4	1.8	1.3	1.3	2.2	-1.4	-0.6
Sensitivity / hurt feelings	0.9	1.5	2.3	-1.3	-1.4	-1.3	0.9	1.2	-1.5	-0.7	-0.9	-1.5	-1.1
High blood pressure (mother)	0.9	1.3	2.1	-1.5	-0.9	-0.8	-0.9	-1.2	-1.4	-0.7	-1.4	1.0	1.1
Medication: Simvastatin	0.9	1.3	3.1	-0.5	0.9	1.1	-1.5	-1.3	0.4	1.2	0.2	1.3	1.8
Falls in the last year	0.9	1.2	2.8	-0.1	1.4	1.7	-0.6	-0.4	1.6	1.4	1.2	0.0	0.5
Body fat percentage	0.9	3.5	10.0	-0.7	0.5	0.8	-3.2	-2.7	0.6	0.7	-1.0	2.7	2.8
Knee pain experienced in last month	0.9	1.5	3.3	0.4	-1.2	-1.0	-0.7	-1.2	-1.4	-1.4	-1.8	1.0	1.3
Smoking status: Current	0.9	1.4	4.4	0.8	0.4	0.3	1.6	1.8	0.5	0.1	1.1	-2.1	-1.4
Ever taken oral contraceptive pill	0.9	1.0	4.1	2.0	-0.6	-0.3	-0.5	-1.1	-0.7	-1.0	-1.1	0.6	1.1
Medication: Blood pressure	0.9	1.6	5.0	-2.2	0.7	0.8	-1.4	-1.5	0.4	0.7	-0.0	1.5	1.6
Pain type(s) experienced in last month: Hip pain	0.9	1.1	2.5	0.6	1.6	1.3	0.6	0.7	1.5	1.1	1.6	-0.1	0.1
Alcohol drinker status: Never	0.9	1.0	2.8	-1.3	-1.7	-1.3	0.1	-0.0	-1.3	-0.6	-1.2	-0.4	-0.8
Average weekly beer plus cider intake	0.9	1.3	5.8	2.4	0.5	0.4	1.2	1.2	0.5	0.4	1.2	-1.1	-1.1
Commuting to job workplace: Cycle	0.9	1.1	2.0	-1.1	0.9	0.7	1.0	1.4	0.8	0.3	1.3	-1.4	-0.9
Bipolar Disorder (2018)	0.8	1.3	4.0	1.6	-0.1	-0.5	1.8	2.0	-0.3	-0.1	0.2	-1.1	-1.2
Frequency of depressed mood in last 2 weeks	0.8	1.1	3.0	-1.7	0.4	0.3	1.0	1.7	-0.1	0.6	1.0	-1.3	-0.8
Trunk fat percentage	0.8	3.2	9.0	-0.8	0.1	0.5	-3.0	-2.6	0.2	0.4	-1.3	2.6	2.5
Supplements: Glucosamine	0.8	1.1	6.7	-2.6	-0.2	-0.2	-0.3	-0.6	-0.7	-0.4	-0.4	1.2	1.0
Worrier / anxious feelings	0.8	1.5	7.1	-2.7	-0.5	-1.0	-0.2	0.4	-1.3	-1.1	-0.9	1.1	1.0
Ever highly irritable/argumentative for 2 days	0.8	1.0	2.7	-0.3	-0.6	-0.6	1.4	1.3	-0.4	-0.8	0.1	-1.6	-1.4
Number of full brothers	0.8	1.0	2.7	1.6	-0.8	-0.7	1.3	0.9	-0.7	-0.6	-0.2	-1.3	-1.0
Shortness of breath walking on level ground	0.8	0.9	2.5	-1.4	0.5	0.8	-0.8	-0.8	0.2	0.5	0.0	1.6	1.4
Qualifications: College or University degree	0.8	2.5	4.6	-0.2	1.2	0.9	1.8	2.0	1.6	1.2	2.1	-1.9	-2.0
Medication: Ibuprofen	0.8	1.0	3.3	1.8	-0.6	-0.7	0.3	0.9	-0.1	-0.6	-0.1	-1.6	-1.3
Medication: Omeprazole	0.8	0.9	2.3	-1.5	-0.4	-0.3	-0.8	-0.9	-1.0	-0.9	-1.0	1.1	1.2
Suffer from ‘nerves’	0.8	1.3	2.5	-1.6	-1.0	-1.2	0.6	1.2	-1.4	-1.1	-0.5	-1.3	-1.2
Eye problems/disorders: Glaucoma	0.8	1.0	2.6	0.4	-1.6	-1.3	0.6	-0.2	-1.1	-0.9	-1.4	-0.8	-0.8
Number of operations (self-reported)	0.8	1.2	8.2	-2.9	-0.5	-0.3	-1.4	-1.0	-0.4	-0.1	-0.6	0.5	0.3
Age at First Birth	0.7	1.0	3.1	0.7	-0.2	0.3	-1.5	-1.8	-0.0	-0.2	-0.6	1.3	1.3
Body Mass Index (BMI) (2010)	0.7	0.9	2.2	-0.5	1.1	1.2	-0.9	-1.0	1.5	1.0	1.0	0.3	-0.0
Neuroticism (2016)	0.7	1.0	2.8	-1.3	-0.1	-0.3	1.1	1.7	-0.4	-0.1	0.4	-1.6	-1.3
Supplements: Zinc	0.7	0.7	1.8	-1.4	0.9	0.9	0.3	0.6	1.0	0.5	1.2	-0.5	-0.2
Heel bone mineral density (BMD) T-score, automated (left)	0.7	1.6	4.1	0.9	-1.6	-1.6	-1.1	-0.9	-1.2	-1.5	-2.0	0.4	0.5
Medication: Atenolol	0.7	0.9	1.7	-0.1	0.9	0.9	-0.7	-1.3	1.0	1.1	0.4	1.2	1.2
Number of incorrect matches in round	0.7	1.1	1.9	0.0	-1.2	-1.4	0.6	0.8	-1.4	-1.4	-1.0	-1.1	-0.9
Had menopause	0.7	0.9	2.5	-1.2	0.7	0.7	-1.1	-1.1	0.4	0.2	0.2	1.6	1.3
Neuroticism score	0.7	1.4	6.6	-2.6	-0.7	-1.0	0.8	1.4	-1.3	-0.8	-0.5	-0.7	-0.5
Medication: Ibuprofen (e.g. Nurofen)	0.7	0.9	2.7	1.6	-0.9	-0.9	0.4	0.8	-0.6	-0.9	-0.4	-1.2	-1.1
Medication: Ventolin 100micrograms inhaler	0.7	1.0	1.9	-0.7	-1.4	-1.2	-0.0	0.5	-1.2	-0.7	-0.9	-1.1	-1.2
Emphysema/chronic bronchitis	0.7	0.8	3.3	-0.9	-0.4	-0.3	0.9	1.8	-0.4	-0.3	0.3	-1.2	-1.0
Illnesses of father: Heart disease	0.7	1.0	2.7	-0.5	1.3	1.4	-0.2	0.4	1.6	1.2	1.5	0.1	-0.0
Commuting to job workplace: Public transport	0.7	0.8	1.8	-0.7	-1.0	-1.3	0.9	0.4	-1.2	-1.2	-0.9	-0.6	-0.2
Deep venous thrombosis (DVT) (self-reported)	0.7	0.9	2.3	0.2	-1.3	-1.4	-0.1	0.5	-1.5	-1.2	-1.1	-0.5	-0.4
Schizophrenia vs Biploar Disorder	0.6	0.8	2.3	-1.5	0.6	0.7	-0.1	0.3	1.0	0.8	1.1	-1.0	-0.9
Rheumatoid Arthritis	0.6	0.8	2.1	-1.2	-1.1	-1.0	-0.8	-0.2	-0.9	-0.7	-1.4	0.6	0.1
Neuroticism	0.6	1.6	11.5	-3.4	0.1	-0.6	0.8	1.5	-0.8	-0.4	0.2	-0.4	-0.2
Relative age of first facial hair	0.6	1.3	3.2	-0.0	-1.1	-1.1	1.2	1.3	-0.8	-0.9	-0.2	-1.6	-1.8
Current tobacco smoking	0.6	1.0	2.6	1.3	0.5	0.5	1.0	1.2	0.6	0.4	1.0	-1.6	-1.1
Diverticular disease/diverticulitis (self-reported)	0.6	0.7	1.5	0.5	0.8	0.9	-0.8	-0.7	0.6	1.2	0.3	0.9	1.1
Trunk fat mass	0.6	2.7	7.0	-1.1	0.0	0.3	-2.7	-2.3	0.1	0.3	-1.2	2.3	2.4
Asthma	0.6	1.2	3.0	-0.6	0.9	1.3	-1.3	-0.4	1.5	1.7	1.3	-0.5	-0.6
Seen doctor (GP) for nerves, anxiety, tension or depression	0.6	1.0	6.1	-2.5	0.2	0.5	0.3	0.8	0.3	0.3	0.7	-1.1	-0.8
Blood clot in the leg (DVT)	0.6	0.7	1.9	0.3	-1.2	-1.2	-0.1	0.4	-1.4	-1.0	-1.0	-0.4	-0.3
Gout (self-reported)	0.6	0.8	2.0	-1.3	0.8	0.4	-0.5	-0.7	0.4	0.9	0.3	1.2	1.4
High blood pressure (siblings)	0.6	0.8	1.3	-0.8	1.0	1.0	-1.1	-0.6	0.8	1.1	0.6	1.1	0.7
Had major operations	0.6	0.7	1.6	-1.3	-1.0	-1.1	-0.6	-0.1	-0.9	-1.1	-1.0	0.1	0.1
Mood swings	0.6	1.2	8.9	-3.0	0.1	0.0	1.1	0.9	-0.5	0.0	0.2	-0.3	0.3
Osteoporosis (self-reported)	0.6	0.7	1.9	-0.8	0.9	1.0	-0.4	-0.0	1.4	1.2	1.1	0.3	0.0
Miserableness	0.6	1.0	3.8	-1.9	0.8	0.7	0.9	1.2	0.5	0.5	1.2	-0.7	-0.4
Unable to work because of sickness or disability	0.6	0.8	3.4	1.8	-0.3	-0.4	1.1	1.0	-0.6	-0.6	-0.1	-1.1	-0.1
Heart disease (siblings)	0.6	0.8	2.3	-0.6	-0.0	0.4	-1.4	-1.3	0.2	0.7	-0.5	1.5	0.7
Leg fat mass (left)	0.6	2.2	6.0	-0.7	0.5	0.5	-2.3	-2.1	0.5	0.6	-0.7	2.1	2.4
Major Depression (MDD)	0.5	0.6	1.4	-0.5	0.8	1.0	-1.2	-0.7	1.0	1.0	0.7	0.2	0.0
Allergy or Eczema	0.5	1.3	3.1	-1.2	1.5	1.3	-0.1	0.2	1.8	1.2	1.5	0.6	0.2
Ever used hormone-replacement therapy (HRT)	0.5	0.7	1.7	-0.7	-1.2	-1.0	-0.1	0.1	-1.3	-1.0	-1.2	0.1	-0.0
Impedance of leg (left)	0.5	2.6	4.8	-1.3	1.4	1.8	-2.2	-1.7	1.3	1.8	1.0	1.9	1.0
Illnesses of siblings	0.5	0.6	1.7	0.1	-1.0	-1.1	0.2	-0.1	-1.0	-1.3	-1.0	-0.7	-0.1
Whole body fat mass	0.5	2.3	6.3	-0.9	0.2	0.4	-2.5	-2.0	0.4	0.4	-1.0	2.1	2.3
Leg fat mass (right)	0.5	2.1	5.6	-0.9	0.5	0.5	-2.2	-2.0	0.6	0.6	-0.6	2.0	2.4
Average weekly red wine intake	0.5	0.7	2.8	0.3	0.7	0.5	-0.6	-0.9	0.5	0.4	0.2	1.4	1.7
Loneliness, isolation	0.5	0.6	1.3	0.7	-0.7	-0.6	0.7	1.0	-1.1	-0.9	-0.6	-0.9	-0.6
Ever had bowel cancer screening	0.5	0.6	1.9	-1.1	-0.1	-0.0	-1.1	-0.7	-0.3	-0.0	-0.5	1.4	0.7
Ever smoked	0.5	0.8	1.8	0.5	1.0	0.8	1.1	1.3	0.5	0.4	1.4	-1.0	-0.5
Irritability	0.5	0.9	3.4	-0.1	0.5	-0.1	1.8	1.8	0.1	-0.1	0.8	-1.0	-0.7
Fractured/broken bones in last 5 years	0.5	0.6	1.7	-0.2	1.2	0.9	0.2	-0.2	1.0	1.3	1.1	0.5	0.2
Medication: Omeprazole (e.g. Zanprol)	0.5	0.6	1.5	-1.2	-0.5	-0.4	-0.3	-0.4	-1.0	-1.0	-0.9	0.8	0.8
HDL Cholesterol	0.4	0.7	1.6	1.1	-0.9	-1.1	1.2	0.4	-1.2	-0.8	-0.7	-0.4	-0.2
BMI	0.4	2.6	5.3	0.0	1.7	1.7	-1.5	-1.7	1.9	1.5	0.6	1.7	2.3
Lung FVC	0.4	1.8	5.4	-0.6	0.9	0.5	2.3	1.3	0.7	-0.1	1.7	-2.0	-1.5
Chronotype (morning person)	0.4	0.9	2.4	-0.5	-0.9	-0.9	-1.5	-1.0	-0.6	-0.3	-1.3	1.2	0.4
Hearing difficulty/problems: Yes	0.4	0.7	2.6	-1.2	0.4	0.3	-0.1	-0.9	0.1	0.2	-0.0	1.3	1.6
Angina	0.4	0.6	1.7	-0.6	-1.1	-0.9	-0.1	-0.1	-1.0	-0.7	-1.3	-0.2	-0.2
Medication: Metformin	0.4	0.6	1.8	0.1	0.0	0.2	-1.0	-1.3	-0.2	-0.1	-0.5	1.0	1.2
Impedance of leg (right)	0.4	2.1	3.4	-1.8	1.3	1.7	-1.8	-1.4	1.3	1.6	1.0	1.5	0.7
Frequency of unenthusiasm / disinterest in last 2 weeks	0.4	0.5	2.0	-0.1	-0.1	-0.2	1.0	1.4	-0.8	-0.6	0.2	-0.8	-0.5
Taking other prescription medications	0.4	0.7	2.0	-1.4	-0.0	-0.3	-0.6	-0.7	-0.5	-0.3	-0.7	1.1	1.2
Chronic bronchitis/emphysema (father)	0.4	0.5	1.2	-0.1	0.6	0.7	-0.9	-1.1	0.4	0.1	0.2	1.0	0.9
Body mass index (BMI)	0.4	1.6	5.0	0.3	0.3	0.4	-1.9	-1.9	0.5	0.4	-0.7	1.7	2.2
Past tobacco smoking	0.4	0.7	1.6	-0.3	-1.3	-1.1	-0.5	-1.0	-0.5	-0.6	-1.3	0.6	0.2
Hair/balding pattern: Pattern 2	0.4	0.5	2.0	-1.4	0.7	0.6	-0.8	-0.2	0.4	0.4	0.5	1.0	0.4
Diabetes (self-reported)	0.4	0.6	1.5	-0.3	0.7	0.7	-0.9	-1.1	0.4	0.4	0.2	1.2	1.1
Father’s age at death	0.4	0.6	1.0	-1.0	0.5	0.6	0.3	0.6	0.8	0.9	1.0	-0.5	-0.8
Number of live births	0.4	0.6	1.0	-1.0	-0.8	-0.9	0.6	0.7	-0.9	-0.5	-0.6	-0.9	-0.7
Pulse rate	0.4	0.6	2.0	-1.0	-0.5	-0.4	0.7	1.4	-0.3	-0.2	0.1	-0.9	-1.1
Happiness	0.4	0.4	1.4	1.2	0.6	0.7	0.8	0.5	0.5	0.3	0.8	-0.4	-0.3
Medication: Lansoprazole	0.4	0.5	1.1	0.6	-0.9	-0.9	-0.4	0.0	-1.0	-0.8	-1.0	0.4	0.2
Headache pain in last month	0.4	0.6	1.9	-0.3	0.9	1.1	-0.2	0.2	1.4	1.0	1.1	0.0	0.1
Worry too long after embarrassment	0.4	0.6	2.2	-1.5	-0.8	-0.9	-0.4	0.2	-1.1	-0.5	-0.9	0.1	0.3
Heart disease (mother)	0.4	0.5	1.1	-0.3	1.0	0.9	-0.6	-0.1	1.0	0.8	0.8	0.6	0.5
Number of full sisters	0.4	0.5	1.0	0.5	0.6	0.5	0.5	0.7	0.8	0.8	1.0	-0.8	-0.4
Chest pain or discomfort	0.4	0.5	2.0	-0.5	0.0	-0.4	0.7	1.4	0.5	-0.2	0.1	-1.1	-1.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.4	0.5	1.0	-1.0	-0.6	-0.5	-0.4	-0.7	-0.9	-0.8	-0.8	0.5	0.5
Arm fat percentage (left)	0.4	1.4	4.1	-0.2	0.1	0.4	-2.0	-1.7	0.3	0.4	-0.9	1.6	1.9
Ever had stillbirth, spontaneous miscarriage or termination	0.4	0.4	1.2	0.1	0.6	0.5	0.5	1.1	0.3	0.4	1.0	-0.9	-0.3
Breast cancer (self-reported)	0.4	0.4	2.5	-1.6	-0.2	-0.5	0.8	0.7	-0.2	-0.6	-0.1	-0.3	-0.3
Asthma (self-reported)	0.4	0.9	1.9	-0.5	0.8	1.0	-1.2	-0.3	1.3	1.4	1.1	-0.5	-0.5
Arm fat mass (left)	0.4	1.7	4.6	-0.7	0.2	0.4	-2.1	-1.8	0.4	0.5	-0.8	1.8	2.1
Illnesses of father: High blood pressure	0.4	0.5	1.1	1.0	0.8	0.8	0.3	0.6	0.8	0.9	1.0	-0.5	-0.3
Supplements: Calcium	0.4	0.4	0.9	0.1	0.4	0.5	0.8	0.7	0.5	0.8	0.9	-0.5	-0.7
HbA1C	0.3	0.3	1.0	-1.0	0.1	0.1	-0.9	-0.4	-0.1	0.3	-0.2	0.8	0.8
Blood Eosinophil Count	0.3	2.5	5.2	-1.0	-2.3	-2.2	0.4	0.9	-2.1	-1.5	-2.0	-1.0	-0.8
Heel T-Score	0.3	2.4	4.8	1.7	-2.1	-1.9	-0.3	-0.8	-1.8	-2.0	-2.2	-0.1	-0.1
Lung FEV1/FVC ratio	0.3	1.7	3.4	0.9	1.1	1.3	-1.9	-1.4	1.2	1.1	0.2	1.8	1.4
Other serious medical condition/disability diagnosed by doctor	0.3	0.4	2.9	1.7	-0.2	-0.0	0.0	0.4	0.0	-0.7	-0.0	-0.7	-0.6
Ever had hysterectomy (womb removed)	0.3	0.3	1.0	0.1	-0.5	-0.2	-1.0	-0.8	-0.5	0.0	-0.6	0.5	0.2
Medication for hormone replacement therapy	0.3	0.3	0.6	-0.2	-0.8	-0.6	0.3	0.3	-0.7	-0.8	-0.6	-0.6	-0.3
Diabetes (mother)	0.3	0.4	0.9	0.7	0.9	0.6	0.4	0.5	0.7	0.6	1.0	0.2	0.2
Leg fat-free mass (left)	0.3	1.3	2.6	-0.9	-1.2	-1.6	1.0	1.2	-1.2	-1.5	-1.1	-1.0	-0.3
Average weekly fortified wine intake	0.3	0.3	1.3	0.0	-0.9	-0.5	-0.7	-0.5	-0.4	0.0	-1.1	0.3	0.1
Relative age voice broke	0.3	0.4	1.7	1.3	-0.2	-0.1	0.7	0.5	-0.2	-0.0	0.3	-0.8	-1.0
Age when periods started (menarche)	0.3	0.8	4.4	2.1	-0.2	-0.1	0.8	0.9	-0.3	-0.2	0.2	-1.1	-0.9
Bilateral oophorectomy (both ovaries removed)	0.3	0.4	1.1	0.5	-1.0	-0.9	-0.4	-0.3	-0.7	-0.5	-1.0	-0.2	-0.2
Hayfever, allergic rhinitis or eczema	0.3	0.6	1.7	-1.2	0.8	0.7	-0.0	0.3	1.3	0.6	1.0	0.1	-0.3
Alcohol usually taken with meals	0.3	0.5	1.3	-0.3	-1.2	-1.0	0.0	0.1	-0.7	-0.9	-1.0	-0.4	-0.6
Had other major operations	0.3	0.4	2.7	-1.6	0.5	0.4	0.2	-0.2	0.4	0.3	0.5	0.3	0.2
Fluid intelligence score	0.3	0.6	1.6	-1.3	-0.6	-0.8	0.9	0.3	-0.6	-1.0	-0.4	-0.5	-0.3
Noisy workplace	0.3	0.4	1.1	0.3	0.1	0.6	-1.1	-0.8	0.2	0.6	-0.3	0.7	0.9
Depression (self-reported)	0.3	0.4	2.2	-1.5	0.6	0.5	0.1	0.1	0.2	0.7	0.7	0.2	0.6
Pulse wave Arterial Stiffness index	0.3	0.3	0.7	0.2	-0.8	-0.7	0.1	0.4	-0.5	-0.8	-0.5	-0.6	-0.8
Arm fat mass (right)	0.3	1.4	4.1	-0.7	0.0	0.2	-1.9	-1.6	0.2	0.2	-1.0	1.6	2.0
Pulse wave reflection index	0.3	0.4	1.0	0.7	0.5	0.5	-1.0	-0.8	0.7	0.3	0.3	0.6	0.5
Hypothyroidism/myxoedema (self-reported)	0.3	0.6	1.9	-0.2	-0.8	-1.1	0.3	-0.2	-0.9	-1.4	-0.9	-0.1	0.1
Age at first live birth	0.3	0.6	1.3	-1.1	-0.9	-0.8	0.6	0.4	-0.5	-0.6	-0.5	-1.0	-1.1
Health satisfaction	0.3	0.5	2.0	-0.3	0.2	-0.1	1.4	1.2	-0.2	-0.4	0.5	-0.6	-0.3
Angina (self-reported)	0.3	0.4	1.0	-0.9	-0.9	-0.7	-0.1	-0.1	-0.7	-0.4	-1.0	-0.3	-0.4
Medication: Seretide 50 evohaler	0.3	0.3	0.7	-0.6	0.7	0.4	-0.2	0.0	0.8	0.7	0.7	-0.3	-0.1
Comparative height size at age 10	0.3	1.6	12.1	-3.5	-0.5	-0.5	-0.6	-0.5	-0.6	-0.3	-0.8	0.9	0.5
Illness, injury, bereavement, stress in last 2 years	0.3	0.4	1.2	-0.1	1.1	0.6	0.0	0.4	0.7	1.0	1.0	0.3	-0.0
Smoking status: Previous	0.3	0.4	1.2	0.0	1.0	1.1	-0.7	-0.1	0.5	0.7	0.6	0.5	0.4
Leg fat-free mass (right)	0.3	1.4	3.0	-0.6	-1.3	-1.7	1.1	1.2	-1.3	-1.5	-1.2	-1.0	-0.3
Back pain experienced in last month	0.3	0.4	2.0	1.4	-0.1	-0.2	-0.4	-0.5	-0.1	-0.6	-0.5	0.4	0.9
Mineral and other dietary supplements	0.3	0.4	1.5	0.1	-0.3	-0.3	0.5	0.7	-0.6	-0.6	-0.1	-1.2	-0.7
Leg predicted mass (right)	0.3	1.5	3.1	-0.6	-1.4	-1.8	1.1	1.3	-1.3	-1.5	-1.2	-1.1	-0.3
Supplements: Fish oil (including cod liver oil)	0.3	0.4	1.4	0.3	-0.4	-0.4	-0.7	-0.9	-0.0	-0.3	-0.8	1.2	0.4
Heart attack/myocardial infarction (self-reported)	0.3	0.4	0.9	0.9	0.2	0.4	-1.0	-0.8	0.5	0.4	-0.3	0.8	0.7
Intelligence (Savage-Jansen 2018)	0.2	0.6	3.3	-1.8	0.3	0.3	0.5	0.0	0.9	0.6	0.6	-0.6	-0.7
Lupus	0.2	0.3	0.9	0.9	-0.4	-0.5	-0.1	0.5	-0.2	-0.9	-0.4	-0.1	-0.3
Type 2 Diabetes (T2D) (2012)	0.2	0.2	0.5	-0.4	-0.7	-0.5	-0.2	-0.1	-0.5	-0.7	-0.6	0.3	-0.0
Blood Platelet Count	0.2	2.2	5.6	0.4	-2.1	-1.6	-0.7	-1.1	-2.0	-1.7	-2.4	0.5	0.4
Waist Hip Ratio (WHR)	0.2	0.8	1.4	0.8	-1.0	-0.6	0.9	1.2	-1.0	-0.7	-0.4	-1.0	-0.9
Hand grip strength (left)	0.2	0.6	1.6	1.3	0.9	0.7	-0.5	-1.0	0.9	0.4	0.6	0.1	0.3
Number of treatments/medications taken	0.2	0.4	1.0	-1.0	0.4	0.2	-0.9	-0.7	0.0	0.1	-0.3	1.0	1.0
Eye problems/disorders: Diabetes related eye disease	0.2	0.2	1.0	-0.7	0.1	0.2	-0.3	0.1	0.2	1.0	0.2	0.4	-0.1
Qualifications: CSEs or equivalent	0.2	0.3	2.6	1.6	-0.2	-0.1	0.3	0.0	0.1	0.2	-0.1	-0.6	-0.4
Stomach or abdominal pain in last month	0.2	0.2	0.8	0.5	0.0	-0.3	0.3	0.9	-0.2	-0.8	-0.2	-0.1	-0.3
Leg predicted mass (left)	0.2	1.3	2.6	-0.8	-1.2	-1.6	1.0	1.2	-1.1	-1.4	-1.1	-1.0	-0.3
Forced vital capacity (FVC)	0.2	0.8	2.5	-1.6	0.4	0.3	1.3	0.5	0.5	-0.1	0.8	-1.2	-0.9
Heart attack	0.2	0.2	1.0	1.0	0.2	0.3	-0.5	-0.4	0.5	0.3	-0.1	0.3	0.2
Weight	0.2	1.0	2.8	-0.9	-0.3	-0.3	-1.4	-1.2	-0.1	-0.1	-1.1	1.2	1.7
Impedance of arm (right)	0.2	0.8	2.6	-1.4	-0.8	-0.3	0.5	1.1	-0.5	-0.3	-0.0	-1.2	-1.6
Arm fat percentage (right)	0.2	1.0	2.9	-0.3	-0.1	0.2	-1.7	-1.4	0.1	0.2	-0.9	1.2	1.6
Hip circumference	0.2	0.8	1.9	-1.3	-0.1	-0.1	-1.4	-1.0	0.2	-0.1	-0.9	0.8	1.2
Time employed in main current job	0.2	0.3	0.9	-0.9	-0.4	-0.5	0.1	0.5	-0.3	-0.5	-0.3	-0.3	-0.7
Hair/balding pattern: Pattern 3	0.2	0.3	0.8	0.7	0.2	0.5	-0.3	0.1	0.9	0.7	0.5	-0.9	-0.6
Forced expiratory volume in 1-second (FEV1)	0.2	0.6	2.1	-1.5	0.6	0.5	1.1	0.4	0.7	0.1	0.9	-0.8	-0.6
Prospective memory result	0.2	0.2	0.8	0.4	0.4	0.5	0.2	-0.3	-0.2	0.1	0.2	0.8	0.9
Lung cancer (father)	0.2	0.2	0.4	0.3	-0.2	-0.4	-0.2	-0.4	-0.6	-0.3	-0.7	0.5	0.6
Standing height	0.2	1.7	6.0	-2.5	-1.1	-1.3	1.0	1.4	-1.0	-1.1	-0.7	-1.0	-1.1
Loud music exposure frequency	0.2	0.2	0.4	0.6	0.5	0.4	0.4	0.5	0.3	0.0	0.6	-0.7	-0.2
Medication: Paracetamol	0.2	0.4	0.8	-0.5	-0.4	-0.3	-0.9	-0.5	-0.6	-0.4	-0.8	0.5	0.9
Medication: Amlodipine	0.2	0.3	1.0	-0.2	1.0	0.6	0.5	0.4	0.7	-0.0	0.7	0.5	0.0
Birth weight	0.2	0.4	1.1	-0.2	0.9	0.7	-0.5	0.1	1.0	1.1	0.9	0.2	0.2
Chronic bronchitis/emphysema (mother)	0.2	0.2	0.7	-0.7	0.5	0.2	0.2	0.8	0.3	0.5	0.8	-0.1	-0.3
Wheeze or whistling in the chest in last year	0.2	0.4	0.7	-0.7	0.8	0.8	-0.2	0.4	0.8	0.8	0.9	-0.3	-0.1
Pulse wave peak to peak time	0.2	0.2	0.5	-0.3	0.7	0.6	0.1	-0.2	0.4	0.7	0.5	0.3	0.6
Medication for pain relief, constipation, heartburn	0.2	0.4	1.1	-0.7	0.7	0.5	0.2	0.3	0.8	0.9	1.0	0.0	-0.4
Neck or shoulder pain in last month	0.2	0.3	0.6	-0.7	-0.0	0.1	-0.7	-0.5	-0.3	-0.4	-0.5	0.8	0.7
Pulse rate, automated reading	0.2	0.7	4.1	-2.0	-0.3	-0.3	0.5	0.9	-0.2	-0.3	0.0	-0.8	-0.8
Leg pain on walking	0.2	0.3	0.7	0.8	-0.2	0.0	-0.7	-0.7	-0.1	-0.5	-0.4	0.3	0.6
Commuting to job workplace: Car/motor vehicle	0.2	0.2	0.8	-0.2	-0.6	-0.5	-0.6	-0.4	-0.3	-0.4	-0.9	0.4	0.2
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.3	1.0	-0.4	-1.0	-0.6	-0.0	0.2	-0.7	-0.5	-0.8	-0.5	-0.4
Diabetes diagnosed by doctor	0.2	0.3	1.3	-1.2	0.5	0.6	-0.4	-0.2	0.2	0.4	0.3	0.5	0.7
Osteoarthritis (self-reported)	0.2	0.2	0.5	-0.3	0.4	-0.2	0.6	0.5	-0.4	-0.5	0.0	0.7	0.7
Medication: Aspirin	0.2	0.2	0.6	0.8	0.5	0.6	-0.3	-0.2	0.5	0.5	0.3	-0.3	-0.0
Alzheimer’s Disease (including proxy)	0.1	0.2	0.9	0.1	-0.6	-0.2	-0.1	-0.3	-0.0	-0.1	-0.0	-0.9	-1.0
Verbal and Numeric Reasoning (VNR)	0.1	0.3	1.5	-1.2	0.1	0.3	0.4	-0.1	0.6	0.0	0.3	-0.5	-0.6
Triglycerides	0.1	0.2	1.3	-1.1	0.2	0.3	-0.5	-0.1	0.3	0.3	0.1	0.2	-0.0
Blood Red Count	0.1	1.2	3.5	1.3	0.8	1.1	-1.3	-0.4	1.9	1.2	1.1	-0.3	-0.7
Height	0.1	2.4	7.2	-1.5	-1.2	-1.0	1.5	2.0	-0.5	-0.6	-0.1	-2.2	-2.7
Hypothyroidism (self reported)	0.1	0.2	0.6	-0.2	-0.2	-0.6	0.4	-0.1	-0.6	-0.8	-0.5	-0.3	0.2
Type 2 Diabetes (T2D) (2018)	0.1	0.1	0.4	0.6	0.4	0.3	0.4	0.4	0.4	0.1	0.4	-0.1	-0.1
Tanning	0.1	1.1	3.9	-2.0	0.3	0.5	-1.6	-1.4	0.4	0.1	-0.1	1.0	0.8
Medication: Co-codamol	0.1	0.1	0.3	-0.2	0.4	0.3	0.5	0.3	-0.1	-0.2	0.1	0.0	0.5
Pack years adult smoking proportion	0.1	0.1	0.4	0.2	-0.2	-0.2	-0.2	0.6	-0.5	-0.3	-0.3	-0.1	0.2
Hand grip strength (right)	0.1	0.3	0.8	0.5	0.8	0.5	-0.1	-0.5	0.9	0.5	0.7	0.2	0.1
Sitting height	0.1	0.5	2.6	-1.6	0.4	0.4	-0.6	-0.6	0.4	0.2	0.1	0.7	0.7
Waist circumference	0.1	0.4	1.2	-0.3	-0.4	-0.2	-0.8	-0.6	-0.3	-0.3	-1.0	0.7	1.1
Allergy	0.1	0.3	1.5	1.2	-0.1	-0.2	0.4	-0.4	-0.6	-0.4	-0.5	0.3	0.6
Trunk fat-free mass	0.1	0.4	1.8	-1.3	-0.5	-0.8	0.4	0.5	-0.3	-0.6	-0.5	-0.5	0.1
Frequency of tiredness / lethargy in last 2 weeks	0.1	0.2	0.6	-0.8	0.7	0.5	0.2	0.3	0.2	0.2	0.5	0.2	0.5
Serious illness, injury or assault of a close relative in last 2 years	0.1	0.2	0.6	-0.4	-0.1	0.0	-0.3	-0.8	0.2	0.0	-0.5	0.3	0.6
Illnesses of mother	0.1	0.2	0.4	0.0	0.1	0.1	-0.4	-0.6	0.2	0.5	-0.3	0.6	0.6
Forced expiratory volume in 1-second (FEV1), Best measure	0.1	0.2	0.6	-0.7	0.5	0.5	0.8	-0.2	0.6	0.2	0.5	-0.4	-0.1
Impedance of arm (left)	0.1	0.3	1.0	-0.9	-0.5	-0.1	0.1	0.5	-0.2	-0.2	-0.0	-0.4	-1.0
Trunk predicted mass	0.1	0.4	1.6	-1.3	-0.5	-0.8	0.6	0.7	-0.3	-0.6	-0.4	-0.7	-0.1
Hair/balding pattern: Pattern 4	0.1	0.3	1.1	0.2	0.6	0.3	0.2	-0.7	0.2	0.2	0.2	1.0	1.1
Forced vital capacity (FVC), Best measure	0.1	0.5	1.1	-1.0	0.4	0.4	1.0	0.1	0.7	0.3	0.8	-0.8	-0.5
Comparative body size at age 10	0.1	0.2	1.2	0.2	0.3	-0.2	1.1	0.4	0.3	-0.0	0.4	-0.5	-0.3
Reason for reducing amount of alcohol drunk: Health precaution	0.1	0.1	0.3	0.0	0.1	-0.0	0.5	0.4	0.2	0.1	0.2	-0.5	-0.3
Medication: Allopurinol	0.1	0.2	0.5	-0.3	0.6	0.3	0.2	-0.1	0.3	0.7	0.4	0.2	0.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.1	0.1	0.5	-0.1	0.1	-0.2	0.2	0.3	-0.1	-0.7	0.3	0.2	-0.4
Overall health rating	0.1	0.2	1.0	-0.3	0.6	0.4	-0.0	0.3	0.1	0.1	0.3	0.7	1.0
Qualifications: NVQ or HND or HNC or equivalent	0.1	0.1	0.4	0.3	0.1	-0.2	0.6	0.2	-0.5	-0.6	-0.1	0.2	0.5
Medication: Aspirin	0.1	0.2	0.8	0.9	0.5	0.5	-0.0	-0.2	0.4	0.5	0.3	-0.2	0.1
Supplements: Vitamin C	0.1	0.1	0.3	-0.3	0.6	0.1	-0.0	-0.0	0.2	0.1	0.3	0.3	0.3
Whole body fat-free mass	0.1	0.7	1.5	-1.1	-0.9	-1.2	0.6	0.7	-0.8	-1.0	-0.8	-0.7	0.0
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.1	0.2	0.7	-0.9	0.3	0.4	-0.2	-0.4	0.5	0.3	0.2	-0.1	-0.3
Whole body water mass	0.1	0.6	1.3	-0.9	-0.8	-1.1	0.6	0.7	-0.7	-0.9	-0.8	-0.6	0.0
Average weekly champagne plus white wine intake	0.1	0.2	1.1	-1.1	0.1	0.2	0.2	0.1	0.5	0.3	0.4	-0.3	-0.4
Hearing aid user	0.1	0.1	0.3	0.4	0.3	0.5	-0.1	-0.2	0.3	0.5	0.3	0.3	0.1
Medication: Paracetamol	0.1	0.2	0.5	-0.1	-0.5	-0.4	-0.7	-0.1	-0.6	-0.5	-0.7	0.2	0.5
Basal metabolic rate	0.1	0.5	1.1	-1.0	-0.7	-1.0	0.2	0.3	-0.6	-0.8	-0.9	-0.2	0.4
Arm fat-free mass (left)	0.1	0.4	1.3	-1.1	-0.2	-0.4	-0.6	-0.5	-0.2	-0.3	-0.7	0.6	1.2
Pack years of smoking	0.1	0.1	0.3	0.3	-0.0	-0.2	-0.5	0.3	-0.4	-0.3	-0.3	0.3	0.5
Impedance of whole body	0.1	0.6	1.7	-1.1	0.3	0.8	-1.3	-0.9	0.3	0.7	0.2	1.0	0.3
Arm predicted mass (left)	0.1	0.3	1.2	-1.1	0.0	-0.3	-0.4	-0.4	-0.0	-0.1	-0.4	0.4	0.9
Breast Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Prostate Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Hair Pigment	0.0	0.5	1.0	-0.9	-0.7	-0.9	0.2	0.5	-1.0	-1.0	-0.8	-0.3	-0.1
Tinnitus: Yes, but not now, but have in the past	0.0	0.0	0.1	0.0	-0.3	-0.1	-0.1	-0.3	-0.1	-0.2	-0.3	-0.2	0.1
Medication: Levothyroxine sodium	0.0	0.0	0.0	-0.0	0.2	-0.2	0.1	-0.2	0.1	-0.2	0.2	-0.1	0.0
Arm fat-free mass (right)	0.0	0.2	1.0	-0.4	-0.0	-0.4	-0.5	-0.4	-0.1	-0.2	-0.5	0.5	1.0
Arm predicted mass (right)	0.0	0.2	0.9	-0.3	0.1	-0.3	-0.4	-0.2	0.0	-0.1	-0.4	0.5	0.9

Hub : Genes

PRKAB1

Models

Trait associations