Hub : Genes

PSME4

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0680	0.0280	2.6e-03	0.034	0.017	0.037	0.032	0.038	4.8e-05	3.5e-03	2.0e-05	8.3e-05	1.7e-05
2	GTEx	Lung	0.0932	0.0323	3.0e-05	0.084	NA	0.064	NA	0.083	5.2e-07	NA	1.3e-05	NA	6.0e-07
3	GTEx	Skin Not Sun Exposed Suprapubic	0.1120	0.0490	1.9e-03	0.005	NA	0.000	NA	0.007	1.7e-01	NA	3.1e-01	NA	1.2e-01
4	GTEx	Skin Sun Exposed Lower leg	0.1010	0.0380	1.4e-03	0.039	NA	0.020	NA	0.042	3.5e-04	NA	8.1e-03	NA	2.1e-04
5	ROSMAP	Brain Pre-frontal Cortex	0.0726	0.0210	5.1e-09	0.079	0.070	0.086	0.072	0.073	2.4e-10	2.4e-09	3.9e-11	1.3e-09	1.0e-09
6	YFS	Blood	0.0352	0.0098	3.7e-09	0.023	0.028	0.035	0.030	0.032	3.6e-08	1.1e-09	1.1e-11	2.5e-10	8.1e-11
7	TCGA	Bladder Urothelial Carcinoma	0.0500	0.0300	1.7e-03	0.018	0.019	0.008	NA	0.015	1.1e-02	8.9e-03	6.1e-02	NA	1.7e-02
8	TCGA	Glioblastoma Multiforme	0.1380	0.0850	9.7e-03	0.142	0.056	0.085	NA	0.120	4.4e-05	8.7e-03	1.5e-03	NA	1.7e-04
9	TCGA	Brain Lower Grade Glioma	0.0379	0.0220	9.0e-03	0.026	0.018	0.010	NA	0.019	5.6e-04	3.4e-03	2.5e-02	NA	2.5e-03

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Bipolar Disorder (2018)	0.8	1.3	6.2	0.5	-0.2	1.0	0.4	1.2	-1.7	0.2	0.1	2.5
Bipolar Disorder or Schizophrenia	1.7	4.1	11.0	0.4	1.3	0.3	0.1	2.8	-3.3	-1.7	2.6	2.6
Depressed Affect (Nagel 2018)	1.4	3.0	4.8	2.2	-1.4	1.9	2.1	-0.1	-0.8	1.6	-2.2	1.9
Depression (Nagel 2018)	2.6	4.0	8.4	2.4	-1.7	2.9	2.3	-0.7	-0.9	2.0	-2.2	1.8
Intelligence (Savage-Jansen 2018)	3.0	9.1	20.7	1.8	3.3	-3.2	0.7	3.9	-2.4	-4.6	3.7	-0.9
Neuroticism (Nagel 2018)	1.2	2.8	7.5	2.7	0.5	1.2	2.2	1.4	-2.3	0.3	-0.2	2.0
Schizophrenia (2018)	2.0	4.2	10.9	0.1	1.9	-0.5	-0.2	2.6	-2.9	-2.4	3.3	1.4
Schizophrenia vs Biploar Disorder	1.6	2.1	4.9	1.1	1.3	-0.3	1.3	1.6	-2.2	-1.7	1.9	0.8
Worry (Nagel 2018)	0.8	1.8	3.8	1.9	1.6	-0.3	1.2	1.7	-2.0	-0.9	1.0	-0.2
Alzheimer’s Disease (in mother)	0.8	0.9	3.8	-0.6	0.3	0.2	-0.2	1.1	-2.0	-0.5	0.2	1.4
Alzheimer’s Disease (in father)	0.7	0.8	2.2	-1.0	-0.4	0.9	-0.3	-0.6	-0.1	0.9	1.3	1.5
Alzheimer’s Disease (including proxy)	0.7	1.1	2.9	-1.0	0.2	0.1	-0.3	0.9	-1.5	-0.5	1.5	1.7
Crohns Disease (2017)	1.6	3.5	8.7	2.3	-0.7	1.3	3.0	1.7	-2.3	-0.6	0.8	2.4
Irritable Bowel Disease (IBD)	0.4	0.8	3.1	1.1	-1.0	0.8	1.8	0.7	-0.5	-0.2	0.4	0.8
Ulcerative Colitis (UC)	0.2	0.3	1.2	0.1	-0.6	-0.1	0.3	-0.2	1.0	-0.0	0.0	-1.1
Major Depression (MDD)	0.3	0.3	0.6	0.8	-0.8	0.6	0.7	-0.2	-0.6	0.4	-0.4	0.4
Reaction Time	0.5	1.0	3.2	-0.6	0.4	1.0	-1.2	-1.4	0.6	1.8	-0.7	-0.1
Verbal and Numeric Reasoning (VNR)	4.3	10.3	19.0	2.3	3.6	-3.0	1.2	4.4	-2.8	-4.2	4.3	-0.7
Breast Cancer	0.2	0.4	1.2	-0.8	-0.2	0.3	-1.1	-0.6	0.7	0.7	-0.5	-0.3
Ovarian Cancer	0.6	0.8	1.9	1.0	-0.7	1.4	0.9	-0.3	-0.3	1.3	-0.1	1.2
Prostate Cancer	0.6	0.9	2.8	1.7	-0.7	0.8	1.1	0.4	-1.1	0.2	-0.7	0.9
Age at First Birth	0.6	0.8	2.1	-1.1	0.7	-1.4	-0.6	0.9	-0.6	-1.3	0.5	0.4
Bipolar Disorder (2011)	0.7	0.7	1.5	1.0	-0.0	0.5	1.0	1.0	-0.9	0.2	1.0	1.2
Body Mass Index (BMI) (2010)	1.6	2.2	6.1	0.3	2.0	-2.5	-0.8	1.8	-0.5	-1.7	1.1	-1.2
Coronary Artery Disease (CAD)	0.5	0.6	1.5	-1.0	-0.0	-0.9	-0.9	0.1	1.2	0.1	-0.4	-0.9
Crohns Disease (2012)	1.3	2.0	7.5	2.0	-1.1	1.4	2.7	0.5	-1.2	-0.2	0.7	1.2
Mean Putamen Volume	0.2	0.3	0.8	-0.5	-0.3	-0.4	-0.6	-0.9	0.5	0.2	-0.5	-0.6
Fasting Glucose	2.2	2.6	6.9	-0.5	-0.6	-0.0	-0.5	-2.6	2.2	1.9	-2.0	-1.7
HbA1C	0.5	0.5	0.9	1.0	0.8	-0.8	0.1	0.9	-0.2	-1.0	0.6	-0.6
HDL Cholesterol	1.1	1.9	4.6	-0.3	-2.0	2.1	0.9	-2.1	1.0	1.3	-0.6	-0.3
LDL Cholesterol	0.7	1.1	2.4	1.5	-1.5	1.4	1.5	-0.7	-0.0	0.3	-0.9	0.5
Lupus	0.3	0.5	1.3	1.0	-1.1	0.5	0.9	0.5	-0.8	-0.2	0.6	0.4
Neuroticism (2016)	1.6	2.4	6.5	1.0	1.8	0.5	0.5	1.9	-2.5	-0.8	1.5	1.9
Primary Biliary Cirrhosis	0.5	0.8	4.0	0.2	-2.0	0.6	0.5	-1.0	0.8	0.3	-0.5	0.2
Rheumatoid Arthritis	1.3	1.7	4.4	-0.7	-1.3	1.6	0.4	-1.4	0.1	1.6	-2.1	1.4
Schizophrenia (2014)	3.9	8.6	21.7	1.1	2.4	-0.9	0.8	3.8	-4.0	-3.5	4.7	2.1
Triglycerides	1.0	1.6	3.9	1.3	0.9	-1.0	0.4	2.0	-1.7	-1.4	0.8	1.1
Type 2 Diabetes (T2D) (2012)	0.4	0.4	0.9	-0.3	0.8	-0.5	-0.9	0.4	0.7	-0.1	-0.6	-0.9
Ulcerative Colitis	0.2	0.3	1.0	-0.3	-0.3	-0.4	-0.3	-0.0	1.0	-0.5	0.4	-0.7
Blood Eosinophil Count	1.0	7.9	19.1	0.9	2.7	-2.7	0.3	3.7	-3.4	-4.4	3.4	1.1
Blood Platelet Count	0.1	1.1	4.2	-1.2	-0.4	0.8	-0.6	0.0	-1.7	0.3	0.6	2.0
Blood Red Count	0.5	4.8	15.4	-1.4	-0.7	-0.6	-1.4	-2.8	3.9	0.7	-1.2	-3.7
Blood White Count	0.2	1.3	5.8	0.2	-0.2	0.7	0.7	1.0	-2.4	-0.3	-0.4	2.0
Heel T-Score	5.1	40.3	110.2	-9.4	1.9	-1.3	-10.5	-5.1	8.5	5.2	-5.0	-2.7
BMI	0.6	3.6	10.4	2.6	2.7	-0.7	1.1	3.2	-2.1	-0.7	0.9	0.2
Height	1.0	20.2	51.6	4.2	3.2	-3.1	2.4	7.2	-6.3	-6.2	1.9	2.5
Waist Hip Ratio (WHR)	0.1	0.2	0.8	-0.2	-0.9	0.1	-0.3	-0.2	-0.8	-0.4	-0.3	0.6
Systolic Blood Pressure	0.7	3.7	10.6	-0.2	-2.5	3.3	1.1	-1.1	-0.6	2.0	-0.9	3.0
Smoking Status	2.5	6.0	14.7	2.7	1.4	1.2	2.6	2.6	-3.5	-0.4	1.6	3.8
Allergy or Eczema	0.8	2.1	3.1	-1.1	1.4	-0.9	-1.3	1.5	-1.8	-1.6	1.8	1.5
Cardiovascular Disease	1.3	4.3	9.4	2.8	-1.1	2.1	3.1	1.3	-2.7	0.3	-0.4	2.5
Hypothyroidism (self reported)	0.3	0.7	1.7	1.3	-0.5	-0.3	1.1	0.6	-0.8	-1.2	0.8	-0.1
Respiratory disease	1.5	3.4	7.3	0.6	1.5	-1.6	0.2	2.7	-2.2	-2.6	2.2	1.2
Type 2 Diabetes (T2D) (2018)	0.3	0.6	1.9	0.4	1.4	-0.4	0.2	1.2	-1.0	-0.7	0.3	-0.4
Lung FEV1/FVC ratio	2.1	10.7	22.1	3.5	-3.7	4.7	4.5	-1.2	-1.2	3.2	-1.7	3.5
Lung FVC	1.8	9.2	21.0	-3.4	-1.8	0.3	-2.9	-4.1	4.6	2.7	-2.7	-2.6
Neuroticism	0.5	1.2	3.8	1.7	1.0	0.0	1.0	1.2	-1.9	-0.3	0.0	0.4
Chronotype (morning person)	2.4	5.5	13.0	1.9	-3.4	3.6	3.3	-1.7	-0.0	2.1	-0.8	1.5
Hair Pigment	0.0	0.5	2.0	-1.4	-0.1	-0.5	-0.9	0.2	-0.5	-1.0	0.5	-0.1
Tanning	0.2	2.8	7.6	-0.2	-1.9	1.8	0.2	-1.9	1.1	2.3	-2.8	0.2
Hand grip strength (left)	1.6	4.3	9.4	-0.1	-2.3	2.6	0.6	-2.7	1.7	3.1	-2.4	0.5
Number of treatments/medications taken	0.4	0.8	2.8	0.4	-0.9	1.1	0.7	0.6	-1.0	-0.2	0.0	1.7
Average weekly spirits intake	1.5	1.9	10.7	-0.4	0.9	-1.2	-1.2	-0.3	1.5	0.1	-0.1	-3.3
Sensitivity / hurt feelings	0.2	0.3	1.2	0.7	1.0	0.3	0.2	0.1	-1.1	0.2	-0.4	0.2
Frequency of depressed mood in last 2 weeks	0.9	1.2	3.5	1.9	-0.3	1.4	1.7	-0.2	-0.9	0.9	-0.8	0.6
Hearing difficulty/problems: Yes	0.5	0.8	1.8	0.4	-1.3	1.2	0.8	-0.7	0.6	1.1	-1.1	0.2
Relative age of first facial hair	0.8	1.6	4.6	1.7	0.2	0.9	1.6	0.9	-2.1	-0.0	0.1	1.7
Other serious medical condition/disability diagnosed by doctor	4.1	5.4	19.8	3.9	-2.9	1.8	4.5	-0.8	0.3	-0.2	-0.3	-0.9
Ever used hormone-replacement therapy (HRT)	0.5	0.6	1.2	-0.8	-1.1	0.8	-0.1	-1.0	0.4	1.1	0.4	0.3
Ever had hysterectomy (womb removed)	0.7	0.8	3.1	1.8	-0.7	0.4	1.5	0.2	-0.4	-0.3	-0.9	0.5
Systolic blood pressure, automated reading	0.5	1.5	5.5	0.4	-1.5	1.8	0.9	-0.0	-0.7	1.0	0.1	2.4
Eye problems/disorders: Diabetes related eye disease	3.0	3.3	10.3	1.2	-3.2	2.4	2.0	-1.8	0.3	2.0	-0.6	0.6
Angina	0.9	1.1	2.7	1.0	-0.8	1.2	1.3	0.1	-1.6	0.1	0.5	1.6
Medication for hormone replacement therapy	1.1	1.2	4.3	-1.3	-0.0	-1.1	-1.2	-0.8	2.1	-0.2	-0.5	-1.3
Vitamin and mineral supplements	0.2	0.3	1.3	0.1	-1.2	0.7	0.4	-0.3	0.7	0.2	0.2	-0.2
Supplements: Zinc	0.3	0.3	1.1	-0.4	0.1	-1.1	-0.4	0.1	0.2	-0.9	0.5	-0.6
Medication: Co-codamol	1.1	1.3	6.0	0.3	-1.0	0.6	0.5	0.5	-1.8	0.5	-0.5	2.5
Medication: Metformin	0.1	0.2	0.5	0.7	-0.4	0.4	0.4	-0.2	-0.4	-0.1	-0.5	0.1
Diabetes (father)	0.7	0.8	2.9	0.2	-0.5	-0.1	-0.6	-1.0	1.1	0.3	-1.2	-1.7
Diabetes (mother)	0.2	0.3	0.9	0.4	-0.8	1.0	0.2	-0.5	-0.2	0.6	-0.6	0.4
Severe depression (siblings)	0.9	1.0	2.6	-0.4	0.9	-0.6	-1.3	-1.1	1.6	0.6	-0.5	-1.4
Pack years adult smoking proportion	0.7	1.1	3.2	0.9	-0.8	1.8	0.8	-0.4	-0.9	1.2	-0.6	1.4
Impedance of leg (right)	0.1	0.7	2.4	-0.7	-0.4	-1.0	-0.2	0.2	-0.3	-1.4	1.6	-0.3
Leg fat-free mass (left)	0.9	4.6	11.7	3.2	2.1	-0.8	1.5	3.4	-2.8	-1.9	0.5	0.8
Trunk fat percentage	1.4	5.5	12.3	3.5	2.0	-1.3	1.8	3.5	-3.0	-2.2	1.5	0.2
Hand grip strength (right)	1.1	3.0	6.9	0.3	-2.5	2.6	1.3	-1.8	0.0	1.8	-1.6	1.7
Townsend deprivation index at recruitment	1.8	2.5	7.2	1.6	2.5	-0.4	0.4	2.7	-1.7	-1.2	1.0	0.9
Current tobacco smoking	1.7	2.8	8.0	1.7	0.6	1.8	2.1	1.0	-2.2	0.6	0.2	2.8
Average weekly fortified wine intake	1.8	2.1	4.5	-0.3	-1.2	0.8	-0.0	-1.9	2.1	1.8	-1.9	-1.4
Maternal smoking around birth	0.1	0.1	0.3	-0.2	0.3	-0.3	0.4	0.5	0.0	-0.4	-0.5	-0.0
Fed-up feelings	0.7	1.4	4.5	2.1	-0.4	0.7	1.7	0.7	-1.3	0.1	-0.2	1.4
Frequency of unenthusiasm / disinterest in last 2 weeks	2.0	2.7	7.9	1.6	-1.6	1.9	1.5	-1.0	0.2	2.0	-2.8	0.4
Relative age voice broke	0.9	1.4	4.0	2.0	0.1	0.9	1.4	0.9	-1.7	0.2	-0.6	1.3
Taking other prescription medications	0.2	0.3	1.1	-0.1	-1.0	-0.1	-0.0	-0.3	-0.4	-0.8	0.5	0.6
Age when periods started (menarche)	0.9	2.2	4.3	-1.4	-1.9	-0.1	-1.0	-1.9	2.1	0.6	-1.7	-1.2
Bilateral oophorectomy (both ovaries removed)	0.7	0.8	3.3	1.1	-0.3	0.9	0.7	0.3	-0.9	0.4	-0.1	1.8
Heel bone mineral density (BMD) T-score, automated (left)	1.4	3.2	8.4	-2.1	0.0	0.1	-2.8	-1.5	2.1	1.4	-2.9	0.2
Tinnitus: Yes, but not now, but have in the past	0.5	0.5	1.2	-0.8	0.1	-1.0	-1.1	0.3	0.7	-0.6	0.4	-0.7
Qualifications: CSEs or equivalent	1.0	1.3	5.9	-0.2	-1.0	0.7	-0.3	-1.4	0.0	1.6	-2.4	-0.3
Serious illness, injury or assault to yourself	1.9	2.4	8.0	2.5	-1.8	1.0	2.8	-0.4	0.7	0.2	-0.2	-1.4
High blood pressure	2.2	6.1	13.2	2.9	-1.8	3.2	3.4	0.7	-2.6	1.0	-0.1	3.6
Hayfever, allergic rhinitis or eczema	0.7	1.4	2.6	-1.2	1.6	-1.2	-1.6	1.4	-0.4	-1.2	0.9	0.4
Multivitamins +/- minerals	0.4	0.5	2.3	-0.6	1.5	-0.9	-1.0	0.2	-0.1	-0.4	0.3	0.1
Stomach or abdominal pain in last month	1.2	1.5	7.3	2.7	0.5	0.0	1.6	0.9	-1.1	-1.0	-0.2	-0.2
Supplements: Glucosamine	1.5	2.0	6.5	-1.0	-0.5	-0.6	-0.9	-1.8	2.5	0.9	-1.1	-2.0
Diverticular disease/diverticulitis (self-reported)	1.4	1.7	3.6	1.9	1.3	0.0	1.3	1.6	-1.9	-0.8	1.3	0.4
Medication: Atenolol	0.2	0.3	1.1	0.4	0.1	0.7	0.1	-0.1	-0.6	0.7	-0.4	1.1
Medication: Levothyroxine sodium	0.8	1.4	4.9	2.2	0.1	0.1	2.0	1.0	-0.7	-1.1	1.0	0.2
Sitting height	1.1	7.7	20.8	2.2	2.2	-1.4	1.6	4.6	-4.1	-3.4	1.7	1.7
Chronic bronchitis/emphysema (father)	0.6	0.7	1.7	0.2	-0.8	1.3	0.5	-0.9	0.2	1.1	-0.6	1.1
High blood pressure (mother)	0.7	1.0	4.2	2.1	-0.7	0.5	1.7	0.7	-0.7	-0.2	0.0	0.3
Body mass index (BMI)	0.7	3.1	11.0	3.3	1.8	-0.3	1.6	2.6	-1.7	-0.9	0.9	0.2
Impedance of leg (left)	0.2	0.8	2.2	-1.5	-0.2	-1.0	-0.9	-0.2	0.0	-1.1	1.2	-0.5
Leg predicted mass (left)	0.9	4.6	11.5	3.3	2.0	-0.7	1.6	3.4	-2.8	-1.8	0.4	0.8
Trunk fat mass	1.8	7.9	19.4	3.8	2.7	-1.7	1.8	4.4	-3.4	-2.9	1.8	0.4
Waist circumference	1.4	5.1	15.2	3.9	1.9	-0.8	2.0	3.3	-2.8	-1.7	1.0	0.4
Number of incorrect matches in round	2.5	4.2	12.7	-0.7	-1.9	2.5	-0.1	-2.7	1.3	3.6	-2.2	1.0
Past tobacco smoking	2.8	5.1	10.6	-2.0	-2.1	0.0	-1.4	-3.2	3.2	1.4	-2.2	-2.7
Alcohol usually taken with meals	1.9	3.0	7.5	0.4	-2.7	1.8	1.0	-2.4	1.6	2.4	-0.8	-0.8
Nervous feelings	1.9	3.6	7.2	1.9	2.7	-0.9	1.0	2.5	-2.4	-1.9	2.0	0.6
Frequency of tenseness / restlessness in last 2 weeks	0.2	0.2	0.7	0.5	-0.7	0.5	0.6	-0.4	-0.1	0.8	-0.0	-0.0
Hearing difficulty/problems with background noise	1.0	1.7	7.6	2.8	-0.8	1.2	2.0	0.2	0.4	0.6	-0.6	-0.2
Hair/balding pattern: Pattern 2	1.0	1.2	2.4	1.6	-0.2	0.1	1.5	0.9	-1.4	-1.2	1.4	0.4
Had menopause	2.2	2.7	5.9	1.7	1.0	-0.9	1.6	1.9	-1.9	-2.0	2.4	0.3
Had other major operations	1.4	1.7	7.3	2.7	-0.1	0.3	1.7	1.3	-0.9	-0.6	-1.1	0.9
Forced vital capacity (FVC)	0.2	0.6	2.4	-0.9	0.1	-0.5	-1.1	-0.0	0.6	0.3	-1.6	-0.4
Heel bone mineral density (BMD) T-score, automated (right)	1.5	3.5	11.8	-2.5	0.7	-1.0	-3.4	-0.9	2.4	0.9	-2.2	-0.4
Ever unenthusiastic/disinterested for a whole week	1.5	1.8	4.2	1.1	-1.6	2.0	1.5	-1.3	0.5	1.5	-1.4	0.8
Qualifications: None of the above	0.3	0.6	2.1	-0.9	0.8	-0.1	-1.4	0.3	-0.1	0.6	-1.0	0.4
Financial difficulties in last 2 years	0.8	1.1	2.7	-0.0	1.3	-1.7	-0.8	0.7	0.8	-0.9	1.2	-1.3
Mouth/teeth dental problems	0.2	0.3	1.0	-0.3	0.0	-1.0	-0.4	-0.1	0.2	-0.8	0.5	-0.9
Heart attack	0.9	1.2	3.4	-0.9	0.5	-1.8	-1.0	0.4	0.5	-1.5	-0.2	-1.6
Allergy	0.5	1.1	2.4	0.2	-1.4	1.1	0.9	-1.6	0.8	1.4	-1.0	-0.4
Pain all over the body in last month	1.2	1.3	3.3	-1.1	0.2	0.0	-0.9	-0.8	1.8	1.0	-1.5	-1.5
Diabetes (self-reported)	0.5	0.7	2.3	-0.4	1.1	-0.7	-1.2	0.0	0.3	0.0	-1.5	-1.0
Hayfever/allergic rhinitis (self-reported)	0.7	0.9	2.3	-1.5	1.0	-1.2	-1.4	0.4	0.3	-0.9	0.5	0.2
Medication: Ramipril	0.9	1.1	2.2	1.1	-1.4	1.5	1.4	-0.6	-1.0	0.8	0.2	0.9
Medication: Simvastatin	0.4	0.6	2.7	-0.5	-0.2	0.3	-0.0	0.7	-1.1	-0.4	0.6	1.6
Fluid intelligence score	3.0	6.2	12.2	1.1	2.8	-2.2	0.6	3.3	-2.6	-3.4	3.5	-0.2
Illnesses of siblings	1.2	1.7	4.0	-1.5	1.4	-0.8	-1.8	-0.7	2.0	0.5	-1.2	-1.1
Neuroticism score	0.5	1.0	3.4	1.6	0.9	0.1	1.0	0.9	-1.9	-0.2	0.4	0.4
Weight	2.0	9.6	23.1	4.5	2.7	-1.2	2.5	4.8	-4.0	-2.8	1.7	1.1
Impedance of arm (right)	0.1	0.5	2.0	-0.4	-0.3	-0.6	-0.1	0.3	-1.4	-1.1	0.7	0.5
Arm fat percentage (right)	1.0	4.1	13.4	3.7	1.8	-0.5	1.9	2.8	-2.5	-1.2	0.8	0.5
Trunk fat-free mass	0.9	5.4	13.9	3.0	2.0	-0.8	1.8	3.7	-2.9	-2.4	0.9	1.4
Hip circumference	1.3	5.4	15.5	3.9	2.1	-1.1	2.1	3.7	-2.4	-1.9	0.7	0.1
Time employed in main current job	1.9	2.2	9.9	0.3	-0.5	1.8	0.9	0.7	-2.0	0.5	-0.6	3.1
Alcohol intake versus 10 years previously	1.2	1.8	4.3	2.1	0.6	0.2	1.3	1.9	-1.9	-0.9	-0.1	1.3
Father’s age at death	2.8	3.7	9.7	0.3	2.0	-2.3	-0.3	2.0	-1.3	-3.1	2.9	0.1
Worrier / anxious feelings	0.6	1.1	4.3	0.7	0.5	1.1	0.8	0.4	-2.1	0.7	-0.0	1.5
Frequency of tiredness / lethargy in last 2 weeks	0.6	1.0	1.7	1.2	-1.2	0.9	1.3	-0.9	0.2	1.0	-1.1	-0.9
Falls in the last year	0.9	1.2	4.4	1.8	-0.0	0.5	2.1	1.1	-1.2	-0.3	0.1	0.8
Hair/balding pattern: Pattern 3	0.3	0.4	1.3	0.2	-0.3	0.3	0.3	-1.0	1.1	0.8	-0.5	-0.5
Number of live births	0.8	1.1	3.6	-0.9	1.0	-1.9	-1.6	0.5	0.9	-0.7	0.3	-0.3
Forced expiratory volume in 1-second (FEV1)	0.2	0.7	3.6	0.4	-0.8	0.7	0.3	-0.3	0.2	1.0	-1.9	0.4
Pulse rate	2.9	4.9	11.9	-1.0	-1.2	-0.2	-1.0	-2.8	3.4	1.4	-2.7	-3.4
Happiness	4.4	5.3	13.2	3.1	-2.8	2.9	3.6	-0.6	-1.5	1.1	-0.2	2.2
Noisy workplace	0.9	1.2	2.5	0.6	-0.7	1.1	0.4	-1.0	1.6	1.6	-1.5	0.4
Qualifications: A levels/AS levels or equivalent	1.7	3.7	12.0	3.5	-1.4	1.4	3.3	0.6	-1.8	-0.7	1.1	1.1
Serious illness, injury or assault of a close relative in last 2 years	0.8	0.9	3.6	-0.1	-1.9	0.4	0.9	-1.2	0.9	0.9	-0.4	-0.5
Mouth/teeth dental problems: Dentures	0.3	0.5	1.7	-0.2	0.9	-0.3	-0.5	1.0	-0.7	-0.6	0.5	1.3
Asthma	1.2	2.4	4.4	1.8	1.2	-0.7	1.0	1.9	-2.1	-1.8	2.0	0.8
Medication: Ibuprofen (e.g. Nurofen)	0.3	0.4	1.1	-0.9	-0.7	0.2	-0.3	-0.5	0.7	0.5	-0.7	-1.1
Medication: Cholesterol lowering	1.3	2.0	5.6	1.8	0.2	0.4	1.4	1.7	-2.4	-1.4	0.5	1.6
Depression (self-reported)	0.2	0.2	0.6	0.2	0.0	-0.5	0.3	0.6	-0.5	-0.6	0.3	-0.8
Medication: Lansoprazole	0.2	0.2	1.2	0.3	-0.2	0.1	0.1	-0.4	0.4	-0.2	-0.0	-1.1
Prospective memory result	2.1	2.6	13.1	1.0	-0.0	1.5	0.7	1.0	-2.2	0.5	0.6	3.6
Lung cancer (father)	1.5	1.7	3.8	0.7	1.4	-0.8	0.7	1.7	-1.9	-2.0	1.2	0.7
Illnesses of mother	0.2	0.2	0.9	0.3	0.1	-0.0	0.3	-0.1	0.9	-0.2	0.4	-0.8
Forced expiratory volume in 1-second (FEV1), Best measure	0.2	0.6	4.0	0.4	-0.5	0.5	0.2	-0.4	0.4	0.9	-2.0	-0.1
Pulse wave Arterial Stiffness index	2.8	3.3	9.6	1.7	2.1	-1.0	0.7	2.5	-1.2	-1.8	3.1	-0.3
Impedance of arm (left)	0.0	0.2	0.6	-0.4	-0.5	-0.6	-0.3	-0.3	-0.8	-0.6	0.2	-0.2
Arm fat mass (right)	1.4	6.0	17.7	4.2	2.1	-0.8	2.2	3.5	-3.0	-1.8	0.9	0.6
Trunk predicted mass	0.9	5.3	13.8	3.0	2.1	-0.9	1.8	3.7	-2.9	-2.4	0.9	1.3
Standing height	1.1	11.0	25.9	3.2	2.0	-1.9	2.2	5.0	-5.1	-4.3	1.8	1.9
Length of working week for main job	0.1	0.1	0.5	0.1	0.7	0.3	0.1	0.7	-0.3	0.3	0.1	0.2
Exposure to tobacco smoke at home	0.2	0.3	1.0	0.3	-0.0	0.6	-0.2	-0.6	0.6	1.0	-0.5	0.0
Breastfed as a baby	0.4	0.4	1.7	1.2	-0.2	0.2	1.3	-0.3	0.3	0.3	-0.5	-0.5
Tense / ‘highly strung’	1.1	1.7	6.1	0.2	2.5	-1.3	-0.9	1.4	-0.8	-0.9	1.5	-1.2
Seen doctor (GP) for nerves, anxiety, tension or depression	1.2	1.8	4.9	2.2	0.5	1.5	1.6	0.8	-1.2	0.8	-0.4	1.8
Hair/balding pattern: Pattern 4	0.6	1.4	4.0	-1.5	1.3	-0.4	-2.0	-0.7	1.2	0.8	-1.3	-0.6
Birth weight of first child	0.4	0.8	3.0	0.8	-1.1	0.9	1.7	-0.7	0.3	0.0	0.8	-0.3
Peak expiratory flow (PEF)	0.4	1.0	3.5	1.3	-0.8	0.9	0.7	-0.5	0.1	1.1	-1.9	0.2
Pulse wave reflection index	1.6	2.0	7.4	1.2	0.7	-0.4	0.9	1.7	-1.3	-1.4	2.7	0.9
Ever highly irritable/argumentative for 2 days	2.7	3.3	6.5	1.5	-2.2	2.5	1.8	-1.8	0.0	2.1	-1.9	1.2
Loud music exposure frequency	0.4	0.4	1.7	0.4	0.4	-0.1	0.4	0.8	-1.3	-0.1	0.9	0.2
Qualifications: O levels/GCSEs or equivalent	0.2	0.3	1.3	1.1	0.0	0.3	0.7	-0.2	-0.4	-0.3	0.5	0.3
Mouth/teeth dental problems: Bleeding gums	2.3	2.9	5.8	1.1	-1.9	2.4	1.4	-1.8	0.4	2.2	-2.3	0.8
Blood clot in the leg (DVT)	0.5	0.6	2.4	-0.7	0.9	-0.8	-0.9	-0.2	-0.2	0.1	-0.1	-1.6
Medication: Paracetamol	2.0	3.3	7.7	1.2	2.4	-1.5	0.5	2.8	-2.5	-2.0	1.5	0.0
Headache pain in last month	1.3	2.3	6.5	2.5	0.5	0.7	2.1	1.6	-2.2	-0.2	0.5	1.0
Medication for cholesterol, blood pressure or diabetes	1.6	2.7	5.2	-2.2	0.9	-2.0	-2.3	-0.6	2.0	-0.1	-0.1	-2.2
Glaucoma (self-reported)	2.7	3.2	8.0	-0.7	-1.1	0.2	-0.7	-2.6	2.8	1.7	-2.4	-1.7
Gout (self-reported)	0.5	0.7	1.9	1.4	-0.9	1.0	0.8	-0.5	0.2	0.6	-1.0	0.8
Hypothyroidism/myxoedema (self-reported)	0.4	0.8	2.7	0.6	-0.0	-0.6	0.8	0.9	-0.7	-1.6	1.4	-0.1
Medication: Amlodipine	3.7	5.2	10.2	2.7	-1.6	3.2	2.7	-0.0	-2.3	1.6	-1.0	3.2
Medication: Ventolin 100micrograms inhaler	1.0	1.3	2.9	-1.2	-0.3	0.6	-1.3	-1.7	1.1	1.2	-1.6	0.0
Birth weight	0.2	0.5	1.3	0.3	1.1	0.1	-0.3	1.1	-1.1	-0.7	0.4	-0.1
Chronic bronchitis/emphysema (mother)	0.3	0.4	1.2	0.5	-1.1	0.3	0.8	0.1	-0.5	0.0	0.1	0.9
High blood pressure (siblings)	1.1	1.6	3.7	1.8	-1.5	1.3	1.9	0.3	-1.3	0.2	0.9	1.1
Forced vital capacity (FVC), Best measure	0.1	0.5	1.9	-0.6	0.3	-0.7	-0.9	0.1	0.7	-0.0	-1.4	-0.6
Body fat percentage	1.3	5.1	11.8	3.4	2.0	-1.2	1.7	3.4	-2.8	-2.1	1.6	0.2
Leg fat percentage (right)	1.3	4.9	11.9	3.5	1.8	-1.1	1.9	3.3	-2.1	-2.1	2.0	-0.1
Arm fat-free mass (right)	0.8	4.2	10.8	3.1	1.7	-0.7	1.7	3.3	-2.4	-2.0	0.7	0.7
Exposure to tobacco smoke outside home	1.5	2.0	6.2	1.2	1.9	0.4	0.6	2.0	-2.5	-0.4	0.9	1.1
Comparative body size at age 10	0.1	0.4	1.4	-0.3	-0.1	-0.1	-0.6	0.1	0.3	1.2	-1.0	0.6
Number of full brothers	1.6	2.0	4.7	0.2	2.2	-1.7	-0.4	2.0	-1.3	-1.5	1.5	-0.3
Worry too long after embarrassment	0.8	1.3	3.1	1.7	-1.2	1.3	1.8	-1.1	-0.5	0.9	0.3	0.6
Seen a psychiatrist for nerves, anxiety, tension or depression	1.4	1.8	4.4	2.1	0.8	0.3	1.4	1.4	-1.6	-1.2	1.5	0.9
Wheeze or whistling in the chest in last year	0.5	1.0	5.1	0.1	0.7	-0.0	0.1	1.0	-2.3	-0.4	0.2	1.4
Number of children fathered	1.3	1.5	3.2	-1.8	0.5	-1.4	-1.7	-0.6	1.6	-0.0	-0.5	-1.3
Reason for reducing amount of alcohol drunk: Health precaution	3.2	3.8	7.9	0.0	-2.6	2.8	0.8	-1.9	0.1	2.5	-1.3	2.6
Age at first live birth	0.8	1.4	3.6	-1.1	0.8	-1.9	-0.9	0.1	1.3	-0.8	0.9	-1.7
Pulse wave peak to peak time	2.3	2.7	8.1	-1.5	-2.2	1.1	-0.4	-2.2	0.7	1.5	-2.9	0.6
Health satisfaction	2.1	2.7	9.1	1.6	-3.0	2.0	2.3	-1.2	0.2	1.3	-0.6	0.5
Shortness of breath walking on level ground	0.4	0.5	0.9	-0.7	-0.7	-0.1	-0.9	-0.9	0.7	0.5	-0.8	-0.6
Qualifications: College or University degree	0.5	1.6	5.3	1.7	-0.8	0.3	2.3	0.7	-0.0	-0.9	2.0	0.1
Eye problems/disorders: None of the above	2.4	2.8	5.9	0.9	2.3	-1.0	0.1	2.4	-1.9	-2.1	1.8	0.6
Mouth/teeth dental problems: Loose teeth	1.3	1.6	3.6	1.5	-1.0	1.9	1.5	-0.3	-0.9	1.0	-0.3	1.7
Emphysema/chronic bronchitis	0.4	0.5	1.1	0.5	0.8	-0.9	-0.3	0.6	0.2	-1.1	1.0	-0.3
Medication for pain relief, constipation, heartburn	1.6	2.8	6.9	-1.6	-1.1	0.7	-1.5	-2.6	2.1	2.1	-1.8	-0.2
Neck or shoulder pain in last month	0.3	0.5	2.1	-1.5	-0.8	0.1	-0.7	-0.1	0.0	0.2	-0.7	0.5
Medication: Blood pressure	2.5	4.5	10.3	2.5	-2.1	3.1	3.2	-0.4	-1.6	1.0	0.1	2.5
Angina (self-reported)	0.9	1.1	2.5	1.0	-0.8	1.4	1.3	-0.0	-1.6	0.1	0.5	1.4
Migraine (self-reported)	0.4	0.5	1.9	-0.3	0.1	-1.0	-0.4	1.4	0.0	-0.9	0.3	0.8
Medication: Ibuprofen	0.4	0.5	1.1	-0.9	-0.8	0.2	-0.2	-0.5	0.8	0.5	-0.8	-1.1
Medication: Allopurinol	0.8	1.0	3.3	1.8	-0.3	1.0	1.3	0.5	-1.0	0.1	-0.3	1.3
Medication: Omeprazole	2.1	2.5	8.1	2.4	-2.5	1.4	2.8	-0.7	-0.1	0.4	0.1	-0.2
Medication: Seretide 50 evohaler	0.4	0.5	1.2	0.1	1.0	-0.5	-0.7	1.1	-0.9	-0.7	0.1	0.5
Mean time to correctly identify matches	0.4	0.8	2.7	-0.7	0.2	0.7	-1.3	-1.2	0.5	1.6	-0.5	0.1
Heart disease (mother)	0.9	1.1	2.6	0.8	1.0	-0.8	0.5	1.3	-1.6	-1.2	1.2	0.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.4	0.4	2.6	0.1	-0.6	0.5	0.3	-0.0	-0.0	0.5	-0.5	1.6
Whole body fat mass	1.7	7.0	16.6	3.8	2.5	-1.5	1.9	4.1	-3.2	-2.6	1.6	0.2
Leg fat mass (right)	1.5	6.0	15.1	3.9	2.2	-1.1	2.1	3.7	-2.7	-2.2	1.7	0.2
Arm predicted mass (right)	0.8	4.3	11.6	3.0	1.9	-0.7	1.7	3.4	-2.5	-1.9	0.8	0.8
Pulse rate, automated reading	3.3	10.8	25.8	-1.3	-3.3	1.3	-0.7	-4.5	5.1	3.8	-3.6	-3.0
Alcohol intake frequency.	0.7	1.7	3.0	-1.0	-1.6	0.4	-1.0	-1.7	1.6	1.4	-1.7	0.2
Comparative height size at age 10	1.4	7.7	18.5	2.8	1.7	-0.9	1.9	4.1	-4.3	-3.0	2.1	2.3
Number of full sisters	3.5	4.3	10.2	-3.2	2.1	-2.9	-3.2	1.0	0.4	-1.9	0.4	-0.3
Suffer from ‘nerves’	3.0	4.7	11.8	2.0	2.3	-1.1	1.2	2.9	-3.4	-2.0	2.5	0.8
Overall health rating	1.4	3.1	10.4	2.7	-2.3	1.8	3.2	-0.3	-1.0	0.2	-0.4	0.5
Chest pain or discomfort	1.7	2.5	8.8	2.4	-1.1	1.5	3.0	0.4	-1.3	-0.3	1.1	1.0
Had major operations	0.8	0.9	2.2	1.4	-0.5	1.2	1.3	0.4	-0.1	0.7	-0.2	1.5
Age at last live birth	1.1	1.7	4.0	-1.8	0.5	-2.0	-1.6	-0.0	1.1	-1.1	0.9	-1.3
Family relationship satisfaction	2.7	3.3	11.0	2.9	-1.9	1.9	3.3	-0.4	-1.4	-0.4	1.0	0.7
Leg pain on walking	0.2	0.3	1.2	0.5	0.6	-0.2	0.1	0.4	0.0	0.5	-1.1	-0.3
Qualifications: NVQ or HND or HNC or equivalent	0.7	0.9	2.1	0.4	-1.2	1.5	1.2	-0.8	-0.9	0.3	0.1	1.2
Commuting to job workplace: Car/motor vehicle	0.3	0.3	0.9	0.9	-0.2	0.7	1.0	-0.2	-0.7	0.6	0.2	-0.0
Illness, injury, bereavement, stress in last 2 years	0.4	0.5	1.4	-1.1	0.6	0.2	-1.2	-0.2	-0.2	0.3	-0.6	0.9
Medication: Aspirin	1.0	1.3	3.3	0.4	0.5	-0.8	0.3	1.8	-1.2	-1.7	1.6	0.6
Supplements: Vitamin C	0.2	0.3	1.1	-0.2	0.8	-1.1	-0.7	0.5	-0.3	-0.1	-0.0	0.1
Knee pain experienced in last month	0.5	0.7	1.5	0.8	1.1	-1.2	-0.3	0.9	0.3	-0.3	-0.8	-1.2
Hypertension (Self-reported)	2.5	7.0	15.9	2.9	-2.0	3.4	3.6	0.7	-2.9	1.0	-0.0	4.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.3	0.4	1.3	0.6	-1.1	0.2	0.9	-0.1	-0.3	-0.6	0.8	0.2
Illnesses of father: Heart disease	1.3	1.9	5.2	-1.5	-1.0	0.9	-1.2	-1.7	2.3	1.5	-0.7	-0.5
Illnesses of siblings: Diabetes	0.2	0.2	0.6	-0.8	-0.3	-0.8	-0.3	0.2	-0.4	-0.4	-0.1	-0.5
Smoking status: Previous	2.9	4.4	11.3	1.6	2.3	-1.2	0.6	3.4	-2.3	-2.2	2.6	1.2
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.5	2.5	0.0	-0.6	0.1	-0.3	0.2	-0.8	0.1	-1.6	0.9
Whole body fat-free mass	0.9	5.0	12.7	3.2	2.0	-0.7	1.8	3.6	-2.9	-2.0	0.6	1.2
Leg fat-free mass (right)	0.7	3.9	9.8	3.0	2.1	-0.7	1.4	3.1	-2.7	-1.6	0.1	0.9
Arm fat percentage (left)	0.9	3.6	12.2	3.5	1.7	-0.6	1.7	2.7	-2.2	-1.1	0.7	0.1
Average weekly red wine intake	0.7	1.0	2.2	-0.9	-0.9	1.1	-0.3	-1.2	1.2	1.5	-0.7	0.5
Handedness (chirality/laterality): Left-handed	1.0	1.2	2.9	1.5	-0.3	1.4	1.5	-0.1	-0.9	0.7	0.1	1.7
Mood swings	0.3	0.5	1.3	1.0	0.4	0.1	0.6	0.9	-1.2	0.1	-0.5	0.6
Loneliness, isolation	0.6	0.8	1.8	0.6	-0.4	0.9	0.4	-1.3	0.8	1.3	-1.3	-0.4
Long-standing illness, disability or infirmity	1.6	2.5	7.1	2.4	-2.3	1.7	2.7	-0.6	-0.8	0.3	-0.1	0.3
Ever had bowel cancer screening	1.2	1.4	3.4	-0.6	1.2	-1.2	-0.9	1.8	-1.3	-1.3	0.8	1.0
Diabetes diagnosed by doctor	0.2	0.3	1.6	0.2	0.4	-0.1	-0.2	-0.1	-0.3	0.1	-1.3	-0.9
Ever had stillbirth, spontaneous miscarriage or termination	0.8	0.9	2.2	-1.5	-0.6	-1.0	-1.0	-0.7	1.4	-0.7	0.2	-0.8
Friendships satisfaction	1.7	2.1	5.5	2.2	-1.3	0.6	2.3	0.8	-1.3	-0.8	1.7	0.8
Qualifications: nursing, teaching	0.2	0.3	0.6	0.5	-0.8	-0.2	0.6	-0.7	-0.1	0.1	0.6	-0.4
Commuting to job workplace: Walk	0.2	0.2	0.9	-1.0	0.2	-0.3	-0.8	-0.5	0.2	-0.4	-0.1	0.1
Eye problems/disorders: Cataract	2.0	2.3	4.2	0.7	-1.9	2.0	1.3	-1.6	-0.1	2.0	-1.9	1.1
Mouth/teeth dental problems: Mouth ulcers	0.1	0.2	0.6	-0.7	-0.3	0.3	0.0	-0.3	0.8	0.5	-0.0	-0.2
Medication for cholesterol	0.1	0.1	0.7	0.1	-0.0	0.1	-0.1	-0.4	0.2	0.1	-0.3	-0.8
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.1	0.2	0.4	-0.5	-0.6	-0.2	-0.2	0.6	0.1	-0.6	-0.3	-0.2
Back pain experienced in last month	0.3	0.5	2.9	0.3	-0.4	-0.0	0.0	0.1	-0.5	0.0	-1.7	1.0
Mineral and other dietary supplements	1.4	1.8	4.2	1.2	-1.8	1.9	2.0	-0.7	0.1	1.2	-1.2	0.6
Breast cancer (self-reported)	1.1	1.4	4.0	-0.2	-1.3	1.0	0.3	-1.1	1.4	1.2	-2.0	-0.7
Asthma (self-reported)	1.3	2.6	4.6	1.7	1.4	-0.8	0.8	2.1	-2.1	-1.7	2.1	0.8
Osteoporosis (self-reported)	0.2	0.3	0.8	-0.9	-0.6	-0.0	0.0	-0.2	0.9	0.2	-0.1	-0.6
Osteoarthritis (self-reported)	0.3	0.4	1.5	0.9	0.1	-0.5	0.5	0.0	-0.3	-0.1	-1.2	-0.8
Medication: Aspirin	1.0	1.3	3.0	0.4	0.3	-0.7	0.4	1.7	-1.4	-1.6	1.6	0.7
Medication: Gliclazide	0.5	0.6	2.4	0.0	0.4	-0.6	-0.3	1.0	-1.5	-0.5	-0.6	0.5
Illnesses of father: None of the above (group 1)	0.5	0.6	1.4	1.1	0.4	-0.6	1.0	1.1	-1.2	-0.5	-0.2	-0.2
Smoking status: Current	1.7	2.7	8.0	1.4	0.8	1.9	1.9	0.9	-2.2	0.7	0.2	2.8
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.7	1.4	4.4	-0.9	1.1	-1.3	-1.3	0.2	1.5	0.1	-0.8	-2.1
Whole body water mass	0.9	5.2	13.2	3.2	2.0	-0.7	1.8	3.6	-3.0	-2.1	0.6	1.2
Leg predicted mass (right)	0.8	4.0	10.2	2.9	2.1	-0.8	1.3	3.2	-2.7	-1.6	0.2	0.8
Arm fat mass (left)	1.4	5.9	17.5	4.2	2.2	-0.8	2.1	3.5	-3.0	-1.8	0.8	0.5
Number of self-reported non-cancer illnesses	1.1	1.9	4.4	2.0	-0.6	0.5	2.1	1.2	-1.7	-0.9	0.5	1.6
Average weekly champagne plus white wine intake	2.9	4.0	9.7	2.6	-2.5	2.4	3.1	-0.9	-0.6	2.0	-1.2	1.1
Miserableness	2.2	3.7	9.4	2.9	-1.0	2.1	3.1	0.3	-1.5	1.4	-1.1	2.2
Guilty feelings	3.0	4.6	11.1	1.5	2.4	-2.3	0.5	2.8	-2.2	-3.3	2.0	-0.5
Wears glasses or contact lenses	2.6	2.9	10.5	1.4	-1.5	2.1	2.3	-0.2	-1.1	0.7	0.5	3.2
Ever taken oral contraceptive pill	1.3	1.4	3.3	1.4	1.2	0.9	0.9	1.3	-1.8	-0.3	-0.0	1.7
Hearing aid user	1.4	1.6	4.7	1.0	-2.2	1.8	1.0	-1.4	0.2	1.3	-0.8	-0.0
Mother’s age at death	0.6	0.7	2.1	-1.4	-0.7	-0.0	-1.2	-1.2	0.2	0.9	0.4	-0.5
Financial situation satisfaction	0.5	0.7	2.8	1.7	-0.1	0.7	1.2	0.2	-0.8	0.3	0.3	0.7
Tinnitus: Yes, now most or all of the time	0.4	0.5	1.2	-0.0	-0.6	0.8	-0.1	-0.3	0.2	1.1	-0.8	1.1
Commuting to job workplace: Public transport	0.4	0.5	1.0	0.5	-0.7	1.0	0.8	-0.6	1.0	0.3	-0.3	-0.6
Eye problems/disorders: Glaucoma	1.2	1.4	3.0	0.5	-0.8	0.9	0.5	-1.6	1.5	1.6	-1.7	-0.7
Medication: Blood pressure	1.2	2.3	6.4	1.4	0.4	0.4	1.4	1.9	-2.4	-0.8	0.9	2.5
Pain type(s) experienced in last month: Hip pain	1.6	2.1	5.6	1.3	-1.2	1.9	0.9	-0.8	-0.3	1.9	-2.4	1.1
Supplements: Fish oil (including cod liver oil)	2.7	3.5	5.9	-1.3	2.4	-2.4	-2.3	1.7	-0.7	-2.2	2.0	-0.4
High cholesterol (Self-reported)	1.9	3.4	10.9	1.7	-0.4	1.0	1.9	1.5	-3.3	-0.9	0.6	2.9
Medication: Bendroflumethiazide	0.8	1.2	2.6	0.9	0.1	0.2	1.2	1.4	-1.6	-1.2	0.9	1.2
Medication: Paracetamol	0.7	1.1	3.6	0.7	0.9	-0.5	0.7	1.4	-1.9	-1.2	0.8	0.2
Medication: Lisinopril	0.9	1.1	3.3	0.8	-1.4	1.2	1.2	0.1	-0.5	-0.1	1.0	1.8
Medication: Atorvastatin	2.1	2.6	7.0	1.8	0.3	0.9	1.3	1.7	-2.6	-0.4	-0.8	2.6
Illnesses of father: High blood pressure	0.9	1.2	3.8	1.1	0.2	0.8	1.1	0.9	-1.9	-0.7	0.9	1.1
Alcohol drinker status: Never	0.6	0.8	2.4	-1.6	-0.0	-0.0	-1.3	-0.8	0.3	0.8	-0.5	1.1
Ever smoked	2.6	4.6	9.8	1.6	1.9	-0.2	1.4	3.1	-3.1	-1.4	2.0	2.7
Basal metabolic rate	1.1	6.2	15.7	3.5	2.3	-0.9	1.9	4.0	-3.2	-2.3	0.8	1.1
Leg fat percentage (left)	1.1	3.9	9.7	2.8	2.0	-1.2	1.4	3.1	-2.0	-1.9	1.7	-0.2
Arm fat-free mass (left)	1.2	6.0	15.2	3.4	2.2	-0.8	1.9	3.9	-3.2	-2.3	0.7	1.3
Number of operations (self-reported)	1.7	2.5	7.6	2.8	0.8	-0.7	1.5	2.4	-1.4	-1.8	0.6	0.7
Average weekly beer plus cider intake	1.1	1.6	3.6	-1.1	1.9	-1.2	-1.6	1.1	-0.2	-1.6	0.9	-0.7
Irritability	0.4	0.7	2.3	1.5	0.6	0.3	0.5	1.1	-1.3	-0.0	-0.2	0.5
Risk taking	1.1	1.6	3.8	1.2	1.4	-1.5	0.4	1.3	-0.2	-1.9	1.3	-1.3
Ever had prostate specific antigen (PSA) test	0.5	0.6	1.7	-1.2	0.7	-0.7	-1.3	0.1	1.0	0.2	0.1	-0.3
Fractured/broken bones in last 5 years	2.2	2.9	9.4	0.9	0.7	-0.3	1.0	1.8	-2.5	-1.6	3.1	1.3
Age started oral contraceptive pill	1.0	1.3	4.0	0.5	1.0	-0.7	0.3	1.2	-1.4	-1.5	2.0	-0.1
Diastolic blood pressure, automated reading	1.0	3.1	7.4	-0.0	-2.4	0.9	0.2	-2.1	2.7	1.7	-2.1	-1.3
Ever depressed for a whole week	1.9	2.3	3.7	1.3	-1.9	1.8	1.2	-1.6	0.6	1.9	-1.8	0.9
Unable to work because of sickness or disability	1.1	1.4	2.9	1.7	-0.1	-0.4	1.4	1.2	-1.7	-1.3	1.2	0.5
Commuting to job workplace: Cycle	1.1	1.3	2.9	1.1	1.2	-1.1	0.3	1.7	-1.3	-1.5	0.9	-0.5
Myopia	1.1	1.6	3.8	0.5	-2.0	1.6	1.6	-0.3	-1.1	0.7	-1.3	1.3
Vascular/heart problems diagnosed by doctor	1.9	5.3	11.7	-2.8	1.4	-2.7	-3.2	-1.0	2.7	-0.6	-0.1	-3.4
Cholesterol lowering medication	0.9	1.3	5.2	0.1	-0.3	0.6	0.5	1.0	-2.0	-0.2	0.8	2.3
Medication: Omeprazole (e.g. Zanprol)	1.8	2.2	7.5	2.7	-2.0	1.1	2.7	-0.3	-0.5	0.2	-0.1	-0.1
Pain experienced in last month	0.3	0.5	1.4	-0.9	-0.0	-0.3	-0.7	-1.0	1.2	-0.2	0.2	-1.0
Supplements: Calcium	1.6	1.8	6.7	0.5	0.1	0.5	0.5	1.0	-2.5	-0.0	1.1	2.6
Basal cell carcinoma (self-reported)	1.2	1.4	5.0	2.2	-1.0	1.2	2.1	-0.4	0.3	0.6	-0.2	-0.2
Heart attack/myocardial infarction (self-reported)	0.7	0.9	2.7	-0.7	0.3	-1.6	-0.7	0.4	0.4	-1.4	-0.2	-1.3
Deep venous thrombosis (DVT) (self-reported)	0.6	0.7	2.6	-0.7	1.2	-1.0	-0.8	-0.0	-0.2	-0.1	-0.1	-1.6
Heart disease (siblings)	0.7	0.9	3.5	0.1	0.1	-0.9	0.1	0.6	-0.7	-1.7	1.9	-0.2
Alcohol drinker status: Previous	0.8	0.9	4.6	-0.0	-0.6	-0.1	0.6	1.0	-0.3	-1.1	2.1	0.8
Pack years of smoking	0.9	1.4	3.9	0.6	-1.0	2.0	0.6	-0.6	-0.8	1.4	-0.6	1.8
Impedance of whole body	0.1	0.4	1.0	-1.0	-0.6	-0.6	-0.4	-0.3	-0.5	-0.8	0.7	-0.2
Leg fat mass (left)	1.4	5.3	13.5	3.3	2.5	-1.3	1.5	3.7	-2.6	-2.1	1.5	0.1
Arm predicted mass (left)	1.2	5.9	15.5	3.4	2.3	-0.9	1.9	3.9	-3.1	-2.3	0.5	1.0